Yagishita Naoko 八木下尚子

… Alternative Names

八木下尚子ヤギシタナオコ

YAGISHITA Naoko 八木下尚子

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Researcher Number	40367389
Other IDs
Affiliation (Current)	2025: 聖マリアンナ医科大学, 医学研究科, 講師
Affiliation (based on the past Project Information) *help	2025: 聖マリアンナ医科大学, 医学研究科, 講師 2021 – 2023: 聖マリアンナ医科大学, 医学研究科, 講師 2016 – 2019: 聖マリアンナ医科大学, 医学研究科, 講師 2010 – 2015: 聖マリアンナ医科大学, 医学(系)研究科(研究院), 講師 2008 – 2011: St.Marianna University School of Medicine, 難病治療研究センター, 講師 … More 2009: 聖マリアンナ医大, 講師 2005 – 2006: 聖マリアンナ医科大学, 難病治療研究センター, 講師 2004: 聖マリアンナ医科大学, 難病治療研究センター, 助手 Less
Review Section/Research Field	Principal Investigator 膠原病・アレルギー・感染症内科学 / Basic Section 52020:Neurology-related / Pathological medical chemistry / Collagenous pathology/Allergology Except Principal Investigator 膠原病・アレルギー・感染症内科学 / Biological Sciences / Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields / Pathological medical chemistry
Keywords	Principal Investigator 滑膜細胞 / 関節リウマチ / シノビオリン / 小胞体関連分解 / E3ユビキチンリガーゼ / p53 / 自然免疫 / HTLV-1 / HAM / エネルギー代謝 … More / がん細胞 / E3ユビキチン化酵素 / apoptosis / KO mice / endoplasmic reticulum associated degradation / E3 ubiquitin ligase degradation / Synoviolin / synovial cells / rheumatoid arthritis / 肝細胞 / アポトーシス / 遺伝子改変マウス / 小胞体関連蛋白質分解 / 骨代謝 / 動物 / タンパク質 / 遺伝子 / 阻害剤 / 線維化 / 滑膜細菌 / Ets binding site / 自己免疫疾患 / シノビオリンプロモーター / 小胞体関連分解E3ユビキチンリガーゼ / 滑膜細胞増殖 / Synovial antigen X-2(Sax2) / 破骨細胞 / 骨粗鬆症 / 遺伝子欠損マウス / Synovial antige X-2(Sax2) / 基質 … More Except Principal Investigator シノビオリン / 関節リウマチ / 転写制御 / E3ユビキチンリガーゼ / 滑膜細胞増殖 / アポトーシス / 滑膜細胞 / ユビキチン / ユビキチン化 / ノックアウトマウス / 基質 / 小胞体 / ヒストン / PROTAC / フェノールポリマー / ユビキチンリガーゼ / DAMPs / 敗血症 / タンパク質分解 / 遺伝子改変動物 / サルコペニア / protein degradation / ubiquitin / apoptosis / endoreticulum / synovial cell / P53 / Rheumatoid arthritis / Synoviolin / シグナルネットワーク / リウマチ疾患モデル / ストレス / Ets因子 / 発現制御 / プロモーター / 蛋白分解 / p53 / T細胞 / 生化学的手法 / 化合物 / コンディショナルノックアウトマウス / 小胞体関連分解 / 分泌 / 滑膜細胞細胞 / サイトカイン / 肝硬変 / コンディショナルノックアウト / 慢性炎症 / 分泌タンパク質 / 線維化 / 小胞体ストレス / 転写複合体 / ESコビキチンリガーゼ / 遺伝子改変マウス / 造血 / ヘテロクロマチン / siRNA / 発癌 / MBD2 / RNAヘリケースA / 遺伝子発現制御 / DNAメチル化 / エピジェネティクス Less

HAMの新規発症機序としてのプロウイルス挿入による宿主遺伝子発現のシス攪乱の解明Principal Investigator
- Principal Investigator
  
  八木下尚子
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  St. Marianna University School of Medicine
Elucidation of a novel mechanism of HAM pathogenesis by targeting the innate immune systemPrincipal Investigator
- Principal Investigator
  
  Yagishita Naoko
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  St. Marianna University School of Medicine
Challenging the intracellular degradation of histones through the fusion of new technologies.
- Principal Investigator
  
  Kawahara Ko-ichi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
- Research Institution
  Osaka Institute of Technology
The study of physiological mechanisms of rheumatoid synovial cells by SynoviolinPrincipal Investigator
- Principal Investigator
  
  Yagishita Naoko
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  St. Marianna University School of Medicine
Involvement of Synoviolin in Muscle metabolism via two distinct pathways
- Principal Investigator
  
  Nakajima Toshihiro
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Tokyo Medical University
The study of bone destruction mechanism of rheumatoid arthritis by synoviolinPrincipal Investigator
- Principal Investigator
  
  YAGISHITA Naoko
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Collagenous pathology/Allergology
- Research Institution
  St. Marianna University School of Medicine
Synoviolin inhibitors for treatment of fibrosisPrincipal Investigator
- Principal Investigator
  
  YAGISHITA Naoko
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  St. Marianna University School of Medicine
二元的アポトーシス制御因子シノビオリンを標的としたがん研究
- Principal Investigator
  
  中島利博
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Choju Medical Institute, Fukushimura Hospital.
シノビオリンの二方向性シグナル制御の生物学的意義
- Principal Investigator
  
  中島利博
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Choju Medical Institute, Fukushimura Hospital.
Integrated study on implication of Synoviolin in multiprocesses of rheumatoid arthritis.
- Principal Investigator
  
  NAKAJIMA Toshihiro
- Project Period (FY)
  2008 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  Tokyo Medical University
  Choju Medical Institute, Fukushimura Hospital.
関節リウマチと骨粗鬆症の接点をなす分子複合体の機能解析Principal Investigator
- Principal Investigator
  
  八木下尚子
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  St. Marianna University School of Medicine
The transcriptional regulation of Synoviolin in rheumatoid synovial cells.Principal Investigator
- Principal Investigator
  
  YAGISHITA Naoko
- Project Period (FY)
  2008 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  St. Marianna University School of Medicine
滑膜細胞の小胞体機能亢進症 -関節リウマチの新しい病態モデルの提唱に向けた研究-
- Principal Investigator
  
  中島利博
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  St. Marianna University School of Medicine
The research of rheumatoid arthritis from aspect of developmental biology.Principal Investigator
- Principal Investigator
  
  YAGISHITA Naoko
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  St. Marianna University School of Medicine
発癌における新規転写統合装置複合体によるエピジェネティカルな遺伝子発現制御の研究
- Principal Investigator
  
  NAKAJIMA Toshihiro
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  St. Marianna University School of Medicine
Crosstalk between ER stress and p53 pathway
- Principal Investigator
  
  NAKAJIMA Toshihiro
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  St. Marianna University School of Medicine

[Book] New Developments in the Pathogenesis of Rheumatoid Arthritis2017
- Author(s)
  Yagishita N, Aratani S, Fujita H, Yamano Y, Nishioka K, Nakajima T.
- Total Pages
  150
- Publisher
  InTech
- ISBN
  9789535129691
- Data Source
  KAKENHI-PROJECT-17K08675
[Book] New Developments in the Pathogenesis of Rheumatoid Arthritis　Synoviolin is a novel pathogenic factor of arthropathy and chronic inflammation.2016
- Author(s)
  edited by Lazaros I. Sakkas　Yagishita N, Aratani S, Fujita H, Yamano Y, Nishioka K, Nakajima T.
- Total Pages
  151
- Publisher
  INTECH
- Data Source
  KAKENHI-PROJECT-16H05157
[Journal Article] Large-Scale Whole-Genome Analysis of HTLV-1-Associated Myelopathy Identified Hereditary Spastic Paraplegias2024
- Author(s)
  Takao Naoki、Yagishita Naoko、Araya Natsumi、Aratani Satoko、Yamauchi Junji、Takahashi Katsunori、Kunitomo Yasuo、Sato Tomoo、Nakamori Masahiro、Kawai Yosuke、Omae Yosuke、Tokunaga Katsushi、Matsuda Fumihiko、Mitsuhashi Satomi、Yamano Yoshihisa
- Journal Title
  
  Neurology Genetics
  
  Volume: 10 Issue: 1 Pages: 1-5
- DOI
  10.1212/nxg.0000000000200108
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K07507, KAKENHI-PROJECT-23K06954, KAKENHI-PROJECT-21K07427, KAKENHI-PROJECT-23K24248
[Journal Article] EZH1/2 dual inhibitors suppress HTLV-1-infected cell proliferation and hyperimmune response in HTLV-1-associated myelopathy2023
- Author(s)
  Koseki Akihito、Araya Natsumi、Yamagishi Makoto、Yamauchi Junji、Yagishita Naoko、Takao Naoki、Takahashi Katsunori、Kunitomo Yasuo、Honma Daisuke、Araki Kazushi、Uchimaru Kaoru、Sato Tomoo、Yamano Yoshihisa
- Journal Title
  
  Frontiers in Microbiology
  
  Volume: 14 Pages: 1175762-1175762
- DOI
  10.3389/fmicb.2023.1175762
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07507, KAKENHI-PROJECT-23K06954, KAKENHI-PROJECT-21K07427, KAKENHI-PROJECT-21K08386, KAKENHI-PROJECT-23K24248
[Journal Article] Human T-cell leukemia virus typeⅠ関連脊髄症患者レジストリ「HAMねっと」2023
- Author(s)
  八木下尚子, 山野嘉久.
- Journal Title
  
  神経治療学
  
  Volume: 40(1) Pages: 28-31
- Data Source
  KAKENHI-PROJECT-21K07427
[Journal Article] Long-term safety and efficacy of mogamulizumab (anti-CCR4) for treating virus-associated myelopathy2023
- Author(s)
  Sato T, Yamauchi J, Yagishita N, Araya N, Takao N, Ohta Y, Inoue E, Takahashi M, Yamagishi M, Suzuki Y, Uchimaru K, Matsumoto N, Hasegawa Y, Yamano Y.
- Journal Title
  
  Brain
  
  Volume: in press Issue: 8 Pages: 3181-3191
- DOI
  10.1093/brain/awad139
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08386, KAKENHI-PROJECT-22K07507, KAKENHI-PROJECT-23K06954, KAKENHI-PROJECT-21K07427, KAKENHI-PROJECT-23K24248
[Journal Article] HTLV-1関連脊髄症（HAM）診療ガイドライン2019」の活用実態および内容の評価に関する全国アンケート調査2023
- Author(s)
  鷹尾直誠, 佐藤知雄, 山内淳司, 八木下尚子, 堀部恵梨佳, 山野嘉久.
- Journal Title
  
  臨床神経学
  
  Volume: 63(7) Pages: 433-440
- Data Source
  KAKENHI-PROJECT-21K07427
[Journal Article] Efficacy of corticosteroid therapy for HTLV-1-associated myelopathy: A randomized controlled trial (HAMLET-P).2022
- Author(s)
  Yamauchi J, Tanabe K, Sato T, Nakagawa M, Matsuura E, Tsuboi Y, Tamaki K, Sakima H, Ishihara S, Ohta Y, Matsumoto N, Kono K, Yagishita N, Araya N, Takahashi K, Kunitomo Y, Nagasaka M, Coler-Reilly ALG, Hasegawa Y, Araujo A, Jacobson S, Grassi MFR, Galvao-Castro B, Bland M, Taylor GP, Martin F, Yamano Y.
- Journal Title
  
  Viruses
  
  Volume: in press Issue: 1 Pages: 136-136
- DOI
  10.3390/v14010136
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07983, KAKENHI-PROJECT-19K08004, KAKENHI-PROJECT-19K17049, KAKENHI-PROJECT-19H03575, KAKENHI-PROJECT-21K07427
[Journal Article] Health-related quality of life evaluation using the Short Form-36 in patients with human T-cell leukemia virus type 1-associated myelopathy.2022
- Author(s)
  Kimura M, Yamauchi J, Sato T, Yagishita N, Araya N, Aratani S, Tanabe K, Horibe E, Watanabe T, Coler-Reilly ALG, Nagasaka M, Akasu Y, Kaburagi K, Kikuchi T, Shibata S, Matsumoto H, Koseki A, Inoue S, Takata A, Yamano Y.
- Journal Title
  
  Front. Med(Lausanne)
  
  Volume: 9 Pages: 879379-879379
- DOI
  10.3389/fmed.2022.879379
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07427, KAKENHI-PROJECT-22K07507, KAKENHI-PROJECT-23K24248
[Journal Article] RAISING is a high-performance method for identifying random transgene integration sites.2022
- Author(s)
  Wada Y, Sato T, Hasegawa H, Matsudaira T, Nao N, Coler-Reilly ALG, Tasaka T, Yamauchi S, Okagawa T, Momose H, Tanio M, Kuramitsu M, Sasaki D, Matsumoto N, Yagishita N, Yamauchi J, Araya N, et al.
- Journal Title
  
  Commun Biol
  
  Volume: 5(1) Issue: 1 Pages: 535-535
- DOI
  10.1038/s42003-022-03467-w
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07427, KAKENHI-PROJECT-21K08386, KAKENHI-PROJECT-22K07507, KAKENHI-PROJECT-22K19232, KAKENHI-PROJECT-22K15420, KAKENHI-PROJECT-23K23768, KAKENHI-PROJECT-23K24233, KAKENHI-PROJECT-23K24248, KAKENHI-PROJECT-22H04923
[Journal Article] Potential Role of HTLV-1 Tax-Specific Cytotoxic T Lymphocytes expressing a Unique T-cell Receptor to Promote Inflammation of the Central Nervous System in Myelopathy Associated with HTLV-1.2022
- Author(s)
  Tanaka Y, Sato T, Yagishita N, Yamauchi J, Araya N, Aratani S, Takahashi K, Kunitomo Y, Nagasaka M, Kanda Y, Uchimaru K, Morio T, Yamano Y.
- Journal Title
  
  Front Immunol
  
  Volume: 13 Pages: 993025-993025
- DOI
  10.3389/fimmu.2022.993025
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07427, KAKENHI-PROJECT-22K07507, KAKENHI-PROJECT-22K07513, KAKENHI-PROJECT-23K24248, KAKENHI-PROJECT-22H04923
[Journal Article] Health-related quality of life evaluation using the Short Form-36 in patients with human T-cell leukemia virus type 1-associated myelopathy.2022
- Author(s)
  Kimura M, Yamauchi J, Sato T, Yagishita N, Araya N, Aratani S, Tanabe K, Horibe E, Watanabe T, Coler-Reilly A, Nagasaka M, Akasu Y, Kaburagi K, Kikuchi T, Shibata S, Matsumoto H, Koseki A, Inoue S, Takata A, Yamano Y.
- Journal Title
  
  Front Med
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K07427
[Journal Article] Clinical course of neurogenic bladder dysfunction in human T-cell leukemia virus type-1-associated myelopathy/tropical spastic paraparesis: A nationwide registry study in Japan.2021
- Author(s)
  Iijima N, Yamauchi J, Yagishita N, Araya N, Aratani S, Tanabe K, Sato T, Takata A, Yamano Y.
- Journal Title
  
  Orphanet J Rare Dis
  
  Volume: 16(1) Issue: 1 Pages: 355-355
- DOI
  10.1186/s13023-021-01990-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07983, KAKENHI-PROJECT-19K08004, KAKENHI-PROJECT-19K17049, KAKENHI-PROJECT-19H03575, KAKENHI-PROJECT-21K07427
[Journal Article] An update on human T-cell leukemia virus type I (HTLV-1)-associated myelopathy/tropical spastic paraparesis (HAM/TSP) focusing on clinical and laboratory biomarkers.2021
- Author(s)
  Yamauchi J, Araya N, Yagishita N, Sata t, Yamano Y.
- Journal Title
  
  Pharmacol Ther
  
  Volume: 218 Pages: 107669-107669
- DOI
  10.1016/j.pharmthera.2020.107669
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08004, KAKENHI-PROJECT-19K07983, KAKENHI-PROJECT-19K17049, KAKENHI-PROJECT-19H03575, KAKENHI-PROJECT-21K07427
[Journal Article] 患者レジストリの分類2020
- Author(s)
  八木下尚子、山野嘉久.
- Journal Title
  
  脳神経内科
  
  Volume: 92(3) Pages: 271-275
- Data Source
  KAKENHI-PROJECT-17K08675
[Journal Article] RADDAR-J Research and Developmental Group National platform for Rare Diseases Data Registry of Japan2019
- Author(s)
  Furusawa Y, Yamaguchi I, Yagishita N, Tanzawa K, Matsuda F, Yamano Y.
- Journal Title
  
  Learning Health Systems
  
  Volume: －
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05157
[Journal Article] Establishment of a Comprehensive Information Infrastructure and a Support Organization for Rare Disease Research in Japan (RADDAR-J).2019
- Author(s)
  Yamaguchi I, Furusawa Y, Kawaguchi T, Yagishita N, Tanzawa K, Yamano Y, Matsuda F.
- Journal Title
  
  Stud Health Technol Inform
  
  Volume: 264 Pages: 1080-1083
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08675
[Journal Article] Proposal of Classification Criteria for HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis Disease Activity.2018
- Author(s)
  Sato T, Yagishita N, Tamaki K, Inoue E, Hasegawa D, Nagasaka M, Suzuki H, Araya N, Ariella Coler-Reilly, Hasegawa Y, Tsuboi Y, Takata A, Yamano Y.
- Journal Title
  
  Front Microbiol
  
  Volume: 25(9) Pages: 1651-1651
- DOI
  10.3389/fmicb.2018.01651
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05157, KAKENHI-PROJECT-16H05323, KAKENHI-PROJECT-16K09701
[Journal Article] Identification of the inhibitory activity of E3 ligase Syvn1 in walnut extract.2018
- Author(s)
  Fujita H, Aratani S, Yagishita N, Nishioka K, Nakajima T.
- Journal Title
  
  Mol. Med. Rep.
  
  Volume: 8(6) Pages: 5701-5708
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05157
[Journal Article] Identification of the inhibitory activity of walnut extract on the E3 ligase Syvn1.2018
- Author(s)
  Fujita H, Aratani S, Yagishita N, Nishioka K, Nakajima T.
- Journal Title
  
  Mol. Med. Rep
  
  Volume: 8(6) Pages: 5701-5708
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08675
[Journal Article] Mogamulizumab (Anti-CCR4) in HTLV-1-Associated Myelopathy.2018
- Author(s)
  Sato T, Coler-Reilly ALG, Yagishita N, Araya N, Inoue E, Furuta R, Watanabe T, Uchimaru K, Matsuoka M, Matsumoto N, Hasegawa Y, Yamano Y.
- Journal Title
  
  N Engl J Med.
  
  Volume: 378(6) Issue: 6 Pages: 529-538
- DOI
  10.1056/nejmoa1704827
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09701, KAKENHI-PROJECT-16K09702, KAKENHI-PROJECT-17K19610, KAKENHI-PROJECT-16H05336, KAKENHI-PROJECT-16H05157, KAKENHI-PROJECT-16H05323, KAKENHI-PROJECT-16H06277
[Journal Article] 関節リウマチ発症因子シノビオリン.2017
- Author(s)
  八木下尚子，中島利博.
- Journal Title
  
  アレルギーの臨床
  
  Volume: 37（9） Pages: 72-78
- Data Source
  KAKENHI-PROJECT-17K08675
[Journal Article] Inhibitory effects of ubiquitination of synoviolin by PADI42017
- Author(s)
  Aratani S、Fujita H、Yagishita N、Yamano 、Okubo Y、Nishioka K、Nakajima T
- Journal Title
  
  Molecular Medicine Reports
  
  Volume: 16 Issue: 6 Pages: 9203-9209
- DOI
  10.3892/mmr.2017.7764
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08671, KAKENHI-PROJECT-17K08675
[Journal Article] Effectiveness of Daily Prednisolone to Slow Progression of HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis: A Multi-Center Retrospective Cohort Study.2017
- Author(s)
  Coler-Reilly ALG, Sato T, Matsuzaki T, Nakagawa M, Niino M, Nagai M, Nakamura T, Takenouchi N, Araya N, Yagishita N, Inoue E, Yamano Y.
- Journal Title
  
  Neurotherapeutics
  
  Volume: 14(4) Issue: 4 Pages: 1084-1094
- DOI
  10.1007/s13311-017-0533-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09701, KAKENHI-PROJECT-16K09702, KAKENHI-PROJECT-16H05157, KAKENHI-PROJECT-16H05323
[Journal Article] Inhibitory effects of ubiquitination of synoviolin by PADI4.2017
- Author(s)
  Aratani S, Fujita H, Yagishita N, Yamano Y, Okubo Y, Nishioka K, Nakajima T
- Journal Title
  
  Mol. Med. Rep
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05157
[Journal Article] 関節リウマチ発症因子シノビオリン2017
- Author(s)
  八木下尚子, 中島利博.
- Journal Title
  
  アレルギーの臨床
  
  Volume: 37(2) Pages: 94-100
- Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26461478
[Journal Article] 「アレルギーの臨床」に寄せる-885-「関節リウマチ発症因子シノビオリン」2017
- Author(s)
  八木下尚子、中島利博
- Journal Title
  
  アレルギーの臨床
  
  Volume: 37(9) Pages: 72-78
- Data Source
  KAKENHI-PROJECT-16H05157
[Journal Article] 関節リウマチ発症因子シノビオリン2017
- Author(s)
  八木下尚子、中島利博
- Journal Title
  
  アレルギーの臨床
  
  Volume: 37 (2) Pages: 94-100
- Data Source
  KAKENHI-PROJECT-17K08675
[Journal Article] 関節リウマチ発症因子シノビオリン2016
- Author(s)
  八木下尚子, 中島利博.
- Journal Title
  
  アレルギーの臨床
  
  Volume: 36(13) Pages: 84-90
- Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26461478
[Journal Article] 関節リウマチ発症因子シノビオリン2016
- Author(s)
  八木下尚子, 中島利博
- Journal Title
  
  BIO Clinica　慢性炎症と疾患
  
  Volume: 5(3) Pages: 137-143
- Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26461478
[Journal Article] Inhibitory effects of ubiquitination of synoviolin by PADI42016
- Author(s)
  *Aratani S, Fujita H, Yagishita N, Yamano Y, Okubo Y, Nishioka K, Nakajima T
- Journal Title
  
  Mol. Med. Rep. in press
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461478
[Journal Article] Mitochondrial Ubiquitin Ligase Activator of NF-κB (MULAN) regulates NF-κB signaling in ER stress-stimulated cells.2016
- Author(s)
  Fujita H, Aratani S, Fujii R, Yamano Y, Yagishita N, Araya N, Izumi T, Azakami K, Hasegawa D, Nishioka K and Nakajima T
- Journal Title
  
  Int J Mol Med.
  
  Volume: 37 Issue: 6 Pages: 1611-1618
- DOI
  10.3892/ijmm.2016.2566
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461476, KAKENHI-PROJECT-15K15091, KAKENHI-PROJECT-26670479, KAKENHI-PROJECT-25305032, KAKENHI-PROJECT-16H05157, KAKENHI-PROJECT-16H05845, KAKENHI-PROJECT-25461490, KAKENHI-PROJECT-26461478
[Journal Article] Synoviolin inhibitor LS-102 reduces endoplasmic reticulum stress-induced collagen secretion in an in vitro model of stress-related interstitial pneumonia.2015
- Author(s)
  Nakajima F, Aratani S, Fujita H, Yagishita N, Ichinose S, Makita K, Setoguchi Y, Nakajima T.
- Journal Title
  
  Int J Mol Med.
  
  Volume: 35 Issue: 1 Pages: 110-6
- DOI
  10.3892/ijmm.2014.1984
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24592282, KAKENHI-PROJECT-25305032, KAKENHI-PROJECT-26461476, KAKENHI-PROJECT-26461478
[Journal Article] The E3 ligase synoviolin controls body weight and mitochondrial biogenesis through negative regulation of PGC-1β.2015
- Author(s)
  Fujita H, Yagishita N, Aratani S, Saito-Fujita T, Morota S, Yamano Y, Hansson MJ, Inazu M, Kokuba H, Sudo K, Sato E, Kawahara K, Nakajima F, Hasegawa D, Higuchi I, Sato T, Araya N, Usui C, Nishioka K, Nakatani Y, Maruyama I, Usui M, Hara N, Uchino H, Elmer E, Nishioka K, Nakajima T.
- Journal Title
  
  EMBO J.
  
  Volume: 34 Issue: 8 Pages: 1042-55
- DOI
  10.15252/embj.201489897
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24592282, KAKENHI-PROJECT-26293387, KAKENHI-PROJECT-26461476, KAKENHI-PROJECT-26670479, KAKENHI-PROJECT-26670793, KAKENHI-PROJECT-26461478, KAKENHI-PROJECT-26461961, KAKENHI-PROJECT-15K15091, KAKENHI-PROJECT-25860726, KAKENHI-PROJECT-25461293, KAKENHI-PROJECT-25461294, KAKENHI-PROJECT-15K15667, KAKENHI-PROJECT-24790898, KAKENHI-PROJECT-25305032, KAKENHI-PROJECT-26293385
[Journal Article] Hrd1 suppresses Nrf2-mediated cellular protection during liver cirrhosis.2014
- Author(s)
  Wu T, Zhao F, Gao B, Tan C, Yagishita N, Nakajima T, Wong PK, Chapman E, Fang D, Zhang DD.
- Journal Title
  
  Genes Dev
  
  Volume: 28(7) Issue: 7 Pages: 708-722
- DOI
  10.1101/gad.238246.114
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23659502, KAKENHI-PROJECT-24592282, KAKENHI-PROJECT-25305032, KAKENHI-PROJECT-26461478
[Journal Article] The Japanese version of the modified ACR preliminary diagnostic criteria for fibromyalgia and the fibromyalgia symptom scale : reliability and validity2013
- Author(s)
  Usui C, Hatta K, Aratani S, Yagishita N, Nishioka K, Kanazawa T, Itoh K, Yamano Y, Nakamura H, Nakajima T, Nishioka K
- Journal Title
  
  Mod Rheumatol
  
  Volume: 23(5) Issue: 5 Pages: 846-850
- DOI
  10.1007/s10165-012-0759-x
- NAID
  10031201138
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390160, KAKENHI-PROJECT-23659502, KAKENHI-PROJECT-24791006, KAKENHI-PROJECT-25670295
[Journal Article] RING finger type E3 ubiquitin ligase inhibitors as novel candidates for the treatment of rheumatoid arthritis2012
- Author(s)
  Yagishita N, Aratani S, Leach C, Amano T, Yamano Y, Nakatani K, Nishioka K, Nakajima T
- Journal Title
  
  Int J Mol Med
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249052
[Journal Article] RING-finger type E3 ubiquitin ligase inhibitors as novel candidates for the treatment of rheumatoid arthritis.2012
- Author(s)
  Yagishita N., Aratani S., Leach C., Amano T., Yamano Y., Nakatani K., Nishioka K. and Nakajima T
- Journal Title
  
  Int. J. Mol. Med
  
  Volume: 30 Issue: 6 Pages: 1281-1286
- DOI
  10.3892/ijmm.2012.1129
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659176, KAKENHI-PROJECT-23659502, KAKENHI-PROJECT-24791006
[Journal Article] Fucoidan therapy decreases the proviral load in patients with human T-lymphotropic virus type1-associated neurological disease2011
- Author(s)
  Araya N, Takahashi K, Sato T, Nakamura T, Sawa C, Hasegawa D, Ando H, Aratani S, Yagishita N, Fujii R, Oka H, Nishioka K, Nakajima T, Mori N, Yamano Y
- Journal Title
  
  Antivir Ther
  
  Volume: 16 Pages: 89-98
- URL
  http://www.intmedpress.com/serveFile.cfm?sUID=eda7bacc-605e-4dd6-b2aa-f62abc29e554
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249052
[Journal Article] Prostaglandin EP2 receptor signalling inhibits the expression of matrix metalloproteinase 13 in human osteoarthritic chondrocytes2011
- Author(s)
  Sato T, Konomi K, Fujii R, Aono H, Aratani S, Yagishita N, Araya N, Yudoh K, Beppu M, Yamano Y, Nishioka K, Nakajima T
- Journal Title
  
  Ann Rheum Dis
  
  Volume: 70 Issue: 1 Pages: 221-22
- DOI
  10.1136/ard.2009.118620
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249052, KAKENHI-PROJECT-22590943, KAKENHI-PROJECT-22790833, KAKENHI-PROJECT-23659176
[Journal Article] E3 Ubiquitin Ligase Synoviolin Is Involved in Liver Fibrogenesis2010
- Author(s)
  Hasegawa D, Fujii R, Yagishita N, Matsumoto N, Aratani S, Izumi T, Azakami K, Nakazawa M, Fujita H, Sato T, Araya N, Koike J, Tadokoro M, Suzuki N, Nagata K, Senoo H, Friedman SL, Nishioka K, Yamano Y, Itoh F, Nakajima T
- Journal Title
  
  PLoS One
  
  Volume: 5(10)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20689019
[Journal Article] E3 ubiquitin ligase synoviolin is involved in liver fibrogenesis2010
- Author(s)
  Hasegawa D, Fujii R, Yagishita N, Matsumoto N, Aratani S, Izumi T, Azakami K, Nakazawa M, Fujita H, Sato T, Araya N, Koike J, Tadokoro M, Suzuki N, Nagata K, Senoo H, Friedman SL, Nishioka K, Yamano Y, Itoh F, Nakajima T
- Journal Title
  
  PLoS One
  
  Volume: 5 Issue: 10 Pages: e13590-e13590
- DOI
  10.1371/journal.pone.0013590
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249052, KAKENHI-PROJECT-22590943, KAKENHI-PROJECT-22790833
[Journal Article] E3 ubiquitin ligase synoviolin is involved in liver fibrogenesis2010
- Author(s)
  Hasegawa D, Fujii R, Yagishita N, Matsumoto N, Aratani S, Izumi T, Azakami K, Nakazawa M, Fujita H, Sato T, Araya N, Koide J, Tadokoro M, Suzuki N, Friedman SL, Nishioka K, Yamano Y, Itoh F, Nakajima T
- Journal Title
  
  PLoS One 5(10)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249052
[Journal Article] Increased Prevalence of Group A b-hemolytic Streptococcus Among Ethnic Population in Kyrgyzstan Defined by Rapid Antigen Detection Test2009
- Author(s)
  中島利博、八木下尚子、上昌広、丸山征郎、山野嘉久, 他12名
- Journal Title
  
  Molecular Medicine Reports 1(6)
  
  Pages: 869-874
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249052
[Journal Article] Increased Prevalence of Group A b-hemolnytic Streptococcus Among Ethnic Population in Kyrgyzstan Defined by Rapid Antigen Detection Test.2009
- Author(s)
  中島利博、八木下尚子、丸山征郎、山野嘉久他13名
- Journal Title
  
  Molecular Medicine Reports 1(6)
  
  Pages: 869-874
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20059033
[Journal Article] Activation of synoviolin promoter in rheumatoid synovial cells by a novel transcription complex of interleukin enhancer binding factor 3 and GA binding protein alpha.2009
- Author(s)
  Izumi T, Fujii R, Izumi T, Nakazawa M, Yagishita N, Tsuchimochi K, Yamano Y, Sato T, Fujita H, Aratani S, Araya N, Azakami K, Hasegawa D, Kasaoka S, Tsuruta R, Yokouti M, Ijiri K, Beppu M, Maruyama I, Nishioka K, Maekawa T, Komiya S, Nakajima T
- Journal Title
  
  Arthritis Rheum. 60(1)
  
  Pages: 63-72
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249052
[Journal Article] Abnormally high levels of virusinfected IFN-gamma+CCR4+CD4+CD25+T cells in a retrovirus-associated neuroinflammatory disorder2009
- Author(s)
  Yamano Y, Araya N, Sato T, Utsunomiya A, Azakami K, Hasegawa D, Izumi T, Fujita H, Aratani S, Yagishita N, Fujii R, Nishioka K, Jacobson S, Nakajima T
- Journal Title
  
  PLoS One
  
  Volume: 4 Issue: 8 Pages: e6517-e6517
- DOI
  10.1371/journal.pone.0006517
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249052
[Journal Article] An E3 ubiquitin ligase, Synoviolin, is involved in the degradation of immature nicastrin, and regulates the production of amyloid beta-protein2009
- Author(s)
  Maeda T, Marutani T, Zou K, Araki W, Tanabe C, Yagishita N, Yamano Y, Amano T, Michikawa M, Nakajima T, Komano H
- Journal Title
  
  FEBS J
  
  Volume: 276 Issue: 20 Pages: 5832-5840
- DOI
  10.1111/j.1742-4658.2009.07264.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249052
[Journal Article] Role of Kenae/CCDC125 in cell motility through the deregulation of RhoGTPase2009
- Author(s)
  Araya N, Arimura H, Kawahara K, Yagishita N, Ishida J, Fujii R, Aratani S, Fujita H, Sato T, Yamano Y, Higuchi I, Osame M, Nishioka K, Fukamizu A, Arimura K, Maruyama I, Nakajima T.
- Journal Title
  
  Int J Mol Med
  
  Volume: 24 Issue: 05 Pages: 605-611
- DOI
  10.3892/ijmm_00000271
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249052, KAKENHI-PROJECT-23659176
[Journal Article] Increased Prevalence of Group A b-hemolytic Streptococcus Among Ethnic Population in Kyrgyzstan Defined by Rapid Antigen Detection Test.2009
- Author(s)
  中島利博、八木下尚子、丸山征郎、山野嘉久他13名
- Journal Title
  
  Molecular Medicine Reports 1(6)
  
  Pages: 869-874
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20013045
[Journal Article] Activation of synoviolin promoter in rheumatoid synovial cells by a novel transcription complex of interleukin enhancer binding factor 3 and GA binding protein alpha2009
- Author(s)
  Izumi T, Fujii R, Izumi T, Nakazawa M, Yagishita N, Tsuchimochi K, Yamano Y, Sato T, Fujita H, Aratani S, Araya N, Azakami K, Hasegawa D, Kasaoka S, Tsuruta R, Yokouti M, Ijiri K, Beppu M, Maruyama I, Nishioka K, Maekawa T, Komiya S, Nakajima T
- Journal Title
  
  Arthritis Rheum
  
  Volume: 60 Issue: 1 Pages: 63-72
- DOI
  10.1002/art.24178
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249052
[Journal Article] Severe loss of invariant NKT cells exhibiting anti-HTLV-1 activity in patients with HTLV-1-associated disorders2009
- Author(s)
  Azakami K, Sato T, Araya N, Utsunomiya A, Kubota R, Suzuki K, Hasegawa D, Izumi T, Fujita H, Aratani S, Fujii R, Yagishita N, Kamijuku H, Kanekura T, Seino K, Nishioka K, Nakajima T, Yamano Y
- Journal Title
  
  Blood
  
  Volume: 114 Issue: 15 Pages: 3208-3321
- DOI
  10.1182/blood-2009-02-203042
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249052
[Journal Article] Activation of Synoviolin Promoter in Rheumatoid Synovial Cells by a Novel Transcription Complex of Interleukin Enhancer Binding Factor 3 and GA Binding Protein2009
- Author(s)
  Izumi T, Fujii R, Izumi T, Nakazawa M, Yagishita N, Tsuchimochi K, Yamano Y, Sato T, Fujita H, Aratani S, Araya N, Azakami K, Hasegawa D, Kasaoka S, Tsuruta R, Yokouti M, jiri K, Beppu M, Maruyama I, Nishioka K, Maekawa T, Komiya S, Nakajima T
- Journal Title
  
  Arthritis Rhe
  
  Volume: 60(1) Pages: 63-72
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20689019
[Journal Article] Synoviolin, protein folding and the maintenance of joint homeostasis2008
- Author(s)
  中島利博、八木下尚子他2名
- Journal Title
  
  Nature Clin Prac Rheum 4(2)
  
  Pages: 91-97
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20013045
[Journal Article] Novel transcriptional complex of ILF3-GABP α activates synoviolin promoter in rheumatoid synovial cells2008
- Author(s)
  中島利博、八木下尚子、山野嘉久、丸山征郎他19名
- Journal Title
  
  A&R 60
  
  Pages: 63-72
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20013045
[Journal Article] Novel transcriptional complex of ILF3-GABP α activates synoviolin promoter in rheumatoid synovial cells2008
- Author(s)
  中島利博、八木下尚子、山野嘉久、丸山征郎他19名
- Journal Title
  
  A&R 60
  
  Pages: 63-72
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20059033
[Journal Article] Increased prevalence of group Aβ-hemolytic streptococcus among an ethnic population in Kyrgyzstan detected by the rapid antigen detection test2008
- Author(s)
  Omurzakova OA, Yamano Y, Sato T, Izumi T, Azakami K, Hasegawa D, Fujii R, Yagishita N, Aratani S, Kabaeva ZS, Mirrakhimov MM, Kami M, Maruyama I, Osame M, Yokota S, Nishioka K, Nakajima T
- Journal Title
  
  Molecular Medicine Reports
  
  Volume: 1 Pages: 869-874
- DOI
  10.3892/mmr_00000043
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249052
[Journal Article] Synoviolin, protein folding and the maintenance of joint homeostasis2008
- Author(s)
  Yagishita N, Yamasaki S, Nishioka K, Nakajima T.
- Journal Title
  
  Nature Clin Prac Rheum 4
  
  Pages: 91-97
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249052
[Journal Article] Novel transcriptional complex of ILF3-GABP α activates synoviolin promoter in rheumatoid synovial cells2008
- Author(s)
  中島利博、八木下尚子、山野嘉久、丸山征郎, 他19名
- Journal Title
  
  A&R 60
  
  Pages: 63-72
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249052
[Journal Article] Synoviolin, protein folding and the maintenance of joint homeostasis2008
- Author(s)
  Yagishita N, Yamasaki S, Nishioka K, Nakajima T
- Journal Title
  
  Nature Clin Prac Rheum
  
  Volume: 4 Issue: 2 Pages: 91-97
- DOI
  10.1038/ncprheum0699
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249052
[Journal Article] Synoviolin, protein folding and the maintenance of Joint homeostasis2008
- Author(s)
  中島利博、八木下尚子, 他2名
- Journal Title
  
  Nature Clin Prac Rheum 4(2)
  
  Pages: 91-97
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249052
[Journal Article] Synoviolin, protein folding and the maintenance of joint homeostasis2008
- Author(s)
  中島利博、八木下尚子他2名
- Journal Title
  
  Nature Clin Prac Rheum 4(2)
  
  Pages: 91-97
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20059033
[Journal Article] Cytoplasmic destruction of p53 by the endoplasmic reticulum-resident ubiquitin ligase 'Synoviolin'.2007
- Author(s)
  Yamasaki S, Yagishita N, Sasaki T, Nakazawa M, Kato Y, Yamadera T, Bae E, Toriyama S, Ikeda R, Zhang L, Fujitani K, Yoo E, Tsuchimochi K, Ohta T, Araya N, Fujita H, Aratani S, Eguchi K, Komiya S, Maruyama I, Higashi N, Sato M, Senoo H, Ochi T, Yokoyama S, Amano T, Kim J, Gay S, Fukamizu A, Nishioka K, Tanaka K, Nakajima T
- Journal Title
  
  EMBO J 26(1)
  
  Pages: 113-22
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249052
[Journal Article] Role of Synoviolin in rheumatoid arthritis : possible clinical relevance2006
- Author(s)
  Naoko Yagishita, et al.
- Journal Title
  
  Future Rheumatology 1・1
  
  Pages: 31-36
- Data Source
  KAKENHI-PROJECT-17659304
[Journal Article] Role of Synoviolin in rheumatoid arthritis : possible clinical relevance2006
- Author(s)
  Naoko Yagishita, et al.
- Journal Title
  
  Future Rheumatology 1・1
  
  Pages: 31-36
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390290
[Journal Article] Role of Synoviolin in rheumatoid arthritis : possible clinical relevance2006
- Author(s)
  Naoko Yagishita, et al.
- Journal Title
  
  Future Rheumatology 1.1
  
  Pages: 31-36
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390290
[Journal Article] Role of Synoviolin in rheumatoid arthritis : possible clinical relevance2006
- Author(s)
  Naoko Yagishita et al.
- Journal Title
  
  Future Rheumatol 1・1
  
  Pages: 31-36
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591058
[Journal Article] Role of Synoviolin in rheumatoid arthritis : possible clinical relevance2006
- Author(s)
  Naoko Yagishita et al.
- Journal Title
  
  Future Rheumatol 1
  
  Pages: 31-36
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591058
[Journal Article] Essential Role of Synoviolin in Embryogenesis2005
- Author(s)
  Naoko Yagishita, et al.
- Journal Title
  
  J Biol.Chem 280
  
  Pages: 7909-7916
- Data Source
  KAKENHI-PROJECT-16390290
[Journal Article] Essential Role of Synoviolin in Embryogenesis2005
- Author(s)
  Naoko Yagishita, et al.
- Journal Title
  
  J.Biol.Chem 280
  
  Pages: 7909-7916
- Data Source
  KAKENHI-PROJECT-17659304
[Journal Article] Essential Role of Synoviolin in Embryogenesis2005
- Author(s)
  Naoko Yagishita, et al.
- Journal Title
  
  J. Biol. Chem. 280
  
  Pages: 7909-7916
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390290
[Journal Article] Essential Role of Synoviolin in Embryogenesis2005
- Author(s)
  Naoko Yagishita et al.
- Journal Title
  
  J Biol Chem 280
  
  Pages: 7909-7916
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591058
[Journal Article] Essential role of synoviolin in embryogenesis.2004
- Author(s)
  八木下尚子, et al.
- Journal Title
  
  J Biol Chem. (In press)(Epub ahead of print)
- Data Source
  KAKENHI-PROJECT-16390290
[Presentation] HTLV-1関連脊髄症におけるウイルス感染細胞に起因した神経障害機構の解析2023
- Author(s)
  新谷奈津美, 山岸誠, 清原和裕, 浅原尚美, 中島誠, 荒谷聡子, 八木下尚子, 内丸薫, 佐藤知雄, 山野嘉久.
- Organizer
  第27回日本神経感染症学会総会・学術大会
- Data Source
  KAKENHI-PROJECT-21K07427
[Presentation] 難病レジストリ研究の運用構築支援とデータシェアリング推進（難病プラットフォーム活動報告）2023
- Author(s)
  山口泉, 八木下尚子, 古澤嘉彦, 丹澤和雅, 長﨑正朗, 山野嘉久, 松田文彦.
- Organizer
  第27回日本医療情報学会春季学術大会
- Data Source
  KAKENHI-PROJECT-21K07427
[Presentation] HTLV-1感染細胞に起因したHAMの神経障害機構2023
- Author(s)
  新谷奈津美, 山岸誠, 清原和裕, 浅原尚美, 中島誠, 荒谷聡子, 八木下尚子, 内丸薫, 佐藤知雄, 山野嘉久.
- Organizer
  第9回日本HTLV-1学会学術集会
- Data Source
  KAKENHI-PROJECT-21K07427
[Presentation] HTLV-1 感染者のオンライン相談に関する意向調査2023
- Author(s)
  堀部恵梨佳, 相良康子, 佐藤知雄, 八木下尚子, 渡邉俊樹, 山野嘉久.
- Organizer
  第9回日本HTLV-1学会学術集会
- Data Source
  KAKENHI-PROJECT-21K07427
[Presentation] HTLV-1 キャリア電話相談の利用状況報告2023
- Author(s)
  堀部恵梨佳, 相良康子, 佐藤知雄, 八木下尚子, 渡邉俊樹, 山野嘉久.
- Organizer
  第9回日本HTLV-1学会学術集会
- Data Source
  KAKENHI-PROJECT-21K07427
[Presentation] HAMにおけるHTLV-1感染細胞に対するEZH1/2二重阻害剤の増殖抑制効果2023
- Author(s)
  小関昭仁, 新谷奈津美, 山岸誠, 山内淳司, 八木下尚子, 鷹尾直誠, 高橋克典, 國友康夫, 本間大輔, 荒木一司, 内丸薫, 佐藤知雄, 山野嘉久.
- Organizer
  第9回日本HTLV-1学会学術集会
- Data Source
  KAKENHI-PROJECT-21K07427
[Presentation] EZH1/2二重阻害剤はHTLV-1関連脊髄症におけるHTLV-1感染細胞の増殖と過剰免疫応答を抑制する2023
- Author(s)
  小関昭仁, 新谷奈津美, 山岸誠, 山内淳司, 八木下尚子, 本間大輔, 荒木一司, 内丸薫, 佐藤知雄, 山野嘉久.
- Organizer
  第27回日本神経感染症学会総会・学術大会
- Data Source
  KAKENHI-PROJECT-21K07427
[Presentation] A randomized controlled trial on corticosteroid therapy for HTLV-1-associated myelopathy/tropical spastic paraparesis in Japan (HAMLET-P trial).2022
- Author(s)
  Yamauchi J, Sato T, Yagishita N, Araya N, Nakagawa M, Matsuura E, Tsuboi Y, Tamaki K, Sakima H, Ishihara S, Araujo A, Jacobson S, Grassi MFR, Galvao-Castro B, Bland M, Taylor GP, Martin F, Yamano Y.
- Organizer
  20th International Conference on Human Retrovirology: HTLV and Related Viruses(HTLV22)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07427
[Presentation] Evaluation of quantification method of HTLV-1 proviral load in white blood cells using whole blood.2022
- Author(s)
  Sato T, Yagishita N, Araya N, Yamauchi J, Takahashi K, Kunitomo Y, Hasegawa Y, Higashikuse Y, Miyachi K, Yamano Y.
- Organizer
  20th International Conference on Human Retrovirology: HTLV and Related Viruses(HTLV22)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07427
[Presentation] HTLV-1 関連脊髄症(HAM)の神経障害機構の解析.2022
- Author(s)
  新谷奈津美, 荒谷聡子, 八木下尚子, 山内淳司, 鷹尾直誠, 佐藤知雄, 山野嘉久.
- Organizer
  第8回日本HTLV-1学会学術集会
- Data Source
  KAKENHI-PROJECT-21K07427
[Presentation] HTLV-1陽性臓器移植の診療に関する全国調査.2022
- Author(s)
  山内淳司、新谷奈津美、八木下尚子、佐藤知雄、湯沢賢治、山野嘉久.
- Organizer
  第55回日本臨床腎移植学会
- Data Source
  KAKENHI-PROJECT-21K07427
[Presentation] HTLV-1関連脊髄症（HAM）の病態形成機構.2022
- Author(s)
  新谷奈津美, 荒谷聡子, 八木下尚子, 山内淳司, 佐藤知雄, 山野嘉久.
- Organizer
  第63回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-21K07427
[Presentation] HAMの排尿障害における臨床症状評価と治療効果判定の標準化スケールの確立.2022
- Author(s)
  鷹尾直誠, 佐藤知雄, 山内淳司, 八木下尚子, 新谷奈津美, 荒谷聡子, 山野嘉久.
- Organizer
  第８回日本HTLV-1学会学術集会
- Data Source
  KAKENHI-PROJECT-21K07427
[Presentation] HTLV-1関連脊髄症（HAM）における神経障害機構の解析.2021
- Author(s)
  新谷奈津美、荒谷聡子、八木下尚子、山内淳司、佐藤知雄、山野嘉久.
- Organizer
  第7回日本HTLV-1学会学術集会
- Data Source
  KAKENHI-PROJECT-21K07427
[Presentation] HTLV-1陽性の臓器移植に関する全国アンケート調査.2021
- Author(s)
  山内淳司、新谷奈津美、八木下尚子、佐藤知雄、湯沢賢治、山野嘉久.
- Organizer
  第7回日本HTLV-1学会学術集会
- Data Source
  KAKENHI-PROJECT-21K07427
[Presentation] 全血を用いた改変HTLV-1プロウイルス量定量法に関する検討.2021
- Author(s)
  佐藤知雄、八木下尚子、新谷奈津美、荒谷聡子、山内淳司、高橋克典、國友康夫、長谷川由美子、東久世裕太、宮地恵子、佐藤賢文、直亨則、斎藤益満、山野嘉久.
- Organizer
  第7回日本HTLV-1学会学術集会
- Data Source
  KAKENHI-PROJECT-21K07427
[Presentation] HTLV-1による神経障害機構.2021
- Author(s)
  新谷奈津美, 荒谷聡子, 八木下尚子, 山内淳司, 佐藤知雄, 山野嘉久.
- Organizer
  第25回日本神経感染症学会総会・学術大会
- Data Source
  KAKENHI-PROJECT-21K07427
[Presentation] HTLV-1関連脊髄症（HAM)の神経障害機構.2021
- Author(s)
  新谷奈津美, 荒谷聡子, 八木下尚子, 山内淳司, 佐藤知雄, 山野嘉久.
- Organizer
  第62回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-21K07427
[Presentation] リアルワールドデータにより示されたHAMの排尿障害に対するミラベグロンの有用性.2021
- Author(s)
  飯島直樹, 山内淳司, 八木下尚子, 新谷奈津美, 荒谷聡子, 田辺健一郎, 佐藤知雄, 高田礼子, 山野嘉久.
- Organizer
  第62回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-21K07427
[Presentation] リアルワールドデータにより示されたHAMの排尿障害に対するミラベグロンの有用性.2021
- Author(s)
  飯島直樹, 山内淳司, 髙梨世子, 太刀川慶史, 八木下尚子, 新谷奈津美, 荒谷聡子, 田辺健一郎,　佐藤知雄, 高田礼子, 山野嘉久.
- Organizer
  第7回日本HTLV-1学会学術集会
- Data Source
  KAKENHI-PROJECT-21K07427
[Presentation] HTLV-1関連脊髄症のヒストリカルコントロールとして利用可能な病歴データの収集分析.2019
- Author(s)
  佐藤知雄、八木下尚子、山内淳司、堤俊太郎、新谷奈津美、井上永介、高田礼子、山野嘉久.
- Organizer
  第37回日本神経治療学会学術集会
- Data Source
  KAKENHI-PROJECT-17K08675
[Presentation] An Integarative Platform for Rare Diseases Research of Japan.2019
- Author(s)
  Furusawa Y, Yamaguchi I, Yagishita N, Tanzawa K, Kamatani Y, Natsukawa M, Takahashi Y, Kosugi S, Yamano Y, Matsuda F.
- Organizer
  第60回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-17K08675
[Presentation] HAM患者レジストリより収集分析されたHAM患者のリアルワールドデータ.2019
- Author(s)
  佐藤知雄、八木下尚子、山内淳司、堤俊太郎、新谷奈津美、井上永介、高田礼子、山野嘉久.
- Organizer
  第31回日本神経免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-17K08675
[Presentation] HAM診療ガイドライン2019策定のための患者の関心・価値観にかかわる調査.2019
- Author(s)
  八木下尚子, 高橋克典, 山内淳司, 佐藤知雄, 山野嘉久.
- Organizer
  第6回日本HTLV-1学会学術集会
- Data Source
  KAKENHI-PROJECT-17K08675
[Presentation] HAM診療ガイドライン策定のための患者の関心・価値観にかかわる調査2019
- Author(s)
  八木下尚子, 山内淳司, 佐藤知雄,山野嘉久
- Organizer
  第37回日本神経治療学会学術集会
- Data Source
  KAKENHI-PROJECT-17K08675
[Presentation] HTLV-1関連脊髄症（HAM）の新たな運動障害重症度評価指標の提案2017
- Author(s)
  八木下尚子、佐藤知雄、長谷川大輔、新谷奈津美、井上永介、高田礼子、山野嘉久
- Organizer
  日本HTLV-1学会
- Data Source
  KAKENHI-PROJECT-16H05157
[Presentation] リウマチ発症因子シノビオリンによる新規エネルギー代謝機構の解明。2016
- Author(s)
  藤田英俊、荒谷聡子、八木下尚子、山野嘉久、須藤カツ子、内野博之、西岡久寿樹、中島利博
- Organizer
  第 3 回 JCR ベーシックリサーチカンファレンス
- Place of Presentation
  アキバホール（東京　千代田区）
- Year and Date
  2016-10-14
- Data Source
  KAKENHI-PROJECT-16H05157
[Presentation] 関節リウマチにおける転写後修飾による多重化シグナル調節機構の解析。2016
- Author(s)
  荒谷聡子、藤田英俊、八木下尚子*、山野嘉久*、西岡久寿樹、中島利博
- Organizer
  第 3 回 JCR ベーシックリサーチカンファレンス
- Place of Presentation
  （アキバホール）東京都千代田区
- Year and Date
  2016-10-14
- Data Source
  KAKENHI-PROJECT-26461478
[Presentation] 関節リウマチにおける転写後修飾による多重化シグナル調節機構の解析。2016
- Author(s)
  荒谷聡子、藤田英俊、八木下尚子、山野嘉久、西岡久寿樹、中島利博
- Organizer
  第 3 回 JCR ベーシックリサーチカンファレンス
- Place of Presentation
  アキバホール（東京　千代田区）
- Year and Date
  2016-10-14
- Data Source
  KAKENHI-PROJECT-16H05157
[Presentation] E3 Ubiquitin ligase synoviolin inhibitors has effects on obesity2016
- Author(s)
  Aratani S, Fujita H, Yagishita N*, Yokota M, Nishioka K, Nakajima T
- Organizer
  International Conference on Obesity and Chronic Diseases (ICOCD-2016)
- Place of Presentation
  Las Vegas(USA)
- Year and Date
  2016-07-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461478
[Presentation] E3 Ubiquitin ligase synoviolin inhibitors has effects on obesity.2016
- Author(s)
  Aratani S, Fujita H, Yagishita N*, Yokota M, Nishioka K, Nakajima T
- Organizer
  International Conference on Obesity and Chronic Diseases(WCC 2016)
- Place of Presentation
  Las Vegas(USA)
- Year and Date
  2016-07-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05157
[Presentation] シノビオリン阻害剤の実用化に向けて。2016
- Author(s)
  荒谷聡子、藤田英俊、八木下尚子*、中島若巳、西岡久寿樹、中島利博
- Organizer
  第 5 回医薬工 3 大学包括連携推進シンポジウム
- Place of Presentation
  (東京医科大学病院）東京都新宿区
- Year and Date
  2016-06-18
- Data Source
  KAKENHI-PROJECT-26461478
[Presentation] リウマチ発症因子シノビオリンによる新規エネルギー代謝機構の解明。2016
- Author(s)
  藤田英俊、荒谷聡子、八木下尚子*、山野嘉久*、須藤カツ子*、内野博之、西岡久寿樹、中島利博
- Organizer
  第 3 回 JCR ベーシックリサーチカンファレンス
- Place of Presentation
  （アキバホール）東京都千代田区
- Year and Date
  2016-10-14
- Data Source
  KAKENHI-PROJECT-26461478
[Presentation] 線維筋痛症における疼痛シグナル解析モデルの構築2012
- Author(s)
  荒谷聡子、臼井千恵、八木下尚子、西岡健弥、山野嘉久、藤田英俊、伊藤健司、長田賢一、中村郁朗、岡寛、西岡久寿樹、中島利博
- Organizer
  日本線維筋痛症学会第4回学術集会
- Place of Presentation
  長崎(長崎ブリックホール)
- Data Source
  KAKENHI-PROJECT-23659502
[Presentation] 線維筋痛症患者における抗VGKC 複合体抗体の測定2012
- Author(s)
  山野嘉久、渡邉修、荒谷聡子、八木下尚子、藤田英俊、臼井千恵、西岡健弥、伊藤健司、長田賢一、中村郁朗、岡寛、中島利博、西岡久寿樹
- Organizer
  日本線維筋痛症学会第4回学術集会
- Place of Presentation
  長崎(長崎ブリックホール)
- Data Source
  KAKENHI-PROJECT-23659502
[Presentation] 線維筋痛症研究プラットフォームの確立と疼痛シグナル解析モデルの構築2012
- Author(s)
  中島利博、荒谷聡子、臼井千恵、八木下尚子、西岡健弥、山野嘉久、藤田英俊、伊藤健司、長田賢一、中村郁朗、岡寛、西岡久寿樹
- Organizer
  日本線維筋痛症学会第4回学術集会
- Place of Presentation
  長崎(長崎ブリックホール)
- Data Source
  KAKENHI-PROJECT-23659502
[Presentation] ER stress signaling as a chronic inflammation2011
- Author(s)
  Yagishita N, Aratani S, Yamano Y, Nishioka K, Nakajima T
- Organizer
  2nd Tokyo-Shanghai Workshop on Rheumatology 2011
- Place of Presentation
  Tokyo, Japan (Hilton Tokyo Bay Hotel)
- Year and Date
  2011-11-13
- Data Source
  KAKENHI-PROJECT-23659502
[Presentation] Importance of E3 ubiquitin ligase Synoviolin in fibrogenesis. Bio-Rheumatology International Congress (BRIC) Tokyo2011
- Author(s)
  Yagishita N, Hasegawa D, Aratani S, Yamano Y, Nakajima T
- Organizer
  The 8th GARN Meeting
- Place of Presentation
  Tokyo, Japan (Hilton Tokyo Bay Hotel)
- Year and Date
  2011-11-15
- Data Source
  KAKENHI-PROJECT-23659502
[Presentation] ER stress signaling as a chronic inflammation2011
- Author(s)
  Yagishita N, et al
- Organizer
  2nd Tokyo-Shanghai Workshop on Rheumatology 2011
- Place of Presentation
  Tokyo, Japan (Hilton Tokyo Bay Hotel)
- Year and Date
  2011-11-13
- Data Source
  KAKENHI-PROJECT-20689019
[Presentation] ER stress signaling as a chronic inflammation2011
- Author(s)
  Yagishita N, etal.
- Organizer
  2nd Tokyo-Shanghai Workshop on Rheumatology 2011(招待講演)
- Place of Presentation
  Tokyo, Japan (Hilron Tokyo Bay Hotel)
- Data Source
  KAKENHI-PROJECT-23659502
[Presentation] Importance of E3 ubiquitin ligase Synoviolin in fibrogenesis.2011
- Author(s)
  Yagishita N, etal.
- Organizer
  The 2011 ACR/ARHP Annual Scientific Meeting
- Place of Presentation
  Chicago, USA
- Data Source
  KAKENHI-PROJECT-23659502
[Presentation] Importance of E3 ubiquitin ligase Synoviolin in fibrogenesis2011
- Author(s)
  Yagishita N, Hasegawa D, Aratani S, Yamano Y, Nakajima T
- Organizer
  The 2011 ACR/ARHP Annual Scientific Meeting
- Place of Presentation
  Chicago, U.S.A.
- Year and Date
  2011-11-08
- Data Source
  KAKENHI-PROJECT-23659502
[Presentation] Importance of E3 ubiquitin ligase Synoviolin in fibrogenesis2011
- Author(s)
  Yagishita N, et al
- Organizer
  The 2011 ACR/ARHP Annual Scientific Meeting
- Place of Presentation
  Chicago, U.S.A.
- Year and Date
  2011-11-08
- Data Source
  KAKENHI-PROJECT-20689019
[Presentation] ER stress signaling as a chronic inflammation2011
- Author(s)
  Yagishita N, Aratani S, Yamano Y, Nishioka K, Nakajima T
- Organizer
  2nd Tokyo-Shanghai Workshop on Rheumatology 2011
- Place of Presentation
  Tokyo, Japan.(Hilton Tokyo Bay Hotel)
- Year and Date
  2011-11-13
- Data Source
  KAKENHI-PROJECT-20689019
[Presentation] シノビオリンから見た関節リウマチの病態研究2011
- Author(s)
  八木下尚子、中島利博
- Organizer
  第55回日本リウマチ学会総会・学術集会カレントシンポジウム「若手研究者が語るリウマチ性疾患の病態とシグナル伝達」
- Place of Presentation
  神戸(神戸ポートピアホテル神戸国際会議場)
- Year and Date
  2011-07-18
- Data Source
  KAKENHI-PROJECT-23659502
[Presentation] E3ユビキチンリガーゼシノビオリンの線維化への関与2011
- Author(s)
  八木下尚子、荒谷聡子、佐藤知雄、藤井亮爾、山野嘉久、西岡久寿樹、中島利博
- Organizer
  第55回日本リウマチ学会総会・学術集会
- Place of Presentation
  神戸(神戸ポートピアホテル神戸国際会議場神戸国際展示場)
- Year and Date
  2011-07-18
- Data Source
  KAKENHI-PROJECT-20689019
[Presentation] Importance of E3 ubiquitin ligase Synoviolin in fibrogenesis2011
- Author(s)
  Yagishita N, Hasegawa D, Aratani S, Yamano Y, Nakajima T
- Organizer
  The 2011 ACR/ARHP Annual Scientific Meeting
- Place of Presentation
  Chicago, U. S. A
- Year and Date
  2011-11-08
- Data Source
  KAKENHI-PROJECT-20689019
[Presentation] Importance of E3 ubiquitin ligase Synoviolin in fibrogenesis2011
- Author(s)
  Yagishita N, et al
- Organizer
  Bio-Rheumatology International Congress (BRIC) Tokyo : The 8th GARN Meeting
- Place of Presentation
  Tokyo, Japan (Hilton Tokyo Bay Hotel)
- Year and Date
  2011-11-15
- Data Source
  KAKENHI-PROJECT-20689019
[Presentation] シノビオリンから見た関節リウマチの病態研究2011
- Author(s)
  八木下尚子、中島利博
- Organizer
  第55回日本リウマチ学会カレントシンポジウム「若手研究者が語るリウマチ性疾患の病態とシグナル伝達」
- Place of Presentation
  神戸(神戸ポートピアホテル神戸国際会議場神戸国際展示場)
- Year and Date
  2011-07-18
- Data Source
  KAKENHI-PROJECT-20689019
[Presentation] E3 ubiquitin ligase Synoviolin is involved in liver fibrogenesis2011
- Author(s)
  Aratani S, Yagishita N, Hasegawa D, Nishioka K, Nakajima T
- Organizer
  UbiquitinDrug Discovery andDiagnostics
- Place of Presentation
  Philadelphia, U. S. A
- Year and Date
  2011-07-12
- Data Source
  KAKENHI-PROJECT-20249052
[Presentation] ER stress signaling as a chronicity of imflammation2011
- Author(s)
  Yagishita N, Aratani S, Yamano Y, Nishioka K, Nakajima T
- Organizer
  2nd Tokyo-Shanghai Rheumatology Workshop
- Place of Presentation
  Tokyo, Japan(Hilton Tokyo Bay Hotel)
- Year and Date
  2011-11-13
- Data Source
  KAKENHI-PROJECT-20249052
[Presentation] Importance of E3 ubiquitin ligase Synoviolin in fibrogenesis2011
- Author(s)
  Yagishita N, etal.
- Organizer
  Bio-Rheumatology International Congress (BRIC) Tokyo:The 8th GARN Meeting(招待講演)
- Place of Presentation
  Tokyo, Japan (Hilron Tokyo Bay Hotel)
- Data Source
  KAKENHI-PROJECT-23659502
[Presentation] シノビオリンから見た関節リウマチの病態研究2011
- Author(s)
  八木下尚子、他1名
- Organizer
  第55回日本リウマチ学会総会・学術集会カレントシンポジウム「若手研究者が語るリウマチ性疾患の病態とシグナル伝達」(招待講演)
- Place of Presentation
  神戸(神戸ポートピアホテル神戸国際会議場神戸国際展示場)
- Data Source
  KAKENHI-PROJECT-23659502
[Presentation] Importance of E3 ubiquitin ligase Synoviolin in fibrogenesis. Bio-Rheumatology International Congress(BRIC) Tokyo2011
- Author(s)
  Yagishita N, Hasegawa D, Aratani S, Yamano Y, Nakajima T
- Organizer
  The 8th GARN Meeting
- Place of Presentation
  Tokyo, Japan.(Hilton Tokyo Bay Hotel)
- Year and Date
  2011-11-15
- Data Source
  KAKENHI-PROJECT-20689019
[Presentation] Importance of E3 ubiquitin ligase Synoviolin in fibrogenesis2011
- Author(s)
  Yagishita N, Hasegawa D, Aratani S, Yamano Y, Nakajima T
- Organizer
  The 2011 ACR/ARHP Annual Scientific Meeting
- Place of Presentation
  Chicago, U. S. A
- Year and Date
  2011-11-08
- Data Source
  KAKENHI-PROJECT-20249052
[Presentation] E3ユビキチンリガーゼシノビオリンの線維化への関与2011
- Author(s)
  八木下尚子、他6名
- Organizer
  第55回日本リウマチ学会総会・学術集会
- Place of Presentation
  神戸(神戸ポートピアホテル神戸国際会議場神戸国際展示場)
- Data Source
  KAKENHI-PROJECT-23659502
[Presentation] Synoviolin ; a novel regulator for fibrosis2011
- Author(s)
  Aratani S, Yagishita N, Hasegawa D, Nishioka K, Nakajima T
- Organizer
  Ubiquitin Drug Discovery and Diagnostics
- Place of Presentation
  Philadelphia, U. S. A
- Year and Date
  2011-07-12
- Data Source
  KAKENHI-PROJECT-20249052
[Presentation] E3 ユビキチンリガ-ゼシノビオリンの線維化への関与2011
- Author(s)
  八木下尚子、荒谷聡子、佐藤知雄、藤井亮爾、山野嘉久、西岡久寿樹、中島利博
- Organizer
  第55回日本リウマチ学会総会・学術集会
- Place of Presentation
  神戸(神戸ポートピアホテル神戸国際会議場)
- Year and Date
  2011-07-18
- Data Source
  KAKENHI-PROJECT-23659502
[Presentation] 肝線維化における E3 ユビキチリンリガーゼシノビオリンの関与国際科学振興財団フォーラム分子消化器病学研究会2010
- Author(s)
  長谷川大輔、松本伸行、八木下尚子、荒谷聡子、山野嘉久、西岡久寿樹、中島利博、伊東文生
- Organizer
  第18回浜名湖シンポジウム
- Place of Presentation
  浜名湖
- Data Source
  KAKENHI-PROJECT-20249052
[Presentation] The role of E3 ubiquitin ligase Synoviolin in bone destruction of rheumatoid arthritis.
- Author(s)
  Yagishita N, Aratani S, Fujita H, Yamano Y, Nishioka K, Nakajima T.
- Organizer
  第58回日本リウマチ学会総会・学術集会
- Place of Presentation
  東京都（港区）〔グランドプリンスホテル新高輪〕
- Year and Date
  2014-04-24 – 2014-04-26
- Data Source
  KAKENHI-PROJECT-26461478
[Presentation] The functions of the post-translational modifications in rheumatoid arthritis
- Author(s)
  Aratani S, Yagishita N, Kanazawa T, Nakajima F, Yamano Y, Nishioka K, Nakajima T
- Organizer
  1st Bio-Rheumatology International Congress(BRIC) Tokyo/The 8th GARN Meeting
- Place of Presentation
  Tokyo, Japan(Hilton Tokyo Bay Hotel)
- Data Source
  KAKENHI-PROJECT-20249052
[Presentation] Importance of E3 ubiquitin ligase Synoviolin in fibrogenesis
- Author(s)
  Yagishita N, Hasegawa D, Aratani S, Yamano Y, Nakajima T
- Organizer
  1st Bio-Rheumatology International Congress(BRIC) Tokyo/The 8th GARN Meeting
- Place of Presentation
  Tokyo, Japan(Hilton Tokyo Bay Hotel)
- Data Source
  KAKENHI-PROJECT-20249052

1. NAKAJIMA Toshihiro (90260752)

# of Collaborated Projects: 10 results

# of Collaborated Products: 55 results
2. ARATANI Satoko (40387064)

# of Collaborated Projects: 6 results

# of Collaborated Products: 33 results
3. YAMANO Yoshihisa (80445882)

# of Collaborated Projects: 3 results

# of Collaborated Products: 23 results
4. MARUYAMA Ikuro (20082282)

# of Collaborated Projects: 3 results

# of Collaborated Products: 11 results
5. OKADA Hidechika (30160683)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. AKATSU Hiroyasu (00399734)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
7. 藤田英俊 (90571802)

# of Collaborated Projects: 3 results

# of Collaborated Products: 12 results
8. KAWAHARA Koichi (10381170)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
9. 山崎聡士 (30367388)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. HIGUCHI Ituro (80183573)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. KAMI Masahiro (50422423)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
12. NISHIOKA Kusuki (60049070)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 三浦直樹 (80508036)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 外波弘之 (90420405)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 伊藤隆史 (20381171)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. SATO Tomoo

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
17. ARAYA Natsumi

# of Collaborated Projects: 0 results

# of Collaborated Products: 5 results
18. 山岸誠

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 中村裕之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Yagishita Naoko 八木下 尚子

八木下 尚子 ヤギシタ ナオコ

YAGISHITA Naoko 八木下 尚子

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HAMの新規発症機序としてのプロウイルス挿入による宿主遺伝子発現のシス攪乱の解明Principal Investigator

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Elucidation of a novel mechanism of HAM pathogenesis by targeting the innate immune systemPrincipal Investigator

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The study of physiological mechanisms of rheumatoid synovial cells by SynoviolinPrincipal Investigator

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The study of bone destruction mechanism of rheumatoid arthritis by synoviolinPrincipal Investigator

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Synoviolin inhibitors for treatment of fibrosisPrincipal Investigator

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関節リウマチと骨粗鬆症の接点をなす分子複合体の機能解析Principal Investigator

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The transcriptional regulation of Synoviolin in rheumatoid synovial cells.Principal Investigator

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The research of rheumatoid arthritis from aspect of developmental biology.Principal Investigator

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Yagishita Naoko 八木下尚子

八木下尚子ヤギシタナオコ

YAGISHITA Naoko 八木下尚子

[Book] New Developments in the Pathogenesis of Rheumatoid Arthritis　Synoviolin is a novel pathogenic factor of arthropathy and chronic inflammation.2016