Ishimoto Tetsuya 石本哲也

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ISHIMOTO Tetsuya 石本哲也

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Researcher Number	40397170
Other IDs
Affiliation (Current)	2024: 富山大学, 学術研究部医学系, 助教
Affiliation (based on the past Project Information) *help	2024: 富山大学, 学術研究部医学系, 助教 2020 – 2022: 富山大学, 学術研究部医学系, 助教 2011 – 2018: 富山大学, 大学院医学薬学研究部(医学), 助教 2012: 富山大学, 大学院・医学薬学研究部(医学), 助教 2010: 富山大学, 医学薬学研究部分子神経科学講座, 助教 2010: University of Toyama, 大学院・医学薬学研究部(医学), 助教 2008 – 2009: University of Toyama, 医学薬学研究部・分子神経科学講座, 助教
Review Section/Research Field	Principal Investigator Basic Section 46020:Anatomy and histopathology of nervous system-related / Basic Section 51010:Basic brain sciences-related / Biomolecular chemistry / Brain biometrics / Laboratory animal science / Neurochemistry/Neuropharmacology
Keywords	Principal Investigator ルシフェラーゼ / トランスジェニックマウス / 脳 / オリゴデンドロサイト / ミエリン / イメージング / リン酸化 / CREB / 生体イメージング / BCAS1 … More / BAC / 蛋白質 / 生物発光 / 細胞骨格 / BRET / アルツハイマー病 / アクチン / 活性酸素 / 抗うつ剤 / うつ病 / 発光計測 / ＣＲＥＢ Less

新しい観察法によるミエリン形成メカニズムの解明Principal Investigator
- Principal Investigator
  
  石本哲也
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 46020:Anatomy and histopathology of nervous system-related
- Research Institution
  University of Toyama
Testing the Adult Myelination Hypothesis by Luminescence Observation and Manipulation of Myelin FormationPrincipal Investigator
- Principal Investigator
  
  Ishimoto Tetsuya
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 51010:Basic brain sciences-related
- Research Institution
  University of Toyama
Development of Chemical CALI method and application for modulation of cellular proteinPrincipal Investigator
- Principal Investigator
  
  ISHIMOTO Tetsuya
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biomolecular chemistry
- Research Institution
  University of Toyama
Analysis of recovery mechanism from depression by in vivo imaging of CREB phosphorylationPrincipal Investigator
- Principal Investigator
  
  Ishimoto Tetsuya
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Brain biometrics
- Research Institution
  University of Toyama
Generation of a transgenic mouse which can be used for the in vivo detection of CREB phosphorylatioPrincipal Investigator
- Principal Investigator
  
  ISHIMOTO Tetsuya
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Laboratory animal science
- Research Institution
  University of Toyama
Monitoring of CREB phosphorylation in single live neuron using split luciferasePrincipal Investigator
- Principal Investigator
  
  ISHIMOTO Tetsuya
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  University of Toyama

All 2022 2017 2015 2014 2013 2012 2011 2010 2009 2008 Other

All Journal Article Presentation Patent

[Journal Article] A New Method for Albuminuria Measurement Using a Specific Reaction between Albumin and the Luciferin of the Firefly Squid Watasenia scintillans2022
- Author(s)
  Ishimoto Tetsuya、Okada Takuya、Fujisaka Shiho、Yagi Kunimasa、Tobe Kazuyuki、Toyooka Naoki、Mori Hisashi
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 23 Issue: 15 Pages: 8342-8342
- DOI
  10.3390/ijms23158342
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K10300, KAKENHI-PROJECT-22K10875, KAKENHI-PROJECT-20K07712, KAKENHI-PROJECT-20K08882
[Journal Article] Control of Actin Polymerization via Reactive Oxygen Species Generation using Light or Radiation.2022
- Author(s)
  Ishimoto T., Mori H.
- Journal Title
  
  Front. Cell. Dev. Biol.
  
  Volume: 10 Pages: 1014008-1014008
- DOI
  10.3389/fcell.2022.1014008
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07712
[Journal Article] In vivo imaging of CREB phosphorylation in awake-mouse brain.2015
- Author(s)
  Ishimoto, T., Mano, H., Mori, H.
- Journal Title
  
  Sci. Rep.
  
  Volume: 5 Issue: 1 Pages: 9757-9757
- DOI
  10.1038/srep09757
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-15H01279, KAKENHI-PROJECT-25350998
[Journal Article] Identification of a Novel Protein Kinase A Inhibitor by Bioluminescence-Based Screening2015
- Author(s)
  Ishimoto T, Azechi K, Mori H.
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 38 Issue: 12 Pages: 1969-1974
- DOI
  10.1248/bpb.b15-00566
- NAID
  130005112632
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25350998
[Journal Article] Discovery of Novel Adenylyl Cyclase Inhibitor by Cell-Based Screening2014
- Author(s)
  Mano H, Ishimoto T, Okada T, Toyooka N, Mori H.
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 37 Issue: 10 Pages: 1689-1693
- DOI
  10.1248/bpb.b14-00283
- NAID
  130004693794
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25350998
[Journal Article] Regulation of gene expression in retrovirus vectors by X-ray and proton beam radiation with artificially constructed promoters.2012
- Author(s)
  Ogawa, R., Morii, A., Watanabe, A., Cui, Z. G., Kagiya, G.,Fukuda, S., Kume, K., Hasegawa, T., Hatashita, M., Izumi, H., Ishimoto, T.,Feril, L. B.
- Journal Title
  
  J. Gen. Med.
  
  Volume: 14 Pages: 316-327
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23650231
[Journal Article] Measuring CREB activation using bioluminescent probes that detect KID-KIX interaction in living cells.2012
- Author(s)
  Ishimoto T., Mano H., Ozawa T., Mori H.
- Journal Title
  
  Bioconjugate Chemistry
  
  Volume: accepted
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23650231
[Journal Article] Measuring CREB activation using bioluminescent probes that detect KID-KIX interaction in living cells2012
- Author(s)
  Ishimoto, T., Mano, H., Ozawa, T., Mori, H.
- Journal Title
  
  Bioconjug. Chem
  
  Volume: 23 Pages: 923-932
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23650231
[Journal Article] Measuring CREB activation using bioluminescent probes that detect KID-KIX interaction in living cells.2012
- Author(s)
  T. Ishimoto, H. Mano, T. Ozawa and H. Mori
- Journal Title
  
  Bioconjugate Chem.
  
  Volume: 23 Issue: 5 Pages: 923-932
- DOI
  10.1021/bc200491j
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21675001, KAKENHI-PROJECT-23650231
[Journal Article] Purification of enzymatically inactive peptidylarginine deiminase type 6 from mouse ovary that reveals hexameric structure different from other dimeric isoforms.2011
- Author(s)
  Taki, H., Gomi, T., Knuckley, B., Thompson, P. R., Vugrek, O., Hirata, K., Miyahara, T., Shinoda, K., Hounoki, H., Sugiyama, E., Usui, I., Urakaze, M., Tobe,K., Ishimoto, T., Inoue, R., Tanaka, A., Mano, H., Ogawa, H., Mori, H.
- Journal Title
  
  Adv. Biosci. Biotech
  
  Volume: 2 Pages: 304-310
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23650231
[Journal Article] Bioluminescence imaging of Arc expression enables detection of activity-dependent and plastic changes in the visual cortex of adult mice.2011
- Author(s)
  Izumi,H., Ishimoto, T., Yamamoto, H., Nishijo,H., Mori, H.
- Journal Title
  
  Brain Struct. Funct
  
  Volume: 216 Pages: 91-104
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23650231
[Journal Article] Real-time monitoring of actin polymerization in living cells using split luciferase.2011
- Author(s)
  Ishimoto T., Ozawa T., Mori H.
- Journal Title
  
  Bioconjugate Chemistry
  
  Volume: 22 Issue: 2 Pages: 1136-1144
- DOI
  10.1007/s00429-010-0297-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23650231
[Journal Article] Real-time monitoring of actin polymerization in living cells using split luciferase2011
- Author(s)
  Ishimoto, T., Ozawa, T., Mori,H.
- Journal Title
  
  Bioconjug. Chem
  
  Volume: 22 Pages: 1136-1144
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23650231
[Journal Article] Bioluminescence imaging of Arc expression enables detection of activity-dependent and plastic changes in the visual cortex of adult mice.
- Author(s)
  Izumi H, Ishimoto T, Yamamoto H, Nishijo H, Mori H.
- Journal Title
  
  Brain Struct Funct. in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20700331
[Journal Article] Real-time monitoring of actin polymerization in living cells using split luciferase.
- Author(s)
  Ishimoto T, Ozawa T, Mori H.
- Journal Title
  
  Bioconjugate Chemistry in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20700331
[Patent] 神経活動を可視化するプローブ2009
- Inventor(s)
  石本哲也, 森寿, 和泉宏謙
- Industrial Property Rights Holder
  富山大学
- Filing Date
  2009-08-12
- Overseas
- Data Source
  KAKENHI-PROJECT-20700331
[Patent] 神経活動を可視化するプローブ2009
- Inventor(s)
  石本哲也、森寿、和泉宏謙
- Industrial Property Rights Holder
  富山大学
- Filing Date
  2009-08-12
- Overseas
- Data Source
  KAKENHI-PROJECT-20700331
[Patent] 記憶形成の神経活動を可視化するプローブ2008
- Inventor(s)
  石本哲也, 森寿, 和泉宏謙
- Industrial Property Rights Holder
  富山大学
- Industrial Property Number
  2008-207546
- Filing Date
  2008-08-12
- Data Source
  KAKENHI-PROJECT-20700331
[Patent] 記憶形成の神経活動を可視化するプローブ2008
- Inventor(s)
  石本哲也、森寿、和泉宏謙
- Industrial Property Rights Holder
  富山大学
- Industrial Property Number
  2008-207546
- Filing Date
  2008-08-12
- Data Source
  KAKENHI-PROJECT-20700331
[Presentation] ホタルイカの発光を用いた尿中アルブミン定量法開発2022
- Author(s)
  石本哲也、岡田卓哉、藤坂志帆、八木邦公、戸邉一之、豊岡尚樹、森寿
- Organizer
  日本分子生物学会
- Data Source
  KAKENHI-PROJECT-20K07712
[Presentation] ルシフェラーゼを用いたChemical CALI技術の構築2017
- Author(s)
  石本哲也、森寿
- Organizer
  日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16K01912
[Presentation] 発光蛋白質を用いた生体脳内CREBリン酸化の可視化2015
- Author(s)
  石本哲也, 森寿.
- Organizer
  日本バイオイメージング学会学術集会
- Place of Presentation
  東京
- Year and Date
  2015-09-27
- Data Source
  KAKENHI-PROJECT-25350998
[Presentation] Correlation analysis between remote memory and CREB phosphorylation in cerebral cortex using in vivo imaging2015
- Author(s)
  Ishimoto T, Mori H.
- Organizer
  45th annual meeting of Society of Neuroscience
- Place of Presentation
  chicago
- Year and Date
  2015-10-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25350998
[Presentation] 生体脳内CREBリン酸化可視化2015
- Author(s)
  石本哲也
- Organizer
  第２回可視化マウス研究会
- Place of Presentation
  神戸
- Year and Date
  2015-12-02
- Invited
- Data Source
  KAKENHI-PROJECT-25350998
[Presentation] 発光プローブ蛋白質を用いたCREBリン酸化経路阻害化合物のスクリーニング2015
- Author(s)
  石本哲也, 真野寛生, 畦地健司, 森寿
- Organizer
  日本分子生物学会
- Place of Presentation
  神戸
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-25350998
[Presentation] 生体脳でのCREBリン酸化イメージング2013
- Author(s)
  石本哲也、眞野寛生、森寿
- Organizer
  日本バイオイメージング学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-25350998
[Presentation] CREBリン酸化検出プローブによるマウス生体脳イメージング2013
- Author(s)
  石本哲也、眞野寛生、森寿
- Organizer
  日本分子生物学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-25350998
[Presentation] Analysis of Newly Identified Paranodal Protein BCAS1 in the Schwann cell2012
- Author(s)
  石本哲也、井上蘭、小池正人、内山安男、森寿
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  マリンメッセ福岡
- Data Source
  KAKENHI-PROJECT-23650231
[Presentation] 生物発光を用いたCREBリン酸化検出2011
- Author(s)
  石本哲也,眞野寛生,小澤岳昌,森寿
- Organizer
  第34回日本神経科学大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23650231
[Presentation] Actin polymerization and its role in UV-induced HEK293T cell death.2011
- Author(s)
  石本哲也, 小澤岳昌, 森寿
- Organizer
  第84回日本薬理学会年会
- Place of Presentation
  横浜
- Year and Date
  2011-03-24
- Data Source
  KAKENHI-PROJECT-20700331
[Presentation] Monitoring of CREB phosphorylation in live cells using split luciferase technique.2011
- Author(s)
  Ishimoto T., Mano H., Ozawa T., and Mori H.
- Organizer
  Society For Neuroscience's 41th annual meeting
- Place of Presentation
  Washington DC, USA
- Data Source
  KAKENHI-PROJECT-23650231
[Presentation] Monitoring of CREB phosphorylation in live cells using split luciferase technique2011
- Author(s)
  Ishimoto T., Mano H., Ozawa T., and Mori H
- Organizer
  Society For Neuroscience's 41th annual meeting
- Place of Presentation
  Washington DC, USA
- Data Source
  KAKENHI-PROJECT-23650231
[Presentation] 生物発光を用いたCREBリン酸化検出2011
- Author(s)
  石本哲也, 眞野寛生, 小澤岳昌, 森寿
- Organizer
  第34回日本神経科学大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23650231
[Presentation] 発光蛋白質を用いたCREB活性化の計測2011
- Author(s)
  石本哲也,眞野寛生,小澤岳昌,森寿
- Organizer
  CRESTシンポジウム「新しい計測で生命に迫る」
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23650231
[Presentation] Detection of CREB phosphorylation in live cells using a bioluminescence based method.2011
- Author(s)
  Ishimoto T., Mano H., Ozawa T., and Mori H.
- Organizer
  The 6th International conference of Neurons and Brain Diseases
- Place of Presentation
  Toyama
- Data Source
  KAKENHI-PROJECT-23650231
[Presentation] Actin polymerization and its role in UV-induced HEK293T cell death2011
- Author(s)
  石本哲也, 小澤岳昌, 森寿
- Organizer
  第84回日本薬理学会年会
- Place of Presentation
  (誌上発表(学会中止のため))
- Year and Date
  2011-03-24
- Data Source
  KAKENHI-PROJECT-20700331
[Presentation] Detection of CREB activation in living cells using a bioluminescence-based method.2011
- Author(s)
  Ishimoto T., Mano H., Ozawa T., and Mori H.
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23650231
[Presentation] Bioluminescence imaging of Arc gene expression detects neural activity-dependent changes in vivo.2010
- Author(s)
  和泉宏謙, 石本哲也, 山本博, 西条寿夫, 森寿
- Organizer
  第33回日本神経科学大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-20700331
[Presentation] Real-time measurement of actin polymerization in live cells : Transient upregulation in F-actin after UV irradiation and its protective effect on cell death.2010
- Author(s)
  石本哲也, 小澤岳昌, 森寿
- Organizer
  第33回日本神経科学大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-20700331
[Presentation] Real-time measurement of F-actin content during cell death using a bioluminescence based method.2009
- Author(s)
  石本哲也, 和泉宏謙, 小澤岳昌, 森寿
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-12-09
- Data Source
  KAKENHI-PROJECT-20700331
[Presentation] Real-time measurement of F-actin content during cell death using a bioluminescence based method2009
- Author(s)
  石本哲也, 和泉宏謙, 小澤岳昌, 森寿
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-12-09
- Data Source
  KAKENHI-PROJECT-20700331
[Presentation] スプリットルシフェラーゼを用いたアクチン重合の検出2009
- Author(s)
  石本哲也、和泉宏謙、小澤岳昌、森寿
- Organizer
  日本薬理学会
- Place of Presentation
  横浜
- Year and Date
  2009-03-16
- Data Source
  KAKENHI-PROJECT-20700331
[Presentation] Detection of protein-protein interaction in living cells using a bioluminescence based method2009
- Author(s)
  Ishimoto T., Izumi H., Ozawa T., Mori H
- Organizer
  The 40th Annual Meeting of Society for Neuroscience
- Place of Presentation
  Chicago, USA
- Year and Date
  2009-10-19
- Data Source
  KAKENHI-PROJECT-20700331
[Presentation] 生物発光を利用した細胞内アクチン重合の計測2009
- Author(s)
  石本哲也, 和泉宏謙, 小澤岳昌, 森寿
- Organizer
  第32回日本神経科学大会
- Place of Presentation
  名古屋
- Year and Date
  2009-09-17
- Data Source
  KAKENHI-PROJECT-20700331
[Presentation] Detection of protein-protein interaction in living cells using a bioluminescence based method.2009
- Author(s)
  Ishimoto T., Izumi H., Ozawa T., Mori H.
- Organizer
  The 40th Annual Meeting of Society for Neuroscience
- Place of Presentation
  Chicago, USA.
- Year and Date
  2009-10-19
- Data Source
  KAKENHI-PROJECT-20700331
[Presentation] スプリットルシフェラーゼを用いたアクチン重合の検出2008
- Author(s)
  石本哲也, 和泉宏謙, 小澤岳昌, 森寿
- Organizer
  第82回日本薬理学会年会
- Place of Presentation
  横浜
- Year and Date
  2008-03-16
- Data Source
  KAKENHI-PROJECT-20700331
[Presentation] In vivo imaging of CREB phosphorylation using a novel transgenic mouse line expressing bioluminescence probes
- Author(s)
  T Ishimoto, H Mano, H Mori.
- Organizer
  Society For Neuroscience
- Place of Presentation
  Washington DC
- Year and Date
  2014-11-15 – 2014-11-19
- Data Source
  KAKENHI-PROJECT-25350998
[Presentation] スプリットルシフェラーゼを用いたマウス脳内CREBのリン酸化イメージング
- Author(s)
  石本哲也, 眞野寛生, 森寿
- Organizer
  第37回日本神経科学大会
- Place of Presentation
  横浜
- Year and Date
  2014-09-11 – 2014-09-13
- Data Source
  KAKENHI-PROJECT-25350998

1. 和泉宏謙 (00377342)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. YAGI Kunimasa

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 森寿

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 小澤岳昌

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Ishimoto Tetsuya 石本 哲也

ISHIMOTO Tetsuya 石本 哲也

Research Projects

Research Products

Co-Researchers

新しい観察法によるミエリン形成メカニズムの解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Testing the Adult Myelination Hypothesis by Luminescence Observation and Manipulation of Myelin FormationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of Chemical CALI method and application for modulation of cellular proteinPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of recovery mechanism from depression by in vivo imaging of CREB phosphorylationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Generation of a transgenic mouse which can be used for the in vivo detection of CREB phosphorylatioPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Monitoring of CREB phosphorylation in single live neuron using split luciferasePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] A New Method for Albuminuria Measurement Using a Specific Reaction between Albumin and the Luciferin of the Firefly Squid Watasenia scintillans2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Control of Actin Polymerization via Reactive Oxygen Species Generation using Light or Radiation.2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] In vivo imaging of CREB phosphorylation in awake-mouse brain.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Identification of a Novel Protein Kinase A Inhibitor by Bioluminescence-Based Screening2015

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Discovery of Novel Adenylyl Cyclase Inhibitor by Cell-Based Screening2014

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Regulation of gene expression in retrovirus vectors by X-ray and proton beam radiation with artificially constructed promoters.2012

Author(s)

Journal Title

Data Source

[Journal Article] Measuring CREB activation using bioluminescent probes that detect KID-KIX interaction in living cells.2012

Author(s)

Journal Title

Data Source

Ishimoto Tetsuya 石本哲也

ISHIMOTO Tetsuya 石本哲也