YAMAUCHI Mika 山内美香

Researcher Number	40379681
Affiliation (based on the past Project Information) *help	2012 – 2013: 島根大学, 医学部, 講師 2010 – 2011: 島根大学, 医学部, 助教 2007: Shimane University, Department of Medicine, Assistant Professor 2006: 島根大学, 医学部, 助手
Review Section/Research Field	Principal Investigator General internal medicine (including Psychosomatic medicine) Except Principal Investigator Endocrinology / General internal medicine (including Psychosomatic medicine)
Keywords	Principal Investigator 島根県 / 日本 / osteoporosis / 脂質異常症 / LDLコレステロール / 脂質 / 骨粗鬆症 Except Principal Investigator Wnt / ストロンチウム / Smad3 … More / 副甲状腺ホルモン / 骨芽細胞 / 骨形成 / Smart / Bone formation / Osteoblast / strontium / Stalin / Bisohosohonate / Parathyroid hormone / アポトーシス / TGFβ / グルココルチコイド / Lunt / Smad / smad / スタチン / ビスフォスフォネート / MAPキナーゼ / カルシウム感知受容体 / βカテニン / 終末糖化産物 / 筋芽細胞 / 小胞体ストレス / Tmem119 / 骨形成因子 / 骨粗鬆症 / 老年医学 Less

Examination of relationships between serum levels of LDL cholesterol and bone metabolism-related indices as well as bone fracturePrincipal Investigator
- Principal Investigator
  
  YAMAUCHI Mika
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General internal medicine (including Psychosomatic medicine)
- Research Institution
  Shimane University
Elucidation of bone formation signal aimed at the development of medical treatment of osteoporosis induced by deterioration of bone formation
- Principal Investigator
  
  SUGIMOTO Toshitsugu
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General internal medicine (including Psychosomatic medicine)
- Research Institution
  Shimane University
Research for the elucidation of bone formation signals applied to the development of bone-forming agents
- Principal Investigator
  
  SUGIMOTO Toshitsugu
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Endocrinology
- Research Institution
  Shimane University

All 2014 2013 2012 2011 2010 2007 2006 Other

All Journal Article Presentation Book

[Book] ファーマナビゲーター　SERM編2013
- Author(s)
  山内美香、杉本利嗣
- Total Pages
  355
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-23590882
[Book] 骨粗鬆症の予防と治療ガイドライン2011年版2011
- Author(s)
  山内美香、杉本利嗣
- Total Pages
  167
- Publisher
  ライフサイエンス出版
- Data Source
  KAKENHI-PROJECT-23590882
[Book] 骨粗鬆症の予防と治療ガイドライン 2011年版2011
- Author(s)
  山内美香, 杉本利嗣
- Total Pages
  167
- Publisher
  ライフサイエンス出版
- Data Source
  KAKENHI-PROJECT-23590882
[Journal Article] Increased low-density lipoprotein cholesterol level is associated with non-vertebral fractures in postmenopausal women2014
- Author(s)
  Mika Yamauchi, Toru Yamaguch, Kiyoko Nawata, Ken-ichiro Tanaka, Shin Takaoka, Toshitsugu Sugimoto
- Journal Title
  
  Endocrine
  
  Volume: in press Issue: 1 Pages: 279-286
- DOI
  10.1007/s12020-014-0292-0
- NAID
  120005982748
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590882
[Journal Article] Increased low-density lipoprotein cholesterol level is associated with non-vertebral fractures in postmenopausal women2014
- Author(s)
  Mika Yamauchi, Toru Yamaguchi, Kiyoko Nawata, Ken-ichiro Tanaka, Shin Takaoka, Toshitsugu Sugimoto
- Journal Title
  
  Endocrine
  
  Volume: (Epub ahead of print)
- NAID
  120005982748
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590882
[Journal Article] 生活習慣病が骨へ与える影響2013
- Author(s)
  山内美香、杉本利嗣
- Journal Title
  
  実験治療
  
  Volume: 709巻 Pages: 3-8
- Data Source
  KAKENHI-PROJECT-23590882
[Journal Article] . Fracture risk is increased by the complication of hypertension and treatment with calcium channel blockers in postmenopausal women with type 2 diabetes2013
- Author(s)
  Takaoka S, Yamaguchi T, Tanaka K, Morita M, Yamamoto M, Yamauchi M, Yano S, Sugimoto T
- Journal Title
  
  J Bone Miner Metab
  
  Volume: 31 Issue: 1 Pages: 102-107
- DOI
  10.1007/s00774-012-0389-6
- NAID
  10031168843
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590882, KAKENHI-PROJECT-25460900
[Journal Article] Fracture risk is increased by the complication of hypertension and treatment with calcium channel blockers in postmenopausal women with type 2 diabetes2013
- Author(s)
  Takaoka S, Yamaguchi T, Tanaka K, Morita M, Yamamoto M, Yamauchi M, Yano S, Sugimoto T
- Journal Title
  
  J Bone Miner Metab
  
  Volume: 31巻 Pages: 102-107
- NAID
  10031168843
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590882
[Journal Article] Association of n-3 polyunsaturated fatty acid intake with bone mineral density in postmenopausal women.2013
- Author(s)
  Nawata K, Yamauchi M, Takaoka S, Yamaguchi T, Sugimoto T.
- Journal Title
  
  Calcif Tissue Int
  
  Volume: 未定
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590882
[Journal Article] 骨粗鬆症の最新の知見:生活習慣病2013
- Author(s)
  山内美香
- Journal Title
  
  日本臨牀
  
  Volume: 71 Pages: 451-456
- Data Source
  KAKENHI-PROJECT-23590882
[Journal Article] 骨粗鬆症の最新の知見;生活習慣病2013
- Author(s)
  山内美香
- Journal Title
  
  日本臨牀
  
  Volume: 71巻 Pages: 451-456
- Data Source
  KAKENHI-PROJECT-23590882
[Journal Article] Association of n-3 polyunsaturated fatty acid intake with bone mineral density in postmenopausal women2013
- Author(s)
  Nawata K, Yamauchi M, Takaoka S, Yamaguchi T, Sugimoto T
- Journal Title
  
  Calcif Tissue Int
  
  Volume: 93巻 Pages: 147-54
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590882
[Journal Article] Decreased PTH levels accompanied by low bone formation is associated with vertebral fractures in postmenopausal women with type 2 diabetes2012
- Author(s)
  Yamamoto M, Yamaguchi T, Nawata K, Yamauchi M, Sugimoto T
- Journal Title
  
  J Clin Endocrinol Metab
  
  Volume: 97巻 Pages: 1277-1284
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590882
[Journal Article] 閉経後女性における高LDL血症の骨脆弱性に及ぼす影響2012
- Author(s)
  山内美香、山口徹、名和田清子、高岡伸、杉本利嗣
- Journal Title
  
  Osteoporosis Japan
  
  Volume: 20巻 Pages: 257-260
- Data Source
  KAKENHI-PROJECT-23590882
[Journal Article] Decreased PTH levels accompanied by low bone formation is associated with vertebral fractures in postmenopausal women with type 2 diabetes2012
- Author(s)
  Yamamoto M, Yamaguchi T, Nawata K, Yamauchi M, Sugimoto T
- Journal Title
  
  J Clin Endocrinol Metab
  
  Volume: 97 Pages: 1277-1284
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590656
[Journal Article] The calcium-sensing receptor (CaR) is involved in strontium ranelate-induced osteoblast differentiation and mineralization.2010
- Author(s)
  Takaoka S, Yamaguchi T, Yano S, Yamauchi M, Sugimoto T
- Journal Title
  
  Horm Metab Res
  
  Volume: 42 Pages: 627-631
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590656
[Journal Article] Fasudil hydrochrolide induces osteoblastic differentiation of stromal cell lines, C3H10T1/2 and ST2, via bone morphogenetic protein-2 expression2010
- Author(s)
  Kanazawa I, Yamaguchi T, Yano S, Yamauchi M, Sugimoto T
- Journal Title
  
  Endocr J
  
  Volume: 57(5) Pages: 415-421
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590656
[Journal Article] The combination of high glucose and advanced glycation end-products (AGEs) unhibit the mineralization of osteoblastic MC3T3-E1 cells through glucose-induced increase in the receptor for AGEs2007
- Author(s)
  Ogawa, N., Yamaguchi, N., Yano, S., Yamauchi, M., Yamamoto, M., Sugimoto, T
- Journal Title
  
  Horm Metab Res 39
  
  Pages: 871-875
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591025
[Journal Article] Adiponectin and AMP kinase activator stimulates proliferation, differtentiation and mineralization of osteonlastic MC3T3-E1 cells
- Author(s)
  Kanazawa, I., Yamaguchi, T., Yano, S., Yamauchi, M., Yamamoto, M., Sugimolto, T
- Journal Title
  
  BMC Cell Biol (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591025
[Presentation] Increased low-density lipoprotein cholesterol level is associated with non-vertebral fractures in postmenopausal women2014
- Author(s)
  Yamauchi M、Yamaguchi T、Nawata K、Takaoka S、Sugimoto T
- Organizer
  World Congress on Osteoporosis - International Osteoporosis Foundation - The European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis
- Place of Presentation
  Seville
- Data Source
  KAKENHI-PROJECT-23590882
[Presentation] Increased low-density lipoprotein cholesterol level is associated with non-vertebral fractures in postmenopausal women2014
- Author(s)
  Mika Yamauchi, Toru Yamaguch, Kiyoko Nawata, Ken-ichiro Tanaka, Shin Takaoka, Toshitsugu Sugimoto
- Organizer
  World Congress on Osteoporosis - International Osteoporosis Foundation - The European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis.
- Place of Presentation
  Seville
- Data Source
  KAKENHI-PROJECT-23590882
[Presentation] 高LDLコレステロール血症の非椎体骨脆弱性に及ぼす影響閉経後女性における検討2012
- Author(s)
  山内美香、山口徹、名和田清子、高岡伸、杉本利嗣
- Organizer
  第30回日本骨代謝学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23590882
[Presentation] 閉経後女性における運動機能検査と既存椎体骨折の関連についての検討2012
- Author(s)
  名和田清子、山内美香、田中賢一郎、高岡伸、杉本利嗣
- Organizer
  第14回日本骨粗鬆症学会学術集会
- Place of Presentation
  新潟
- Data Source
  KAKENHI-PROJECT-23590882
[Presentation] 高LDLコレステロール血症の非椎体骨脆弱性に及ぼす影響　閉経後女性における検討2012
- Author(s)
  山内美香, 山口徹, 名和田清子, 高岡伸, 杉本利嗣
- Organizer
  第30回日本骨代謝学会学術集会
- Place of Presentation
  京王プラザホテル（東京）
- Data Source
  KAKENHI-PROJECT-23590882
[Presentation] Relationship between motor function tests and existing vertebral fractures in postmenopausal women2012
- Author(s)
  Kiyoko Nawata, Mika Yamauchi, Ken Tanaka, Shin Takaoka, Toshitsugu Sugimoto
- Organizer
  International Osteoporosis Foundation Regionals - 3rd Asia-Pacific Osteoporosis Meeting
- Place of Presentation
  Kuala Lumpur, Malaysia
- Data Source
  KAKENHI-PROJECT-23590882
[Presentation] 閉経後女性における運動機能検査と既存椎体骨折の関連についての検討2012
- Author(s)
  名和田清子, 山内美香, 田中賢一郎, 高岡伸, 杉本利嗣
- Organizer
  第14回日本骨粗鬆症学会学術集会
- Place of Presentation
  朱鷺メッセ（新潟市）
- Data Source
  KAKENHI-PROJECT-23590882
[Presentation] Relationship between motor function tests and existing vertebral fractures in postmenopausal women2012
- Author(s)
  Nawata K, Yamauchi M, Tanaka K, Takaoka S, Sugimoto T
- Organizer
  International Osteoporosis Foundation Regionals - 3rd Asia-Pacific Osteoporosis Meeting
- Place of Presentation
  Kuala Lumpur
- Data Source
  KAKENHI-PROJECT-23590882
[Presentation] Functional hypoparathyroidism is a risk factor for bone fragility of postmenopausal women with vitamin D insufficiency2012
- Author(s)
  Yamauchi M, Nawata K, Kaji H, Takaoka S, Yamaguchi T, Sugimoto T.
- Organizer
  15th International and 14th European Congress of Endocrinology
- Place of Presentation
  Florence, Italy
- Data Source
  KAKENHI-PROJECT-23590882
[Presentation] Functional hypoparathyroidism is a risk factor for bone fragility of postmenopausal women with vitamin D insufficiency2012
- Author(s)
  Yamauchi M、Nawata K、Kaji H、Takaoka S、Yamaguchi T、Sugimoto T
- Organizer
  15th International and 14th European Congress of Endocrinology
- Place of Presentation
  Florence
- Data Source
  KAKENHI-PROJECT-23590882
[Presentation] 閉経後女性における高LDL血症の骨脆弱性に及ぼす影響2011
- Author(s)
  山内美香,山口徹,名和田清子,高岡伸,杉本利嗣
- Organizer
  第13回日本骨粗鬆症学会
- Place of Presentation
  神戸
- Year and Date
  2011-11-03
- Data Source
  KAKENHI-PROJECT-23590882
[Presentation] 骨粗鬆症診療 update2011
- Author(s)
  山内美香
- Organizer
  第２９回日本骨代謝学会学術集会(招待講演)
- Place of Presentation
  大阪国際会議場（大阪府）
- Data Source
  KAKENHI-PROJECT-23590882
[Presentation] 閉経後女性における高LDL血症の骨脆弱性に及ぼす影響2011
- Author(s)
  山内美香, 山口徹, 名和田清子, 高岡伸, 杉本利嗣
- Organizer
  第１３回日本骨粗鬆症学会
- Place of Presentation
  神戸国際会議場（兵庫県）
- Data Source
  KAKENHI-PROJECT-23590882
[Presentation] 骨粗鬆症診療update2011
- Author(s)
  山内美香
- Organizer
  第29回日本骨代謝学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2011-07-28
- Invited
- Data Source
  KAKENHI-PROJECT-23590882
[Presentation] Glucocorticoid suppresses the differentiation of osteoblasts by enhancing the expression of BMP antagonists, follistatin and danm and pretreatment with alendronate and PTH abolish this process2007
- Author(s)
  Hayashi, K., Yamaguchi, T., Yano, S., Yamauchi, M., Yamamoito, M., The, Sugimoto, T
- Organizer
  The American Society for Bone Mineral Research
- Place of Presentation
  Hawaii USA
- Year and Date
  2007-09-29
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591025
[Presentation] AMP kinase activator (AICAR) and Rho-kinasse inhibitor (hydroxyfasudil) induce the differentiation and mineralization of osteoblastic MC3T3-E1 cells via inhibiting the mavalonate pathway and enhancing BMP-2 expression2007
- Author(s)
  Kanazawa, I., Yamaguchi, T., Yano, S., yamauchi, M., Yamamoto, M., Sugimoto, T
- Organizer
  The American Society for Bone Mineral Research
- Place of Presentation
  Hawaii USA
- Year and Date
  2007-09-29
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591025
[Presentation] Adiponectin stimulates the proliferation, differentiation and mineralization of osteoblastic MC3T3-E1 cells via the adiponectin receptor typel and AMMP signaling pathway2006
- Author(s)
  Kanazawa, I., Yamaguchi, T., Yano, S., Yamauchi, M., Yamamoto, M., Sugimoto, T
- Organizer
  3rd International Osteoporosis Foundation Asia-Pacific Regional Conference onn Osteoporosis & 16th Annual Meeting of the Australian and New Zealand Bone and Mineral Society
- Place of Presentation
  Port Douglas, Australia
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591025

1. SUGIMOTO Toshitsugu (00226458)

# of Collaborated Projects: 3 results

# of Collaborated Products: 31 results
2. YAMAGUCHI Toru (00239899)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
3. YANO Shozo (80403450)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results

YAMAUCHI Mika 山内 美香

Research Projects

Research Products

Co-Researchers

Examination of relationships between serum levels of LDL cholesterol and bone metabolism-related indices as well as bone fracturePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elucidation of bone formation signal aimed at the development of medical treatment of osteoporosis induced by deterioration of bone formation

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Research for the elucidation of bone formation signals applied to the development of bone-forming agents

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] ファーマナビゲーター SERM編2013

Author(s)

Total Pages

Publisher

Data Source

[Book] 骨粗鬆症の予防と治療ガイドライン2011年版2011

Author(s)

Total Pages

Publisher

Data Source

[Book] 骨粗鬆症の予防と治療ガイドライン 2011年版2011

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Increased low-density lipoprotein cholesterol level is associated with non-vertebral fractures in postmenopausal women2014

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Increased low-density lipoprotein cholesterol level is associated with non-vertebral fractures in postmenopausal women2014

Author(s)

Journal Title

NAID

Data Source

[Journal Article] 生活習慣病が骨へ与える影響2013

Author(s)

Journal Title

Data Source

[Journal Article] . Fracture risk is increased by the complication of hypertension and treatment with calcium channel blockers in postmenopausal women with type 2 diabetes2013

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Fracture risk is increased by the complication of hypertension and treatment with calcium channel blockers in postmenopausal women with type 2 diabetes2013

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Association of n-3 polyunsaturated fatty acid intake with bone mineral density in postmenopausal women.2013

Author(s)

Journal Title

Data Source

[Journal Article] 骨粗鬆症の最新の知見:生活習慣病2013

Author(s)

Journal Title

Data Source

[Journal Article] 骨粗鬆症の最新の知見;生活習慣病2013

Author(s)

Journal Title

Data Source

[Journal Article] Association of n-3 polyunsaturated fatty acid intake with bone mineral density in postmenopausal women2013

Author(s)

Journal Title

Data Source

[Journal Article] Decreased PTH levels accompanied by low bone formation is associated with vertebral fractures in postmenopausal women with type 2 diabetes2012

YAMAUCHI Mika 山内美香

[Book] ファーマナビゲーター　SERM編2013

[Presentation] 高LDLコレステロール血症の非椎体骨脆弱性に及ぼす影響　閉経後女性における検討2012