Nagata Daisuke 長田太助

… Alternative Names

NAGATA Daisuke 長田太助

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Researcher Number	40393194
Other IDs
External Links
Affiliation (Current)	2025: 自治医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2019 – 2021: 自治医科大学, 医学部, 教授 2013 – 2016: 自治医科大学, 医学部, 教授 2012: 東京大学, 医学部附属病院, 特任准教授 2011 – 2012: 獨協医科大学, 医学部, 准教授 2010: 東京大学, 医学部附属病院, 特任准教授 … More 2008: The University of Tokyo, 医学部・附属病院, 特任准教授 2008: The University of Tokyo, 医学部附属病院, 特任准教授 2007: The University of Tokyo, 医学部・附属病院, 寄付講座教員 2006: 東京大学, 医学部附属病院, 助手 2005: 京都医療センター, 臨床研究センター, 室長 2005: 独立行政法人国立病院機構(京都医療センター臨床研究センター), 内分泌研究部, 生体統御研究室長 2005: Kyoto Medical Center, Clinical Research Institute of Endocrine and Metabolic Disease, Division Chief, 臨床研究センター・内分泌研究部, 室長 2004: 独立行政法人国立病院機構京都医療センター臨床研究センター, 生体統御研究室, 室長 Less
Review Section/Research Field	Principal Investigator Circulatory organs internal medicine / Basic Section 53040:Nephrology-related / Kidney internal medicine Except Principal Investigator Circulatory organs internal medicine / Endocrinology
Keywords	Principal Investigator 腎尿細管 / 腎間質線維化 / AMPキナーゼ / 血管内皮細胞 / Keap1 / Nrf2 / 傍糸球体毛細血管 / Bardoxolone methyl / Nrf2-KEAP1 / 片側尿細管結紮モデル … More / Nrf2活性化 / バルドキソロンメチル / KEAP1-Nrf2系 / 間質線維化 / 遺伝子改変マウス / オートファジー / アポトーシス / AMPK / 動脈硬化 / 血管 / 一酸化窒素 / ミネラロコルチコイド / アルドステロン / 血管内皮 / 血管病態学 / シグナル伝達 / Akt / PKB / 循環器・高血圧 / AMP kinase / 低酸素 / 分子血管病態学 / apoptosis / 低(無)酸素 … More Except Principal Investigator Osteopontin / Endothelin / Brain natriuretic peptide / Collagen / Cardiac remodeling / Urocortin / Urotensin / オステオポンチン / エンドセリン / 脳性ナトリウム利尿ペプチド / コラーゲン / 心臓リモデリング / ウロコルチン / ウロテンシン / 生理活性 / 循環器・高血圧 / 細胞・組織 / 遺伝子 / 移植・再生医療 / 分子血管病態学 / 血管新生 / 動脈硬化 / キナーゼ / AMP Less

Exploration of the role of Keap1-Nrf2 signaling pathway in renal fibrosisPrincipal Investigator
- Principal Investigator
  
  Nagata Daisuke
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Jichi Medical University
Analysis of AMPK for cell protective function in renal tubular epithelial cellsPrincipal Investigator
- Principal Investigator
  
  Nagata Daisuke
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Jichi Medical University
Development of novel therapy for atherosclerosis using adipose tissue-derived stem cells
- Principal Investigator
  
  HIRATA Yasunobu
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  The University of Tokyo
The mechanism of inhibitory effect of AMP kinase for aldosterone-induced vascular damagePrincipal Investigator
- Principal Investigator
  
  NAGATA Daisuke
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Dokkyo Medical University
  The University of Tokyo
Molecular Mechanism of anti-atherosclerotic function of AMP kinasePrincipal Investigator
- Principal Investigator
  
  NAGATA Daisuke
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  The University of Tokyo
AMP活性化タンパクキナーゼの抗動脈硬化作用と血管新生作用の検討
- Principal Investigator
  
  HIRATA Yasunobu
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  The University of Tokyo
Pathophysiological significance of urotensin/urocortin family
- Principal Investigator
  
  NARUSE Mitsuhide
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Endocrinology
- Research Institution
  Kyoto Medical Center

All 2016 2014 2013 2011 2010 2009 2008 2007 2006 Other

All Journal Article Presentation Book

[Book] 内科【慢性腎臓病(CKD)診療を極める】2016
- Author(s)
  長田太助, 瀧史香, 前嶋明人, 田中哲洋
- Total Pages
  169
- Publisher
  南江堂
- Data Source
  KAKENHI-PROJECT-25461227
[Book] 循環plus【動脈硬化と臓器障害】高齢者CKDの特徴と管理2016
- Author(s)
  長田太助
- Total Pages
  6
- Publisher
  メディカルトリビューン
- Data Source
  KAKENHI-PROJECT-25461227
[Journal Article] Telmisartan activates endothelial nitric oxide synthase via Ser1177 phosphorylation in vascular endothelial cells2014
- Author(s)
  Myojo M, Nagata D, Fujita D, Sato T, Kiyosue A, Takahashi M, Satonaka H, Morishita Y, Nagai R, Komuro I, Hirata Y
- Journal Title
  
  PLOS ONE
  
  Volume: 1 Pages: 1-10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461227
[Journal Article] Aldosterone-induced osteopontin gene transcription in vascular smooth muscle cells involves glucocorticoid response element.2011
- Author(s)
  Kiyosue A, Nagata D, Myojo M, Sato T, Takahashi M, Satonaka H, Nagai R, Hirata Y.
- Journal Title
  
  Hypertens Res.
  
  Volume: 34 Pages: 1283-7
- NAID
  10030277914
- Data Source
  KAKENHI-PROJECT-22590822
[Journal Article] Augmented angiogenesis in adventitia promotes growth of atherosclerotic plaque in apolipoprotein E-deficient mice.2011
- Author(s)
  Tanaka K, Nagata D, Hirata Y, Tabata Y, Nagai R, Sata M
- Journal Title
  
  Atherosclerosis
  
  Volume: 215 Pages: 366-73
- Data Source
  KAKENHI-PROJECT-22590822
[Journal Article] Diagnosis and treatment of endothelial dysfunction in cardiovascular disease.2010
- Author(s)
  Hirata Y, Nagata D, Suzuki E, Nishimatsu H, Suzuki J, Nagai R
- Journal Title
  
  Int Heart J
  
  Volume: 51 Pages: 1-6
- Data Source
  KAKENHI-PROJECT-22590822
[Journal Article] The role of AMP-activated protein kinase in the cardiovascular system.2010
- Author(s)
  Nagata D, Hirata Y
- Journal Title
  
  Hypertens Res
  
  Volume: 33 Pages: 22-28
- NAID
  10026125526
- Data Source
  KAKENHI-PROJECT-22590822
[Journal Article] A new constitutively active mutant ofAMP-activated protein kinase inhibitsanoxia-induced apoptosis of vascularendothelial cell2009
- Author(s)
  Daisuke Nagata, Yasunobu Hirata
- Journal Title
  
  Hypertension Research 32
  
  Pages: 133-139
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590855
[Journal Article] A new constitutively active mutant of AMP-activated protein kinase inhibits anoxia-induced apoptosis of vascular endothelial cell2009
- Author(s)
  Daisuke Nagata, Yasunobu Hira
- Journal Title
  
  Hypertension Research 32
  
  Pages: 133-139
- NAID
  10024829693
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590855
[Journal Article] アルドステロンによる催炎症作用と血管障害作用2008
- Author(s)
  長田太助、平田恭信
- Journal Title
  
  Mebio 25
  
  Pages: 44-53
- Data Source
  KAKENHI-PROJECT-19590855
[Journal Article] アルドステロンによる心血管系臓器障害のメカニズム2007
- Author(s)
  長田太助、平田恭信
- Journal Title
  
  薬学雑誌 127
  
  Pages: 1339-1346
- NAID
  110006380719
- Data Source
  KAKENHI-PROJECT-19590855
[Journal Article] Molecular mechanism of the inhibitory effect of aldosterone on endothelial NO synthase activity2006
- Author(s)
  Nagata D, Hirata Y et al.
- Journal Title
  
  Hypertension 48・1
  
  Pages: 165-171
- Data Source
  KAKENHI-PROJECT-17659229
[Presentation] Investigation of the vascular protective function of AMPK in in vivo models using endothelium- specific AMPK mutant transgenic mice.2013
- Author(s)
  Nagata D, Ishimitsu1 T, Myojo M, Hirata Y
- Organizer
  第77回日本循環器学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22590822
[Presentation] Investigation of the Vascular Protective Function of AMPK in in vivo Models Using Endotheliumspecific AMPK Mutant Transgenic Mice2013
- Author(s)
  長田太助
- Organizer
  第77回日本循環器学会学術集会
- Place of Presentation
  東京都
- Year and Date
  2013-03-15
- Data Source
  KAKENHI-PROJECT-22590823
[Presentation] AMP キナーゼの血管保護作用の研究 -血管内皮特異的 AMPK mutant transgenic mice を用いた in vivo での検討2013
- Author(s)
  長田太助
- Organizer
  第86回日本内分泌学会学術総会
- Place of Presentation
  仙台市
- Year and Date
  2013-04-12
- Data Source
  KAKENHI-PROJECT-22590823
[Presentation] Investigation of the Vascular Protective Function of AMPK in in vivo Models Using Endothelium-specific AMPK Mutant Transgenic Mice2013
- Author(s)
  Daisuke Nagata
- Organizer
  第77回日本循環器学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22590822
[Presentation] Epithelial-Mesenchymal Transitionの抑制機序-AMPキナーゼを介した機序に関する検討2010
- Author(s)
  長田太助
- Organizer
  第58回日本心臓病学会
- Place of Presentation
  東京
- Year and Date
  2010-09-17
- Data Source
  KAKENHI-PROJECT-22590822
[Presentation] アンジオテンシンII受容体拮抗薬によるNO産生機序に関する検討2010
- Author(s)
  長田太助
- Organizer
  第40回日本腎臓学会東部学術大会
- Place of Presentation
  宇都宮市
- Year and Date
  2010-09-25
- Data Source
  KAKENHI-PROJECT-22590823
[Presentation] AMP-activated protein kinase(AMPK) Inhibits Anoxia-Induced Apoptosis of Vascular Endothelial Cell via Akt Activation2008
- Author(s)
  Nagata D, Hirata Y
- Organizer
  The 62nd High Blood Pressure Research Conference 2008
- Place of Presentation
  アトランタ市米国
- Year and Date
  2008-09-17
- Data Source
  KAKENHI-PROJECT-19590855
[Presentation] AMP-activated protein kinase(AMPK)Inhibits Anoxia-induced Apoptosis ofVascular Endothelial Cell via Akt Activation2008
- Author(s)
  Nagata D
- Organizer
  The 62nd High Blood Pressure Research Conference 2008
- Place of Presentation
  Atlanta, GA, USA
- Year and Date
  2008-09-17
- Data Source
  KAKENHI-PROJECT-19590855
[Presentation] AMP キナーゼによる無酸素誘導性血管内皮細胞アポトーシス抑制作用の分子機序の検討2008
- Author(s)
  長田太助
- Organizer
  第31日本高血圧学会学術総会
- Place of Presentation
  札幌
- Year and Date
  2008-10-10
- Data Source
  KAKENHI-PROJECT-19590855
[Presentation] AMP-activated protein kinase による低酸素誘導性血管内皮細胞アポトーシスの抑制機序の検討2008
- Author(s)
  長田太助
- Organizer
  第8回NO学会学術総会
- Place of Presentation
  仙台
- Year and Date
  2008-05-09
- Data Source
  KAKENHI-PROJECT-19590855
[Presentation] NF-kBを介したアルドステロンによる血管障害の分子機序に関する検討2007
- Author(s)
  長田太助、平田恭信
- Organizer
  第30回日本高血圧学会学術総会
- Place of Presentation
  沖縄
- Year and Date
  2007-10-26
- Data Source
  KAKENHI-PROJECT-19590855
[Presentation] 血管内皮細胞におけるアルドステロンのNF-kB活性化機序に関する検討2007
- Author(s)
  長田太助、平田恭信
- Organizer
  第80回日本内分泌学会学術総会
- Place of Presentation
  東京
- Year and Date
  2007-06-14
- Data Source
  KAKENHI-PROJECT-19590855
[Presentation] アルドステロンによる内皮障害のトリガーとしてのNF-kB活性化2007
- Author(s)
  長田太助・平田恭信
- Organizer
  第7回NO学会学術総会
- Place of Presentation
  大津
- Year and Date
  2007-05-17
- Data Source
  KAKENHI-PROJECT-19590855
[Presentation] アルドステロンによる血管内皮障害の分子機序NF-kBを介した系に関する検討2007
- Author(s)
  長田太助、平田恭信
- Organizer
  第11回日本心血管内分泌代謝学会
- Place of Presentation
  東京
- Year and Date
  2007-11-16
- Data Source
  KAKENHI-PROJECT-19590855
[Presentation] AMP-activated protein kinase による無酸素誘導性血管内皮細胞アポトーシス抑制作用機序2007
- Author(s)
  長田太助
- Organizer
  第12日本心血管内分泌代謝学会
- Place of Presentation
  東京
- Year and Date
  2007-11-29
- Data Source
  KAKENHI-PROJECT-19590855
[Presentation] Investigation of the Vascular Protective Function of AMPK in in vivo Models Using Endothelium-specific AMPK Mutant Transgenic Mice
- Author(s)
  長田太助
- Organizer
  第77回日本循環器学会学術集会
- Place of Presentation
  東京都
- Data Source
  KAKENHI-PROJECT-22590823
[Presentation] AMPキナーゼの血管保護作用の研究 -血管内皮特異的AMPK mutant transgenic miceを用いたin vivoでの検討
- Author(s)
  長田太助
- Organizer
  第86回日本内分泌学会学術総会
- Place of Presentation
  仙台市
- Data Source
  KAKENHI-PROJECT-22590823

1. HIRATA Yasunobu (70167609)

# of Collaborated Projects: 4 results

# of Collaborated Products: 22 results
2. TANAKA Kimie (30508065)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
3. NISHIMATSU Hiroaki (60251295)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. TAKAHASHI Masao (00447418)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. NARUSE Mitsuhide (40120018)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. IMAKI Toshihiro (50183190)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. TANABE Akiyo (00236655)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 鈴木越 (40313134)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 佐田政隆 (80345214)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 前嶋明人 (70431707)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Nagata Daisuke 長田 太助

NAGATA Daisuke 長田 太助

Research Projects

Research Products

Co-Researchers

Exploration of the role of Keap1-Nrf2 signaling pathway in renal fibrosisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of AMPK for cell protective function in renal tubular epithelial cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of novel therapy for atherosclerosis using adipose tissue-derived stem cells

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The mechanism of inhibitory effect of AMP kinase for aldosterone-induced vascular damagePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular Mechanism of anti-atherosclerotic function of AMP kinasePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

AMP活性化タンパクキナーゼの抗動脈硬化作用と血管新生作用の検討

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Pathophysiological significance of urotensin/urocortin family

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 内科【慢性腎臓病(CKD)診療を極める】2016

Author(s)

Total Pages

Publisher

Data Source

[Book] 循環plus【動脈硬化と臓器障害】 高齢者CKDの特徴と管理2016

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Telmisartan activates endothelial nitric oxide synthase via Ser1177 phosphorylation in vascular endothelial cells2014

Author(s)

Journal Title

Data Source

[Journal Article] Aldosterone-induced osteopontin gene transcription in vascular smooth muscle cells involves glucocorticoid response element.2011

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Augmented angiogenesis in adventitia promotes growth of atherosclerotic plaque in apolipoprotein E-deficient mice.2011

Author(s)

Journal Title

Data Source

[Journal Article] Diagnosis and treatment of endothelial dysfunction in cardiovascular disease.2010

Author(s)

Journal Title

Data Source

[Journal Article] The role of AMP-activated protein kinase in the cardiovascular system.2010

Author(s)

Journal Title

NAID

Data Source

[Journal Article] A new constitutively active mutant ofAMP-activated protein kinase inhibitsanoxia-induced apoptosis of vascularendothelial cell2009

Nagata Daisuke 長田太助

NAGATA Daisuke 長田太助

[Book] 循環plus【動脈硬化と臓器障害】高齢者CKDの特徴と管理2016