Waku Yuka 和久由佳 (仲島由佳)

… Alternative Names

仲島由佳

NAKAJIMA Yuka 仲島由佳

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Researcher Number	40399499
Affiliation (Current)	2025: 公益財団法人神戸医療産業都市推進機構, その他部局等, 研究員
Affiliation (based on the past Project Information) *help	2021 – 2023: 公益財団法人神戸医療産業都市推進機構, その他部局等, 研究員 2017 – 2020: 京都大学, 医学研究科, 研究員 2014 – 2015: 筑波大学, 生命環境系, 助教 2011 – 2012: 筑波大学, 生命環境系, 助教
Review Section/Research Field	Principal Investigator Basic Section 49070:Immunology-related / Basic Section 50010:Tumor biology-related / Tumor biology / Medical genome science / Biological pharmacy Except Principal Investigator Biological Sciences
Keywords	Principal Investigator 免疫老化 / PD-1 / 腫瘍免疫 / T細胞 / 抗腫瘍免疫 / 老化 / １炭素代謝 / CD8陽性細胞 / 塩基メチル化 / rRNA … More / DNAオリゴヌクレオチド / 転写 / KLF5 / エストロゲン受容体ベータ（ERb) / 分子生物学 / エストロゲン受容体 / 腫瘍形成 / 血管新生 … More Except Principal Investigator p53 / Nucleomethylin / Mybbpla / Ｘ線小角散乱 / Ｘ線結晶解析 / Smad / ビタミンDレセプター / X線小角散乱 / Ｘ線結晶構造解析 / 核内受容体 / Roquin / X線結晶解析 / アルギニンメチル化酵素 / X線結晶構造解析 / SAM / 翻訳後修飾 / PRMT / アルギニンメチル化 Less

CD45の発現変動を介した老化T細胞の機能抑制メカニズムの解明Principal Investigator
- Principal Investigator
  
  和久由佳 (仲島由佳)
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49070:Immunology-related
- Research Institution
  Foundation for Biomedical Research and Innovation at Kobe
The mechanism of age-related unresponsiveness to PD-1 blockade cancer therapyPrincipal Investigator
- Principal Investigator
  
  Waku Yuka
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Foundation for Biomedical Research and Innovation at Kobe
  Kyoto University
Analysis of rRNA methylation in tumor immune system though PD-1Principal Investigator
- Principal Investigator
  
  Waku Yuka
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor biology
- Research Institution
  Kyoto University
Mechanistic analysis and application of novel activation technique for regenerative medicinePrincipal Investigator
- Principal Investigator
  
  NAKAJIMA Yuka
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Medical genome science
- Research Institution
  University of Tsukuba
Study on the mechanism of anti-angiogenesis and tumorigenesis through genomic function of nuclear receptorPrincipal Investigator
- Principal Investigator
  
  NAKAJIMA Yuka
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  University of Tsukuba
Structural analysis of the transcription environment factors that engage in crosstalk with metabolic pathways
- Principal Investigator
  
  Shimizu Toshiyuki
- Project Period (FY)
  2011 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo

All 2023 2022 2021 2019 2018 2017 2015 2013 2012 2011 Other

All Journal Article Presentation Book

[Book] 実験医学　特集　炎症老化　Inflammaging「T細胞老化と炎症のつながり」2023
- Author(s)
  仲島由佳、茶本健司
- Total Pages
  6
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-23K06591
[Book] 実験医学「がん微小環境におけるサイトカインを介した免疫制御」2021
- Author(s)
  仲島由佳、茶本健司
- Total Pages
  5
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-20K07615
[Book] Trends in Cancer Immunology2019
- Author(s)
  仲島由佳、茶本健司、河上裕
- Total Pages
  4
- Publisher
  メディカルビュー社
- Data Source
  KAKENHI-PROJECT-17K07164
[Book] がん分子標的治療　分子標的薬の新しいバイオマーカー2018
- Author(s)
  仲島由佳、茶本健司
- Total Pages
  4
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-17K07164
[Book] THE LUNG perspectives　特集：免疫学の新展開と呼吸器疾患2017
- Author(s)
  仲島由佳、波多江龍亮、茶本健司
- Total Pages
  5
- Publisher
  メディカルビュー社
- Data Source
  KAKENHI-PROJECT-17K07164
[Book] がん基盤生物学-革新的シーズ育成に向けて-2013
- Author(s)
  仲島由佳、和久剛、柳澤純
- Total Pages
  8
- Publisher
  (財)金原一郎記念医学医療振興財団/医学書院
- Data Source
  KAKENHI-PROJECT-23790075
[Book] がん基盤生物学―革新的シーズ育成に向けて―2013
- Author(s)
  仲島由佳
- Total Pages
  8
- Publisher
  株式会社　南山堂
- Data Source
  KAKENHI-PROJECT-23790075
[Book] 細胞核―構造と機能2011
- Author(s)
  仲島由佳、山口智絵、石川寛子、柳澤純
- Total Pages
  2
- Publisher
  （財）金原一郎記念医学医療振興財団/医学書院
- Data Source
  KAKENHI-PROJECT-23790075
[Book] 細胞核-構造と機能2011
- Author(s)
  仲島由佳、山口智絵、石川寛子、柳澤純
- Total Pages
  2
- Publisher
  (財)金原一郎記念医学医療振興財団/医学書院
- Data Source
  KAKENHI-PROJECT-23790075
[Journal Article] Spermidine activates mitochondrial trifunctional protein and improves antitumor immunity in mice.2022
- Author(s)
  Al-Habsi M, Chamoto K, Matsumoto K, Nomura N, Zhang B, Sugiura Y, Sonomura K, Maharani A, Nakajima Y, Wu Y, Nomura Y, Menzies R, Tajima M, Kitaoka K, Haku Y, Delghandi S, Yurimoto K, Matsuda F, Iwata S, Ogura T, Fagarasan S, Honjo T.
- Journal Title
  
  Science
  
  Volume: 378 Issue: 6618
- DOI
  10.1126/science.abj3510
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K20592, KAKENHI-PROJECT-19H00923, KAKENHI-PROJECT-20K07615, KAKENHI-PLANNED-19H05777
[Journal Article] Critical role of the CD44lowCD62Llow CD8+ T cell subset in restoring antitumor immunity in aged mice2021
- Author(s)
  Yuka Nakajima, Kenji Chamoto, Takuma Oura, and Tasuku Honjo
- Journal Title
  
  PNAS
  
  Volume: 118 Issue: 23
- DOI
  10.1073/pnas.2103730118
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07615
[Journal Article] Inherited PD-1 deficiency underlies tuberculosis and autoimmunity in a child2021
- Author(s)
  Masato Ogishi, Rui Yang, Caner Aytekin, ~ Yuka Nakajima et al.
- Journal Title
  
  Nat. Med.
  
  Volume: 27 Issue: 9 Pages: 1646-1654
- DOI
  10.1038/s41591-021-01388-5
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07615
[Journal Article] Nucleomethylin deficiency impairs embryonic erythropoiesis2018
- Author(s)
  Murakami Shohei、Suzuki Takuma、Yokoyama Wataru、Yagi Satoko、Matsumura Keita、Nakajima Yuka、Harigae Hideo、Fukamizu Akiyoshi、Motohashi Hozumi
- Journal Title
  
  J. Biochem.
  
  Volume: 印刷中 Issue: 5 Pages: 413-423
- DOI
  10.1093/jb/mvx086
- NAID
  40021555326
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H01519, KAKENHI-PROJECT-15H04692, KAKENHI-PUBLICLY-18H04794, KAKENHI-PROJECT-18H02621, KAKENHI-PROJECT-17F17116, KAKENHI-PROJECT-17K19508, KAKENHI-PROJECT-17K07164
[Presentation] 免疫老化の機構と改善への試み2023
- Author(s)
  仲島由佳
- Organizer
  筑波大学開学５０周年記念　TARAシンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-23K06591
[Presentation] 老化マウスT細胞ミトコンドリア不全による抗腫瘍免疫力の低下とその制御法の開発2021
- Author(s)
  茶本健司, 仲島由佳, 本庶佑
- Organizer
  Agilent 細胞解析ウェブナーシリーズ2021
- Data Source
  KAKENHI-PROJECT-20K07615
[Presentation] 老化によるがん免疫抑制機構の解明とその解除法の開発2021
- Author(s)
  茶本健司, 仲島由佳, 本庶佑
- Organizer
  第２５回日本がん免疫学会総会
- Data Source
  KAKENHI-PROJECT-20K07615
[Presentation] CD45 Modulation Recovers Resistance to PD-1 Blockade Cancer Immunotherapy2021
- Author(s)
  Sara Delghandi, Kenji Chamoto, Yuka Nakajima, Tasuku Honjo
- Organizer
  The 50th Annual Meeting of the Japanese Society for Immunology
- Data Source
  KAKENHI-PROJECT-20K07615
[Presentation] A combinational strategy for unresponsiveness to PD-1 blockade therapy in aged individuals2021
- Author(s)
  Chamoto K, Nakajima Y, Honjo T
- Organizer
  The 80th Annual Meeting of the Japanese Cancer Association
- Data Source
  KAKENHI-PROJECT-20K07615
[Presentation] Age-related resistance to PD-1 blockade therapy through reduction of a specific CD8+ T-cell subpopulation2019
- Author(s)
  Yuka Nakajima, Kenji Chamoto, Tasuku Honjo
- Organizer
  第７８回日本癌学会
- Data Source
  KAKENHI-PROJECT-17K07164
[Presentation] オリゴDNAを用いた内在遺伝子の転写活性化2015
- Author(s)
  仲島由佳
- Organizer
  文部科学省「新学術領域」生命素子による転写環境とエネルギー代謝のクロストーク制御「転写システム」領域班会議
- Place of Presentation
  ユウベルホテル　熊本県熊本市
- Year and Date
  2015-06-14
- Data Source
  KAKENHI-PROJECT-26830130
[Presentation] Structural basis for vitamin D receptor antagonistic mechanism by 1α, 25-dihydroxyvitamin D3-26, 23-lactams (DLAMs)2013
- Author(s)
  Asano L, Ito I, Waku T, Nagasawa K, Yanagisawa J, Shimizu T
- Organizer
  ICSG2013-SLS
- Place of Presentation
  札幌（北海道）
- Data Source
  KAKENHI-PLANNED-23116007
[Presentation] ERβのノンクラシカル経路の前立腺癌進行における役割2012
- Author(s)
  仲島由佳、刑部朝実、石川寛子、赤荻健介、柳澤純
- Organizer
  転写代謝システム・転写研究会共催「若手ワークショップ@湯河原」
- Place of Presentation
  湯河原
- Year and Date
  2012-02-10
- Data Source
  KAKENHI-PROJECT-23790075
[Presentation] エストロゲン受容体の新規ノンクラシカル経路を介した前立腺癌治療の可能性2012
- Author(s)
  仲島由佳
- Organizer
  第14回 UTPシンポジウム
- Place of Presentation
  東京
- Year and Date
  2012-01-15
- Data Source
  KAKENHI-PROJECT-23790075
[Presentation] 新規核内授与体制御機構に基づいた腎性骨症治療薬の開発2012
- Author(s)
  仲島由佳
- Organizer
  第5回慢性腎臓病病態研究会
- Place of Presentation
  東京
- Year and Date
  2012-07-28
- Data Source
  KAKENHI-PROJECT-23790075
[Presentation] KLF5-ERb; pathway is responsible for the contradictory effects of estrogen on prostate tumor formation2011
- Author(s)
  Asami Osakabe, Hiroko Ishikawa, Yuka Nakajima, Junn Yanagisawa
- Organizer
  第３４回　日本分子生物学会年会
- Place of Presentation
  横浜、パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23790075
[Presentation] Estrogen receptor ligands regulate prostate tumorformation through a nonclassical pathway that includes ERβ and KLF52011
- Author(s)
  Yuka Nakajima et al
- Organizer
  The EMBO meeting 2011
- Place of Presentation
  オーストリア
- Year and Date
  2011-09-11
- Data Source
  KAKENHI-PROJECT-23790075
[Presentation] A novel ER antagonist suppresses prostate tumor growth by inhibiting ERβ-KLF5 pathway without estrogenic action2011
- Author(s)
  Hiroko Ishikawa, Yuka Nakajima, Junn Yanagisawa
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2011-12-14
- Data Source
  KAKENHI-PROJECT-23790075
[Presentation] KLF5-ERβ pathway is responsible for the biphasic effects of estrogen on prostate tumor growth2011
- Author(s)
  Yuka Nakajima et al.
- Organizer
  70^<th>Annual Meeting of Japanese Cancer Association
- Place of Presentation
  名古屋
- Year and Date
  2011-10-04
- Data Source
  KAKENHI-PROJECT-23790075
[Presentation] KLF5-ERβ pathway is responsible for the contradictory effects of estrogen on prostate tumor formation2011
- Author(s)
  Asami Osakabe, Yuka Nakajima, Hiroko Ishikawa, Junn Yanagisawa
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2011-12-14
- Data Source
  KAKENHI-PROJECT-23790075
[Presentation] KLF5-ERb pathway is responsible for the contradictory effects of estrogen on prostate tumor formation2011
- Author(s)
  Hiroko Ishikawa, Asami Osakabe, Yuka Nakajima, Junn Yanagisawa
- Organizer
  第３４回　日本分子生物学会年会
- Place of Presentation
  横浜、パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23790075
[Presentation] KLF5-ERβ pathway is responsible for the contradictory effects of estrogen on prostate tumor growth2011
- Author(s)
  Asami Osakabe,Yuka Nakajima et al
- Organizer
  The EMBO meeting 2011
- Place of Presentation
  オーストリア
- Year and Date
  2011-09-11
- Data Source
  KAKENHI-PROJECT-23790075
[Presentation] KLF5-ERb; pathway is responsible for the biphasic effects of estrogen on prostate tumor growth
- Author(s)
  Yuka Nakajima, Asami Osakabe, Chie Yamaguchi, Junn Yanagisawa
- Organizer
  70th Annual Meeting of Japanese Cancer Association
- Place of Presentation
  名古屋、名古屋国際会議場
- Data Source
  KAKENHI-PROJECT-23790075
[Presentation] エストロゲン受容体の新規ノンクラシカル経路を介した前立腺癌治療の可能性
- Author(s)
  仲島由佳
- Organizer
  第１４回　ＵＴＰシンポジウム(招待講演)
- Place of Presentation
  東京、椿山荘
- Data Source
  KAKENHI-PROJECT-23790075
[Presentation] Estrogen receptor ligands regulate prostate tumor formation through a nonclassical pathway that includes ERb and KLF5
- Author(s)
  Yuka Nakajima, Kensuke Akaogi, Asami Osakabe, Chie Yamaguchi, Hiroko Ishikawa, Junn Yanagisawa
- Organizer
  The EMBO meeting 2011
- Place of Presentation
  オーストリア
- Data Source
  KAKENHI-PROJECT-23790075
[Presentation] 新規核内受容体制御機構に基づいた腎性骨症治療薬の開発
- Author(s)
  仲島由佳
- Organizer
  第５回慢性腎臓病病態研究会
- Place of Presentation
  東京　経団連会館
- Invited
- Data Source
  KAKENHI-PROJECT-23790075

1. Shimizu Toshiyuki (30273858)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
2. TOMA Sachiko (40363535)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 深水昭吉

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 小椋利彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Waku Yuka 和久 由佳 (仲島 由佳)

仲島由佳

NAKAJIMA Yuka 仲島 由佳

Research Projects

Research Products

Co-Researchers

CD45の発現変動を介した老化T細胞の機能抑制メカニズムの解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The mechanism of age-related unresponsiveness to PD-1 blockade cancer therapyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of rRNA methylation in tumor immune system though PD-1Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Mechanistic analysis and application of novel activation technique for regenerative medicinePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study on the mechanism of anti-angiogenesis and tumorigenesis through genomic function of nuclear receptorPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Structural analysis of the transcription environment factors that engage in crosstalk with metabolic pathways

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Book] 実験医学 特集 炎症老化 Inflammaging「T細胞老化と炎症のつながり」2023

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[Book] 実験医学「がん微小環境におけるサイトカインを介した免疫制御」2021

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[Book] Trends in Cancer Immunology2019

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[Book] がん分子標的治療 分子標的薬の新しいバイオマーカー2018

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Data Source

[Book] THE LUNG perspectives 特集：免疫学の新展開と呼吸器疾患2017

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Total Pages

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Data Source

[Book] がん基盤生物学-革新的シーズ育成に向けて-2013

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[Book] がん基盤生物学―革新的シーズ育成に向けて―2013

Author(s)

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[Book] 細胞核―構造と機能2011

Author(s)

Total Pages

Waku Yuka 和久由佳 (仲島由佳)

NAKAJIMA Yuka 仲島由佳

[Book] 実験医学　特集　炎症老化　Inflammaging「T細胞老化と炎症のつながり」2023

[Book] がん分子標的治療　分子標的薬の新しいバイオマーカー2018

[Book] THE LUNG perspectives　特集：免疫学の新展開と呼吸器疾患2017