Toyooka Tatsushi 豊岡達士

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TOYOOKA Tatsushi 豊岡達士

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Researcher Number	40423842
Other IDs
Affiliation (Current)	2025: 独立行政法人労働者健康安全機構労働安全衛生総合研究所, 有害性試験研究領域開発グループ, 部長代理
Affiliation (based on the past Project Information) *help	2016: 独立行政法人労働者健康安全機構労働安全衛生総合研究所, 産業毒性・生体影響研究グループ, 任期付研究員 2015: 独立行政法人労働安全衛生総合研究所, その他部局等, 研究員 2014: 静岡県立大学, 付置研究所, 助教 2006 – 2014: 静岡県立大学, 環境科学研究所, 助教
Review Section/Research Field	Principal Investigator Risk sciences of radiation and chemicals / Risk sciences of radiation/Chemicals Except Principal Investigator Risk sciences of radiation/Chemicals
Keywords	Principal Investigator 紫外線 / ナノマテリアル / フローサイトメーター / 取り込み量 / ナノ粒子 / ナノ毒性 / 遺伝毒性 / DNA修復 / DNA損傷 / クロマチン構造 … More / ヒストン修飾 / 皮膚発癌 / 皮膚癌 / 重金属 / DNA 損傷 / 影響評価 / 環境汚染物質 … More Except Principal Investigator 紫外線 / エピジェネティクス / リン酸化 / ヒストン / DNA損傷 / アセチル化 / ヒストンH3 / 複合影響 / エストロゲン / 化学物質 / 複合暴露 / クロマチン / 修復 / 発がん / 複合曝露 / ヒストンH2AX / 光 / ヒストンH2X Less

Development of new method for risk assessment of nanomaterials by concurrent analysis of uptake potential and toxicity using flowcytometerPrincipal Investigator
- Principal Investigator
  
  Toyooka Tatsushi
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Risk sciences of radiation and chemicals
- Research Institution
  National Institute of Occupational Safety and Health,Japan
ヒストン修飾変化の観点より迫る農薬による紫外線発がん増強の可能性Principal Investigator
- Principal Investigator
  
  豊岡達士
- Project Period (FY)
  2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Risk sciences of radiation and chemicals
- Research Institution
  University of Shizuoka
Relationship between coexposure to chemicals and UV, and recent increase of skin cancer - from a view point of histone modifications
- Principal Investigator
  
  IBUKI Yuko
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  University of Shizuoka
Augmentation of UV-induced carcinogenesis by heavy metals-relationships with histone modification and repair of DNA damagePrincipal Investigator
- Principal Investigator
  
  TOYOOKA Tatsushi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  University of Shizuoka
Effect of combined exposures to multiple chemicals and ultraviolet rays on recent increase of skin cancer-from a view point of histone modifications
- Principal Investigator
  
  IBUKI Yuko
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  University of Shizuoka
Multiple effects of environmental pollutants and ultraviolet light on the recent increase of skin cancer -relationship with histone modification
- Principal Investigator
  
  IBUKI Yuko
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  University of Shizuoka
生体内分子に着目した高感度環境影響評価法の構築Principal Investigator
- Principal Investigator
  
  豊岡達士
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  University of Shizuoka

All 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 Other

All Journal Article Presentation Patent

[Journal Article] Silver nanoparticle-induced phosphorylation of histone H3 at serine 10 is due to dynamic changes in actin filaments and the activation of Aurora kinases.2017
- Author(s)
  Zhao X, Toyooka T, Ibuki Y.
- Journal Title
  
  Toxicology Letters
  
  Volume: S0378-4274(17)30186-8 Pages: 39-47
- DOI
  10.1016/j.toxlet.2017.05.009
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H06893, KAKENHI-PROJECT-15H02828
[Journal Article] 1,2-Dichloropropane generates phosphorylated histone H2AX via cytochrome P450 2E1-mediated metabolism.2017
- Author(s)
  Toyooka T, Yanagiba Y, Suda M, Ibuki Y, Wang RS.
- Journal Title
  
  Toxicology Letters
  
  Volume: 272 Pages: 60-67
- DOI
  10.1016/j.toxlet.2017.03.009
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H06893, KAKENHI-PROJECT-26460817
[Journal Article] Effect of physicochemical character differences on the genotoxic potency of kaolin.2017
- Author(s)
  Kato T, Toyooka T, Ibuki Y, Masuda S, Watanabe M, Totsuka Y.
- Journal Title
  
  Genes & Environment
  
  Volume: 1;39:12 Issue: 1
- DOI
  10.1186/s41021-017-0075-y
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H06893
[Journal Article] Evaluation of chemical phototoxicity, focusing on phosphorylated histone H2AX2015
- Author(s)
  Y. Ibuki and T. Toyooka
- Journal Title
  
  Journal of Radiation Research
  
  Volume: 56 Issue: 2 Pages: 220-228
- DOI
  10.1093/jrr/rru105
- NAID
  40020050279
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24510084
[Journal Article] γ-H2AX induced by linear alkylbenzene sulfonates is due to deoxyribonuclease-1 translocation to the nucleus via actin disruption.2015
- Author(s)
  X. Zhao, T. Toyooka, T. Kubota, G. Yang, Y. Ibuki
- Journal Title
  
  Mutation Research-Fundamental and Molecular Mechanisms of Mutagenesis
  
  Volume: 777 Pages: 33-42
- DOI
  10.1016/j.mrfmmm.2015.04.006
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24510084, KAKENHI-PROJECT-15K12214
[Journal Article] Cigarette sidestream smoke induces histone H3 phosphorylation via JNK and PI3K/Akt pathways, leading to the expression of proto-oncogenes.2014
- Author(s)
  Y.Ibuki, T. Toyooka, X. Zhao and I. Yoshida
- Journal Title
  
  Carcinogenesis
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24510084
[Journal Article] ヒストンH2AXのリン酸化に着目した光毒性評価2014
- Author(s)
  豊岡達士、伊吹裕子
- Journal Title
  
  放射線生物研究
  
  Volume: -
- NAID
  40020050279
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24510084
[Journal Article] Phosphorylation of Histone H2AX Generated by Linear Alkylbenzene Sulfonates and its Suppression by UVB Exposure.2014
- Author(s)
  Kubota T, Toyooka T, Zhao X, Ibuki Y.
- Journal Title
  
  Photochem Photobiol.
  
  Volume: in press Issue: 4 Pages: 845-852
- DOI
  10.1111/php.12268
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25340048
[Journal Article] Phosphorylation of histone H2AX generated by linear alkylbenzene sulfonates and its suppression by UVB exposure.2014
- Author(s)
  T. Kubota, T. Toyooka, X. Zhao and Y. Ibuki
- Journal Title
  
  Photochemistry and Photobiology
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24510084
[Journal Article] Silver ions enhance UVB-induced phosphorylation of histone H2AX.2014
- Author(s)
  X. Zhao, T. Toyooka, Y. Ibuki
- Journal Title
  
  Environmental Molecular Mutagenesis
  
  Volume: 55 Issue: 7 Pages: 556-565
- DOI
  10.1002/em.21875
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24510084
[Journal Article] Phosphorylation of histone H2AX is a useful marker for detecting chemical phototoxicity.2013
- Author(s)
  T. Toyooka　and Y. Ibuki
- Journal Title
  
  Photomedicine and Photobiology
  
  Volume: 35 Pages: 15-16
- Data Source
  KAKENHI-PROJECT-24510084
[Journal Article] Synergistic bactericidal effect by combined exposure to Ag nanoparticles and UVA.2013
- Author(s)
  Zhao X
- Journal Title
  
  Science of the Total Environment
  
  Volume: 458-460 Pages: 54-62
- DOI
  10.1016/j.scitotenv.2013.03.098
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22710065, KAKENHI-PROJECT-24510084
[Journal Article] Nonylphenol polyethoxylates degraded by three different wavelengths of UV and their genotoxic change-detected by generation of γ-H2AX.2013
- Author(s)
  T.Kubota, T. Toyooka and Y. Ibuki
- Journal Title
  
  Photochemistry and Photobiology
  
  Volume: 89 Issue: 2 Pages: 461-467
- DOI
  10.1111/php.12002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24510084, KAKENHI-PROJECT-25340048
[Journal Article] 17-β-estradiol-mediated hyperacetylation of histone H3 and change of repair ability of DNA damage.2013
- Author(s)
  T. Toyooka　and Y. Ibuki
- Journal Title
  
  Photomedicine and Photobiology
  
  Volume: 35 Pages: 21-22
- Data Source
  KAKENHI-PROJECT-24510084
[Journal Article] UVB irradiation changes genotoxic potential of nonylphenolpolyethoxylates-remarkable generation of γ-H2AX with degradation of chemical structure.2013
- Author(s)
  Toyooka T, Kubota T, Ibuki Y.
- Journal Title
  
  Mutagenesis.
  
  Volume: 28 Issue: 1 Pages: 7-14
- DOI
  10.1093/mutage/ges043
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22710065, KAKENHI-PROJECT-24510084, KAKENHI-PROJECT-25340048
[Journal Article] Flow cytometric evaluation of nanoparticles using side-scattered light and reactive oxygen species-mediated fluorescence-correlation with genotoxicity.2012
- Author(s)
  Toduka Y, Toyooka T, Ibuki Y.
- Journal Title
  
  Environ. Sci. Technol.
  
  Volume: 46 Issue: 14 Pages: 7629-36
- DOI
  10.1021/es300433x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22710065
[Journal Article] Nanoparticle uptake measured by flow cytometry2012
- Author(s)
  Ibuki Y, Toyooka T.
- Journal Title
  
  Methods Mol.Biol.
  
  Volume: 926 Pages: 157-66
- DOI
  10.1007/978-1-62703-002-1_11
- ISBN
  9781627030014, 9781627030021
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22710065
[Journal Article] Dual effects of N-acetyl-L-cysteine dependent on NQO1 activity: suppressive or promotive of 9,10-phenanthrenequinone-induced toxicity.2012
- Author(s)
  Toyooka T, Shinmen T, Aarts JM, Ibuki Y.
- Journal Title
  
  Toxicol. Appl. Pharmacol.
  
  Volume: 264 Issue: 3 Pages: 404-12
- DOI
  10.1016/j.taap.2012.08.017
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22710065
[Journal Article] Titanium dioxide particles phosphorylate histone H2AX independent of ROS production2012
- Author(s)
  T. Toyooka, T. Amano, Y. Ibuki
- Journal Title
  
  Mutat Res
  
  Volume: 742(1-2) Issue: 1-2 Pages: 84-91
- DOI
  10.1016/j.mrgentox.2011.12.015
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21510071, KAKENHI-PROJECT-22710065, KAKENHI-PROJECT-24510084
[Journal Article] Nonylphenol polyethoxylates induce phosphorylation of histone H2AX2012
- Author(s)
  T. Toyooka, T. Kubota, Y. Ibuki
- Journal Title
  
  Mutat Res
  
  Volume: 741(1-2) Issue: 1-2 Pages: 57-64
- DOI
  10.1016/j.mrgentox.2011.10.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21510071, KAKENHI-PROJECT-22710065, KAKENHI-PROJECT-24510084
[Journal Article] Phosphorylation of Histone H2AX Is a Powerful Tool for Detecting Chemical Photogenotoxicity.2011
- Author(s)
  Toyooka Tatsushi
- Journal Title
  
  J.Invest.Dermatol.
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22710065
[Journal Article] Phosphorylation of histone H2AX is a powerful tool for detecting chemical photogenotoxicity2011
- Author(s)
  T. Toyooka, M. Ishihama, Y. Ibuki
- Journal Title
  
  J Invest Dermatol
  
  Volume: 131(6) Issue: 6 Pages: 1313-21
- DOI
  10.1038/jid.2011.28
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21510071, KAKENHI-PROJECT-22710065
[Journal Article] UVB in solar-simulated light causes formation of BaP-photoproducts capable of generating phosphorylated histone H2AX2010
- Author(s)
  G. Ohnuki, T. Toyooka, Y. Ibuki
- Journal Title
  
  Mutat. Res
  
  Volume: 702 Pages: 70-70
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21510071
[Journal Article] UVB in solar-simulated light causes formation of BaP-photoproducts capable of generating phosphorylated histone H2AX.2010
- Author(s)
  G.Ohnuki, T.Toyooka, Y.Ibuki
- Journal Title
  
  Mutat.Res.
  
  Volume: 702 Pages: 70-77
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21510071
[Journal Article] Benzo[a]pyrene exposed to solar-simulated light inhibits apoptosis and augments carcinogenicity2010
- Author(s)
  M.Teranishi, T.Toyooka, T.Ohura, S.Masuda, Y.Ibuki
- Journal Title
  
  Chem.Biol.Interact. 185
  
  Pages: 4-11
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21510071
[Journal Article] Dynamics of Ku80 in Living Hamster Cells with DNA Double-Strand Breaks Induced by Chemotherapeutic Drugs.2010
- Author(s)
  M.Koike, A.Koike, J.Sugasawa, T.Toyooka, Y.Ibuki
- Journal Title
  
  J.Vet.Med.Sci.
  
  Volume: 72 Pages: 1405-1412
- NAID
  130000264186
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21510071
[Journal Article] PI3-kinase/ Akt pathway mediates expression of p53 after UVB irradiation.2010
- Author(s)
  Y.Ibuki, M.Akaike, T.Toyooka
- Journal Title
  
  Genes Environ.
  
  Volume: 32 Pages: 85-91
- NAID
  10026961748
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21510071
[Journal Article] Histone deacetylase inhibitor sodium butyrate enhances the cell killing effect of psoralen plus UVA by attenuating nucleotide excision repair2009
- Author(s)
  T. Toyooka, and Y. Ibuki
- Journal Title
  
  Cancer Res 69
  
  Pages: 3492-3500
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19510071
[Journal Article] Histone deacetylase inhibitor sodium butyrate enhances the cell killingeffect of psoralen plus UVA by attenuating nucleotide excision repair.2009
- Author(s)
  T. Toyooka, Y. Ibuki
- Journal Title
  
  Cancer Res. 69
  
  Pages: 3492-3500
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19510071
[Journal Article] Cigarette sidestream smoke induces phosphorylated histone H2AX2009
- Author(s)
  T.Toyooka, Y.Ibuki
- Journal Title
  
  Mutat.Res. 676
  
  Pages: 34-40
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21510071
[Journal Article] Cigarette sidestream smoke induces phosphorylated histone H2AX2009
- Author(s)
  T. Toyooka and Y. Ibuki
- Journal Title
  
  Mutat. Res
  
  Volume: 676 Pages: 34-40
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21510071
[Journal Article] Generation of phosphorylated histone H2AX by benzene metabolites.2008
- Author(s)
  M. Ishihama, T. Toyooka, Y. Ibuki
- Journal Title
  
  Toxicol. In Vitro 22
  
  Pages: 1861-1868
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19510071
[Journal Article] Akt-mediated intracellular oxidation after UVB irradiation suppresses apoptotic cell death induced by cell detachment and serum starvation.2008
- Author(s)
  Y. Ibuki, M. Akaike, T. Toyooka and R. Goto
- Journal Title
  
  Photochem. Photobiol. 84(1)
  
  Pages: 154-61
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19510071
[Journal Article] Akt-mediated intracellular oxidation after UVB irradiation suppresses apoptotic cell death induced by cell detachment and serum starvation2008
- Author(s)
  Y. Ibuki, M. Akaike, T.Toyooka and R.Goto
- Journal Title
  
  Photochem. Photobiol 84(1)
  
  Pages: 154-61
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19510071
[Journal Article] Solar-simulated light-exposed benzo[a]pyrene induces phosphorylation of histone H2AX.2008
- Author(s)
  T. Toyooka, G. Ohnuki and Y. Ibuki
- Journal Title
  
  Mutat. Res 650(2)
  
  Pages: 132-139
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19510071
[Journal Article] Solar-simulated light-exposed benzo[a]pyrene induces phosphorylation of histone H2AX2008
- Author(s)
  T.Toyooka, G.Ohnuki and Y.Ibuki
- Journal Title
  
  Mutation Research 650
  
  Pages: 132-139
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18710054
[Journal Article] UVB-Exposed Chlorinated Bisphenol A Generates Phosphorylated Histone H2AX in Human Skin Cells.2008
- Author(s)
  Y. Ibuki, Y. Tani, T. Toyooka
- Journal Title
  
  Chem. Res. Toxicol. 21
  
  Pages: 1770-1776
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19510071
[Journal Article] Generation of phosphorylated histone H2AX by benzene metabolites2008
- Author(s)
  M. Ishihama, T. Toyooka, Y. Ibuki
- Journal Title
  
  Toxicol. In Vitro 22
  
  Pages: 1861-1868
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19510071
[Journal Article] Solar-simulated light-exposed benzo[a]pyrene induces phosphorylation of histone H2AX2008
- Author(s)
  T.Toyooka, G.Ohnuki and Y. Ibuki
- Journal Title
  
  Mutat. Res 650(2)
  
  Pages: 132-139
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19510071
[Journal Article] UVB-Exposed Chlorinated Bisphenol A Generates Phosphorylated Histone H2AX in Human Skin Cells2008
- Author(s)
  Y. Ibuki, Y. Tani, T. Toyooka
- Journal Title
  
  Chem. Res. Toxicol 21(9)
  
  Pages: 1770-1776
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19510071
[Journal Article] Simple easy method to evaluate uptake potential of nanoparticles in mammalian cells using a flow cytometric light scatter analysis2007
- Author(s)
  H.Suzuki, T.Toyooka and Y.I buki
- Journal Title
  
  Environmental Science and Technology 41
  
  Pages: 3018-3024
- NAID
  130007003771
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18710054
[Journal Article] Water soluble fraction of solar-simulated light-exposed crude oil generates phosphorylation of histone H2AX in human skin cells under UVA exposre2007
- Author(s)
  Y.Ibuki, T.Toyooka, J.Shirah ata, T.Ohura and R.Goto
- Journal Title
  
  Environmental and Molecular Mutagenesis 48
  
  Pages: 430-490
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18710054
[Journal Article] DNA damage induced by coexposure to PAHs and light.A mini-review2007
- Author(s)
  T.Toyooka and Y.Ibuki
- Journal Title
  
  Environmetal Toxicology and Pharmacology 23
  
  Pages: 256-263
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18710054
[Journal Article] Hydrogen peroxicide is critical for UV-induced apoptosis inhibition2006
- Author(s)
  Y.Ibuki, M.Akaike, T.Toyooka, T.Mori, T.Nakayama, R.Goto
- Journal Title
  
  Redox Report 11
  
  Pages: 53-60
- Data Source
  KAKENHI-PROJECT-18710054
[Journal Article] Coexposure to benzo[a]pyrene and UVA induces DNA damage; First proof of double-strand breaks in a cell-free system2006
- Author(s)
  T.Toyooka, Y.Ibuki, F.Takabayashi, R.Goto
- Journal Title
  
  Environmental Molecular Mutagenesis 47
  
  Pages: 38-47
- Data Source
  KAKENHI-PROJECT-18710054
[Journal Article] New method for testing phototoxicity of polycyclic aromatic hydrocarbons2006
- Author(s)
  T.Toyooka, Y.Ibuki
- Journal Title
  
  Environmental Science ＆ Technology 40
  
  Pages: 3603-3608
- Data Source
  KAKENHI-PROJECT-18710054
[Journal Article] Inhibition of apoptosis by menadion on exposure to UVA.2006
- Author(s)
  Y.Ibuki, T.Toyooka, R.Goto
- Journal Title
  
  Cell Biology ＆ Toxicology. 22
  
  Pages: 351-360
- Data Source
  KAKENHI-PROJECT-18710054
[Patent] ヒストン高アセチル化状態における光増感処理による腫瘍殺傷方法2008
- Inventor(s)
  豊岡達士, 伊吹裕子
- Industrial Property Rights Holder
  静岡県立大学
- Industrial Property Number
  2008-307283
- Filing Date
  2008-12-01
- Data Source
  KAKENHI-PROJECT-19510071
[Patent] ヒストン高アセチル化状態における光増感処理による腫瘍殺傷方法
- Inventor(s)
  豊岡達士、伊吹裕子
- Industrial Property Number
  2008-307283
- Data Source
  KAKENHI-PROJECT-19510071
[Presentation] 二要素(取込み量＋毒性)同時解析による新規ナノマテリアルリスク評価法の開発2016
- Author(s)
  豊岡達士，趙暁旭, 三浦信彦, 伊吹裕子，王瑞生
- Organizer
  日本毒性学会
- Place of Presentation
  名古屋
- Year and Date
  2016-06-29
- Data Source
  KAKENHI-PROJECT-15H06893
[Presentation] 二要素(取込み量+毒性)同時解析によるナノマテリアルリスク評価法の開発2016
- Author(s)
  豊岡達士、趙暁旭、伊吹裕子、王瑞生
- Organizer
  日本毒性学会
- Place of Presentation
  名古屋
- Year and Date
  2016-07-01
- Data Source
  KAKENHI-PROJECT-15H06893
[Presentation] 環境化学物質の光分解と遺伝毒性変化：リン酸化ヒストンＨ２ＡＸを指標とした解析2014
- Author(s)
  伊吹裕子、豊岡達士
- Organizer
  日本薬学会134年会
- Place of Presentation
  熊本
- Invited
- Data Source
  KAKENHI-PROJECT-24510084
[Presentation] NNKによるヒストン修飾変化とCYP2A13による代謝活性化との関連性2013
- Author(s)
  四方真理子, 豊岡達士, 伊吹裕子
- Organizer
  第４２回日本環境変異原学会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-24510084
[Presentation] 17-β-Estradiolによるヒストンアセチル化とDNA損傷修復応答変化2013
- Author(s)
  伊吹裕子, 豊岡達士, 松下実理
- Organizer
  第３５回日本光医学・光生物学会
- Place of Presentation
  浜松
- Data Source
  KAKENHI-PROJECT-24510084
[Presentation] 銀ナノ粒子による紫外線誘導DNA損傷の増強2013
- Author(s)
  趙暁旭, 豊岡達士, 伊吹裕子
- Organizer
  第40回日本毒性学会学術年会
- Place of Presentation
  幕張
- Data Source
  KAKENHI-PROJECT-24510084
[Presentation] 光毒性評価指標としてのリン酸化ヒストンH2AXの有用性の検証2013
- Author(s)
  豊岡達士, 伊吹裕子
- Organizer
  第３５回日本光医学・光生物学会
- Place of Presentation
  浜松
- Data Source
  KAKENHI-PROJECT-24510084
[Presentation] 17-β-estradiol-induced hyperacetylation of histone H3 and change of sensitivity to UVB.2013
- Author(s)
  Yuko Ibuki, Tatsushi Toyooka, Guang Yang, Misato Matsushita
- Organizer
  The 6th Asia & Oceania Conference on Photobiology
- Place of Presentation
  Sydeny
- Data Source
  KAKENHI-PROJECT-24510084
[Presentation] NNKによるヒストン修飾変化とCYP2A6/2A13による代謝活性との関連性2013
- Author(s)
  四方真理子, 豊岡達士, 伊吹裕子
- Organizer
  第40回日本毒性学会学術年会
- Place of Presentation
  幕張
- Data Source
  KAKENHI-PROJECT-24510084
[Presentation] ノニルフェノールポリエトキシレートはどのようにしてDNA二本鎖切断を誘導するのか2013
- Author(s)
  豊岡達士, 伊吹裕子
- Organizer
  第40回日本毒性学会学術年会
- Place of Presentation
  幕張
- Data Source
  KAKENHI-PROJECT-24510084
[Presentation] ノニルフェノールポリエトキシレートによるDNA二本鎖切断誘導メカニズムの解明2013
- Author(s)
  豊岡達士, 久保田徹, 伊吹裕子
- Organizer
  第４２回日本環境変異原学会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-24510084
[Presentation] Formaldehyde-induced histone modifications and expression of proto-oncogenes.2012
- Author(s)
  Ikuma Yoshida, Tatsushi Toyooka, Yuko Ibuki
- Organizer
  The 6th International Congress of Asian Society of Toxicology
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-24510084
[Presentation] たばこ副流煙によるヒストン修飾変化2012
- Author(s)
  伊吹裕子, 豊岡達士
- Organizer
  第39回日本毒性学会学術年会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-24510084
[Presentation] ヒストンH2AX のリン酸化を指標とした化学物質の遺伝毒性検出2012
- Author(s)
  豊岡達士、伊吹裕子
- Organizer
  第41回日本環境変異原学会
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-22710065
[Presentation] ホルムアルデヒドによる発がんとヒストン修飾変化の関連性について2012
- Author(s)
  吉田唯真, 豊岡達士、伊吹裕子
- Organizer
  第２５回変異機構研究会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-24510084
[Presentation] ホルムアルデヒドによるヒストン修飾変化と前がん遺伝子発現制御2012
- Author(s)
  吉田唯真, 豊岡達士、伊吹裕子
- Organizer
  環境エピゲノム研究会第７回定例会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24510084
[Presentation] 銀は紫外線誘導ヒストンH2AXのリン酸化を増強する2012
- Author(s)
  趙暁旭, 豊岡達士, 伊吹裕子
- Organizer
  第４１回日本環境変異原学会
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-24510084
[Presentation] α, β-不飽和アルデヒドによるヒストン修飾変化2012
- Author(s)
  吉田唯真, 豊岡達士, 伊吹裕子
- Organizer
  第４１回日本環境変異原学会
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-24510084
[Presentation] 17-β-estradiolによるヒストンアセチル化と紫外線感受性変化2012
- Author(s)
  松下実理, 豊岡達士, 伊吹裕子
- Organizer
  第４１回日本環境変異原学会
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-24510084
[Presentation] タバコ煙中発がん性物質NNKによるヒストン修飾変化と発がんプロモーション活性.2012
- Author(s)
  四方真理子, 豊岡達士, 伊吹裕子
- Organizer
  第４１回日本環境変異原学会
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-24510084
[Presentation] ヒストンH2AXのリン酸化を指標とした化学物質の遺伝毒性検出2012
- Author(s)
  豊岡達士, 伊吹裕子
- Organizer
  第４１回日本環境変異原学会
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-24510084
[Presentation] ホルムアルデヒドによるヒストン修飾変化とがん原遺伝子発現制御2012
- Author(s)
  吉田唯真, 豊岡達士、伊吹裕子
- Organizer
  第39回日本毒性学会学術年会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-24510084
[Presentation] 化学物質によるヒストン修飾変化とそれを指標とした毒性評価系の構築2012
- Author(s)
  伊吹裕子,四方真理子,吉田唯真,豊岡達士, 若林敬二
- Organizer
  第２７回発癌病理研究会
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-24510084
[Presentation] ノニルフェノールポリエトキシレート及びその光分解物によるリン酸化ヒストンH2AX の誘導2011
- Author(s)
  豊岡達士、久保田徹、伊吹裕子
- Organizer
  第38回日本トキシコロジー学会学術年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22710065
[Presentation] ノニルフェノールポリエトキシレートはヒストンH2AX のリン酸化を誘導する2011
- Author(s)
  豊岡達士、久保田徹、伊吹裕子
- Organizer
  第40回日本環境変異原学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22710065
[Presentation] 塩素化ビスフェノールAによるヒストン修飾変化2011
- Author(s)
  松下実里, 豊岡達士, 伊吹裕子
- Organizer
  富士山麓アカデミック&サイエンスフェア
- Place of Presentation
  静岡
- Year and Date
  2011-12-13
- Data Source
  KAKENHI-PROJECT-21510071
[Presentation] ノニルフェノールポリエトキシレートはヒストンH2AXのリン酸化を誘導する2011
- Author(s)
  豊岡達士, 久保田徹, 伊吹裕子
- Organizer
  第40回日本環境変異原学会
- Place of Presentation
  東京
- Year and Date
  2011-11-21
- Data Source
  KAKENHI-PROJECT-21510071
[Presentation] ノニルフェノールポリエトキシレート及びその光分解物はヒストンH2AXのリン酸化を誘導する2011
- Author(s)
  豊岡達士
- Organizer
  日本トキシコロジー学会
- Place of Presentation
  横浜
- Year and Date
  2011-07-13
- Data Source
  KAKENHI-PROJECT-22710065
[Presentation] ホルムアルデヒドによるヒストン修飾変化2011
- Author(s)
  吉田唯真, 豊岡達士, 伊吹裕子
- Organizer
  第40回日本環境変異原学会
- Place of Presentation
  東京
- Year and Date
  2011-11-21
- Data Source
  KAKENHI-PROJECT-21510071
[Presentation] ヒストンH2AXのリン酸化を指標とした光毒性検出法2011
- Author(s)
  伊吹裕子, 豊岡達士
- Organizer
  第38回トキシコロジー学術大会
- Place of Presentation
  横浜
- Year and Date
  2011-07-13
- Data Source
  KAKENHI-PROJECT-21510071
[Presentation] ノニルフェノールポリエトキシレート及びその光分解物によるリン酸化ヒストンH2AXの誘導2011
- Author(s)
  豊岡達士, 久保田徹, 伊吹裕子
- Organizer
  第24回変異機構研究会
- Place of Presentation
  愛知
- Year and Date
  2011-07-09
- Data Source
  KAKENHI-PROJECT-21510071
[Presentation] ノニルフェノールポリエトキシレート及びその光分解物はヒストンH2AXのリン酸化を誘導する2011
- Author(s)
  豊岡達士, 久保田徹, 伊吹裕子
- Organizer
  第38回トキシコロジー学術大会
- Place of Presentation
  横浜
- Year and Date
  2011-07-11
- Data Source
  KAKENHI-PROJECT-21510071
[Presentation] ナノ粒子取り込み量と細胞内活性酸素種量の二要素同時解析によるナノ毒性評価法の構築2011
- Author(s)
  戸塚洋輔、豊岡達士、伊吹裕子
- Organizer
  第40回日本環境変異原学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22710065
[Presentation] ホルムアルデヒドと発がん-ヒストン化学修飾の変化に着目した新たながん発症機構の解明-2011
- Author(s)
  吉田唯真, 豊岡達士, 伊吹裕子
- Organizer
  富士山麓アカデミック&サイエンスフェア
- Place of Presentation
  静岡
- Year and Date
  2011-12-13
- Data Source
  KAKENHI-PROJECT-21510071
[Presentation] 銀ナノ粒子と紫外線UVA の組み合わせによる高い殺菌効果とそれに伴うヒトへの毒性2011
- Author(s)
  趙暁旭、豊岡達士、伊吹裕子
- Organizer
  第24回変異機構研究会
- Place of Presentation
  愛知
- Data Source
  KAKENHI-PROJECT-22710065
[Presentation] p21-GFP 蛍光を指標としたFlowcytometer によるナノ粒子毒性評価系の構築2011
- Author(s)
  戸塚洋輔、豊岡達士、小池学、伊吹裕子
- Organizer
  第24回変異機構研究会
- Place of Presentation
  愛知
- Data Source
  KAKENHI-PROJECT-22710065
[Presentation] 銀ナノ粒子はDNA-topoisomerase II複合体を形成しヒストンH2AXのリン酸化を誘導する2010
- Author(s)
  豊岡達士、伊吹裕子
- Organizer
  第39回日本環境変異原学会
- Place of Presentation
  茨城
- Year and Date
  2010-11-16
- Data Source
  KAKENHI-PROJECT-21510071
[Presentation] 銀ナノ粒子はDNA-topoisomerase II複合体形成しヒストンH2AXのリン酸化を誘導する2010
- Author(s)
  豊岡達士、伊吹裕子
- Organizer
  第23回変異原研究会夏の学校
- Place of Presentation
  愛知
- Year and Date
  2010-07-11
- Data Source
  KAKENHI-PROJECT-21510071
[Presentation] p21-GFP を指標としたFlow cytometer による新規ナノ粒子評価法の開発2010
- Author(s)
  戸塚洋輔、豊岡達士、小池学、伊吹裕子
- Organizer
  第39回日本環境変異原学会
- Place of Presentation
  筑波
- Data Source
  KAKENHI-PROJECT-22710065
[Presentation] p21を指標としたFlow Cytometerによる新規ナノ粒子毒性評価法の開発2010
- Author(s)
  戸塚洋輔、豊岡達士、小池学、伊吹裕子
- Organizer
  第39回日本環境変異原学会
- Place of Presentation
  つくば
- Year and Date
  2010-11-16
- Data Source
  KAKENHI-PROJECT-21510071
[Presentation] 乳がん細胞におけるエストロゲン代謝物のDNA損傷に対するカテコールアミンの影響2010
- Author(s)
  山崎隼輔、榊原啓之、豊岡達士、伊吹裕子、竹村ひとみ、下位香代子
- Organizer
  第39回日本環境変異原学会
- Place of Presentation
  つくば
- Year and Date
  2010-11-16
- Data Source
  KAKENHI-PROJECT-21510071
[Presentation] 銀ナノ粒子はtopoisomerase II 複合体を形成しヒストンH2AX のリン酸化を誘導する2010
- Author(s)
  豊岡達士、伊吹裕子
- Organizer
  第39回日本環境変異原学会
- Place of Presentation
  筑波
- Data Source
  KAKENHI-PROJECT-22710065
[Presentation] 銀ナノ粒子はtopoisomerase II複合体を形成しヒストンH2AXのリン酸化を誘導する2010
- Author(s)
  豊岡達士
- Organizer
  日本環境変異原学会
- Place of Presentation
  筑波
- Year and Date
  2010-11-16
- Data Source
  KAKENHI-PROJECT-22710065
[Presentation] 銀ナノ粒子はDNA-topoisomerase II複合体を形成しヒストンH2AXのリン酸化を誘導する2010
- Author(s)
  豊岡達士、伊吹裕子
- Organizer
  第39回日本環境変異原学会
- Place of Presentation
  つくば
- Year and Date
  2010-11-16
- Data Source
  KAKENHI-PROJECT-21510071
[Presentation] 太陽光中の高波長領域紫外線(UVA1)がUVBの誘導する細胞死およびDNA損傷に及ぼす影響2009
- Author(s)
  伊吹裕子, 豊岡達士
- Organizer
  第31回日本光医学・光生物学会
- Place of Presentation
  大阪
- Year and Date
  2009-07-24
- Data Source
  KAKENHI-PROJECT-21510071
[Presentation] Histone deacetylase inhibitor, sodium butyrate enhances the cell-killing effect of PUVA by attenuating necleotide excision repair2009
- Author(s)
  豊岡達士、伊吹裕子
- Organizer
  第10 回静岡ライフサイエンスシンポジウム記念大会
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-19510071
[Presentation] Histone deacetylase inhibitor, sodium butyrate enhances the cell-killing effect of PUVA by attenuating nucleotide excision repair2009
- Author(s)
  豊岡達士, 伊吹裕子
- Organizer
  第31回日本光医学・光生物学会
- Place of Presentation
  大阪
- Year and Date
  2009-07-25
- Data Source
  KAKENHI-PROJECT-21510071
[Presentation] Histone deacetylase inhibitor, sodium butyrate enhances the cell-killingeffect of PUVA by attenuating nucleotide excision repair.2009
- Author(s)
  豊岡達士, 伊吹裕子
- Organizer
  第10回静岡ライフサイエンスシンポジウム記念大会
- Place of Presentation
  静岡
- Year and Date
  2009-03-06
- Data Source
  KAKENHI-PROJECT-19510071
[Presentation] Silver nanoparticles induce phosphorylation of histone H2AX by inhibition of topoisomerase II2009
- Author(s)
  Tatsushi Toyooka, Yuko Ibuki
- Organizer
  第82回日本生化学会
- Place of Presentation
  神戸
- Year and Date
  2009-10-22
- Data Source
  KAKENHI-PROJECT-21510071
[Presentation] 銀ナノ粒子は topoisomerase IIの阻害を介してヒストンH2AXのリン酸化を誘導する2009
- Author(s)
  豊岡達士, 伊吹裕子
- Organizer
  第38回日本環境変異原学会
- Place of Presentation
  静岡
- Year and Date
  2009-11-26
- Data Source
  KAKENHI-PROJECT-21510071
[Presentation] UVA irradiation enhcnaces phosphorylation if histone H2AX induced by 9, 10-phenantherenquinone.2008
- Author(s)
  Shinmen T, Toyooka T, Ibuki Y
- Organizer
  第37回日本環境変異原学会
- Place of Presentation
  沖縄
- Year and Date
  2008-12-05
- Data Source
  KAKENHI-PROJECT-19510071
[Presentation] UVA irradiation enhcnaces phosphorylation if histone H2AX induced by 9,10-phenantherenquinone2008
- Author(s)
  Shinmen T, Toyooka T, Ibuki Y
- Organizer
  第37 回日本環境変異原学会
- Place of Presentation
  沖縄
- Data Source
  KAKENHI-PROJECT-19510071
[Presentation] UVB-exposed chlorinated bisphenol A generates phosphorylated histone H2AX in human skin cells2008
- Author(s)
  Ibuki Y, Tani Y, Toyooka T
- Organizer
  第37 回日本環境変異原学会
- Place of Presentation
  沖縄
- Data Source
  KAKENHI-PROJECT-19510071
[Presentation] UVB-exposed chlorinated bisphenol A generates phosphorylated histone H2AX in human skin cells.2008
- Author(s)
  Ibuki Y, Tani Y, Toyooka T
- Organizer
  第37回日本環境変異原学会
- Place of Presentation
  沖縄
- Year and Date
  2008-12-05
- Data Source
  KAKENHI-PROJECT-19510071
[Presentation] Solar-stimulated light-exposed benzo[a]pyrene induces phosphorylation of histone H2AX2007
- Author(s)
  T.Toyooka, M.Koike, Y.Ibuki
- Organizer
  環境変異原学会
- Place of Presentation
  福岡小倉
- Year and Date
  2007-11-30
- Data Source
  KAKENHI-PROJECT-18710054
[Presentation] 光修飾を受けた多環芳香族炭化水素によるアポトーシスの阻害と発がんの関連性2007
- Author(s)
  寺西麻衣、豊岡達士、伊吹裕子
- Organizer
  第29 回日本光医学・光生物学会
- Place of Presentation
  富山
- Data Source
  KAKENHI-PROJECT-19510071
[Presentation] Solar-simulated light-exposed benzo[a]pyrene induces phosphorylation of histone H2AX2007
- Author(s)
  Tatsushi Toyooka, Go Ohunuki, Yuko Ibuki
- Organizer
  1th Asian Conference on Environmenta1 Mutagens
- Place of Presentation
  福岡
- Year and Date
  2007-11-29
- Data Source
  KAKENHI-PROJECT-19510071
[Presentation] Benzo[a]pyrene の光反応中間体によるDNA二本鎖切断およびヒストンH2AX のリン酸化の誘発2007
- Author(s)
  大貫剛、豊岡達士、伊吹裕子
- Organizer
  第34 回日本トキシコロジー学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19510071
[Presentation] 疑似太陽光照射したBenzo[a]pyrene の光照射産物によるヒストンH2AX のリン酸の誘導2007
- Author(s)
  大貫剛、豊岡達士、伊吹裕子
- Organizer
  変異機構研究会・第20 回夏の学校
- Place of Presentation
  愛知
- Data Source
  KAKENHI-PROJECT-19510071
[Presentation] Benzo[a]pyreneの光反応中間体によるDNA二本鎖切断およびヒストンH2AXのリン酸化の誘発2007
- Author(s)
  大貫剛、豊岡達士、伊吹裕子
- Organizer
  第34回日本トキシコロジー学会
- Place of Presentation
  東京
- Year and Date
  2007-06-28
- Data Source
  KAKENHI-PROJECT-19510071
[Presentation] 化学物質の光毒性検出におけるリン酸化ヒストンH2AX の有用性2007
- Author(s)
  豊岡達士、伊吹裕子
- Organizer
  第29 回日本光医学・光生物学会
- Place of Presentation
  富山
- Data Source
  KAKENHI-PROJECT-19510071
[Presentation] 化学物質の光毒性検出におけるリン酸化ヒストンH2AXの有用性2007
- Author(s)
  豊岡達士、伊吹裕子
- Organizer
  第29回日本光医学・光生物学会
- Place of Presentation
  富山
- Year and Date
  2007-07-14
- Data Source
  KAKENHI-PROJECT-19510071
[Presentation] Solar-simulated light-exposed benzo[a]pyrene induces phosphorylation of histone H2AX2007
- Author(s)
  Toyooka T, Ohunuki G, Ibuki Y
- Organizer
  1th Asian Conference on Environmental Mutagens
- Place of Presentation
  Fukuoka
- Data Source
  KAKENHI-PROJECT-19510071
[Presentation] 多環芳香族炭化水素の光反応中間体によるアポトーシスの阻害と発がんの関連性2007
- Author(s)
  寺西麻衣、豊岡達士、伊吹裕子
- Organizer
  第34回日本トキシコロジー学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19510071
[Presentation] 長波長紫外線（365 nm-UVA）の変異誘発傷害とその修復機構
- Author(s)
  樊星、有元佐賀惠、豊岡達士、伊吹裕子、趙暁旭、鈴木利典、根岸友惠
- Organizer
  第43回日本環境変異原学会
- Place of Presentation
  東京
- Year and Date
  2014-12-04 – 2014-12-05
- Data Source
  KAKENHI-PROJECT-24510084
[Presentation] ノニルフェノールポリエトキシレート作用によって誘導されるDNA二本鎖切断とその誘導メカニズムの解明
- Author(s)
  豊岡達士, 久保田徹, 伊吹裕子
- Organizer
  第26回変異原機構研究会
- Place of Presentation
  愛知
- Data Source
  KAKENHI-PROJECT-24510084
[Presentation] たばこの煙に含まれるNNKは発がん促進の原因となる
- Author(s)
  四方真理子, 豊岡達士, 伊吹裕子
- Organizer
  富士山麓アカデミック&サイエンスフェア
- Place of Presentation
  沼津
- Data Source
  KAKENHI-PROJECT-24510084
[Presentation] NNKによるヒストン修飾変化とCYP2A6/2A13による代謝活性化との関連性
- Author(s)
  四方真理子, 豊岡達士, 伊吹裕子
- Organizer
  第26回変異原機構研究会
- Place of Presentation
  愛知
- Data Source
  KAKENHI-PROJECT-24510084
[Presentation] 女性ホルモン投与は安全か- E2暴露による紫外線感受性の上昇とDNA損傷修復の変化
- Author(s)
  楊光, 豊岡達士, 伊吹裕子
- Organizer
  富士山麓アカデミック&サイエンスフェア
- Place of Presentation
  沼津
- Data Source
  KAKENHI-PROJECT-24510084
[Presentation] 長波長紫外線（365 nm-UVA）の変異誘発傷害とその修復機構
- Author(s)
  樊星、有元佐賀惠、豊岡達士、伊吹裕子、亀井保博、根岸友惠
- Organizer
  第36回日本光医学・光生物学会
- Place of Presentation
  大阪
- Year and Date
  2014-07-24 – 2014-07-25
- Data Source
  KAKENHI-PROJECT-24510084

1. IBUKI Yuko (30236781)

# of Collaborated Projects: 6 results

# of Collaborated Products: 104 results
2. OOURA Takeshi (60315851)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. Miura Nobuhiko (20229644)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. Wang Rui-sheng (10321895)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results

Toyooka Tatsushi 豊岡 達士

TOYOOKA Tatsushi 豊岡 達士

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Development of new method for risk assessment of nanomaterials by concurrent analysis of uptake potential and toxicity using flowcytometerPrincipal Investigator

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ヒストン修飾変化の観点より迫る農薬による紫外線発がん増強の可能性Principal Investigator

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Relationship between coexposure to chemicals and UV, and recent increase of skin cancer - from a view point of histone modifications

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Augmentation of UV-induced carcinogenesis by heavy metals-relationships with histone modification and repair of DNA damagePrincipal Investigator

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Effect of combined exposures to multiple chemicals and ultraviolet rays on recent increase of skin cancer-from a view point of histone modifications

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Multiple effects of environmental pollutants and ultraviolet light on the recent increase of skin cancer -relationship with histone modification

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生体内分子に着目した高感度環境影響評価法の構築Principal Investigator

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[Journal Article] Silver nanoparticle-induced phosphorylation of histone H3 at serine 10 is due to dynamic changes in actin filaments and the activation of Aurora kinases.2017

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[Journal Article] 1,2-Dichloropropane generates phosphorylated histone H2AX via cytochrome P450 2E1-mediated metabolism.2017

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[Journal Article] Effect of physicochemical character differences on the genotoxic potency of kaolin.2017

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[Journal Article] Evaluation of chemical phototoxicity, focusing on phosphorylated histone H2AX2015

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NAID

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[Journal Article] γ-H2AX induced by linear alkylbenzene sulfonates is due to deoxyribonuclease-1 translocation to the nucleus via actin disruption.2015

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[Journal Article] Cigarette sidestream smoke induces histone H3 phosphorylation via JNK and PI3K/Akt pathways, leading to the expression of proto-oncogenes.2014

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[Journal Article] ヒストンH2AXのリン酸化に着目した光毒性評価2014

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Toyooka Tatsushi 豊岡達士

TOYOOKA Tatsushi 豊岡達士