Ito Nobutoshi 伊藤暢聡

… Alternative Names

伊藤暢聡イトウノブトシ

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Researcher Number	40361703
Other IDs
Affiliation (Current)	2026: 東京科学大学, 総合研究院, 教授
Affiliation (based on the past Project Information) *help	2024: 東京科学大学, 総合研究院, 教授 2018 – 2024: 東京医科歯科大学, 難治疾患研究所, 教授
Review Section/Research Field	Principal Investigator Basic Section 54020:Connective tissue disease and allergy-related / Basic Section 49060:Virology-related Except Principal Investigator Basic Section 48040:Medical biochemistry-related / Basic Section 43040:Biophysics-related
Keywords	Principal Investigator 蛋白質間相互作用 / Ｘ線結晶構造解析 / 自己免疫疾患 / B細胞 / 構造生物学 / レトロウイルス / 抗ウイルス蛋白質 Except Principal Investigator Siglec / 細胞増殖 / 細胞接着 … More / LFA-1 / Glycocalyx / シスリガンド / シグナル伝達 / CD22 / B細胞 / シアル酸 / レクチン / 糖鎖 / 親和性予測 / 構造予測 / 分子動力学シミュレーション Less

Structural analyses of B-cell co-receptor related to SLEPrincipal Investigator
- Principal Investigator
  
  伊藤暢聡
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Institute of Science Tokyo
  Tokyo Medical and Dental University
Study on the molecular network cored by lectins on the B cell surface
- Principal Investigator
  
  TSUBATA Takeshi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 48040:Medical biochemistry-related
- Research Institution
  Nihon University
Complex structure and affinity prediction among cancer vaccine peptides and immune related proteins
- Principal Investigator
  
  Kamiya Narutoshi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 43040:Biophysics-related
- Research Institution
  University of Hyogo
Molecular mechanism of viral suppression by APOBEC3Principal Investigator
- Principal Investigator
  
  Ito Nobutoshi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49060:Virology-related
- Research Institution
  Tokyo Medical and Dental University

All 2024 2023 2022 2020

All Journal Article Presentation Patent

[Journal Article] CD72 is an inhibitory pattern recognition receptor that recognizes ribosomes and suppresses production of anti-ribosome autoantibody2024
- Author(s)
  Akatsu Chizuru、Tsuneshige Takahiro、Numoto Nobutaka、Long Wang、Uchiumi Toshio、Kaneko Yoshikatsu、Asano Masatake、Ito Nobutoshi、Tsubata Takeshi
- Journal Title
  
  Journal of Autoimmunity
  
  Volume: 146 Pages: 103245-103245
- DOI
  10.1016/j.jaut.2024.103245
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21H02679, KAKENHI-PROJECT-21K06045, KAKENHI-PROJECT-22K08560
[Journal Article] Neu5Gc-mediated high-affinity interaction is dispensable for CD22 cis-ligands to regulate B cell signaling2024
- Author(s)
  Akatsu Chizuru、Naito-Matsui Yuko、Abdu-Allah Hajjaj H.M.、Imamura Akihiro、Long Wang、Ishida Hideharu、Takematsu Hiromu、Tsubata Takeshi
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 300 Issue: 9 Pages: 107630-107630
- DOI
  10.1016/j.jbc.2024.107630
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H02679, KAKENHI-PROJECT-22K06135, KAKENHI-PROJECT-24K09371
[Journal Article] Structural basis of mutants of <scp>PET</scp> ‐degrading enzyme from <i>Saccharomonospora viridis</i> <scp>AHK190</scp> with high activity and thermal stability2020
- Author(s)
  Emori Miho、Numoto Nobutaka、Senga Akane、Bekker Gert‐Jan、Kamiya Narutoshi、Kobayashi Yuma、Ito Nobutoshi、Kawai Fusako、Oda Masayuki
- Journal Title
  
  Proteins: Structure, Function, and Bioinformatics
  
  Volume: 89 Issue: 5 Pages: 502-511
- DOI
  10.1002/prot.26034
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03229
[Patent] 免疫原性キャリア及び免疫原性組成物2023
- Inventor(s)
  鍔田武志、伊藤暢聡
- Industrial Property Rights Holder
  日本大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2023-173700
- Filing Date
  2023
- Data Source
  KAKENHI-PROJECT-21H02679
[Presentation] LFA-1 is a novel sialic acid-mediated cis-ligand of CD22 that regulates B cell activation and adhesion.2024
- Author(s)
  Hashadi Gamage, Amin Alborzian Deh Sheikh, Masatake Asano, Nobutoshi Ito, Takeshi Tsubata
- Organizer
  第54回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-21H02679
[Presentation] Crystal structure of B lymphocyte associated co-receptor human CD72-CTLD2024
- Author(s)
  Purnima Liyanage, Nobutaka Numoto, Yuya Hanazono, Takeshi Tsubata, Nobutoshi Ito
- Organizer
  第24回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-22K08560
[Presentation] Structure and function analysis of human B cell inhibitory co-receptor CD722023
- Author(s)
  Xibin Quan, Nobutaka Numoto, Takeshi Tsubata, Nobutoshi Ito
- Organizer
  The 23rd Annual Meeting of the Protein Science Society of Japan
- Data Source
  KAKENHI-PROJECT-22K08560
[Presentation] LFA-1 is a novel sialic acid-dependent cis-ligand of CD22 that regulates B cell proliferation.2023
- Author(s)
  Walakulu Gamage Hashadi Nadeesha, Amin Alborzian Deh Sheikh, Masatake Asano, Nobutoshi Ito, Takeshi Tsubata.
- Organizer
  2023年度日本生化学会関東支部例会
- Data Source
  KAKENHI-PROJECT-21H02679
[Presentation] Structure analysis of human B cell inhibitory co-receptor CD722022
- Author(s)
  Quan X., Numoto N., Tsubata T., Ito N.
- Organizer
  The 60th Annual Meeting of the Biophysical Society of Japan
- Data Source
  KAKENHI-PROJECT-22K08560
[Presentation] Structure analysis of human B cell inhibitory co-receptor CD72.2022
- Author(s)
  X. Quan, N. Numoto, T. Tsubata, N. Ito
- Organizer
  第60回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-21H02679
[Presentation] B細胞抑制性共受容体CD72のリガンド認識の分子機構2022
- Author(s)
  沼本修孝，全熙斌，鍔田武志，伊藤暢聡
- Organizer
  第95回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-22K08560
[Presentation] B細胞抑制性共受容体CD72のリガンド認識の分子機構2022
- Author(s)
  沼本修孝、全熙斌、鍔田武志、伊藤暢聡
- Organizer
  第95回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-21H02679

1. Kamiya Narutoshi (80420462)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
2. TSUBATA Takeshi (80197756)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
3. 織田昌幸 (20318231)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. Bekker Gerardu (80813758)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. 岩井佳子 (90362467)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 赤津ちづる (60735984)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results

Ito Nobutoshi 伊藤 暢聡

伊藤 暢聡 イトウ ノブトシ

Research Projects

Research Products

Co-Researchers

Structural analyses of B-cell co-receptor related to SLEPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Study on the molecular network cored by lectins on the B cell surface

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Complex structure and affinity prediction among cancer vaccine peptides and immune related proteins

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Molecular mechanism of viral suppression by APOBEC3Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] CD72 is an inhibitory pattern recognition receptor that recognizes ribosomes and suppresses production of anti-ribosome autoantibody2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Neu5Gc-mediated high-affinity interaction is dispensable for CD22 cis-ligands to regulate B cell signaling2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Structural basis of mutants of <scp>PET</scp> ‐degrading enzyme from <i>Saccharomonospora viridis</i> <scp>AHK190</scp> with high activity and thermal stability2020

Author(s)

Journal Title

DOI

Data Source

[Patent] 免疫原性キャリア及び免疫原性組成物2023

Inventor(s)

Industrial Property Rights Holder

Industrial Property Rights Type

Industrial Property Number

Filing Date

Data Source

[Presentation] LFA-1 is a novel sialic acid-mediated cis-ligand of CD22 that regulates B cell activation and adhesion.2024

Author(s)

Organizer

Data Source

[Presentation] Crystal structure of B lymphocyte associated co-receptor human CD72-CTLD2024

Author(s)

Organizer

Data Source

[Presentation] Structure and function analysis of human B cell inhibitory co-receptor CD722023

Author(s)

Organizer

Data Source

[Presentation] LFA-1 is a novel sialic acid-dependent cis-ligand of CD22 that regulates B cell proliferation.2023

Author(s)

Organizer

Data Source

[Presentation] Structure analysis of human B cell inhibitory co-receptor CD722022

Author(s)

Organizer

Data Source

[Presentation] Structure analysis of human B cell inhibitory co-receptor CD72.2022

Author(s)

Organizer

Data Source

[Presentation] B細胞抑制性共受容体CD72のリガンド認識の分子機構2022

Author(s)

Organizer

Data Source

[Presentation] B細胞抑制性共受容体CD72のリガンド認識の分子機構2022

Ito Nobutoshi 伊藤暢聡

伊藤暢聡イトウノブトシ