MOCHIZUKI Yasushi 望月保志

Researcher Number	40404256
Affiliation (Current)	2022: 長崎大学, 病院(医学系), 准教授
Affiliation (based on the past Project Information) *help	2017 – 2021: 長崎大学, 病院(医学系), 准教授 2014 – 2016: 長崎大学, 病院(医学系), 講師 2013: 長崎大学, 大学病院, 講師
Review Section/Research Field	Principal Investigator Urology / Basic Section 56030:Urology-related Except Principal Investigator Urology / Basic Section 56030:Urology-related
Keywords	Principal Investigator 腎細胞癌 / 肉腫様腎細胞癌 / 予後不良因子 / 標的分子 / 肉腫様腎癌 / 癌関連分子同定 / 機能解明 / 治療標的 / 腫瘍学 / 薬物療法 … More / 治療効果 / 腎臓 / 鉄動態 / 悪性腫瘍 / フェロトーシス / 腎癌 / 新規治療戦略 / 新規治療薬 / 分子機構解明 / 治療戦略 … More Except Principal Investigator 膀胱癌 / 腎細胞癌 / 4N1K-peptide / Thrombospondins / Angiogenesis / TWIST / Hemeoxygenase-1 / Human antigen R / Thrombospondin / 血管新生 / 化学発癌マウスモデル / 泌尿器癌 / 表在性膀胱癌 / HO-1 / 免疫染色 / Fes / 尿路癌 / 癌細胞増殖 / 癌細胞浸潤 / 予後 / TUBB3 / 化学療法 / 細胞増殖 / 細胞浸潤 / 細胞遊走 / 遊走能 / Fer / T24 / 癌免疫 / TNF-α / TGF-β / マクロファージ / ローヤルゼリー / 転移性腎癌 / 治療効果予測因子 / MSCF / 腎癌 / 腫瘍免疫 / 癌微小環境 / 微小環境 / リンパ球 / 細胞培養 / 倫理委員会 / データベース / 尿管 / インドシアニングリーン / ラベリング / リンパ管 / スフェロイド / ３Dバイオプリンティング / 蠕動運動 / 再生医療 / バイオ３Dプリンター / 腸管 Less

スキャフォールドフリーの3次元構造体による機能を有する人工尿管の作成
- Principal Investigator
  
  高木克典
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Nagasaki University
Elucidation of molecular mechanism of ferroptosis and construction of new therapeutic strategy in renal cell carcinomaPrincipal Investigator
- Principal Investigator
  
  MOCHIZUKI Yasushi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Nagasaki University
analysis of the effect of changes in the microenvironment around cancer on renal cancer stem cells: development of new treatment strategies
- Principal Investigator
  
  Ohba Kojiro
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Nagasaki University
Investigation on usefulness of Fes / Fer as new therapeutic target and predictive factor in urothelial cancer
- Principal Investigator
  
  TAKEHARA Kosuke
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Nagasaki University
Evaluation of usefulness of sarcomatoid renal cell carcinoma experiment model using clinical specimen data and search for new therapeutic targets.Principal Investigator
- Principal Investigator
  
  MOCHIZUKI Yasushi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Nagasaki University
Analysis of the pathological role of HO-1 in kidney cancer cells and cancer interstitial tissue and construction of new therapeutic strategies
- Principal Investigator
  
  MATSUO Tomohiro
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Nagasaki University
Investigation on clinicopathological signficance and tumor suppressive effects of 4N1K-peptide in bladder cancer
- Principal Investigator
  
  MIYATA Yasuyoshi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Nagasaki University

All 2021 2020 2019 2018 2017 2015

All Journal Article Presentation

[Journal Article] Effect of oral intake of royal jelly on endothelium function in hemodialysis patients: study protocol for multicenter, double-blind, randomized control trial2021
- Author(s)
  Kojiro Ohba , Yasuyoshi Miyata , Takeaki Shinzato , Satoshi Funakoshi , Kanenori Maeda , Tomohiro Matsuo , Kensuke Mitsunari , Yasushi Mochizuki , Tomoya Nishino , Hideki Sakai
- Journal Title
  
  Trials
  
  Volume: 22 Pages: 950-950
- DOI
  10.1186/s13063-021-05926-x
- NAID
  120007190859
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09731
[Journal Article] Oral intake of royal jelly improves anti?cancer effects and suppresses adverse events of molecular targeted therapy by regulating TNF?α and TGF?β in renal cell carcinoma: A preliminary study based on a randomized double?blind clinical trial2020
- Author(s)
  Miyata Yasuyoshi、Araki Kyohei、Ohba Kojiro、Mastuo Tomhiro、Nakamura Yuichiro、Yuno Tsutomu、Mukai Yuta、Otsubo Asato、Mitsunari Kensuke、Mochizuki Yasushi、Sakai Hideki
- Journal Title
  
  Molecular and Clinical Oncology
  
  Volume: 13 Pages: 29-29
- DOI
  10.3892/mco.2020.2099
- Data Source
  KAKENHI-PROJECT-18K09170
[Journal Article] Oral Intake of Royal Jelly Has Protective Effects Against Tyrosine Kinase Inhibitor-Induced Toxicity in Patients with Renal Cell Carcinoma: A Randomized, Double-Blinded, Placebo-Controlled Trial.2018
- Author(s)
  Araki K, Miyata Y, Ohba K, Nakamura Y, Matsuo T, Mochizuki Y, Sakai H.
- Journal Title
  
  Medicines
  
  Volume: 6 Pages: 1-11
- DOI
  10.3390/medicines6010002
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09170
[Journal Article] Smoking-induced changes in cancer-related factors in patients with upper tract urothelial cancer.2015
- Author(s)
  Miyata Y, Mitsunari K, Akihiro A, Watanabe SI, Mochizuki Y, Sakai H.
- Journal Title
  
  Molucular and Clinical Oncology
  
  Volume: 3 Pages: 287-294
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25462487
[Presentation] 透析療法とOncoNephrology, 透析腎癌の薬物療法, オンコネフロロジストの視点で再考する2021
- Author(s)
  望月保志, 大庭康司郎, 宮田康好, 酒井英樹
- Organizer
  日本透析医学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-19K09731
[Presentation] YAP expression plays important roles in malignant aggressiveness by regulating the infiltration of CD57+ natural killer cells, CD68+ macrophages, and mast cells and the expression of VEGF-A and PD-L1 in clear cell renal cell carcinoma.2021
- Author(s)
  Ohba K., Miyata Y., Harada J., Matsuda T., Kondo T., Otsubo A., Mukae Y., Ito H., Kurata H., Mitsunari K., Matsuo T., Mochizuki Y., Sakai H.
- Organizer
  The 116th American Urological Association
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09170
[Presentation] 当科におけるaxitinibの治療成績2019
- Author(s)
  迎祐太, 大庭康司郎, 上田康史, 中村裕一郎, 相良祐次, 松尾朋博, 望月保志, 宮田康好, 酒井英樹
- Organizer
  第107回日本泌尿器科学会総会
- Data Source
  KAKENHI-PROJECT-18K09170
[Presentation] Case study of inferior vena caval tumor thrombus in patients with renal cell carcinoma2019
- Author(s)
  Kojiro Ohba, Hiroki Kurata, Yuta Mukae, Yuichiro Nakamura, Hiromi Nakanishi, Yuji Sagara, Tomohiro Matsuo, Yasushi Mochizuki, Yasuyoshi Miyata, Hideki Sakai
- Organizer
  第50回腎癌研究会
- Data Source
  KAKENHI-PROJECT-18K09170
[Presentation] Initial experience of nivolumab treatment for patients with metastatic renal cell carcinoma.2018
- Author(s)
  Kojiro Ohba, Hidenori Ito, Yuta Mukae, Yuichiro Nakamura, Hiromi Nakanishi, Yuji Sagara, Tomohiro Matsuo, Yasushi Mochizuki, Yasuyoshi Miyata, Hideki Sakai
- Organizer
  第56回日本癌治療学会学術総会
- Data Source
  KAKENHI-PROJECT-18K09170
[Presentation] Intake of royal jelly prevents sunitinib-induced appetite loss in patients with renal cell carcinoma: Correlation with serum levels of transforming growth factor-β and macrophage colony-stimulating factor.2018
- Author(s)
  Kojiro Ohba, Yasuyoshi Miyata, Yuichiro Nakamura, Kyohei Araki, Takuji Yasuda, Yuji Sagara, Tomohiro Matuso, Yasushi Mochizuki, Hideki Sakai
- Organizer
  113th AUA annual meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09170
[Presentation] 初期治療として腎摘除を施行しなかった腎細胞癌症例の臨床的検討2018
- Author(s)
  大庭　康司郎、原田　淳樹、荒木　杏平、中西　裕美、相良　祐次、松尾　朋博、望月　保志、宮田　康好、酒井　英樹
- Organizer
  第106回日本泌尿器科学会総会
- Data Source
  KAKENHI-PROJECT-18K09170
[Presentation] Nivolumabによるimmuno-related adverse events（irAE）の経験2018
- Author(s)
  大庭　康司郎、松田　剛、中西　裕美、安田　拓司、相良　祐次、松尾　朋博、望月　保志、宮田　康好、酒井　英樹
- Organizer
  第49回腎癌研究会
- Data Source
  KAKENHI-PROJECT-18K09170
[Presentation] Pathological and prognostic significance of densities ofCD57+ (natural killer cells),CD68+ (macrophage), andmastcells in renal cell carcinoma tissues2017
- Author(s)
  Yasushi Mochizuki
- Organizer
  European Association of Urology 2017
- Place of Presentation
  ロンドン（英国）
- Year and Date
  2017-03-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10595
[Presentation] Pathological and prognostic significance of densities of CD57+ (natural killer cells), CD68+ (macrophage), and mast cells in renal cell carcinoma tissues2017
- Author(s)
  Yasushi Mochizuki
- Organizer
  The Congress of European association of Urology 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10595

1. MIYATA Yasuyoshi (60380888)

# of Collaborated Projects: 6 results

# of Collaborated Products: 12 results
2. TAKEHARA Kosuke (40580345)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. Ohba Kojiro (20593825)

# of Collaborated Projects: 2 results

# of Collaborated Products: 11 results
4. SAKAI Hideki (40235122)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. MATSUO Tomohiro (60622024)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 高木克典 (90635856)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 中山功一 (50420609)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 江口正倫 (70585405)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 永安武 (80284686)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 松本桂太郎 (80404268)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 町野隆介 (90728081)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 谷口大輔 (20773758)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 山根裕介 (90457549)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. NAKANISHI Hiromi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. NAKAMURA Yuichiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. ARAKI Kyohei

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

MOCHIZUKI Yasushi 望月 保志

Research Projects

Research Products

Co-Researchers

スキャフォールドフリーの3次元構造体による機能を有する人工尿管の作成

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of molecular mechanism of ferroptosis and construction of new therapeutic strategy in renal cell carcinomaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

analysis of the effect of changes in the microenvironment around cancer on renal cancer stem cells: development of new treatment strategies

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Investigation on usefulness of Fes / Fer as new therapeutic target and predictive factor in urothelial cancer

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Evaluation of usefulness of sarcomatoid renal cell carcinoma experiment model using clinical specimen data and search for new therapeutic targets.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of the pathological role of HO-1 in kidney cancer cells and cancer interstitial tissue and construction of new therapeutic strategies

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Investigation on clinicopathological signficance and tumor suppressive effects of 4N1K-peptide in bladder cancer

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Effect of oral intake of royal jelly on endothelium function in hemodialysis patients: study protocol for multicenter, double-blind, randomized control trial2021

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Oral intake of royal jelly improves anti?cancer effects and suppresses adverse events of molecular targeted therapy by regulating TNF?&alpha; and TGF?&beta; in renal cell carcinoma: A preliminary study based on a randomized double?blind clinical trial2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Oral Intake of Royal Jelly Has Protective Effects Against Tyrosine Kinase Inhibitor-Induced Toxicity in Patients with Renal Cell Carcinoma: A Randomized, Double-Blinded, Placebo-Controlled Trial.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Smoking-induced changes in cancer-related factors in patients with upper tract urothelial cancer.2015

Author(s)

Journal Title

Data Source

[Presentation] 透析療法とOncoNephrology, 透析腎癌の薬物療法, オンコネフロロジストの視点で再考する2021

Author(s)

Organizer

Data Source

[Presentation] YAP expression plays important roles in malignant aggressiveness by regulating the infiltration of CD57+ natural killer cells, CD68+ macrophages, and mast cells and the expression of VEGF-A and PD-L1 in clear cell renal cell carcinoma.2021

Author(s)

Organizer

Data Source

[Presentation] 当科におけるaxitinibの治療成績2019

Author(s)

Organizer

Data Source

[Presentation] Case study of inferior vena caval tumor thrombus in patients with renal cell carcinoma2019

Author(s)

MOCHIZUKI Yasushi 望月保志

[Journal Article] Oral intake of royal jelly improves anti?cancer effects and suppresses adverse events of molecular targeted therapy by regulating TNF?α and TGF?β in renal cell carcinoma: A preliminary study based on a randomized double?blind clinical trial2020