Misaka Takumi 三坂巧

… Alternative Names

MISAKA Takumi 三坂巧

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Researcher Number	40373196
Other IDs	https://orcid.org/0000-0002-9547-5767
Affiliation (Current)	2025: 東京大学, 大学院農学生命科学研究科(農学部), 准教授
Affiliation (based on the past Project Information) *help	2016 – 2024: 東京大学, 大学院農学生命科学研究科(農学部), 准教授 2015 – 2016: 東京大学, 大学院農学生命科学研究科, 准教授 2015: 東京大学, 農学生命科学研究科, 准教授 2011: The University of Tokyo, 農学生命科学研究科, 准教授 2007 – 2010: The University of Tokyo, Graduate School of Agricultural and Life Sciences, Associate professor … More 2006: 東京大学, 大学院農学生命科学研究科, 講師 2004 – 2005: 東京大学, 大学院・農学生命科学研究科, 講師 2004: 生理学研究所, 分子生理研究系, 助手 Less
Review Section/Research Field	Principal Investigator Food science / Basic Section 38050:Food sciences-related / Applied molecular and cellular biology / Medium-sized Section 38:Agricultural chemistry and related fields / General physiology Except Principal Investigator Medium-sized Section 38:Agricultural chemistry and related fields / Eating habits / Food science / Applied molecular and cellular biology
Keywords	Principal Investigator 食品 / 味覚 / 遺伝子 / 嗜好性 / 生体分子 / 食品機能 / 受容体 / 味覚受容体 / 培養細胞 / 阻害剤 … More / 活性調節 / ｐH / 蛍光イメージング / pH / センサー / 味物質 / 分子間相互作用 / GTP結合タンパク質 / ダイナミン / Gタンパク質 / 視神経萎縮症 / ミトコンドリア … More Except Principal Investigator 味覚受容体 / 鳥類 / 食性 / GPCR / 食と健康 / SKn-1マウス / 脳腸軸 / 食と栄養 / 食品機能 / エネルギー代謝 / 味物質科学 / 刷子細胞 / Skn-1マウス / 味覚シグナル / 遺伝子破壊マウス / 栄養素 / 代謝 / 消化管 / 受容体 / Feeding behavior / Taste signal transmission / DNA microarray / Transgenic animals / Taste system / モデル魚 / 味覚行動 / ホスホリパーゼCβ2 / 脳・神経 / シグナル伝達 / ゲノム / 食品 / 味覚 / 魚T2Rs / アミノ酸 / 魚T2R / 魚T1Rs / トランスジェニックメダカ / 摂食行動 / 味覚伝道路 / DNAマイクロアレイ / トランスジェニック動物 / 味覚システム Less

新生仔期の呈味刺激による味覚認知回路の質的変化の検出―幼少期の食事は脳を変える？Principal Investigator
- Principal Investigator
  
  三坂巧
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 38:Agricultural chemistry and related fields
- Research Institution
  The University of Tokyo
嗜好味受容体におけるリガンド選択性・感受性を決定する因子の構造活性相関による同定Principal Investigator
- Principal Investigator
  
  三坂巧
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 38050:Food sciences-related
- Research Institution
  The University of Tokyo
Improvement of the taste measurement techniques using taste receptor-expressing cells and characterization of natural compounds contributing to the taste enhancer/suppressorPrincipal Investigator
- Principal Investigator
  
  Misaka Takumi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 38050:Food sciences-related
- Research Institution
  The University of Tokyo
Relationship between diversification of eating habits and taste receptor functions using birds as models
- Principal Investigator
  
  Ishimaru Yoshiro
- Project Period (FY)
  2018 – 2023
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
- Review Section
  
  Medium-sized Section 38:Agricultural chemistry and related fields
- Research Institution
  Meiji University
Characterization of chemical compounds contributing to the taste enhancer/suppressor using the taste receptor-expressing cells and examination of those molecular mechanismsPrincipal Investigator
- Principal Investigator
  
  MISAKA Takumi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Food science
- Research Institution
  The University of Tokyo
Construction of a novel fluorescent measurement system to evaluate pH values in fluorescent imaging analysisPrincipal Investigator
- Principal Investigator
  
  MISAKA Takumi
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Applied molecular and cellular biology
- Research Institution
  The University of Tokyo
Peripheral Response to Tastant Signals and Central Cognition for Analysis of Their Coordination and its Application to the Science of Food for Life
- Principal Investigator
  
  Abe Keiko
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Eating habits
- Research Institution
  The University of Tokyo
Functional analysis of cells expressing taste-related genes in the gastrointestinal tract
- Principal Investigator
  
  ISHIMARU YOSHIRO
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Food science
- Research Institution
  The University of Tokyo
ヒト味覚受容体発現細胞を用いた味の相乗・相殺効果の分子メカニズムの解析Principal Investigator
- Principal Investigator
  
  三坂巧
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Food science
- Research Institution
  The University of Tokyo
味物質の呈味持続性を規定する因子の探索Principal Investigator
- Principal Investigator
  
  三坂巧
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Food science
- Research Institution
  The University of Tokyo
Construction of a novel taste sensor using the taste receptor protein of vertebrate originPrincipal Investigator
- Principal Investigator
  
  MISAKA Takumi
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Applied molecular and cellular biology
- Research Institution
  The University of Tokyo
味蕾細胞-味神経細胞間における情報伝達機構の解明を目指した初代共培養系の確立Principal Investigator
- Principal Investigator
  
  三坂巧
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Food science
- Research Institution
  The University of Tokyo
脊椎動物由来味覚受容体の構造機能連関を基盤とした味物質受容機構の体系的解析Principal Investigator
- Principal Investigator
  
  三坂巧
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Food science
- Research Institution
  The University of Tokyo
高分子量Gタンパク質mOPA1によるミトコンドリア形態変化機構の細胞生理学的解析Principal Investigator
- Principal Investigator
  
  三坂巧
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General physiology
- Research Institution
  The University of Tokyo
  National Institute for Physiological Sciences
Development of Sensory Genomics and Basic Analysis on Taste Bioinformation Technology
- Principal Investigator
  
  ABE Keiko
- Project Period (FY)
  2004 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Applied molecular and cellular biology
- Research Institution
  The University of Tokyo

[Journal Article] Effect of salivary gland removal on taste preference in mice2024
- Author(s)
  Narukawa Masataka、Matsuda Rina、Watari Ippei、Ono Takashi、Misaka Takumi
- Journal Title
  
  Pflugers Archiv - European Journal of Physiology
  
  Volume: 476 Issue: 1 Pages: 111-121
- DOI
  10.1007/s00424-023-02873-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K19128, KAKENHI-PROJECT-20K10200, KAKENHI-PROJECT-23K23559
[Journal Article] Allosteric modulation of the fish taste receptor type 1 (T1R) family by the extracellular chloride ion2023
- Author(s)
  Goda Ryusei、Watanabe Soichi、Misaka Takumi
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1 Pages: 16348-16348
- DOI
  10.1038/s41598-023-43700-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K23549
[Journal Article] Zebrafish and medaka T1R (taste receptor type 1) proteins mediate highly sensitive recognition of L-proline2023
- Author(s)
  Goda, R., Watanabe, S., and Misaka, T.
- Journal Title
  
  FEBS Open Bio
  
  Volume: 13 Issue: 3 Pages: 468-477
- DOI
  10.1002/2211-5463.13558
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K23549
[Journal Article] Modeling the structure of the transmembrane domain of T1R3, a subunit of the sweet taste receptor, with neohesperidin dihydrochalcone using molecular dynamics simulation2023
- Author(s)
  Nakagita Tomoya、Matsuya Takumi、Narukawa Masataka、Kobayashi Takuya、Hirokawa Takatsugu、Misaka Takumi
- Journal Title
  
  Bioscience, Biotechnology, and Biochemistry
  
  Volume: 87 Issue: 12 Pages: 1470-1477
- DOI
  10.1093/bbb/zbad133
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K05080, KAKENHI-PROJECT-23K23549
[Journal Article] 祖先の甘味感覚獲得がもたらした鳴禽類の繁栄2022
- Author(s)
  戸田安香、中北智哉、早川卓志、石丸喜朗、三坂巧、松村秀一
- Journal Title
  
  Japanese Scientists in Science 2021
  
  Volume: N/A Pages: 36-36
- Data Source
  KAKENHI-PROJECT-18KK0166
[Journal Article] 脊椎動物における味覚の多様性とその遺伝的要因2022
- Author(s)
  戸田安香、石丸喜朗、三坂巧
- Journal Title
  
  科学
  
  Volume: 92 Pages: 1046-1050
- Data Source
  KAKENHI-PROJECT-18KK0166
[Journal Article] Evolution of the primate glutamate taste sensor from a nucleotide sensor2021
- Author(s)
  Toda Yasuka、Hayakawa Takashi、Itoigawa Akihiro、Kurihara Yosuke、Nakagita Tomoya、Hayashi Masahiro、Ashino Ryuichi、Melin Amanda D.、Ishimaru Yoshiro、Kawamura Shoji、Imai Hiroo、Misaka Takumi
- Journal Title
  
  Current Biology
  
  Volume: 31 Issue: 20 Pages: 4641-4649
- DOI
  10.1016/j.cub.2021.08.002
- NAID
  120007166025
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16241, KAKENHI-PUBLICLY-20H04987, KAKENHI-PROJECT-18H04005, KAKENHI-PROJECT-19H02907, KAKENHI-PROJECT-19H02915, KAKENHI-PROJECT-20H02941, KAKENHI-PROJECT-21KK0130
[Journal Article] Characterization of the human bitter taste receptor response to sesquiterpene lactones from edible Asteraceae species and suppression of bitterness through pH control2021
- Author(s)
  Yanagisawa, T., and Misaka, T.
- Journal Title
  
  ACS Omega
  
  Volume: 6 Issue: 6 Pages: 4401-4407
- DOI
  10.1021/acsomega.0c05599
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H02907
[Journal Article] Early origin of sweet perception in the songbird radiation2021
- Author(s)
  Toda Yasuka、Ko Meng-Ching、Liang Qiaoyi、Miller Eliot T.、Rico-Guevara Alejandro、Nakagita Tomoya、Sakakibara Ayano、Uemura Kana、Sackton Timothy、Hayakawa Takashi、Sin Simon Yung Wa、Ishimaru Yoshiro、Misaka Takumi、Oteiza Pablo、Crall James、Edwards Scott V.、Buttemer William、Matsumura Shuichi、Baldwin Maude W.
- Journal Title
  
  Science
  
  Volume: 373 Issue: 6551 Pages: 226-231
- DOI
  10.1126/science.abf6505
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16241, KAKENHI-PUBLICLY-20H04987, KAKENHI-PROJECT-19H02907, KAKENHI-PROJECT-19H02915, KAKENHI-PROJECT-20H02941, KAKENHI-PROJECT-18KK0166
[Journal Article] Ibuprofen, a nonsteroidal anti-inflammatory drug, is a potent inhibitor of the human sweet taste receptor2020
- Author(s)
  Nakagita, T., Taketani, C., Narukawa, M., Hirokawa, T., Kobayashi, T., and Misaka, T.
- Journal Title
  
  Chem. Senses
  
  Volume: 45 Issue: 8 Pages: 667-673
- DOI
  10.1093/chemse/bjaa057
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H02907
[Journal Article] Suppression of hTAS2R16 signaling by umami substances2020
- Author(s)
  Rhyu, M.R., Kim, Y., and Misaka, T.
- Journal Title
  
  Int. J. Mol. Sci.
  
  Volume: 21 Issue: 19 Pages: 7045-7045
- DOI
  10.3390/ijms21197045
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H02907
[Journal Article] Bitter taste receptor activation by hop-derived bitter components induces gastrointestinal hormone production in enteroendocrine cells2020
- Author(s)
  Yamazaki, T., Takahashi, C., Taniguchi, Y., Narukawa, M., Misaka, T., and Ano, Y.
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 533 Issue: 4 Pages: 704-709
- DOI
  10.1016/j.bbrc.2020.10.099
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H02907
[Journal Article] Structural insights into the differences among lactisole derivatives in inhibitory mechanisms against the human sweet taste receptor2019
- Author(s)
  Nakagita T, Ishida A, Matsuya T, Kobayashi T, Narukawa M, Hirokawa T, Hashimoto M, and Misaka T
- Journal Title
  
  PLoS ONE
  
  Volume: 14 Issue: 3 Pages: e0213552-e0213552
- DOI
  10.1371/journal.pone.0213552
- NAID
  120007133042
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H03045, KAKENHI-PROJECT-16H04918, KAKENHI-PROJECT-17K01940
[Journal Article] Food functionality research as a new national project in special reference to improvement of cognitive and locomotive abilities2018
- Author(s)
  Abe Keiko、Misaka Takumi
- Journal Title
  
  Bioscience, Biotechnology, and Biochemistry
  
  Volume: 82 Issue: 4 Pages: 573-583
- DOI
  10.1080/09168451.2017.1412249
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H04918, KAKENHI-PROJECT-18K19728, KAKENHI-PROJECT-17H01962
[Journal Article] Positive/Negative Allosteric Modulation Switching in an Umami Taste Receptor (T1R1/T1R3) by a Natural Flavor Compound, Methional.2018
- Author(s)
  Toda Y, Nakagita T, Hirokawa T, Yamashita Y, Nakajima A, Narukawa M, Ishimaru Y, Uchida R, Misaka T.
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1 Pages: 11796-11796
- DOI
  10.1038/s41598-018-30315-x
- NAID
  120006546000
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K14427, KAKENHI-PROJECT-18KK0166, KAKENHI-PROJECT-16H04918, KAKENHI-PROJECT-16H04919, KAKENHI-PROJECT-18J00315
[Journal Article] Expression of serotonin receptor genes in cranial ganglia.2016
- Author(s)
  Maeda, N., Ohmoto, M., Yamamoto, K., Kurokawa, A., Narukawa, M., Ishimaru, Y., Misaka, T., Matsumoto, I., Abe, K.
- Journal Title
  
  Neurosci Lett
  
  Volume: 617 Pages: 46-51
- DOI
  10.1016/j.neulet.2016.01.050
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26660108, KAKENHI-PROJECT-25292068, KAKENHI-PROJECT-26242007, KAKENHI-PROJECT-15K12334
[Journal Article] Identification of key neoculin residues responsible for the binding and activation of the sweet taste receptor.2015
- Author(s)
  Koizumi, T., Terada, T., Nakajima, K., Kojima, M., Koshiba, S., Matsumura, Y., Kaneda, K., Asakura, T., Shimizu, A., Abe, K., and Misaka, T.
- Journal Title
  
  Scientific Reports
  
  Volume: 5 Issue: 1 Pages: 12947-12947
- DOI
  10.1038/srep12947
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K12334, KAKENHI-PROJECT-26242007, KAKENHI-PROJECT-15H05624
[Journal Article] Expression of the synaptic exocytosis-regulating molecule complexin 2 in taste buds and its participation in peripheral taste transduction2015
- Author(s)
  Kurokawa A, Narukawa M, Ohmoto M, Yoshimoto J, Abe K, Misaka T.
- Journal Title
  
  Journal of Neurochemistry
  
  Volume: 印刷中 Issue: 6 Pages: 806-814
- DOI
  10.1111/jnc.13073
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26712014, KAKENHI-PROJECT-15K12334, KAKENHI-PROJECT-26242007
[Journal Article] Rapid Expansion of Phenylthiocarbamide Non-Tasters among Japanese Macaques.2015
- Author(s)
  Suzuki-Hashido, N., Hayakawa, T., Matsui, A., Go, Y., Ishimaru, Y., Misaka, T., Abe, K., Hirai, H., Satta, Y., and Imai, H.
- Journal Title
  
  PLoS ONE
  
  Volume: 22 Issue: 7 Pages: e0132016-e0132016
- DOI
  10.1371/journal.pone.0132016
- NAID
  120005745670
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K12334, KAKENHI-PUBLICLY-26117512, KAKENHI-PROJECT-15H02421, KAKENHI-PROJECT-26242007, KAKENHI-PROJECT-15H05242, KAKENHI-PROJECT-12J04300, KAKENHI-PROJECT-26640065, KAKENHI-PROJECT-26660108, KAKENHI-PROJECT-24370096, KAKENHI-PROJECT-25292068, KAKENHI-PROJECT-26304008, KAKENHI-PROJECT-25711027
[Journal Article] Nuclear receptor-mediated alleviation of alcoholic fatty liver by polyphenols contained in alcoholic beverages.2014
- Author(s)
  Yao, R., Yasuoka, A., Kamei, A., Ushiama, S., Kitagawa, Y., Rogi, T., Shibata, H., Abe, K., and Misaka, T.
- Journal Title
  
  PLoS ONE
  
  Volume: e87142 Issue: 2 Pages: e87142-e87142
- DOI
  10.1371/journal.pone.0087142
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25560046, KAKENHI-PROJECT-26242007
[Journal Article] Luteolin and Quercetin Affect the Cholesterol Absorption Mediated by Epithelial Cholesterol Transporter Niemann Pick C1-Like 1 in Caco-2 Cells and Rats2014
- Author(s)
  Nekohashi M, Ogawa M, Ogihara T, Nakazawa K, Kato H, Misaka T, Abe K, Kobayashi S
- Journal Title
  
  PLOS One
  
  Volume: 23 Issue: 5 Pages: e97901-e97901
- DOI
  10.1371/journal.pone.0097901
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24500969, KAKENHI-PROJECT-25560046, KAKENHI-PROJECT-26242007
[Journal Article] Two distinct determinants of ligand specificity in T1R1/T1R3 (the umami taste receptor).2013
- Author(s)
  Yasuka Tbda, Tomoya Nakagita, Takashi Hayakawa, Shinji Okada, Masataka Narukawa, Hiroo Imai, Yoshiro Ishimaru, Takumi Misaka.
- Journal Title
  
  The Journal of Biological Chemistry
  
  Volume: 288 Issue: 52 Pages: 36863-36877
- DOI
  10.1074/jbc.m113.494443
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-12J04270, KAKENHI-PROJECT-23688016, KAKENHI-PROJECT-24370096, KAKENHI-PROJECT-24405018, KAKENHI-PROJECT-24658115, KAKENHI-PROJECT-25257409, KAKENHI-PROJECT-25292068
[Journal Article] Amiloride reduces the sweet taste intensity by inhibiting the human sweet taste receptor Biochem.2010
- Author(s)
  Imada, T., Misaka, T., Fujiwara, S., Okada, S., Fukuda, Y., Abe, K.
- Journal Title
  
  Biophys. Res. Commun. (in press)
- Data Source
  KAKENHI-PROJECT-20688015
[Journal Article] pH-Dependent inhibition of the human bitter taste receptor hTAS2R16 by a variety of acidic substances.2009
- Author(s)
  Sakurai, T., Misaka, T., Nagai, T., Ishimaru, Y., Matsuo, S., Asakura, T., Abe, K.
- Journal Title
  
  J. Agric. Food Chem. 57
  
  Pages: 2508-2514
- Data Source
  KAKENHI-PROJECT-20688015
[Journal Article] pH-dependent structural change of neoculin in special reference to its taste-modifying activity.2009
- Author(s)
  Morita, Y., Nakajima, K., Iiduka, K., Terada, T., Shimizu-Ibuka, A., Ito, K., Koizumi, A., Asakura, T., Misaka, T., Abe, K.
- Journal Title
  
  Biosci. Biotechnol. Biochem. 73
  
  Pages: 2552-2555
- Data Source
  KAKENHI-PROJECT-20688015
[Journal Article] Acetic acid activates PKD1L3-PKD2L1 channel-a candidate sour taste receptor.2009
- Author(s)
  Ishii, S., Misaka, T., Kishi, M., Kaga, T., Ishimaru, Y., Abe, K.
- Journal Title
  
  Biochem. Biophys. Res. Commun. 385
  
  Pages: 346-350
- Data Source
  KAKENHI-PROJECT-20688015
[Journal Article] Construction of a taste-blind medaka fish and quantitative assay of its preference-aversion behavior2008
- Author(s)
  Aihara, Y., Yasuoka, A., Iwamoto, S., Yoshida, Y., Misaka, T., Abe, K.
- Journal Title
  
  Gene Brain Behav. 7
  
  Pages: 924-932
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16108004
[Journal Article] Acid-induced sweetness of neoculin is ascribed to its pH-dependent agonistic-antagonistic interaction with human sweet taste receptor2008
- Author(s)
  Nakajima, K., Morita, Y., Koizumi, A., Asakura, T., Terada, T., Ito, K., Shimizu-Ibuka, A., Maruyama, J., Kitamoto, K., Misaka, T., Abe, K.
- Journal Title
  
  FASEB J. 22
  
  Pages: 2323-2330
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16108004
[Journal Article] Advanced method for high-throughput expression of mutated eukaryotic membrane proteins in Saccharomyces cerevisiae2008
- Author(s)
  Ito, K., Sugawara, T., Shiroishi, M., Tokuda, N., Kurokawa, A., Misaka, T., Makyio, H., Yurugi-Kobayashi, T., Shimamura, T., Nomura, N., Murata, T., Abe, K., Iwata, S., Kobayashi.T.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 371
  
  Pages: 841-845
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16108004
[Journal Article] Signal peptide peptidase and its homologues in Arabidopsis thaliana : plant tissue-specific expression and distinct subcellular localization2008
- Author(s)
  Tamura, T., Asakura, T., Uemura, T., Ueda, T., Terauchi, T., Misaka, T., Abe, K.
- Journal Title
  
  FEBS J. 275
  
  Pages: 34-43
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16108004
[Journal Article] Biochemical and Genomic Analysis of Neoculin Compared to Monocot Mannose-Binding Lectins2008
- Author(s)
  Shimizu-Ibuka, A., Nakai, Y., Nakamori, K., Morita, Y., Nakajima, K., Kadota, K., Watanabe, H., Okubo, S., Terada, T., Asakura, T., Misaka, T., Abe, K.
- Journal Title
  
  J.Agric.Food Chem. 56
  
  Pages: 5338-5344
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16108004
[Journal Article] Neoculin, a taste-modifying sweet protein, accumulates in ripening fruits of cultivated Curculigo latifolia2008
- Author(s)
  Okubo, S., Asakura, T., Okubo, K., Abe, K., Misaka, T., Akita, T., Abe, K.
- Journal Title
  
  J.Plant Physiol. 165
  
  Pages: 1964-1969
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16108004
[Journal Article] Aquaporin-11 knockout mice and polycystic kidney disease animals share a common mechanism of cyst formation2008
- Author(s)
  Okada, S., Misaka, T., Tanaka, Y., Matsumoto, I., Ishibashi, K., Sasaki, S., Abe, K.
- Journal Title
  
  FASEB J. 22
  
  Pages: 3672-3684
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16108004
[Journal Article] Taste-modifying sweet protein, neoculin, is received at human T1R3 amino terminal domain2007
- Author(s)
  Koizumi, A., Nakajima, K., Asakura, T., Morita, Y., Ito, K., Shimizu-Ibuka, A., Misaka, T., Abe.K.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 358
  
  Pages: 585-589
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16108004
[Journal Article] Trans-genic labeling of taste receptor cells in model fish under the control of the 5'-upstream region of medaka phospholipase C-beta 2 gene2007
- Author(s)
  Aihara, Y., Yasuoka, A., Yoshida, Y, Ohmoto, M., Shimizu-Ibuka, A., Misaka, T., Furutani-Seiki, M., Matsumoto I., Abe.K.
- Journal Title
  
  Gene Expr.Patterns 7
  
  Pages: 149-157
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16108004
[Journal Article] Taste-modifying sweet protein, neoculin, is received at human T1R3 amino terminal domain2007
- Author(s)
  Koizumi, A., Nakajima, K., Asakura, T., Morita, Y., Ito, K., Shmizu-Ibuka, A., Misaka, T., Abe, K.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 358
  
  Pages: 585-589
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16108004
[Journal Article] Characterization of ligands for fish taste receptors2007
- Author(s)
  Oike, H., Nagai, T., Furuyama, A., Okada, S., Aihara, Y., Ishimaru, Y., Marui, T., Matsumoto, I., Misaka, T., Abe, K.
- Journal Title
  
  J.Neurosci. 27
  
  Pages: 5584-5592
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16108004
[Journal Article] Transgenic labeling of taste receptor cells in model fish under the control of the 5'-upstream region of medaka phospholipase C-beta 2 gene2007
- Author(s)
  Aihara, Y., Yasuoka, A., Yoshida, Y, Ohmoto, M., Shimizu-Ibuka, A., Misaka, T., Furutani-Seiki, M., Matsumoto, I., Abe, K.
- Journal Title
  
  Gene Expr.Patterns 7
  
  Pages: 149-157
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16108004
[Journal Article] Transient receptor potential channel M5 and phospholipaseC-b2 colocalizing in zebrafish taste receptor cells2007
- Author(s)
  Yoshida, Y.Saito, K., Aihara, Y.Okada, S.Misaka, T., Abe.K.
- Journal Title
  
  Neuroreport 18
  
  Pages: 1517-1520
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16108004
[Journal Article] Characterization of Ligands for Fish Taste Receptors2007
- Author(s)
  Oike, H., Nagai, T., Furuyama, A., Okada, S., Aihara, Y., Ishimaru, Y., Marui, T., Misaka, T., Abe.K.
- Journal Title
  
  J.Neurosci. 27
  
  Pages: 5584-5592
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16108004
[Journal Article] Microbial production of sensory-active miraculin2007
- Author(s)
  Ito, K., Asakura, T., Morita, Y., Nakajima, K., Koizumi, A., Shimizu-Ibuka, A., Masuda, K., Ishiguro, M., Terada, T., Maruyama, J., Kitamoto, K., Misaka, T., Abe.K.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 360
  
  Pages: 407-411
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16108004
[Journal Article] Arachidonic acid can function as a signaling modulator by activating the TRPM5 cation channel in taste receptor cells2006
- Author(s)
  Oike, H., Wakamori, M., Mori, Y., Nakanishi, H., Taguchi, R., Misaka, T., Matsumoto, I., Abe K.
- Journal Title
  
  Biochim.Biophys.Acta 1761
  
  Pages: 1078-1084
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16108004
[Journal Article] Crystal structure of neoculin : insights into its sweetness and taste-modifying activity2006
- Author(s)
  Shimizu-Ibuka, A., Morita, Y., Terada, T., Asakura, T., Nakajima, K., Iwata, S., Misaka, T., Sorimachi, H., Arai, S., Abe.K.
- Journal Title
  
  J.Mol.Biol. 359
  
  Pages: 148-158
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16108004
[Journal Article] Arachidonic acid can function as a signaling modulator by activating the TRPM5 cation channel in taste receptor cells2006
- Author(s)
  Oike, H., Wakamori, M., Mori, Y., Nakanishi, H., Taguchi, R, Misaka, T., Matsumoto, I., Abe.K.
- Journal Title
  
  Biochim.Biophys.Acta 1761
  
  Pages: 1078-1084
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16108004
[Journal Article] Taste receptor cells express voltage-dependent potassium channels in a cell age-specific manner2006
- Author(s)
  Ohmoto, M., Matsumoto, I., Misaka, T., Abe.K.
- Journal Title
  
  Chem.Senses 31
  
  Pages: 739-746
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16108004
[Journal Article] Extracellular production of a heterodimetric protein, neoculin, with sweet-tasting and taste-modifying activities by Aspergillus oryzae2006
- Author(s)
  Nakajima, K, Asakura, T., Maruyama, J., Morita, Y., Oike, H., Shimizu-Ibuka, A., Misaka, T., Sorimachi, H., Arai, S., Kitamoto, K, Abe.K.
- Journal Title
  
  Appl.Environ.Microbial. 72
  
  Pages: 3716-3723
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16108004
[Journal Article] Crystal structure of neoculin : insights into its sweetness and taste-modifying activity2006
- Author(s)
  Shimizu-Ibuka, A., Morita, Y., Terada, T., Asakura, T., Nakajima, K., Iwata, S., Misaka, T., Sorimachi, H., Arai, S., Abe, K.
- Journal Title
  
  J.Mol.Biol. 359
  
  Pages: 148-158
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16108004
[Journal Article] Neoculin, a taste-modifying protein, is recognized by human sweet taste receptor2006
- Author(s)
  Nakajima, K., Asakura, T., Oike, H., Morita, Y., Shimizu-Ibuka, A., Misaka, T., Sorimachi, H., Arai, S., Abe.K.
- Journal Title
  
  Neuroreport 17
  
  Pages: 1241-1244
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16108004
[Journal Article] The dynamin-related mouse mitochondrial GTPase OPA1 alters the structure of the mitochondrial inner membrane when exogenously introduced into COS-7 cells.2006
- Author(s)
  Misaka, T.
- Journal Title
  
  Neurosci. Res. 55
  
  Pages: 123-133
- NAID
  10020615716
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16108004
[Journal Article] Taste Receptor Cells Express Voltage- Dependent Potassium Channels in a Cell Age-Specific Manner2006
- Author(s)
  Ohmoto, M., Matsumoto, I., Misaka, T., Abe, K.
- Journal Title
  
  Chem.Senses 31
  
  Pages: 739-746
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16108004
[Journal Article] The dynamin-related mouse mitochondrial GTPase OPA1 alters the structure of the mitochondrial inner membrane when exogenously introduced into COS-7 cells2006
- Author(s)
  Misaka, T, Murate, M., Fujimoto, K., Kubo, Y.
- Journal Title
  
  Neurosci.Res. 55
  
  Pages: 123-133
- NAID
  10020615716
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16108004
[Journal Article] The dynamin-related mouse mitochondrial GTPase OPA1 alters the structure of the mitochondrial inner membrane when exogenously introduced into COS-7 cells2006
- Author(s)
  Misaka T.et al.
- Journal Title
  
  Neurosci.Res. (印刷中)
- NAID
  10020615716
- Data Source
  KAKENHI-PROJECT-16790141
[Journal Article] OPA1 expression in the normal rat retina and optic nerve2005
- Author(s)
  Ju, W.K., Misaka, T., Kushnareva, Y., Nakagomi, S., Agarwal, N., Kubo, Y., Lipton, S.A., Bossy-Wetzel, E.
- Journal Title
  
  J.Comp.Neurol. 488
  
  Pages: 1-10
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16108004
[Patent] 甘味受容体発現コンストラクト、これを発現させた細胞体、及びその利用2009
- Inventor(s)
  阿部啓子、三坂巧、今田隆将、藤原聡
- Industrial Property Rights Holder
  東京大学、長谷川香料株式会社
- Filing Date
  2009-12-02
- Data Source
  KAKENHI-PROJECT-20688015
[Presentation] 甘味受容体阻害剤が示すうま味受容体阻害活性の検討2024
- Author(s)
  川﨑舞子、木寺優太、三坂巧
- Organizer
  日本農芸化学会2024年度大会
- Data Source
  KAKENHI-PROJECT-23K23549
[Presentation] 高甘味度甘味料の後口に感じられる苦味の客観的強度評価法の改良2024
- Author(s)
  齋藤美優、三坂巧
- Organizer
  日本農芸化学会2024年度大会
- Data Source
  KAKENHI-PROJECT-23K23549
[Presentation] 甘味阻害剤前処理によるヒト甘味受容体発現細胞の細胞応答上昇のメカニズム解析2023
- Author(s)
  荻田健太郎、三坂巧
- Organizer
  日本農芸化学会2023年度大会
- Data Source
  KAKENHI-PROJECT-23K23549
[Presentation] L-アミノ酸に高感度で応答する魚類味覚受容体の探索2023
- Author(s)
  郷田竜生、渡邊壮一、三坂巧
- Organizer
  日本農芸化学会2023年度大会
- Data Source
  KAKENHI-PROJECT-23K23549
[Presentation] 塩味受容に関与する新規分子の同定2022
- Author(s)
  成川真隆、笠原洋一、石丸喜朗、三坂巧、阿部啓子、朝倉富子
- Organizer
  日本農芸化学会2022年度大会
- Data Source
  KAKENHI-PROJECT-18KK0166
[Presentation] 味覚受容体を用いた細胞アッセイによる呈味評価とその応用2022
- Author(s)
  三坂巧
- Organizer
  日本農芸化学会2022年度大会
- Data Source
  KAKENHI-PROJECT-19H02907
[Presentation] ヒトT1R1/T1R3の受容体活性を調節する受容体内の構造的特徴2022
- Author(s)
  陳思宇、三坂巧
- Organizer
  日本農芸化学会2022年度大会
- Data Source
  KAKENHI-PROJECT-19H02907
[Presentation] 霊長類における旨味受容体のヌクレオチド感受性と食性の関わり2022
- Author(s)
  戸田安香、早川卓志、糸井川壮大、栗原洋介、中北智哉、Amanda Melin、河村正二、今井啓雄、石丸喜朗、三坂巧
- Organizer
  日本農芸化学会2022年度大会
- Data Source
  KAKENHI-PROJECT-19H02907
[Presentation] 霊長類における旨味受容体のヌクレオチド感受性と食性の関わり2022
- Author(s)
  戸田安香、早川卓志、糸井川壮大、栗原洋介、中北智哉、Amanda Melin、河村正二、今井啓雄、石丸喜朗、三坂巧
- Organizer
  日本農芸化学会2022年度大会
- Data Source
  KAKENHI-PROJECT-18KK0166
[Presentation] ヒト味覚受容体発現細胞を用いた清涼飲料水をモデル溶液とした呈味強度評価法の改良2022
- Author(s)
  山口美波、三坂巧
- Organizer
  日本農芸化学会2022年度大会
- Data Source
  KAKENHI-PROJECT-19H02907
[Presentation] 高い応答性を有する hT1R1/hT1R3安定発現細胞株作出の試み2021
- Author(s)
  木寺優太、竹谷千晶、三坂巧
- Organizer
  日本農芸化学会2021年度大会
- Data Source
  KAKENHI-PROJECT-19H02907
[Presentation] 霊長類におけるグルタミン酸の旨味受容と食物の関わり2021
- Author(s)
  戸田安香、石丸喜朗、三坂巧
- Organizer
  第75回日本人類学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-18KK0166
[Presentation] メチオナール構造類縁体の嗜好味受容体活性調節能の検討2021
- Author(s)
  五十嵐晶帆、鈴木あゆ、三坂巧
- Organizer
  日本農芸化学会2021年度大会
- Data Source
  KAKENHI-PROJECT-19H02907
[Presentation] 霊長類旨味受容体の機能と食性の関わりの解明2021
- Author(s)
  戸田安香、早川卓志、栗原洋介、中北智哉、河村正二、今井啓雄、石丸喜朗、三坂巧
- Organizer
  日本農芸化学会2021年度大会
- Data Source
  KAKENHI-PROJECT-18KK0166
[Presentation] 霊長類におけるグルタミン酸の味受容の進化2020
- Author(s)
  戸田安香、石丸喜朗、三坂巧
- Organizer
  第43回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18KK0166
[Presentation] 甘味受容体T1R3サブユニット膜貫通領域における活性型・不活性型モデルの比較2020
- Author(s)
  中北智哉、成川真隆、広川貴次、三坂巧
- Organizer
  日本農芸化学会2020年度大会（誌上発表のみ）
- Data Source
  KAKENHI-PROJECT-19H02907
[Presentation] おいしさを決定する味物質受容の分子メカニズム2020
- Author(s)
  三坂　巧
- Organizer
  第60回日本臨床化学会年次学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19H02907
[Presentation] レポーターアッセイを用いた客観的甘味評価系の構築2020
- Author(s)
  井手美里、三坂巧
- Organizer
  日本農芸化学会2020年度大会（誌上発表のみ）
- Data Source
  KAKENHI-PROJECT-19H02907
[Presentation] 霊長類旨味受容体における高いグルタミン酸感受性獲得の分子機構2020
- Author(s)
  戸田安香、早川卓志、中北智哉、河村正二、今井啓雄、石丸喜朗、三坂巧
- Organizer
  日本農芸化学会2020年度大会
- Data Source
  KAKENHI-PROJECT-18KK0166
[Presentation] ヒト甘味受容体発現細胞の応答強度向上のための培養条件検討2019
- Author(s)
  竹谷千晶、松谷拓弥、中北智哉、三坂巧
- Organizer
  日本農芸化学会2019年度大会
- Data Source
  KAKENHI-PROJECT-16H04918
[Presentation] 抗炎症剤イブプロフェンの甘味受容体に対する阻害剤としての作用機構解析2019
- Author(s)
  中北智哉、竹谷千晶、成川真隆、小林拓也、三坂巧
- Organizer
  日本農芸化学会2019年度大会
- Data Source
  KAKENHI-PROJECT-16H04918
[Presentation] うま味受容体におけるリガンド選択性を決める分子メカニズム2019
- Author(s)
  三坂　巧
- Organizer
  第61回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-19H02907
[Presentation] 旨味受容体T1R1/T1R3と食性との関わり2019
- Author(s)
  戸田安香、石丸喜朗、三坂　巧
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19H02907
[Presentation] 霊長類T1R1/T1R3におけるグルタミン酸受容能獲得の分子基盤：クモザルに注目した検討2019
- Author(s)
  戸田安香、早川卓志、中北智哉、河村正二、今井啓雄、石丸喜朗、三坂巧
- Organizer
  日本農芸化学会2019年度大会
- Data Source
  KAKENHI-PROJECT-18KK0166
[Presentation] ヒト甘味受容体安定発現細胞を用いた高濃度糖溶液の甘味評価法の改良2019
- Author(s)
  井手美里、竹谷千晶、三坂巧
- Organizer
  日本農芸化学会2019年度大会
- Data Source
  KAKENHI-PROJECT-16H04918
[Presentation] ヒト甘味受容体安定発現細胞株の応答性向上の試み2018
- Author(s)
  竹谷千晶、三坂巧
- Organizer
  日本農芸化学会2018年度大会
- Data Source
  KAKENHI-PROJECT-16H04918
[Presentation] 甘味物質とヒト甘味受容体膜貫通領域の相互作用モデルの検討2017
- Author(s)
  松谷拓弥、中北智哉、広川貴次、三坂巧
- Organizer
  日本農芸化学会2017年度大会
- Place of Presentation
  京都女子大学（京都府京都市）
- Year and Date
  2017-03-17
- Data Source
  KAKENHI-PROJECT-16H04918
[Presentation] プロトン透過性膜タンパク質を利用した細胞外pH低下検出系の開発2016
- Author(s)
  三島誠、三坂巧
- Organizer
  日本農芸化学会2016年度大会
- Place of Presentation
  札幌
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-15K14914
[Presentation] 食品ポリフェノールによる世代を超えての代謝改善に関わるエピジェネティクス修飾2015
- Author(s)
  高須亮佑、ホナーギエクレア、近藤隆、阿部啓子、三坂巧、白髭克彦、安岡顕人、岡田晋治
- Organizer
  日本農芸化学会2015年度大会
- Place of Presentation
  岡山
- Year and Date
  2015-03-28
- Data Source
  KAKENHI-PROJECT-26242007
[Presentation] 味蕾におけるコンプレキシンファミリーの発現と末梢味情報伝達におけるコンプレキシンの関与2015
- Author(s)
  成川真隆、黒川あずさ、應本真、吉本靖東、阿部啓子、三坂巧
- Organizer
  日本農芸化学会2015年度大会
- Place of Presentation
  岡山
- Year and Date
  2015-03-28
- Data Source
  KAKENHI-PROJECT-26242007
[Presentation] フラボノイドがコレステロール腸管吸収トランスポーター発現に与える影響2015
- Author(s)
  成川真隆、黒川あずさ、應本　真、吉本靖東、阿部啓子、三坂　巧
- Organizer
  日本農芸化学会2015年度大会
- Place of Presentation
  岡山
- Year and Date
  2015-03-28
- Data Source
  KAKENHI-PROJECT-26242007
[Presentation] 旨味受容体T1R1/T1R3のL-Glu活性を決定する因子の同定2014
- Author(s)
  戸田安香、中北智哉、岡田晋治、成川真隆、石丸喜朗、三坂巧
- Organizer
  日本農芸化学会
- Place of Presentation
  明治大学（神奈川県）
- Data Source
  KAKENHI-PROJECT-25292068
[Presentation] 表面プラズモン共鳴法を用いたヒト甘味受容体と甘味タンパク質との直接相互作用の検出2011
- Author(s)
  尹滔文、三坂巧
- Organizer
  日本農芸化学会2011年度大会
- Place of Presentation
  京都女子大(京都府)
- Year and Date
  2011-03-26
- Data Source
  KAKENHI-PROJECT-21658046
[Presentation] ヒト甘味受容体発現細胞による甘味阻害剤の検索2010
- Author(s)
  今田隆将、阿部啓子、三坂巧
- Organizer
  日本農芸化学会2010年度大会
- Place of Presentation
  東京
- Year and Date
  2010-03-29
- Data Source
  KAKENHI-PROJECT-20688015
[Presentation] ヒト甘味受容体安定発現細胞株の作製の試み2009
- Author(s)
  今田隆将、阿部啓子、三坂巧
- Organizer
  日本農芸化学会2009年度大会
- Place of Presentation
  福岡
- Year and Date
  2009-03-29
- Data Source
  KAKENHI-PROJECT-20688015
[Presentation] ヒト味覚受容体(hTIRs)細胞外領域の昆虫細胞発現系を用いた発現生産2008
- Author(s)
  三坂巧
- Organizer
  日本農芸化学会2008年度大会
- Place of Presentation
  名古屋
- Year and Date
  2008-03-28
- Data Source
  KAKENHI-PROJECT-16108004

1. ISHIMARU YOSHIRO (10451840)

# of Collaborated Projects: 3 results

# of Collaborated Products: 12 results
2. ABE Keiko (10151094)

# of Collaborated Projects: 2 results

# of Collaborated Products: 29 results
3. NAKAGAWA Keiichi (80188896)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. MATSUMOTO Ichiro (00291328)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
5. YOSHIHIRO Yoshihiko (20220717)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. ASAKURA Tomiko (20259013)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 井深章子 (60301420)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 戸田安香 (10802978)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
9. NARUKAWA Masataka

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
10. 早川卓志

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
11. 小林彰子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 中北智哉

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Misaka Takumi 三坂 巧

MISAKA Takumi 三坂 巧

Research Projects

Research Products

Co-Researchers

新生仔期の呈味刺激による味覚認知回路の質的変化の検出―幼少期の食事は脳を変える？Principal Investigator

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嗜好味受容体におけるリガンド選択性・感受性を決定する因子の構造活性相関による同定Principal Investigator

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Improvement of the taste measurement techniques using taste receptor-expressing cells and characterization of natural compounds contributing to the taste enhancer/suppressorPrincipal Investigator

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Relationship between diversification of eating habits and taste receptor functions using birds as models

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Characterization of chemical compounds contributing to the taste enhancer/suppressor using the taste receptor-expressing cells and examination of those molecular mechanismsPrincipal Investigator

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Construction of a novel fluorescent measurement system to evaluate pH values in fluorescent imaging analysisPrincipal Investigator

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Peripheral Response to Tastant Signals and Central Cognition for Analysis of Their Coordination and its Application to the Science of Food for Life

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Functional analysis of cells expressing taste-related genes in the gastrointestinal tract

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ヒト味覚受容体発現細胞を用いた味の相乗・相殺効果の分子メカニズムの解析Principal Investigator

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味物質の呈味持続性を規定する因子の探索Principal Investigator

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Construction of a novel taste sensor using the taste receptor protein of vertebrate originPrincipal Investigator

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味蕾細胞-味神経細胞間における情報伝達機構の解明を目指した初代共培養系の確立Principal Investigator

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脊椎動物由来味覚受容体の構造機能連関を基盤とした味物質受容機構の体系的解析Principal Investigator

Principal Investigator

Project Period (FY)

Misaka Takumi 三坂巧

MISAKA Takumi 三坂巧