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HIRATA Takao  平田 孝夫

ORCIDConnect your ORCID iD *help
Researcher Number 40420533
Affiliation *help 2007 – 2009 : Yamaguchi University, 医学部・附属病院, 助教
2007 – 2009 : Yamaguchi Univ., Hospital, Assistant Professor
2008 : 山口大学, 医学部附属病院, 助手
2006 : 山口大学, 医学部附属病院, 助手
Review Section/Research Field
Principal Investigator
Anesthesiology/Resuscitation studies
Except Principal Investigator
Anesthesiology/Resuscitation studies
Keywords
Principal Investigator
好中球エラスターゼ / 海馬CA1 / カスパーゼ / 虚血性神経細胞死 / 蘇生学 / アポトーシス / 細胞外マトリックス / シベレスッタトNa / 虚血 / 一過性前脳虚血 … More / 海馬CAl / PAR-2受容体 / 脳保護 / 中枢神経 … More
Except Principal Investigator
高気圧酸素 / 前脳虚血 / 脳虚血耐性 / p38 MAP kinase / 炎症反応 / 脳虚血 / 術後高次脳機能障害 / クロストレランス / p38 MAPK / 脂肪塞栓 / Lipopolysaccharide / 耐性誘導 / neurotrophin / 中枢神経 / 神経栄養因子 / 耐性関連因子 / 脳梗塞 / immuno / forebrain ischemia / 虚血性神経細胞死 / ischemic tolerance / 虚血 / 遺伝子 / LPS / 虚血耐性 / 脳浮腫 / p38 / 脂肪塞 / 全身炎症反応 / hyperbric oxygen / inflammatory response / 海馬CA1 / 免疫・炎症 Less
  • Research Projects

    (5results)
  • Research Products

    (15results)
  • Co-Researchers

    (7People)
  •  高気圧酸素による虚血耐性誘導を応用した脳血管障害の新規予防・治療戦略の開発

    • Principal Investigator
      坂部 武史
    • Project Period (FY)
      2008
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      Yamaguchi University
  •  The role of neutrophil elastase in the development of neuronal damage following transient forebrain ischemia.Principal Investigator

    • Principal Investigator
      HIRATA Takao
    • Project Period (FY)
      2008 – 2009
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      Yamaguchi University
  •  The effect of systemic inflammation to ischemic brain damage and hypothermic protection

    • Principal Investigator
      ISHIDA Kazuyoshi
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      Yamaguchi University
  •  虚血性中枢神経障害の病態解明と好中球エラスターゼ阻害薬の効果に関する検討Principal Investigator

    • Principal Investigator
      平田 孝夫
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      Yamaguchi University
  •  Mechanism for ischemic crosstoleance in central nervous system and its therapeutic application

    • Principal Investigator
      SAKABE Takefumi
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      Yamaguchi University

All 2009 2007 2006 2005

All Journal Article Presentation

  • [Journal Article] Neutrophil elastase inhibitor attenuates hippocampal neuronal damage after transient forebrain ischemia in rats.2009

    • Author(s)
      Matayoshi H., Hirata T., Yamashita S., Ishida K., Mizukami Y., Gondo T., Matsumoto M., Sakabe T.
    • Journal Title

      Brain Res. 1259

      Pages : 98-106

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20791076
  • [Journal Article] The temporal profile of genomic responses and protein synthesis in isohemic tolerance of the rat brain induced by repeated hyperbaric oxygen.2007

    • Author(s)
      Takao Hirata
    • Journal Title

      Brain Research 1130

      Pages : 214-222

    • Data Source
      KAKENHI-PROJECT-17390429
  • [Journal Article] The temporal profile of genomic responses and protein synthesis in ischemic tolerance of the rat brain induced by repeated hyperbaric oxygen2007

    • Author(s)
      Takao, Hirata, Ying, Jun, Cue, Takeshi, Funakoshi, Yoichi, Mizukami,Yu-ichiro, Ishikawa, Futoshi, Shibasaki, Mishiya, Matsumoto, Takefumi, Sakabe
    • Journal Title

      Brain Research 1130(1)

      Pages : 214-222

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390429
  • [Journal Article] The temporal profile of genomic responses and protein synthesis in ischemic tolerance of the rat brain induced by repeated hyperbaric oxygen.2007

    • Author(s)
      Takao Hirata
    • Journal Title

      Brain Research 1130

      Pages : 214-222

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17390429
  • [Journal Article] Ischemic preconditioning in the central nervous system2005

    • Author(s)
      Mishiya, Matsumoto, Kazuhiko, Nakakimura, Mitsuyoshi, Yoshida, Takao, Hirata, Takefumi, Sakabe
    • Journal Title

      Japanese Journal of Reanimatology 24

      Pages : 76-81

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390429
  • [Presentation] 好中球エラスタ-ゼ阻害薬ONO-5046はラット-過性脳虚血後の海馬CA1神経細胞死を軽減させる2009

    • Author(s)
      平田孝夫
    • Organizer
      日本麻酔科学会 第56会学術集会
    • Place of Presentation
      神戸
    • Year and Date
      2009-08-16
    • Data Source
      KAKENHI-PROJECT-20791076
  • [Presentation] 好中球エラスターゼ阻害薬ONO-5046はラット一過性脳虚血後の海馬CA1神経細胞死を軽減させる2009

    • Author(s)
      平田孝夫, 又吉宏昭, 山下敦夫, 福田志朗, 石田和慶, 松本美志也, 坂部武史
    • Organizer
      日本麻酔科学会第56回学術集会
    • Place of Presentation
      神戸
    • Year and Date
      2009-08-16
    • Data Source
      KAKENHI-PROJECT-20791076
  • [Presentation] Ischemic tolerance induced by repeated hyperbaric oxygen in ratbrain: Time window and genome-wide gene and protein expression2007

    • Author(s)
      Takao Hirata
    • Organizer
      The 23^<rd> International Symposium on Cerebral Blood Flow, Metabolism and Function. The 8^<th> International Conference on Quantification of Brain Function with PET.
    • Place of Presentation
      Osaka
    • Year and Date
      2007-05-21
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390429
  • [Presentation] Ischemic tolerance induced by repeated hyperbaric oxygen In rat brain:Time window and genome-wide gene and protein expression2007

    • Author(s)
      Takao Hirata, et. al.
    • Organizer
      Brain'07 & Brain PET'07
    • Place of Presentation
      Osaka
    • Year and Date
      2007-05-21
    • Data Source
      KAKENHI-PROJECT-17390429
  • [Presentation] Ischemic tolerance induced by repeated hyperbaric oxygen in rat brain : Time window and genome-wide gene and protein expression2007

    • Author(s)
      Takao, Hirata, Ying, Jun Cui, Takeshi, Funakoshi, Yoichi, Mizukami, Yu-ichiro, Ishikawa, Futoshi, Shibasaki, Mishiya, Matsumoto, Takefumi, Sakabe
    • Organizer
      The 8th International Conference on Quantification of Brain Function with PET
    • Place of Presentation
      Osaka, Japan
    • Year and Date
      2007-05-21
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390429
  • [Presentation] Ischemic tolerance induced by repeated hyperbaric oxygen in rat brain : Time window and genome-wide gene and protein expression2007

    • Author(s)
      Takao, Hirata, Ying, Jun, Cui, Takeshi, Funakoshi, Yoichi, Mizukami, Yu-ichiro, Ishikawa, Futoshi, Shibasaki, Mishiya, Matsumoto, Takefumi, Sakabe
    • Organizer
      The 23rd International Symposium on Cerebral Blood Flow, Metabolism and Function
    • Place of Presentation
      Osaka, Japan
    • Year and Date
      2007-05-21
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390429
  • [Presentation] 高気圧酸素による脳虚血耐性と遺伝子変化2006

    • Author(s)
      平田 孝夫
    • Organizer
      日本麻酔科学会第53回学術集会
    • Place of Presentation
      神戸
    • Year and Date
      2006-06-01
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390429
  • [Presentation] Ischemic tolerance and genomic responses induced by hyperbaric oxygen2006

    • Author(s)
      Takao, Hirata, Ying, Jun, Cui, Mishiya, Matsumoto, Takefumi, Sakabe
    • Organizer
      The 53rd Annual Meeting of Japanese Society of Anesthesiologists
    • Place of Presentation
      Kobe, Japan
    • Year and Date
      2006-06-01
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390429
  • [Presentation] Ischemic tolerance induced by repeated hyperbaric oxygen in rat brain2006

    • Author(s)
      Hirata, T, Cui, YJ, Funakoshi, T, Mizukami, Y, Ishikawa, Y, Shibasaki, F, Matsumoto, M, Sakabe, T
    • Organizer
      The 2nd Japan-China-Kores Joint Symposium for Neuroanesthesia
    • Place of Presentation
      Osaka
    • Year and Date
      2006-04-15
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390429
  • [Presentation] Ischemic tolerance induced by repeated hyperbaric oxygen in rat brain2006

    • Author(s)
      Takao Hirata
    • Organizer
      The 2^<nd> Japan-China-Kores Joint Symposium for Neuroanesthesia
    • Place of Presentation
      Osaka
    • Year and Date
      2006-04-15
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390429
  • 1.  SAKABE Takefumi (40035225)
    # of Collaborated Projects : 3results
    # of Collaborated Products : 6results
  • 2.  MATSUMOTO Mishiya (60243664)
    # of Collaborated Projects : 2results
    # of Collaborated Products : 6results
  • 3.  MIZUKAMI Youichi (80274158)
    # of Collaborated Projects : 2results
    # of Collaborated Products : 4results
  • 4.  ISHIDA Kazuyoshi (80314813)
    # of Collaborated Projects : 1results
    # of Collaborated Products : 0results
  • 5.  IIDA Yasuhiko (90304485)
    # of Collaborated Projects : 1results
    # of Collaborated Products : 0results
  • 6.  森本 康裕 (60325230)
    # of Collaborated Projects : 1results
    # of Collaborated Products : 0results
  • 7.  福田 志朗 (70322245)
    # of Collaborated Projects : 1results
    # of Collaborated Products : 0results

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