Yamauchi Toshimasa 山内敏正

… Alternative Names

YAMAUCHI Toshimasa 山内敏正

Less

Researcher Number	40372370
Other IDs
Affiliation (Current)	2025: 東京大学, 医学部附属病院, 教授
Affiliation (based on the past Project Information) *help	2018 – 2024: 東京大学, 医学部附属病院, 教授 2014 – 2017: 東京大学, 医学部附属病院, 准教授 2014: 東京大学, 大学院医学系研究科, 特任准教授 2012: 東京大学, 医学部附属病院, 講師 2011: The University of Tokyo, 医学部附属病院, その他 … More 2010: The University of Tokyo, 医学部附属病院, 講師 2009: 東京大学, 医学部附属病院, 准教授 2007 – 2009: The University of Tokyo, 医学部附属病院, 特任准教授 2007 – 2008: The University of Tokyo, Faculty of Medicine, Project Associate Professor 2007: The University of Tokyo, Faculty of Medicine, Project Associate Professor 2007: The University of Tokyo, Faculty of Medicine, Visiting Associate Professor 2006: 東京大学, 医学部付属病院, 客員助教授 2006: 東京大学, 医学部附属病院, 客員教員 2005 – 2006: The University of Tokyo, Faculty of Medicine, Visiting Associate Professor, 医学部附属病院, 客員助教授 2004 – 2006: The University of Tokyo, Faculty of Medicine, Visiting Assistant Professor, 医学部附属病院, 寄附講座教員(客員助教授) 2005: 東京大学, 医学部付属病院, 特任助教授 2004 – 2005: 東京大学, 医学部附属病院, 寄付講座教員(客員助教授) 2004: 東京大学, 医学部・附属病院, 寄付講座教員(客員助教授) 2004: University of Tokyo Hospital, Department of Metabolic Diseases, Special Associate Professor, 医学部附属病院糖尿病・代謝内科, 客員助教授 2003: the University of Tokyo, faculty of Medicine, Research Associate, 医学部附属病院, 助手 Less
Review Section/Research Field	Principal Investigator Metabolomics / Biological Sciences / Medium-sized Section 54:Internal medicine of the bio-information integration and related fields / Biological Sciences Except Principal Investigator Metabolomics / Basic Section 59040:Nutrition science and health science-related / Biological Sciences / Medium-sized Section 58:Society medicine, nursing, and related fields / Medium-sized Section 54:Internal medicine of the bio-information integration and related fields / Metabolomics / Biological Sciences / Biological Sciences / Orthopaedic surgery
Keywords	Principal Investigator 糖尿病 / アディポネクチン / アディポカイン / Stra13 / IRS-2 / IRS-1 / diabetes / CBP / 脂質代謝 / 糖代謝 … More / AdipoR / インスリン / 動脈硬化 / 肥満 / 受容体 / PPAR / AMPキナーゼ / インスリン抵抗性 / 遺伝因子機能解析 / ゲノム / 発生・分化 / 老化 / promoter / adipokine / プロモーター / exocytosis / adiponectin / glucokinase / high-fat diet / pancreatic beta-cells / 開口放出 / グルコキナーゼ / 高脂肪食 / 膵β細胞 / physiological activity / microarray / genes / applied animal / アディポネクチン受容体 / レプチン / PPARγ / 遺伝子欠損マウス / 生理活性 / マイクロアレイ / 遺伝子 / 応用動物 / 食品 / 脂質 / シグナル伝達 / 細菌 / エネルギー代謝 / 脂肪細胞 / 転写因子 / シグナル情報伝達 / アゴニスト / 好中球エラスターゼ … More Except Principal Investigator 糖尿病 / アディポネクチン / 肥満 / diabetes / アディポネクチン受容体 / PPAR / インスリン抵抗性 / PPARγ / アディポカイン / AMP kinase / obesity / AMPキナーゼ / adiponectin / 動脈硬化 / 脂肪細胞 / 糖代謝 / 受容体 / 遺伝子 / receptor / adipokine / IRS-2 / SREBP-1c / insulin resistance / レプチン / 糖取り込み / SNP / 健康長寿 / AdipoR / インスリン / シグナル伝達 / 遺伝子欠損マウス / NAFLD / 生活習慣病 / デバイス / ドレッシング / 振動 / 人工知能 / 低周波振動 / スマートドレッシング / 看護理工学 / 難治性潰瘍 / 糖尿病足潰瘍 / 局所低周波振動 / ドレッシング材 / 転写因子 / 脂肪組織 / 褐色脂肪細胞 / 糖尿病合併症 / 認知症 / 生体機能利用 / 農林水産物 / 食品 / トランスレーショナルリサーチ / 薬理学 / fat cell / insulin / signal transduction / gene / gene targeting / Diabetes / glucokinase / high-fat diet / insulin secretion / islet triglyceride content / DNA microarray / グルコキナーゼ / 高脂肪食 / インスリン分泌 / 中性脂肪含量 / metabolic syndrome / atherosclerosis / adipocyte / insulin receptor substrate / insulin receptor / レプチン抵抗性改善薬 / 代謝症候群 / インスリン受容体基質 / インスリン受容体 / nuclear receptors / glucose uptake / fatty acid oxidation / adiponectin resistance / adiponectin receptors / 脂質代謝異常 / 核内受容体型転写因子 / 脂肪酸燃焼 / アディポネクチン抵抗性 / affected sib pair / Haplotype / 一塩基多型 / 全ゲノムスキャン / 罹患同胞対法 / 個人情報匿名化 / 2型糖尿病 / 連鎖不平衡 / 相関解析 / 罹患同胞対 / ハプロタイプ / 生体分子医学 / 細胞内シグナル伝達 / エピゲノム / 転写 / 疾患感受性遺伝子 / 痩せ / 脂肪毒性 / 脂肪蓄積 / 食欲 / 脂質代謝 / 動脈硬化症 / 血管内皮細胞 / インスリン受容体基質-2 / 関節炎 / 骨代謝 / レジスチン / 脂質 / 糖 / 発言制御 / エネルギー浪費 / 組織特異的遺伝子改変動物 / DNAチップ / 転写共役因子 Less

新規アディポネクチン受容体結合タンパク質の機能解析と生活習慣病治療への応用
- Principal Investigator
  
  岩部真人
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Nippon Medical School
Diabetic Foot Ulcer Healing Enhancement Device via a Novel Glucose Metabolism Promoting Mechanism: A New Horizon of Wound Care Management
- Principal Investigator
  
  Nakagami Gojiro
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Pioneering)
- Review Section
  
  Medium-sized Section 58:Society medicine, nursing, and related fields
- Research Institution
  The University of Tokyo
Impact of NFIA in systemic metabolism and energy balance
- Principal Investigator
  
  脇裕典
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Akita University
  The University of Tokyo
New developments in basic and applied adiponectin research toward reduction of dementia risk and realization of healthy longevity
- Principal Investigator
  
  Kadowaki Takashi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 54:Internal medicine of the bio-information integration and related fields
- Research Institution
  The University of Tokyo
Elucidation of the cause of diabetes in the Japanese population using whole genome information and development of diagnostic and therapeutic methods using iPS cellsPrincipal Investigator
- Principal Investigator
  
  Yamauchi Toshimasa
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 54:Internal medicine of the bio-information integration and related fields
- Research Institution
  The University of Tokyo
The investigation and analysis for developing next-generation functional foods against lifestyle-related diseases
- Principal Investigator
  
  Iwabu Miki
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Metabolomics
- Research Institution
  The University of Tokyo
生活習慣病と組織幹細胞老化の連関メカニズム解明とその制御による予防・治療法の開発Principal Investigator
- Principal Investigator
  
  山内敏正
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
Pathophysiological roles of adipokines in the regulation of gut microbiota in life-style related diseasesPrincipal Investigator
- Principal Investigator
  
  YAMAUCHI TOSHIMASA
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Metabolomics
- Research Institution
  The University of Tokyo
Comprehensive and expansive research of the universal metabolic regulation mechanisms for healthspan
- Principal Investigator
  
  KADOWAKI Takashi, 門脇孝
- Project Period (FY)
  2014 – 2019
- Research Category
  
  Grant-in-Aid for Specially Promoted Research
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
Building and establishing platform technologies for Structure Based Drug Design targeting AdipoR
- Principal Investigator
  
  Iwabu Miki
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Metabolomics
- Research Institution
  The University of Tokyo
Regulation of lipid accumulation by new diabetes susceptible genes and the role of the epigenome
- Principal Investigator
  
  WAKI Hironori
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
運動模倣薬としてのアディポネクチン受容体活性化薬の開発Principal Investigator
- Principal Investigator
  
  山内敏正
- Project Period (FY)
  2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Metabolomics
- Research Institution
  The University of Tokyo
Molecular basis and disorders of control of appetite and fat accumulation
- Principal Investigator
  
  KANGAWA Kenji
- Project Period (FY)
  2010 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  National Cardiovascular Center Research Institute
新規転写因子・エピゲノムネットワークによる脂肪蓄積制御メカニズムの解明Principal Investigator
- Principal Investigator
  
  山内敏正
- Project Period (FY)
  2010 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
アディポネクチン/アディポネクチン受容体の増加・活性化剤の開発と成分同定Principal Investigator
- Principal Investigator
  
  山内敏正
- Project Period (FY)
  2009
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Metabolomics
- Research Institution
  The University of Tokyo
Integrated elucidation of metabolic pathway in the physiology and pathology
- Principal Investigator
  
  KADOWAKI Takashi
- Project Period (FY)
  2008 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Metabolomics
- Research Institution
  The University of Tokyo
Novel advances of adiponectin signal transduction networkPrincipal Investigator
- Principal Investigator
  
  YAMAUCHI Toshimasa
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Metabolomics
- Research Institution
  The University of Tokyo
The roles of insulin receptor substrate-2 in the regulation of glucosehomeostasis and atherosclerosis
- Principal Investigator
  
  KUBOTA Naoto
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  The University of Tokyo
アディポネクチン受容体アゴニストの植物からの探索と糖尿病の根本的治療薬・食品開発Principal Investigator
- Principal Investigator
  
  山内敏正
- Project Period (FY)
  2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Metabolomics
- Research Institution
  The University of Tokyo
脂質代謝調節因子レジスチンによる骨代謝調節機構の解明
- Principal Investigator
  
  中村耕三
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Orthopaedic surgery
- Research Institution
  The University of Tokyo
Physiological and pathophysiological roles ofAdiponectin receptors and identification of molecular targets for treatment of life-style related diseases
- Principal Investigator
  
  KADOWAKI Takashi
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Metabolomics
- Research Institution
  The University of Tokyo
Identification of transcription factor which regulates obesity-linked downregulation of adiponectin gene and development of treatment modality for metabolic syndromePrincipal Investigator
- Principal Investigator
  
  YAMAUCHI Toshimasa
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Metabolomics
- Research Institution
  The University of Tokyo
抗生活習慣病因子アディポネクチンの受容体アゴニスト・発現増加剤・切断活生化剤探索Principal Investigator
- Principal Investigator
  
  山内敏正
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Metabolomics
- Research Institution
  The University of Tokyo
肝臓におけるSTAT3/SOCS3経路の調節による新しい糖脂質代謝改善療法の開発
- Principal Investigator
  
  植木浩二郎
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Metabolomics
- Research Institution
  The University of Tokyo
Analysis of function and signal transduction pathway of resistin using genetically-engineered animals
- Principal Investigator
  
  TERAUCHI Yasuo
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Metabolomics
- Research Institution
  Yokohama City University
Physiological and pathophysiological roles and signal transduction of adiponectin receptors
- Principal Investigator
  
  KADOWAKI Takashi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Metabolomics
- Research Institution
  The University of Tokyo
Differentiation, proliferation, and function of pancreatic beta-cellsPrincipal Investigator
- Principal Investigator
  
  YAMAUCHI toshimasa
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Metabolomics
- Research Institution
  The University of Tokyo
CBPヘテロ欠損マウスを用いたレプチン非依存性の新規エネルギー・糖・脂質代謝調節経路の同定
- Principal Investigator
  
  KADOWAKI Takashi
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Metabolomics
- Research Institution
  The University of Tokyo
Physiological and pathophysiological roles of adiponectin and AdipoR1/R2Principal Investigator
- Principal Investigator
  
  YAMAUCHI Toshimasa, 寺内康夫
- Project Period (FY)
  2003 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
Mechanism of insulin resistance and strategy of treatment
- Principal Investigator
  
  TOBE Kazuyuki
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Metabolomics
- Research Institution
  the University of Tokyo
Analysis of molecular mechanisms for impaired insulin secretion and beta-cell hyperplasia caused by lipotoxicity
- Principal Investigator
  
  TERAUCHI Yasuo
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Metabolomics
- Research Institution
  The University of Tokyo
The pathophysiological roles of adiponectin in the regulation of type 2 diabetes, hyperlipidemia and atherosclerosis
- Principal Investigator
  
  KADOWAKI Takashi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Metabolomics
- Research Institution
  the University of Tokyo
Identification of type 2 diabetes susceptibility genes in the Japanese population by genome mapping and candidate gene approach and functional analysis
- Principal Investigator
  
  KADOWAKI Takashi
- Project Period (FY)
  2000 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  University of Tokyo

[Book] 月刊カレントテラピー2023
- Author(s)
  岩部　真人, 岩部　美紀, 山内　敏正
- Total Pages
  149
- Publisher
  ライフメディコム
- Data Source
  KAKENHI-PROJECT-23K24785
[Book] 月刊糖尿病2022
- Author(s)
  岩部　真人, 岩部　美紀, 山内　敏正
- Total Pages
  96
- Publisher
  医学出版
- Data Source
  KAKENHI-PROJECT-23K24785
[Book] 糖尿病診療update2022
- Author(s)
  岩部　美紀, 岩部　真人,　山内　敏正
- Total Pages
  186
- Publisher
  日本臨牀
- Data Source
  KAKENHI-PROJECT-23K24785
[Book] 生物の寿命延長：老化・長寿命の基盤研究最前線2022
- Author(s)
  岩部　美紀, 岩部　真人, 山内　敏正
- Total Pages
  460
- Publisher
  エヌ・ティー・エス
- Data Source
  KAKENHI-PROJECT-23K24785
[Book] 「糖尿病」という病名と糖尿病への偏見、「糖尿病プラクティス」2021
- Author(s)
  庄嶋伸浩、山内敏正
- Publisher
  医歯薬出版株式会社
- Data Source
  KAKENHI-PROJECT-18H04053
[Book] 「アディポネクチン受容体の新たな構造」糖尿病学20212021
- Author(s)
  岩部　美紀、岩部　真人、山内　敏正、門脇　孝
- Total Pages
  155
- Publisher
  株式会社　診断と治療社
- Data Source
  KAKENHI-PROJECT-19H01052
[Book] 「序文」糖尿病学20212021
- Author(s)
  門脇　孝、山内　敏正
- Total Pages
  155
- Publisher
  株式会社　診断と治療社
- Data Source
  KAKENHI-PROJECT-19H01052
[Book] 高齢者糖尿病治療ガイド20212021
- Author(s)
  山内敏正
- Publisher
  文光堂
- Data Source
  KAKENHI-PROJECT-18H04053
[Book] 知っておきたいことア・ラ・カルト　歌舞伎症候群」Medical Practice, 37巻12号2020
- Author(s)
  岩部　真人、岩部　美紀、山内　敏正
- Publisher
  文光堂
- Data Source
  KAKENHI-PROJECT-18H04053
[Book] 【糖尿病エキスパートブック】食事療法・栄養指導に活かす最新情報「インスリン抵抗性はどこまで解されたか」臨床栄養2020
- Author(s)
  岩部　真人、岩部　美紀、山内　敏正
- Publisher
  医歯薬出版株式会社
- Data Source
  KAKENHI-PROJECT-18H04053
[Book] 【高血糖毒性と組織障害】「脂肪組織」糖尿病2020
- Author(s)
  岩部　真人、岩部　美紀、山内　敏正
- Publisher
  一般社団法人日本糖尿病学会
- Data Source
  KAKENHI-PROJECT-18H04053
[Book] 【糖尿病診療update-最新の診断と治療-】「糖尿病治療薬に関する最近の話題　インスリン抵抗性改善薬　チアゾリジン薬」2020
- Author(s)
  岩部　真人、岩部　美紀、山内　敏正
- Publisher
  日本臨床社
- Data Source
  KAKENHI-PROJECT-18H04053
[Book] 高度肥満症のゲノムワイドポリジェニックリスクスコア.2020
- Author(s)
  庄嶋伸浩、鈴木顕、細江隼、山内敏正、門脇孝
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-18H04053
[Book] 内分泌・糖尿病・代謝内科糖尿病患者の薬剤効果予測に遺伝情報をどう活かすか2019
- Author(s)
  庄嶋伸浩、山内敏正、鈴木顕、細江準、門脇孝
- Pages
  206-213
- Total Pages
  78
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-26000012
[Book] 糖尿病・内分泌代謝科48巻：【臓器連関による代謝制御と生体機能調節】運動模倣シグナルによるエネルギー代謝調節メカニズム2019
- Author(s)
  岩部真人、岩部美紀、山内敏正、門脇孝
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-18H04053
[Book] 実験医学37巻：【臓器連環による生体恒常性の破綻と疾患】脂肪細胞産生分子がつなぐ臓器連環と動的恒常性。2019
- Author(s)
  岩部真人、岩部美紀、山内敏正、門脇孝
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-18H04053
[Book] CBT-OB肥満に対する認知行動療法マニュアル2019
- Author(s)
  リッカルド・ダッレ・グラーヴェ、マッシミリアーノ・サルティラーナ、マルワン・エル・ゴッチ、シモーナ・カルージ、吉内　一浩・山内　敏正監訳
- Total Pages
  266
- Publisher
  金子書房
- Data Source
  KAKENHI-PROJECT-18H04053
[Book] 免疫学：免疫・炎症病態×治療Update：第Ⅲ部免疫・炎症性疾患の病態の理解と治療への展開2019
- Author(s)
  岩部真人、山内敏正、岩部美紀、門脇孝
- Publisher
  南山堂
- Data Source
  KAKENHI-PROJECT-18H04053
[Book] 糖尿病・内分泌代謝科　第48巻第3号：糖尿病患者の薬剤効果予測に遺伝情報をどう活かすか2019
- Author(s)
  細江隼, 庄嶋伸浩, 鈴木顕、山内敏正, 門脇孝
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-18H04053
[Book] 「糖尿病学2019」：日本人集団における28の新規2型糖尿病感受性領域の同定2019
- Author(s)
  山内敏正
- Publisher
  診断と治療社
- Data Source
  KAKENHI-PROJECT-18H04053
[Book] 医学のあゆみ269巻：【AMPキナーゼと医学】肥満・糖尿病の創薬ターゲットとしてのAMPキナーゼ2019
- Author(s)
  岩部真人、岩部美紀、山内敏正、門脇孝
- Publisher
  医歯薬出版
- Data Source
  KAKENHI-PROJECT-18H04053
[Book] 動脈硬化診療のすべて：アディポサイエンス・高インスリン血症2019
- Author(s)
  山内敏正、庄嶋伸浩
- Publisher
  日本医師会
- Data Source
  KAKENHI-PROJECT-18H04053
[Book] 内分泌・糖尿病・代謝内科　糖尿病患者の薬剤効果予測に遺伝情報をどう活かすか2019
- Author(s)
  庄嶋　伸浩、山内　敏正、鈴木　顕、細江　準、門脇　孝
- Total Pages
  78
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-18H04053
[Book] 糖尿病・内分泌代謝科　第49巻第5号　：パスウェイ解析を用いた2型糖尿病遺伝素因の日欧の比較2019
- Author(s)
  細江隼, 庄嶋伸浩, 山内敏正, 門脇孝
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-18H04053
[Book] 糖尿病　62巻8号 6.インスリン受容体遺伝子異常と糖尿病2019
- Author(s)
  細江隼, 庄嶋伸浩, 山内敏正, 門脇孝
- Publisher
  一般社団法人　日本糖尿病学会
- Data Source
  KAKENHI-PROJECT-18H04053
[Book] 日本内科学雑誌管理が困難な糖尿病とその対策2018
- Author(s)
  門脇孝、山内敏正、鈴木亮
- Pages
  1810-1818
- Total Pages
  376
- Publisher
  日本内科学会
- Data Source
  KAKENHI-PROJECT-26000012
[Book] CLININCAL CALCIUM2017
- Author(s)
  岩部　美紀、山内　敏正、岩部　真人、門脇　孝
- Total Pages
  143
- Publisher
  医薬ジャーナル社
- ISBN
  9784753286270
- Data Source
  KAKENHI-PROJECT-16K15487
[Book] 動脈・静脈の疾患（下）日本臨床2017
- Author(s)
  岩部　美紀、山内　敏正、岩部　真人、門脇　孝
- Total Pages
  610
- Publisher
  日本臨牀社
- ISBN
- Data Source
  KAKENHI-PROJECT-16K15487
[Book] 糖尿病【肥満糖尿病克服への新たな挑戦】「アディポロンと健康長寿」2016
- Author(s)
  岩部　美紀、山内　敏正、門脇　孝
- Total Pages
  50
- Publisher
  一般社団法人日本糖尿病学会
- Data Source
  KAKENHI-PROJECT-16K15487
[Book] 内分泌・糖尿病・代謝内科【話題】「アディポロン」2016
- Author(s)
  岩部　美紀、山内　敏正、岩部　真人、門脇　孝
- Total Pages
  82
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-16K15487
[Book] 実験医学・【「解明」から「制御」へ　肥満症のメディカルサイエンス】（第1章）エネルギー代謝の制御機構　「アディポネクチンの生理機能　ー肥満・2型糖尿病治療に向けて」2016
- Author(s)
  岩部　美紀、山内　敏正、岩部　真人、門脇　孝
- Total Pages
  212
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-26293216
[Book] 内分泌・糖尿病・代謝内科「アディポネクチン受容体の構造」2016
- Author(s)
  岩部　美紀、山内　敏正、岩部　真人、門脇　孝
- Total Pages
  90
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-26293216
[Book] 糖尿病【肥満糖尿病克服への新たな挑戦】「アディポロンと健康長寿」2016
- Author(s)
  岩部　美紀、山内　敏正、門脇　孝
- Total Pages
  50
- Publisher
  一般社団法人日本糖尿病学会
- Data Source
  KAKENHI-PROJECT-26293216
[Book] Diabetes Frontier2016
- Author(s)
  山内　敏正、岩部　真人、細江　隼、門脇　孝
- Total Pages
  134
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PUBLICLY-15H01507
[Book] 内分泌・糖尿病・代謝内科【話題】「アディポロン」2016
- Author(s)
  岩部　美紀、山内　敏正、岩部　真人、門脇　孝
- Total Pages
  82
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-26293216
[Book] 内分泌・糖尿病・代謝内科「アディポネクチン受容体の構造」2016
- Author(s)
  岩部　美紀、山内　敏正、岩部　真人、門脇　孝
- Total Pages
  90
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-16K15487
[Book] Diabetes Frontier2016
- Author(s)
  山内　敏正、岩部　真人、細江　隼、門脇　孝
- Total Pages
  134
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-26253058
[Book] 日本臨牀・『新時代の臨床糖尿病学（上）』【VII糖尿病治療　薬物療法　新規糖尿病治療薬】「アディポネクチン受容体アゴニスト（アディポロン）」2015
- Author(s)
  岩部　美紀、山内　敏正、岩部　真人、門脇　孝
- Total Pages
  671
- Publisher
  日本臨床社
- Data Source
  KAKENHI-PROJECT-26293216
[Book] 糖尿病診療マスター2015
- Author(s)
  山内　敏正
- Total Pages
  992
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-26253058
[Book] 血管医学・【臓器の記憶と血管代謝ニッシェ】「アディポネクチン受容体機能低下に伴う臓器記憶の変容」2015
- Author(s)
  岩部美紀、山内敏正、岩部真人、門脇孝
- Total Pages
  118
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-26293216
[Book] 内分泌・糖尿病・代謝内科2015
- Author(s)
  山内　敏正
- Total Pages
  338
- Publisher
  科学評論社
- Data Source
  KAKENHI-PUBLICLY-15H01507
[Book] 内分泌・糖尿病・代謝内科2015
- Author(s)
  山内　敏正
- Total Pages
  338
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-26253058
[Book] 糖尿病診療マスター2015
- Author(s)
  山内　敏正
- Total Pages
  992
- Publisher
  医学書院
- Data Source
  KAKENHI-PUBLICLY-15H01507
[Book] DIABETES UPDATE2014
- Author(s)
  山内敏正、岩部美紀、岩部真人、門脇孝
- Total Pages
  3
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-26253058
[Book] 医学のあゆみ2014
- Author(s)
  山内敏正、門脇孝
- Total Pages
  6
- Publisher
  医歯薬出版
- Data Source
  KAKENHI-PROJECT-26253058
[Book] 医学のあゆみ2014
- Author(s)
  山内敏正
- Total Pages
  1
- Publisher
  医歯薬出版
- Data Source
  KAKENHI-PROJECT-26253058
[Book] BIO Clinica2014
- Author(s)
  山内敏正
- Total Pages
  5
- Publisher
  北隆館
- Data Source
  KAKENHI-PROJECT-26253058
[Book] 細胞【糖尿病治療の進歩】 AdipoRを標的とした健康長寿薬開発への挑戦2014
- Author(s)
  岩部　美紀、山内　敏正、門脇　孝
- Total Pages
  52
- Publisher
  ニューサイエンス社
- Data Source
  KAKENHI-PROJECT-26293216
[Book] Diabetes Journal2014
- Author(s)
  山内敏正、門脇孝
- Total Pages
  9
- Publisher
  南江堂
- Data Source
  KAKENHI-PROJECT-26253058
[Book] 細胞2014
- Author(s)
  山内敏正
- Total Pages
  3
- Publisher
  北隆館
- Data Source
  KAKENHI-PROJECT-26253058
[Book] 動脈硬化予防2014
- Author(s)
  山内敏正、門脇孝
- Total Pages
  8
- Publisher
  メジカルビュー社
- Data Source
  KAKENHI-PROJECT-26253058
[Book] PPARγをめぐる基礎研究の進展－エピゲノム解析をはじめとして. 期待されるチアゾリジン薬（改訂版）2013
- Author(s)
  脇裕典、山内敏正、門脇孝
- Total Pages
  12
- Publisher
  フジメディカル出版
- Data Source
  KAKENHI-PLANNED-23126101
[Book] 医学のあゆみ　白色脂肪細胞のエピジェネティックス2012
- Author(s)
  脇　裕典、山内敏正、門脇　孝
- Total Pages
  6
- Publisher
  医歯薬出版株式会社
- Data Source
  KAKENHI-PLANNED-23126101
[Book] アディポネクチンの臨床応用の現状・展望(Q&A)2007
- Author(s)
  山内敏正、門脇孝
- Publisher
  日本医事新報
- Data Source
  KAKENHI-PROJECT-18390270
[Book] 【メタボリックシンドロームup to date】検査・診断アディポネクチン2007
- Author(s)
  山内敏正、原一雄、門脇孝
- Publisher
  日本医師会雑誌
- Data Source
  KAKENHI-PROJECT-18390270
[Book] 特集糖尿病の新しい治療戦略インスリン抵抗性改善薬の現状と未来2007
- Author(s)
  山内敏正、門脇孝
- Publisher
  最新医学社
- Data Source
  KAKENHI-PROJECT-18390270
[Book] 【糖尿病の新しい治療戦略】糖尿病の治療戦略インスリン抵抗性改善薬の現状と未来2007
- Author(s)
  山内敏正、門脇孝
- Publisher
  最新医学
- Data Source
  KAKENHI-PROJECT-18390270
[Book] 【糖尿病による心血管合併症】インスリン抵抗性と動脈硬化症2007
- Author(s)
  山内敏正、門脇孝
- Publisher
  BIO Clinica
- Data Source
  KAKENHI-PROJECT-18390270
[Book] 脂質代議常-高脂血症・低脂血症-I概論高脂血症と動脈硬化動脈硬化発症にかかわるアディポサイトカインの役割2007
- Author(s)
  山内敏正、門脇孝
- Publisher
  日本臨牀
- Data Source
  KAKENHI-PROJECT-18390270
[Book] オスモチン2007
- Author(s)
  山内敏正、門脇孝
- Publisher
  臨床栄養
- Data Source
  KAKENHI-PROJECT-18390270
[Book] アディポサイトカイン調節を改善する食事療法2007
- Author(s)
  山内敏正、門脇孝
- Publisher
  Adiposcience
- Data Source
  KAKENHI-PROJECT-18390270
[Journal Article] Decreased AdipoR1 signaling and its implications for obesity-induced male infertility2024
- Author(s)
  Toshiko Kobori, Masato Iwabu, Miki Okada-Iwabu, Nozomi Ohuchi, Akiko Kikuchi, Naoko Yamauchi, Takashi Kadowaki, Toshimasa Yamauchi, and Masato Kasuga
- Journal Title
  
  Scientific Reports
  
  Volume: 14 Issue: 1 Pages: 5701-5701
- DOI
  10.1038/s41598-024-56290-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K21343, KAKENHI-PROJECT-22K11873, KAKENHI-PROJECT-23K24785
[Journal Article] A monoclonal antibody activating AdipoR for type 2 diabetes and nonalcoholic steatohepatitis2023
- Author(s)
  Naomi Asahara, Miki Okada-Iwabu, Masato Iwabu, Kouichi Wada, Kozo Oka, Toshimasa Yamauchi, and Takashi Kadowaki
- Journal Title
  
  Science Advances
  
  Volume: 9 Issue: 45 Pages: 4216-4216
- DOI
  10.1126/sciadv.adg4216
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K21343, KAKENHI-PROJECT-22K11873, KAKENHI-PROJECT-23K24785
[Journal Article] 脂肪細胞のエピジェネティック修飾と糖尿病2022
- Author(s)
  脇　裕典，山内敏正
- Journal Title
  
  月刊糖尿病
  
  Volume: 14(1) Pages: 22-27
- Data Source
  KAKENHI-PROJECT-20H04101
[Journal Article] Elucidating exercise-induced skeletal muscle signaling pathways and applying relevant findings to preemptive therapy for lifestyle-related diseases2022
- Author(s)
  Iwabu Masato、Okada-Iwabu Miki、Kadowaki Takashi、Yamauchi Toshimasa
- Journal Title
  
  Endocr J
  
  Volume: 69 Issue: 1 Pages: 1-8
- DOI
  10.1507/endocrj.EJ21-0294
- NAID
  130008145270
- ISSN
  0918-8959, 1348-4540
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K11639, KAKENHI-PROJECT-19H01052
[Journal Article] NFIA determines the cis-effect of genetic variation on Ucp1 expression in murine thermogenic adipocytes2022
- Author(s)
  Hiraike Y, Tsutsumi S, Wada T, Oguchi M, Saito K, Nakamura M, Ota S, Koebis M, Nakao H, Aiba A, Nagano G, Ohno H, Oki K, Yoneda M, Kadowaki T, Aburatani H, Waki H, Yamauchi T.
- Journal Title
  
  iScience
  
  Volume: 25 Issue: 8 Pages: 104729-104729
- DOI
  10.1016/j.isci.2022.104729
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K15346, KAKENHI-PROJECT-22K08672, KAKENHI-PROJECT-22K16415, KAKENHI-PROJECT-21K08557, KAKENHI-PROJECT-19K17976, KAKENHI-PLANNED-19H05744, KAKENHI-PROJECT-20H04101
[Journal Article] Lack of Brain Insulin Receptor Substrate-1 Causes Growth Retardation, With Decreased Expression of Growth Hormone?Releasing Hormone in the Hypothalamus2021
- Author(s)
  Hayashi Takanori、Kubota Tetsuya、Mariko Inoue、Takamoto Iseki、Aihara Masakazu、Sakurai Yoshitaka、Wada Nobuhiro、Miki Takashi、Yamauchi Toshimasa、Kubota Naoto、Kadowaki Takashi
- Journal Title
  
  Diabetes
  
  Volume: 70 Issue: 8 Pages: 1640-1653
- DOI
  10.2337/db20-0482
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07281, KAKENHI-PROJECT-19K08991, KAKENHI-PROJECT-19K17977, KAKENHI-PROJECT-19H01052, KAKENHI-PROJECT-21K19496
[Journal Article] Preparation and culture of bone marrow-derived macrophages from mice for functional analysis.2021
- Author(s)
  Gotaro Toda, Toshimasa Yamauchi, Takashi Kadowaki, and Kohjiro Ueki
- Journal Title
  
  STAR Protocols
  
  Volume: 2 Issue: 1 Pages: 100246-100246
- DOI
  10.1016/j.xpro.2020.100246
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K17954, KAKENHI-PROJECT-19H01052
[Journal Article] Body‐weight‐independent glucose‐lowering effect of the β3‐adrenergic receptor agonist mirabegron in humans2021
- Author(s)
  Waki Hironori、Yamauchi Toshimasa
- Journal Title
  
  Journal of Diabetes Investigation
  
  Volume: 12 Issue: 5 Pages: 689-690
- DOI
  10.1111/jdi.13509
- Open Access
- Data Source
  KAKENHI-PROJECT-20H04101
[Journal Article] 褐色脂肪細胞2021
- Author(s)
  脇裕典, 山内敏正
- Journal Title
  
  週刊医学のあゆみ　第５土曜特集　糖尿病治療・研究の最前線2021
  
  Volume: 276(5) Pages: 414-418
- Data Source
  KAKENHI-PROJECT-20H04101
[Journal Article] AdipoR agonist increases insulin sensitivity and exercise endurance in AdipoR-humanized mice2021
- Author(s)
  Iwabu Masato、Okada-Iwabu Miki、Tanabe Hiroaki、Ohuchi Nozomi、Miyata Keiko、Kobori Toshiko、Odawara Sara、Kadowaki Yuri、Yokoyama Shigeyuki、Yamauchi Toshimasa、Kadowaki Takashi
- Journal Title
  
  Communications Biology
  
  Volume: 4 Issue: 1 Pages: 45-45
- DOI
  10.1038/s42003-020-01579-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K11639, KAKENHI-PROJECT-18H04053, KAKENHI-PROJECT-19H01052, KAKENHI-PROJECT-18K10988
[Journal Article] Genome-Wide Association Studies Identify Two Novel Loci Conferring Susceptibility to Diabetic Retinopathy in Japanese Patients with Type 2 Diabetes.2021
- Author(s)
  Imamura M,・・・・・・・・・ Yamauchi T, Tobe K, Maegawa H, Kadowaki T, Maeda S.
- Journal Title
  
  Hum Mol Genet.
  
  Volume: なし Issue: 8 Pages: 716-726
- DOI
  10.1093/hmg/ddab044
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H04053, KAKENHI-PROJECT-20H03730
[Journal Article] Human adiponectin receptor AdipoR1 assumes closed and open structures2020
- Author(s)
  Tanabe Hiroaki、Fujii Yoshifumi、Okada-Iwabu Miki、Iwabu Masato、Kano Kuniyuki、Kawana Hiroki、Hato Masakatsu、Nakamura Yoshihiro、Terada Takaho、Kimura-Someya Tomomi、Shirouzu Mikako、Kawano Yoshiaki、Yamamoto Masaki、Aoki Junken、Yamauchi Toshimasa、Kadowaki Takashi、Yokoyama Shigeyuki
- Journal Title
  
  Communications Biology
  
  Volume: 3 Issue: 1 Pages: 446-446
- DOI
  10.1038/s42003-020-01160-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K11639, KAKENHI-PROJECT-19H01052, KAKENHI-PROJECT-18K10988
[Journal Article] NFIA differentially controls adipogenic and myogenic gene program through distinct pathways to ensure brown and beige adipocyte differentiation2020
- Author(s)
  Hiraike Yuta、Waki Hironori、Miyake Kana、Wada Takahito、Oguchi Misato、Saito Kaede、Tsutsumi Shuichi、Aburatani Hiroyuki、Yamauchi Toshimasa、Kadowaki Takashi
- Journal Title
  
  PLOS Genetics
  
  Volume: 16 Issue: 9 Pages: e1009044-e1009044
- DOI
  10.1371/journal.pgen.1009044
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-19H05739, KAKENHI-PLANNED-19H05744, KAKENHI-PROJECT-18H04053, KAKENHI-PROJECT-19H01031, KAKENHI-PROJECT-19H01052, KAKENHI-PROJECT-20H04101
[Journal Article] Blood Glucose Control Strategy for Type 2 Diabetes Patients With COVID-192020
- Author(s)
  Futatsugi Hiroyuki、Iwabu Masato、Okada-Iwabu Miki、Okamoto Koh、Amano Yosuke、Morizaki Yutaka、Kadowaki Takashi、Yamauchi Toshimasa
- Journal Title
  
  Frontiers in Cardiovascular Medicine
  
  Volume: 7 Pages: 593061-593061
- DOI
  10.3389/fcvm.2020.593061
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K11639, KAKENHI-PROJECT-19H01052
[Journal Article] Genome-wide association meta-analysis identifies GP2 gene risk variants for pancreatic cancer2020
- Author(s)
  Lin Y, Nakatochi M, Hosono Y, Ito H, Kamatani Y, Inoko A, Sakamoto H, Kinoshita F, Kobayashi Y, Ishii H, Yamaji T,et al.
- Journal Title
  
  Nature Communications
  
  Volume: 11 Issue: 1 Pages: 3175-3175
- DOI
  10.1038/s41467-020-16711-w
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K10655, KAKENHI-PROJECT-19K10659, KAKENHI-PROJECT-18KK0251, KAKENHI-PROJECT-18H02894, KAKENHI-PROJECT-18H04053, KAKENHI-PROJECT-18H02624, KAKENHI-PROJECT-19K22543, KAKENHI-PROJECT-19K22658, KAKENHI-PROJECT-19K17962, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-16H06279
[Journal Article] Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases2020
- Author(s)
  Ishigaki K, Akiyama M, Kanai M, Takahashi A, Kawakami E, Sugishita H, Sakaue S, Matoba N, Low SK, Okada Y, Yamaji T, et al
- Journal Title
  
  Nature Genetics
  
  Volume: 52 Issue: 7 Pages: 669-679
- DOI
  10.1038/s41588-020-0640-3
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K10655, KAKENHI-PROJECT-20K07709, KAKENHI-PROJECT-20K08288, KAKENHI-PROJECT-16H02468, KAKENHI-PROJECT-18H02894, KAKENHI-PLANNED-17H06419, KAKENHI-PROJECT-18H05285, KAKENHI-PROJECT-16H02676, KAKENHI-PROJECT-18H04053, KAKENHI-PROJECT-20H00543, KAKENHI-PROJECT-18H02688, KAKENHI-PROJECT-18H02931, KAKENHI-PROJECT-18H02932, KAKENHI-PROJECT-19H03559, KAKENHI-PROJECT-19H03881, KAKENHI-PROJECT-19K22525, KAKENHI-PROJECT-19K17962, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-20H03695, KAKENHI-PROJECT-20H03943, KAKENHI-PROJECT-18H02940
[Journal Article] Prolyl Hydroxylase Domain Inhibitor Protects against Metabolic Disorders and Associated Kidney Disease in Obese Type 2 Diabetic Mice2020
- Author(s)
  Mai Sugahara、Shinji Tanaka、Tetsuhiro Tanaka、Hisako Saito、Yu Ishimoto、Takeshi Wakashima、Masatoshi Ueda、Kenji Fukui、Akira Shimizu、Reiko Inagi、Toshimasa Yamauchi、Takashi Kadowaki、Masaomi Nangaku
- Journal Title
  
  Journal of the American Society of Nephrology
  
  Volume: 31 Issue: 3 Pages: 560-577
- DOI
  10.1681/asn.2019060582
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K17731, KAKENHI-PROJECT-18H04053, KAKENHI-PROJECT-19H01052, KAKENHI-PROJECT-17K09688, KAKENHI-PROJECT-26000012, KAKENHI-PROJECT-20K08626, KAKENHI-PROJECT-18H02727, KAKENHI-PROJECT-18H02824
[Journal Article] 【肥満-外科治療と基礎研究の最新情報】褐色脂肪細胞と白色脂肪細胞褐色・白色脂肪細胞における転写制御と肥満治療2020
- Author(s)
  脇裕典, 山内敏正
- Journal Title
  
  医学のあゆみ
  
  Volume: 274(10) Pages: 972-975
- Data Source
  KAKENHI-PROJECT-20H04101
[Journal Article] Insulin- and Lipopolysaccharide-Mediated Signaling in Adipose Tissue Macrophages Regulates Postprandial Glycemia through Akt-mTOR Activation2020
- Author(s)
  Toda G、Soeda K、Okazaki Y、Kobayashi N、Masuda Y、Arakawa N、Suwanai H、Masamoto Y、Izumida Y、Kamei N、Sasako T、Suzuki R、Kubota T、Kubota N、Kurokawa M、Tobe K、Noda T、Honda K、Accili D、Yamauchi T、Kadowaki T、Ueki K
- Journal Title
  
  Molecular Cell
  
  Volume: 79 Issue: 1 Pages: 1-2
- DOI
  10.1016/j.molcel.2020.04.033
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07898, KAKENHI-PROJECT-19K08991, KAKENHI-PROJECT-19K17954, KAKENHI-PROJECT-18H04052, KAKENHI-PROJECT-19H01052, KAKENHI-PROJECT-17K00846, KAKENHI-PROJECT-18K15075
[Journal Article] Robust and highly efficient hiPSC generation from patient non-mobilized peripheral blood-derived CD34+ cells using the auto-erasable Sendai virus vector.2019
- Author(s)
  Okumura T, Horie Y, et al.
- Journal Title
  
  Stem Cell Res Ther.
  
  Volume: 10 Issue: 1 Pages: 185-185
- DOI
  10.1186/s13287-019-1273-2
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08246, KAKENHI-PROJECT-18K16141, KAKENHI-PROJECT-18H04053, KAKENHI-PROJECT-19H01052, KAKENHI-PROJECT-17K09971, KAKENHI-PROJECT-17K10099, KAKENHI-PROJECT-17K19600, KAKENHI-PROJECT-26000012
[Journal Article] Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population.2019
- Author(s)
  Suzuki K, Akiyama M, Ishigaki K, Kanai M, Hosoe J, Shojima N, Hozawa A, Kadota A, Kuriki K, Naito M, Tanno K, Ishigaki Y, et al.
- Journal Title
  
  Nat Genet.
  
  Volume: 51 Issue: 3 Pages: 379-386
- DOI
  10.1038/s41588-018-0332-4
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08523, KAKENHI-PROJECT-18H04053, KAKENHI-PROJECT-16H05378, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-17H03596, KAKENHI-PROJECT-17H04251, KAKENHI-PROJECT-26000012
[Journal Article] Adiponectin/AdipoR Research and Its Implications for Lifestyle-Related Diseases2019
- Author(s)
  Iwabu Masato、Okada-Iwabu Miki、Yamauchi Toshimasa、Kadowaki Takashi
- Journal Title
  
  Frontiers in Cardiovascular Medicine
  
  Volume: 6 Pages: 116-116
- DOI
  10.3389/fcvm.2019.00116
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K10988, KAKENHI-PROJECT-19K11639, KAKENHI-PROJECT-18H04053, KAKENHI-PROJECT-19H01052, KAKENHI-PROJECT-26000012
[Journal Article] Critical Role of SREBP-1c Large-VLDL Pathway in Environment-Induced Hypertriglyceridemia of Apo AV Deficiency2019
- Author(s)
  Takanashi M, Kimura T, Li C, Tanaka M, Matsuhashi A, Yoshida H, Noda A, Xu P, Takase S, Okazaki S, Iizuka Y, Kumagai H, Ikeda Y, Gotoda T, Takahashi M, Yagyu H, Ishibashi S, Yamauchi T, Kadowaki T, Liang G, Okazaki H.
- Journal Title
  
  Arteriosclerosis, Thrombosis, and Vascular Biology
  
  Volume: 39 Issue: 3 Pages: 373-386
- DOI
  10.1161/atvbaha.118.311931
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08585, KAKENHI-PROJECT-17K09858, KAKENHI-PROJECT-18K08504, KAKENHI-PROJECT-18H04053, KAKENHI-PROJECT-17K09867, KAKENHI-PROJECT-26000012
[Journal Article] Differential effects of diet- and genetically-induced brain insulin resistance on amyloid pathology in a mouse model of Alzheimer’s disease2019
- Author(s)
  Tomoko Wakabayashi, Kazuki Yamaguchi, Kentaro Matsui, Toshiharu Sano, Tetsuya Kubota, Tadafumi Hashimoto, Ayako Mano, Kaoru Yamada, Yuko Matsuo, Naoto Kubota, Takashi Kadowaki, Takeshi Iwatsubo
- Journal Title
  
  Molecular Neurodegeneration
  
  Volume: 14 Issue: 1 Pages: 15-15
- DOI
  10.1186/s13024-019-0315-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07364, KAKENHI-PROJECT-19K08991, KAKENHI-PROJECT-19H01052, KAKENHI-PROJECT-26000012, KAKENHI-PROJECT-17H04193, KAKENHI-PROJECT-18H02860
[Journal Article] Drug development research for novel adiponectin receptor-targeted antidiabetic drugs contributing to healthy longevity2019
- Author(s)
  Okada-Iwabu Miki、Iwabu Masato、Yamauchi Toshimasa、Kadowaki Takashi
- Journal Title
  
  DIABETOLOGY INTERNATIONAL
  
  Volume: 10 Issue: 4 Pages: 237-244
- DOI
  10.1007/s13340-019-00409-6
- NAID
  40022039924
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K10988, KAKENHI-PROJECT-19K11639, KAKENHI-PROJECT-18H04053, KAKENHI-PROJECT-19H01052, KAKENHI-PROJECT-26000012
[Journal Article] NAD + supplementation rejuvenates aged gut adult stem cells2019
- Author(s)
  Igarashi M*, Miura M, Williams E, Jaksch F, Kadowaki T, Yamauchi T* , Guarente L
- Journal Title
  
  Aging Cell
  
  Volume: - Issue: 3 Pages: 1-10
- DOI
  10.1111/acel.12935
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H04053, KAKENHI-PROJECT-17H06631, KAKENHI-PROJECT-19K09017, KAKENHI-PROJECT-19H01052, KAKENHI-PROJECT-26000012
[Journal Article] Structure and function analysis of adiponectin receptors toward development of novel antidiabetic agents promoting healthy longevity2018
- Author(s)
  Okada-Iwabu Miki、Iwabu Masato、Yamauchi Toshimasa、Kadowaki Takashi
- Journal Title
  
  Endocr J
  
  Volume: 65 Issue: 10 Pages: 971-977
- DOI
  10.1507/endocrj.EJ18-0310
- NAID
  130007501453
- ISSN
  0918-8959, 1348-4540
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K10988, KAKENHI-PROJECT-26000012
[Journal Article] Downregulation of macrophage Irs2 by hyperinsulinemia impairs IL-4-indeuced M2a-subtype macrophage activation in obesity2018
- Author(s)
  Kubota Tetsuya、Inoue Mariko、Kubota Naoto、Takamoto Iseki、Mineyama Tomoka、Iwayama Kaito、Tokuyama Kumpei、Moroi Masao、Ueki Kohjiro、Yamauchi Toshimasa、Kadowaki Takashi
- Journal Title
  
  Nature Communications
  
  Volume: 9 Issue: 1 Pages: 4863-4863
- DOI
  10.1038/s41467-018-07358-9
- NAID
  120007133395
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19556, KAKENHI-PROJECT-18H04053, KAKENHI-PROJECT-26000012
[Journal Article] A variant within the FTO confers susceptibility to diabetic nephropathy in Japanese patients with type 2 diabetes2018
- Author(s)
  Taira M, Imamura M,・, Yamauchi T, ・Kadowaki T, Maeda S:
- Journal Title
  
  PLOS ONE
  
  Volume: 13 Issue: 12 Pages: e0208654-e0208654
- DOI
  10.1371/journal.pone.0208654
- NAID
  120006822492
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H04053
[Journal Article] NFIA co-localizes with PPARγ and transcriptionally controls the brown fat gene program.2017
- Author(s)
  Hiraike Y, Waki H, Yu J, Nakamura M, Miyake K, Nagano G, Nakaki R, Suzuki K, Kobayashi H, Yamamoto S, Sun W, Aoyama T, Hirota Y, Ohno H, Oki K, Yoneda M, White AP, Tseng YH, Cypess AM, Larsen TJ, Jespersen NZ, Scheele C, Tsutsumi S, Aburatani H, Yamauchi T, Kadowaki T
- Journal Title
  
  Nature cell biology
  
  Volume: 19(9) Issue: 9 Pages: 1081-1092
- DOI
  10.1038/ncb3590
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09818, KAKENHI-PROJECT-17K09883, KAKENHI-PROJECT-16H06226, KAKENHI-PROJECT-26000012
[Journal Article] Glycemic control, mortality, and hypoglycemia in critically ill patients: a systematic review and network meta-analysis of randomized controlled trials.2017
- Author(s)
  Yamada T, Shojima N, Noma H, Yamauchi T, Kadowaki T.
- Journal Title
  
  Intensive Care Medicine
  
  Volume: 43 Issue: 1 Pages: 1-15
- DOI
  10.1007/s00134-016-4523-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09409, KAKENHI-PROJECT-16K20965, KAKENHI-PROJECT-26000012
[Journal Article] CDK5 Regulatory Subunit-Associated Protein l-like I Negatively Regulates Adipocyte Differentiation through Activation of Wnt Signaling Pathway.2017
- Author(s)
  Take K, Waki H, Sun W, Wada T, Yu J, Nakamura M, Aoyama T, Yamauchi T, Kadowaki T
- Journal Title
  
  Sci Rep.
  
  Volume: 7 Issue: 1 Pages: 7326-7326
- DOI
  10.1038/s41598-017-06469-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26000012
[Journal Article] J-curve relation between daytime nap duration and type 2 diabetes or metabolic syndrome: A dose-response meta-analysis.2016
- Author(s)
  Yamada T, Shojima N, Yamauchi T, Kadowaki T
- Journal Title
  
  Scientific Report
  
  Volume: 6 Issue: 1 Pages: 38075-38075
- DOI
  10.1038/srep38075
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09409, KAKENHI-PROJECT-16K20965, KAKENHI-PROJECT-26000012
[Journal Article] Lactic acidosis due to attempted suicide with metformin overdose: A case report.2016
- Author(s)
  Yamada T, Shojima N, Yamauchi T, Kadowaki T.
- Journal Title
  
  Diabetes Metabolism
  
  Volume: 42 Issue: 4 Pages: 290-291
- DOI
  10.1016/j.diabet.2016.03.005
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09409, KAKENHI-PROJECT-26000012
[Journal Article] Genome-wide association studies in the Japanese population identify seven novel loci for type 2 diabetes.2016
- Author(s)
  Imamura M, ・・Yamauchi T,・・ Shojima N, ・・Kadowaki T
- Journal Title
  
  Nat Commun.
  
  Volume: 7 Issue: 1 Pages: 10531-10531
- DOI
  10.1038/ncomms10531
- NAID
  120006889946
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09409, KAKENHI-PUBLICLY-15H01507, KAKENHI-PLANNED-15H05911, KAKENHI-PROJECT-26253058, KAKENHI-PROJECT-15H05670, KAKENHI-PROJECT-26461327, KAKENHI-PROJECT-26000012
[Journal Article] Adiponectin/adiponectin receptor in disease and aging.2015
- Author(s)
  Iwabu M, Okada-Iwabu M, Yamauchi T, Kadowaki T
- Journal Title
  
  npj Aging and Mechanisms of Disease
  
  Volume: 1 Issue: 1 Pages: 15013-15013
- DOI
  10.1038/npjamd.2015.13
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26293216, KAKENHI-PROJECT-26713032, KAKENHI-PROJECT-26000012
[Journal Article] Daytime Napping and the Risk of Cardiovascular Disease and All-Cause Mortality: A Prospective Study and Dose-Response Meta-Analysis.2015
- Author(s)
  Yamada T, Hara K, Shojima N, Yamauchi T, Kadowaki T
- Journal Title
  
  Sleep
  
  Volume: 38 Issue: 12 Pages: 1945-1953
- DOI
  10.5665/sleep.5246
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09409, KAKENHI-PUBLICLY-15H01507, KAKENHI-PROJECT-26253058, KAKENHI-PROJECT-26000012
[Journal Article] Perspective of Small-Molecule AdipoR Agonist for Type 2 Diabetes and Short Life in Obesity2015
- Author(s)
  Okada-Iwabu M, Iwabu M, Ueki K, Yamauchi T and Kadowaki T.
- Journal Title
  
  Diabetes Metab J
  
  Volume: 39 Issue: 5 Pages: 363-372
- DOI
  10.4093/dmj.2015.39.5.363
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H05789, KAKENHI-PROJECT-26293216, KAKENHI-PROJECT-26713032, KAKENHI-PROJECT-26000012
[Journal Article] Perspective of Small-Molecule AdipoR Agonist for Type 2 Diabetes and Short Life in Obesity.2015
- Author(s)
  Okada-Iwabu M, Iwabu M, Ueki K, Yamauchi T, Kadowaki T
- Journal Title
  
  Diabetes Metab J
  
  Volume: 39 Pages: 363-372
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01507
[Journal Article] Perspective of Small-Molecule AdipoR Agonist for Type 2 Diabetes and Short Life in Obesity.2015
- Author(s)
  Okada-Iwabu M, Iwabu M, Ueki K, Yamauchi T, Kadowaki T
- Journal Title
  
  Diabetes Metab J
  
  Volume: 39 Pages: 363-372
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26253058
[Journal Article] Crystal structures of the human adiponectin receptors.2015
- Author(s)
  Tanabe H, Fujii Y, Okada-Iwabu M, Iwabu M, Nakamura Y, Hosaka T, Motoyama K, Ikeda M, Wakiyama M, Terada T, Ohsawa N, Hato M, Ogasawara S, Hino T, Murata T, Iwata S, Hirata K, Kawano Y, Yamamoto M, Kimura-Someya T, Shirouzu M, Yamauchi T, Kadowaki T, Yokoyama S
- Journal Title
  
  Nature
  
  Volume: 520 Issue: 7547 Pages: 312-316
- DOI
  10.1038/nature14301
- NAID
  40020952688
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01507, KAKENHI-PROJECT-26253058, KAKENHI-PROJECT-26293216, KAKENHI-PROJECT-25711004, KAKENHI-PROJECT-26713032, KAKENHI-PROJECT-26000012
[Journal Article] Expression, purification, crystallization, and preliminary X-ray crystallographic studies of the human adiponectin receptors, AdipoRl and AdipoR22015
- Author(s)
  Tanabe H,..., Iwata S, Okada-Iwabu M, Iwabu M,..., Yamauchi T, Kadowaki T, and Yokoyama S
- Journal Title
  
  J. Struct. Funct. Genomics
  
  Volume: 16 Issue: 1 Pages: 11-23
- DOI
  10.1007/s10969-014-9192-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26000012, KAKENHI-PROJECT-26253058, KAKENHI-PROJECT-26293216, KAKENHI-PROJECT-26713032
[Journal Article] Adiponectin regulates psoriasiform skin inflammation by suppressing IL-17 production from γ δ-T cells.2015
- Author(s)
  Shibata S, Tada Y, Hau CS, Mitsui A, Kamata M, Asano Y, Sugaya M, Kadono T, Masamoto Y, Kurokawa M, Yamauchi T, Kubota N, Kadowaki T, Sato S
- Journal Title
  
  Nat. Commun.
  
  Volume: 6 Pages: 7687-7687
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26000012
[Journal Article] Successfully achieving target weight loss influences subsequent maintenance of lower weight and dropout from treatment2015
- Author(s)
  Yamada T, Hara K, Svensson A, Shojima N, Hosoe J, Iwasaki M, Yamauchi T, Kadowaki T
- Journal Title
  
  Obesity(Silver Spring)
  
  Volume: 23 Issue: 1 Pages: 183-191
- DOI
  10.1002/oby.20874
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26000012, KAKENHI-PROJECT-26253058
[Journal Article] A Novel Peroxisome Proliferator-activated Receptor (PPAR)α Agonist and PPARγ Antagonist, Z-551, Ameliorates High-fat Diet-induced Obesity and Metabolic Disorders in Mice.2015
- Author(s)
  Shiomi Y, Yamauchi T, Iwabu M, Okada-Iwabu M, Nakayama R, Orikawa Y, Yoshioka Y, Tanaka K, Ueki K, Kadowaki T
- Journal Title
  
  J Biol Chem
  
  Volume: 290 Issue: 23 Pages: 14567-14581
- DOI
  10.1074/jbc.m114.622191
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01507, KAKENHI-PROJECT-15H05789, KAKENHI-PROJECT-23228001, KAKENHI-PROJECT-24249077, KAKENHI-PROJECT-26253058, KAKENHI-PROJECT-26282223, KAKENHI-PROJECT-26293216, KAKENHI-PROJECT-26713032, KAKENHI-PROJECT-26000012
[Journal Article] 糖尿病と遺伝子 4．糖尿病とエピゲノム2014
- Author(s)
  脇裕典, 山内敏正, 門脇孝
- Journal Title
  
  糖尿病
  
  Volume: 57(2) Pages: 91-93
- Data Source
  KAKENHI-PLANNED-23126101
[Journal Article] エピゲノムと肥満症2014
- Author(s)
  脇裕典, 山内敏正, 門脇孝
- Journal Title
  
  医学のあゆみ (第5土曜特集肥満の医学 : 臨床と研究の最先端)
  
  Volume: 250(9) Pages: 797-801
- Data Source
  KAKENHI-PLANNED-23126101
[Journal Article] 核内受容体PPARと脂肪酸2013
- Author(s)
  脇裕典, 山内敏正, 門脇孝
- Journal Title
  
  月刊内分泌・糖尿病・代謝内科
  
  Volume: 36(6) Pages: 558-564
- NAID
  40019739361
- Data Source
  KAKENHI-PLANNED-23126101
[Journal Article] Adiponectin receptor as a key player in healthy longevity and obesity-related diseases2013
- Author(s)
  Yamauchi T, Kadowaki T.
- Journal Title
  
  Cell Metab
  
  Volume: 17 Issue: 2 Pages: 185-196
- DOI
  10.1016/j.cmet.2013.01.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20229008
[Journal Article] Genome-wide association study in a Chinese population identifies a susceptibility locus for type 2 diabetes at 7q32 near PAX42013
- Author(s)
  Ma R. C. W., Hu C., Tam C. H.,..., Hara K.,..., Yamauchi T.,..., Kadowaki T., Tai E. S., Zeggini E., McCarthy M. I., Hon K. L., Baum L., Tomlinson B., So W. Y., Bao Y., Chan J. C. N., Jia W
- Journal Title
  
  Diabetologia
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20229008
[Journal Article] Genome-wide Association Study Identifies a Novel Locus Contributing to Type 2 Diabetes Susceptibility in Sikhs of Punjabi Origin From India2013
- Author(s)
  Saxena R, Yamauchi T, Hara K Saxena R, Yamauchi T, Hara K DIAGRAM MuTHER; TGEN, Kadowaki T
- Journal Title
  
  Diabetes
  
  Volume: 62 Issue: 5 Pages: 1746-1755
- DOI
  10.2337/db12-1077
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20229008, KAKENHI-PROJECT-23591327, KAKENHI-PROJECT-24510276, KAKENHI-PROJECT-25253068
[Journal Article] Diabetes Genetics Replication and Meta-analysis (DIAGRAM) Consortium, Nakamura Y, Kadowaki T: A single-nucleotide polymorphism in ANK1 is associated with susceptibility to type 2 diabetes in Japanese populations2012
- Author(s)
  Imamura M,1,Yamauchi T, Hara K, Okada-Iwabu M, Iwabu M
- Journal Title
  
  Human Molecular Genatics
  
  Volume: 21 Pages: 3042-3049
- Data Source
  KAKENHI-PROJECT-20229008
[Journal Article] Monocyte chemoattractant protein-1 (MCP-1) deficiency enhances alternatively activated M2 macrophages and ameliorates insulin resistance and fatty liver in lipoatrophic diabetic A-ZIP transgenic mice2012
- Author(s)
  Nio Y, Yamauchi T, Iwabu M, Okada-Iwabu M, Ueki K, Kadowaki T
- Journal Title
  
  Diabetologia
  
  Volume: 55 Issue: 12 Pages: 3350-3358
- DOI
  10.1007/s00125-012-2710-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20229008, KAKENHI-PROJECT-23689048, KAKENHI-PROJECT-24790908
[Journal Article] SnapShot: Physiology of Insulin Signaling2012
- Author(s)
  Kadowaki T, Kubota N, Ueki K, Yamauchi T
- Journal Title
  
  Ce11
  
  Volume: 148 Pages: 834-834
- Data Source
  KAKENHI-PROJECT-20229008
[Journal Article] A single-nucleotide polymorphism in ANK1 is associated with susceptibility to type 2 diabetes in Japanese populations.2012
- Author(s)
  Imamura M, Maeda S, Yamauchi T, Hara K, Yasuda K,..., Okada-Iwabu M, Iwabu M, Shojima N,..., Nakamura Y, Kadowaki T
- Journal Title
  
  Human Molecular Genetics
  
  Volume: 21 Issue: 13 Pages: 3042-3049
- DOI
  10.1093/hmg/dds113
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20229008, KAKENHI-PROJECT-22591021, KAKENHI-PROJECT-23591361, KAKENHI-PROJECT-24510276, KAKENHI-PROJECT-23689048, KAKENHI-PROJECT-24790908
[Journal Article] SnapShot : Physiology of Insulin Signaling2012
- Author(s)
  Kadowaki T, Kubota N, Ueki K, Yamauchi T
- Journal Title
  
  Cell
  
  Volume: 148 Issue: 4 Pages: 834-834
- DOI
  10.1016/j.cell.2012.02.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20229008
[Journal Article] Depletion of homeodomain-interacting protein kinase 3 impairs insulin secretion and glucose tolerance in mice2012
- Author(s)
  Shojima N, Hara K, Kubota N, Yamauchi T, Ueki K, Kadowaki T
- Journal Title
  
  Diabetologia
  
  Volume: 55 Issue: 12 Pages: 3318-3330
- DOI
  10.1007/s00125-012-2711-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20229008
[Journal Article] Snap Shot: Insulin Signaling Pathways2012
- Author(s)
  Kadowaki T, Ueki K, Yamauchi T, Kubota N.
- Journal Title
  
  Cep
  
  Volume: 148 Pages: 624-624
- Data Source
  KAKENHI-PROJECT-20229008
[Journal Article] SnapShot : Insulin Signaling Pathways2012
- Author(s)
  Kadowaki T, Ueki K, Yamauchi T, Kubota N
- Journal Title
  
  Cell
  
  Volume: 148 Issue: 3 Pages: 624-624
- DOI
  10.1016/j.cell.2012.01.034
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20229008
[Journal Article] Adiponectin enhances insulin sensitivity by increasing hepatic IRS-2 expression via a macrophage妖erived IL-6 dependent pathway2011
- Author(s)
  Awazawa M, Ueki K, Yamauchi T, Kubota, Kadowaki T
- Journal Title
  
  Cell Metabolism
  
  Volume: 13 Issue: 4 Pages: 401-412
- DOI
  10.1016/j.cmet.2011.02.010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20229008, KAKENHI-PROJECT-21390278, KAKENHI-PROJECT-23791019
[Journal Article] Possibility of increasing cholesterol efflux by adiponectin and its receptors through the ATP binding cassette transporter A1 in HEK293T cells2011
- Author(s)
  Kitajima, K,Miura S, Yamauchi T, Uehara Y, Kiya Y, Rye KA, Kadowaki T, Saku K
- Journal Title
  
  Biochem.Biophys.Res.Commun.
  
  Volume: 411 Issue: 2 Pages: 305-311
- DOI
  10.1016/j.bbrc.2011.06.131
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20229008
[Journal Article] Impaired insulin signaling in the endothelial cells reduces insulin-induced glucose uptake by the skeletal muscle.2011
- Author(s)
  Kubota T, Kubota N, Kumagai H, Yamaguchi S, Kozono H, Takahashi T, Inoue M, Itoh S, Takamoto I, Sasako T, Kumagai K, Kawai T, Hashimoto S, Kobayashi T, Sato M, Tokuyama K, Nishimura S, Tsunoda M, Ide T, Murakami K, Yamazaki T, Ezaki O, Kawamura K, Masuda H, Moroi M, Sugi K, Oike Y, Shimokawa H, Yanagihara N, Tsutsui M, Terauchi Y, Tobe K, Nagai R, Kamata K, Inoue K, Kodama T, Ueki K, Kadowaki T
- Journal Title
  
  Cell Metabolism 13
  
  Pages: 294-307
- Data Source
  KAKENHI-PROJECT-20229008
[Journal Article] Adiponectin receptor signaling : a new layer to the current model.2011
- Author(s)
  Kadowaki T, Yamauchi T.
- Journal Title
  
  Cell Meabolism
  
  Volume: 13 Pages: 123-124
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22126007
[Journal Article] Thiazolidinediones Enhance Sodium-Coupled Bicarbonate Absorption from Renal Proximal Tubules via PPARγ-Dependent Nongenomic Signaling2011
- Author(s)
  Endo Y, Suzuki M, Yamada H, Horita s, Kunimi M, Yamazaki O, Shirai A, Nakamura M, Iso-O N, Li Y, Hara M, Tsukamoto K, Moriyama N, Kudo A, Kawakami H, Yamauchi T, Kubota N, Kadowaki T, Kume H, Enomoto Y, Homma Y, Seki G, Fujita T
- Journal Title
  
  Cell Metabolism
  
  Volume: 13 Pages: 550-561
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20229008
[Journal Article] Impaired insulin signaling in endothelial cells reduces insulin-induced glucose uptake by skeletal muscle.2011
- Author(s)
  Kubota T, Kubota N, Kumagai H, Yamaguchi S, Kozono H, Takahashi T, Inoue M, Itch S, Takamoto I, Sasako T, Kumagai K, Kawai T, Hashimoto S, Kobayashi T, Sato M, Tokuyama K, Nishimura S, Tsunoda M, Ide T, Murakami K, Yamazaki T, Ezaki 0, Kawamura K, Masuda H, Moroi M, Sugi K, Oike Y, Shimokawa H, Yanagihara N, TsutsuiM, Terauchi Y, Tobe K, Nagai R, Kamata K, Inoue K, Kodama T, Ueki K, Kadowaki T.
- Journal Title
  
  Cell Metab.
  
  Volume: 13 Pages: 294-307
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20229008
[Journal Article] Adiponectin receptor signaling : a new layer to the current model.2011
- Author(s)
  Kadowaki T, Yamauchi T.
- Journal Title
  
  Cell Metab.
  
  Volume: 13 Pages: 123-124
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20229008
[Journal Article] Adiponectin receptor signaling : a new layer to the current model.2011
- Author(s)
  Kadowaki T, Yamauchi T
- Journal Title
  
  Cell Metabolism 13
  
  Pages: 123-124
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390254
[Journal Article] Adiponectin enhances insulin sensitivity by increasing hepatic IRS-2 expression via macrophage-derived IL-6 dependent pathway.2011
- Author(s)
  Awazawa M, Ueki K, Inabe K, Yamauchi T, Kubota N, Kaneko K, Kobayashi M, Iwane A, Sasako T, Ohsugi M, Takamoto I, Yamashita S, Asahara H, Akira S, Kasuga M, Kadowaki T
- Journal Title
  
  Cell Metabolism 13
  
  Pages: 401-412
- Data Source
  KAKENHI-PROJECT-20229008
[Journal Article] Adiponectin receptor signaling : a new layer to the current model.2011
- Author(s)
  Kadowaki T, Yamauchi T.
- Journal Title
  
  Cell Meabolism
  
  Volume: 13 Pages: 123-124
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390254
[Journal Article] The diabetogenic VPS13C/C2CD4A/C2CD4B rs7172432 variant impairs glucose-stimulated insulin response in 5,722 non-diabetic Danish individuals2011
- Author(s)
  Grarup N, Yamauchi T, Hara K, Kadowaki T
- Journal Title
  
  Diabetologia
  
  Volume: 54 Issue: 4 Pages: 789-794
- DOI
  10.1007/s00125-010-2031-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20229008
[Journal Article] Adiponectin receptor signaling: a new layer to the current model2011
- Author(s)
  Kadowaki T, Yamauchi T
- Journal Title
  
  Cell Metabolism
  
  Volume: 13 Issue: 2 Pages: 123-124
- DOI
  10.1016/j.cmet.2011.01.012
- Data Source
  KAKENHI-PROJECT-20229008
[Journal Article] Crystal structure of the Ca2+/Calmodulin-dependent protein kinase in complex with the inhibitor STO-6092011
- Author(s)
  Kukimoto-Nino M, Yamauchi T, Okada Iwabu M, Iwabu M, Kadowaki T
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 286 Issue: 25 Pages: 22570-22579
- DOI
  10.1074/jbc.m111.251710
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20229008, KAKENHI-PROJECT-21390067, KAKENHI-PROJECT-23689048
[Journal Article] The diabetogenic VPS13C/C2CD4A/C2CD4B rs7172432 variant impairs glucose-stimulated insulin response in 5,722 non-diabetic Danish individuals.2011
- Author(s)
  Grarup N, Overvad M, Sparso T, Witte DR, Oisinger C, Jorgensen T, Yamauchi T, Hara K, Maeda S, Kadowaki T, Hansen T, Pedersen O.
- Journal Title
  
  Diabetologia
  
  Volume: 54 Pages: 789-794
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22126007
[Journal Article] Global mapping of cell type-specific open chromatin by FAIRE-seq reveals the regulatory role of the NFI family in adipocyte differentiation2011
- Author(s)
  Waki H, Nakamura M, Yamauchi T, Wakabayashi K, Yu J, Hirose-Yotsuya L, Take K, Sun W, Iwabu M, Okada-Iwabu M, Fujita T, Aoyama T, Tsutsumi S, Ueki K, Kodama T, Sakai J, Aburatani H, Kadowaki
- Journal Title
  
  PLos Genetics
  
  Volume: 7 Issue: 10 Pages: e1002311-e1002311
- DOI
  10.1371/journal.pgen.1002311
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10J03451, KAKENHI-PROJECT-20221009, KAKENHI-PROJECT-20229008, KAKENHI-PROJECT-22229009, KAKENHI-PLANNED-23126101, KAKENHI-PROJECT-23791020, KAKENHI-PROJECT-23689048
[Journal Article] The diabetogenic VPS13C/C2CD4A/C2CD4B rs7172432 variant impairs glucose-stimulated insulin response in 5,722 non-diabetic Danish individuals.2011
- Author(s)
  Grarup N, Overvad M, Sparso T, Witte DR, Oisinger C, Jorgensen T, Yamauchi T, Hara K, Maeda S, Kadowaki T, Hansen T, Pedersen O.
- Journal Title
  
  Diabetologia
  
  Volume: 54 Pages: 789-794
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390254
[Journal Article] Adiponectin and AdipoR1 regulate PGC-lalpha and mitochondria by Ca(2+)and AMPK/SIRT1.2010
- Author(s)
  Iwabu M, Yamauchi T, Okada-Iwabu M, Sato K, Nakagawa T, Funata M, Yamaguchi M, Namiki S, Nakayama R, Tabata M, Ogata H, Kubota N, Takamoto I, Hayashi YK, Yamauchi N, Waki H, Fukayama M, Nishino I, Tokuyama K, Ueki K, Oike Y, Ishii S, Hirose K, Shimizu T, Touhara K, Kadowaki T.
- Journal Title
  
  Nature (published online Mar.31,2010)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390254
[Journal Article] A genome-wide association study in the Japanese population identifies susceptibility loci for type 2 diabetes at UBEZE2 and C2CD4A-C2CD4B.2010
- Author(s)
  Yamauchi T, Hara K, Maeda S, Yasuda K, Takahashi A, Horikoshi M, Nakamura M, Fujito H, Grarup N, Cauchi S, Ng DPK, Ma RCW, Tsunoda T, Kubo M, Watada H, Maegawa H, Okada-lwabu M, Iwabu M, Shojima N, Shin HD, Andersen G, Witte DR, Jorgensen T, Lauritzen T, Sandbak A, Hansen T, Ohshige T, Omori S, Saito I, Kaku K, Hirose H, So WY, Beury D, Chan JCN, Park KS, Tai ES, Ito C, Tanaka Y, Kashiwag A, Kawamori R, Kasuga M, Frogue P, Pedersen O, Kamatani N, Nakamura Y, Kadowaki T
- Journal Title
  
  Nature Genetics
  
  Volume: 42 Pages: 864-868
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20229008
[Journal Article] Adiponectin receptors are downregulated in human gastric cancer.2010
- Author(s)
  Otani K, Kitayama J, Kamei T, Soma D, Miyato H, Yamauchi T, Kadowaki T, Nagawa H
- Journal Title
  
  Journal of Gastroenterology
  
  Volume: 45 Pages: 918-927
- NAID
  10027698901
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22126007
[Journal Article] Adiponectin suppresses tumorigenesis in Apc(Min)(/+)mice.2010
- Author(s)
  Otani K, Kitayama J, Yasuda K, Nio Y, Iwabu M, Okudaira S, Aoki J, Yamauchi T, Kadowaki T, Nagawa H.
- Journal Title
  
  Cancer Lett. 288
  
  Pages: 177-182
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390254
[Journal Article] Adiponectin and AdipoR1 regulate PGC-lalpha and mitochondria by Ca(2+) and AMPK/SIRT12010
- Author(s)
  Iwabu M, Yamauchi T, Okada-Iwabu M, Sato K, Nakagawa T, Funata M, Yamaguchi M, Namiki S, Nakayama R, Tabata M, Ogata H, Kubota N, Takamoto I, Hayashi YK, Yamauchi N, Waki H, Fukayama M, Nis hino I, Tokuyama K, Ueki K, Oike Y, Ishii S, Hirose K, Shimizu T, Touhara K, Kadowaki T.
- Journal Title
  
  Nature
  
  Volume: 464 Pages: 1313-1319
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390254
[Journal Article] Adiponectin and AdipoR1 regulate PGC-1α and mitochondria by Ca^<2+> and AMPK/SIRT1.2010
- Author(s)
  Iwabu M, Yamauchi T, Okada-Iwabu M, Sato K, Nakagawa T, Funata M, Yamaguchi M, Namiki S, Nakayama R, Tabata M, Ogata H, Kubota N, Takamoto I, Hayashi K.Y, Yamauchi N, Waki H, Fukayama M, Nishino I, Tokuyama K, Ueki K, Oike Y, Ishii S, Hirose K, Shimizu T, Touhara K, Kadowaki T
- Journal Title
  
  Nature 434
  
  Pages: 1313-1319
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390254
[Journal Article] Adiponectin and AdipoRl regulate PGCI and mitochondria by Ca^<2+> and AMPK/SIRTI.2010
- Author(s)
  Iwabu M, Yamauchi T, Okada-lwabu M, Sato K, Nakagawa T, Funata M, Pamaguchi M, Namiki S, Nakayama R, Tabata M, Ogata H, .Kubota N, Takamoto I, Hayashi YK, Yamauchi N, Waki H, Fukayama M, Nishino I, Tokuyama K, Ueki K, Oike Y, Ishii S, Hirose K, Shimizu T, Touhara K, Kadowaki T
- Journal Title
  
  Nature
  
  Volume: 464 Pages: 1313-1319
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20229008
[Journal Article] A genome-wide association study in the Japanese population identifies susceptibility loci for type 2 diabetes at UBE2E2 and C2CD4A-C2CD4B.2010
- Author(s)
  Yamauchi T, Hara K, Maeda S, Yasuda K, Takahashi A, Horikoshi M, Nakamura M, Fujita H, Grarup N, Cauchi S, Ng DP, Ma RC, Tsunoda T, Kubo M, Watada H, Maegawa H, Okada-Iwabu M, Iwabu M, Shojima N, Shin HD, Andersen G, Witte DR, Jorgensen T, Lauritzen T, Sandbaek A, Hansen T, Ohshige T, Omori S, Saito I, Kaku K, Hirose H, So WY, Beury D, Chan JC, Park KS, Tai ES, Ito C, Tanaka Y, Kashiwagi A, Kawamori R, Kasuga M, Froguel P, Pedersen O, Kamatani N, Nakamura Y, Kadowaki T
- Journal Title
  
  Nature Genetics
  
  Volume: 42 Pages: 864-868
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22126007
[Journal Article] genome-wide association study in the Japanese population identifies susceptibility loci for type 2 diabetes at UBE2E2 and C2CD4A-C2CD4B2010
- Author(s)
  Yamauchi T, Ham K, Iwabu M, Okada-Iwabu M, Kadowaki T
- Journal Title
  
  Nature Genetics
  
  Volume: 42 Issue: 10 Pages: 864-868
- DOI
  10.1038/ng.660
- Data Source
  KAKENHI-PROJECT-20229008
[Journal Article] Adiponectin receptors are downregulated in human gastric cancer.2010
- Author(s)
  Otani K, Kitayama J, Kamei, T, Soma D, Miyato H, Yamauchi T, Kadowaki T, Nagawa H
- Journal Title
  
  Journal of Gastroenterology
  
  Volume: 45 Pages: 918-927
- NAID
  10027698901
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390254
[Journal Article] Adiponectin suppresses tumorigenesis in Apc(Min)(/+) mice.2010
- Author(s)
  Otani K, Kitayama J, Yasuda K, Nio Y, Iwabu M, Okudaira S, Aoki J, Yamauchi T, Kadowaki T, Nagawa H
- Journal Title
  
  Cancer Letter 288(2)
  
  Pages: 177-182
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390254
[Journal Article] Adiponectin and AdipoR1 regulate PGC-1alpha and mitochondria by Ca(2+) and AMPK/SIRT1.2010
- Author(s)
  Iwabu M, Yamauchi T, Okada-Iwabu M, Sato K, Nakagawa T, Funata M, Yamaguchi M, Namiki S, Nakayama R, Tabata M, Ogata H, Kubota N, Takamoto I, Hayashi YK, Yamauchi N, Waki H, Fukayama M, Nishino I, Tokuyama K, Ueki K, Oike Y, Ishii S, Hirose K, Shimizu T, Touhara K, Kadowaki T.
- Journal Title
  
  Nature
  
  Volume: 464 Pages: 1313-1319
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22126007
[Journal Article] Adiponectin recceptors are downregulated in human gastric cancer.2010
- Author(s)
  Otani K, Kitayama J, Kamei T, Soma D, Miyato H, Yamauchi T, Kadowaki T, Nagawa H
- Journal Title
  
  J Gastroenterol.
  
  Volume: 45 Pages: 918-927
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20229008
[Journal Article] A genome-wide association study in the Japanese population identifies susceptibility loci for type 2 diabetes at UBE2E2 and C2CD4A-C2CD4B2010
- Author(s)
  Yamauchi T, Hara K, Maeda S, Yasuda K, Takahashi A, Horikoshi M, Nakamura M, Fujita H, Grarup N, Cauchi S, Ng DP, Ma RC, Tsunoda T, Kubo M, Watada H, Maegawa H, Okada-Iwabu M, Iwabu M, Shojima N, Shin HD, Andersen G, Witte DR, Jorgensen T, Lauritzen T, Sandbwk A, Hansen T, Ohshige T, Omori S, Saito I, Kaku K, Hirose H, So WY, Beury D, Chan JC, Park KS, Tai ES, Ito C, Tanaka Y, Kashiwagi A, Kawamori R, Kasuga M, Froguel P, Pedersen O, Kamatani N, Nakamura Y, Kadowaki T
- Journal Title
  
  Nature Genetics
  
  Volume: 42 Pages: 864-868
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390254
[Journal Article] Adiponectin suppresses tumorigenesis in Apc(Min)(/+) mice.2010
- Author(s)
  Otani K, Kitayama J, Yasuda K, Nio Y, Iwabu M, Okudaira S, Aoki J, Yamauchi T, Kadowaki T, Nagawa H.
- Journal Title
  
  Cancer Lett. 288
  
  Pages: 177-182
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659228
[Journal Article] Adiponectin and AdipoR1 regulate PGC-1α and mitochondria by Ca2+ and AMPK/SIRT12010
- Author(s)
  Iwabu, M., Yamauchi, T., Okada-Iwabu, M., Sato, K., Nakagawa, T., Funata, M., Yamaguchi, M., Namiki, S., Nakayama, R., Tabata, M., Ogata, H., Kubota, N.,Takamoto, I., Hayashi, YK., Yamauchi, N., Waki, H., Fukayama, M., Nishino, I., Tokuyama, K., Ueki, K., Oike, Y., Ishii, S., Hirose, K., Shimizu, T., Touhara, K., and Kadowaki, T
- Journal Title
  
  Nature
  
  Volume: 464 Issue: 7293 Pages: 1313-1319
- DOI
  10.1038/nature08991
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19002011, KAKENHI-PROJECT-20229008, KAKENHI-PROJECT-21390278, KAKENHI-PROJECT-21680035, KAKENHI-PROJECT-22790244
[Journal Article] Adiponectin and Adipo1 regulate PGC-1alpha and mitochondria by Ca(2+) and AMPK/SIRT1.2010
- Author(s)
  Iwabu M, Yamauchi T, Okada-Iwabu M, Sato K, Nakagawa T, Funata M, Yamaguchi M, Namiki S, Nakayama R, Tabata M, Ogata H, Kubota N, Takamoto I, Hayashi YK, Yamauchi N, Waki H, Fukayama M, Nishino I, Tokuyama K, Ueki K, Oike Y, Ishii S, Hirose K, Shimizu T, Touhara K, Kadowaki T.
- Journal Title
  
  Nature (published oline Mar.31,2010)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659228
[Journal Article] Adiponectin and AdipoR1 regulate PGC1・and mitochondria by Ca^<2+> and AMPK/SIRT1.2010
- Author(s)
  Iwabu M, Yamauchi T, Okada-Iwabu M, Sato K, Nakagawa T, Funata M, Yamaguchi M, Namiki S, Nakayama R, Tabata M, Ogata H, Kubota N, Takamoto I, Hayashi YK, Yamauchi N, Waki H, Fukayama M, Nishino I, Tokuyama K, Ueki K, Oike Y, Ishii S, Hirose K, Shimizu T, Touhara K, Kadowaki T
- Journal Title
  
  Nature 464
  
  Pages: 1313-1319
- Data Source
  KAKENHI-PROJECT-20229008
[Journal Article] Adiponectin and AdipoR1 regulate PGC-lalpha and mitochondria by Ca(2+) and AMPK/SIRT1.2010
- Author(s)
  Iwabu M, Yamauchi T, Okada-Iwabu M, Sato K, Nakagawa T, Funata M, Yamaguchi M, Namiki S, Nakayama R, Tabata M, Ogata H, Kubota N, Takamoto I, Hayashi YK, Yamauchi N, waki H, Fukayama M, Nishino I, Tokuyama K, Ueki K, Oike Y, Ishii S, Hirose K, Shimizu T, Touhara K, Kadowaki T.
- Journal Title
  
  Nature (published online Mar.31, 2010)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20229008
[Journal Article] Adiponectin suppresses hepatic SREBP1c expression in an AdipoR1/LKB1/AMPK dependent pathway.2009
- Author(s)
  Awazawa M, Ueki K, Inabe K, Yamauchi T, Kaneko K, Okazaki Y, Bardeesy N, Ohnishi S, Nagai R, Kadowaki T
- Journal Title
  
  Biochem Biophys Res Commun 382
  
  Pages: 51-56
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659228
[Journal Article] Reconsideration of insulin signals induced by improved laboratory animal diets, Japanese and American diets, in IRS-2 deficcient mice.2009
- Author(s)
  Hashimoto H, Arai T, Mori A, Kawai K, Hikishima K, Ohnishi Y, Eto T, Ito M, Hioki K, Suzuki R, Ohsugi M, Saito M, Ueyama Y, Okano H, Yamauchi T, Kubota N, Ueki K, Tobe K, Tamaoki N, Kadowaki T, Kosaka K
- Journal Title
  
  Exp Clin Endocrinol Diabetes 117
  
  Pages: 577-586
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390254
[Journal Article] Rimonabant ameliorates insulin resistance via both adiponectin-dependent and adiponectin-independent pathways2009
- Author(s)
  Watanabe T, Kubota N, Ohsugi M, Kubota T, Takamoto I, Iwabu M, Awazawa M, Katsuyama H, Hasegawa C, Tokuyama K, Moroi M, Sugi K, Yamauchi T, Noda T, Nagai R, Terauchi Y, Tobe K, Ueki K, Kadnwaki T
- Journal Title
  
  J Blot Chem 284
  
  Pages: 1803-1812
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390254
[Journal Article] Adiponectin suppresses hepatic SREBP1c expression in an AdipoRi/LKB1/AMPK dependent pathway.2009
- Author(s)
  Awazawa M, Ueki K, Inabe K, Yamauchi T, Kaneko K, Okazaki Y, Bardeesy N, Ohnishi S, Nagai R, Kadowaki T
- Journal Title
  
  Biochem Biophys Res Commun 382
  
  Pages: 51-56
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390254
[Journal Article] Adiponectin suppresses hepatic SREBP1c expression in an AdipoR1/LKB1/AMPK dependent pathway.2009
- Author(s)
  Awazawa M, Ueki K, Inabe K, Yamauchi T, Kanako K, Okazaki Y, Bardeesy N, Ohnishi S, Nagai R, Kadowaki T
- Journal Title
  
  Biochem Biophys Res Commun 382
  
  Pages: 51-56
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20229008
[Journal Article] Peroxisome proliferator-activated receptor gamma agonist rosiglitazone increases the expression of very low density lipoprotein receptor gene in adipocytes.2009
- Author(s)
  Takazawa T, Yamauchi T, Tsuchida A, Takata M, Hada Y, Iwabu M, Okada-Iwabu M, Ueki K, Kadowaki T
- Journal Title
  
  J Biol Chem 30
  
  Pages: 30049-30057
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20229008
[Journal Article] Rimonabant ameliorates insulin resistance vla both adiponectin-dependent and adiponectin-independent pathways.2009
- Author(s)
  Watanabe T, Kubota N, Ohsugi M, Kubota T, Takamoto I, Iwabu M, Awazawa M, Katsuyama H, Hasegawa C, Yamauchi T, Noda T,Nagai R, Tcrauchi Y, Tobe K, Ueki K, Kadowaki T
- Journal Title
  
  J. Biol. Chem 284
  
  Pages: 1803-1812
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591037
[Journal Article] Peroxisome proliferator-activated receptor γ agonist rosiglitazone increases expression of very low density lipoprotein receptor gene in adipocytes.2009
- Author(s)
  Takazawa T, Yamauchi T, Tsuchida A, Takata M, Hada Y, Iwabu M, Okada-Iwabu M, Ueki K, Kadowaki T
- Journal Title
  
  The Journal of Biological Chemistry 284
  
  Pages: 30049-30057
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390254
[Journal Article] Reconsideration of insulin signals induced by improved laboratory animal diets, Japanese and American diets, in IRS-2 deficcient mice.2009
- Author(s)
  Hashimoto H, Arai T, Mori A, Kawai K, Hikishima K, Ohnishi Y, Eto T, Ito M, Hioki K, Suzuki R, Ohsugi M, Saito M, Ueyama Y, Okano H, Yamauchi T, Kubota N, Ueki K, Tobe K, Tamaoki N, Kadowaki T, Kosaka K
- Journal Title
  
  Exp Clin Endocrinol Diabetes 117
  
  Pages: 577-586
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659228
[Journal Article] Adiponectin suppresses hepatic SREBP1c expression in an AdipoRl/LKB1/AMPK dependent pathway.2009
- Author(s)
  Awazawa M, Ueki K, Inane K, Yamauchi T, Kaneko K, Okazaki Y, Bardeesy N, Ohnishi S, Nagai R, Kadowaki T.
- Journal Title
  
  Biochem Biophys Res Commun (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390254
[Journal Article] Rimonabant amelio- rates insulin resistance via both adipo- nectin-dependent and adiponectin -independent pathways2009
- Author(s)
  atanabe T, Kubota N, Iwabu M, Yamauchi T, Ueki K, Kadowaki T
- Journal Title
  
  J.Biol.Chem.
  
  Volume: 284 Issue: 3 Pages: 1803-1812
- DOI
  10.1074/jbc.m807120200
- Data Source
  KAKENHI-PROJECT-20229008
[Journal Article] Adiponectin suppresses hepatic SREBP1c expression in an AdipoR1/LKB1/AMPK dependent pathway.2009
- Author(s)
  Awazawa M, Ueki K, Inabe K, Yamauchi T, Kaneko K, Okazaki Y, Bardeesy N, Ohnishi S, Nagai R, Kadowaki T
- Journal Title
  
  Biochemical and Biophysical Research Communications 382
  
  Pages: 51-56
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390254
[Journal Article] Peroxisome proliferator-activated receptor gamma agonist rosiglitazone increases the expression of very low density lipoprotein receptor gene in adipocytes.2009
- Author(s)
  Takazawa T, Yamauchi T, Tsuchida A, Takata M, Hada Y, Iwabu M, Okada-Iwabu M, Ueki K, Kadowaki T
- Journal Title
  
  J Biol Chem 284
  
  Pages: 30049-30057
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659228
[Journal Article] Rimonabant Ameliorates Insulin Resistance via both Adiponectin-dependent and Adiponectin-independent Pathways.2009
- Author(s)
  Watanabe T, Kubota N, Ohsugi M, Kubota T, Takamoto I, Iwabu M, Awazawa M, Katsuyama H, Hasegawa C, Tokuyama K, Moroi M, Sugi K, Yamauchi T, Noda T, Nagai R, Terauchi Y, Tobe K, Ueki K, Kadowaki T
- Journal Title
  
  The Journal of Biological Chemistry 284
  
  Pages: 1803-1812
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390254
[Journal Article] Peroxisome proliferator-activated receptor gamma agonist rosiglitazone increases the expression of very low density lipoprotein receptor gene in adipocytes.2009
- Author(s)
  Takazawa T, Yamauchi T, Tsuchida A, Takata M, Hada Y, Iwabu M, Okada-Iwabu M, Ueki K, Kadowaki T
- Journal Title
  
  J Biol Chem 284
  
  Pages: 30049-30057
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390254
[Journal Article] Peroxisome proliferator-activated receptor gamma agonist rosiglitazone increases the expression of very low density lipoprotein receptor gene in adipocytes2009
- Author(s)
  Takazawa T, Yamauchi T, Iwabu M, Okada-Iwabu M, Ueki K, Kadowaki T
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 284 Pages: 30049-30057
- Data Source
  KAKENHI-PROJECT-20229008
[Journal Article] Reconsideration of insulin signals induced by improved laboratory animal diets, Japanese and American diets, in IRS-2 deficcient mice.2009
- Author(s)
  Hashimoto H, Arai T, Mori A, Kawai K, Hikishima K, Ohnishi Y, Eto T, Ito M, Hioki K, Suzuki R, Ohsugi M, Saito M, Ueyama Y, Okano H, Yamauchi T, Kubota N, Ueki K, Tobe K, Tamaoki N, Kadowaki T, Kosaka K
- Journal Title
  
  Exp Clin Endocrinol Diabetes 117
  
  Pages: 577-86
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20229008
[Journal Article] TamaokiN, Nomura T, Kosaka K. An Efficient reproductive method for Irs2-/- micewith C57BL/6JJcl genetic background2008
- Author(s)
  Hashimoto H, Eto T, Kamisako T, Hoya N,Hatakeyama T, Arai T, Yokosuka M,Ohnishi Y, Ito M, Hioki K, Suzuki R,Ohsugi M, Saito M, Ueyama Y, YamauchiT, Kubota N, Tobe K, Kadowaki T.
- Journal Title
  
  Exp. Anim. 57
  
  Pages: 407-411
- Data Source
  KAKENHI-PROJECT-19591037
[Journal Article] The physiological and pathophysiological role of adiponectin and adiponectin receptors in the peripheral tissues and CNS.2008
- Author(s)
  Kadowaki T, Yamauchi T, Kubota N.
- Journal Title
  
  FEBS Lett. 582
  
  Pages: 74-80
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15081202
[Journal Article] Adiponectin suppresses colorectal carcinogenesis under the high-fat diet condition.2008
- Author(s)
  Fujisawa T, Endo H, Tomimoto A, Sugiyama M, Takahashi H, Saito S, Inamori M, Nakajima N, Watanabe M, Kubota N, Yamauchi T, Kadowaki T, Wada K, Nakagama H, Nakajima A
- Journal Title
  
  Gut 57
  
  Pages: 1531-1538
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390254
[Journal Article] Fulminant type 1 diabetes mellitus observed in insulin receptor substrate 2 deficient mice2008
- Author(s)
  Arai T, Hashimoto H, Kawai K, Mori A, Ohnishi Y, Hioki K, Ito M, Sito M, Ueyama Y, Ohsugi M, Suzuki R, Kubota N, Yamauchi T, Tobe K, Kadowaki T, Kosaka K
- Journal Title
  
  Clin Exp Med 8
  
  Pages: 93-99
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20229008
[Journal Article] Thephysiological and pathophysiologicalrole of adiponectin and adiponectinreceptors in the peripheral tissues and CNS2008
- Author(s)
  Kadowaki T, Yamauchi T, Kubota N.
- Journal Title
  
  FEBS Lett. 582
  
  Pages: 74-80
- Data Source
  KAKENHI-PROJECT-19591037
[Journal Article] The physiological and pathophysiological role of adiponectin and adiponectin receptors in the peripheral tissues and CNS2008
- Author(s)
  Kadowaki T, Yamauchi T, Kuhota N.
- Journal Title
  
  FEBS Lett 582
  
  Pages: 74-80
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390270
[Journal Article] Adiponectin suppresses colorectal carcinogenesis under the high-fat diet condition2008
- Author(s)
  Fujisawa T, Kubota N, Yamauchi T, Kadowaki T
- Journal Title
  
  Gut
  
  Volume: 57 Issue: 11 Pages: 1531-1538
- DOI
  10.1136/gut.2008.159293
- Data Source
  KAKENHI-PROJECT-20229008
[Journal Article] Adiponectin suppresses colorectal carcinogenesis under the high-fat diet condition2008
- Author(s)
  Fujisawa T, Endo H, Tomimoto A, Sugiyama M, Takahashi H, Saito S, Inamori M,nakajima N, Watanabe M, Kubota N, Yamauchi T, Kadowaki T, Wada K, Nakagama H, Nakajima A.
- Journal Title
  
  Gut 57
  
  Pages: 1531-1538
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20229008
[Journal Article] An Efficient reproductive method for Irs2-/-mice with C57BL/6JJclgenetic background.2008
- Author(s)
  Hashimoto H, Eto T, Kamisako T, Hoya N, Hatakeyama T, Arai T, Yokosuka M, Ohnishi Y, Ito M, Hioki K, Suzuki R, Ohsugi M, Saito M, Ueyama Y, Yamauchi T, Kubota N, Tobe K, Kadowaki T, Tamaoki N, Nomura T, Kosaka K.
- Journal Title
  
  Exp Anim 57
  
  Pages: 407-411
- NAID
  10024166620
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390254
[Journal Article] The physiological and pathophysiological role of adiponectin and adipone ctin receptors in the peripheral tissues and CNS.2008
- Author(s)
  Kadowaki T, Yamauchi T, Kubota N.
- Journal Title
  
  FEBS Lett. 582
  
  Pages: 74-80
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15081202
[Journal Article] 5-Hydroxytryptamine 2A receptor signaling cascade modulates adiponectin and plasminogen activator inhibitor 1 expression in adipose tissue.2008
- Author(s)
  Uchida-Kitajima S, Yamauchi T, Takashina Y, Okada-Iwabu M, Iwabu M, Ueki K, Kadowaki T.
- Journal Title
  
  FEBS Lett 582
  
  Pages: 3037-3044
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390254
[Journal Article] Adiponectin Suppresses Colorectal Carcinogenesis under the High-fat Diet Condition.2008
- Author(s)
  Fujisawa T, Endo H, Tomimoto A, Sugiyama M, Takahashi H, Saito S, Inamori M, Nakajima N, Watanabe M, Kubota N, Yamauchi T, Kadowaki T, Wada K, Nakagame H, Nakajima A
- Journal Title
  
  Gut 57
  
  Pages: 1531-1538
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591037
[Journal Article] The physiological and pathophysiological role of adiponectin and adiponectin receptoiCs in the peripheral tissues and CNS2008
- Author(s)
  Kadowaki T, Yamauchi T, Kubota N.
- Journal Title
  
  FEBS Lett 582
  
  Pages: 74-80
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209033
[Journal Article] AdiponectinSuppresses Colorectal Carcinogenesis under the High-fat Diet Condition2008
- Author(s)
  Fujisawa T, Endo H, Tomimoto A, SugiyamaM, Takahashi H, Saito S, Inamori M,Nakajima N, Watanabe M, Kubota N,Yamauchi T, Kadowaki T, Wada K,Nakagama H, Nakajima A.
- Journal Title
  
  Gut 57
  
  Pages: 1531-1538
- Data Source
  KAKENHI-PROJECT-19591037
[Journal Article] An Efficient reproductive method for Irs2-/- mice with C57BL /6 Jcl genetic background.2008
- Author(s)
  Hashimoto H, Eto T, Kamisako T, Hoya N, Hatakeyama T, Arai T, Yokosuka M, Ohnishi Y, Ito M, Hioki K, Suzuki R, Ohsugi M, Saito M, Ueyama Y, Yamauchi T, Kubota N, Tobe K, Kadowaki T, Tamaoki N, Nomura T
- Journal Title
  
  Exp. Anim. 57
  
  Pages: 407-411
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591037
[Journal Article] Adiponectin suppresses colorectal carcinogenesis under the high-fat diet condition.2008
- Author(s)
  Fujisawa T, Endo H, Tomimoto A, Sugiyama M, Takahashi H, Saito S, Inamori M, Nakajima N, Watanabe M, Kubota N, Yamauchi T, Kadowaki T, Wada K, Nakagama H, Nakajima A.
- Journal Title
  
  Gut 57
  
  Pages: 1531-1538
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390254
[Journal Article] Fulminant type 1 diabetes mellitus observed in insulin receptor substrate 2 deficient mice2008
- Author(s)
  Arai T, Hashimoto H, Kawai K, Mori A, Ohnishi Y, Hioki K, Ito M, Saito M, Ueyama Y, Ohsugi M, Suzuki R, Kubota N, Yamauchi T, Tobe K. Kadowaki T, Kosaka K.
- Journal Title
  
  Clin Exp Med 8
  
  Pages: 93-99
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390254
[Journal Article] 5-Hydroxytryptamine 2A receptor signaling cascade modulates adiponectin and plasminogen activator inhibitor 1 expression in adipose tissue.2008
- Author(s)
  Uchida-Kitajima S, Yamauchi T, Takashina Y, Okada-Iwabu M, Iwabu M, Ueki K, Kadowaki T
- Journal Title
  
  FEBS Letters 582
  
  Pages: 3037-3044
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390254
[Journal Article] The physiological and pathophysiological role of adiponectin and adiponectin receptors in the peripheral tissues and CNS2008
- Author(s)
  Kadowaki T, Yamauchi T, Kubota N.
- Journal Title
  
  FEBS Lett. 582
  
  Pages: 74-80
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15081202
[Journal Article] Phenotypes of IRS-2 deficient mice produced by reproductive technology are stable2007
- Author(s)
  Hashimoto H, Arai T, Ohnishi Y, Eto T, Ito M, Hioki K, Suzuki R, Yamauchi T, Ohsugi M, Saito M, Ueyama Y, Tobe K, Kadowaki T, Tamaoki N, Kosaka K.
- Journal Title
  
  Exp Anim 56
  
  Pages: 149-154
- NAID
  130000068045
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18209033
[Journal Article] Targeted disruption of AdipoR1 and AdipoR2 causes abrogation of adiponectin binding and metabolic actions.2007
- Author(s)
  Yamauchi T, Kubota N, Kadowaki T.
- Journal Title
  
  Nature Medicine 13(3)
  
  Pages: 332-339
- Data Source
  KAKENHI-PROJECT-18209033
[Journal Article] Adiponectin stimulates AMP-activated protein kinase in the hypothalamus and increases food intake.2007
- Author(s)
  Kubota N, Yano W, Kubota T, Yamauchi T, Itoh S, Kumagai H, Kozono H, Takamoto I, Okamoto S, Shiuchi T, Suzuki R, Satoh H, Tsuchida A, Moroi M, Sugi K, Noda T, Ebinuma H, Ueta Y, Kondo T, Araki E, Ezaki O, Nagai R, Tobe K, Terauchi Y, Ueki K, Minokoshi Y, Kadowaki T.
- Journal Title
  
  Cell Metab. 6
  
  Pages: 55-68
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390270
[Journal Article] Adiponectin stimulates AMP-activated protein kinase in the hypothalamus and increases food intake.2007
- Author(s)
  Kubota N, Yano W, Kubota T, Yamauchi T, Itoh S, Kumagai H, Kozono H, Takamoto I, Okamoto S, Shiuchi T, Suzuki R, Satoh H, Tsuchida A, Moroi M, Sugi K, Noda T, Ebinuma H, Ueta Y, Kondo T, Araki E, Ezaki O, Nagai R, Tobe K, Terauchi Y, Ueki K, Minokoshi Y, Kadowaki T.
- Journal Title
  
  Cell Metab. 6
  
  Pages: 55-68
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15081202
[Journal Article] Phenotypes of IRS-2 deficient mice produced by reproductive technology are stable2007
- Author(s)
  Hashimoto H, Arai T, Ohnishi Y, Eto T, Ito M, Hioki K, Suzuki R, Yamauchi T, Ohsugi M, Saito M, Ueyama Y, Tobe K, Kadowaki T, Tamaoki N, Kosaka K.
- Journal Title
  
  Exp Anim. 56
  
  Pages: 149-154
- NAID
  130000068045
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390270
[Journal Article] Targeted disruption of AdipoR1 and AdipoR2 causes abrogation of adiponectin binding and metabolic actions.2007
- Author(s)
  Yamauchi T, Nio Y, Maki T, Kobayashi M, Takazawa T, Iwabu M, Okada-Iwabu M, Kawamoto S, Kubota N, Kubota T, Ito Y, Kamon J, Tsuchida A, Kumagai K, Kozono H, Hada Y, Ogata H, Tokuyama K, Tsunoda M, Ide T, Murakami K, Awazawa M, Takamoto I, Froguel P, Hara K,Tobe K,Nagai R,Ueki K,Kadowaki T.
- Journal Title
  
  Nat Med. 13
  
  Pages: 332-339
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390270
[Journal Article] Adiponectin stimulates AMP-activated protein kinase in the hypothalam us and increases food intake.2007
- Author(s)
  Kubota N, Yano W, Kubota T, Yamauchi T, Itoh S, Kumagai H, Kozono H, Takamoto I, Okamoto S, Shiuchi T, Suzuki R, Satoh H, Tsuchida A, Moroi M, Sugi K, Noda T, Ebinuma H, Ueta Y, Kondo T, Araki E, Ezaki O, Nagai R, Tobe K, Terauchi Y, Ueki K, Minokoshi Y,
- Journal Title
  
  Cell Metab. 6
  
  Pages: 55-68
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209033
[Journal Article] Adiponectin inhibits the growth and peritoneal metastasis of gastric cancer through its specific membrane receptors AdipoR1 and AdipoR2.2007
- Author(s)
  Ishikawa M, Kitayama J, Yamauchi T, Kadowaki T, Maki T, Miyato H, Yamashita H, Nagawa H.
- Journal Title
  
  Cancer Sci. 98
  
  Pages: 1120-1127
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209033
[Journal Article] Targeted disruption of AdipoR1 and Adipo2 causes abrogation of adiponectin binding and metabolic actions.2007
- Author(s)
  Yamauchi T, et al.
- Journal Title
  
  Nat Med 13(3)
  
  Pages: 332-339
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390260
[Journal Article] Adiponectin inhibits the growth and peritoneal metastasis of gastric cancer through its specific membrane receptors AdipoRl and AdipoR22007
- Author(s)
  Ishikawa M, Kitayama J, Yamauchi T, Kadowaki T, Maki T, Miyato H, Yamashita H, Nagawa H.
- Journal Title
  
  Cancer Sci. 98
  
  Pages: 1120-1127
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18209033
[Journal Article] Adiponectin stimulates AMP-activated protein kinase in the hypothalamus and increases food intake2007
- Author(s)
  Kubota N, Yano W, Kubota T, Yamauchi T, Itoh S, Kumagai H, Kozono H, Takamoto I, Okamoto S, Shiuchi T, Suzuki R, Satoh H, Tsuchida A, Moroi M, Sugi K, Noda T, Ebinuma H, Ueta Y, Kondo T, Araki E, Ezaki O, Nagai R, Tobe K, Terauchi Y, Ueki K, Mimokoshi Y, Ueki K,Minokoshi Y,Kadowaki T.
- Journal Title
  
  CeU Metab 6
  
  Pages: 55-68
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209033
[Journal Article] Adiponectin inhibits the growth and peritoneal metastasis of gastric cancer through its specific membrane receptors AdipoR1 and AdipoR2.2007
- Author(s)
  Ishikawa M, Kitayama J, Yamauchi T, Kadowaki T, Maki T, Miyato H, Yamashita H, Nagawa H.
- Journal Title
  
  Cancer Sci. 98
  
  Pages: 1120-1127
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390270
[Journal Article] Adiponectin inhibits the growth and peritoneal metastasis of gastric cancer through its specific membrane receptors AdipoR1 and AdipoR22007
- Author(s)
  Ishikawa M, Kitayama J, Yamauchi T, Kadowaki T, Maki T, Miyato H, Yamashita H, Nagawa H.
- Journal Title
  
  Cancer Sci. 98
  
  Pages: 1120-1127
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15081202
[Journal Article] Improved ELISA for selectivemeasurement of adiponectin multimersand identification of adiponectin inhuman cerebrospinal fluid.2007
- Author(s)
  Ebinuma H, Miida T, Yamauchi T, HadaY, Hara K, Kubota N, Kadowaki T.
- Journal Title
  
  Clin. Chem 53
  
  Pages: 1541-1544
- Data Source
  KAKENHI-PROJECT-19591037
[Journal Article] Improved ELISA for selective measurement of adiponectin multimers and identification of adiponectin in human cerebrospinal fluid2007
- Author(s)
  Ebinuma H, Miida T, Yamauchi T, Hada Y, Hara K, Kubota N, Kadowaki T.
- Journal Title
  
  Clin Chem. 53
  
  Pages: 1541-1544
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15081202
[Journal Article] Targeted disruption of AdipoR1 and AdipoR2 causes abrogation of adiponectin binding and metabolic actions.2007
- Author(s)
  Yamauchi T, Kubota N, Kadowaki T.
- Journal Title
  
  Nature Medicine 13(3)
  
  Pages: 332-339
- Data Source
  KAKENHI-PROJECT-18390270
[Journal Article] Improved ELISA for selective measurement of adiponectin multimers and identification of adiponectin in human cerebrospinal fluid.2007
- Author(s)
  Ebinuma H, Miida T, Yamauchi T, Hada Y, Hara K, Kubota N, Kadowaki T.
- Journal Title
  
  Clin Chem. 53
  
  Pages: 1541-1544
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209033
[Journal Article] Adiponectin inhibits the growth and peritoneal metastasis of gastric cancer through its specific membrane receptors AdipoR1 and AdipoR22007
- Author(s)
  Ishikawa M, Kitayama J, Yamauchi T, Kadowaki T, Maki T, Miyato H, Yamashita H, Nagawa H.
- Journal Title
  
  Cancer Sci. 98
  
  Pages: 1120-1127
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390270
[Journal Article] Phenotypes of IRS-2 deficient mice produced by reproductive technology are stable2007
- Author(s)
  Hashimoto H, Arai T, Ohnishi Y, Eto T, Ito M, Hioki K, Suzuki R, Yamauchi T, Ohsugi M, Saito M, Ueyama Y, Tobe K, Kadowaki T, Tamaoki N, Kosaka K.
- Journal Title
  
  Exp Anim 56
  
  Pages: 149-154
- NAID
  130000068045
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390270
[Journal Article] Improved EHSA for selective measmement of adiponectin multimers and identification of adipollectin in human cerebrospinal fluid2007
- Author(s)
  Ebinuma H, Miida T, Yamauchi T, Hada Y, Hara K, Kubota N, Kadowaki T.
- Journal Title
  
  Clin Chem 53
  
  Pages: 1541-1544
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209033
[Journal Article] Adiponectin inhibits the growth and peritoneal metastasis of gastric cancer through its specific membrane receptors AdipoR1 and AdipoR2.2007
- Author(s)
  Ishikawa M, Kitayama J, Yamauchi T, Kadowaki T, Maki T, Miyato H, Yamashita H, Nagawa H.
- Journal Title
  
  Cancer Sci. 98
  
  Pages: 1120-1127
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15081202
[Journal Article] Phenotypes of IRS-2 deficient mice produced by reproductive technology are stable2007
- Author(s)
  Hashmoto H, Arai T, Ohnishi Y, Eto T, Ito M, Hioki K, Suzuki R, Yamauchi T, Ohsugi M, Saito M, Ueyama Y, Tobe K, Kadowaki T, Tamaoki N, Kosaka K.
- Journal Title
  
  Exp Anim 56
  
  Pages: 149-154
- NAID
  130000068045
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209033
[Journal Article] Improved ELISA for selective measurement of adiponectin multimers and identification of adiponectin in human cerebrospinal fluid2007
- Author(s)
  Ebinuma H, Miida T, Yamauchi T, Hada Y, Hara K, Kubota N, Kadowaki T.
- Journal Title
  
  Clin Chem. 53
  
  Pages: 1541-1544
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390270
[Journal Article] Targeted disruption of AdipoR1 and, Adipo2 causes abrogation of adiponectin binding and metabolic actions.2007
- Author(s)
  Yamauchi T, et al.
- Journal Title
  
  Nat Med 13(3)
  
  Pages: 332-339
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390260
[Journal Article] Phenotypes of IRS-2 deficient mice produced by reproductive technology are stable. Exp Anim. 56 : 149-154, 20072007
- Author(s)
  Hashimoto H, Arai T, Ohnishi Y, Eto T, Ito M, Hioki K, Suzuki R, Yamauchi T, Ohsugi M, Saito M, Ueyama Y, Tobe K, Kadowaki T, Tamaoki N, Kosaka K.
- Journal Title
  
  Exp Anim. 56
  
  Pages: 149-154
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15081202
[Journal Article] Targeted disruption ofAdipoR1 and AdipoR2 causes abrogation of adiponectin binding and metabolic actions2007
- Author(s)
  Yamauchi T, Nio Y, Maki T, Kobayashi M, Takazawa T, Iwabu M, Okada-Iwabu M, Kawamoto S, Kubota N, Kubota T, Ito Y, Kamon J, Tsuchida A, Kumagai K, Kozono H, Hada Y, Ogata H, Tokuyama K, Tsunoda M, Ide T, Murakami K, Awazawa M, Takamoto I, Froguel P, Hara K, Tobe K, Nagai R, Ueki K, Kadowaki T.
- Journal Title
  
  Nat Med. 13
  
  Pages: 322-339
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18209033
[Journal Article] Adiponectin inhibits the growth and peritoneal metastasis of gastric cancer through its specific membrane receptors AdipoRI and AdipoR22007
- Author(s)
  Ishikawa M, Kitayama J, Yamauchi T, Kadowaki T, Maki T, Miyato H, Yamashita H, Nagawa H.
- Journal Title
  
  Cancer Sci 98
  
  Pages: 1120-1127
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209033
[Journal Article] Improved EHSA for selective measurement of adiponectin multimers and identification of adiponectin in human cerebrospinal fluid2007
- Author(s)
  Ebinuma H, Miida T, Yamauchi T, Hada Y, Hara K, Kubota N, Kadowaki T.
- Journal Title
  
  Clin Chem 53
  
  Pages: 1541-1544
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390270
[Journal Article] Selective purification and characterization of adiponectin multimer species from human pasma.2007
- Author(s)
  Hada Y, Yamauchi T, Waki H, Tsuchida A, Hara K, Yago H, Miyazaki O, Ebinuma H, Kadowaki T.
- Journal Title
  
  Biochem Biophys Res Commun. 356(2)
  
  Pages: 487-493
- Data Source
  KAKENHI-PROJECT-17390260
[Journal Article] Adiponectin stimulates AMP-activated protein kinase in the hypothalamus and increases food intake.2007
- Author(s)
  Kubota N, Yano W, Kubota T, Yamauchi T, Itoh S, Kumagai H, Kozono H, Takamoto I, Okamoto S, Shiuchi T, Suzuki R, Satoh H, Tsuchida A, Moroi M, Sugi K, Noda T, Ebinuma H, Ueta Y, Kondo T, Araki E, Ezaki O, Nagai R, Tobe K, Terauchi Y, Ueki K, Minokoshi Y,Kadowaki,T
- Journal Title
  
  Cell Metab. 6
  
  Pages: 55-68
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15081202
[Journal Article] Targeted disruption of AdipoRl and AdipoR2 causes abrogation of adiponectin binding and metabohc actions2007
- Author(s)
  Yamauchi T, Nio Y, Maki T, Kobayashi M, Takazawa T, Iwabu M, Okada-Iwabu M, Kawamoto S, Kubota N, Kubota T, Ito Y, Kamon J, Tsuchida A, Kumagai K, Kozono H, Hada Y, Ogata H, Tbkuyama K, Tsunoda M, Ide T, Murakami K, Awazawa M, Takamoto I, Froguel P, Hara K, Tobe K, Nagai R, Ueki K, Kadowaki T.
- Journal Title
  
  Nat Med 13
  
  Pages: 332-339
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209033
[Journal Article] Improved ELISA for selective measurement of adiponectin multimers and identification of adiponectin in human cerebrospinal fluid.2007
- Author(s)
  Ebinuma H, Miida T, Yamauchi T, Hada Y, Hara K, Kubota N, Kadowaki T.
- Journal Title
  
  Clin Chem. 53
  
  Pages: 1541-1544
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390270
[Journal Article] Adiponectin inhibits the growth and peritoneal metastasis of gastric cancer through its specfic membrane receptors Adipol and AdipoR22007
- Author(s)
  Ishikawa M, Kitayama J, Yamauchi T, Kadowaki T, Maki T, Miyato H, Yamashita H, Nagawa H.
- Journal Title
  
  Cancer Sci 98
  
  Pages: 1120-1127
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390270
[Journal Article] Improved ELISA for selective measurement of adiponectin multimers and identification of adiponectin in human cerebrospinal fluid.2007
- Author(s)
  Ebinuma H, Miida T, Yamauchi T, Hada Y, Hara K, Kubota N, Kadowaki T.
- Journal Title
  
  Clin Chem. 53
  
  Pages: 1541-1544
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15081202
[Journal Article] Targeted disruption of AdipoR1 and Adipo2 causes abrogation of adiponectin binding and metabolic actions.2007
- Author(s)
  Yamauchi T, Nio Y, Maki T, Kobayashi M, Takazawa T, Iwabu M, Okada-Iwabu M, Kawamoto S, Kubota N, Kubota T, Ito Y, Kamon J, Tsuchida A, Kumagai K, Kozono H, Hada Y, Ogata H, Tokuyama K, Tsunoda M, Ide T, Murakami K, Awazawa M, Takamoto I, Froguel P, Hara K, Tobe K, Nagai R, Ueki K, Kadowaki T.
- Journal Title
  
  Nat Med. 13(3)
  
  Pages: 332-339
- Data Source
  KAKENHI-PROJECT-17390260
[Journal Article] Targeted disruption of AdipoRl and AdipoR2 causes abrogation of adiponectin binding and metabolic actions2007
- Author(s)
  Yamauchi T, Nio Y, Maki T, Kobayashi M, Takazawa T, Iwabu M, Okada-Iwabu M, Kawamoto S, Kubota N, Kubota T, Ito Y, Kamon J, Tsuchida A, Kumagai K, Kozono H, Hada Y, Ogata H, Tokuyama K, Tsunoda M, Ide T, Murakami K, Awazawa M, Takamoto I, Froguel P, Hara K, Tobe K, Nagai R, Ueki K, Kadowaki T.
- Journal Title
  
  Nat Med. 13
  
  Pages: 332-339
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390270
[Journal Article] Targeted disruption of AdipoR1 and AdipoR2 causes abrogation of adiponectin binding and metabolic actions.2007
- Author(s)
  Yamauchi T, Kubota N, Kadowaki T.
- Journal Title
  
  Nature Medicine 13(3)
  
  Pages: 332-339
- Data Source
  KAKENHI-PROJECT-15081202
[Journal Article] Phenotypes of IRS-2 deficient mice produced by reproductive technology are stable.2007
- Author(s)
  Hashimoto H, Arai T, Ohnishi Y, Eto T, Ito M, Hioki K, Suzuki R, Yamauchi T, Ohsugi M, Saito M, Ueyama Y, Tobe K, Kadowaki T, Tamaoki N, Kosaka K.
- Journal Title
  
  Exp Anim. 56
  
  Pages: 149-154
- NAID
  130000068045
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209033
[Journal Article] Improved ELISA for selective measurement of adiponectin multimers and identification of adiponectin in human cerebrospinal fluid2007
- Author(s)
  Ebinuma H, Miida T, Yamauchi T, Hada Y, Hara K, Kubota N, Kadowaki T.
- Journal Title
  
  Clim Chem 53
  
  Pages: 1541-1544
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18209033
[Journal Article] Adiponectin stimulates AMP-activated protein kinase in the hypothalamus and increases food intake2007
- Author(s)
  Kubota N, Yano W, Kubota T, Yamauchi T, Itoh S, Kumagai H, Kozono H, Takamoto I, Okamoto S, Shiuchi T, Suzuki R, Satoh H, Tsuchida A, Moroi M, Sugi K, Noda T, Ebinuma H, Ueta Y, Kondo T, Araki E, Ezaki O, Nagai R, Tobe K, Terauchi Y, Ueki K, Minokoshi Y, Kadowaki T.
- Journal Title
  
  Cell Metab. 6
  
  Pages: 55-68
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390270
[Journal Article] Adiponectin stimulates AMP-activated protein kinase in the hypothalamus and increases food intake2007
- Author(s)
  Kubota N, Yano W, Kubota T, Yamauchi T, Itoh S, Kumagai H, Kozono H, Takamoto I, Okamoto S, Shiuchi T, Suzuki R, Satoh H, Tsuchida A, Moroi M, Sugi K, Noda T, Ebinuma H, Ueta Y, Kondo T, Araki E, Ezaki O, Nagai R, Tobe K, Terauchi Y, Ueki K, Minokoshi Y, Kadowaki T.
- Journal Title
  
  Cell Metab 6
  
  Pages: 55-68
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18209033
[Journal Article] Adiponectin stmulates AMP-activated protein kinase in the hypothalam us and increases food intake2007
- Author(s)
  Kubota N, Yano W, Kubota T, Yamauchi T, Itoh S, Kumagai H, Kozono H, Takamoto I, Okamoto S, Shiuchi T, Suzuki R, Satoh H, Tsuchida A, Moroi M, Sugi K, Noda T, Ebinuma H, Ueta Y, Kondo T, Araki E, Ezaki O, Nagai R, Tobe K, Terauchi Y, Ueki K, Minokoshi Y,Kadowaki T.
- Journal Title
  
  Cell Metab 6
  
  Pages: 55-68
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390270
[Journal Article] Targeted disruption of AdipoR1 and AdipoR2 causes abrogation of adiponectin binding and metabolic actions.2007
- Author(s)
  Yamauchi T, Nio Y, Maki T, Kobayashi M, Takazawa T, Iwabu M, Okada-Iwabu M, Kawamoto S, Kubota N, Kubota T, Ito Y, Kamon J, Tsuchida A, Kumagai K, Kozono H, Hada Y, Ogata H, Tokuyama K, Tsunoda M, Ide T, Murakami K, Awazawa M, Takamoto I, Froguel P, Hara
- Journal Title
  
  Nat Med. 13
  
  Pages: 332-339
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209033
[Journal Article] Phenotypes of IRS-2 deficient mice produced by reproductive technology are stable.2007
- Author(s)
  Hashimoto H, Arai T, Ohnishi Y, Eto T, Ito M, Hioki K, Suzuki R, Yamauchi T, Ohsugi M, Saito M, Ueyama Y, Tobe K, Kadowaki T, Tamaoki N, Kosaka K.
- Journal Title
  
  Exp Anim. 56
  
  Pages: 149-154
- NAID
  130000068045
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15081202
[Journal Article] Adiponectin Stimulates AMP-ActivatedProtein Kinase in the Hypothalamus andIncreases Food Intake.2007
- Author(s)
  Kubota N, Yano W, Kubota T, YamauchiT, Itoh S, Kumagai H, Kozono H, TakamotoI, Okamoto S, Shiuchi T, Suzuki R, SatohH, Tsuchida A, Moroi M, Sugi K, Noda T,Ebinuma H, Ueta Y, Kondo T, Araki E,Ezaki O, Nagai R, Tobe K, Terauchi Y,Ueki K, Minokoshi Y, Kadowaki T
- Journal Title
  
  Cell Metab 6
  
  Pages: 55-68
- Data Source
  KAKENHI-PROJECT-19591037
[Journal Article] Targeted disruption of AdipoR1 and AdipoR2 causes abrogation of adiponectin binding and metabolic actions.2007
- Author(s)
  Yamauchi T, Kubota N, Kadowaki T
- Journal Title
  
  Nature Medicine 13(3)
  
  Pages: 332-339
- Data Source
  KAKENHI-PROJECT-18659265
[Journal Article] Phenotypes of IRS-2 deficient mice produced by reproductive technology are stable.2007
- Author(s)
  Hashimoto H, Arai T, Ohnishi Y, Eto T, Ito M, Hioki K, Suzuki R, Yamauchi T, Ohsugi M, Saito M, Ueyama Y, Tobe K, Kadowaki T, Tamaoki N, Kosaka K.
- Journal Title
  
  Exp Anim. 56
  
  Pages: 149-154
- NAID
  130000068045
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390270
[Journal Article] Phenotypes of IRS-2 deficient mice produced by reproductive technologyare stable.2007
- Author(s)
  Hashimoto H, Arai T, Ohnishi Y, Eto T, Ito M, Hioki K, Suzuki R, Yamauchi T, Ohsugi M, Saito M, Ueyama Y, Tobe K, Kadowaki T, Tamaoki N, Kosaka K.
- Journal Title
  
  Exp Anim. 56
  
  Pages: 149-154
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15081202
[Journal Article] Adiponectin stimulates AMP- activated protein kinase in the hypothalamus and increases food intake2007
- Author(s)
  Kubota N, Yano W, Kubota T, Yamauchi T, Itoh S, Kumagai H, Kozono H, Takamoto I, Okamoto S, Shiuchi T, Suzuki R, Satoh H, Tsuchida A, MoroiM, Sugi K, Noda T, Ebinuma H, Ueta Y, Kondo T, Araki E, Ezaki o, Nagai R, Tobe K, Terauchi Y Ueki K, Minokoshi Y Kadowaki T.
- Journal Title
  
  Cell Metab. 6
  
  Pages: 55-68
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15081202
[Journal Article] Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome.2006
- Author(s)
  Kadowaki T, Yamauchi T, Kubota N, et al.
- Journal Title
  
  J. Clin. Invest. 116
  
  Pages: 1784-1792
- Data Source
  KAKENHI-PROJECT-15081202
[Journal Article] Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome.2006
- Author(s)
  Kadowaki T, Yamauchi T, Kubota N, et al.
- Journal Title
  
  J. Clin. Invest. 116
  
  Pages: 1784-1792
- Data Source
  KAKENHI-PROJECT-18209033
[Journal Article] Adiponectin-dependent and - independent pathways in insulin-sensitizing and antidiabetic actions of thiazolidinedions.2006
- Author(s)
  Kubota N, Yamauchi T, Tobe K, Kadowaki T.
- Journal Title
  
  Diabetes. 55 Suppl 2
- Data Source
  KAKENHI-PROJECT-17390260
[Journal Article] Overexpression of MCP-1 in adipose tissues causes macrophage recruitment and insulin resistance.2006
- Author(s)
  Kubota N, Yamauchi T, Kadowaki T.
- Journal Title
  
  J. Biol. Chem. 281
  
  Pages: 26602-26614
- Data Source
  KAKENHI-PROJECT-18209033
[Journal Article] Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome.2006
- Author(s)
  Kadowaki T, Yamauchi T, Kubota N, et al.
- Journal Title
  
  J. Clin. Invest. 116
  
  Pages: 1784-1792
- Data Source
  KAKENHI-PROJECT-18659265
[Journal Article] Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome.2006
- Author(s)
  Kadowaki T, Yamauchi T, Kubota N, et al.
- Journal Title
  
  J. Clin. Invest. 116
  
  Pages: 1784-1792
- Data Source
  KAKENHI-PROJECT-18390270
[Journal Article] Overexpression of MCP-1 in adipose tissues causes macrophage recruitment and insulin resistance.2006
- Author(s)
  Kubota N, Yamauchi T, Kadowaki T.
- Journal Title
  
  J. Biol. Chem. 281
  
  Pages: 26602-26614
- Data Source
  KAKENHI-PROJECT-15081202
[Journal Article] Adiponectin-dependent and -independent pathways in insulin-sensitizing and antidiabetic actions of thiazolidinediones2006
- Author(s)
  Kubota N, Yamauchi T, Tobe K, Kadowaki, T
- Journal Title
  
  Diabetes 55
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390270
[Journal Article] Measurement of the high- molecular- weight form of adiponectin in plasma is useful for the prediction of insulin resistance and metabolic syndrome.2006
- Author(s)
  Hara K, Horikoshi M, Yamauchi T, Yago H, Miyazaki O, Ebinuma H, Imai Y, Nagai R, Kadowaki T.
- Journal Title
  
  Diabetes Care 29
  
  Pages: 1357-1362
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209033
[Journal Article] Overexpression of MCP-1 in adipose tissues causes macrophage recruitment and insulin resistance.2006
- Author(s)
  Kubota N, Yamauchi T, Kadowaki T
- Journal Title
  
  J. Biol. Chem. 281
  
  Pages: 26602-26614
- Data Source
  KAKENHI-PROJECT-18659265
[Journal Article] Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome.2006
- Author(s)
  Kadowaki T, Yamauchi T, Kubota N, Hara K, Ueki K, Tobe K.
- Journal Title
  
  J Clin Invest. 116(7)
  
  Pages: 1784-1792
- Data Source
  KAKENHI-PROJECT-17390260
[Journal Article] Measurement of the high- molecular- weight form of adiponectin in plasma is useful for the prediction of insulin resistance and metabolic syndrome.2006
- Author(s)
  Hara T, Yamauchi T, Kadowaki T.
- Journal Title
  
  Diabetes Care 29
  
  Pages: 1357-1362
- Data Source
  KAKENHI-PROJECT-15081202
[Journal Article] Pioglitazone Ameliorates Insulin Resistance and Diabetes by Both Adiponectin-dependent and -independent Pathways2006
- Author(s)
  Kubota N, Terauchi Y, Kubota T, Kumagai H, Itoh S, Satoh H, Yano W, Ogata H, Tokuyama K, Takamoto I, Mineyama T, Ishikawa M, Moroi M, Sugi K, Yamauchi T, Ueki K, Tobe K, Noda T, Nagai R, Kadowaki T.
- Journal Title
  
  J. Biol. Chem. 281
  
  Pages: 8748-8755
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390270
[Journal Article] Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome.2006
- Author(s)
  Kadowaki T, Yamauchi T, Kubota N, Hara K, Ueki K, Tobe K.
- Journal Title
  
  J. Clin. Invest. 116
  
  Pages: 1784-1792
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209033
[Journal Article] Overexpression of MCP-1 in adipose tissues causes macrophage recruitment and insulin resistance2006
- Author(s)
  Kamei N, Tobe K, Suzuki R, Ohsugi M, Watanabe T, Kubota N, Ohtsuka-Kowatari N, Kumagai K, Sakamoto K, Kobayashi M, Yamauchi T, Ueki K, Oishi Y, Nishimura S, Manabe I, Hashimoto H, Ohnishi Y, Ogata H, Tokuyama K, Tsunoda M, Ide T, Murakami K, Nagai R, Kadowaki T.
- Journal Title
  
  J. Biol. Chem 281
  
  Pages: 26602-26614
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18209033
[Journal Article] Overexpression of MCP-1 in adipose tissues causes macrophage recruitment and insulin resistance.2006
- Author(s)
  Kamei N, Tobe K, Suzuki R, Ohsugi M, Watanabe T, Kubota N, Ohtsuka-Kowatari N, Kumagai K, Sakamoto K, Kobayashi M, Yamauchi T, Ueki K, Oishi Y, Nishimura S, Manabe I, Hashimoto H, Ohnishi Y, ogata H, Tokuyama K, Tsunoda M, Ide T, Murakami K, Tsunoda M, Id
- Journal Title
  
  J. Bio1. Chem. 281
  
  Pages: 26602-26614
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209033
[Journal Article] Measurement of the high-molecular-weight form of adiponectin in plasmais useful for the prediction of insulih resistance and metabolic syndrome.2006
- Author(s)
  Hara K, Horikoshi M, Yamauchi T, Yago H, Miyazaki O, Ebinuma H, Imai Y, Nagai R, Kadowaki T.
- Journal Title
  
  Diabetes Care 29
  
  Pages: 1357-1362
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390270
[Journal Article] Adiponectin-dependent and independent pathways in insulin-sensitizing and antidiabetic actions of thiazolidinediones.2006
- Author(s)
  Kubota N, Yamauchi T, Tobe K, Kadowaki, T
- Journal Title
  
  Diabetes 55 Suppl 2
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209033
[Journal Article] Measurement of the high- molecular- weight form of adiponectin in plasma is useful for the prediction of insulin resistance and metabolic syndrome.2006
- Author(s)
  Hara T, Yamauchi T, Kadowaki T
- Journal Title
  
  Diabetes Care 29
  
  Pages: 1357-1362
- Data Source
  KAKENHI-PROJECT-18659265
[Journal Article] Adiponectin-dependent and -independent pathways in insulin-sensitizing and antidiabetic actions of thiazolidinediones.2006
- Author(s)
  Kubota N, Yamauchi T, Kadowaki T.
- Journal Title
  
  Diabetes 55 Suppl 2
- Data Source
  KAKENHI-PROJECT-18209033
[Journal Article] Measurement of the high-molecular-weight form of adiponectin in plasma is useful for the prediction of insulin resistance and metabolic syndrome2006
- Author(s)
  Hara K, Horikoshi M, Yamauchi T, Yago H, Miyazaki O, Ebinuma H, Imai Y, Nagai R, Kadowaki T.
- Journal Title
  
  Diabetes Care 29
  
  Pages: 1357-1362
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18209033
[Journal Article] Adiponectin-dependent and -independent pathways in insulin-sensitizing and antidiabetic actions of thiazolidinediones.2006
- Author(s)
  Kubota N, Yamauchi T, Kadowaki T
- Journal Title
  
  Diabetes 55 Suppl 2
- Data Source
  KAKENHI-PROJECT-18659265
[Journal Article] Measurement of the high- molecular- weight form of adiponectin in plasma is useful for the prediction of insulin resistance and metabolic syndrome.2006
- Author(s)
  Hara T, Yamauchi T, Kadowaki T.
- Journal Title
  
  Diabetes Care 29
  
  Pages: 1357-1362
- Data Source
  KAKENHI-PROJECT-18209033
[Journal Article] Adiponectin-dependent and-independent pathways in insulin-sensitizing and antidiabetic actions of thiazolidinediones2006
- Author(s)
  Kubota N, Yamauchi T, Tobe K, Kadowaki, T.
- Journal Title
  
  Diabetes 55
  
  Pages: 32-38
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18209033
[Journal Article] Overexpression of MCP-1 in adipose tissues causes macrophage recruitment and insulin resistance.2006
- Author(s)
  ・Kubota N, Yamauchi T, Kadowaki T.
- Journal Title
  
  J. Biol. Chem. 281
  
  Pages: 26602-26614
- Data Source
  KAKENHI-PROJECT-18390270
[Journal Article] Overexpression of monocyte chemoattractant protein-1 in adipose tissues causes macrophage recruitment and insulin resistance.2006
- Author(s)
  Kamei N, Tobe K, Suzuki R, Ohsugi M, Watanabe T, Kubota N, Ohtsuka-Kowatari N, Kumagai K, Sakamoto K, Kobayashi M, Yamauchi T, Ueki K, Oishi Y, Nishimura S, Manabe I, Hashimoto H, Ohnishi Y, Ogata H, Tokuyama K, Tsunoda M, Ide T, Murakami K, Nagai R, Kadowaki T.
- Journal Title
  
  J Biol Chem. 281(36)
  
  Pages: 26602-26614
- Data Source
  KAKENHI-PROJECT-17390260
[Journal Article] Measurement of the high- molecular- weight form of adiponectin in plasma is useful for the prediction of insulin resistance and metabolic syndrome.2006
- Author(s)
  Hara T, Yamauchi T, Kadowaki T.
- Journal Title
  
  Diabetes Care 29
  
  Pages: 1357-1362
- Data Source
  KAKENHI-PROJECT-18390270
[Journal Article] Pioglitazone Ameliorates Insulin Resistance and Diabetes by Both Adiponectin-dependent and -independent Pathways.2006
- Author(s)
  Kubota N, Yamauchi T, Kadowaki T.
- Journal Title
  
  J. Biol. Chem. 281
  
  Pages: 8748-8755
- Data Source
  KAKENHI-PROJECT-18209033
[Journal Article] Overexpression of MCP-1 in adipose tissues causes macrophage recruitment and insulin resistance.2006
- Author(s)
  Kamei N, Tobe K, Suzuki R, Ohsugi M, Watanabe T, Kubota N, Ohtsuka-Kowatari N, Kumagai K, Sakamoto K, Kobayashi M, Yamauchi T, Ueki K, Oishi Y, Nishimura S, Manabe I, Hashimoto H, Ohnishi Y, Ogata H, Tokuyama K, Tsunoda M, Ide T, Murakami K, Nagai R, Kadowaki T.
- Journal Title
  
  J.Biol. Chem. 281
  
  Pages: 26602-26614
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390270
[Journal Article] Adiponectin-dependent and -independent pathways in insulin-sensitizing and antidiabetic actions of thiazolidinediones.2006
- Author(s)
  Kubota N, Yamauchi T, Kadowaki T.
- Journal Title
  
  Diabetes 55 Suppl 2
- Data Source
  KAKENHI-PROJECT-15081202
[Journal Article] Pioglitazone Ameliorates Insulin Resistance and Diabetes by Both Adiponectin-dependent and -independent Pathways.2006
- Author(s)
  Kubota N, Yamauchi T, Kadowaki T.
- Journal Title
  
  J. Biol. Chem. 281
  
  Pages: 8748-8755
- Data Source
  KAKENHI-PROJECT-18390270
[Journal Article] Pioglitazone Ameliorates Insulin Resistance and Diabetes by Both Adiponectin-dependent and-independent Pathways.2006
- Author(s)
  Kubota N, Terauchi Y, Kubota T, Kumagai H, Itoh S, Satoh H, Yano W, Ogata H, Tokuyama K, Takamoto I, Mineyama T, lshikawa M, Moroi M, Sugi K, Yamauchi T, Ueki K, Tobe K, Noda T, Nagai R, Kadowaki T.
- Journal Title
  
  J.Biol. Chem. 281
  
  Pages: 8748-8755
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390270
[Journal Article] Pioglitazone Ameliorates Insulin Resistance and Diabetes by Both Adiponectin-dependent and -independent Pathways.2006
- Author(s)
  Kubota N, Yamauchi T, Kadowaki T.
- Journal Title
  
  J. Biol. Chem. 281
  
  Pages: 8748-8755
- Data Source
  KAKENHI-PROJECT-15081202
[Journal Article] Pioglitazone Ameliorates Insulin Resistance and Diabetes by Both Adiponectin-dependent and -independent Pathways.2006
- Author(s)
  Kubota N, Yamauchi T, Kadowaki T
- Journal Title
  
  J. Biol. Chem. 281
  
  Pages: 8748-8755
- Data Source
  KAKENHI-PROJECT-18659265
[Journal Article] Overexpression of MCP-1 in adipose tissues causes macrophage recruitment and insulin resistance2006
- Author(s)
  Kamei N, Tobe K, Suzuki R, Ohsugi M, Watanabe T, Kubota N, Ohtsuka-Kowatari N, Kumagai K, Sakamoto K, Kobayashi M, Yamauchi T, Ueki K, Oishi Y, Nishimura S, Manabe I, Hashimoto H, Ohnishi Y, Ogata H, Tokuyama K, Tsunoda M, Ide T, Murakami K, Nagai R, Kadowaki T.
- Journal Title
  
  J. Biol. Chem. 281
  
  Pages: 26602-26614
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390270
[Journal Article] Adiponectin and adiponectin receptors in insulin resistance, diabetes,and the metabolic syndrome.2006
- Author(s)
  Kadowaki T, Yamauchi T, Kubota N, Hara K, Ueki K, Tobe K.
- Journal Title
  
  J.Clin. Invest. 116
  
  Pages: 1784-1792
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390270
[Journal Article] Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome2006
- Author(s)
  Kadowaki T, Yamauchi T, Kubota N, Hara K, Ueki K, Tobe K.
- Journal Title
  
  J. Clin. Invest 116
  
  Pages: 1784-1792
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18209033
[Journal Article] Pioglitazone Ameliorates Insulin Resistance and Diabetes by-Both Adiponectin-dependent and-independent Pathways2006
- Author(s)
  Kubota N, Terauchi Y, Kubota T, Kumagai H, Itoh S, Satoh H, Yano W, Ogata H, Tokuyama K, Takamoto I, Mineyama T, Ishikawa M, Moroi M, Sugi K, Yamauchi T, Ueki K, Tobe K, Noda T, Nagai R, Kadowaki T.
- Journal Title
  
  J. Biol. Chem 281
  
  Pages: 8748-8755
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18209033
[Journal Article] Adiponectin-dependent and-independent pathways in insulin-sensitizing and antidiabetic actions of thiazolidinediones.2006
- Author(s)
  Kubota N, Yamauchi T, Tobe K, Kadowaki, T
- Journal Title
  
  Diabetes 55 Suppl2
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390270
[Journal Article] Measurement of the high- molecular- weight form of adiponectin in plasma is useful for the prediction of insulin resistance and metabolic syndrome2006
- Author(s)
  Hara K, Horikoshi M, Yamauchi T, Yago H, Miyazaki O, Ebinuma H, Imai Y, Nagai R, Kadowaki T.
- Journal Title
  
  Diabetes Care 29
  
  Pages: 1357-1362
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390270
[Journal Article] Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome2006
- Author(s)
  Kadowaki T, Yamauchi T, Kubota N, Hara K, Ueki K, Tobe K.
- Journal Title
  
  J. Clin. Invest. 116
  
  Pages: 1784-1792
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390270
[Journal Article] Adiponectin-dependent and -independent pathways in insulin-sensitizing and antidiabetic actions of thiazolidinediones.2006
- Author(s)
  Kubota N, Yamauchi T, ・Kadowaki T.
- Journal Title
  
  Diabetes 55 Suppl 2
- Data Source
  KAKENHI-PROJECT-18390270
[Journal Article] Role of Kruppel-like factor 15 (KLF15) in transcriptional regulation of adipogenesis.2005
- Author(s)
  Mori T, Sakaue H, Iguchi H, Gomi H, Okada Y, Takashima Y, Nakamura K, Nakamura T, Yamauchi T, Kubota N, Kadowaki T, Matsuki Y, Ogawa W, Hiramatsu R, Kasuga M.
- Journal Title
  
  J. Biol. Chem. 280
  
  Pages: 12867-12875
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14013008
[Journal Article] Adiponectin and adiponectin receptors.2005
- Author(s)
  Kadowaki T, Yamauchi T.
- Journal Title
  
  26
  
  Pages: 439-51
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14013008
[Journal Article] Expression of DGAT2 in white adipose tissue is regulated by central leptin action.2005
- Author(s)
  Suzuki R, Tobe K, Aoyama M, Sakamoto K, Ohsugi M, Kamei N, Nemoto S, Inoue A, Ito Y, Uchida S, Hara K, Yamauchi T, Kubota N, Terauchi Y, Kadowaki T.
- Journal Title
  
  J. Biol. Chem. 280
  
  Pages: 3331-7
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14013008
[Journal Article] Osmotin is a homolog of mammalian adiponectin and controls apoptosis in yeastthrough a homolog of mammalian adiponectin receptor.2005
- Author(s)
  Narasimhan ML, Coca MA, Jin J, Yamauchi T, Ito Y, Kadowaki T, Kim KK, Pardo JM, Damsz B, Hasegawa PM, Yun DJ, Bressan RA.
- Journal Title
  
  Molecular Cell 17
  
  Pages: 171-80
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14013008
[Journal Article] Absence of an association between the polymorphisms in the genes encoding adiponectin receptors and type 2 diabetes.2005
- Author(s)
  Hara K, Horikoshi M, Kitazato H, Yamauchi T, Ito C, Noda M, Ohashi J, Froguel P, Tokunaga K, Nagai R, Kadowaki T.
- Journal Title
  
  Diabetologia 48
  
  Pages: 1307-14
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14013008
[Journal Article] Kruppel-like transcription factor KLF5 is a key_regulator of adipocyte differentiation.2005
- Author(s)
  Oishi Y, Manabe I, Tobe K, Tsushima K, Shindo T, Fujiu K, MD; Nishimura, Maemura K, Yamauchi T, Kubota N, Suzuki R, Kitamura T, Akira S, Kadowaki T, Nagai R.
- Journal Title
  
  Cell Metabolism 1
  
  Pages: 27-39
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14013008
[Journal Article] Nuclear receptors as targets for drug development : molecular mechanisms for regulation of obesity and insulin resistance by peroxisome proliferator-activated receptor gamma, CREB-binding protein, and adiponectin.2005
- Author(s)
  Tsuchida A, Yamauchi T, Kadowaki T.
- Journal Title
  
  J. Pharmacol. Sci. 97
  
  Pages: 164-70
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14013008
[Journal Article] Angiopoietin-related growth factor antagonizes obesity and insulin resistance.2005
- Author(s)
  Oike Y, Akao M, Yasunaga K, Yamauchi T, Morisada T, Ito Y, Urano T, Kimura Y, Kubota Y, Maekawa H, Miyamoto T, Miyata K, Matsumoto SI, Sakai J, Nakagata N, Takeya M, Koseki H, Ogawa Y, Kadowaki T, Suda T.
- Journal Title
  
  Nature Medicine 11
  
  Pages: 400-8
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14013008
[Journal Article] Increased serum leptin protects from adiposity despite the increased glucose upt ake in white adipose tissue in mice lacking p85alpha PI 3-kinase.2004
- Author(s)
  Terauchi Y, Matsui J, Kamon J, Yamauchi T, Kubota N, Komeda K, Aizawa S, Akanuma Y, Tomita M, Kadowaki T
- Journal Title
  
  Diabetes 53
  
  Pages: 2261-2270
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14013008
[Journal Article] Insulin/Foxol pathway regulates expression levels of adiponectin receptors and adiponectin sensitivity.2004
- Author(s)
  Tsuchida A, Yamauchi T, Ito Y, Hada Y, Maki T, Takekawa S, Kamon J, Kobayashi M, Suzuki R, Ham K, Kubota N, Terauchi Y, Froguel P, Nakae J, Kasuga M, Accili D, Tobe K, Ueki K, Nagai R, Kadowaki T.
- Journal Title
  
  J. Biol. Chem. 279
  
  Pages: 30817-30822
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14013008
[Journal Article] A novel IKK beta inhibitor stimulates adiponectin levels and ameliorates obesity-linked insulin resistance.2004
- Author(s)
  Kamon J, Yamauchi T, Muto S, Takekawa S, Ito Y, Hada Y, Ogawa W, Itai A, Kasuga M, Tobe K, Kadowaki T.
- Journal Title
  
  Biochem. Biophys. Res. Commun. 323
  
  Pages: 242-8
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14013008
[Journal Article] Pioglitazone reduces islet triglyceride content and restores impaired glucose-stimulated insulin secretion in heterozygous PPARγ-deficient mice on a high-fat diet.2004
- Author(s)
  Matsui J, Terauchi Y, Kubota N, Takamoto I, Eto K, Yamashita T, Komeda K, Yamauchi T, Kamon J, Kita S, Noda M, Kadowaki T.
- Journal Title
  
  Diabetes 53
  
  Pages: 2844-2854
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14013008
[Journal Article] Generation of globular fragment of adiponectin by leukocyte elastase secreted by monocytic cell line THP-1.2004
- Author(s)
  Waki H.Yamauchi T.Kamon J.Kita S.Ito Y.Hada Y.UchidaS.Tsuchida A.Takekawa S., Kadowaki T.
- Journal Title
  
  Endocrinology 146
  
  Pages: 790-6
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14013008
[Journal Article] Both insulin signaling defects in the liver and obesity contribute to insulin resistance and cause diabetes in IRS2-/- mice.2004
- Author(s)
  Suzuki R, Tobe K, Aoyama M, Yamauchi T, Kamon J, Kubota N, Terauchi Y, Yoshimitsu H, Matsuhisa M, Nagasaka S, Ogata H, Tokuyama K, Nagai R, Kadowaki T.
- Journal Title
  
  J. Biol. Chem. 279
  
  Pages: 25039-25049
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14013008
[Journal Article] Role of UCP-2 up-regulation and TG accumulation in impaired glucose-stimulated insulin secretion in a β-Cell lipotoxicity model overexpressing SREBP-1c.2004
- Author(s)
  Yamashita T, Eto K, Okazaki Y, Yamashita S, Yamauchi T, Sekine N, Nagai R, Noda M, Kadowaki T.
- Journal Title
  
  Endocrinology 145
  
  Pages: 3566-3577
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14013008
[Journal Article] Cloning of adiponectin receptors that mediate antidiabetic metabolic effects.2003
- Author(s)
  Yamauchi, T., et al.
- Journal Title
  
  Nature 423
  
  Pages: 762-769
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390284
[Journal Article] Cloning of adiponectin receptors that mediate antidiabetic metabolic effects.2003
- Author(s)
  Yamauchi T, Kamon J, Ito Y, Tsuchida A, Yokomizo T, Kita S, Sugiyama T, Miyagishi M, Ham K, Tsunoda M, Murakami K, Ohteki T, Uchida S, Takekawa S, Waki H, Tsuno NH, Shibata Y, Terauchi Y, Froguel P, Tobe K, Koyasu S, Taira K, Kitamura T, Shimizu T, Nagai R, Kadowaki T.
- Journal Title
  
  Nature 423
  
  Pages: 762-769
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14013008
[Journal Article] Molecular mechanism of insulin resistance and obesity.2003
- Author(s)
  Kadowaki T, Hara K, Yamauchi T, Terauchi Y, Tobe K, Nagai R.
- Journal Title
  
  Exp. Biol. Med. 228
  
  Pages: 1111-1117
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14013008
[Journal Article] Dual roles of adiponectin/Acrp30 in vivo as an anti-diabetic and anti-atherogenic adipokine.2003
- Author(s)
  Yamauchi T
- Journal Title
  
  Curr Drug Targets Immune Endocr Metabol Disord 3
  
  Pages: 243-254
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14013008
[Journal Article] Cloning of adiponectin receptors that mediate antidiabetic metabolic effects.2003
- Author(s)
  Yamauchi, T, et al.
- Journal Title
  
  Nature 423
  
  Pages: 762-769
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390284
[Journal Article] Cloning of adiponectin receptors that mediate antidiabetic metabolic effects2003
- Author(s)
  Yamauchi T
- Journal Title
  
  Nature 423
  
  Pages: 762-769
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14013008
[Journal Article] Globular adiponectin protected ob/ob mice from diabetes and apoE deficient mice from atherosclerosis.2003
- Author(s)
  Yamauchi T, Kamon J, Waki H, Imai Y, Shimozawa N, Hioki K, Uchida S, Ito Y, Matsui J, Eto K, Komeda K, Tsunoda M, Murakami K, Ohnishi Y, Yamamura K, Ueyama Y, Froguel P, Kimura S, Nagai R, Kadowaki T.
- Journal Title
  
  J. Riot Chem. 278
  
  Pages: 2461-2468
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14013008
[Journal Article] Impaired multimerization of human adiponectin mutants associated with diabetes. Molecular structure and multimer formation of adiponectin.2003
- Author(s)
  Waki H, Yamauchi T, Kamon J, Ito Y, Uchida S, Kita S, Hara K, Hada Y, Vasseur F, Froguel P, Kimura S, Nagai R, Kadowaki T.
- Journal Title
  
  J. Biol. Chem. 278
  
  Pages: 40352-40363
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14013008
[Journal Article] Globular adiponectin protected ob/ob mice from diabetes and apoE deficient mice from atherosclerosis2003
- Author(s)
  Yamauchi T
- Journal Title
  
  J. Biol. Chem. 278
  
  Pages: 2461-2468
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14013008
[Journal Article] Dual roles of adiponectin/Acrp30 in vivo as an anti-diabetic and anti-atherogenic adipokine.2003
- Author(s)
  Yamauchi T, Hara K, Kubota N, Terauchi Y, Tobe K, Froguel P, Nagai R, Kadowaki T.
- Journal Title
  
  Curr Drug Targets Immune Endocr Metabol Disord 3
  
  Pages: 243-254
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14013008
[Journal Article] Disruption of adiponectin causes insulin resistance and neointimal formation.2002
- Author(s)
  Kubota N, Terauchi Y, Yamauchi T, Kubota T, Moroi M, Matsui J, Eto K, Yamashita T, Kamon J, Satoh H, Yano W, Froguel P, Nagai R, Kimura S, Kadowaki T, Noda T.
- Journal Title
  
  J. Biol. Chem 277
  
  Pages: 25863-25866
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14013008
[Journal Article] Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase.2002
- Author(s)
  Yamauchi T
- Journal Title
  
  Nature Medicine 8
  
  Pages: 1288-1295
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14013008
[Journal Article] Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase.2002
- Author(s)
  Yamauchi T, Kamon J, Minokoshi Y, Ito Y, Waki H, Uchida S, Yamashita S, Noda M, Kita S, Ueki K, Eto K, Akanuma Y, Froguel P, Foufelle F, Ferre P, Carling D, Kimura S, Nagai R, Kahn BB, Kadowaki T.
- Journal Title
  
  Nature Medicine 8
  
  Pages: 1288-1295
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14013008
[Journal Article] Maturity-onset diabetes of the young resulting from a novel mutation in the HNF-4alpha gene.2002
- Author(s)
  Hara K, Noda M, Waki H, Tobe K, Yamauchi T, Kadowaki H, Satou H, Tsukamoto K, Nagamatsu S, Yamagata K, Matsuzawa Y, Akanuma Y, Kimura S, Kadowaki T.
- Journal Title
  
  Intern Med 41
  
  Pages: 848-852
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14013008
[Journal Article] The role of PPAR gamma in high-fat diet-induced obesity and insulin resistance.2002
- Author(s)
  Kadowaki T, Hara K, Kubota N, Tobe K, Terauchi Y, Yamauchi T, Eto K, Kadowaki H, Noda M, Hagura R, Akanuma Y.
- Journal Title
  
  J Diabetes Complications 16
  
  Pages: 41-45
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14013008
[Journal Article] Genetic variation in the gene encoding adiponectin is associated with an increased risk of type 2 diabetes in the Japanese population.2002
- Author(s)
  Hara K, Boutin P, Mori Y, Tobe K, Dina C, Yasuda K, Yamauchi T, Otabe S, Okada T, Eto K, Kadowaki H, Hagura R, Akanuma Y, Yazaki Y, Nagai R, Taniyama M, Matsubara K, Yoda M, Nakano Y, Tomita M, Kimura S, Ito C, Froguel P, Kadowaki T.
- Journal Title
  
  Diabetes 51
  
  Pages: 536-540
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14013008
[Journal Article] Increased insulin sensitivity despite lipodystrophy in Crebbp heterozygous mice.2002
- Author(s)
  Yamauchi T, Oike Y, Kamon J, Waki H, Komeda K, Tsuchida A, Date Y, Li MX, Miki H, Akanuma Y, Nagai R, Kimura S, Saheki T, Nakazato M, Naitoh T, Yamamura K, Kadowaki T.
- Journal Title
  
  Nature Genetics 30
  
  Pages: 221-226
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14013008
[Journal Article] Increased insulin sensitivity despite lipodystrophy in Crebbp heterozygous mice2002
- Author(s)
  Yamauchi T
- Journal Title
  
  Nature Genetics 30
  
  Pages: 221-226
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14013008
[Journal Article] The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity.2001
- Author(s)
  Yamauchi T, Kamon J, Waki H, Terauchi Y, Kubota N, Hara K, Mori Y, Ide T, Murakami K, Tsuboyama-Kasaoka N, Ezaki O, AkanumaY, Gavrilova O, Vinson C, Reitman ML, Kagechika H, Shudo K, Yoda M, Nakano Y, Tobe K, Nagai R, Kimura S, Tomita M, Froguel P, Kadowaki T.
- Journal Title
  
  Nature Medicine 7
  
  Pages: 941-946
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14013008
[Journal Article] The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity2001
- Author(s)
  Yamauchi T
- Journal Title
  
  Nature Medicine 7
  
  Pages: 941-946
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14013008
[Patent] Activator of adiponectin receptor2020
- Inventor(s)
  門脇孝、山内敏正、岩部美紀、岩部真人、横山茂之, 他
- Industrial Property Rights Holder
  国立大学法人東京大学/理化学研究所
- Industrial Property Rights Type
  特許
- Acquisition Date
  2020
- Overseas
- Data Source
  KAKENHI-PROJECT-26000012
[Patent] アディポネクチン受容体活性化化合物2020
- Inventor(s)
  門脇孝、山内敏正、岩部美紀、岩部真人、横山茂之, 他
- Industrial Property Rights Holder
  国立大学法人東京大学/理化学研究所
- Industrial Property Rights Type
  特許
- Acquisition Date
  2020
- Data Source
  KAKENHI-PROJECT-26000012
[Patent] Activator of adiponectin receptor2017
- Inventor(s)
  門脇孝、山内敏正、岩部美紀、岩部真人、横山茂之、本間光貴
- Industrial Property Rights Holder
  国立大学法人東京大学/理化学研究所
- Industrial Property Rights Type
  特許
- Filing Date
  2017
- Overseas
- Data Source
  KAKENHI-PROJECT-26000012
[Patent] アディポネクチン受容体活性化化合物2014
- Inventor(s)
  門脇孝, 山内敏正, 岩部真人, 岩部美紀, 横山茂之
- Industrial Property Rights Holder
  国立大学法人東京大学
- Industrial Property Rights Type
  特許
- Filing Date
  2014-09-30
- Data Source
  KAKENHI-PROJECT-26000012
[Patent] 擬似運動療法のための医薬2011
- Inventor(s)
  門脇孝、山内敏正、他2名
- Industrial Property Rights Holder
  (株)東京大学TLO
- Filing Date
  2011-03-15
- Overseas
- Data Source
  KAKENHI-PROJECT-20229008
[Patent] アディポネクチン受容体及びそれをコードする遺伝子2010
- Inventor(s)
  門脇孝、山内敏正、他2名
- Industrial Property Rights Holder
  東京大学TLO、日産化学工業(株)
- Acquisition Date
  2010-01-22
- Data Source
  KAKENHI-PROJECT-20229008
[Patent] A homolog of human adiponectin receptor controls osmotin-induced apoptosis in yeast2004
- Inventor(s)
  Narasimhan ML, Yun DJ, Bressan RA, 山内敏正, 門脇孝
- Industrial Property Rights Holder
  Narasimhan ML, Yun DJ, Bressan RA, 山内敏正, 門脇孝
- Filing Date
  2004-09-30
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14013008
[Patent] A Homolog of Adiponectin Receptor controls Osmotin-Induced Apoptosis in Yeast2004
- Inventor(s)
  山内敏正ら
- Industrial Property Rights Holder
  山内敏正ら
- Filing Date
  2004-09-28
- Data Source
  KAKENHI-PROJECT-15081202
[Patent] アディポネクチンの新規用途2003
- Inventor(s)
  門脇孝, 山内敏正, 高田誠, 他1名
- Industrial Property Rights Holder
  門脇孝, 住友製薬(株)
- Filing Date
  2003-05-20
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14013008
[Presentation] NFIAはマウス白色脂肪組織の褐色脂肪遺伝子群を制御し高脂肪食下の肥満抵抗性に寄与する2021
- Author(s)
  斎藤楓、脇裕典、平池勇雄、和田孝人、大口弥里、川口智也、青山倫久、窪田哲也、窪田直人、門脇孝、山内敏正
- Organizer
  第41回日本肥満学会／第38回日本肥満症治療学会学術集会
- Data Source
  KAKENHI-PROJECT-20H04101
[Presentation] インスリン抵抗性の分子機序2021
- Author(s)
  山内　敏正
- Organizer
  第55回糖尿病学の進歩
- Invited
- Data Source
  KAKENHI-PROJECT-18H04053
[Presentation] 内臓脂肪蓄積と白色・褐色脂肪細胞の活性制御褐色脂肪細胞のエピゲノム制御と肥満症における意義2021
- Author(s)
  脇裕典、大口弥里、斎藤楓、平池勇雄、山内敏正
- Organizer
  第41回日本肥満学会／第38回日本肥満症治療学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-20H04101
[Presentation] 糖尿病と内臓脂肪2021
- Author(s)
  山内　敏正
- Organizer
  第41回日本肥満学会・第38回日本肥満症治療学会
- Invited
- Data Source
  KAKENHI-PROJECT-18H04053
[Presentation] NFIAの全身代謝における生理的役割の検討2021
- Author(s)
  大口弥里、脇裕典、平池勇雄、和田孝人、斎藤楓、青山倫久、窪田哲也、窪田直人、門脇孝、山内敏正
- Organizer
  第41回日本肥満学会／第38回日本肥満症治療学会学術集会
- Data Source
  KAKENHI-PROJECT-20H04101
[Presentation] 糖尿病・代謝疾患の克服と健康長寿実現に向けて2020
- Author(s)
  山内　敏正
- Organizer
  日本糖尿病学会中国四国地方会第58回総会
- Invited
- Data Source
  KAKENHI-PROJECT-18H04053
[Presentation] アディポネクチン受容体AdipoRの病態生理的意義の解明2020
- Author(s)
  山内　敏正
- Organizer
  第52回日本動脈硬化学会総会・学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18H04053
[Presentation] 超・超高齢社会における糖尿病・代謝疾患の克服と健康長寿の実現に向けた体質医学研究2020
- Author(s)
  山内　敏正
- Organizer
  第70回日本体質医学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-18H04053
[Presentation] インスリン抵抗性の分子機序と治療戦略―アディポネクチンを中心に―2020
- Author(s)
  山内　敏正
- Organizer
  第94回日本糖尿病学会中部地方会
- Invited
- Data Source
  KAKENHI-PROJECT-18H04053
[Presentation] Transcriptional Regulation of Brown-Fat-Specific Genes by Nuclear Factor I-A and Its Role in Energy Homeostasis2020
- Author(s)
  脇裕典、平池勇雄、大口弥里、斎藤楓、和田孝人、堤修一、油谷浩幸、山内敏正、門脇孝
- Organizer
  第63回日本糖尿病学会年次学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-20H04101
[Presentation] NFIAが制御する新規標的遺伝子群の同定と褐色脂肪細胞におけるその機能的意義の検討2020
- Author(s)
  大口弥里、脇裕典、平池勇雄、和田孝人、斎藤楓、三好建吾、山内敏正、門脇孝
- Organizer
  第63回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-20H04101
[Presentation] 脂肪組織におけるNFIAは食事誘導性肥満に保護的に作用する2020
- Author(s)
  斎藤楓、脇裕典、平池勇雄、和田孝人、大口弥里、川口智也、三好建吾、田丸新一、門脇孝、山内敏正
- Organizer
  第63回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-20H04101
[Presentation] Predictive ：ゲノム、エピゲノム情報による糖尿病発症・重症化の予測2019
- Author(s)
  山内　敏正
- Organizer
  第62回日本糖尿病学会年次学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18H04053
[Presentation] Obesity treatments Lifestyle modifications2019
- Author(s)
  Toshimasa Yamauchi　（山内　敏正）
- Organizer
  International Diabetes Federation Congress2019
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H04053
[Presentation] 新規マイオカインの同定と糖・脂質・エネルギー代謝に対する作用の検討2019
- Author(s)
  小田原紗羅、岩部美紀、岩部真人、山内敏正
- Organizer
  第62回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-18H04053
[Presentation] 「内分泌代謝とエピゲノム「糖尿病や肥満症の病態形成に影響を及ぼすメタボリックメモリー理解に向けたエピゲノム解析」2019
- Author(s)
  山内　敏正
- Organizer
  第92回日本内分泌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-18H04053
[Presentation] 糖尿病・代謝疾患の克服と健康長寿の実現に向けて2019
- Author(s)
  山内　敏正
- Organizer
  第37回内分泌代謝学サマーセミナー
- Invited
- Data Source
  KAKENHI-PROJECT-18H04053
[Presentation] 糖尿病・代謝疾患の克服と健康長寿実現に向けて2019
- Author(s)
  山内　敏正
- Organizer
  Young! Diabetologists Research Forum
- Data Source
  KAKENHI-PROJECT-18H04053
[Presentation] インスリン受容体およびIGF-1受容体のtyrosine kinase domainにおける変異と臨床的重症度の関連の解明2018
- Author(s)
  細江隼, 門脇弘子, 高倉美菜香, 宮冬樹, 角田達彦, 鈴木顕, 庄嶋伸浩, 山内
- Organizer
  第61回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-18H04053
[Presentation] Genotype-phenotype Correlations and Structural Basis of the Pathogenic 　　　　　　　 Mutations in INSR and IGF1R2018
- Author(s)
  Jun Hosoe, Hiroko Kadowaki, Fuyuki Miya, Minaka Takakura, Ken Suzuki, Tatsuhiko Tsunoda, Nobuhiro Shojima, Toshimasa Yamauchi, Takashi Kadowaki.
- Organizer
  the 78th Scientific Sessions of the American Diabetes　Association
- Data Source
  KAKENHI-PROJECT-18H04053
[Presentation] アディポネクチン受容体の構造と機能2018
- Author(s)
  岩部（岡田）美紀、山内　敏正、岩部　真人、門脇　孝
- Organizer
  第12回　炎症・脂質代謝・メタボリサーチフォーラム
- Invited
- Data Source
  KAKENHI-PROJECT-16K15487
[Presentation] 大学発の新規生活習慣病治療薬開発におけるトランスレーショナルリサーチの実現に向けて2018
- Author(s)
  岩部　美紀、山内　敏正、岩部　真人、門脇　孝
- Organizer
  東大病院先端医療シーズ開発フォーラム2018
- Data Source
  KAKENHI-PROJECT-16K15487
[Presentation] Genotype-structure-phenotype Correlations in extreme insulin 　　　　　　　 resistance evaluate d by structural bioinformatics analysis of the insulin receptor2018
- Author(s)
  Jun Hosoe, Minaka Takakura, Nobuhiro Shojima, Toshimasa Yamauchi, Takashi Kadowa ki
- Organizer
  第18回東京大学生命科学シンポジウム
- Data Source
  KAKENHI-PROJECT-18H04053
[Presentation] Structural basis of mutations of the tyrosine kinase domain in INSR and the relations with clinical severity.2018
- Author(s)
  細江隼、門脇弘子、宮冬樹、高倉美菜香、鈴木顕、田中真生、石浦浩之、辻省次、原一雄、角田達彦、庄嶋伸浩、山内敏正、門脇孝
- Organizer
  第63回日本人類遺伝学会
- Data Source
  KAKENHI-PROJECT-18H04053
[Presentation] Novel structures and functions of adiponectin receptors2017
- Author(s)
  岩部（岡田）美紀、山内　敏正、岩部　真人、門脇　孝
- Organizer
  DISIRE Conference 2017
- Invited
- Data Source
  KAKENHI-PROJECT-16K15487
[Presentation] アディポネクチン受容体の立体構造情報を利用したアゴニストの最適化に向けた検討2017
- Author(s)
  岩部　美紀、山内　敏正、岩部　真人、門脇　孝
- Organizer
  第60回　日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-16K15487
[Presentation] 「アディポネクチン受容体の抗体創薬に向けた検討と解析」2017
- Author(s)
  岩部　美紀、山内　敏正、岩部　真人、門脇　孝
- Organizer
  第10回　システム疾患生命科学による先端医療技術開発シンポジウム
- Place of Presentation
  東京大学武田先端知ビル（東京都文京区）
- Year and Date
  2017-03-11
- Data Source
  KAKENHI-PROJECT-16K15487
[Presentation] 「アディポネクチン受容体の抗体創薬に向けた検討と解析」2017
- Author(s)
  岩部　美紀、山内　敏正、岩部　真人、門脇　孝
- Organizer
  第10回　システム疾患生命科学による先端医療技術開発シンポジウム
- Place of Presentation
  東京大学武田先端知ビル（東京都文京区）
- Year and Date
  2017-03-11
- Data Source
  KAKENHI-PROJECT-26293216
[Presentation] 「大学発の新規糖尿病治療薬開発におけるトランスレーショナルリサーチの実現を目指して」2017
- Author(s)
  岩部　美紀、山内　敏正、岩部　真人、門脇　孝
- Organizer
  東大病院先端医療シーズ開発フォーラム2017
- Place of Presentation
  東京大学伊藤国際学術研究センター（東京都文京区）
- Year and Date
  2017-02-02
- Data Source
  KAKENHI-PROJECT-26293216
[Presentation] アディポネクチン・アディポネクチン受容体研究の最前線2017
- Author(s)
  岩部　美紀、山内　敏正、岩部　真人、門脇　孝
- Organizer
  第38回　日本肥満学会
- Invited
- Data Source
  KAKENHI-PROJECT-16K15487
[Presentation] 「大学発の新規糖尿病治療薬開発におけるトランスレーショナルリサーチの実現を目指して」2017
- Author(s)
  岩部　美紀、山内　敏正、岩部　真人、門脇　孝
- Organizer
  東大病院先端医療シーズ開発フォーラム2017
- Place of Presentation
  東京大学伊藤国際学術研究センター（東京都文京区）
- Year and Date
  2017-02-02
- Data Source
  KAKENHI-PROJECT-16K15487
[Presentation] アディポネクチン受容体アゴニストの糖尿病治療への応用に向けた検討と解析2017
- Author(s)
  岩部　美紀、山内　敏正、岩部　真人、門脇　孝
- Organizer
  第90回　日本内分泌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K15487
[Presentation] 「アディポネクチン受容体の立体構造とアゴニストの最適化に向けた検討と解析」2016
- Author(s)
  岩部　美紀、山内　敏正、岩部　真人、門脇　孝
- Organizer
  第89回　日本内分泌学会学術総会
- Place of Presentation
  国立京都国際会館（京都府京都市）
- Year and Date
  2016-04-21
- Data Source
  KAKENHI-PROJECT-16K15487
[Presentation] 「アディポネクチン受容体アゴニストの肥満症治療への応用に向けた挑戦」2016
- Author(s)
  岩部　美紀、山内　敏正、岩部　真人、門脇　孝
- Organizer
  第37回　日本肥満学会
- Place of Presentation
  東京ファッションタウンビル（東京都江東区）
- Year and Date
  2016-10-07
- Data Source
  KAKENHI-PROJECT-26293216
[Presentation] 「アディポネクチン受容体の構造と機能解明」2016
- Author(s)
  岩部　美紀、山内　敏正、岩部　真人、門脇　孝
- Organizer
  第21回　アディポサイエンスシンポジウム
- Place of Presentation
  千里ライフサイエンスセンター（大阪府豊中市）
- Year and Date
  2016-08-20
- Data Source
  KAKENHI-PROJECT-16K15487
[Presentation] アディポネクチン・AdipoRの肥満症における病態生理的意義2016
- Author(s)
  山内敏正、岩部美紀岩部真人　門脇　孝
- Organizer
  第89回日本内分泌学会学術総会
- Place of Presentation
  京都国際会館（京都市）
- Year and Date
  2016-04-20
- Data Source
  KAKENHI-PROJECT-26253058
[Presentation] 「アディポネクチン受容体の立体構造とアゴニストの最適化に向けた検討と解析」2016
- Author(s)
  岩部　美紀、山内　敏正、岩部　真人、門脇　孝
- Organizer
  第59回　日本糖尿病学会年次学術集会
- Place of Presentation
  国立京都国際会館（京都府京都市）
- Year and Date
  2016-05-21
- Data Source
  KAKENHI-PROJECT-16K15487
[Presentation] アディポネクチン受容体の抗体創薬に向けた検討と解析2016
- Author(s)
  岩部　美紀、山内　敏正、岩部　真人、門脇　孝
- Organizer
  第9回システム疾患生命科学による先端医療技術開発シンポジウム
- Place of Presentation
  東京大学山上会館（東京都文京区）
- Year and Date
  2016-02-12
- Data Source
  KAKENHI-PROJECT-26293216
[Presentation] ２型糖尿病の分子メカニズムと治療戦略2016
- Author(s)
  山内敏正
- Organizer
  第53回日本臨床分子医学会学術集会
- Place of Presentation
  東京国際フォーラム
- Invited
- Data Source
  KAKENHI-PROJECT-26253058
[Presentation] 「アディポネクチン受容体の立体構造とアゴニストの最適化に向けた検討と解析」2016
- Author(s)
  岩部　美紀、山内　敏正、岩部　真人、門脇　孝
- Organizer
  第89回　日本内分泌学会学術総会
- Place of Presentation
  国立京都国際会館（京都府京都市）
- Year and Date
  2016-04-21
- Data Source
  KAKENHI-PROJECT-26293216
[Presentation] 「アディポネクチン受容体アゴニストの肥満症治療への応用に向けた挑戦」2016
- Author(s)
  岩部　美紀、山内　敏正、岩部　真人、門脇　孝
- Organizer
  第37回　日本肥満学会
- Place of Presentation
  東京ファッションタウンビル（東京都江東区）
- Year and Date
  2016-10-07
- Data Source
  KAKENHI-PROJECT-16K15487
[Presentation] 「アディポネクチン受容体の構造と機能解明」2016
- Author(s)
  岩部　美紀、山内　敏正、岩部　真人、門脇　孝
- Organizer
  第21回　アディポサイエンスシンポジウム
- Place of Presentation
  千里ライフサイエンスセンター（大阪府豊中市）
- Year and Date
  2016-08-20
- Data Source
  KAKENHI-PROJECT-26293216
[Presentation] 「アディポネクチン受容体の立体構造とアゴニストの最適化に向けた検討と解析」2016
- Author(s)
  岩部　美紀、山内　敏正、岩部　真人、門脇　孝
- Organizer
  第59回　日本糖尿病学会年次学術集会
- Place of Presentation
  国立京都国際会館（京都府京都市）
- Year and Date
  2016-05-21
- Data Source
  KAKENHI-PROJECT-26293216
[Presentation] ２型糖尿病と組織幹細胞老化の連関メカニズムの解明2016
- Author(s)
  田丸新一、山内敏正、杉山拓也、岩部美紀、岩部真人、門脇孝
- Organizer
  第５９回　日本糖尿病学会学術集会
- Place of Presentation
  京都国際会館（京都市）
- Year and Date
  2016-05-18
- Data Source
  KAKENHI-PUBLICLY-15H01507
[Presentation] Crystal structures of the human adiponectin receptors2015
- Author(s)
  MIKI OKADA-IWABU, TOSHIMASA YAMAUCHI, MASATO IWABU,TAKASHI KADOWAKI
- Organizer
  2016 Keystone Symposia Conference T2: Diabetes: New Insights into Molecular Mechanisms and Therapeutic Strategies
- Place of Presentation
  Westin Miyako Kyoto（京都府京都市）
- Year and Date
  2015-10-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293216
[Presentation] アディポネクチンを標的とした糖尿病・糖尿病合併症の治療2015
- Author(s)
  岩部　美紀、山内　敏正、岩部　真人、門脇　孝
- Organizer
  第88回　日本内分泌学会学術総会
- Place of Presentation
  ホテルニューオータニ（東京都千代田区）
- Year and Date
  2015-04-25
- Invited
- Data Source
  KAKENHI-PROJECT-26293216
[Presentation] アディポネクチン受容体の病態生理学的意義2015
- Author(s)
  山内　敏正
- Organizer
  第88回日本内分泌学会学術総会
- Place of Presentation
  ホテルニューオータニ (東京都千代田区)
- Year and Date
  2015-04-23
- Invited
- Data Source
  KAKENHI-PUBLICLY-15H01507
[Presentation] ２型糖尿病疾患疾患感受性遺伝子とアンチエイジング2015
- Author(s)
  山内　敏正
- Organizer
  第15回日本抗加齢医学会総会
- Place of Presentation
  福岡国際会議場 (福岡県福岡市)
- Year and Date
  2015-05-30
- Invited
- Data Source
  KAKENHI-PUBLICLY-15H01507
[Presentation] Mutational Analyses Based on Crystal Structures of AdipoRs Facilitate understanding of NobelStructure-Function Relationships Including Adiponectin Binding and intrasellular Signal Transduction.2015
- Author(s)
  Toshimasa Yamauchi, Miki Okada-Iwabu, Masato Iwabu, Takashi Kadowaki
- Organizer
  American Diabetes Association 75th Scientific Sessions
- Place of Presentation
  ボストン(アメリカ)
- Year and Date
  2015-06-08
- Data Source
  KAKENHI-PUBLICLY-15H01507
[Presentation] ２型糖尿病疾患疾患感受性遺伝子とアンチエイジング2015
- Author(s)
  山内　敏正
- Organizer
  第15回日本抗加齢医学会総会
- Place of Presentation
  福岡国際会議場 (福岡県福岡市)
- Year and Date
  2015-05-30
- Invited
- Data Source
  KAKENHI-PROJECT-26253058
[Presentation] Pathophysiological roles of adipokine and epigenome dysregulation in obesity.2015
- Author(s)
  Toshimasa Yamauchi
- Organizer
  The 46th NIPS international Symposium
- Place of Presentation
  名古屋国際会議場(愛知県名古屋市)
- Year and Date
  2015-10-02
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26253058
[Presentation] 健康長寿を目指した糖尿病治療薬開発に向けたアディポネクチン受容体アゴニストの創製2015
- Author(s)
  岩部　美紀、山内　敏正、岩部　真人、門脇　孝
- Organizer
  第58回　日本糖尿病学会年次学術集会
- Place of Presentation
  グランプラス　セント・バレンタイン（山口県下関市）
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-26293216
[Presentation] Mutational Analyses Based on Crystal Structures of AdipoRs Facilitate understanding of NobelStructure-Function Relationships Including Adiponectin Binding and intrasellular Signal Transduction.2015
- Author(s)
  Toshimasa Yamauchi, Miki Okada-Iwabu, Masato Iwabu, Takashi Kadowaki
- Organizer
  American Diabetes Association 75th Scientific Sessions
- Place of Presentation
  ボストン(アメリカ)
- Year and Date
  2015-06-08
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26253058
[Presentation] アディポネクチンup to date2015
- Author(s)
  山内　敏正
- Organizer
  第49回糖尿病学の進歩
- Place of Presentation
  岡山コンベンションセンター
- Year and Date
  2015-02-20
- Invited
- Data Source
  KAKENHI-PROJECT-26253058
[Presentation] Crystal structure of the human adiponectin receptors2015
- Author(s)
  MIKI OKADA-IWABU, TOSHIMASA YAMAUCHI, MASATO IWABU,TAKASHI KADOWAKI
- Organizer
  第20回　アディポサイエンスシンポジウム
- Place of Presentation
  千里ライフサイエンスセンター（大阪府豊中市）
- Year and Date
  2015-08-22
- Invited
- Data Source
  KAKENHI-PROJECT-26293216
[Presentation] Pathophysiological roles of adipokine and epigenome dysregulation in obesity.2015
- Author(s)
  Toshimasa Yamauchi
- Organizer
  The 46th NIPS international Symposium
- Place of Presentation
  名古屋国際会議場(愛知県名古屋市)
- Year and Date
  2015-10-02
- Invited
- Data Source
  KAKENHI-PUBLICLY-15H01507
[Presentation] アディポネクチン受容体の抗体創薬に向けた検討と解析2015
- Author(s)
  岩部　美紀、山内　敏正、岩部　真人、門脇　孝
- Organizer
  第8回システム疾患生命科学による先端医療技術開発シンポジウム
- Place of Presentation
  東京大学医学部附属病院（東京都・文京区）
- Year and Date
  2015-02-27
- Data Source
  KAKENHI-PROJECT-26293216
[Presentation] アディポネクチン受容体の病態生理学的意義2015
- Author(s)
  山内　敏正
- Organizer
  第88回日本内分泌学会学術総会
- Place of Presentation
  ホテルニューオータニ (東京都千代田区)
- Year and Date
  2015-04-23
- Invited
- Data Source
  KAKENHI-PROJECT-26253058
[Presentation] アディポネクチン受容体アゴニストの抗糖尿病作用と寿命延長効果2014
- Author(s)
  岩部　美紀、山内　敏正、岩部　真人、門脇　孝
- Organizer
  第29回日本糖尿病合併症学会
- Place of Presentation
  都市センターホテル（東京都・千代田区）
- Year and Date
  2014-10-03
- Data Source
  KAKENHI-PROJECT-26293216
[Presentation] アディポネクチン受容体の標的分子の探索と薬・食への活用2014
- Author(s)
  山内　敏正
- Organizer
  第２回薬食国際カンファレンス
- Place of Presentation
  日本平ホテル
- Year and Date
  2014-11-06
- Invited
- Data Source
  KAKENHI-PROJECT-26253058
[Presentation] アディポネクチン受容体アゴニストの抗糖尿病作用と寿命延長効果2014
- Author(s)
  岩部　美紀、山内　敏正、岩部　真人、門脇　孝
- Organizer
  第35回日本肥満学会
- Place of Presentation
  ェニックスシーガイアリゾートコンベンションセンター（宮崎県・宮崎市）
- Year and Date
  2014-10-25
- Data Source
  KAKENHI-PROJECT-26293216
[Presentation] 大学の研究から大学発の創薬への挑戦ー若手の皆さんのこれからの楽しい研究生活に向けてー2014
- Author(s)
  岩部　美紀、山内　敏正、岩部　真人、門脇　孝
- Organizer
  2014年度臨床者育成プログラムMetabolism Research Course
- Place of Presentation
  東京大学医学部附属病院（東京都・文京区）
- Year and Date
  2014-06-06
- Invited
- Data Source
  KAKENHI-PROJECT-26293216
[Presentation] アディポネクチン受容体AdipoRの骨格筋における生理的・病態生理的意義の解明と治療への応用2014
- Author(s)
  山内　敏正
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2014-10-07
- Invited
- Data Source
  KAKENHI-PROJECT-26253058
[Presentation] A small-molecule AdipoR agonist ameliorates type 2 diabetes and prolongs the shortened lifespan2014
- Author(s)
  MIKI OKADA-IWABU, TOSHIMASA YAMAUCHI, MASATO IWABU,TAKASHI KADOWAKI
- Organizer
  第19回アディポサイエンスシンポジウム
- Place of Presentation
  里ライフサイエンスセンター（大阪府・豊中市）
- Year and Date
  2014-08-23
- Data Source
  KAKENHI-PROJECT-26293216
[Presentation] Cdkal1はWnt経路を介して脂肪細胞分化を抑制する2014
- Author(s)
  冨岡　恵、武　和巳、孫　威、脇　裕典、山内　敏正、于静、青山倫久、平池勇雄、岩部真人、岩部美紀、植木浩二郎、門脇　孝
- Organizer
  第35回日本肥満学会
- Place of Presentation
  宮崎市
- Year and Date
  2014-10-24
- Data Source
  KAKENHI-PLANNED-23126101
[Presentation] A small-molecule AdipoR agonist ameliorates type 2 diabetes and prolongs the shortened lifespan2014
- Author(s)
  MIKI OKADA-IWABU, TOSHIMASA YAMAUCHI, MASATO IWABU,TAKASHI KADOWAKI
- Organizer
  American Diabetes Association, 74th Scientific Sessions
- Place of Presentation
  SanFrancisco (USA)
- Year and Date
  2014-06-15
- Data Source
  KAKENHI-PROJECT-26293216
[Presentation] 糖尿病と肥満症2014
- Author(s)
  山内　敏正
- Organizer
  第29回日本糖尿病合併症学会
- Place of Presentation
  シェーンバッハ・サボー
- Year and Date
  2014-10-04
- Invited
- Data Source
  KAKENHI-PROJECT-26253058
[Presentation] Cdkal1はWnt経路を介して脂肪細胞分化を抑制する2014
- Author(s)
  冨岡　恵、武　和巳、孫　威、脇　裕典、山内　敏正、于静、青山倫久、平池勇雄、岩部真人、岩部美紀、植木浩二郎、門脇　孝
- Organizer
  第57回日本糖尿病学会年次学術集会
- Place of Presentation
  大阪市
- Year and Date
  2014-05-24
- Data Source
  KAKENHI-PLANNED-23126101
[Presentation] 肥満症治療新規薬物-AdipoRon を中心に-2014
- Author(s)
  山内　敏正
- Organizer
  第35回日本肥満学会
- Place of Presentation
  フェニックスシーガイアリゾートコンベンションセンター
- Year and Date
  2014-10-24
- Invited
- Data Source
  KAKENHI-PROJECT-26253058
[Presentation] Genome-wide Profiling of Brown Fat-Specific Open Regulatory Regions Identifies NFIA as a Transcriptional Regulator of Brown Fat Differentiation2014
- Author(s)
  Hironori Waki, Yuta Hiraike Jing Yu, Kana Miyake, Masahiro Nakamura, Ken Suzuki, Wei Sun, Megumi Tomioka, Yusuke Hirota, Tomohisa Aoyama, Masato Iwabu, Miki Okada-Iwabu, Kohjiro Ueki, Shuichi Tsutsumi, Hiroyuki Aburatani, Toshimasa Yamauchi and Takashi Kadowaki
- Organizer
  International Symposium for the Study of Obesity “Molecular Basis and Disorders of Control of Appetite and Fat Accumulation″
- Place of Presentation
  Miyazaki, Japan
- Year and Date
  2014-10-26
- Invited
- Data Source
  KAKENHI-PLANNED-23126101
[Presentation] A small-molecule AdipoR agonist ameliorates type 2 diabetes and prolongs the shortened lifespan2014
- Author(s)
  MIKI OKADA-IWABU, TOSHIMASA YAMAUCHI, MASATO IWABU,TAKASHI KADOWAKI
- Organizer
  9th Metabolic Syndrome, Type 2 Diabetes and Atherosclerosis Congress
- Place of Presentation
  国立京都国際会館（京都府・京都市）
- Year and Date
  2014-09-23
- Data Source
  KAKENHI-PROJECT-26293216
[Presentation] アディポネクチン受容体アゴニストの抗糖尿病作用と寿命延長効果2014
- Author(s)
  岩部　美紀、山内　敏正、岩部　真人、門脇　孝
- Organizer
  第57回日本糖尿病学会年次学術集会
- Place of Presentation
  ホテルNCB（大阪府・大阪市）
- Year and Date
  2014-05-24
- Data Source
  KAKENHI-PROJECT-26293216
[Presentation] アディポネクチン受容体を標的にした健康長寿薬買う初への挑戦2014
- Author(s)
  山内　敏正
- Organizer
  第19回アディポサイエンス・シンポジウム
- Place of Presentation
  千里ライフサイエンスセンター
- Year and Date
  2014-08-23
- Invited
- Data Source
  KAKENHI-PROJECT-26253058
[Presentation] Genome-wide Profiling of Brown Fat-Specific Open Regulatory Regions Identifies NFIA as a Transcriptional Regulator of Brown Fat Muscle Cell Lineage Specification2014
- Author(s)
  Hironori Waki, Yuta Hiraike, Jing Yu, Kana Miyake, Masahiro Nakamura, Ken Suzuki, Kohjiro Ueki, Shuichi Tsutsumi, Hiroyuki Aburatani, Toshimasa Yamauchi, Takashi Kadowaki
- Organizer
  9th Metabolic Syndrome, Type 2 Diabetes and Atherosclerosis Congress
- Place of Presentation
  Kyoto, Japan
- Year and Date
  2014-09-13
- Data Source
  KAKENHI-PLANNED-23126101
[Presentation] 白色・褐色脂肪細胞におけるクロマチン構造変化とエピゲノム制御の役割2014
- Author(s)
  脇裕典、平池勇雄、于静、中村正裕、青山倫久、孫威、鈴木顕、若林賢一、井上剛、武和巳、冨岡恵、三宅加奈、廣田雄輔、岩部真人、岩部美紀、杉山拓也、和田洋一郎、植木浩二郎、堤　修一、油谷浩幸、山内敏正、門脇孝
- Organizer
  第35回日本肥満学会　シンポジウム
- Place of Presentation
  宮崎市
- Year and Date
  2014-10-25
- Invited
- Data Source
  KAKENHI-PLANNED-23126101
[Presentation] アディポネクチン受容体をターゲットにした糖尿病治療薬開発の試み2014
- Author(s)
  岩部　美紀、山内　敏正、岩部　真人、門脇　孝
- Organizer
  第87回日本内分泌学会学術集会
- Place of Presentation
  福岡国際会議場（福岡県・福岡市）
- Year and Date
  2014-04-24
- Data Source
  KAKENHI-PROJECT-26293216
[Presentation] Cdkal1はWnt経路を介して脂肪細胞分化を抑制する2013
- Author(s)
  脇　裕典、武　和巳、山内敏正、孫威、岩部真人、岩部美紀、植木浩二郎、門脇　孝
- Organizer
  第56回日本糖尿病学会年次学術総会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PLANNED-23126101
[Presentation] Cdkal1はWnt経路を介して脂肪細胞分化を抑制する2013
- Author(s)
  脇裕典、武和巳、山内敏正、孫威、岩部真人、岩部美紀、植木浩二郎、門脇孝
- Organizer
  日本糖尿病学会　第54回年次学術集会
- Place of Presentation
  熊本
- Year and Date
  2013-05-16
- Data Source
  KAKENHI-PLANNED-23126101
[Presentation] CDK5 Regulatory Subunit-Associated Protein 1-Like 1 (Cdkal1) Negatively Regulates Adipocyte Differentiation through Activation of the Wnt Pathway2013
- Author(s)
  Kazumi Take, Hironori Waki, Toshimasa Yamauchi, Wei Sun, Jing Yu, Masato Iwabu, Miki Okada-Iwabu, Kohjiro Ueki and Takashi Kadowaki
- Organizer
  Keystone Symposia, Adipose Tissue Biology (J5)
- Place of Presentation
  Keystone, Colorado USA
- Year and Date
  2013-01-27
- Data Source
  KAKENHI-PLANNED-23126101
[Presentation] Cdkal1はWnt経路を介して脂肪細胞分化を抑制する2013
- Author(s)
  武　和巳、脇　裕典、山内敏正、孫威、岩部真人、岩部美紀、植木浩二郎、門脇　孝
- Organizer
  第18回アディポサイエンス・シンポジウム
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PLANNED-23126101
[Presentation] CDK5 Regulatory Subunit-Associated Protein 1-Like 1 (Cdkal1) Negatively Regulates Adipocyte Differentiation through Activation of the Wnt Pathway2013
- Author(s)
  Kazumi Take, Hironori Waki, Toshimasa Yamauchi, Wei Sun, Jing Yu, Masato Iwabu, Miki Okada-Iwabu, Kohjiro Ueki and Takashi Kadowaki
- Organizer
  American Diabetes Association, 73rd Scientific Session
- Place of Presentation
  Chicago, Illinois USA
- Year and Date
  2013-06-21
- Data Source
  KAKENHI-PLANNED-23126101
[Presentation] CDK5 Regulatory Subunit-Associated Protein 1-Like 1 (Cdkal1) Negatively Regulates Adipocyte Differentiation through Activation of the Wnt Pathway2013
- Author(s)
  Kazumi Take, Hironori Waki, Toshimasa Yamauchi, Wei Sun, Jing Yu, Masato Iwabu, Miki Okada-Iwabu, Kohjiro Ueki, Takashi Kadowaki.
- Organizer
  American Diabetes Association 73nd Scientific Sessions
- Place of Presentation
  Chicago, IL, 米国
- Data Source
  KAKENHI-PLANNED-23126101
[Presentation] Cdkal1はWnt径路を介して脂肪細胞分化を抑制する2013
- Author(s)
  孫　威、武　和巳、脇　裕典、山内敏正、岩部真人、岩部美紀、植木浩二郎、門脇孝
- Organizer
  第34回日本肥満学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PLANNED-23126101
[Presentation] Translational Science on Adiponectin and AdipoR2012
- Author(s)
  Toshimasa Yamauchi
- Organizer
  Translational Science and Epdemiology on Adipomedicine; From Lipodystrophy to Obesity
- Place of Presentation
  京都大学医学部芝蘭会館
- Year and Date
  2012-10-13
- Data Source
  KAKENHI-ORGANIZER-22126001
[Presentation]2010
- Author(s)
  山内敏正
- Organizer
  新学術領域「食欲と脂肪蓄積の制御と破綻の分子基盤の解明」
- Place of Presentation
  千里ライフサイエンスセンター(豊中市)
- Year and Date
  2010-11-20
- Data Source
  KAKENHI-PLANNED-22126007
[Presentation] 代謝に重要な各組織におけるアディポネクチン受容体を介した細胞内情報伝達の解析2010
- Author(s)
  山内敏正、岩部美紀、岩部真人、窪田直人、植木浩二郎、門脇孝
- Organizer
  第31回日本肥満学会
- Place of Presentation
  前橋
- Year and Date
  2010-10-02
- Data Source
  KAKENHI-PROJECT-20390254
[Presentation] Pathophysiological Roles of AdipoR2 in Endothelial Cells and AdipoR1 in Macrophages in the Prevention of Atherosclerosis.2010
- Author(s)
  岩部美紀, 山内敏正, 岩部真人, 窪田直人, 植木浩二郎, 門脇孝
- Organizer
  第3回Insulin Resistance in Metabolic Disease Forum
- Place of Presentation
  ホテル日航福岡(福岡市)
- Year and Date
  2010-11-21
- Data Source
  KAKENHI-PLANNED-22126007
[Presentation] 代謝に重要な各組織におけるアティポネクチン受容体を介した細胞内情報伝達の解析2010
- Author(s)
  山内敏正, 岩部美紀, 岩部真人, 窪田直人, 植木浩二郎, 門脇孝
- Organizer
  第31回日本肥満学会
- Place of Presentation
  煥乎堂(前橋市)
- Year and Date
  2010-10-02
- Data Source
  KAKENHI-PROJECT-20390254
[Presentation] Pathophysiological roles of adiponectin and AdipoRs in metabolic syndrome2010
- Author(s)
  山内敏正
- Organizer
  第53回日本糖尿病学会年次学術集会シンポジウムProgress in Metabolic Syndrome Research 2010
- Place of Presentation
  岡山全日空ホテル(岡山市)
- Year and Date
  2010-05-27
- Data Source
  KAKENHI-PROJECT-20390254
[Presentation] Adiponectin and AdipoR1 regulate PGC-1alpha and mitochondria by Ca2+ signalling and AMPK/SIRT1 like exercise.2010
- Author(s)
  Yamauchi T, Iwabu M, Okada-Iwabu M, Ueki K, Kadowaki T
- Organizer
  46^<th> Annual Meeting of the European Association for the Study of Diabetes.
- Place of Presentation
  Stockholm
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-20229008
[Presentation] Signal Transduction Mechanisms by Which Adiponectin/AdipoR1 Active AMP K, SIRT1 and PGC-lalpha, Leading to Increased Mitochondrial Bioenergetics in Muscle Cells.2010
- Author(s)
  Toshimasa Yamauchi, Masato Iwabu, Miki Iwahu, Kohjiro Ueki, Takashi Kadowaki
- Organizer
  The 70^<th> Scientific Sessions of the American Diabetes Association 2010
- Place of Presentation
  Florida, USA
- Year and Date
  2010-06-28
- Data Source
  KAKENHI-PROJECT-20390254
[Presentation] Progress in Metabolic Syndrome Research 2010「Pathophysiological roles of adiponectin and AdipoRs in metabolic syndrome」2010
- Author(s)
  山内敏正
- Organizer
  第53回日本糖尿病学会年次学術集会
- Place of Presentation
  岡山
- Year and Date
  2010-05-27
- Data Source
  KAKENHI-PROJECT-20390254
[Presentation] Adiponectin and AdipoRl regulate PGC-lalpha and mitochondria by Ca^<2+> signalling and AMPK/SIRTl like exercise.2010
- Author(s)
  Yamauchi T. Iwabu M. Okada-Iwabu M, Ueki K, Kadowaki T
- Organizer
  6^<th>Annual Meeting of the European Association for the Study of Diabetes.
- Place of Presentation
  Stockholm, Sweden
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-20229008
[Presentation] Signal Transduction Mechanisms by Which Adiponectin/AdipoR1 Active AMPK, SIRT1 and PGC-1alpha, Leading to Increased Mitochondrial Bioenergetics in Muscle Cells.2010
- Author(s)
  山内敏正, 岩部真人, 岩部美紀, 植木浩二郎, 門脇孝
- Organizer
  The 70^<th> Scientific Sessions of the American Diabetes Association 2010
- Place of Presentation
  Florida, USA
- Year and Date
  2010-06-28
- Data Source
  KAKENHI-PROJECT-20390254
[Presentation] Targeted Disruption of Adiponectin Receptor AdipoR2 in Endothelial Cells Reduced PPARgamma and Increased Neointimal Formation.2009
- Author(s)
  山内敏正, 岩部美紀, 岩部真人, 窪田直人, 植木浩二郎, 門脇孝
- Organizer
  The 69^<th> Scientific Sessions of the American Diabetes Association 2009
- Place of Presentation
  Louisiana, USA
- Year and Date
  2009-06-07
- Data Source
  KAKENHI-PROJECT-20390254
[Presentation] アディポネクチン受容体AdipoRと2型糖尿病2009
- Author(s)
  山内敏正, 門脇孝
- Organizer
  第30回日本肥満学会
- Place of Presentation
  浜松
- Year and Date
  2009-10-09
- Data Source
  KAKENHI-PROJECT-21659228
[Presentation] AdipoR欠損マウス及び培養細胞を用いた代謝に重要な各組織におけるアディポネクチン受容体を介した細胞内情報伝達の解析2009
- Author(s)
  山内敏正、岩部真人、岩部美紀、船田雅昭、山口麻美子、窪田直人、植木浩二郎、門脇孝
- Organizer
  第52回日本糖尿病学会年次学術集会
- Place of Presentation
  大阪
- Year and Date
  2009-05-23
- Data Source
  KAKENHI-PROJECT-20390254
[Presentation] AdipoR欠損マウス及び培養細胞を用いた代謝に重要な各組織におけるアディポネクチン受容体を介した細胞内情報伝達の解析2009
- Author(s)
  山内敏正, 岩部真人, 岩部美紀, 船田雅昭, 山口麻美子, 窪田直人, 植木浩二郎, 門脇孝
- Organizer
  第52回日本糖尿病学会年次学術集会
- Place of Presentation
  大阪
- Year and Date
  2009-05-23
- Data Source
  KAKENHI-PROJECT-21659228
[Presentation] Muscle-Specific Disruption of AdipoR1 Reduced pAMPK PGC-1Mitochondrial Biogenesis2009
- Author(s)
  山内敏正, 岩部真人, 岩部美紀, 窪田直人, 植木浩二郎, 門脇孝
- Organizer
  Slow Twitch Muscle Fibers, Insulin Sensitivity and Running Endurance. The 69^<th> Scientific Sessions of the American Diabetes Association 2009
- Place of Presentation
  Louisiana, USA
- Year and Date
  2009-06-07
- Data Source
  KAKENHI-PROJECT-20390254
[Presentation] アディポネクチン受容体AdipoRと2型糖尿病2009
- Author(s)
  山内敏正、門脇孝
- Organizer
  第30回日本肥満学会
- Place of Presentation
  浜松
- Year and Date
  2009-10-09
- Data Source
  KAKENHI-PROJECT-20390254
[Presentation] インスリン感受性調節における血管内皮細胞インスリンシグナルの役割2009
- Author(s)
  窪田直人,窪田哲也,山口真一,山内敏正,槙木浩二郎,門脇孝
- Organizer
  第23回日本糖尿病・肥満動物学会年次学術集会
- Place of Presentation
  岡山
- Year and Date
  2009-02-13
- Data Source
  KAKENHI-PROJECT-19591037
[Presentation] Targeted Disruption of Adiponectin Receptor AdipoR2 in Endothelial Cells Reduced PPARgamma and Increased Neointimal Formation.2009
- Author(s)
  山内敏正, 岩部真人, 岩部美紀, 窪田直人, 植木浩二郎, 門脇孝
- Organizer
  The 69th Scientific Sessions of the American Diabates Association 2009
- Place of Presentation
  New Orleans U.S.A.
- Year and Date
  2009-06-07
- Data Source
  KAKENHI-PROJECT-20390254
[Presentation] Targeted Disruption of Adiponectin Receptor AdipoR2 in Endothelial Cell is Reduced PPARgamma and Increased Neointimal Formation.2009
- Author(s)
  山内敏正, 岩部真人, 岩部美紀, 窪田直人, 植木浩二郎, 門脇孝
- Organizer
  The 69th Scientific Sessions of the American Dia betes Association 2009
- Place of Presentation
  New Orleans USA
- Year and Date
  2009-06-07
- Data Source
  KAKENHI-PROJECT-21659228
[Presentation] シンポジウム6脂肪組織における炎症とストレス応答Adiponectin Receptors-New InsightsinthePathogenesis of Obesity-linked Insulin Resistance and Metabolic Syndrome2008
- Author(s)
  山内敏正
- Organizer
  第51回日本糖尿病学会年次学術集会
- Place of Presentation
  東京
- Year and Date
  2008-05-23
- Data Source
  KAKENHI-PROJECT-20390254
[Presentation] Insulin signaling defect in endothelial cells causesskeletal muscle insulin resistance2008
- Author(s)
  Kubota N, Kubota T, Kumagai H, Yamauchi T, Ueki K, Kadowaki T
- Organizer
  第40回日本動脈硬化学会総会・学術集会
- Place of Presentation
  茨城
- Year and Date
  2008-07-11
- Data Source
  KAKENHI-PROJECT-19591037
[Presentation] Dynamic functional relay between insulin receptor substrate-1 and -2 in hepatic insulin signaling during fasting and feeding2008
- Author(s)
  Naoto Kubota、Tetsuya Kubota、Toshimasa Yamauchi、Kohjiro Ueki、Takashi Kadowaki
- Organizer
  第1回Insulin Resistance in Metabolic Disease Forum
- Place of Presentation
  大阪
- Year and Date
  2008-09-20
- Data Source
  KAKENHI-PROJECT-20390254
[Presentation] Physiological roles of adiponectin /AdipoRs in skeletal musele bioenergetics -Disruption of adipoRs resulted in mitochon drial dysfunction in skeletal muscle.2008
- Author(s)
  Masato Iwabu, Toshimasa Yamauchi, Miki Okada-Iwabu, Kohjiro Ueki, Takashi Kadowak
- Organizer
  第1回InsulinResistance in Metabolic Disease Forum
- Place of Presentation
  大阪
- Year and Date
  2008-09-20
- Data Source
  KAKENHI-PROJECT-20390254
[Presentation] Insulin signaling in endothelial cells participates in the regulation of skeletal muscle insulin sensitivity2008
- Author(s)
  Kubota T, Kubota N, Yamaguchi S, Inoue M, Veki K, Kadowaki T
- Organizer
  The 10th Symposium on Molecular Diabetology in Asia
- Place of Presentation
  Guangzhou
- Year and Date
  2008-10-29
- Data Source
  KAKENHI-PROJECT-19591037
[Presentation] 2型糖尿病の分子メカニズムと治療戦略2008
- Author(s)
  山内敏正
- Organizer
  第51回日本糖尿病学会年次学術集会
- Place of Presentation
  東京
- Year and Date
  2008-05-22
- Data Source
  KAKENHI-PROJECT-20390254
[Presentation] Dynamic functional relay between insulin receptor substrate-1 and -2 in hepatic insulin signaling during fasting and feeding.2008
- Author(s)
  Kubota N, Kubota T, Yamauchi T, Ueki K, Kadowaki T
- Organizer
  The 4th Scientific Meeting of Asia-Pacific Diabetes and Obesity Study Group
- Place of Presentation
  Japan(Osaka)
- Year and Date
  2008-08-20
- Data Source
  KAKENHI-PROJECT-19591037
[Presentation] シンポジウム6:脂肪組織における炎症とストレス応答Adiponectin Receptors-New Insights in the Pathogenesis of Obesity-linked Insulin Resistance and Metabolic Syndrome-2008
- Author(s)
  山内敏正
- Organizer
  第51回日本糖尿病学会年次学術集会
- Place of Presentation
  東京
- Year and Date
  2008-05-23
- Data Source
  KAKENHI-PROJECT-20390254
[Presentation] 肝臓の糖代謝におけるIRS-1、IRS-2の役割の検討2008
- Author(s)
  窪田直人,窪田哲也,伊藤晋介,山内敏正,植木浩二郎,門脇孝
- Organizer
  第13回アディポサイエンス研究会
- Place of Presentation
  大阪
- Year and Date
  2008-08-22
- Data Source
  KAKENHI-PROJECT-19591037
[Presentation] (糖・脂質代謝1-3)アディポネクチン/AdipoRの生理的・病態生理的意義2008
- Author(s)
  山内敏正
- Organizer
  第81回日本内分泌学会学術総会
- Place of Presentation
  青森
- Year and Date
  2008-05-17
- Data Source
  KAKENHI-PROJECT-20390254
[Presentation] Dynamic functional relay between insulin receptor substrate-1 and -2 in hepatic insulin signaling during fasting and feeding.2008
- Author(s)
  Kubota N, Kubota T, Yamauchi T, Ueki K, Kadowaki T
- Organizer
  The 1st Insulin Resistance in Metabolic Disease Forum
- Place of Presentation
  Japan(Osaka)
- Year and Date
  2008-09-20
- Data Source
  KAKENHI-PROJECT-19591037
[Presentation] シンポジウム1:肥満脂肪細胞の病態:肥満脂肪組織とアディポネクチン受容体2008
- Author(s)
  山内敏正、門脇孝
- Organizer
  第29回日本肥満学会
- Place of Presentation
  大分
- Year and Date
  2008-10-17
- Data Source
  KAKENHI-PROJECT-20390254
[Presentation] アディポネクチン/AdipoRの生理的・病態生理的意義2008
- Author(s)
  山内敏正
- Organizer
  第81回日本内分泌学会学術総会
- Place of Presentation
  青森
- Year and Date
  2008-05-17
- Data Source
  KAKENHI-PROJECT-20390254
[Presentation] シンポジウム1肥満脂肪細胞の病態肥満脂肪組織とアディポネクチン受容体2008
- Author(s)
  山内敏正、門脇孝
- Organizer
  第29回日本肥満学会
- Place of Presentation
  大分
- Year and Date
  2008-10-17
- Data Source
  KAKENHI-PROJECT-20390254
[Presentation] Physiological roles of adiponectin/AdipoRs in skeletal muscle bioenergetics-Disruption of adipoRs resulted in mitochondrial dysfunction in skeletal muscle2008
- Author(s)
  岩部真人、山内敏正、岩部美紀、植木浩二郎、門脇孝
- Organizer
  第1回Insulin Resistance in Metabolic Disease Forum
- Place of Presentation
  大阪
- Year and Date
  2008-09-20
- Data Source
  KAKENHI-PROJECT-20390254
[Presentation] Dynamic functional relay between insulin receptor substrate-1 and -2 in hepatic insulin signaling during fasting and feeding.2008
- Author(s)
  Naoto Kubota, Tetsuya Kubota, Toshimasa Yamauchi, Kohjiro Ueki, Takashi Kadowaki.
- Organizer
  第1回Insulin Resistance in Metabolic Disease Forum
- Place of Presentation
  大阪
- Year and Date
  2008-09-20
- Data Source
  KAKENHI-PROJECT-20390254
[Presentation] IRS-2欠損膵β細胞株の樹立2008
- Author(s)
  高本偉碩,窪田直人,橋本信嗣,峯山智佳,窪田哲也,伊藤晋介,山内敏正,植木浩二郎,宮崎純一,門脇孝
- Organizer
  第51回日本糖尿病学会年次学術集会
- Place of Presentation
  東京
- Year and Date
  2008-05-22
- Data Source
  KAKENHI-PROJECT-19591037
[Presentation] インスリン抵抗性発症における血管と骨格筋のネットワーク機構の解明2008
- Author(s)
  窪田哲也,窪田直人,熊谷洋紀,小園秀樹,高橋雄大,杉薫,山内敏正,植木浩二郎,門脇孝
- Organizer
  第51回日本糖尿病学会年次学術集会
- Place of Presentation
  東京
- Year and Date
  2008-05-22
- Data Source
  KAKENHI-PROJECT-19591037
[Presentation] メタボリックシンドロームアディポネクチン/AdipoRの病態生理的意義2007
- Author(s)
  山内敏正, 原一雄, 窪田直人, 植木浩二郎, 戸辺一之, 門脇孝
- Organizer
  第44回日本臨床分子医学会学術総会
- Place of Presentation
  和歌山
- Year and Date
  2007-07-20
- Data Source
  KAKENHI-PROJECT-18390270
[Presentation] Pathophysiological roles of Adiponectin and Adiponectin Receptors2007
- Author(s)
  Toshmasa Yamauchi, Naoto Kubota, Kazuo Hara, Kohjio Ueki, Kazuyuki Tobe and Takashi Kadowaki
- Organizer
  Okazaki Symposium 2007 on Obesity & Diabetes
- Place of Presentation
  Okazaki
- Year and Date
  2007-04-14
- Data Source
  KAKENHI-PROJECT-18390270
[Presentation] Pathophysiological roles of Adiponectin and Adiponectin Receptors2007
- Author(s)
  Toshimasa Yamauchi, Naoto Kubota, Kazuo Hara, Kohjiro Ueki, Kazuyuki Tobe, Takashi Kadowaki
- Organizer
  Okazaki Symposium 2007 on Obesity & Diabetes
- Place of Presentation
  Okazaki
- Year and Date
  2007-04-14
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15081202
[Presentation] アディポネクチン受容体の生理的・病態生理的意義の解明2007
- Author(s)
  山内敏正
- Organizer
  第50回日本糖尿病学会年次学術集会
- Place of Presentation
  仙台
- Year and Date
  2007-05-25
- Data Source
  KAKENHI-PROJECT-18390270
[Presentation] メタボリックシンドローム-その分子病態-2007
- Author(s)
  山内敏正
- Organizer
  第27回日本医学会総会
- Place of Presentation
  大阪
- Year and Date
  2007-04-07
- Data Source
  KAKENHI-PROJECT-18390270
[Presentation] シンポジウム「アディポネクチン・アディポネクチン受容体の生理的・病態生理的意義」2007
- Author(s)
  山内敏正
- Organizer
  第50回日本糖尿病学会年次学術集会
- Place of Presentation
  仙台
- Year and Date
  2007-05-25
- Data Source
  KAKENHI-PROJECT-18390270
[]
[]
[]
[]
[]
[]
[]
[]
[]

1. KADOWAKI Takashi (30185889)

# of Collaborated Projects: 22 results

# of Collaborated Products: 248 results
2. KUBOTA Naoto (50396719)

# of Collaborated Projects: 12 results

# of Collaborated Products: 111 results
3. TOBE Kazuyuki (30251242)

# of Collaborated Projects: 9 results

# of Collaborated Products: 31 results
4. IWABU Masato (30557236)

# of Collaborated Projects: 9 results

# of Collaborated Products: 81 results
5. HARA Kazuo (50359600)

# of Collaborated Projects: 8 results

# of Collaborated Products: 49 results
6. IWABU Miki (70392529)

# of Collaborated Projects: 8 results

# of Collaborated Products: 81 results
7. UEKI Kojiro (00396714)

# of Collaborated Projects: 7 results

# of Collaborated Products: 39 results
8. TERAUCHI Yasuo (40359609)

# of Collaborated Projects: 6 results

# of Collaborated Products: 3 results
9. HOSODA Kiminori (40271598)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. WAKI Hironori (00466765)

# of Collaborated Projects: 2 results

# of Collaborated Products: 29 results
11. KANGAWA Kenji (00112417)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. KOJIMA Masayasu (20202062)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. SHIODA Seiji (80102375)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. MINOKOSHI Yasuhiko (10200099)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. KATAGIRI Hideki (00344664)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. FUNAHASHI Tohru (60243234)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. NAKAZATO Masamitsu (10180267)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. SHIMIZU Hiroyuki (20251100)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. OGAWA Wataru (40294219)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. TOKOYAMA Shigeyuki (00159229)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. Nakagami Gojiro (70547827)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 中村耕三 (60126133)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 緒方直史 (10361495)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 原慶宏 (00422296)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 村上元昭 (50396751)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 深井厚 (20422298)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 門脇孝 (30185899)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 関野正樹 (20401036)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 栗田昌和 (20424111)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. 南豪 (70731834)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. 麦田裕子 (00804874)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. 峰松健夫 (00398752)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
33. 真田弘美 (50143920)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. SUZUKI Ryo

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
35. ETO Kazuhiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
36. 江頭一弘

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
37. SHOJIMA Nobuhiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 5 results
38. YAMAJI Taiki

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
39. 三木隆司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
40. 石垣泰

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
41. 油谷浩幸

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
42. 戸田郷太郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
43. 熊谷英敏

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
44. 池田祐一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
45. 橋本唯史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
46. 菅原真衣

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
47. 清水孝雄

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Yamauchi Toshimasa 山内 敏正

YAMAUCHI Toshimasa 山内 敏正

Research Projects

Research Products

Co-Researchers

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the cause of diabetes in the Japanese population using whole genome information and development of diagnostic and therapeutic methods using iPS cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

生活習慣病と組織幹細胞老化の連関メカニズム解明とその制御による予防・治療法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Pathophysiological roles of adipokines in the regulation of gut microbiota in life-style related diseasesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

運動模倣薬としてのアディポネクチン受容体活性化薬の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

新規転写因子・エピゲノムネットワークによる脂肪蓄積制御メカニズムの解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Yamauchi Toshimasa 山内敏正

YAMAUCHI Toshimasa 山内敏正