Horibata Katsuyoshi 堀端克良

… Alternative Names

堀端克良ホリバタカツヨシ

HORIBATA Katsuyoshi 堀端克良

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Researcher Number	40402995
Affiliation (Current)	2022: 国立医薬品食品衛生研究所, 変異遺伝部, 室長
Affiliation (based on the past Project Information) *help	2020 – 2021: 国立医薬品食品衛生研究所, 変異遺伝部, 室長 2017 – 2020: 国立医薬品食品衛生研究所, 変異遺伝部, 主任研究官 2015: 国立医薬品食品衛生研究所, 変異遺伝部, 研究員 2014: 国立医薬品食品衛生研究所, 変異遺伝部, 主任研究官 2010 – 2011: 国立医薬品食品衛生研究所, 変異遺伝部, 主任研究官 … More 2009: 大阪大学, 大学院・生命機能研究科, 助教 2007: Osaka University, 大学院・生命機能研究科, 助教 2006: 大阪大学, 大学院生命機能研究科, 助手 Less
Review Section/Research Field	Principal Investigator Risk sciences of radiation and chemicals / Human genetics / Risk sciences of radiation/Chemicals / Molecular biology / Basic Section 63030:Chemical substance influence on environment-related Except Principal Investigator Human genetics / Basic Section 63030:Chemical substance influence on environment-related
Keywords	Principal Investigator DNA修復 / 転写 / DNA損傷 / 突然変異 / コケイン症候群 / 早老症 / コケイン症候 / 修復 / ゲノム / プロテオーム … More / 放射線 / topoisomerase / 複合体 / 内在性DNA損傷 / 脊髄小脳失調症 / DNAトポロジー / ＤＮＡ修復 / 遺伝毒性 / 免疫 … More Except Principal Investigator 色素性乾皮症 / コケイン症候群 / DNA修復 / 転写 / 転写と共役した修復 / ユビキチンリガーゼ / RNAポリメラーゼII / 微小核融合法 / XPD / CGH array / ユビキチン化 / ホルモン受容体 / 色素性幹皮症 / ユビキチン・リガーゼ / XPG / TFIIH / CAK / ホルモンレセプター / TFIIS / UV^s症候群 / 酸化的DNA損傷 / 微小核融合 / 遺伝毒性 / 次世代影響 / DNA損傷 / 遺伝子突然変異 / ゲノム / アクリルアミド / 生殖細胞 / 生殖細胞突然変異 / DNA付加体 Less

遺伝情報発現と遺伝子突然変異の相関Principal Investigator
- Principal Investigator
  
  堀端克良
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 63030:Chemical substance influence on environment-related
- Research Institution
  National Institute of Health Sciences
A study on DNA damages in germ cells of male mice and germline mutations induced in the offspring
- Principal Investigator
  
  増村健一
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 63030:Chemical substance influence on environment-related
- Research Institution
  National Institute of Health Sciences
Analysis of mutagenesis relating to DNA topology, transcription and DNA repairPrincipal Investigator
- Principal Investigator
  
  Horibata Katsuyoshi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Risk sciences of radiation and chemicals
- Research Institution
  National Institute of Health Sciences
Analysis of DNA topology, transcription and DNA repairPrincipal Investigator
- Principal Investigator
  
  Horibata Katsuyoshi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Molecular biology
  Risk sciences of radiation and chemicals
- Research Institution
  National Institute of Health Sciences
Comprehensive analyses of DNA Topoisomerase I and relating DNA repairPrincipal Investigator
- Principal Investigator
  
  HORIBATA Katsuyoshi
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  National Institute of Health Sciences
コケイン症候群B群で見られる早期老化症状発症システムの解析Principal Investigator
- Principal Investigator
  
  堀端克良
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (Start-up)
- Research Field
  
  Human genetics
- Research Institution
  Osaka University
Molecular genetic analysis of cellular response to transcription-blocking DNA damage and its defective disorders
- Principal Investigator
  
  TANAKA Kiyoji
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Human genetics
- Research Institution
  Osaka University

All 2021 2019 2018 2016 2015 2014 2012 2011 2010 2009 2008 2007 Other

All Journal Article Presentation

[Journal Article] Development of a new quantitative structure?activity relationship model for predicting Ames mutagenicity of food flavor chemicals using StarDrop? auto-Modeller?2021
- Author(s)
  Kasamatsu Toshio、Kitazawa Airi、Tajima Sumie、Kaneko Masahiro、Sugiyama Kei-ichi、Yamada Masami、Yasui Manabu、Masumura Kenichi、Horibata Katsuyoshi、Honma Masamitsu
- Journal Title
  
  Genes and Environment
  
  Volume: 43 Pages: 16-16
- DOI
  10.1186/s41021-021-00182-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K12347
[Journal Article] In vivo and in vitro mutagenicity of perillaldehyde and cinnamaldehyde2021
- Author(s)
  Honma Masamitsu、Yamada Masami、Yasui Manabu、Horibata Katsuyoshi、Sugiyama Kei-ichi、Masumura Kenichi
- Journal Title
  
  Genes and Environment
  
  Volume: 43 Pages: 30-30
- DOI
  10.1186/s41021-021-00204-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K12347
[Journal Article] In vivo genotoxicity testing strategies: Report from the 7th International Workshop on Genotoxicity Testing (IWGT)2019
- Author(s)
  Kirkland D, Uno Y, Luijten M, Beevers C, van Benthem J, Burlinson B, Dertinger S, Douglas GR, Hamada S, Horibata K, Lovell DP, Manjanatha M, Martus HJ, Mei N, Morita T, Ohyama W, Williams A
- Journal Title
  
  Mutation Research
  
  Volume: in press
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K00566
[Journal Article] Standard protocol for the total red blood cell Pig-a assay used in the interlaboratory trial organized by the Mammalian Mutagenicity Study Group of the Japanese Environmental Mutagen Society.2018
- Author(s)
  Chikura S, Kimoto T, Itoh S, Sanada H, Muto S, Horibata K
- Journal Title
  
  Genes and Environment
  
  Volume: 41 Pages: 5-5
- DOI
  10.1186/s41021-019-0121-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K00566
[Journal Article] Measuring Reproducibility of Dose Response Data for the Pig-a Assay using Covariate Benchmark Dose Analysis.2016
- Author(s)
  Johnson GE, Yamamoto M, Suzuki Y, Adachi H, Kyoya T, Takasawa H, Horibata K, Tsutsumi E, Wada K, Kikuzuki R, Yoshida I, Kimoto T, Maeda A, Narumi K
- Journal Title
  
  Mutation Research
  
  Volume: in press
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26870867
[Journal Article] Evaluation of mutagenicity of acrylamide using RBC Pig-a and PIGRET assays by single peroral dose in rats.2016
- Author(s)
  Horibata K, Ukai A, Honma M
- Journal Title
  
  Mutation Research
  
  Volume: in press
- DOI
  10.1016/j.mrgentox.2015.12.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26870867
[Journal Article] The in vivo Pig-a assay: A report of the International Workshop On Genotoxicity Testing (IWGT) Workgroup.2015
- Author(s)
  Gollapudi BB, Lynch AM, Heflich RH, Dertinger SD, Dobrovolsky VN, Froetschl R, Horibata K, Kenyon MO, Kimoto T, Lovell DP, Stankowski Jr LF, White PA, Witt KL, Tanir JY.
- Journal Title
  
  Mutation Research
  
  Volume: in press Pages: 23-35
- DOI
  10.1016/j.mrgentox.2014.09.007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26870867
[Journal Article] Constructive rescue of TFIIH instability by an alternative isoform of XPD derived from a mutated XPD allele in mild but not severe XP-D/CS.2015
- Author(s)
  Katsuyoshi Horibata, Sayaka Kono, Chie Ishigami, Xue Zhang, Madoka Aizawa, Yuko Kako, Takuma Ishii, Rika Kosaki, Masafumi Saijo and Kiyoji Tanaka
- Journal Title
  
  J Hum Genet.
  
  Volume: 印刷中 Pages: 259-265
- DOI
  10.1038/jhg.2015.18
- NAID
  40020462586
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-22131009, KAKENHI-PROJECT-26870867
[Journal Article] Evaluation of Rats' In Vivo Genotoxicity Induced by N-ethyl-N-nitrosourea in the RBC Pig-a, PIGRET, and gpt Assays2014
- Author(s)
 Horibata K, Ukai A, Honma M.
- Journal Title
 
 Genes and Environment
 
 Volume: 36 Issue: 4 Pages: 199-202
- DOI
 10.3123/jemsge.2014.023
- NAID
 130004685140
- ISSN
 1880-7046, 1880-7062
- Language
 English
- Peer Reviewed
- Data Source
 KAKENHI-PROJECT-26870867
[Journal Article] Absence of in vivo genotoxicity of 3-monochloropropane-1,2-diol and associated fatty acid esters in a 4-week comprehensive toxicity study using F344 gpt delta rats.2014
- Author(s)
  Onami S, Cho YM, Toyoda T, Horibata K, Ishii Y, Umemura T, Honma M, Nohmi T, Nishikawa A, Ogawa K
- Journal Title
  
  Mutagenesis
  
  Volume: 29 Pages: 295-302
- DOI
  10.1093/mutage/geu018
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26430132, KAKENHI-PROJECT-26870867
[Journal Article] Nucleotide excision repair-dependent DNA double-strand break formation and ATM signaling activation in mammalian quiescent cells.2014
- Author(s)
  Mitsuo Wakasugi, Takuma Sasaki, Megumi Matsumoto, Miyuki Nagaoka, Keiko Inoue, Manabu Inobe, Katsuyoshi Horibata, Kiyoji Tanaka, and Tsukasa Matsunaga
- Journal Title
  
  The Journal of biological chemistry
  
  Volume: 289 Pages: 28730-28737
- DOI
  10.1074/jbc.m114.589747
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-22131009, KAKENHI-PROJECT-24510068, KAKENHI-PROJECT-25281017, KAKENHI-PROJECT-25640089, KAKENHI-PROJECT-26870867
[Journal Article] The conserved Cockayne syndrome B-piggyBac fusion protein(CSB-PGBD3) affects DNA repair and induces both interferon-like and innate antiviral responses in CSB-null cells2012
- Author(s)
  Arnold D. Bailey, Lucas T. Gray, Thomas Pavelitz, John C. Newman, Katsuyoshi Horibata, Kiyoji Tanaka and Alan M. Weiner
- Journal Title
  
  DNA repair
  
  Volume: 11(5) Pages: 488-501
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22710061
[Journal Article] Mutations in UVSSA cause UV-sensitive syndrome and destabilize ERCC6 in transcription-coupled DNA repair.2012
- Author(s)
  X. Zhang
- Journal Title
  
  Nat Genet
  
  Volume: 44 Pages: 593-597
- DOI
  10.1038/ng.2228
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22241016, KAKENHI-PROJECT-22710061, KAKENHI-PROJECT-23300363, KAKENHI-PROJECT-23510059, KAKENHI-PLANNED-22131009
[Journal Article] these authors contributed equally to this work. Mutations in UVSSA cause UV-sensitive syndrome and destabilize ERCC6 in transcription-coupled DNA repair2012
- Author(s)
  Xue Zhang, Katsuyoshi Horibata, Masafumi Saijo, Chie Ishigami, Akiko Ukai, Shin-ichiro Kanno, Hidetoshi Tahara, Edward G Neilan, Masamitsu Honma, Takehiko Nohmi, Akira Yasui and Kiyoji Tanaka
- Journal Title
  
  Nature Genetics
  
  Volume: 44(5) Pages: 593-597
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22710061
[Journal Article] Further Development of the Rat Pig-a Mutation Assay : Measuring Rat Pig-a Mutant Bone Marrow Erythroids and a High Throughput Assay for Mutant Peripheral Blood Reticulocytes2011
- Author(s)
  Takafumi Kimoto, Satsuki Chikura, Kumiko Suzuki, Xiao mei Kobayashi, Yasuhiro Itano, Katsuyoshi Horibata, Masamitsu Honma, Vasily N. Dobrovolsky, Robert H. Heflich, Daishiro Miura and Yoshinori Kasahara
- Journal Title
  
  Environmental and Molecular Mutagenesis
  
  Volume: 52 Pages: 774-783
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22710061
[Journal Article] Mutant Cockayne syndrome group B protein inhibits repair of DNA topoisomerase I-DNA covalent complex2011
- Author(s)
  Katsuyoshi Horibata, Masafumi Saijo, Mui Nee Bay, Li Lan, Isao Kuraoka, Philip J. Brooks, Masamitsu Honma, Takehiko Nohmi, Akira Yasui and Kiyoji Tanaka
- Journal Title
  
  Genes to Cells
  
  Volume: 16(1) Pages: 101-14
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22710061
[Journal Article] Fullerene (C60) is negative in the in vivo Pig-A gene mutation assay2011
- Author(s)
  Horibata, K., et al.
- Journal Title
  
  Genes and Environment
  
  Volume: 33 Pages: 27-31
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22710061
[Journal Article] Fullerene(C60) is negative in the in vivo Pig-A gene mutation assay2011
- Author(s)
  Katsuyoshi Horibata, Akiko Ukai, Naoki Koyama, Atsuya Takagi, Jun Kanno, Takafumi Kimoto, Daishiro Miura, Akihiko Hirose, and Masamitsu Honma
- Journal Title
  
  Genes and Environment
  
  Volume: 33(1) Pages: 27-31
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22710061
[Journal Article] Mutant Cockayne syndrome group B protein inhibits repair of DNA topoisomerase I-DNA covalent complex2011
- Author(s)
  Horibata, K., et al.
- Journal Title
  
  Genes to Cells
  
  Volume: 16 Pages: 101-114
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22710061
[Journal Article] Roles of RecA protein in spontaneous mutagenesis in Escherichia coli.2007
- Author(s)
  Katsuyoshi Horibata
- Journal Title
  
  Genes & Genetic Systems 82
  
  Pages: 99-108
- NAID
  10024393945
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18890099
[Presentation] Pig-a アッセイの標準化に関する研究:バリデーション研究の推進とヒトへの適用2018
- Author(s)
  堀端克良
- Organizer
  日本環境変異原学会第47回大会
- Data Source
  KAKENHI-PROJECT-17K00566
[Presentation] Pig-a アッセイ2018
- Author(s)
  堀端克良
- Organizer
  哺乳動物試験研究会第73回定例会
- Data Source
  KAKENHI-PROJECT-17K00566
[Presentation] Pig-a 試験2018
- Author(s)
  堀端克良
- Organizer
  哺乳動物試験研究会第72回定例会
- Data Source
  KAKENHI-PROJECT-17K00566
[Presentation] Pig-a / PIG-A遺伝子変異試験によるヒトを含めたin vivo遺伝毒性モニタリング2018
- Author(s)
  堀端克良
- Organizer
  平成30年度日本環境変異原学会公開シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-17K00566
[Presentation] 共同研究報告I:Pig-a アッセイ2015
- Author(s)
  堀端克良
- Organizer
  哺乳動物試験研究会第66回定例会
- Place of Presentation
  栃木
- Year and Date
  2015-06-12
- Data Source
  KAKENHI-PROJECT-26870867
[Presentation] Interlaboratory Trial of the PIGRET Assay As a Short-term Genotoxicity Test: Collaborative Study by Mammalian Mutagenicity Study (MMS) Group of Japanese Environmental Mutagen Society (JEMS)2015
- Author(s)
  Horibata K, Yamada M, Ukai A, Kimoto T, Chikura S, Miura D, Itoh S, Muto S, Uno Y, Sanada H, Takashima R, Shigano M, Takasawa H, Hamada S, Yamamoto M, Hori H, Tsutsumi E, Wada K, Maeda A, Kikuzuki R, Ogiwara Y, Kyoya T, Adachi H, Uematsu Y, Yoshida I, Narumi K, Fujiishi Y, Fukuda T, Suzuki Y, Goto K, Morita T, Honma M
- Organizer
  Environmental Mutagen Society 46th Annual Meeting
- Place of Presentation
  New Orleans, Louisiana, USA
- Year and Date
  2015-09-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26870867
[Presentation] Pig-a アッセイ2015
- Author(s)
  堀端克良
- Organizer
  哺乳動物試験研究会第67回定例会
- Place of Presentation
  福岡
- Year and Date
  2015-11-26
- Data Source
  KAKENHI-PROJECT-26870867
[Presentation] Pig-a/PIGRETアッセイの短期試験としての有用性：MMS共同研究報告2015
- Author(s)
  堀端克良, 山田雅巳, 鵜飼明子, 木本崇文, 千藏さつき, 三浦大志郎, 伊東悟, 武藤重治, 宇野芳文, 真田尚和, 高島理恵,志賀野美幸,高沢博修, 濵田修一,山本美佳, 堀妃佐子, 堤絵梨, 和田邦生, 前田晃央, 菊月隆太, 荻原庸介, 京谷恭弘, 足立秀樹, 上松泰明, 吉田唯真, 成見香瑞範, 藤石洋平,福田隆之, 鈴木裕太, 後藤玄, 森田健, 本間正充
- Organizer
  日本環境変異原学会第44回大会
- Place of Presentation
  福岡
- Year and Date
  2015-11-27
- Data Source
  KAKENHI-PROJECT-26870867
[Presentation] 共同研究報告I:Pig-a assay 進捗状況報告2014
- Author(s)
  堀端克良
- Organizer
  哺乳動物試験研究会第65回定例会
- Place of Presentation
  東京
- Year and Date
  2014-12-03
- Data Source
  KAKENHI-PROJECT-26870867
[Presentation] Evaluation of in vivo genotoxicity induced by N-ethyl-N-nitrosourea, benzo[a] pyrene and 4-nitroquinoline-1-oxide by Pig-a and gpt assays2012
- Author(s)
  Katsuyoshi Horibata, Akiko Ukai, Takafumi Kimoto, Tetsuya Suzuki, Nagisa Kamoshita, Kenichi Masumura, Takehiko Nohmi and Masamitsu Honma
- Organizer
  Society of Toxicology 51st Annual Meeting
- Place of Presentation
  San Francisco
- Year and Date
  2012-03-15
- Data Source
  KAKENHI-PROJECT-22710061
[Presentation] Evaluation of in vivo genotoxicity induced by N-ethyl-N-nitrosourea, benzo[a]pyrene and 4-nitroquinoline-1-oxide by Pig-a and gpt assays2012
- Author(s)
  Horibata, K., et.al.
- Organizer
  Society of Toxicology 51st Annual Meeting
- Place of Presentation
  サンフランシスコ
- Year and Date
  2012-03-15
- Data Source
  KAKENHI-PROJECT-22710061
[Presentation] glycidolと3-MCPD及びこれらのエステル化合物におけるラット28日間反復投与試験の影響について2012
- Author(s)
  大波冴子,曹永晩,豊田武士,堀端克良,本間正充,能美健彦,西川秋佳,小川久美子
- Organizer
  第28回日本毒性病理学会総会
- Year and Date
  2012-02-03
- Data Source
  KAKENHI-PROJECT-22710061
[Presentation] Molecular cloning of the gene for UV-Sensitive Syndrome with deficiencies in Transcription-coupled DNA repair2011
- Author(s)
  Xue Zhang, Katsuyoshi Horibata, Masafumi Saijo, Chie Ishigami, Akiko Ukai, Shinichiro Kanno, Edward G. Neilan, Hidetoshi Tahara, Masamitsu Honma, Takehiko Nohmi, Akira Yasui and Kiyoji Tanaka
- Organizer
  Conference : Response to DNA damage : from molecular mechanism to human disease
- Place of Presentation
  Egmond aan Zee, Netherlands
- Year and Date
  2011-04-04
- Data Source
  KAKENHI-PROJECT-22710061
[Presentation] Further Development of the Rat Pig-a Mutation assay : Measuring Rat Pig-a Mutant Bone Marrow Erythroids and a High Throughput Assay for Mutant Peripheral Blood Reticulocytes2011
- Author(s)
  Takafumi Kimoto, Satsuki Chikura, Kumiko Suzuki, Xiao mei Kobayashi, Yasuhiro Itano, Katsuyoshi Horibata, Masamitsu Honma, Vasily N. Dobrovolsky, Robert H. Heflich, Daishiro Miura and Yoshinori Kasahara
- Organizer
  Environmental Mutagen Society 42nd Annual Meeting
- Place of Presentation
  Montreal
- Year and Date
  2011-10-17
- Data Source
  KAKENHI-PROJECT-22710061
[Presentation] In Vitro Genotoxicity Tests Using Primary Hepatocytes2011
- Author(s)
  Horibata, K., et.al.
- Organizer
  Environmental Mutagen Society 42nd Annual Meeting
- Place of Presentation
  モントリオール
- Year and Date
  2011-10-17
- Data Source
  KAKENHI-PROJECT-22710061
[Presentation] ラット末梢血を用いるPig-aアッセイ共同研究:測定技術の共有化と施設間差に関する研究報告2011
- Author(s)
  木本崇文,堀端克良,武藤重治,真田尚和,橋本和之,伊東悟,宇野芳文,本間正充
- Organizer
  日本環境変異原学会第40回大会
- Year and Date
  2011-11-21
- Data Source
  KAKENHI-PROJECT-22710061
[Presentation] A Japanese Collaborative Study on Rat Pig-a Assay ; Report on a Transferability of the Assay Method and Interlaboratory Difference2011
- Author(s)
  Takafumi Kimoto, Katsuyoshi Horibata, Shigeharu Muto, Hisakazu Sanada, Kazuyuki Hashimoto, Satoru Itoh, Yoshifumi Uno and Masamitsu Honma
- Organizer
  Environmental Mutagen Society 42nd Annual Meeting
- Place of Presentation
  Montreal
- Year and Date
  2011-10-16
- Data Source
  KAKENHI-PROJECT-22710061
[Presentation] In vitro genotoxicity assay using primary hepatocytes derived from gpt delta transgenic mouse2011
- Author(s)
  堀端克良,増村健一,能美健彦,本間正充
- Organizer
  第70回日本癌学会学術総会
- Year and Date
  2011-10-05
- Data Source
  KAKENHI-PROJECT-22710061
[Presentation] 新規in vivo遺伝子突然変異評価系(Pig-aアッセイ)の検討:骨髄エリスロイド及び末梢血網状赤血球を用いるPig-aアッセイの開発2011
- Author(s)
  木本崇文,千藏さつき,鈴木久美子,小林小梅,板野泰弘, Vasily N. Dobrovolsky, Robert H. Heflich,堀端克良,本間正充,三浦大志郎,笠原義典
- Organizer
  第38回日本トキシコロジー学会学術年会
- Year and Date
  2011-07-11
- Data Source
  KAKENHI-PROJECT-22710061
[Presentation] Molecular cloning of the gene for UV-sensitive syndrome with deficiencies in transcription-coupled DNA repair2011
- Author(s)
  Xue Zhang, Katsuyoshi Horibata, Masafumi Saijo, Chie Ishigami, Akiko Ukai, Shinichiro Kanno, Edward. G Neilan, Hidetoshi Tahara, Masamitsu Honma, Takehiko Nohmi, Akira Yasui and Kiyoji Tanaka
- Organizer
  第34回日本分子生物学会年会
- Year and Date
  2011-12-15
- Data Source
  KAKENHI-PROJECT-22710061
[Presentation] Pig-aアッセイとトランスジェニック突然変異試験の組合せに関する研究2011
- Author(s)
  堀端克良, et.al.
- Organizer
  日本環境変異原学会第40回大会
- Place of Presentation
  東京
- Year and Date
  2011-11-22
- Data Source
  KAKENHI-PROJECT-22710061
[Presentation] Pig-aアッセイとトランスジェニック突然変異試験の組合せに関する研究2011
- Author(s)
  堀端克良,鵜飼明子,木本崇文,鈴木哲矢,鴨下渚,能美健彦,本間正充
- Organizer
  日本環境変異原学会第40回大会
- Year and Date
  2011-11-22
- Data Source
  KAKENHI-PROJECT-22710061
[Presentation] In Vitro Genotoxicity Tests Using Primary Hepatocytes2011
- Author(s)
  Katsuyoshi Horibata, Akiko Ukai, Kenichi Masumura, Takehiko Nohmi and Masamitsu Honma
- Organizer
  Environmental Mutagen Society 42nd Annual Meeting
- Place of Presentation
  Montreal
- Year and Date
  2011-10-17
- Data Source
  KAKENHI-PROJECT-22710061
[Presentation] Evaluation of in vivo genotoxicity of glycidol and 3-MCPD and associated esters, using Pig-A and micronucleus assays2011
- Author(s)
  大波冴子,曹永晩,豊田武士,堀端克良,本間正充,能美健彦,西川秋佳,小川久美子
- Organizer
  第70回日本癌学会学術総会
- Year and Date
  2011-10-05
- Data Source
  KAKENHI-PROJECT-22710061
[Presentation] UVSSA and USP7 cooperate to stabilize CSB in transcription-coupled DNA repair2011
- Author(s)
  Masafumi Saijo, Xue Zhang, Katsuyoshi Horibata, Chie Ishigami, Akiko Ukai, Shin-ichiro Kanno, Hidetoshi Tahara, Edward G. Neilan, Masamitsu Honma, Takehiko Nohmi, Akira Yasui and Kiyoji Tanaka
- Organizer
  第34回日本分子生物学会年会
- Year and Date
  2011-12-15
- Data Source
  KAKENHI-PROJECT-22710061
[Presentation] In vitro genotoxicity assay using primary hepatocytes derived from gpt delta transgenic mouse2011
- Author(s)
  堀端克良, et.al.
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2011-10-05
- Data Source
  KAKENHI-PROJECT-22710061
[Presentation] In vivo gene mutation assay using endogenous Pig-A gene2010
- Author(s)
  Horibata, K., et al.
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
- Place of Presentation
  神戸ポートアイランド(兵庫県)
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-22710061
[Presentation] In viro genotoxicity assay using primary hepatocytes derived from gpt delta transgeinc mouse2010
- Author(s)
  Horibata, K., et al.
- Organizer
  日本環境変異原学会第39回大会
- Place of Presentation
  つくば国際会議場(茨城県)
- Year and Date
  2010-11-16
- Data Source
  KAKENHI-PROJECT-22710061
[Presentation] DNA2本鎖切断修復に対する低線量放射線等の環境ストレスの影響2010
- Author(s)
  本間正充,安井学,堀端克良,鈴木哲矢,谷田貝文夫
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
- Year and Date
  2010-12-07
- Data Source
  KAKENHI-PROJECT-22710061
[Presentation] gpt deltaトランスジェニックマウス由来初代培養肝細胞を用いたin vitro遺伝毒性試験2010
- Author(s)
  堀端克良,鵜飼明子,増村健一,能美健彦,本間正充
- Organizer
  日本環境変異原学会第39回大会
- Year and Date
  2010-11-16
- Data Source
  KAKENHI-PROJECT-22710061
[Presentation] Molecular cloning of the gene for UV-sensitive syndrome with deficiencies in transcription-coupled DNA repair2010
- Author(s)
  Zhang Xue,石上智愛,堀端克良,鵜飼明子,本間正充,能美健彦,田原英俊,田中亀代次
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-22710061
[Presentation] In vivo gene mutation assay using endogenous Pig-A gene2010
- Author(s)
  堀端克良,鵜飼明子,木本崇文,三浦大志郎,本間正充
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-22710061
[Presentation] IN VITRO CHROMOSOME ABERRATION AND CELL TRANSFORMATION TESTS ON FULLEREN AND MALTI-WALL CARBON NANOTUBES2010
- Author(s)
  Masamitsu Honma, Katsuyoshi Horibata, Toshitaka Takahashi, Shin Asada, Takumi Hara, Yuzuki Nakagawa, Atsuko Ikeda, Kohji Yamakage and Akihiko Hirose
- Organizer
  40th Meeting of European Environmental Mutagen Society
- Place of Presentation
  Oslo, Norway
- Year and Date
  2010-09-16
- Data Source
  KAKENHI-PROJECT-22710061
[Presentation] Novel function of nucleotide excision repair factor and its relevance to xeroderma pigmentosum and Cockayne syndrome.2009
- Author(s)
  Kiyoji Tanaka, Shinsuke Ito, Katsuyoshi Horibata, Takashi Narita, Masafumi Saijo
- Organizer
  10th International Conference on Environmental Mutagens
- Place of Presentation
  Florence, Italy
- Data Source
  KAKENHI-PROJECT-17109006
[Presentation] CBS蛋白質の機能とコケイン症候群の発症2008
- Author(s)
  堀端克良
- Organizer
  第67回日本癌学会総会シンポジウム「DNA修復ネットワークの異常と発癌」
- Place of Presentation
  名古屋
- Year and Date
  2008-10-29
- Data Source
  KAKENHI-PROJECT-17109006
[Presentation] Truncated CSB protein causes a defect in repair of DNA topoisomerase I-associated lesions: Implication for Cockayne syndrome.2008
- Author(s)
  Kiyoji Tanaka, Katuyoshi Horibata
- Organizer
  6th 3R Symposium
- Place of Presentation
  Shizuoka, Japan
- Data Source
  KAKENHI-PROJECT-17109006
[Presentation] CSB遺伝子突然変異により発症するヒト遺伝疾患の分子病態2008
- Author(s)
  堀端克良
- Organizer
  第31回日本分子生物学会年会第81回日本生化学会大会合同大会(BMB2008)
- Place of Presentation
  神戸
- Year and Date
  2008-12-11
- Data Source
  KAKENHI-PROJECT-17109006
[Presentation] XPD遺伝子突然変異と臨床症状の分子解析2007
- Author(s)
  堀端克良
- Organizer
  第30回日本分子生物学会年会・第80回日本生化学会大会合同大会
- Place of Presentation
  横浜
- Year and Date
  2007-12-13
- Data Source
  KAKENHI-PROJECT-18890099
[Presentation] Genetic analysis of UV-sensitive syndrome.2007
- Author(s)
  Kiyoji Tanaka, Katsuyoshi Horibata, Chie Ishigami.
- Organizer
  CEE Europian Network Meeting
- Place of Presentation
  Molsheim, France
- Data Source
  KAKENHI-PROJECT-17109006
[Presentation] XPD遺伝子に突然変異を持つCOFS症候群患者の分子解析2007
- Author(s)
  堀端克良
- Organizer
  日本人類遺伝学会第52回大会
- Place of Presentation
  東京
- Year and Date
  2007-09-13
- Data Source
  KAKENHI-PROJECT-18890099
[Presentation] MMS/Pig-a共同研究:アクリルアミドの遺伝毒性評価
- Author(s)
  堀端克良，鵜飼明子，本間正充
- Organizer
  日本環境変異原学会第43回大会
- Place of Presentation
  東京
- Year and Date
  2014-12-04 – 2014-12-05
- Data Source
  KAKENHI-PROJECT-26870867
[Presentation] 共同研究報告 I:Pig-a assay 進捗状況報告
- Author(s)
  堀端克良
- Organizer
  哺乳動物試験研究会第64回定例会
- Place of Presentation
  熱海
- Year and Date
  2014-06-20 – 2014-06-21
- Data Source
  KAKENHI-PROJECT-26870867
[Presentation] マウス、ラットおよびヒト由来のごく微量末梢血を用いて解析可能なPig-a/ PIG-A in vivo突然変異試験法
- Author(s)
  堀端克良，鵜飼明子，石川恵生，菅野絢子，木本崇文，本間正充
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-26870867
[Presentation] Pig-a/PIGRETアッセイに関する短期試験への有用性：MMS共同研究報告
- Author(s)
  山田雅巳, 堀端克良, 鵜飼明子, 木本崇文, 千藏さつき, 伊東悟, 武藤重治, 宇野芳文, 真田尚和, 高島理恵,志賀野美幸,高沢博修, 濵田修一,山本美佳, 堀妃佐子, 堤絵梨, 和田邦生, 前田晃央, 小坂瑞樹, 木村葵, 菊月隆太, 荻原庸介, 京谷恭弘, 足立秀樹, 上松泰明, 吉田唯真, 成見香瑞範, 福田隆之, 鈴木裕太, 後藤玄, 森田健, 本間正充
- Organizer
  日本環境変異原学会第43回大会
- Place of Presentation
  東京
- Year and Date
  2014-12-04 – 2014-12-05
- Data Source
  KAKENHI-PROJECT-26870867
[Presentation] ESTABLISHMENT OF HUMAN PIG-A ASSAY AND APPLICATION TO GENOTOXICITY MONITORING OF CANCER CHEMOTHERAPEUTIC PATIENTS
- Author(s)
  K. Horibata, M. Honma
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-26870867

1. 増村健一 (40291116)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
2. TANAKA Kiyoji (80144450)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
3. SAIJO Masafumi (90221986)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. NARITA Takashi (50437399)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. HONMA Masamitsu (30250179)

# of Collaborated Projects: 1 results

# of Collaborated Products: 22 results
6. 倉岡功 (60335396)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 山田雅巳 (80230481)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. KANNO Shinichirou

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. TOYODA Takeshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 田原栄俊

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 若杉光生

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 松永司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 猪部学

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Horibata Katsuyoshi 堀端 克良

堀端 克良 ホリバタ カツヨシ

HORIBATA Katsuyoshi 堀端 克良

Research Projects

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Co-Researchers

遺伝情報発現と遺伝子突然変異の相関Principal Investigator

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A study on DNA damages in germ cells of male mice and germline mutations induced in the offspring

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Analysis of mutagenesis relating to DNA topology, transcription and DNA repairPrincipal Investigator

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Analysis of DNA topology, transcription and DNA repairPrincipal Investigator

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Comprehensive analyses of DNA Topoisomerase I and relating DNA repairPrincipal Investigator

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コケイン症候群B群で見られる早期老化症状発症システムの解析Principal Investigator

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Molecular genetic analysis of cellular response to transcription-blocking DNA damage and its defective disorders

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[Journal Article] Development of a new quantitative structure?activity relationship model for predicting Ames mutagenicity of food flavor chemicals using StarDrop? auto-Modeller?2021

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[Journal Article] In vivo and in vitro mutagenicity of perillaldehyde and cinnamaldehyde2021

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[Journal Article] In vivo genotoxicity testing strategies: Report from the 7th International Workshop on Genotoxicity Testing (IWGT)2019

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[Journal Article] Standard protocol for the total red blood cell Pig-a assay used in the interlaboratory trial organized by the Mammalian Mutagenicity Study Group of the Japanese Environmental Mutagen Society.2018

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[Journal Article] Measuring Reproducibility of Dose Response Data for the Pig-a Assay using Covariate Benchmark Dose Analysis.2016

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[Journal Article] Evaluation of mutagenicity of acrylamide using RBC Pig-a and PIGRET assays by single peroral dose in rats.2016

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[Journal Article] The in vivo Pig-a assay: A report of the International Workshop On Genotoxicity Testing (IWGT) Workgroup.2015

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Horibata Katsuyoshi 堀端克良

堀端克良ホリバタカツヨシ

HORIBATA Katsuyoshi 堀端克良