Akahane Tomoko 赤羽智子

… Alternative Names

赤羽智子アカハネトモコ

AKAHANE Tomoko 赤羽智子

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Researcher Number	40398699
Other IDs
Affiliation (Current)	2025: 新渡戸文化短期大学, その他部局等, 准教授
Affiliation (based on the past Project Information) *help	2023: 慶應義塾大学, 医学部(信濃町), 特任助教 2023: 新渡戸文化短期大学, その他部局等, 准教授 2019 – 2021: 慶應義塾大学, 医学部(信濃町), 特任助教 2018: 慶應義塾大学, 医学部(信濃町), 助教 2016 – 2017: 慶應義塾大学, 医学部(信濃町), 特任助教 … More 2015: 慶應義塾大学, 医学部, 特任助教 2014: 慶應義塾大学, 医学部, 助教 2012 – 2013: 慶應義塾大学, 医学部, 特任助教 2012: 慶應義塾大学, 医学部, その他 2008 – 2011: Keio University, 医学部, 研究員 2005 – 2007: 昭和大学, 医学部, 特別研究生 Less
Review Section/Research Field	Principal Investigator Obstetrics and gynecology / Basic Section 56040:Obstetrics and gynecology-related Except Principal Investigator Obstetrics and gynecology / Basic Section 56040:Obstetrics and gynecology-related / Tumor biology and related fields
Keywords	Principal Investigator 卵巣癌 / 発癌メカニズム / p53遺伝子 / 卵管 / 卵巣明細胞腺癌 / 卵巣明細胞癌 / 子宮内膜症 / 卵巣類内膜腺癌 / マイクロダイセクション / 卵巣膿腫(Ovarian Cyst) … More / 卵巣類内膜腺癌(OEMC) / 卵巣明細胞癌(OCCA) / 次世代シーケンサー / NGS / RRSO / TP53遺伝子 / 卵管上皮 / 腹腔内癌細胞 / 蛋白発現 / 悪性転化機構 / Hepatocte Nuclear Factor 1β / 異所性子宮内膜症 / 特異マーカー / 発癌機構 / HNF1-β / 間質細胞 / 卵巣上皮細胞 / 17番染色体 / p53蛋白 / 癌化メカニズム / SNIP解析 / 発がんメカニズム / Leaser Microdissection / 1塩基多型 / TP53 / 発癌リスク因子 / 遺伝子多型 / 卵巣子宮内膜症 / 悪性メカニズム / 卵巣卵巣明細胞腺癌 / c-erbB-2 / EGFR / 異型子宮内膜症(Aty) / 子宮内膜症(END) / Progesterone Receptor(PR) / Estrogen Receptor(ER) / 子宮内膜症(Endmetoriosis) … More Except Principal Investigator 卵巣癌 / オルガノイド / 個別化治療 / BRCA1, BRCA2 / リスク低減卵管卵巣摘出術 / ゲノム解析 / コホート研究 / 生殖細胞系列バリアント / BRCA1/2 / BRCA1 BRCA2 / がん予防 / リスク低減 / 遺伝性腫瘍 / 遺伝性乳癌卵巣癌症候群 / BRCA1,BRCA2 / precision medicine / ドラッグリポジショニング / 薬剤感受性試験 / 初代培養 / 薬剤感受性 / 分子標的治療 / copy number polymorphism / 効果予測 / TC療法 / FGF4 / FGF3 / コピー数増幅 / SNP / バイオマーカー / 化学療法 / 分子標的治療薬 Less

Carcinogenic mechanism analysis and establishment new method at early detection of ovarian cancerPrincipal Investigator
- Principal Investigator
  
  赤羽智子
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Nitobe Bunka College
卵巣癌オルガノイドとドライバージーン解析に基づいた難治性卵巣癌個別化治療法の確立
- Principal Investigator
  
  片岡史夫
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  International University of Health and Welfare
Carcinogenic mechanism of ovarian cancer and of examination of ovarian cancer by NGS analysisPrincipal Investigator
- Principal Investigator
  
  AKAHANE Tomoko
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Keio University
Identification of factors related to penetrance and predictive model for ovarian cancer among BRCA1or BRCA2 mutation carriers
- Principal Investigator
  
  Hirasawa Akira
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Research Field
  
  Tumor biology and related fields
- Research Institution
  Okayama University
  Keio University
Mechanism of ovarian cancer carcinogenesis from fallopian tube epithelial cellsPrincipal Investigator
- Principal Investigator
  
  Akahane Tomoko
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Keio University
Towards precision medicine for ovarian cancer using drug sensitivity and resistance testing and genomic analysis
- Principal Investigator
  
  Eichirou Tominaga
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Keio University
The origin of ovarian clear cell carcinoma and endometrioid carcinoma malignant transformation from endometriosisPrincipal Investigator
- Principal Investigator
  
  Akahane Tomoko
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Keio University
Identification of novel bio-marker associated with drug response in ovarian cancer
- Principal Investigator
  
  YAMAGAMI Wataru
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Keio University
The mechanism of carcinogenesis in ovarian clear cellcarcinoma and ovarian endometrioid carcinoma from endometriosis.Principal Investigator
- Principal Investigator
  
  AKAHANE Tomoko
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Keio University
The mechanism of carcinogenesis in ovarian clear cell carcinoma and ovarian endometrioid carcinoma from endometriosis.Principal Investigator
- Principal Investigator
  
  AKAHANE Tomoko
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Keio University
  Showa University
子宮内膜症の卵巣明細胞癌、類内膜腺癌への悪性化メカニズムの解明Principal Investigator
- Principal Investigator
  
  赤羽智子
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Showa University

[Journal Article] 遺伝性腫瘍2023
- Author(s)
  赤羽智子
- Journal Title
  
  新渡戸文化短期大学学術雑誌
  
  Volume: 第14号 Pages: 13-23
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K08809
[Journal Article] Patient-derived ovarian cancer organoids capture the genomic profiles of primary tumours applicable for drug sensitivity and resistance testing2020
- Author(s)
  Nanki Yoshiko, Chiyoda Tatsuyuki, Hirasawa Akira, Ookubo Aki, Itoh Manabu, Ueno Masaru, Akahane Tomoko, Kameyama Kaori, Yamagami Wataru, Kataoka Fumio, Aoki Daisuke.
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 1197-1197
- DOI
  10.1038/s41598-020-69488-9
- NAID
  120006880199
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09833, KAKENHI-PROJECT-20K09630, KAKENHI-PROJECT-19K18651, KAKENHI-PROJECT-17K19611
[Journal Article] Germline multigene panel testing revealed a BRCA2 pathogenic variant in a patient with suspected Lynch syndrome2020
- Author(s)
  Yoshihama Tomoko, Hirasawa Akira, Sugano Kokichi, Yoshida Teruhiko, Ushiama Mineko, Ueki Arisa, Akahane Tomoko, Nanki Yoshiko, Sakai Kensuke, Makabe Takeshi, Yamagami Wataru, Susumu Nobuyuki, Kameyama Kaori, Kosaki Kenjiro, Aoki Daisuke.
- Journal Title
  
  International Cancer Conference Journal
  
  Volume: 10 Issue: 1 Pages: 6-10
- DOI
  10.1007/s13691-020-00449-9
- NAID
  120007004851
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09833, KAKENHI-PROJECT-17K16881, KAKENHI-PROJECT-17K19611
[Journal Article] Establishment and characterization of a new malignant peritoneal mesothelioma cell line, KOG-1, from the ascitic fluid of a patient with pemetrexed chemotherapy resistance.2020
- Author(s)
  Akahane T, Hirasawa A, Imoto I, Okubo A, Itoh M, Nanki Y, Yoshihama T, Tominaga E, Aoki D.
- Journal Title
  
  Hum Cell
  
  Volume: 33 Pages: 272-282
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K19611
[Journal Article] Establishment and Characterization of a New Malignant Peritoneal Mesothelioma Cell Line, KOG-1, From the Ascitic Fluid of a Patient With Pemetrexed Chemotherapy Resistance2020
- Author(s)
  Akahane Tomoko, Hirasawa Akira, Imoto Issei, Okubo Aki, Itoh Manabu, Nanki Yoshiko, Yoshihama Tomoko, Tominaga Eichiro, Aoki Daisuke.
- Journal Title
  
  Hum Cell
  
  Volume: 33 Issue: 1 Pages: 272-282
- DOI
  10.1007/s13577-019-00286-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09298, KAKENHI-PROJECT-18H02894, KAKENHI-PROJECT-17K19611, KAKENHI-PROJECT-19K09833
[Journal Article] GSTP1 rs1695 is associated with both hematological toxicity and prognosis of ovarian cancer treated with paclitaxel plus carboplatin combination chemotherapy: a comprehensive analysis using targeted resequencing of 100 pharmacogenes2018
- Author(s)
  Yoshihama T, Fukunaga K, Hirasawa A, Nomura H, Akahane T, Kataoka F, Yamagami W, Aoki D, Mushiroda T
- Journal Title
  
  Oncotarget
  
  Volume: 9 Issue: 51 Pages: 29789-29800
- DOI
  10.18632/oncotarget.25712
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09297, KAKENHI-PROJECT-17K19611, KAKENHI-PROJECT-17K15387, KAKENHI-PROJECT-16K11155
[Journal Article] Prevalence of pathogenic germline variants detected by multigene sequencing in unselected Japanese patients with ovarian cancer2017
- Author(s)
  Hirasawa Akira、Imoto Issei、Naruto Takuya、Akahane Tomoko、Yamagami Wataru、Nomura Hiroyuki、Masuda Kiyoshi、Susumu Nobuyuki、Tsuda Hitoshi、Aoki Daisuke
- Journal Title
  
  Oncotarget
  
  Volume: 8 Issue: 68 Pages: 112258-112267
- DOI
  10.18632/oncotarget.22733
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K11155, KAKENHI-PROJECT-16K11156, KAKENHI-PROJECT-17K19611, KAKENHI-PROJECT-15K08949, KAKENHI-PROJECT-16K15618
[Journal Article] UGT1A1 polymorphism as a prognostic indicator of stage I ovarian clear cell carcinoma patients treated with irinotecan.2017
- Author(s)
  Yoshihama T, Hirasawa A, Nomura N, Akahane T, Nanki Y, Yamagami W, Kataoka F, Tominaga T, Susumu N, Mushiroda T, Aoki D.
- Journal Title
  
  Jpn J Clin Oncol
  
  Volume: 47(2) Issue: 2 Pages: 170-174
- DOI
  10.1093/jjco/hyw163
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K10730, KAKENHI-PROJECT-16K11155, KAKENHI-PROJECT-16K11156
[Journal Article] Clinical utility of a self-administered questionnaire for assessment of hereditary gynecologic cancer.2017
- Author(s)
  Masuda K, Hirasawa A, Irie-Kunitomi H, Akahane T, Ueki A, Kobayashi Y, Yamagami W, Nomura H, Kataoka F, Tominaga E, Banno K, Susumu N, Aoki D.
- Journal Title
  
  Jpn J Clin Oncol.
  
  Volume: Mar 13:1. Issue: 5 Pages: 401-406
- DOI
  10.1093/jjco/hyx037
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K11155, KAKENHI-PROJECT-16K11156, KAKENHI-PROJECT-17K19611
[Journal Article] Osteoporosis is less frequent in endometrial cancer survivors with hypertriglyceridemia.2015
- Author(s)
  Hirasawa A, Makita K, Akahane T, Yamagami W, Makabe T, Yokota M, Horiba Y, Ogawa M, Yanamoto S, Deshimaru R, Tominaga E, Banno K, Susumu N, Aoki D
- Journal Title
  
  Jpn J Clin Oncol
  
  Volume: 45(1) Issue: 1 Pages: 127-31
- DOI
  10.1093/jjco/hyu164
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24592530, KAKENHI-PROJECT-25462609, KAKENHI-PROJECT-25462611, KAKENHI-PROJECT-25462612
[Journal Article] Polymorphisms of estrogen metabolism-related genes ESR1, UGT2B17, and UGT1A1 are not associated with osteoporosis in artificial menopausal Japanese women.2015
- Author(s)
  Yokota M, Hirasawa A, Makita K, Akahane T, Sakai K, Makabe T, Horiba Y, Yamagami W, Ogawa M, Iwata T, Yanamoto S, Deshimaru R, Banno K, Susumu N, Aoki D.
- Journal Title
  
  Menopause Review
  
  Volume: 14(3) Pages: 161-167
- DOI
  10.5114/pm.2015.54339
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25462609, KAKENHI-PROJECT-25462611, KAKENHI-PROJECT-25462612
[Journal Article] Family history and BRCA1/BRCA2 status among Japanese ovarian cancer2014
- Author(s)
  Hirasawa A, Masuda K, Akahane T, Kataoka F, Tominaga E, Makita K, Aoki D.
- Journal Title
  
  Jpn J Clin Oncol 44(1) 49-46 2014
  
  Volume: 44(1) Pages: 46-49
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25462611
[Journal Article] Hypertriglyceridemia is frequent in endometrial cancer survivors.2013
- Author(s)
  Hirasawa A, Makita K, Akahane T, Yokota M, Yamagami W, Banno K, Susumu N, Aoki D.
- Journal Title
  
  Jpn J Clin Oncol
  
  Volume: 43(11) Issue: 11 Pages: 1087-1092
- DOI
  10.1093/jjco/hyt125
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25462609, KAKENHI-PROJECT-25462611
[Journal Article] The origin of stroma surrounding epithelial ovarian cancer cells.2013
- Author(s)
  Akahane T, Hirasawa A, Tsuda H, Kataoka F, Nishimura S, Tanaka H, Tominaga E, Nomura H, Chiyoda T, Iguchi Y, Yamagami W, Susumu N, Aoki D.
- Journal Title
  
  Int J Gynecol Pathol
  
  Volume: 32 Pages: 26-30
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25462611
[Journal Article] The origin of stroma surrounding epithelial ovarian cancer cells.2013
- Author(s)
  AkahaneT, Hirasawa A, Tsuda H, Kataoka F, Ni shi mura S, TanakaH, Tominag E, Nomura H, ChiyodaT, IguchiY, Yamagami W, SusumuN, AokiD
- Journal Title
  
  International Journal of Gynecological Pathology
  
  Volume: 32(1) Pages: 26-30
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791545
[Journal Article] Establishment of a system for performing risk-reducing salpingo-oophorectomy for BRCA1 or BRCA2mutation carriers in Japan: Our challenges for the future.2013
- Author(s)
  Hirasawa A, Masuda K, Akahane T, Tsuruta T, Banno K, Makita K, Susumu N, Sugano K, Kosaki K, Aoki D
- Journal Title
  
  Jpn J Clin Oncol
  
  Volume: 43(5) Pages: 515-519
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791545
[Journal Article] Establishment of a system for performing risk-reducing salpingo-oophorectomy2013
- Author(s)
  Hirasawa A, Masuda K, Akahane T, Tsuruta T, Banno K, Makita K, Susumu N, Jinno H, Kitagawa Y, Sugano K, Kosaki K, Aoki D.
- Journal Title
  
  Jpn J Clin Oncol
  
  Volume: 43 Pages: 515-519
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25462611
[Journal Article] Distinguishing between lymphangioleiomyomatosis and carcinomatous2013
- Author(s)
  Hirasawa A, Sato T, Ueno M, Akahane T, Susumu N, Betsuyaku T, Aoki D.
- Journal Title
  
  J Clin Oncol
  
  Volume: 31 Pages: 427-29
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25462611
[Journal Article] Polymorphisms of UGT1A1 gene predict adverse effects of irinotecan treatment2013
- Author(s)
  Hirasawa A, Zama T, Masuda K, Akahane T, Nomura H, Kataoka F, Saito K, Okubo K, Tominaga E, Makita K, Susumu N, Kosaki K, Tanigawara Y, Aoki D.
- Journal Title
  
  J Hum Genet
  
  Volume: 58 Pages: 794-798
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25462611
[Journal Article] Lobular endocervical glandular hyperplasia and peritoneal pigmentation associated withPeutz-Jeghers syndrome due to a germline mutation of STK112012
- Author(s)
  Hirasawa A, Akahane T, Kobayashi Y, Masuda K, Banno K, Fujii T, Susumu N, Itsubo T, Kameyama K, Sugano K, Aoki D
- Journal Title
  
  Annals of Oncology
  
  Volume: 23(11) Pages: 2990-2992
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791545
[Journal Article] Lobular endocervical glandular hyperplasia and peritoneal pigmentation associated with Peutz-Jeghers syndrome due to a germline mutation of STK112012
- Author(s)
  Hirasawa A, Akahane T, Kobayashi Y, Masuda K, Banno K, Fujii T, Susumu N, Itsubo T, Kameyama K, Sugano K, Aoki D
- Journal Title
  
  Annlas of Oncology
  
  Volume: 23(11) Pages: 2990-2992
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791545
[Journal Article] Blood-Direct Invaderplus as a new method for genetic testing.2012
- Author(s)
  Hirasawa A, Akahane T, Tanigawara Y, Aoki D
- Journal Title
  
  Technology report Parsonalized Medicine
  
  Volume: 9(6) Pages: 657-663
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791545
[Journal Article] Blood-direct InvaderPlus as a new method for genetic testing2012
- Author(s)
  Hirasawa A, Akahane T, Tanigawara Y, Aoki D.
- Journal Title
  
  Journal of Personalized Medicine
  
  Volume: 9(6) Pages: 657-663
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791545
[Journal Article] EGRI and FOSB gene expressions in cancer stroma are independent prognostic indicators for epithelial ovarian cancer receiving standard therapy2012
- Author(s)
  Kataoka F, Tsuda H, Arao T, Nishimura S, Tanaka H, Nomura H, Chiyoda T, Hirasawa A, Akahane T, Nishio H, Nishio K, Aoki D
- Journal Title
  
  Genes Chromosomes Cancer
  
  Volume: 51(3) Pages: 300-12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791545
[Journal Article] 家系内の遺伝子検査が契機となり早期介入を行ったLynch症候群の一例2011
- Author(s)
  中村加奈子, 平沢晃, 赤羽智子, 他7名
- Journal Title
  
  東京産科婦人科学会会誌
  
  Volume: 第60巻2号 Pages: 293-297
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791545
[Journal Article] A genome-wide association study identifies genetic variants in theCDKN2BASlocus associated with endometriosis in Japanese.2010
- Author(s)
  Uno S, Zembutsu H, Hirasawa A, Takahashi A, Kubo M, Akahane T, Aoki D, Kamatani N, Hirata K, Nakamura Y
- Journal Title
  
  Nat Genet
  
  Volume: 42(8) Pages: 707-710
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791545
[Journal Article] Protein kinase C δ and η differently regulate the expression of loricrin and jun family proteins in human keratinocytes.2010
- Author(s)
  N Kamioka, T Akahane, M Ohba, et al.
- Journal Title
  
  Biopilys Res Commun
  
  Volume: Mar 26;394(1) Pages: 106-110
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791545
[Journal Article] Association between copy number variations of estorogen matabolism-related gene and bone mineral density in postmenopausal women of Japanese.2010
- Author(s)
  A Hirasawa, T Akahane, D Aoki, et al.
- Journal Title
  
  Osteoporosis Int
  
  Volume: 21(5)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791545
[Journal Article] Protein kinase C δand ηdifferently regulate the expression of loricrin and jun family proteins in human keratinocytes.2010
- Author(s)
  Kamioka N, Akahane T, Kohno Y, Kuroki T, Iijima M, Honma I, Ohba M
- Journal Title
  
  Biophys Res Commun
  
  Volume: 394(1) Pages: 106-110
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791545
[Journal Article] Association between copy number variations of estorogen matabolism-related gene and bone mineral density in postmenopausal women of Japanese2010
- Author(s)
  Hirasawa A, Akahane T, Makita K, Aoki D
- Journal Title
  
  Osteoporosis Int
  
  Volume: 21(5)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791545
[Journal Article] 両側卵巣摘出術施行例における骨代謝関連遺伝子の探索2010
- Author(s)
  平沢晃、赤羽智子、牧田和也、青木大輔
- Journal Title
  
  Osteoporosis japan
  
  Volume: 18(3) Pages: 58-60
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791545
[Journal Article] ヒト三次元培養皮膚への遺伝子導入法の確立と表皮分化へのCキナーゼの関与2010
- Author(s)
  上岡なぎさ、赤羽智子、大場基, 他3名
- Journal Title
  
  昭和医学会誌 (in press)
- NAID
  130000852909
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19791168
[Journal Article] A genome-wide association study identifies genetic variants in the CDKN2BAS locus associated with endometriosis in Japanese.2010
- Author(s)
  S Uno, T Akahane, Y Nakamura, et al.
- Journal Title
  
  Nater Genetics.
  
  Volume: 42(8) Pages: 707-710
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791545
[Journal Article] ヒト三次元培養皮膚への遺伝子導入法の確立と表皮分化へのCキナーゼの関与2010
- Author(s)
  上岡なぎさ, 本間生夫, 赤羽智子, 大場基, 他2名
- Journal Title
  
  昭和医学会誌
  
  Volume: 70(3) Pages: 253-262
- NAID
  130000852909
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791545
[Journal Article] Protein kinase C δ and η differently regulate the expression of loricrin and Jun family proteins in human keratinocytes.2010
- Author(s)
  Nagisa Kamioka, Tomoko Akahane, Motoi Ohba, et al
- Journal Title
  
  Biochemical and Biophysical Research Communications (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19791168
[Journal Article] The role of P53 mutation in the carcinogenesis from endometriosis.2007
- Author(s)
  Akahane T, Sekizawa A, Purwosunu Y, Nagatsuka M, Okai T.
- Journal Title
  
  Int J Gynecol Pathol 26
  
  Pages: 345-351
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19791168
[Journal Article] The Role of p53 mutation in the carcinomas Arising from Endometriosis2007
- Author(s)
  Tomoko, Akahane・Akihiko, Sekizawa, et. al.
- Journal Title
  
  International Journal of Gynecological Pathology Vol. 26・3
  
  Pages: 345-351
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19791168
[Journal Article] Disappearance of Steroid Hormone Dependency During Malignant Transformation of Ovarian Clear Cell Cancer2005
- Author(s)
  Tomoko Akahane, Akihiko Sekizawa et al.
- Journal Title
  
  International Journal of Gynecological Pathology 24
  
  Pages: 369-376
- Data Source
  KAKENHI-PROJECT-17791138
[Journal Article] The role of p53 mutation in the carcinogenesis from endmetoriosis.
- Author(s)
  Tomoko Akahane, Akihiko Sekizawa et al.
- Journal Title
  
  International Journal of Gynecological Pathology (掲載待ち)
- Data Source
  KAKENHI-PROJECT-17791138
[Patent] バイオマーカーとしてのマイクロRNAを用いた婦人科がんの診断・治療選択2008
- Inventor(s)
  座間猛, 平沢晃, 齋藤康一郎, 赤羽智子
- Industrial Property Rights Holder
  座間猛, 平沢晃, 齋藤康一郎, 赤羽智子
- Filing Date
  2008-12-24
- Data Source
  KAKENHI-PROJECT-19791168
[Patent] バイオマーカーとしてのマイクロRNAを用いた婦人科がんの診断・治療選択2008
- Inventor(s)
  座間猛平沢晃齋藤康一郎赤羽智子
- Industrial Property Rights Holder
  座間猛平沢晃齋藤康一郎赤羽智子
- Filing Date
  2008-12-04
- Data Source
  KAKENHI-PROJECT-19791168
[Patent] バイオマーカーとしてのマイクロRNAを用いた婦人科がんの診断・治療選択2008
- Inventor(s)
  座間猛, 平沢晃, 齋藤康一郎, 赤羽智子
- Industrial Property Rights Holder
  座間猛, 平沢晃, 齋藤康一郎, 赤羽智子
- Filing Date
  2008-12-04
- Data Source
  KAKENHI-PROJECT-19791168
[Patent] バイオマーカーとしてのマイクロRNAを用いた婦人科がんの診断・治療選択2008
- Inventor(s)
  座間猛平沢晃齋藤康一郎赤羽智子
- Industrial Property Rights Holder
  座間猛平沢晃齋藤康一郎赤羽智子
- Acquisition Date
  2008-12-24
- Data Source
  KAKENHI-PROJECT-19791168
[Presentation] 初代卵巣癌組織を用いた3次元オルガノイド培養法の確立2021
- Author(s)
  南木佳子, 千代田達幸, 平沢晃, 大久保亜紀, 伊藤学, 赤羽智子, 早乙女啓子, 同前愛, 平野卓朗, 黒田由香, 吉村拓馬, 山上亘, 片岡史夫, 青木大輔
- Organizer
  第62回日本婦人科腫瘍学会
- Data Source
  KAKENHI-PROJECT-20K09630
[Presentation] RRSO検体におけるp53 signatureとSTICの特性に関する検討2021
- Author(s)
  赤羽智子, 増田健太, 平沢晃, 小林佑介, 永井晋平, 千代田達幸, 林茂徳, 片岡史夫, 冨永英一郎, 阪埜浩司, 田中守, 青木大輔
- Organizer
  第73回日本産科婦人科学会学術講演会
- Data Source
  KAKENHI-PROJECT-20K09630
[Presentation] 初代卵巣癌組織を用いた 3 次元オルガノイド培養法の確立.2021
- Author(s)
  南木佳子, 千代田達幸, 平沢晃, 大久保亜紀, 伊藤学, 赤羽智子, 早乙女啓子, 同前愛, 平野卓朗, 黒田由香, 吉村拓馬, 山上亘, 片岡史夫, 青木大輔.
- Organizer
  第62回日本婦人科腫瘍学会学術講演会
- Data Source
  KAKENHI-PROJECT-17K19611
[Presentation] p53の機能障害はマウス卵管オルガノイドの分化を阻害する2021
- Author(s)
  永井晋平 , 増田健太, 田村友宏, 大槻雄士, 推名健太郎, 信末博行, 赤羽智子, 千代田達幸, 小林佑介, 阪埜浩司, 青木大輔, 佐谷秀行, 永野修.
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K09833
[Presentation] 初代卵巣癌組織を用いた3次元オルガノイド培養法の確立2021
- Author(s)
  南木佳子, 千代田達幸, 平沢晃, 大久保亜紀, 伊藤学, 赤羽智子, 早乙女啓子, 同前愛, 平野卓朗, 黒田由香, 吉村拓馬, 山上亘, 片岡史夫, 青木大輔.
- Organizer
  第64回日本婦人科腫瘍学会学術講演会
- Data Source
  KAKENHI-PROJECT-19K09833
[Presentation] RRSO検体におけるp53 signatureとSTICの特性に関する検討2021
- Author(s)
  赤羽智子, 増田健太, 平沢晃, 小林佑介, 永井晋平, 千代田達幸, 林茂徳, 片岡史夫, 冨永英一郎, 阪埜浩司, 田中守, 青木大輔.
- Organizer
  第73回日本産科婦人科学会学術講演会
- Data Source
  KAKENHI-PROJECT-19K09833
[Presentation] 悪性腹膜中皮腫細胞株KOG-1の3次元立体培養と2次元平面培養によるPEM薬剤感受性の比較2020
- Author(s)
  赤羽智子, 平沢晃, 冨永英一郎, 井本逸勢, 大久保亜希, 伊藤学, 南木佳子, 吉浜智子, 増田健太, 千代田達幸, 山上亘, 片岡史夫, 青木大輔.
- Organizer
  第61回　日本臨床細胞学会総会春期大会
- Data Source
  KAKENHI-PROJECT-20K09630
[Presentation] Primary tissue ovarian cancer organoids capturing histological and genetical features of the original tumor and applications in drug resistance and sensitivity testing.2020
- Author(s)
  Nanki Y, Chiyoda T, Hirasawa A, Akahane T, Yamagami W, Kataoka F, Tanaka M, Aoki D.
- Organizer
  第72回日本産科婦人科学会学術講演会
- Data Source
  KAKENHI-PROJECT-17K19611
[Presentation] 卵巣癌オルガノイドは元腫瘍組織の遺伝学的特徴を有する.2020
- Author(s)
  南木佳子, 千代田達幸, 平沢晃, 大久保亜紀, 伊藤学, 吉村拓馬, 赤羽智子, 山上亘, 青木大輔.
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K19611
[Presentation] BRCA1 VUS保持卵巣癌例おけるバリアントの病的意義に関する検討2020
- Author(s)
  赤羽智子, 西原広史, 平沢　晃, 井本逸勢, 増田健太, 坂本一平, 野原祥夫, 谷嶋成樹, 青木大輔.
- Organizer
  第26回　日本遺伝性腫瘍学会
- Data Source
  KAKENHI-PROJECT-19K09833
[Presentation] Primary tissue ovarian cancer organoids capture histological and genetical features of the original tumor which can be applied to drug sensitivity testing2020
- Author(s)
  Nanki Yoshiko, Chiyoda Tatsuyuki, Hirasawa Akira, Akahane Tomoko, Yamagami Wataru, Kataoka Fumio, Tanaka Mamoru, Aoki Daisuke.
- Organizer
  第72回　日本産科婦人科学会学術講演会
- Data Source
  KAKENHI-PROJECT-19K09833
[Presentation] 悪性腹膜中皮腫細胞株KOG-1の3次元立体培養と2次元平面培養によるPEM薬剤感受性の比較2020
- Author(s)
  赤羽智子, 平沢　晃, 冨永英一郎, 井本逸勢, 大久保亜希, 伊藤学, 南木佳子, 吉浜智子, 増田健太, 千代田達幸, 山上亘, 片岡史夫, 青木大輔.
- Organizer
  第61回　日本臨床細胞学会総会春期大会
- Data Source
  KAKENHI-PROJECT-19K09833
[Presentation] Ovarian cancer organoids recapitulate genomic alterations of the parental tumors2020
- Author(s)
  南木佳子, 千代田達幸, 平沢晃, 大久保亜紀, 伊藤　学, 吉村拓馬, 赤羽智子, 山上亘, 青木大輔.
- Organizer
  第79回　日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K09833
[Presentation] 卵巣癌発症との関連性が推測されたBRCA1遺伝子のVUSに関する検討2019
- Author(s)
  赤羽智子, 西原広史, 平沢　晃, 井本逸勢, 坂本一平, 野原祥夫, 谷嶋成樹, 青木大輔.
- Organizer
  第5回　日本産科婦人科遺伝診療学会学術講演会
- Data Source
  KAKENHI-PROJECT-19K09833
[Presentation] 卵巣癌オルガノイド培養系の確立と卵巣癌組織とのゲノム解析による比較2019
- Author(s)
  南木佳子，千代田達幸，平沢晃，赤羽智子，早乙女啓子，同前愛，平野卓朗，黒田由香，吉村拓馬，山上亘，片岡史夫，青木大輔
- Organizer
  第5回日本産科婦人科遺伝診療学会学術講演会
- Data Source
  KAKENHI-PROJECT-17K19611
[Presentation] Circulating tumor DNA as a novel biomarker for ovarian cancer monitoring.2019
- Author(s)
  Nanki Y, Hirasawa A, Chen Y, George AM, Akahane T, Chiyoda T, Nomura H, Saal LH, Tanaka M, Aoki D.
- Organizer
  第71回日本産科婦人科学会学術講演会
- Data Source
  KAKENHI-PROJECT-17K19611
[Presentation] Utility of plasma circulating tumor DNA in ovarian cancer monitoring.2019
- Author(s)
  Nanki Y, George A, Chen Y, Brueffer C, Chiyoda T, Akahane T, Hirasawa A, Aoki D, Saal L.
- Organizer
  The 6th Biennial Meeting of Asian Society of Gynecologic Oncology (ASGO 2019 )
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19611
[Presentation] 卵巣癌発症との関連性が推測されたBRCA1 遺伝子のVUS に関する検討2019
- Author(s)
  赤羽智子，西原広史，平沢晃，井本逸勢，坂本一平，野原祥男，谷嶋成樹，青木大輔
- Organizer
  第5回日本産科婦人科遺伝診療学会学術講演会
- Data Source
  KAKENHI-PROJECT-17K19611
[Presentation] Germline pathogenic variants of cancer susceptibility genes among Japanese ovarian cancer patients.2019
- Author(s)
  Hirasawa A, Imoto I, Naruto T, Akahane T, Yamagami W, Nomura H, Masuda K, Susumu N, Tsuda H, Aoki D.
- Organizer
  European Human Genetics Conference 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19611
[Presentation] Plasma circulating tumor DNA as a genomic biomarker for ovarian cancer.2019
- Author(s)
  Nanki Y, George A, Chen Y, Brueffer C, Chiyoda T, Akahane T, Hirasawa A, Aoki D, Saal L.
- Organizer
  European Human Genetics Conference 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19611
[Presentation] Circulating tumor DNA as a novel biomarker for recurrence and treatment response in ovarian cancer patients2019
- Author(s)
  Nanki Y, Hirasawa A, Chen Y, George A, AkahaneT, Chiyoda T, Nomura H, Saal L, Tanaka M, Aoki D
- Organizer
  第71回　日本産科婦人科学会学術講演会
- Data Source
  KAKENHI-PROJECT-19K09833
[Presentation] 乳癌既往歴があり耳下腺癌を発症したBRCA1 germline pathogenic variant保持者の１例2018
- Author(s)
  赤羽智子、平沢晃、片岡史夫、野村弘行、山下年成、羽田恵梨、亀山香織、小崎健次郎、青木大輔
- Organizer
  第68回日本人類遺伝学会
- Data Source
  KAKENHI-PROJECT-16K11155
[Presentation] がん遺伝子パネル検査にてPMS2遺伝子に生殖細胞系列バリアントが検出された1例2018
- Author(s)
  赤羽智子、平沢晃、西原広史、植木有紗、谷嶋成樹、千代田達幸、岸郁子、青木大輔
- Organizer
  第4回日本婦人科遺伝子診療学会
- Data Source
  KAKENHI-PROJECT-16K11155
[Presentation] GSTP1 rs1695 is a predictive indicator of both hematological toxicity and prognosis of ovarian cancer treated with paclitaxel plus carboplatin2018
- Author(s)
  Tomoko Yoshihama, Akira Hirasawa, Hiroyuki Nomura, Tomoko Akahane, Fumio Kataoka, Wataru Yamagami, Taisei Mushiroda, Mamoru Tanaka, Daisuke Aoki
- Organizer
  第70回日本産科婦人科学会学術講演会
- Data Source
  KAKENHI-PROJECT-16K11155
[Presentation] 個別化医療を目指した腹水および組織由来卵巣癌細胞の初代3次元(3D)細胞培養法の確立2018
- Author(s)
  南木佳子、平沢晃、野村弘行、赤羽智子、早乙女啓子、同前愛、千代田達幸、片岡史夫、冨永英一郎、青木大輔
- Organizer
  第59回日本臨床細胞学会総会（春期大会）
- Data Source
  KAKENHI-PROJECT-16K11155
[Presentation] Germline variants of cancer susceptibility genes for ovarian, fallopian tube, and peritoneal cancers in Japanese2018
- Author(s)
  Hirasawa A, Imoto I, Naruto T, Akahane T, Yamagami W, Nomura H, Masuda K, Susumu N, Tsuda H, Aoki D.
- Organizer
  The 57th Annual Congress of Taiwan Association of Obstetrics and Gynecology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19611
[Presentation] The contribution of germline pathogenic variants of cancer susceptibility genes for primary ovarian, fallopian tube, and peritoneal cancers in Japanese2017
- Author(s)
  Hirasawa A,Issei I,Naruto T,Akahane T,Yamagami W,Nomura H,Masuda K,Susumu N,Tsuda H,Aoki D
- Organizer
  AACR 2017 Addressing Critical Questions in Ovarian Cancer Research and Treatment
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19611
[Presentation] The contribution of deleterious germ-line mutations of susceptibility genes to ovarian, fallopian tube, and peritoneal cancers in Japanese2017
- Author(s)
  Hirasawa A,Imoto I,Naruto T,Akahane T,Yamagami W,Susumu N,Tsuda H,Aoki D
- Organizer
  AACR Annual Meeting 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19611
[Presentation] 腹水卵巣癌細胞のCD44各アイソフォーム発現量と化学療法の効果との関連性の検討2017
- Author(s)
  蔦幸児,冨永英一郎,戸澤晃子,赤羽智子,大原樹,小林佑介,平沢晃,阪埜浩司, 鈴木直,青木大輔
- Organizer
  第58回日本臨床細胞学会総会（春期大会）
- Data Source
  KAKENHI-PROJECT-16K11155
[Presentation] BRCA1,2変異卵巣癌の血縁者における乳癌および卵巣癌の罹患に関する検討2017
- Author(s)
  岩佐尚美,平沢晃,野村弘行,赤羽智子,千代田達幸,山上亘,片岡史夫,井本逸勢,青木大輔
- Organizer
  第27回日本乳癌検診学会学術総会
- Data Source
  KAKENHI-PROJECT-17K19611
[Presentation] 腹水卵巣癌細胞のCD44各アイソフォーム発現量と化学療法の効果との関連性の検討2017
- Author(s)
  蔦幸児,冨永英一郎,戸澤晃子,赤羽智子,大原樹,小林佑介,平沢晃,阪埜浩司, 鈴木直,青木大輔
- Organizer
  第58回日本臨床細胞学会総会（春期大会）
- Data Source
  KAKENHI-PROJECT-17K19611
[Presentation] UGT1A1 polymorphism may be a prognostic indicator of stage I ovarian clear cell carcinoma patients treated with irinotecan2017
- Author(s)
  Yoshihama T,Hirasawa A,Nomura H,Akahane T,Nanki Y,Yamagami W,Kataoka F,Tominaga E,Susumu N,Mushiroda T,Aoki D
- Organizer
  15th International Congress of Therapeutic Drug Monitoring and Clinical Toxicology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19611
[Presentation] Polymorphisms of the genes ESR1, UGT2B17, and UGT1A1 associated with estrogen metabolism are not associated with osteoporosis in Japanese women after artificial menopause2017
- Author(s)
  Yokota M,Hirasawa A,Kazuya K,Akahane T,Sakai K,Makabe T,Horiba Y,Yamagami W,Ogawa M,Iwata T,Yanamoto S,Deshimaru R,Banno K,Susumu N,Aoki D
- Organizer
  6th Scientific Meeting of the Asia Pacific Menopause Federation
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11155
[Presentation] BRCA1/2変異卵巣癌の血縁者における乳癌および卵巣癌の罹患に関する検討2017
- Author(s)
  岩佐尚美,平沢晃,野村弘行,赤羽智子,千代田達幸,山上亘,片岡史夫,井本逸勢,青木大輔
- Organizer
  第27回日本乳癌検診学会学術総会
- Data Source
  KAKENHI-PROJECT-16K11155
[Presentation] Ascites-derived and tissue-derived ovarian cancer cell primary 3D cultures aimed for personalized medicine2017
- Author(s)
  Nanki Y,Hirasawa A,Nomura H,Okubo A,Itoh M,Akahane A,Chiyoda T,Kataoka F,Tominaga E,Aoki D
- Organizer
  AACR 2017 Addressing Critical Questions in Ovarian Cancer Research and Treatment
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11155
[Presentation] BBRCA1遺伝子病的変異陽性例であり耳下腺癌を発症した１症例2017
- Author(s)
  赤羽智子, 平沢晃, 増田健太, 野村弘行, 片岡史夫, 阪埜浩司, 進伸幸, 亀山香織, 清水哲, 青木大輔
- Organizer
  第58回日本臨床細胞学会総会（春期大会）
- Data Source
  KAKENHI-PROJECT-16K11155
[Presentation] The contribution of deleterious germ-line mutations of susceptibility genes to ovarian, fallopian tube, and peritoneal cancers in Japanese2017
- Author(s)
  Hirasawa A,Imoto I,Naruto T,Akahane T,Yamagami W,Susumu N,Tsuda H,Aoki D
- Organizer
  AACR Annual Meeting 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11155
[Presentation] The contribution of germline pathogenic variants of cancer susceptibility genes for primary ovarian, fallopian tube, and peritoneal cancers in Japanese2017
- Author(s)
  Hirasawa A,Issei I,Naruto T,Akahane T,Yamagami W,Nomura H,Masuda K,Susumu N,Tsuda H,Aoki D
- Organizer
  AACR 2017 Addressing Critical Questions in Ovarian Cancer Research and Treatment
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11155
[Presentation] UGT1A1 polymorphism may be a prognostic indicator of stage I ovarian clear cell carcinoma patients treated with irinotecan2017
- Author(s)
  Yoshihama T,Hirasawa A,Nomura H,Akahane T,Nanki Y,Yamagami W,Kataoka F,Tominaga E,Susumu N,Mushiroda T,Aoki D
- Organizer
  15th International Congress of Therapeutic Drug Monitoring and Clinical Toxicology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11155
[Presentation] Ascites-derived and tissue-derived ovarian cancer cell primary 3D cultures aimed for personalized medicine2017
- Author(s)
  Nanki Y,Hirasawa A,Nomura H,Okubo A,Itoh M,Akahane A,Chiyoda T,Kataoka F,Tominaga E,Aoki D
- Organizer
  AACR 2017 Addressing Critical Questions in Ovarian Cancer Research and Treatment
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19611
[Presentation] Polymorphisms of the genes ESR1, UGT2B17, and UGT1A1 associated with estrogen metabolism are not associated with osteoporosis in Japanese women after artificial menopause2017
- Author(s)
  Yokota M,Hirasawa A,Kazuya K,Akahane T,Sakai K,Makabe T,Horiba Y,Yamagami W,Ogawa M,Iwata T,Yanamoto S,Deshimaru R,Banno K,Susumu N,Aoki D
- Organizer
  6th Scientific Meeting of the Asia Pacific Menopause Federation
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19611
[Presentation] 血縁腫瘍歴聴取票を用いた婦人科関連遺伝性腫瘍のスクリーニングに関する検討.2016
- Author(s)
  平野卓朗，平沢晃，真壁健, 坂井健良, 赤羽智子，増田健太，小林佑介, 山上亘，野村弘行，片岡史夫，冨永英一郎, 阪埜浩司，進伸幸，青木大輔.
- Organizer
  第2回日本産科婦人科遺伝診療学会学術講演会
- Place of Presentation
  京都府京都市メルパルク京都
- Year and Date
  2016-12-16
- Data Source
  KAKENHI-PROJECT-16K11155
[Presentation] 血縁腫瘍歴聴取票を用いた婦人科関連遺伝性腫瘍のスクリーニングに関する検討.2016
- Author(s)
  平野卓朗，平沢晃，真壁健, 坂井健良, 赤羽智子，増田健太，小林佑介, 山上亘，野村弘行，片岡史夫，冨永英一郎, 阪埜浩司，進伸幸，青木大輔.
- Organizer
  第2回日本産科婦人科遺伝診療学会学術講演会
- Place of Presentation
  メルパルク京都(京都府京都市）
- Year and Date
  2016-12-16
- Data Source
  KAKENHI-PROJECT-15K10730
[Presentation] TAS-117, a novel allosteric AKT inhibitor, shows potent antitumor activity on ovarian clear cell adenocarcinoma cells from fresh surgical samples in 3-dimentional culture.2016
- Author(s)
  Tsuta K, Tominaga E, Tozawa A, Akahane T, Uekawa A, Ohara T, Nomura H, Kataoka F, Hirasawa A, Bonno K, Suzuki N, Aoki D.
- Organizer
  第68回日本産科婦人科学会学術講演会
- Place of Presentation
  東京都　東京国際フォーラム
- Year and Date
  2016-04-22
- Data Source
  KAKENHI-PROJECT-16K11155
[Presentation] 自己記入式がん家族歴聴取票を使用した遺伝高リスク家系の抽出.2016
- Author(s)
  國富晴子, 増田健太, 平沢晃, 赤羽智子, 小林佑介, 山上亘, 野村弘行, 片岡史夫, 冨永英一郎, 阪埜浩司, 進伸幸, 青木大輔.
- Organizer
  第22回日本家族性腫瘍学会学術集会
- Place of Presentation
  愛知県松山市ひめぎんホール
- Year and Date
  2016-06-03
- Data Source
  KAKENHI-PROJECT-16K11155
[Presentation] 腹水細胞中から樹立したヒト悪性腹膜中皮腫由来細胞株の特性に関する検討.2016
- Author(s)
  赤羽智子, 冨永英一郎, 平沢晃, 青木大輔.
- Organizer
  第55回日本臨床細胞学会秋期大会
- Place of Presentation
  大分県別府市別府国際コンベンショナルセンター
- Year and Date
  2016-11-18
- Data Source
  KAKENHI-PROJECT-16K11155
[Presentation] TAS-117, a novel allosteric AKT inhibitor, shows potent antitumor activity on ovarian clear cell adenocarcinoma cells from fresh surgical samples in 3-dimentional culture.2016
- Author(s)
  Tsuta K, Tominaga E, Tozawa A, Akahane T, Uekawa A, Ohara T, Nomura H, Kataoka F, Hirasawa A, Bonno K, Suzuki N, Aoki D.
- Organizer
  第68回日本産科婦人科学会学術講演会
- Place of Presentation
  東京国際フォーラム(東京都千代田区）
- Year and Date
  2016-04-21
- Data Source
  KAKENHI-PROJECT-15K10730
[Presentation] 腹水細胞中から樹立したヒト悪性腹膜中皮腫由来細胞株の特性に関する検討.2016
- Author(s)
  赤羽智子, 冨永英一郎, 平沢晃, 青木大輔.
- Organizer
  第55回日本臨床細胞学会秋期大会
- Place of Presentation
  別府国際コンベンションセンター（大分県別府市）
- Year and Date
  2016-11-18
- Data Source
  KAKENHI-PROJECT-15K10730
[Presentation] 自己記入式がん家族歴聴取票を使用した遺伝高リスク家系の抽出.2016
- Author(s)
  國富晴子, 増田健太, 平沢晃, 赤羽智子, 小林佑介, 山上亘, 野村弘行, 片岡史夫, 冨永英一郎, 阪埜浩司, 進伸幸, 青木大輔.
- Organizer
  第22回日本家族性腫瘍学会学術集会
- Place of Presentation
  ひめぎんホール（愛媛県松山市）
- Year and Date
  2016-06-03
- Data Source
  KAKENHI-PROJECT-15K10730
[Presentation] 慶應義塾大学医学部産婦人科におけるバイオバンク2015
- Author(s)
  赤羽智子、平沢晃、増田健太、野田朋美、西尾浩、仲村勝、山上亘、森定徹、野村弘行、片岡史夫、岩田卓、田中京子、冨永英一郎、鈴木淳、阪埜浩司、牧田和也、進伸幸、青木大輔
- Organizer
  第60回　日本人類遺伝学会
- Place of Presentation
  京王プラザホテル（東京都新宿区）
- Year and Date
  2015-10-14
- Data Source
  KAKENHI-PROJECT-25462611
[Presentation] BRCA1/2遺伝子生殖細胞変異例における良性卵管上皮細胞のp53蛋白発現とTP53遺伝子変異の意義2015
- Author(s)
  赤羽智子、平沢　晃、増田健太、片岡史夫、冨永英一郎、阪埜浩司、進　伸幸、田中　守、青木大輔
- Organizer
  第67回　日本産科婦人科学会学術講演会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2015-04-10
- Data Source
  KAKENHI-PROJECT-25462611
[Presentation] 婦人科疾患バイオバンクの現状と家族性腫瘍のスクリーニングに関する検討2015
- Author(s)
  赤羽智子、平沢　晃、増田健太、真壁　健、坂井健良、吉浜智子、山上　亘、野村弘行、片岡史夫、阪埜浩司、進　伸幸、青木大輔
- Organizer
  第1回　日本産科婦人科遺伝子診療学会
- Place of Presentation
  長崎ブリックホール（長崎県長崎市）
- Year and Date
  2015-12-18
- Data Source
  KAKENHI-PROJECT-25462611
[Presentation] 細胞診標本中に出現する微量細胞からの遺伝子解析2015
- Author(s)
  赤羽智子、平沢　晃、冨永英一郎、青木大輔
- Organizer
  第56回　日本臨床細胞学会総会（春期大会）
- Place of Presentation
  松江テルサおよびくにびきメッセ（島根県松江市）
- Year and Date
  2015-06-12
- Data Source
  KAKENHI-PROJECT-25462611
[Presentation] BRCA1/2遺伝子変異保持者における卵管上皮細胞のp53 statusとその意義2013
- Author(s)
  赤羽智子、冨永英一郎、平沢晃、片岡　史夫、増田健太、植木有紗、阪埜　浩司、進伸幸、亀山香織、青木大輔
- Organizer
  第52回日本臨床細胞学会秋期大会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-25462611
[Presentation] 細胞診検体からの遺伝子診断を志向した微量細胞からの遺伝子解析の試み2013
- Author(s)
  赤羽智子、冨永英一郎、山上　亘、野村　弘行、片岡史夫、平沢　晃、進　伸幸、青木大輔
- Organizer
  第54回日本臨床細胞学会総会（春期大会)
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-25462611
[Presentation] TP53 status of fallopian tubes in BRCA1 or BRCA2 mutant patients2013
- Author(s)
  Tomoko Akahane, Akira Hirasawa, Kenta Masuda, Tomohiko Tsuruta, Hiroyuki Nomura, Fumio Kataoka, Eiichiro Tominaga, Kouji Banno, Nobuyuki Susumu, Kaori Kameyama　Daisuke Aoki
- Organizer
  第72回日本癌学会抄録
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-25462611
[Presentation] 日本人卵巣癌における血縁腫瘍歴の頻度およびBRCA1/2遺伝子変異保持者卵管細胞のp53変異に関する検討2013
- Author(s)
  赤羽智子、平沢晃、増田健太、冨永英一郎、片岡史夫、野村弘行、鶴田智彦、植木有紗、阪埜浩司、進伸幸、菅野康吉、小崎健次郎、亀山香織、青木大輔
- Organizer
  第58回日本人類遺伝学会抄録（仙台 2013）
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-25462611
[Presentation] 上皮性卵巣癌におけるGNAS遺伝子の意義とその関連蛋白であるGsαの発現2012
- Author(s)
  冨永英一郎　津田浩史　赤羽智子　他9名
- Organizer
  第64回日本産科婦人科学会学術講演会
- Place of Presentation
  神戸ポートピアホテル　神戸国際展示場
- Data Source
  KAKENHI-PROJECT-22791545
[Presentation] 卵巣明細胞癌細胞株におけるHNF1B蛋白発現解析2012
- Author(s)
  赤羽智子、冨永英一郎、平沢晃、青木大輔
- Organizer
  第53回日本臨床細胞学会春季大会
- Place of Presentation
  千葉県幕張
- Data Source
  KAKENHI-PROJECT-22791545
[Presentation] 臨床的に癌性の体腔液貯留が疑われる症例の細胞診断学的検討2012
- Author(s)
  冨永英一郎　赤羽智子　他5名
- Organizer
  第53回日本臨床細胞学会総会（春期季大会）
- Place of Presentation
  幕張メッセ国際会議場
- Data Source
  KAKENHI-PROJECT-22791545
[Presentation] 卵巣明細胞腺癌細胞におけるHNF1β蛋白発現解析2012
- Author(s)
  赤羽智子　冨永英一郎　平沢　晃　青木大輔
- Organizer
  第53回日本臨床細胞学会総会（春期季大会）
- Place of Presentation
  幕張メッセ国際会議場
- Data Source
  KAKENHI-PROJECT-22791545
[Presentation] 卵巣子宮内膜症からの明細胞腺癌への悪性分化機構の解明2011
- Author(s)
  赤羽智子、関沢明彦, 岡井崇
- Organizer
  第307回昭和医学会
- Place of Presentation
  昭和大学1号館7階講堂(東京都)
- Year and Date
  2011-05-28
- Data Source
  KAKENHI-PROJECT-22791545
[Presentation] STK11遺伝子陽性を示し子宮頸部分葉状頸管過形成を合併したPeuz-Jegher症候群の1例2011
- Author(s)
  赤羽智子、平沢晃, 他7名
- Organizer
  第50回臨床細胞学会秋期大会
- Place of Presentation
  京王プラザホテル(東京都)
- Data Source
  KAKENHI-PROJECT-22791545
[Presentation] STK11遺伝子陽性を示し子宮頸部分葉状頸管過形成を合併したPeuz-Jegher症候群の1例2011
- Author(s)
  赤羽智子、平沢晃、小林佑介、鶴田智彦、阪埜浩司、藤井多久磨、進伸幸、菅野康吉、青木大輔
- Organizer
  第50回臨床細胞学会秋期大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22791545
[Presentation] 抗がん剤のPK/PDとPGx～個別化投薬へ向けてがん臨床現場におけるファーマコゲノミクスの導入2010
- Author(s)
  平沢晃、赤羽智子、青木大輔, 他5名
- Organizer
  第31回日本臨床薬理学会年会(シンポジウム)
- Place of Presentation
  京都
- Year and Date
  2010-12-02
- Data Source
  KAKENHI-PROJECT-22791545
[Presentation] 卵巣癌におけるHNF1B発現特異性と臨床病理学的因子との関連2010
- Author(s)
  赤羽智子、冨永英一郎、平沢晃、進伸幸、青木大輔
- Organizer
  第49回臨床細胞学会秋期大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-22791545
[Presentation] Association between the UGTlA1 polymorphism, bilirubin levels, and dyslipidemia in endometrial cancer.2010
- Author(s)
  Matsumura S, Hirasawa A, Akahane T, et al
- Organizer
  AACR/JCA Joint Conference
- Place of Presentation
  Hawaii, USA
- Data Source
  KAKENHI-PROJECT-19791168
[Presentation] 卵巣癌におけるHNF1B発現特異性と臨床病理学的因子との関連2010
- Author(s)
  赤羽智子、冨永英一郎、平沢晃、進伸幸、青木大輔
- Organizer
  第49回臨床細胞学会秋期大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-22791545
[Presentation] 抗がん剤のPK/PDとPGx～個別化投薬へ向けてがん臨床現場におけるファーマコゲノミクスの導入2010
- Author(s)
  平沢晃、赤羽智子、鶴田智彦、野村弘行、進伸幸、小崎健次郎、谷川原祐介、青木大輔
- Organizer
  第31回日本臨床薬理学会年会
- Place of Presentation
  京都
- Year and Date
  2010-12-02
- Data Source
  KAKENHI-PROJECT-22791545
[Presentation] Association between the UGT1A1 polymorphism, bilirubin levels, and dyslipidemia in endometrial cancer.2010
- Author(s)
  Matsumura S, Hirasawa A, Akahane T, et al
- Organizer
  AACR/JCA Joint Conference
- Place of Presentation
  Hawaii, USA
- Data Source
  KAKENHI-PROJECT-19791168
[Presentation] Association between the UGTlA1 polymorphism, dyslipidemia and endometrial cancer.2010
- Author(s)
  Hirasawa A, Akahane T, Matsumura S, et al
- Organizer
  AACR/JCA Joint Conference
- Place of Presentation
  Hawaii, USA
- Data Source
  KAKENHI-PROJECT-19791168
[Presentation] 卵巣明細胞腺癌におけるHNF1B発現特異性と臨床病理学的因子との関連に関する検討2010
- Author(s)
  赤羽智子、冨永英一郎、平沢晃、進伸幸、青木大輔
- Organizer
  第51回組織細胞化学会秋期大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22791545
[Presentation] Association between the UGT1A1 polymorphism, dyslipidemia and endometrial cancer risk.2010
- Author(s)
  A Hirasawa, T Akahane, D Aoki, et al.
- Organizer
  European Human Genetics Conference
- Place of Presentation
  Gothenburg, Sweden
- Data Source
  KAKENHI-PROJECT-22791545
[Presentation] Association between the UGT1A1 polymorphism, dyslipidemiaand endometrial cancer.2010
- Author(s)
  Hirasawa A, Akahane T, Matsumura S, et al
- Organizer
  AACR/JCA Joint Conference
- Place of Presentation
  Hawaii, USA
- Data Source
  KAKENHI-PROJECT-19791168
[Presentation] 卵巣明細胞腺癌におけるHNF1B発現特異性と臨床病理学的因子との関連に関する検討2010
- Author(s)
  赤羽智子、冨永英一郎、平沢晃、進伸幸、青木大輔
- Organizer
  第51回組織細胞化学会秋期大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22791545
[Presentation] Analysis of UGTlAl ^*6, ^*27, ^*28 and ^*60 polymorphism and serum bilirubin levels for individualized cancer therapy usingirinotecan.2009
- Author(s)
  Hirasawa A, Akahane T, Tsuruta T, et al
- Organizer
  The 4th Asian Confernce on Pharmacoepidemiology
- Place of Presentation
  Tainan, Taiwan
- Data Source
  KAKENHI-PROJECT-19791168
[Presentation] UGT1A1遺伝子多型と血清ビリルビン値およびイリノテカンの有害事象に関するゲノム薬理学的検討2009
- Author(s)
  平沢晃、赤羽智子、鶴田智彦, 他5名
- Organizer
  第54回日本人類遺伝学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19791168
[Presentation] Pharmacogenomic effects of UDP-glucuronosyltransferaselAlon irinotecan-induced drug reaction and serum bilirubinlevels.2009
- Author(s)
  Hirasawa A, Akahane T, Tsuruta T, et al
- Organizer
  2009 European Human Genetics Conference
- Place of Presentation
  Vienna, Austria
- Data Source
  KAKENHI-PROJECT-19791168
[Presentation] 子宮体がんにおけるマイクロRNAの発現プロファイリング2009
- Author(s)
  平沢晃、齋藤康一郎、赤羽智子, 他6名
- Organizer
  第46回日本婦人科腫瘍学会学術集会
- Place of Presentation
  新潟
- Year and Date
  2009-07-10
- Data Source
  KAKENHI-PROJECT-19791168
[Presentation] UGT1A1遺伝子多型とイリノテカンの有害事象およびグルクロン酸抱合能に関するゲノム薬理学的検討(高得点演題)2009
- Author(s)
  平沢晃、赤羽智子, 他10名
- Organizer
  第61回日本産科婦人科学会学術講演会
- Place of Presentation
  京都
- Year and Date
  2009-04-04
- Data Source
  KAKENHI-PROJECT-19791168
[Presentation] 子宮体癌腹腔細胞診の臨床的意義(シンポジウム)2009
- Author(s)
  冨永英一郎、進伸幸、平沢晃、赤羽智子, 他3名
- Organizer
  第50回日本臨床細胞学会総会
- Place of Presentation
  東京
- Year and Date
  2009-06-27
- Data Source
  KAKENHI-PROJECT-19791168
[Presentation] ファーマコゲノミクスの臨床応用を目指した新規遺伝子多型診断システムの確立2009
- Author(s)
  平沢晃、松村聡子、鶴田智彦、赤羽智子, 他6名
- Organizer
  第30回日本臨床薬理学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19791168
[Presentation] 子宮体癌における腹腔細胞診の臨床的意義と新規診断マーカーの検索2009
- Author(s)
  冨永英一郎、進伸幸、赤羽智子, 他4名
- Organizer
  第50回日本組織細胞化学会総会
- Place of Presentation
  滋賀
- Data Source
  KAKENHI-PROJECT-19791168
[Presentation] Analysis of UGT1A1 polymorphism and serum bilirubin levels for individualized cancer therapy using irinotecan.2009
- Author(s)
  Hirasawa A, Akahane T, Tsuruta T, et al
- Organizer
  The 4th Asian Confernce on Pharmacoepidemiology
- Place of Presentation
  Tainan, Taiwan
- Data Source
  KAKENHI-PROJECT-19791168
[Presentation] Effects of UGT1A1 polymorphism on irinotecan-induced drug reaction and serum bilirubin levels.2009
- Author(s)
  Hirasawa A, Akahane T, Tsuruta T, et al
- Organizer
  The 59th Annual Meeting of The American Society of Human Genetics
- Place of Presentation
  Hawaii, USA
- Data Source
  KAKENHI-PROJECT-19791168
[Presentation] UGTlAl遺伝子多型と血清ビリルビン値およびイリノテカンの有害事象に関するゲノム薬理学的検討2009
- Author(s)
  平沢晃、赤羽智子、鶴田智彦, 他5名
- Organizer
  第54回日本人類遺伝学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19791168
[Presentation] Pharmacogenomic effects of UDPglucuronosyltransferase1A1 on irinotecan -induced drug reaction and serum biliru bin levels.2009
- Author(s)
  Hirasawa A, Akahane T, Tsuruta T, et al
- Organizer
  2009 European Human Genet ics Conference
- Place of Presentation
  Vienna, Austria
- Data Source
  KAKENHI-PROJECT-19791168
[Presentation] Effects of UGTlAl polymorphism on irinotecan-induced drugreaction and serum bilirubin levels.2009
- Author(s)
  Hirasawa A, Akahane T, Tsuruta T, et al
- Organizer
  The 59th Annual Meeting of The American Society of Human Genetics
- Place of Presentation
  Hawaii, USA
- Data Source
  KAKENHI-PROJECT-19791168
[Presentation] アレイCGHによる子宮体癌関連遺伝子および薬剤感受性遺伝子の探索(ワークショップ)2009
- Author(s)
  鶴田智彦、平沢晃、赤羽智子, 他6名
- Organizer
  第50回日本臨床細胞学会総会
- Place of Presentation
  東京
- Year and Date
  2009-06-27
- Data Source
  KAKENHI-PROJECT-19791168
[Presentation] UGT1A1遺伝子多型と血清ビリルビン値の関連および婦人科イリノテカン療法副作用への関与に関する検討2008
- Author(s)
  平沢晃、赤羽智子, 他10名
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2008-10-29
- Data Source
  KAKENHI-PROJECT-19791168
[Presentation] UGT1A1遺伝子多型と血清ビリルビン値の関連および婦人科イリノテカン療法副作用への関与に関する検討2008
- Author(s)
  平沢晃、赤羽智子, 他10名
- Organizer
  第29回日本臨床薬理学会
- Place of Presentation
  東京
- Year and Date
  2008-12-13
- Data Source
  KAKENHI-PROJECT-19791168
[Presentation] UGTIA1遺伝子多型と血清ビリルビン値の関連および婦人科イリノテカン療法副作用への関与に関する検討2008
- Author(s)
  平沢晃、赤羽智子、他10名
- Organizer
  第29回日本臨床薬理学会
- Place of Presentation
  東京
- Year and Date
  2008-12-13
- Data Source
  KAKENHI-PROJECT-19791168

1. Hirasawa Akira (90296658)

# of Collaborated Projects: 3 results

# of Collaborated Products: 29 results
2. YAMAGAMI Wataru (30348718)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
3. 片岡史夫 (40306824)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
4. NISHIO Kazuto (10208134)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. Eichirou Tominaga (80276328)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
6. 杉本昌弘 (30458963)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. NOMURA Hiyoyuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Akahane Tomoko 赤羽 智子

赤羽 智子 アカハネ トモコ

AKAHANE Tomoko 赤羽 智子

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Carcinogenic mechanism analysis and establishment new method at early detection of ovarian cancerPrincipal Investigator

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卵巣癌オルガノイドとドライバージーン解析に基づいた難治性卵巣癌個別化治療法の確立

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Carcinogenic mechanism of ovarian cancer and of examination of ovarian cancer by NGS analysisPrincipal Investigator

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Identification of factors related to penetrance and predictive model for ovarian cancer among BRCA1or BRCA2 mutation carriers

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Mechanism of ovarian cancer carcinogenesis from fallopian tube epithelial cellsPrincipal Investigator

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Towards precision medicine for ovarian cancer using drug sensitivity and resistance testing and genomic analysis

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The origin of ovarian clear cell carcinoma and endometrioid carcinoma malignant transformation from endometriosisPrincipal Investigator

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Identification of novel bio-marker associated with drug response in ovarian cancer

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The mechanism of carcinogenesis in ovarian clear cellcarcinoma and ovarian endometrioid carcinoma from endometriosis.Principal Investigator

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The mechanism of carcinogenesis in ovarian clear cell carcinoma and ovarian endometrioid carcinoma from endometriosis.Principal Investigator

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子宮内膜症の卵巣明細胞癌、類内膜腺癌への悪性化メカニズムの解明Principal Investigator

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[Journal Article] 遺伝性腫瘍2023

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[Journal Article] Patient-derived ovarian cancer organoids capture the genomic profiles of primary tumours applicable for drug sensitivity and resistance testing2020

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DOI

Akahane Tomoko 赤羽智子

赤羽智子アカハネトモコ

AKAHANE Tomoko 赤羽智子