Kozako Tomohiro 小迫知弘

… Alternative Names

KOZAKO Tomohiro 小迫知弘

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Researcher Number	40398300
Other IDs
Affiliation (Current)	2026: 福岡大学, 薬学部, 准教授
Affiliation (based on the past Project Information) *help	2012 – 2025: 福岡大学, 薬学部, 准教授 2010 – 2011: 福岡大学, 薬学部, 助教 2008: Fukuoka University, 薬学部, 助教 2007: Kagoshima University, 大学院・医歯学総合研究科, 特任研究員
Review Section/Research Field	Principal Investigator Hematology / Basic Section 54010:Hematology and medical oncology-related Except Principal Investigator Hematology
Keywords	Principal Investigator ATL / HTLV-1 / エピジェネティクス / エピジェネティック / サーチュイン / SIRT1 / エピジェネティックス / 白血病 / Sirtuin / アポトーシス … More / 長寿遺伝子 / 血液免疫学 / 腫瘍免疫 / HLA / ワクチン / CTL / 免疫療法 / 免疫制御学 … More Except Principal Investigator ペプチドワクチン / CTL / HBZ / Tax / ワクチン / HTLV-1 Less

タンパク質分解誘導キメラ分子創薬による新規白血病治療法の開発Principal Investigator
- Principal Investigator
  
  小迫知弘
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Fukuoka University
Novel epigenetic control compounds induce cell death in leukemia cellsPrincipal Investigator
- Principal Investigator
  
  Kozako Tomohiro
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Fukuoka University
Novel small-molecule sirtuin inhibitors induce cell death in leukemia cellsPrincipal Investigator
- Principal Investigator
  
  Kozako Tomohiro
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Fukuoka University
Novel small-molecule sirtuin inhibitors induce cell apoptic death in leukemia cellsPrincipal Investigator
- Principal Investigator
  
  KOZAKO Tomohiro
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Fukuoka University
Development of HTLV-1 peptide vaccine for treatment and prevention of ATL
- Principal Investigator
  
  Arima Naomichi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Kagoshima University
Novel small-molecule SIRT1 inhibitors induce cell death in leukaemia cellsPrincipal Investigator
- Principal Investigator
  
  KOZAKO Tomohiro
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Fukuoka University
SIRT1, a longevity gene encoded protein, regulates apoptosis of adult T-cell leukemia cells and its inhibition by sirtinol induces apoptosisPrincipal Investigator
- Principal Investigator
  
  KOZAKO Tomohiro
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Hematology
- Research Institution
  Fukuoka University
Efficient Induction of HTLV-1-specific CTL by HTLV-1/HBc Chimeric Particle without Adjuvant as a Prophylactic for HTLV-1-associated T-cell LeukemiaPrincipal Investigator
- Principal Investigator
  
  KOZAKO Tomohiro
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Hematology
- Research Institution
  Fukuoka University
  Kagoshima University

[Book] Epigenetic Control Using Small Molecules in Cancer2020
- Author(s)
  Tomohiro Kozako, Yukihiro Itoh, Shin-ichiro Honda, Takayoshi Suzuki
- Total Pages
  483
- Publisher
  Springer Nature
- ISBN
  9783030328573
- Data Source
  KAKENHI-PROJECT-19K08851
[Book] 薬学生のための病態検査学改訂第3版2018
- Author(s)
  竹橋　正則、丹羽　和紀、高寺　恒雄、松永　俊之、三浦　雅一、小迫　知弘、木村　聡、佐藤　圭創、橋口　照人、古川　勝敏、佐藤　友紀、町田　麻依子
- Total Pages
  298
- Publisher
  南江堂
- ISBN
  9784524403578
- Data Source
  KAKENHI-PROJECT-16K09863
[Book] 薬学生のための病態検査学改訂第2版2014
- Author(s)
  編集：三浦　雅一、執筆者：竹橋　正則、丹羽　和紀、高寺　恒雄、松永　俊之、三浦　雅一、小迫　知弘、添田　秦司、木村　聡、佐藤　圭創、古川　勝敏、橋口　照人
- Total Pages
  264
- Publisher
  南江堂
- Data Source
  KAKENHI-PROJECT-24591413
[Book] T-Cell Leukemia - Characteristics, Treatment and Prevention2013
- Author(s)
  Makoto Yoshimitsu, Tomohiro Kozako and Naomichi Arima
- Total Pages
  307
- Publisher
  InTech
- Data Source
  KAKENHI-PROJECT-24591413
[Book] Major Histocompatibility Complex: Biology, Functions and Roles in Disease2012
- Author(s)
  Tomohiro Kozako, Shinya Hirata, Makoto Yoshimitsu, and Naomichi Arima
- Total Pages
  16
- Publisher
  Nova Science Publishers, Inc.
- Data Source
  KAKENHI-PROJECT-24591413
[Book] Major Histocompatibility Complex : Biology, Functions and Roles in Disease2011
- Author(s)
  Tomohiro Kozako, Shinya Hirata, Makoto Yoshimitsu, Naomichi Arima
- Total Pages
  10
- Publisher
  Nova Science Publishers, Inc.
- Data Source
  KAKENHI-PROJECT-22790921
[Book] Prophylactic and Therapeutic Approach for Adult T-cell Leukemia Based on Targeting Anti-tumor Immunity. Major Histocompatibility Complex : Biology, Functions and Roles in Disease2011
- Author(s)
  Kozako T. Hirata S, Yoshimitsu M, Arima N.
- Publisher
  Nova Science Publishers
- Data Source
  KAKENHI-PROJECT-22790921
[Journal Article] Anti-tumor activity of 5-aminoimidazole-4-carboxamide riboside with AMPK-independent cell death in human adult T-cell leukemia/lymphoma2023
- Author(s)
  Aikawa Akiyoshi、Kozako Tomohiro、Kato Naho、Ohsugi Takeo、Honda Shin-ichiro
- Journal Title
  
  European Journal of Pharmacology
  
  Volume: 961 Pages: 176180-176180
- DOI
  10.1016/j.ejphar.2023.176180
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08491
[Journal Article] CDK9 Inhibitor Induces Apoptosis, Autophagy, and Suppression of Tumor Growth in Adult T-Cell Leukemia/Lymphoma2023
- Author(s)
  Kato Naho、Kozako Tomohiro、Ohsugi Takeo、Uchida Yuichiro、Yoshimitsu Makoto、Ishitsuka Kenji、Aikawa Akiyoshi、Honda Shin-ichiro
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 46 Issue: 9 Pages: 1269-1276
- DOI
  10.1248/bpb.b23-00228
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2023-09-01
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08491
[Journal Article] SRT1720 induces SIRT1-independent cell death in adult T-cell leukemia/lymphoma2022
- Author(s)
  Tomohiro Kozako, Naho Kato, Takeo Ohsugi, Yu-Ichiro Uchida, Makoto Yoshimitsu, Kenji Ishitsuka, Yasuki Higaki, Haruna Sato, Akiyoshi Aikawa, Shin-Ichiro Honda
- Journal Title
  
  FEBS J
  
  Volume: in press Issue: 12 Pages: 1-12
- DOI
  10.1111/febs.16353
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06036, KAKENHI-PROJECT-19K08851, KAKENHI-PROJECT-22K08491
[Journal Article] Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)12021
- Author(s)
  Daniel J Klionsky、Shu Aizawa、Amal Kamal Abdel-Aziz、Sara Abdelfatah、Mahmoud Abdellatif、Asghar Abdoli、Steffen Abel、Hagai Abeliovich、Marie H Abildgaard、Yakubu Princely Abudu、Abraham Acevedo-Arozena、Iannis E Adamopoulos、Khosrow Adeli、Timon E Adolph、Annagrazia Adornetto、Elma Aflaki、Galila Agam et al.
- Journal Title
  
  Autophagy
  
  Volume: 17 Issue: 1 Pages: 1-382
- DOI
  10.1080/15548627.2020.1797280
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06375, KAKENHI-PROJECT-19K07568, KAKENHI-PROJECT-20K06501, KAKENHI-PROJECT-20K06636, KAKENHI-PROJECT-20K07896, KAKENHI-PROJECT-20K21769, KAKENHI-PLANNED-20H05772, KAKENHI-PROJECT-19H01042, KAKENHI-PROJECT-18H02439, KAKENHI-PROJECT-18H02656, KAKENHI-PROJECT-18H02807, KAKENHI-PROJECT-20J00363, KAKENHI-PROJECT-18K06210, KAKENHI-PROJECT-18K07934, KAKENHI-PROJECT-18K08079, KAKENHI-PROJECT-18K09427, KAKENHI-PROJECT-19K08851, KAKENHI-PROJECT-18KK0193, KAKENHI-PLANNED-19H05710, KAKENHI-PROJECT-18H02901, KAKENHI-PROJECT-20H02990, KAKENHI-PUBLICLY-20H05504, KAKENHI-PROJECT-19H03471, KAKENHI-PROJECT-19H03791, KAKENHI-PROJECT-20H03249, KAKENHI-PROJECT-19K09677, KAKENHI-PROJECT-20K07910, KAKENHI-PROJECT-20K08460, KAKENHI-PROJECT-20K08662, KAKENHI-PROJECT-21K07926, KAKENHI-PROJECT-20K21531, KAKENHI-PROJECT-19K24690, KAKENHI-PROJECT-23K21397
[Journal Article] Cell death induced by dorsomorphin in adult T-cell leukemia/lymphoma is AMPK-independent.2020
- Author(s)
  Aikawa A, Kozako T, Uchida Y, Yoshimitsu M, Ishitsuka K, Ohsugi T, Honda SI.
- Journal Title
  
  FEBS J.
  
  Volume: n/a Issue: 18 Pages: 4005-4015
- DOI
  10.1111/febs.15239
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08851, KAKENHI-PROJECT-18K06036
[Journal Article] Antithrombin gamma attenuates macrophage/microglia activation and brain damage after transient focal cerebral ischemia in mice2020
- Author(s)
  Nakano T, Nakamura Y, Irie K, Okano S, Morimoto M, Yamashita Y, Kozako T, Hayashi T, Honda SI, Matsuo K, Kamimura H, Ishikura H, Egawa T, Mishima K.
- Journal Title
  
  Life Sci
  
  Volume: 252 Pages: 117665-117665
- DOI
  10.1016/j.lfs.2020.117665
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08851, KAKENHI-PROJECT-20K07215, KAKENHI-PROJECT-19K16432
[Journal Article] サーチュインを標的とした新規成人T細胞白血病治療法の開発2019
- Author(s)
  小迫知弘、鈴木孝禎
- Journal Title
  
  細胞
  
  Volume: 51 Pages: 38-40
- Data Source
  KAKENHI-PROJECT-19K08851
[Journal Article] A novel mouse model of adult T‐cell leukemia cell invasion into the spinal cord.2019
- Author(s)
  Ohsugi, T., Tanaka, S., Iwasaki, K., Nagano, Y., Kozako, T., Matsuda, K., Hirose, T. and Takehana, K.
- Journal Title
  
  Animal Model Exp. Med.
  
  Volume: 2 Issue: 1 Pages: 64-67
- DOI
  10.1002/ame2.12053
- NAID
  120006901053
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06036, KAKENHI-PROJECT-19K08851
[Journal Article] High expression of NAMPT in adult T-cell leukemia/lymphoma and anti-tumor activity of a NAMPT inhibitor2019
- Author(s)
  Kozako Tomohiro、Aikawa Akiyoshi、Ohsugi Takeo、Uchida Yu-ichiro、Kato Naho、Sato Keisuke、Ishitsuka Kenji、Yoshimitsu Makoto、Honda Shin-ichiro
- Journal Title
  
  European Journal of Pharmacology
  
  Volume: 865 Pages: 172738-172738
- DOI
  10.1016/j.ejphar.2019.172738
- NAID
  120006901050
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06036, KAKENHI-PROJECT-19K08851
[Journal Article] In vitro effects of arsenic trioxide, interferon α and zidovudine in adult T cell leukemia/lymphoma cells.2018
- Author(s)
  Hachiman M, Yoshimitsu M, Ezinne C, Kuroki A, Kozako T, Arima N.
- Journal Title
  
  Oncol Lett.
  
  Volume: 16 Pages: 1305-1311
- DOI
  10.3892/ol.2018.8771
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09863
[Journal Article] Novel small molecule SIRT2 inhibitors induce cell death in leukemic cell lines.2018
- Author(s)
  Kozako, T., Mellini, P., Ohsugi, T., Aikawa, A., Uchida, Y. I., Honda, S. I., Suzuki, T.
- Journal Title
  
  BMC Cancer
  
  Volume: 18 Issue: 1 Pages: 791-791
- DOI
  10.1186/s12885-018-4710-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06036, KAKENHI-PROJECT-16K09863
[Journal Article] The small molecule STF-62247 induces apoptotic and autophagic cell death in leukemic cells2018
- Author(s)
  Kozako T*, Sato K*, Uchida Y, Kato N, Aikawa A, Ogata K, Kamimura H, Uemura H, Yoshimitsu M, Ishitsuka K, Higaki Y, Tanaka H, Honda SI, Soeda S. (*: Co-first authors)
- Journal Title
  
  Oncotarget
  
  Volume: 9 Issue: 45 Pages: 27645-27655
- DOI
  10.18632/oncotarget.25291
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09863
[Journal Article] サーチュイン阻害剤による白血病細胞のオートファジー2018
- Author(s)
  小迫知弘、鈴木孝禎
- Journal Title
  
  BIO Clinica
  
  Volume: 33 Pages: 68-73
- Data Source
  KAKENHI-PROJECT-16K09863
[Journal Article] Induction of apoptosis and autophagy by Nampt inhibition in adult T-cell leukemia/lymphoma and leukemic cell lines2016
- Author(s)
  Tomohiro Kozako, Makoto Yoshimitsu, Naomichi Arima, Keisuke Sato, Moe Toyoshima, Shin-ichiro Honda, Shinji Soeda
- Journal Title
  
  BLOOD
  
  Volume: 128 Pages: 2327-2327
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09863
[Journal Article] Angiotensin II type 1 receptor blocker telmisartan induces apoptosis and autophagy in adult T-cell leukemia cells2016
- Author(s)
  Tomohiro Kozako, Shuhei Soeda, Makoto Yoshimitsu, Naomichi Arima, Ayako Kuroki, Shinya Hirata, Hiroaki Tanaka, Osamu Imakyure, Nanako Tone, Shin-ichiro Honda, Shinji Soeda
- Journal Title
  
  FEBS Open Bio
  
  Volume: 6 Issue: 5 Pages: 442-460
- DOI
  10.1002/2211-5463.12055
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25242065, KAKENHI-PROJECT-16K09863
[Journal Article] Shedding by ADAM10 and ADAM17 is associated with progression of adult T-cell leukemia/lymphoma2015
- Author(s)
  Takemoto S, Kozako T, Pornkuna R.
- Journal Title
  
  Integrative Cancer Science and Therapeutics
  
  Volume: 2 Issue: 1 Pages: 79-81
- DOI
  10.15761/icst.1000118
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24591413
[Journal Article] Anticancer agents targeted to sirtuins.2014
- Author(s)
  Kozako T, Suzuki T, Yoshimitsu M, Arima N, Honda S, Soeda S.
- Journal Title
  
  Molecules
  
  Volume: 19 Issue: 12 Pages: 20295-313
- DOI
  10.3390/molecules191220295
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24591413
[Journal Article] Effects of exogenous interleukin-7 on CD8(+) T-cell survival and function in human T-cell lymphotropic virus type 1 infection.2013
- Author(s)
  White Y, Yoshimitsu M, Kozako T, Matsushita K, Koriyama C, Uozumi K, Suzuki S, Kofune H, Arima N.
- Journal Title
  
  Leukemia and Lymphoma.
  
  Volume: 54 Issue: 10 Pages: 2243-2250
- DOI
  10.3109/10428194.2013.772174
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300356, KAKENHI-PROJECT-23591398, KAKENHI-PROJECT-24591413
[Journal Article] Assessment of peripheral blood CD4+ adenosine triphosphate activity in patients with rheumatoid arthritis.2013
- Author(s)
  Akimoto M, Yunoue S, Otsubo H, Yoshitama T, Kodama K, Matsushita K, Suruga Y, Kozako T, Toji S, Hashimoto S, Uozumi K, Matsuda T, Arima N.
- Journal Title
  
  Mod Rheumatol.
  
  Volume: 23 Issue: 1 Pages: 19-27
- DOI
  10.1007/s10165-012-0621-1
- NAID
  10031167662
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591413
[Journal Article] Liposomes and nanotechnology in drug development: focus on oncotargets2012
- Author(s)
  Kozako T, Arima N, Yoshimitsu M, Honda S-I, Soeda S
- Journal Title
  
  International Journal of Nanomedicine
  
  Volume: 7 Pages: 4943-4951
- DOI
  10.2147/ijn.s30726
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591413
[Journal Article] High expression of the longevity gene product SIRT1 and apoptosis induction by sirtinol in adult T-cell leukemia cells2012
- Author(s)
  Kozako T.
- Journal Title
  
  Int J Cancer
  
  Volume: (In press) Issue: 9 Pages: 2044-2055
- DOI
  10.1002/ijc.27481
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390102, KAKENHI-PROJECT-24591413
[Journal Article] Vasohibin induces prolyl hydroxylase-mediated degradation of hypoxia-inducible factor-1α in human umbilical vein endothelial cells.2012
- Author(s)
  Kozako T, Matsumoto N, Kuramoto Y, Sakata A, Motonagare R, Aikawa A, Imoto M, Toda A, Honda S, Shimeno H, Soeda S.
- Journal Title
  
  FEBS Lett.
  
  Volume: 586 Issue: 7 Pages: 1067-1072
- DOI
  10.1016/j.febslet.2012.03.007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591413
[Journal Article] LIM-homeo domain transcription factor, Lhx2, is involved in transcriptional control of brain-specific promoter/exon 1f of the2012
- Author(s)
  Honda, S.-I., Kozako, T., Shimeno, H.
- Journal Title
  
  J Neuro
  
  Volume: 66(2) Issue: 11 Pages: 260-272
- DOI
  10.1111/j.1365-2826.2012.02356.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591019, KAKENHI-PROJECT-23591360, KAKENHI-PROJECT-24591413
[Journal Article] Target epitopes of HTLV-1 recognized by class I MHC-restricted cytotoxic T lymphocytes in patients with myelopathy and spastic paraparesis and infected patients with autoimmune disorders2011
- Author(s)
  Kozako T. Akimoto M, Toji S, (他11名, 1番目)
- Journal Title
  
  J. Med. Virology
  
  Volume: 83 Pages: 501-509
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790921
[Journal Article] Novel Cytotoxic Isolated from Jamaican Hyptis verticillata jacq Induces Apoptosis and Overcomes Multidrug Resistance2011
- Author(s)
  White Y, Hamada T, Yoshimitsu M, Nakashima M, Hachiman M, Kozako T, et al. White Y, Hamada T, Yoshimitsu M, Nakashima M, Hachiman M, Kozako T, et al.(他5名, 6番目)
- Journal Title
  
  Anticancer Res
  
  Volume: 12 Pages: 4251-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790921
[Journal Article] Novel Cytotoxic Isolated from Jamaican Hyptis verticillata jacq Induces Apoptosis and Overcomes Multidrug Resistance2011
- Author(s)
  White Y, Hamada T, Yoshimitsu M, Nakashima M, Hachiman M, Kozako T, et al
- Journal Title
  
  Anticancer Res
  
  Volume: 31 Pages: 4251-4257
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790921
[Journal Article] New Strategy of Adult T-cell Leukemia Treatment Targeted for Anti-tumor Immunity and a Longevity Gene-encoded Protein2011
- Author(s)
  Kozako T
- Journal Title
  
  Yakugaku Zasshi
  
  Volume: 131 Pages: 1061-1072
- NAID
  130000926995
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790921
[Journal Article] Oligomannose-coated liposomes efficiently induce human T-cell leukemia virus-1-specific cytotoxic T lymphocytes without adjuvant2011
- Author(s)
  Kozako I, Hirata S, et al
- Journal Title
  
  FEBS J
  
  Volume: 278 Pages: 1358-1366
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790921
[Journal Article] Oligomannose-coated liposomes efficiently induce human T-cell leukemia virus-1-specific cytotoxic T lymphocytes without adjuvant2011
- Author(s)
  Kozako T. Hirata S, Shimizu Y, Satoh Y, Yoshimitsu M, White Y, Lemonnier F, Shimeno H, Soeda S, Arima N
- Journal Title
  
  FEBS Journal
  
  Volume: 278 Pages: 1358-1366
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790921
[Journal Article] PD-1/PD-L1 Pathway-Mediated Immune Responses Against Human T-Lymphotropic Virus Type I in HAM/TSP and Carriers with Collagen Diseases2011
- Author(s)
  Kozako T, Yoshimitsu M, Akimoto M, (他7名, 1番目)
- Journal Title
  
  Human Immunology
  
  Volume: 72 Pages: 1001-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790921
[Journal Article] PD-1/PD-L1 Pathway-Mediated Immune Eesponses Against Human T-Lymphotropic Virus Type I in HAM/TSP and Carriers with Collagen Diseases2011
- Author(s)
  Kozako T, Yoshimitsu M, et al
- Journal Title
  
  Human Immunology
  
  Volume: 72 Pages: 1001-1006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790921
[Journal Article] Fasting promotes the expression of SIRT1, an NAD(+)-dependent protein deacetylase, via activation of PPARalpha in mice2010
- Author(s)
  Hayashida S, Arimoto A, Kuramoto Y, Kozako T, Honda SI, Shimeno H, Soeda S
- Journal Title
  
  Molecular Cell Biochemistry
  
  Volume: 339 Pages: 285-292
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790921
[Journal Article] Fasting promotes the expression of SIRT1, an NAD+-dependent protein deacetylase, via activation of PPARα in mice.2010
- Author(s)
  Hayashida S, Arimoto A, Kuramoto Y, Kozako T, et al.
- Journal Title
  
  Mol Cell Biochem.
  
  Volume: 339 Pages: 285-92
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790921
[Journal Article] Target epitopes of HTLV-1 recognized by class I MHC-restricted cytotoxic T lymphocytes in patients with myelopathy and spastic paraparesis and infected patients with autoimmune disorders.2010
- Author(s)
  Kozako T, Akimoto M, et al.
- Journal Title
  
  J Med Virol
  
  Volume: 83 Pages: 501-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790921
[Journal Article] PD-1/PD-L1 expression in HTLV-1 carriers and adult T-cell leukemia/lymphoma patients2009
- Author(s)
  Kozako T, et.al.
- Journal Title
  
  Leukemia 23
  
  Pages: 375-382
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790671
[Journal Article] PD-1/PD-L1 e xpression in HTLV-1 carriers and adult T-cell leuk emia/lymphoma patients.2009
- Author(s)
  Kozako T., Yoshimitsu M., et al.
- Journal Title
  
  Leukemia 23
  
  Pages: 75-382
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790671
[Journal Article] CTL exhaustion in persistent HTLV-1 infection and ATLL is rest ored through PD-1/PD-L1 pathwa2008
- Author(s)
  Kozako T., Yoshimitsu M., et al.
- Journal Title
  
  Blood 110
  
  Pages: 511-511
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790671
[Journal Article] Anti-apoptotic roles of PAI-1 as a neurotrophic factor in the central nervous system.2008
- Author(s)
  Soeda S., Koyanagi S., Yukako K., KozakoT., et al.
- Journal Title
  
  Thrombosis and Haemostasis 100
  
  Pages: 1014-1020
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790671
[Journal Article] Anti-HTLV-1 Tax antibody and Tax-specific cytotoxic T lymphocyte are associated with a reduction in HTLV-1 proviral load in asymptomatic carriers2007
- Author(s)
  Akimoto M, Kozako T, et. al.
- Journal Title
  
  Journal of Medical Virology 79
  
  Pages: 977-986
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790671
[Journal Article] CTL exhaustion in persistent HTLV-1 infection and ATLL is restored through PD-1/PD-L1 pathway2007
- Author(s)
  Kozako T, et. al.
- Journal Title
  
  Blood 110
  
  Pages: 511-511
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790671
[Journal Article] Anti-HTLV-1 Taxantibody and Tax-specific cytotoxic T lymphocyte are associated with a reduction in HTLV-1 proviral load in asymptomatic carriers.2007
- Author(s)
  Akimoto M, Kozako T, et al.
- Journal Title
  
  Journal of Medical Virology 79
  
  Pages: 977-986
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790671
[Presentation] 細胞毒性試験を用いたシクロホスファミドの職業性曝露対策に向けたエビデンスの構築2025
- Author(s)
  上田裕、中野貴文、小迫知弘、佐藤朝光、大薮康平、真島宏太、眞崎晃、角康隆、吹上勇真、宮崎元康、今給黎修、緒方憲太郎
- Organizer
  第14回日本臨床腫瘍薬学会学術大会（横浜）
- Data Source
  KAKENHI-PROJECT-22K08491
[Presentation] HDAC8を標的としたPROTAC化合物による成人T細胞白血病細胞株の細胞死2024
- Author(s)
  西仲間翔和、小迫知弘、徳永彩華、加藤奈歩、伊藤幸裕、鈴木孝禎、本田伸一郎
- Organizer
  日本薬学会第144年会（横浜）
- Data Source
  KAKENHI-PROJECT-22K08491
[Presentation] HDAC8を標的としたPROTAC化合物によるATL関連細胞株の細胞死に対する影響2024
- Author(s)
  西中間翔和、小迫知弘、徳永彩華、加藤奈歩、伊藤幸裕、鈴木孝禎、本田伸一郎
- Organizer
  第10回日本HTLV-1学会学術集会（東京）
- Data Source
  KAKENHI-PROJECT-22K08491
[Presentation] LAT1阻害剤によるATL関連細胞株に対する細胞増殖抑制誘導機構の検討2024
- Author(s)
  加藤奈歩、小迫知弘、本田伸一郎、古賀鈴依子、吉田秀幸、能田均
- Organizer
  第10回日本HTLV-1学会学術集会（東京）
- Data Source
  KAKENHI-PROJECT-22K08491
[Presentation] 成人T細胞白血病におけるアポトーシスおよびネクロプトーシスを介したAICARの抗腫瘍効果2024
- Author(s)
  加藤奈歩、相川晃慶、小迫知弘、大杉剛生、本田伸一郎
- Organizer
  日本薬学会第144年会（横浜）
- Data Source
  KAKENHI-PROJECT-22K08491
[Presentation] ATLにおけるアポトーシスおよびオートファジーを介するCDK9阻害剤の抗腫瘍効果2023
- Author(s)
  加藤奈歩、小迫知弘、大杉剛生、内田友一朗、吉満誠、石塚賢治、相川晃慶、本田伸一郎
- Organizer
  第9回日本HTLV-1学会学術集会（京都）
- Data Source
  KAKENHI-PROJECT-22K08491
[Presentation] 成人T細胞白血病細胞株におけるBrentuximab Vedotinによる細胞死に対する細胞外CD30とADAM10/17の影響2023
- Author(s)
  佐藤啓介、小迫知弘、中野陽、緒方憲太郎、佐々木秀法、高松泰、武本重毅、神村英利、本田伸一郎
- Organizer
  第9回日本HTLV-1学会学術集会（京都）
- Data Source
  KAKENHI-PROJECT-22K08491
[Presentation] 成人T細胞白血病細胞におけるCD30の切断と抗CD30抗体薬の効果に対するADAM10/17の影響2023
- Author(s)
  中野　陽、小迫　知弘、佐藤　啓介、田中　めぐ美、讃井　美保、加藤　奈歩、本田　伸一郎
- Organizer
  日本薬学会第143年会（札幌）
- Data Source
  KAKENHI-PROJECT-22K08491
[Presentation] Anti-tumor activity of AICAR via AMPK-independent cell death in adult T-cell leukemia/lymphoma2023
- Author(s)
  小迫知弘、相川晃慶、大杉剛生、本田伸一郎
- Organizer
  第96回日本生化学会大会（福岡）
- Data Source
  KAKENHI-PROJECT-22K08491
[Presentation] 成人T細胞白血病におけるCDK9阻害剤による抗腫瘍効果の検討2023
- Author(s)
  加藤　奈歩、小迫　知弘、大杉　剛生、内田　友一朗、吉満　誠、石塚　賢治、相川　晃慶、本田　伸一郎
- Organizer
  日本薬学会第143年会（札幌）
- Data Source
  KAKENHI-PROJECT-22K08491
[Presentation] 成人T細胞白血病関連細胞株の細胞死に対するCDK9阻害剤の影響2022
- Author(s)
  加藤　奈歩、小迫　知弘、大杉　剛生、相川　晃慶、本田　伸一郎
- Organizer
  日本薬学会第142年会（名古屋、Web開催）
- Data Source
  KAKENHI-PROJECT-19K08851
[Presentation] SIRT1活性化剤SRT1720の成人T細胞白血病（ATL）細胞株に対する腫瘍抑制効果2021
- Author(s)
  飯沼海仁、猪狩陽希、橋本祐樹、加藤　奈歩、佐藤　陽菜、相川　晃慶、小迫知弘、本田　伸一郎、大杉剛生
- Organizer
  第68回日本実験動物学会総会（さいたま市）
- Data Source
  KAKENHI-PROJECT-19K08851
[Presentation] SRT1720による成人T細胞白血病細胞株の細胞死に関する検討2021
- Author(s)
  小迫　知弘
- Organizer
  第80回日本癌学会学術総会（横浜）
- Data Source
  KAKENHI-PROJECT-19K08851
[Presentation] AICARによるヒトT細胞白血病ウイルス1型感染細胞株の細胞死誘導機序2021
- Author(s)
  相川晃慶、山崎七恵、堀ノ内好香、小迫知弘、佐藤陽菜、大杉剛生、本田伸一郎
- Organizer
  日本薬学会第141年会（広島、Web開催）
- Data Source
  KAKENHI-PROJECT-19K08851
[Presentation] DorsomorphinによるヒトT細胞白血病1型感染細胞株のアポトーシス誘導2020
- Author(s)
  相川晃慶、小迫知弘、内田友一朗、吉満誠、大杉剛生、副田二三男、戸田晶久、本田伸一郎
- Organizer
  日本薬学会第140年会（京都）
- Data Source
  KAKENHI-PROJECT-19K08851
[Presentation] SRT1720による成人T細胞白血病細胞株の細胞死2020
- Author(s)
  竹内　薫、小迫　知弘、佐藤　陽菜、相川　晃慶、本田　伸一郎
- Organizer
  日本薬学会第140年会（京都）
- Data Source
  KAKENHI-PROJECT-19K08851
[Presentation] 成人T細胞白血病におけるSRT1720の抗腫瘍効果2020
- Author(s)
  小迫　知弘、加藤奈歩、大杉剛生、相川　晃慶、佐藤　陽菜、本田　伸一郎
- Organizer
  第43回日本分子生物学会年会（神戸、Web開催）
- Data Source
  KAKENHI-PROJECT-19K08851
[Presentation] AICARによる成人T細胞白血病細胞株のアポトーシス誘導2020
- Author(s)
  山崎七恵、相川晃慶、小迫知弘、　大杉剛生、本田伸一郎
- Organizer
  日本薬学会第140年会（京都）
- Data Source
  KAKENHI-PROJECT-19K08851
[Presentation] 成人T細胞白血病（adult T-cell leukemia:ATL）由来細胞株に対する AMPK阻害剤Dorsomorphinの効果2019
- Author(s)
  横山智也、相川晃慶、小迫知弘、大杉剛生
- Organizer
  北海道実験動物研究会（北海道）
- Data Source
  KAKENHI-PROJECT-19K08851
[Presentation] High NAMPT expression and anti-tumor activity of NAMPT inhibitor in adult T-cell leukemia/lymphoma2019
- Author(s)
  Tomohiro Kozako, Takeo Ohsugi, Yu-ichiro Uchida, Makoto Yoshimitsu, Kenji Ishitsuka, Naho Kato, Keisuke Sato, Akiyoshi Aikawa, and Shin-ichiro Honda
- Organizer
  ESMO 2019 Congress (Barcelona, Spain)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08851
[Presentation] AICARを用いた新規成人T細胞白血病治療法の検討2019
- Author(s)
  相川晃慶、小迫知弘、吉満誠、大杉剛生、本田　伸一郎
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-16K09863
[Presentation] Brentuximab vedotinによる細胞死に対する可溶性CD30とADAM10/17の影響2019
- Author(s)
  佐藤啓介、小迫知弘、田中めぐ美、讃井美保、相川晃慶、武本重毅、本田伸一郎
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-16K09863
[Presentation] NAMPT阻害剤による成人T細胞白血病細胞における抗腫瘍効果の検討2019
- Author(s)
  加藤奈歩、小迫知弘、大杉剛生、内田友一朗、吉満誠、石塚賢治、佐藤啓介、相川晃慶、本田伸一郎
- Organizer
  第6回日本HTLV-1学会学術集会（宮崎）
- Data Source
  KAKENHI-PROJECT-19K08851
[Presentation] AICARによるHTLV-1感染細胞株の細胞死誘導機序についての検討2019
- Author(s)
  山崎七恵、相川晃慶、小迫知弘、　大杉剛生、本田伸一郎
- Organizer
  第6回日本HTLV-1学会学術集会（宮崎）
- Data Source
  KAKENHI-PROJECT-19K08851
[Presentation] Brentuximab vedotinによる細胞死に対する可溶性CD30とADAM10/17の影響2019
- Author(s)
  佐藤啓介、小迫知弘、緒方憲太郎、神村英利、佐々木秀法、高松泰、武本重毅、本田伸一郎
- Organizer
  第6回日本HTLV-1学会学術集会（宮崎）
- Data Source
  KAKENHI-PROJECT-19K08851
[Presentation] AICARによるHTLV-1感染細胞株のアポトーシス性細胞死誘導機序についての検討2019
- Author(s)
  山崎七恵、相川晃慶、小迫知弘、　大杉剛生、本田伸一郎
- Organizer
  第42回日本分子生物学会年会(福岡）
- Data Source
  KAKENHI-PROJECT-19K08851
[Presentation] AICARまたはMetforminによるHTLV-1感染細胞株の細胞死誘導機序の検討2018
- Author(s)
  相川晃慶、小迫知弘、吉満誠、有馬直道、本田伸一郎
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-16K09863
[Presentation] Brentuximab vedotinによる細胞死に対する可溶性CD30の影響2018
- Author(s)
  田中めぐ美、小迫知弘、讃井美保、佐藤啓介、相川晃慶、本田伸一郎、武本重毅
- Organizer
  第5回日本HTLV-1学会学術集会
- Data Source
  KAKENHI-PROJECT-16K09863
[Presentation] Dorsomorphinはヒト成人T細胞白血病ウイルス1型感染細胞株のアポトーシスを誘導する2018
- Author(s)
  相川晃慶、小迫知弘、吉満誠、本田伸一郎
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16K09863
[Presentation] Overexpression of NAMPT in adult T-cell leukemia/lymphoma patients and antitumor activity of a NAMPT inhibitor in vivo2018
- Author(s)
  Tomohiro Kozako, Takeo Ohsugi, Makoto Yoshimitsu, Yu-ichiro Uchida, Kenji Ishitsuka, Naho Kato, Akiyoshi Aikawa, and Shin-ichiro Honda
- Organizer
  ESMO 2018 Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09863
[Presentation] 成人T細胞白血病細胞におけるNAMPT阻害剤による細胞死の検討2018
- Author(s)
  加藤奈歩、小迫知弘、大杉剛生、吉満誠、内田友一朗、石塚賢治、相川晃慶、本田伸一郎
- Organizer
  第5回日本HTLV-1学会学術集会
- Data Source
  KAKENHI-PROJECT-16K09863
[Presentation] STF-62247による白血病細胞株の細胞死に対する検討2017
- Author(s)
  佐藤啓介、小迫知弘、豊島萌恵、今石果奈、伊藤文人、緒方憲太郎、神村英利、本田伸一郎
- Organizer
  第4回日本HTLV-1学会学術集会
- Data Source
  KAKENHI-PROJECT-16K09863
[Presentation] 成人T細胞白血病ウイルス1型感染細胞株におけるDorsomorphin誘導性アポトーシスの作用機序2017
- Author(s)
  相川晃慶、小迫知弘、福田梓、吉満誠、有馬直道、本田伸一郎
- Organizer
  第40回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16K09863
[Presentation] STF-62247による胞白血病細胞株の細胞死に対する検討2017
- Author(s)
  佐藤啓介、小迫知弘、今石果奈、豊島萌恵、相川晃慶、本田伸一郎、添田秦司
- Organizer
  日本薬学会第137回
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-16K09863
[Presentation] Angiotensin II type 1 receptor blocker induces apoptosis and autophagy in adult T-cell leukemia cells2017
- Author(s)
  Tomohiro Kozako, Shuhei Soeda, Makoto Yoshimitsu, Naomichi Arima, Ayako Kuroki, Hiroaki Tanaka, Shinya Hirata, Shin-ichiro Honda, and Shinji Soeda
- Organizer
  18th International Conference on Human Retrovirology HTLV and Related Viruses
- Place of Presentation
  Tokyo
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09863
[Presentation] ARP1と相互作用するタンパク質の解析2017
- Author(s)
  本田伸一郎、小迫知弘、相川晃慶、原田信広
- Organizer
  第40回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16K09863
[Presentation] HTLV-1感染細胞株における可溶性CD30産生に対するADAMファミリーの関与2017
- Author(s)
  讃井美保、小迫知弘、野田圭吾、相川晃慶、本田伸一郎、武本重毅
- Organizer
  第4回日本HTLV-1学会学術集会
- Data Source
  KAKENHI-PROJECT-16K09863
[Presentation] STF-62247によるアポトーシスおよびオートファジーを介する細胞死に関する検討2017
- Author(s)
  小迫知弘、佐藤啓介、緒方憲太郎、神村英利
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K09863
[Presentation] 新規SIRT2阻害剤による成人T細胞白血病細胞株の細胞死に対する検討2017
- Author(s)
  岡里佐子、小迫知弘、今石果奈、鈴木孝禎、Paolo Mellini、吉満誠、有馬直道、相川晃慶、本田伸一郎
- Organizer
  第4回日本HTLV-1学会学術集会
- Data Source
  KAKENHI-PROJECT-16K09863
[Presentation] 高齢者への多剤投与ががん化学療法に影響を及ぼす因子に関する後方視的探索研究2017
- Author(s)
  緒方憲太郎、田村和夫、佐藤啓介、佐藤陽菜、内山将伸、清見文明、安高勇気、小迫知弘、髙松泰、兼重晋、神村英利
- Organizer
  日本がんサポーティブケア学会
- Data Source
  KAKENHI-PROJECT-16K09863
[Presentation] Dorsomorphinを用いた新規成人T細胞白血病治療法の検討2017
- Author(s)
  相川　晃慶、小迫　知弘、福田　梓、吉満　誠、有馬　直道、本田　伸一郎、添田　秦司
- Organizer
  日本薬学会第137回
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-16K09863
[Presentation] 成人T細胞白血病における可溶性CD30産生に対するADAMファミリーの関与2016
- Author(s)
  野田　圭吾、小迫　知弘、西岡千恵、ポルンクナ　ラティオン、河野　文夫、武本　重毅
- Organizer
  第3回日本HTLV-1学会学術集会
- Place of Presentation
  鹿児島
- Data Source
  KAKENHI-PROJECT-16K09863
[Presentation] ニコチンアミドホスホリボシル基転移酵素を標的とした成人T細胞白血病治療の可能性2016
- Author(s)
  豊島　萌恵、小迫　知弘、吉満　誠、有馬　直道、相川　晃慶、佐藤　啓介、本田　伸一郎、添田　秦司
- Organizer
  第3回日本HTLV-1学会学術集会
- Place of Presentation
  鹿児島
- Data Source
  KAKENHI-PROJECT-16K09863
[Presentation] 可溶性CD25ならびにCD30血清レベル上昇から示唆された成人T細胞白血病病態形成に関わる酵素活性2016
- Author(s)
  武本　重毅，小迫　知弘，日高　道弘，河野　文夫
- Organizer
  第56回日本リンパ網内系学会総会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-16K09863
[Presentation] Compound Cを用いたHTLV-1感染細胞株のアポトーシス誘導機序の検討2016
- Author(s)
  福田梓、相川晃慶、小迫知弘、吉満誠、有馬直道、本田伸一郎、添田秦司
- Organizer
  第3回日本HTLV-1学会学術集会
- Place of Presentation
  鹿児島
- Data Source
  KAKENHI-PROJECT-16K09863
[Presentation] DorsomorphinによるHTLV-1感染細胞株のアポトーシス誘導2016
- Author(s)
  相川　晃慶、小迫　知弘、福田　梓、吉満　誠、有馬　直道、本田　伸一郎、添田　秦司
- Organizer
  第33回日本薬学会九州支部大会
- Place of Presentation
  鹿児島
- Data Source
  KAKENHI-PROJECT-16K09863
[Presentation] 新規SIRT2阻害剤による白血病細胞株の細胞死に対する検討2016
- Author(s)
  今石果奈、小迫知弘、吉満誠、有馬直道、鈴木孝禎、大坪菜々子、相川晃慶、本田伸一郎、添田秦司
- Organizer
  第3回日本HTLV-1学会学術集会
- Place of Presentation
  鹿児島
- Data Source
  KAKENHI-PROJECT-16K09863
[Presentation] Our view of high serum levels of soluble CD30 associated with clinical lesions in adult T-cell leukemia2016
- Author(s)
  武本　重毅，小迫　知弘
- Organizer
  第45回日本免疫学会学術集会
- Place of Presentation
  沖縄
- Data Source
  KAKENHI-PROJECT-16K09863
[Presentation] テルミサルタンによる白血病細胞の細胞死に関する検討2016
- Author(s)
  小迫知弘
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-16K09863
[Presentation] Induction of apoptosis and autophagy by Nampt inhibition in adult T-cell leukemia/lymphoma and leukemic cell lines2016
- Author(s)
  Tomohiro Kozako, Makoto Yoshimitsu, Naomichi Arima, Keisuke Sato, Moe Toyoshima, Shin-ichiro Honda, Shinji Soeda
- Organizer
  The American Society of Hematology 58th Annual Meeting
- Place of Presentation
  SanDiego, CA
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09863
[Presentation] 脳特異的アロマターゼプロモーターの活性に及すDeaf1のSUMO化の影響2014
- Author(s)
  本田伸一郎、小迫知弘、相川晃慶、坂田晃、原田信広、添田秦司
- Organizer
  第３７回日本分子生物学会年会
- Place of Presentation
  横浜市
- Year and Date
  2014-11-27
- Data Source
  KAKENHI-PROJECT-24591413
[Presentation] 新規SIRT1阻害剤による成人T細胞白血病細胞の増殖抑制効果に関する検討2014
- Author(s)
  小迫知弘、有馬直道
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  横浜市
- Year and Date
  2014-09-25
- Data Source
  KAKENHI-PROJECT-24591413
[Presentation] SIRT1を標的とした成人T細胞白血病治療法に関する検討2014
- Author(s)
  小迫　知弘、馬島　礼、鈴木　孝禎、吉満　誠、相川　晃慶、本田　伸一郎、有馬　直道、添田　秦司
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-24591413
[Presentation] 成人T細胞白血病におけるAMP活性化プロテインキナーゼ標的薬による抗腫瘍効果2014
- Author(s)
  相川　晃慶、小迫　知弘、横松　恵里佳、吉満　誠、有馬　直道、本田　伸一郎、添田　秦司
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-24591413
[Presentation] 新規SIRT1阻害剤による白血病細胞の細胞死に関する検討2014
- Author(s)
  内田　友一朗、小迫　知弘、鈴木　孝禎、馬島　礼、相川　晃慶、本田　伸一郎、吉満　誠⁾、有馬　直道、添田　秦司
- Organizer
  第1回日本HTLV-1学会学術集会
- Place of Presentation
  東京都
- Year and Date
  2014-08-23
- Data Source
  KAKENHI-PROJECT-24591413
[Presentation] Compound C、AICARおよびMetforminによるHTLV-1感染細胞株の増殖抑制効果2014
- Author(s)
  相川　晃慶、小迫　知弘、横松　恵里佳、吉満　誠、有馬　直道、坂田　晃、本田　伸一郎、添田　秦司
- Organizer
  第31回日本薬学会九州支部会
- Place of Presentation
  福岡市
- Year and Date
  2014-12-06
- Data Source
  KAKENHI-PROJECT-24591413
[Presentation] Compound C, AICARおよびMetforminはAMPKを介さずにHTLV-1感染細胞株の増殖抑制作用を示す2014
- Author(s)
  相川　晃慶、小迫　知弘、横松　恵里佳、吉満　誠、有馬　直道、坂田　晃、本田　伸一郎、添田　秦司
- Organizer
  第1回日本HTLV-1学会学術集会
- Place of Presentation
  東京都
- Year and Date
  2014-08-23
- Data Source
  KAKENHI-PROJECT-24591413
[Presentation] アロマターゼの脳特異的プロモーターに存在するシスエレメント、AIIサイトに結合する転写因子の解析2014
- Author(s)
  山口貴広、本田伸一郎、小迫知弘、相川晃慶、坂田晃、原田信広、添田秦司
- Organizer
  第31回日本薬学会九州支部会
- Place of Presentation
  福岡市
- Year and Date
  2014-12-06
- Data Source
  KAKENHI-PROJECT-24591413
[Presentation] Deaf1タンパク質の機能ドメインの解析2014
- Author(s)
  本田伸一郎,原田信広、小迫知弘,相川晃慶,坂田晃1,添田秦司
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-24591413
[Presentation] AMPKを標的とした薬剤を用いた新規成人T細胞白血病治療法の検討2013
- Author(s)
  相川　晃慶、小迫　知弘、横松　恵里佳、吉満　誠、有馬　直道、本田　伸一郎、添田　秦司
- Organizer
  第30回日本薬学会九州支部大会
- Place of Presentation
  佐世保市
- Data Source
  KAKENHI-PROJECT-24591413
[Presentation] AMPK活性剤による新規成人T細胞白血病治療法の検討2013
- Author(s)
  横松恵里佳、相川晃慶、小迫　知弘、本田　伸一郎、吉満　誠、魚住　公治有馬　直道、添田　秦司
- Organizer
  第6回HTLV-1研究会（東京都）
- Place of Presentation
  東京都
- Data Source
  KAKENHI-PROJECT-24591413
[Presentation] A novel SIRT1 inhibitor induces apoptosis in leukemic cell lines2013
- Author(s)
  小迫知弘、有馬直道
- Organizer
  第72回日本癌学会総会
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-24591413
[Presentation] 新規SIRT1阻害剤による白血病細胞の増殖抑制効果に関する検討2013
- Author(s)
  馬島　礼、小迫　知弘、鈴木　孝禎、相川晃慶、本田　伸一郎、吉満　誠、有馬　直道、添田　秦司
- Organizer
  第6回HTLV-1研究会
- Place of Presentation
  東京都
- Data Source
  KAKENHI-PROJECT-24591413
[Presentation] エネルギー代謝因子を標的とした成人T細胞白血病治療法の検討2012
- Author(s)
  蒲原裕典、小迫知弘、相川晃慶、吉満誠、有馬直道、田中宏暁、本田伸一郎、添田秦司
- Organizer
  日本生化学会九州支部例会
- Place of Presentation
  福岡市
- Data Source
  KAKENHI-PROJECT-24591413
[Presentation] オリゴマンノース被覆リポソームによる効率的なHTLV-1特異的細胞障害性T細胞の誘導2012
- Author(s)
  小迫知弘、平田真哉
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌市
- Year and Date
  2012-03-30
- Data Source
  KAKENHI-PROJECT-22790921
[Presentation] エネルギー代謝因子AMPKを標的とした新規成人T細胞白血病治療法の検討2012
- Author(s)
  相川晃慶、小迫知弘、蒲原裕典、吉満誠、魚住公治、有馬直道、本田伸一郎、添田秦司
- Organizer
  第5回HTLV-1研究会
- Place of Presentation
  東京都
- Data Source
  KAKENHI-PROJECT-24591413
[Presentation] SIRT1活性化剤による白血病細胞の増殖抑制効果に関する検討2012
- Author(s)
  植村陽菜、小迫知弘、有馬直道、田中宏暁、本田伸一郎、添田秦司
- Organizer
  第5回HTLV-1研究会
- Place of Presentation
  東京都
- Data Source
  KAKENHI-PROJECT-24591413
[Presentation] アロマターゼの脳特異的発現に関与する転写因子Deaf-12012
- Author(s)
  本田伸一郎、大下遥子、民本愛、小迫知弘、蔵元佑嘉子,元流梨恵、原田信広、添田秦司
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡市
- Data Source
  KAKENHI-PROJECT-24591413
[Presentation] オリゴマンノース被覆リポソームワクチンによるHTLV-1特異的CTLの誘導2011
- Author(s)
  小迫知弘、平田真哉
- Organizer
  第3回造血器腫瘍免疫療法研究会
- Place of Presentation
  別府市
- Year and Date
  2011-08-20
- Data Source
  KAKENHI-PROJECT-22790921
[Presentation] 発生工学的手法を用いた脳内アロマターゼの機能解析2011
- Author(s)
  民本愛、本田伸一郎、小迫知弘
- Organizer
  第39回薬学活性シンポジウム
- Place of Presentation
  福岡市
- Year and Date
  2011-11-21
- Data Source
  KAKENHI-PROJECT-22790921
[Presentation] アロマターゼの脳特異的プロモーター結合因子の解析2011
- Author(s)
  大下遥子、本田伸一郎、小迫知弘
- Organizer
  第39回薬学活性シンポジウム
- Place of Presentation
  福岡市
- Year and Date
  2011-11-21
- Data Source
  KAKENHI-PROJECT-22790921
[Presentation] SIRT1を標的とした創薬の成人T細胞白血病治療法に対する検討2011
- Author(s)
  久保光範、小迫知弘
- Organizer
  第4回HTLV-1研究会
- Place of Presentation
  東京都
- Year and Date
  2011-09-18
- Data Source
  KAKENHI-PROJECT-22790921
[Presentation] Overexpression of SIRT1 and induction of apoptosis by its inhibition in adult T-cell leukemia cells 15th International Conference of Human Retrovivology2011
- Author(s)
  Tomohiro Kozako, et al
- Organizer
  HTLV
- Place of Presentation
  Leuven, Belgium
- Year and Date
  2011-06-05
- Data Source
  KAKENHI-PROJECT-22790921
[Presentation] SIRT1を標的とした創薬による新規成人T細胞白血病治療法の開発2011
- Author(s)
  糸永昇平、小迫知弘
- Organizer
  第39回薬学活性シンポジウム
- Place of Presentation
  福岡市
- Year and Date
  2011-11-21
- Data Source
  KAKENHI-PROJECT-22790921
[Presentation] サフラン成分クロシンによるレドックス制御2011
- Author(s)
  中山利香、本田伸一郎、小迫知弘
- Organizer
  第28回日本薬学会九州支部大会
- Place of Presentation
  福岡市
- Year and Date
  2011-12-10
- Data Source
  KAKENHI-PROJECT-22790921
[Presentation] 新規SIRT1阻害剤による成人T細胞白血病治療法の開発2011
- Author(s)
  前村由佳、小迫知弘
- Organizer
  日本生化学会九州支部例会
- Place of Presentation
  久留米市
- Year and Date
  2011-05-21
- Data Source
  KAKENHI-PROJECT-22790921
[Presentation] Overexpression of SIRT1 and induction of apoptosis by its inhibition in adult T-cell leukemia cells2011
- Author(s)
  Tomohiro Kozako, et al
- Organizer
  15th International Conference of Human Retrovivology ; HTLV
- Place of Presentation
  Leuven, Belugium
- Year and Date
  2011-06-05
- Data Source
  KAKENHI-PROJECT-22790921
[Presentation] 成人T細胞白血病発症予防と治療をめざして～抗腫瘍免疫と抗老化分子に注目して～2011
- Author(s)
  小迫知弘、有馬直道、占野廣司、添田秦司
- Organizer
  第39回薬学活性シンポジウム
- Place of Presentation
  福岡市
- Year and Date
  2011-11-21
- Data Source
  KAKENHI-PROJECT-22790921
[Presentation] 抗腫瘍活性を持つ天然物の血管内皮細胞増殖因子(VEGF)発現に及ぼす影響2011
- Author(s)
  瓜生健太郎、藏元佑嘉子、小迫知弘
- Organizer
  日本生化学会九州支部例会
- Place of Presentation
  久留米市
- Year and Date
  2011-05-21
- Data Source
  KAKENHI-PROJECT-22790921
[Presentation] サフラン成分クロシンの神経細胞死抑制効果2011
- Author(s)
  中山利香、本田伸一郎、小迫知弘
- Organizer
  第19回ステロイドホルモン学会
- Place of Presentation
  福岡市
- Year and Date
  2011-11-26
- Data Source
  KAKENHI-PROJECT-22790921
[Presentation] 成人T細胞白血病発症予防と治療をめざして～抗腫瘍免疫と抗老化分子に注目して～2011
- Author(s)
  小迫知弘、有馬直道、占野廣司、添田秦司
- Organizer
  第39回薬学活性シンポジウム
- Place of Presentation
  福岡市(招待講演)
- Year and Date
  2011-11-21
- Data Source
  KAKENHI-PROJECT-22790921
[Presentation] マリンバイオ創出シーズの長寿遺伝子制御による生活習慣病予防の可能性2011
- Author(s)
  小迫知弘
- Organizer
  第4回薬学研究フォーラム
- Place of Presentation
  東京都
- Year and Date
  2011-01-07
- Data Source
  KAKENHI-PROJECT-22790921
[Presentation] 脳特異的なアロマターゼ発現に関与するDeaf-1タンパク質の機能解析2011
- Author(s)
  原口美紀、古田展也、安田千穂、本田伸一郎、小迫知弘
- Organizer
  日本生化学会九州支部例会
- Place of Presentation
  久留米市
- Year and Date
  2011-05-21
- Data Source
  KAKENHI-PROJECT-22790921
[Presentation] エネルギー代謝因子をターゲットとした新規白血病治療法の開発2011
- Author(s)
  賀茂奈保子、小迫知弘
- Organizer
  日本生化学会九州支部例会
- Place of Presentation
  久留米市
- Year and Date
  2011-05-21
- Data Source
  KAKENHI-PROJECT-22790921
[Presentation] 抗腫瘍活性を持つ天然物の血管内皮細胞(HUVEC)増殖に及ぼす影響2011
- Author(s)
  坪根未歩、藏元佑嘉子、小迫知弘
- Organizer
  日本生化学会九州支部例会
- Place of Presentation
  久留米市
- Year and Date
  2011-05-21
- Data Source
  KAKENHI-PROJECT-22790921
[Presentation] 長寿遺伝子SIRT1を標的とした新規白血病治療法の開発2011
- Author(s)
  久保光範、小迫知弘
- Organizer
  第28回日本薬学会九州支部大会
- Place of Presentation
  福岡市
- Year and Date
  2011-12-10
- Data Source
  KAKENHI-PROJECT-22790921
[Presentation] HTLV-1感染者におけるHTLV-1特異的CTLの発現の多様性2010
- Author(s)
  小迫知弘、吉満誠
- Organizer
  第3回HTLV-1研究会
- Place of Presentation
  東京都
- Year and Date
  2010-08-28
- Data Source
  KAKENHI-PROJECT-22790921
[Presentation] ATL関連細胞株における長寿遺伝子SIRT1の阻害剤によるアポトーシスの誘導2010
- Author(s)
  折田聡一、小迫知弘
- Organizer
  日本生化学会九州支部例会
- Place of Presentation
  鹿児島市
- Year and Date
  2010-05-22
- Data Source
  KAKENHI-PROJECT-22790921
[Presentation] Differences in high molecular weight adiponectin and adiponectin receptor alterations based on exercise and diet.2010
- Author(s)
  Tobina T, Nakashima H, Kozako T, et al.
- Organizer
  Integrative Physiology of Exercise
- Place of Presentation
  Miami, Florida
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-22790921
[Presentation] ガンの予防および治療における民間伝承植物の効果検討2010
- Author(s)
  今村翔、藏元佑嘉子、小迫知弘
- Organizer
  第27回日本薬学会九州支部大会
- Place of Presentation
  長崎市
- Year and Date
  2010-12-12
- Data Source
  KAKENHI-PROJECT-22790921
[Presentation] 転写因子Deaf-1の転写制御メカニズムの解析2010
- Author(s)
  安田千穂、本田伸一郎、小迫知弘
- Organizer
  第27回日本薬学会九州支部大会
- Place of Presentation
  長崎市
- Year and Date
  2010-12-12
- Data Source
  KAKENHI-PROJECT-22790921
[Presentation] SIRT1を標的としたATLの新規治療法の開発2010
- Author(s)
  小迫知弘、占野廣司、有馬直道
- Organizer
  第69回日本癌学会総会
- Place of Presentation
  大阪市
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-22790921
[Presentation] 宿主抗腫瘍免疫と長寿遺伝子を標的とした成人T細胞白血病治療法の開発2010
- Author(s)
  小迫知弘
- Organizer
  第27回日本薬学会九州支部大会
- Place of Presentation
  長崎市
- Year and Date
  2010-12-12
- Data Source
  KAKENHI-PROJECT-22790921
[Presentation] CD70 Expression on HTLV-1 Infected T Cells of Carriers and ATL Patients and Its Clinical Significance.2010
- Author(s)
  Masamoto I, Horai S, Kozako T, et al.
- Organizer
  The American Society of Hematology 52th Annual Meeting
- Place of Presentation
  Orland, Florida
- Year and Date
  2010-12-04
- Data Source
  KAKENHI-PROJECT-22790921
[Presentation] CD70 Expression on HTLV-1 Infected T Cells of Carriers and ATL Patients and Its Clinical Significance2010
- Author(s)
  Masamoto I, Horai S, Kozako T, et al.
- Organizer
  The American Society of Hematology 52th Annual Meeting
- Place of Presentation
  Orland, Florida
- Year and Date
  2010-12-04
- Data Source
  KAKENHI-PROJECT-22790921
[Presentation] HTLU-1感染者におけるHTLU-1特異的CTLの発現の多様性2010
- Author(s)
  小迫知弘、吉満誠, ら
- Organizer
  第3回HTLV-1研究会
- Place of Presentation
  東京都
- Year and Date
  2010-08-28
- Data Source
  KAKENHI-PROJECT-22790921
[Presentation] 民間伝承植物を用いたガン治療及び予防効果の検討2010
- Author(s)
  今村翔、藏元佑嘉子、小迫知弘
- Organizer
  日本生薬学会第57回年会・第5回日中韓生薬学合同シンポジウム
- Place of Presentation
  徳島市
- Year and Date
  2010-09-25
- Data Source
  KAKENHI-PROJECT-22790921
[Presentation] Overexpression of SIRT1, a Longevity Gene-Encoded Protein, and Induction of Apoptosis by Its Inhibition In Adult T-Cell Leukemia Cells.2010
- Author(s)
  Kozako T, et al.
- Organizer
  The American Society of Hematology 52th Annual Meeting
- Place of Presentation
  Orland, Florida
- Year and Date
  2010-12-04
- Data Source
  KAKENHI-PROJECT-22790921
[Presentation] アロマターゼの脳特異的プロモーターに作用する転写因子Deaf-1の機能ドメインの解析2010
- Author(s)
  安田千穂、本田伸一郎、小迫知弘
- Organizer
  日本ステロイドホルモン学会
- Place of Presentation
  名古屋
- Year and Date
  2010-11-27
- Data Source
  KAKENHI-PROJECT-22790921
[Presentation] Overexpression of SIRT1, a Longevity Gene-Encoded Protein, and Induction of Apoptosis by Its Inhibition In Adult T-Cell Leukemia Cells2010
- Author(s)
  Kozako T, et al.
- Organizer
  The American Society of Hematology 52th Annual Meeting
- Place of Presentation
  Orland, Florida
- Year and Date
  2010-12-04
- Data Source
  KAKENHI-PROJECT-22790921
[Presentation] Differences in high molecular weight adiponectin and adiponectin receptor alterations based on exercise and diet, Integrative Physiology of Exercise2010
- Author(s)
  Tobina T, Nakashima H, Kozako T, et al
- Place of Presentation
  Miami, Florida
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-22790921
[Presentation] NAD依存性脱アセチル化酵素SIRT1及び転写因子FOXO1による筋細胞の分化制御2010
- Author(s)
  野見山融、本田伸一郎、小迫知弘
- Organizer
  第27回日本薬学会九州支部大会
- Place of Presentation
  長崎市
- Year and Date
  2010-12-12
- Data Source
  KAKENHI-PROJECT-22790921
[Presentation] 中枢神経系におけるPAI 1の神経栄養因子としての機能2010
- Author(s)
  添田秦司、小柳悟、蔵元佑嘉子、木村公彦、小田真稔、小迫知弘
- Organizer
  第87回日本生理学会大会
- Place of Presentation
  盛岡市
- Year and Date
  2010-05-19
- Data Source
  KAKENHI-PROJECT-22790921
[Presentation] IRT1を標的としたATLの新規治療法の開発2010
- Author(s)
  小迫知弘、占野廣司、有馬直道
- Organizer
  第69回日本癌学会総会
- Place of Presentation
  大阪市
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-22790921
[Presentation] Immunological Function against Human T-lymphotrophic virus type I in Carriers with Collagen Diseases and HAM/TSP2008
- Author(s)
  Kozako T., et.al.
- Organizer
  The American Society of Hematology 50th Annual Meeting
- Place of Presentation
  San Francisco, CA
- Year and Date
  2008-12-07
- Data Source
  KAKENHI-PROJECT-19790671
[Presentation] HTLV-1特異的CTL疲弊におけるPD-1/PD-L1経路の関与2008
- Author(s)
  小迫知弘ら
- Organizer
  第1回HTLV-1研究会
- Place of Presentation
  東京都
- Year and Date
  2008-08-23
- Data Source
  KAKENHI-PROJECT-19790671
[Presentation] TLV-1/HBcキメラ粒子による効率的HTLV-1特異的CTL誘導法2008
- Author(s)
  小迫知弘、平田真哉ら
- Organizer
  第67回日本癌学会総会
- Place of Presentation
  名古屋市
- Year and Date
  2008-10-28
- Data Source
  KAKENHI-PROJECT-19790671
[Presentation] Immunological Function against Human T-lymphotrophic virus type I in Carriers with Collagen Diseases and HAM/TSP.2008
- Author(s)
  Kozako T., Yoshimitsu M., et al.
- Organizer
  he American Society of Hematology 50th Annual Meeting
- Place of Presentation
  San Francisco, CA
- Year and Date
  2008-12-06
- Data Source
  KAKENHI-PROJECT-19790671
[Presentation] HTLV」1特異的CTL疲弊におけるPD-1/PD-Ll経路の関与2008
- Author(s)
  小迫知弘、吉満誠ら
- Organizer
  第1回HTLV-1研究会
- Place of Presentation
  東京都
- Year and Date
  2008-08-23
- Data Source
  KAKENHI-PROJECT-19790671
[Presentation] 無症候性HTLV-1キャリアとHTLV-1感染膠原病患者におけるHTLV-1特異的細胞傷害性T細胞認識エピトープの比較2008
- Author(s)
  秋元正樹、小迫知弘ら
- Organizer
  第53回日本リウマチ学会総会・学術集会
- Place of Presentation
  札幌市
- Year and Date
  2008-04-05
- Data Source
  KAKENHI-PROJECT-19790671
[Presentation] Efficient Induction of HTLV-1-specific CTL by HTLV-1/HBc Chimeric Particle without Adjuvant as a Prophylactic for HTLV-1-associated T-cell Leukemia.2008
- Author(s)
  Kozako T., Fukada K., et al.
- Organizer
  The American Society of Hematology 50th Annual Meeting
- Place of Presentation
  San Francisco、CA
- Year and Date
  2008-12-06
- Data Source
  KAKENHI-PROJECT-19790671
[Presentation] Efficient Induction of HTLV-1-specific CTL by HTLV-1/HBc Chimeric Particle without Adjuvant as a Prophylactic for HTLV-1-associated T-cell Leukemia2008
- Author(s)
  Kozako T., et.al.
- Organizer
  The American Society of Hematology 50th Annual Meeting
- Place of Presentation
  San Francisco, CA
- Year and Date
  2008-12-07
- Data Source
  KAKENHI-PROJECT-19790671
[Presentation] HTLV-1/HBcキメラ粒子による効率的HTLV-1特異的CTL誘導法2008
- Author(s)
  小迫知弘ら
- Organizer
  第67回日本癌学会総会
- Place of Presentation
  名古屋市
- Year and Date
  2008-10-28
- Data Source
  KAKENHI-PROJECT-19790671
[Presentation] Serum Anti-Tax Antibody Correalates to Lowere Neutrophil Counts in Patientes with HTLV-1 Infection.2007
- Author(s)
  Hamada, H., Matsushita, K., Akimoto, M., Arima, N., Sawada, T., Kozako, T., et. al.
- Organizer
  13th International Conference of Human Retrovivology; HTLV
- Place of Presentation
  Hakone, Japan
- Year and Date
  2007-05-22
- Data Source
  KAKENHI-PROJECT-19790671
[Presentation] 成人T細胞白血病リンパ腫におけるPD-1/PD-L1経路の関与の検討2007
- Author(s)
  吉満誠、小迫知弘ら
- Organizer
  第69回日本血液学会総会・第49回日本臨床血液学会総会
- Place of Presentation
  横浜市
- Year and Date
  2007-10-10
- Data Source
  KAKENHI-PROJECT-19790671
[Presentation] Deficiency of CTL function in adult T-cell leukemia patientsmediated by interaction of PD-l and PD-Ll2007
- Author(s)
  Kozako,T.,Ybshimitsu,M.,etal
- Organizer
  13th International Confbrence of Human Retrovivology
- Place of Presentation
  Hakone, Japan
- Year and Date
  2007-05-22
- Data Source
  KAKENHI-PROJECT-19790671
[Presentation] Deficiency of CTL function in adult T-cell leukemia patients mediated by interaction of PD-1 and PD-L12007
- Author(s)
  Kozako. T. Yoshimitsu, M., et. al.
- Organizer
  13th International Conference of Human Retrovivology; HTLV
- Place of Presentation
  Hakone, Japan
- Year and Date
  2007-05-22
- Data Source
  KAKENHI-PROJECT-19790671
[Presentation] Exhaustion of HTLV-lTax specific CTL in HTLV-1 carriers and adultTcellleukemiapatientsbyPD-1/PD-Llpathway2007
- Author(s)
  小迫知弘、有馬直道
- Organizer
  第66回日本癌学会総会
- Place of Presentation
  横浜市
- Year and Date
  2007-10-03
- Data Source
  KAKENHI-PROJECT-19790671
[Presentation] ATLLにみられるHTLV-1特異的CTLの機能不全におけるPD-1/PD-L1経路の関与2007
- Author(s)
  小迫知弘、吉満誠, ら
- Organizer
  第1回次世代を担う若手医療薬科学シンポジウム
- Place of Presentation
  東京都
- Year and Date
  2007-12-15
- Data Source
  KAKENHI-PROJECT-19790671
[Presentation] Exhaustion of HTLV-1 Tax specific CTL in HTLV-1 carriers and adult T cell leukemia patients by PD-1/PD-L1 pathway2007
- Author(s)
  小迫知弘、有馬直道
- Organizer
  第66回日本癌学会総会
- Place of Presentation
  横浜市
- Year and Date
  2007-10-04
- Data Source
  KAKENHI-PROJECT-19790671
[Presentation] CTL exhaustion in persistent HTLV-1 infection and ATLL is restored through PD-1/PD-L1 pathway2007
- Author(s)
  Kozako. T., Yoshimitsu, M., et. al.
- Organizer
  The American Society of Hematology 49th Annual Meeting
- Place of Presentation
  Atlanta, Georgia
- Year and Date
  2007-12-08
- Data Source
  KAKENHI-PROJECT-19790671
[Presentation] ATLLにみられるHTLV-1特異的CTLの機能不全におけるPD-1/PD-Ll経路の関与2007
- Author(s)
  小迫知弘、吉満誠ら
- Organizer
  第1回次世代を担う若手医療薬科学シンポジウム
- Place of Presentation
  東京都
- Year and Date
  2007-12-15
- Data Source
  KAKENHI-PROJECT-19790671
[Presentation] CTL exhaustion in persistent HTLV-1 infection and ATLL is restored through PD-1/PD-L1 pathway.2007
- Author(s)
  Kozako, T., Yoshimitsu, M., et al.
- Organizer
  The American Society of Hematology 49th Annual Meeting
- Place of Presentation
  Atlanta, Georgia
- Year and Date
  2007-12-08
- Data Source
  KAKENHI-PROJECT-19790671
[Presentation] 膠原病合併HTLV-1キャリアにおいて特異的CTLが認識するHTLV-1エピトープの解析2007
- Author(s)
  北國うらら、小迫知弘ら
- Organizer
  第24回日本薬学会九州支部大会
- Place of Presentation
  福岡市
- Year and Date
  2007-12-07
- Data Source
  KAKENHI-PROJECT-19790671
[Presentation] SerumAnti-Tax Antibody Correalates to Lowere Neutrophil Counts in Patientes with HTLV-lInfection.2007
- Author(s)
  Hamada, H., Matsushita, K., Akimoto, M., Arima, N., Sawada, T., Kozako, T.,etal.
- Organizer
  13th International Confbrence of Human Retrovivology
- Place of Presentation
  HTLV Hakone,Japan
- Year and Date
  2007-05-22
- Data Source
  KAKENHI-PROJECT-19790671

1. SUZUKI Takayoshi (90372838)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
2. YOSHIMITSU Makoto (70404530)

# of Collaborated Projects: 2 results

# of Collaborated Products: 17 results
3. Arima Naomichi (30175997)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. 久保田龍二 (70336337)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 大杉剛生

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
6. 相澤修

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 田中宏暁

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kozako Tomohiro 小迫 知弘

KOZAKO Tomohiro 小迫 知弘

Research Projects

Research Products

Co-Researchers

タンパク質分解誘導キメラ分子創薬による新規白血病治療法の開発Principal Investigator

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Novel epigenetic control compounds induce cell death in leukemia cellsPrincipal Investigator

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Novel small-molecule sirtuin inhibitors induce cell death in leukemia cellsPrincipal Investigator

Principal Investigator

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Novel small-molecule sirtuin inhibitors induce cell apoptic death in leukemia cellsPrincipal Investigator

Principal Investigator

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Development of HTLV-1 peptide vaccine for treatment and prevention of ATL

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Novel small-molecule SIRT1 inhibitors induce cell death in leukaemia cellsPrincipal Investigator

Principal Investigator

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SIRT1, a longevity gene encoded protein, regulates apoptosis of adult T-cell leukemia cells and its inhibition by sirtinol induces apoptosisPrincipal Investigator

Principal Investigator

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Efficient Induction of HTLV-1-specific CTL by HTLV-1/HBc Chimeric Particle without Adjuvant as a Prophylactic for HTLV-1-associated T-cell LeukemiaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] Epigenetic Control Using Small Molecules in Cancer2020

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[Book] 薬学生のための病態検査学 改訂第3版2018

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[Book] 薬学生のための病態検査学 改訂第2版2014

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[Book] T-Cell Leukemia - Characteristics, Treatment and Prevention2013

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[Book] Major Histocompatibility Complex: Biology, Functions and Roles in Disease2012

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Kozako Tomohiro 小迫知弘

KOZAKO Tomohiro 小迫知弘

[Book] 薬学生のための病態検査学改訂第3版2018

[Book] 薬学生のための病態検査学改訂第2版2014