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Ishimoto Tetsuya  石本 哲也

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石本 哲也  イシモト テツヤ

ISHIMOTO Tetsuya  石本 哲也

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Researcher Number 40397170
Other IDs
Affiliation (Current) 2022: 富山大学, 学術研究部医学系, 助教
Affiliation (based on the past Project Information) *help 2020 – 2021: 富山大学, 学術研究部医学系, 助教
2011 – 2018: 富山大学, 大学院医学薬学研究部(医学), 助教
2012: 富山大学, 大学院・医学薬学研究部(医学), 助教
2010: 富山大学, 医学薬学研究部分子神経科学講座, 助教
2010: University of Toyama, 大学院・医学薬学研究部(医学), 助教
2008 – 2009: University of Toyama, 医学薬学研究部・分子神経科学講座, 助教
Review Section/Research Field
Principal Investigator
Neurochemistry/Neuropharmacology / Laboratory animal science / Brain biometrics / Biomolecular chemistry / Basic Section 51010:Basic brain sciences-related
Keywords
Principal Investigator
ルシフェラーゼ / トランスジェニックマウス / CREB / リン酸化 / イメージング / CREB / 発光計測 / うつ病 / 抗うつ剤 / 活性酸素 … More / アクチン / アルツハイマー病 / BRET / 細胞骨格 / 生物発光 / 蛋白質 / ミエリン / 生体イメージング / 脳 Less
  • Research Projects

    (5 results)
  • Research Products

    (45 results)
  • Co-Researchers

    (3 People)
  •  ミエリン形成の発光観察と操作によるアダルトミエリネーション仮説の検証Principal Investigator

    • Principal Investigator
      石本 哲也
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 51010:Basic brain sciences-related
    • Research Institution
      University of Toyama
  •  Development of Chemical CALI method and application for modulation of cellular proteinPrincipal Investigator

    • Principal Investigator
      ISHIMOTO Tetsuya
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biomolecular chemistry
    • Research Institution
      University of Toyama
  •  Analysis of recovery mechanism from depression by in vivo imaging of CREB phosphorylationPrincipal Investigator

    • Principal Investigator
      Ishimoto Tetsuya
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Brain biometrics
    • Research Institution
      University of Toyama
  •  Generation of a transgenic mouse which can be used for the in vivo detection of CREB phosphorylatioPrincipal Investigator

    • Principal Investigator
      ISHIMOTO Tetsuya
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Laboratory animal science
    • Research Institution
      University of Toyama
  •  Monitoring of CREB phosphorylation in single live neuron using split luciferasePrincipal Investigator

    • Principal Investigator
      ISHIMOTO Tetsuya
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Neurochemistry/Neuropharmacology
    • Research Institution
      University of Toyama

All 2017 2015 2014 2013 2012 2011 2010 2009 2008 Other

All Journal Article Presentation Patent

  • [Journal Article] In vivo imaging of CREB phosphorylation in awake-mouse brain.2015

    • Author(s)
      Ishimoto, T., Mano, H., Mori, H.
    • Journal Title

      Scientific Reports

      Volume: 5 Pages: 9757-9757

    • DOI

      10.1038/srep09757

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PUBLICLY-15H01279, KAKENHI-PROJECT-25350998
  • [Journal Article] Identification of a Novel Protein Kinase A Inhibitor by Bioluminescence-Based Screening2015

    • Author(s)
      Ishimoto T, Azechi K, Mori H.
    • Journal Title

      Biol. Pharm. Bull.

      Volume: 38 Issue: 12 Pages: 1969-1974

    • DOI

      10.1248/bpb.b15-00566

    • NAID

      130005112632

    • ISSN
      0918-6158, 1347-5215
    • Language
      English
    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25350998
  • [Journal Article] Discovery of Novel Adenylyl Cyclase Inhibitor by Cell-Based Screening2014

    • Author(s)
      Mano H, Ishimoto T, Okada T, Toyooka N, Mori H.
    • Journal Title

      Biol. Pharm. Bull.

      Volume: 37 Issue: 10 Pages: 1689-1693

    • DOI

      10.1248/bpb.b14-00283

    • NAID

      130004693794

    • ISSN
      0918-6158, 1347-5215
    • Language
      English
    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25350998
  • [Journal Article] Regulation of gene expression in retrovirus vectors by X-ray and proton beam radiation with artificially constructed promoters.2012

    • Author(s)
      Ogawa, R., Morii, A., Watanabe, A., Cui, Z. G., Kagiya, G.,Fukuda, S., Kume, K., Hasegawa, T., Hatashita, M., Izumi, H., Ishimoto, T.,Feril, L. B.
    • Journal Title

      J. Gen. Med.

      Volume: 14 Pages: 316-327

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23650231
  • [Journal Article] Measuring CREB activation using bioluminescent probes that detect KID-KIX interaction in living cells.2012

    • Author(s)
      Ishimoto T., Mano H., Ozawa T., Mori H.
    • Journal Title

      Bioconjugate Chemistry

      Volume: accepted

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23650231
  • [Journal Article] Measuring CREB activation using bioluminescent probes that detect KID-KIX interaction in living cells2012

    • Author(s)
      Ishimoto, T., Mano, H., Ozawa, T., Mori, H.
    • Journal Title

      Bioconjug. Chem

      Volume: 23 Pages: 923-932

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23650231
  • [Journal Article] Measuring CREB activation using bioluminescent probes that detect KID−KIX interaction in living cells.2012

    • Author(s)
      T. Ishimoto, H. Mano, T. Ozawa and H. Mori
    • Journal Title

      Bioconjugate Chemistry

      Volume: 23 Pages: 923-932

    • DOI

      10.1021/bc200491j

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21675001, KAKENHI-PROJECT-23650231
  • [Journal Article] Purification of enzymatically inactive peptidylarginine deiminase type 6 from mouse ovary that reveals hexameric structure different from other dimeric isoforms.2011

    • Author(s)
      Taki, H., Gomi, T., Knuckley, B., Thompson, P. R., Vugrek, O., Hirata, K., Miyahara, T., Shinoda, K., Hounoki, H., Sugiyama, E., Usui, I., Urakaze, M., Tobe,K., Ishimoto, T., Inoue, R., Tanaka, A., Mano, H., Ogawa, H., Mori, H.
    • Journal Title

      Adv. Biosci. Biotech

      Volume: 2 Pages: 304-310

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23650231
  • [Journal Article] Bioluminescence imaging of Arc expression enables detection of activity-dependent and plastic changes in the visual cortex of adult mice.2011

    • Author(s)
      Izumi,H., Ishimoto, T., Yamamoto, H., Nishijo,H., Mori, H.
    • Journal Title

      Brain Struct. Funct

      Volume: 216 Pages: 91-104

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23650231
  • [Journal Article] Bioluminescence imaging of Arc expression enables detection of activity-dependent and plastic changes in the visual cortex of adult mice.2011

    • Author(s)
      Ishimoto T., Ozawa T., Mori H.
    • Journal Title

      Brain Structure and Function

      Volume: 22 Pages: 91-104

    • DOI

      10.1007/s00429-010-0297-2

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23650231
  • [Journal Article] Real-time monitoring of actin polymerization in living cells using split luciferase2011

    • Author(s)
      Ishimoto, T., Ozawa, T., Mori,H.
    • Journal Title

      Bioconjug. Chem

      Volume: 22 Pages: 1136-1144

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23650231
  • [Journal Article] Bioluminescence imaging of Arc expression enables detection of activity-dependent and plastic changes in the visual cortex of adult mice.

    • Author(s)
      Izumi H, Ishimoto T, Yamamoto H, Nishijo H, Mori H.
    • Journal Title

      Brain Struct Funct. in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20700331
  • [Journal Article] Real-time monitoring of actin polymerization in living cells using split luciferase.

    • Author(s)
      Ishimoto T, Ozawa T, Mori H.
    • Journal Title

      Bioconjugate Chemistry in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20700331
  • [Patent] 神経活動を可視化するプローブ2009

    • Inventor(s)
      石本哲也, 森寿, 和泉宏謙
    • Industrial Property Rights Holder
      富山大学
    • Filing Date
      2009-08-12
    • Overseas
    • Data Source
      KAKENHI-PROJECT-20700331
  • [Patent] 神経活動を可視化するプローブ2009

    • Inventor(s)
      石本哲也、森寿、和泉宏謙
    • Industrial Property Rights Holder
      富山大学
    • Filing Date
      2009-08-12
    • Overseas
    • Data Source
      KAKENHI-PROJECT-20700331
  • [Patent] 記憶形成の神経活動を可視化するプローブ2008

    • Inventor(s)
      石本哲也, 森寿, 和泉宏謙
    • Industrial Property Rights Holder
      富山大学
    • Industrial Property Number
      2008-207546
    • Filing Date
      2008-08-12
    • Data Source
      KAKENHI-PROJECT-20700331
  • [Patent] 記憶形成の神経活動を可視化するプローブ2008

    • Inventor(s)
      石本哲也、森寿、和泉宏謙
    • Industrial Property Rights Holder
      富山大学
    • Industrial Property Number
      2008-207546
    • Filing Date
      2008-08-12
    • Data Source
      KAKENHI-PROJECT-20700331
  • [Presentation] ルシフェラーゼを用いたChemical CALI技術の構築2017

    • Author(s)
      石本哲也、森寿
    • Organizer
      日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-16K01912
  • [Presentation] 発光蛋白質を用いた生体脳内CREBリン酸化の可視化2015

    • Author(s)
      石本哲也, 森寿.
    • Organizer
      日本バイオイメージング学会学術集会
    • Place of Presentation
      東京
    • Year and Date
      2015-09-27
    • Data Source
      KAKENHI-PROJECT-25350998
  • [Presentation] Correlation analysis between remote memory and CREB phosphorylation in cerebral cortex using in vivo imaging2015

    • Author(s)
      Ishimoto T, Mori H.
    • Organizer
      45th annual meeting of Society of Neuroscience
    • Place of Presentation
      chicago
    • Year and Date
      2015-10-17
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25350998
  • [Presentation] 生体脳内CREBリン酸化可視化2015

    • Author(s)
      石本哲也
    • Organizer
      第2回可視化マウス研究会
    • Place of Presentation
      神戸
    • Year and Date
      2015-12-02
    • Invited
    • Data Source
      KAKENHI-PROJECT-25350998
  • [Presentation] 発光プローブ蛋白質を用いたCREBリン酸化経路阻害化合物のスクリーニング2015

    • Author(s)
      石本哲也, 真野寛生, 畦地健司, 森寿
    • Organizer
      日本分子生物学会
    • Place of Presentation
      神戸
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PROJECT-25350998
  • [Presentation] 生体脳でのCREBリン酸化イメージング2013

    • Author(s)
      石本哲也、眞野寛生、森寿
    • Organizer
      日本バイオイメージング学会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-25350998
  • [Presentation] CREBリン酸化検出プローブによるマウス生体脳イメージング2013

    • Author(s)
      石本哲也、眞野寛生、森寿
    • Organizer
      日本分子生物学会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-25350998
  • [Presentation] Analysis of Newly Identified Paranodal Protein BCAS1 in the Schwann cell2012

    • Author(s)
      石本哲也、井上 蘭、小池正人、内山安男、森 寿
    • Organizer
      第37回日本分子生物学会年会
    • Place of Presentation
      マリンメッセ福岡
    • Data Source
      KAKENHI-PROJECT-23650231
  • [Presentation] 生物発光を用いたCREBリン酸化検出2011

    • Author(s)
      石本哲也,眞野寛生,小澤岳昌,森 寿
    • Organizer
      第34回日本神経科学大会
    • Place of Presentation
      横 浜
    • Data Source
      KAKENHI-PROJECT-23650231
  • [Presentation] Actin polymerization and its role in UV-induced HEK293T cell death.2011

    • Author(s)
      石本哲也, 小澤岳昌, 森寿
    • Organizer
      第84回日本薬理学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2011-03-24
    • Data Source
      KAKENHI-PROJECT-20700331
  • [Presentation] Monitoring of CREB phosphorylation in live cells using split luciferase technique.2011

    • Author(s)
      Ishimoto T., Mano H., Ozawa T., and Mori H.
    • Organizer
      Society For Neuroscience's 41th annual meeting
    • Place of Presentation
      Washington DC, USA
    • Data Source
      KAKENHI-PROJECT-23650231
  • [Presentation] Monitoring of CREB phosphorylation in live cells using split luciferase technique2011

    • Author(s)
      Ishimoto T., Mano H., Ozawa T., and Mori H
    • Organizer
      Society For Neuroscience's 41th annual meeting
    • Place of Presentation
      Washington DC, USA
    • Data Source
      KAKENHI-PROJECT-23650231
  • [Presentation] 生物発光を用いたCREBリン酸化検出2011

    • Author(s)
      石本 哲也, 眞野 寛生, 小澤 岳昌, 森 寿
    • Organizer
      第34回日本神経科学大会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-23650231
  • [Presentation] 発光蛋白質を用いたCREB活性化の計測2011

    • Author(s)
      石本哲也,眞野寛生,小澤岳昌,森 寿
    • Organizer
      CRESTシンポジウム「新しい計測で生命に迫る 」
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23650231
  • [Presentation] Detection of CREB phosphorylation in live cells using a bioluminescence based method.2011

    • Author(s)
      Ishimoto T., Mano H., Ozawa T., and Mori H.
    • Organizer
      The 6th International conference of Neurons and Brain Diseases
    • Place of Presentation
      Toyama
    • Data Source
      KAKENHI-PROJECT-23650231
  • [Presentation] Actin polymerization and its role in UV-induced HEK293T cell death2011

    • Author(s)
      石本哲也, 小澤岳昌, 森寿
    • Organizer
      第84回日本薬理学会年会
    • Place of Presentation
      (誌上発表(学会中止のため))
    • Year and Date
      2011-03-24
    • Data Source
      KAKENHI-PROJECT-20700331
  • [Presentation] Detection of CREB activation in living cells using a bioluminescence-based method.2011

    • Author(s)
      Ishimoto T., Mano H., Ozawa T., and Mori H.
    • Organizer
      第34回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-23650231
  • [Presentation] Bioluminescence imaging of Arc gene expression detects neural activity-dependent changes in vivo.2010

    • Author(s)
      和泉宏謙, 石本哲也, 山本博, 西条寿夫, 森寿
    • Organizer
      第33回日本神経科学大会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-20700331
  • [Presentation] Real-time measurement of actin polymerization in live cells : Transient upregulation in F-actin after UV irradiation and its protective effect on cell death.2010

    • Author(s)
      石本哲也, 小澤岳昌, 森寿
    • Organizer
      第33回日本神経科学大会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-20700331
  • [Presentation] Real-time measurement of F-actin content during cell death using a bioluminescence based method.2009

    • Author(s)
      石本哲也, 和泉宏謙, 小澤岳昌, 森寿
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2009-12-09
    • Data Source
      KAKENHI-PROJECT-20700331
  • [Presentation] Real-time measurement of F-actin content during cell death using a bioluminescence based method2009

    • Author(s)
      石本哲也, 和泉宏謙, 小澤岳昌, 森寿
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2009-12-09
    • Data Source
      KAKENHI-PROJECT-20700331
  • [Presentation] スプリットルシフェラーゼを用いたアクチン重合の検出2009

    • Author(s)
      石本哲也、和泉宏謙、小澤岳昌、森寿
    • Organizer
      日本薬理学会
    • Place of Presentation
      横浜
    • Year and Date
      2009-03-16
    • Data Source
      KAKENHI-PROJECT-20700331
  • [Presentation] Detection of protein-protein interaction in living cells using a bioluminescence based method2009

    • Author(s)
      Ishimoto T., Izumi H., Ozawa T., Mori H
    • Organizer
      The 40th Annual Meeting of Society for Neuroscience
    • Place of Presentation
      Chicago, USA
    • Year and Date
      2009-10-19
    • Data Source
      KAKENHI-PROJECT-20700331
  • [Presentation] 生物発光を利用した細胞内アクチン重合の計測2009

    • Author(s)
      石本哲也, 和泉宏謙, 小澤岳昌, 森寿
    • Organizer
      第32回日本神経科学大会
    • Place of Presentation
      名古屋
    • Year and Date
      2009-09-17
    • Data Source
      KAKENHI-PROJECT-20700331
  • [Presentation] Detection of protein-protein interaction in living cells using a bioluminescence based method.2009

    • Author(s)
      Ishimoto T., Izumi H., Ozawa T., Mori H.
    • Organizer
      The 40th Annual Meeting of Society for Neuroscience
    • Place of Presentation
      Chicago, USA.
    • Year and Date
      2009-10-19
    • Data Source
      KAKENHI-PROJECT-20700331
  • [Presentation] スプリットルシフェラーゼを用いたアクチン重合の検出2008

    • Author(s)
      石本哲也, 和泉宏謙, 小澤岳昌, 森寿
    • Organizer
      第82回日本薬理学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2008-03-16
    • Data Source
      KAKENHI-PROJECT-20700331
  • [Presentation] In vivo imaging of CREB phosphorylation using a novel transgenic mouse line expressing bioluminescence probes

    • Author(s)
      T Ishimoto, H Mano, H Mori.
    • Organizer
      Society For Neuroscience
    • Place of Presentation
      Washington DC
    • Year and Date
      2014-11-15 – 2014-11-19
    • Data Source
      KAKENHI-PROJECT-25350998
  • [Presentation] スプリットルシフェラーゼを用いたマウス脳内CREBのリン酸化イメージング

    • Author(s)
      石本哲也, 眞野寛生, 森寿
    • Organizer
      第37回日本神経科学大会
    • Place of Presentation
      横浜
    • Year and Date
      2014-09-11 – 2014-09-13
    • Data Source
      KAKENHI-PROJECT-25350998
  • 1.  和泉 宏謙 (00377342)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 2.  森 寿
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 3.  小澤 岳昌
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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