Matsumoto Shin-Ei 松本信英

… Alternative Names

MATSUMOTO Shinei 松本信英

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Researcher Number	40432950
Other IDs	https://orcid.org/0000-0002-4283-202X
Affiliation (Current)	2025: 鹿児島大学, 医歯学域医学系, 助教
Affiliation (based on the past Project Information) *help	2016 – 2024: 鹿児島大学, 医歯学域医学系, 助教 2015: 順天堂大学, 医学研究科, 助教 2013 – 2015: 順天堂大学, 医学(系)研究科(研究院), 助教 2009: 大学院・医学研究科, 助教 2009: 順天堂大学, 大学院・医学研究科, 助教
Review Section/Research Field	Principal Investigator Basic Section 49070:Immunology-related / Basic Section 51030:Pathophysiologic neuroscience-related / Neurology Except Principal Investigator Basic Section 57080:Social dentistry-related / Immunology / Biological Sciences
Keywords	Principal Investigator TREM2 / 神経変性疾患 / 認知症 / 伝播 / ミクログリア / タウオパチー / 炎症 / マクロファージ / タウ / 神経科学 / アルツハイマー / 免疫系 / アルツハイマー病 … More Except Principal Investigator … More アルツハイマー病 / オートファジー / 免疫 / ワクチン / アミロイド / 神経細胞 / 口腔機能低下 / 老化 / 海馬 / 青斑核 / 歯の喪失 / 加齢 / 三叉神経 / TDP-43 / 認知機能 / 抜歯 / 三叉神経中脳路核 / アミロイドβ / 炎症 / Ｔ細胞 / アミロイドベータ / 老人班 / 老人斑 / amyloid / 十全大補湯 / モノクローナル抗体 / ミクログリア / 漢方薬 Less

コロニー刺激因子受容体非依存的・TREM2依存的な未知のマクロファージ分化機構の解明Principal Investigator
- Principal Investigator
  
  松本信英
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49070:Immunology-related
- Research Institution
  Kagoshima University
Elucidation of the mechanism by which aging-induced deterioration of oral function is involved in the development of Alzheimer's disease.
- Principal Investigator
  
  後藤哲哉
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57080:Social dentistry-related
- Research Institution
  Kagoshima University
Elucidation of the molecular mechanism by which neurodegeneration caused by tooth loss initiates Alzheimer's disease
- Principal Investigator
  
  GOTO Tetsuya
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57080:Social dentistry-related
- Research Institution
  Kagoshima University
The role of microglia in the propagation of tau aggregatesPrincipal Investigator
- Principal Investigator
  
  Matsumoto Shin-Ei
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 51030:Pathophysiologic neuroscience-related
- Research Institution
  Kagoshima University
The role of Alzheimer's disease risk factors in the tauopathy propagation model.Principal Investigator
- Principal Investigator
  
  Matsumoto Shin-Ei
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Kagoshima University
A study of T cell-mediated chronic inflammation in Alzheimer model mice
- Principal Investigator
  
  TABIRA Takeshi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  Juntendo University
Analysis of immune mechanisms of Alzheimer's disease and development of a novel treatment
- Principal Investigator
  
  TABIRA Takeshi
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Juntendo University
  National Institute for Longevity Sciences,NCGG

All 2023 2022 2021 2020 2018 2017

All Journal Article Presentation

[Journal Article] Reduced Autophagy in Aged Trigeminal Neurons Causes Amyloid β Diffusion2023
- Author(s)
  Sonoda R、Kuramoto E、Minami S、Matsumoto SE、Ohyagi Y、Saito T、Saido T、Noguchi K、Goto T.
- Journal Title
  
  Journal of Dental Research
  
  Volume: - Issue: 8 Pages: 938-946
- DOI
  10.1177/00220345231156095
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07826, KAKENHI-PROJECT-20K10296, KAKENHI-PROJECT-22K19636, KAKENHI-PROJECT-22K10039, KAKENHI-PROJECT-23K06886
[Journal Article] Development of a system to analyze oral frailty associated with Alzheimer's disease using a mouse model.2022
- Author(s)
  Kuramoto E, Kitawaki A, Yagi T, Kono H, Matsumoto SE, Hara H, Ohyagi Y, Iwai H, Yamanaka A, Goto T.
- Journal Title
  
  Front Aging Neurosci.
  
  Volume: 14 Pages: 935033-935033
- DOI
  10.3389/fnagi.2022.935033
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09916, KAKENHI-PROJECT-22K19636, KAKENHI-PROJECT-19K10047, KAKENHI-PROJECT-19K10058, KAKENHI-PROJECT-20K07826, KAKENHI-PROJECT-20K10296
[Journal Article] Neurodegeneration of trigeminal mesencephalic neurons by the tooth loss triggers the progression of Alzheimer's disease in 3xTg-AD model mice.2020
- Author(s)
  Goto T, Kuramoto E, Dhar A, Wang RP-H, Seki H, Iwai H, Yamanaka A, Matsumoto S, Hara H, Michikawa M, Ohyagi Y, Leung WK, Chang RC-C
- Journal Title
  
  Journal of Alzheimer's Disease
  
  Volume: 76 Issue: 4 Pages: 1443-1459
- DOI
  10.3233/jad-200257
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07826, KAKENHI-PROJECT-20K07861, KAKENHI-PROJECT-20K10296, KAKENHI-PLANNED-17H06311
[Presentation] Characterization of lipid-induced macrophages derived from bone marrow2021
- Author(s)
  松本信英
- Organizer
  9th ITAM workshop
- Data Source
  KAKENHI-PROJECT-19K07825
[Presentation] 三叉神経中脳路核の神経変性によるアミロイドβオリゴマーの拡散について2021
- Author(s)
  園田怜美, 倉本恵梨子, 松本信英, 原博満, 大八木保政, 野口和行, 後藤哲哉 .
- Organizer
  日本認知症学会
- Data Source
  KAKENHI-PROJECT-20K10296
[Presentation] 3xTg-ADマウスにおける神経細胞内アミロイドβの加齢変化について2020
- Author(s)
  園田怜美、倉本恵梨子、松本信英、原　博満、大八木保政、野口和行、後藤哲哉
- Organizer
  第39回日本認知症学術集会
- Data Source
  KAKENHI-PROJECT-20K10296
[Presentation] アルツハイマー病のリスクバリアントTREM2 R47Hノックインマウスの樹立2018
- Author(s)
  松本信英、立部誉、原博満
- Organizer
  鹿児島神経科学研究会第11回研究発表会
- Data Source
  KAKENHI-PROJECT-16K09680
[Presentation] 3xTg-ADモデルマウスの病態におけるTREM2の役割2017
- Author(s)
  松本信英
- Organizer
  認知症研究を知る若手研究者の集まり2017
- Data Source
  KAKENHI-PROJECT-16K09680

1. TABIRA Takeshi (80112332)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. GOTO Tetsuya (70253458)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
3. 白方良典 (60359982)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. 倉本恵梨子 (60467470)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
5. TAKAHASHI Keikichi (40117148)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. HARA Hideo (00260381)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. SEKIYAMA Atsuo (30403702)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 大八木保政 (30301336)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results

Matsumoto Shin-Ei 松本 信英

MATSUMOTO Shinei 松本 信英

Research Projects

Research Products

Co-Researchers

コロニー刺激因子受容体非依存的・TREM2依存的な未知のマクロファージ分化機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the mechanism by which aging-induced deterioration of oral function is involved in the development of Alzheimer's disease.

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the molecular mechanism by which neurodegeneration caused by tooth loss initiates Alzheimer's disease

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The role of microglia in the propagation of tau aggregatesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The role of Alzheimer's disease risk factors in the tauopathy propagation model.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A study of T cell-mediated chronic inflammation in Alzheimer model mice

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of immune mechanisms of Alzheimer's disease and development of a novel treatment

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Reduced Autophagy in Aged Trigeminal Neurons Causes Amyloid β Diffusion2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Development of a system to analyze oral frailty associated with Alzheimer's disease using a mouse model.2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Neurodegeneration of trigeminal mesencephalic neurons by the tooth loss triggers the progression of Alzheimer's disease in 3xTg-AD model mice.2020

Author(s)

Journal Title

DOI

Data Source

[Presentation] Characterization of lipid-induced macrophages derived from bone marrow2021

Author(s)

Organizer

Data Source

[Presentation] 三叉神経中脳路核の神経変性によるアミロイドβオリゴマーの拡散について2021

Author(s)

Organizer

Data Source

[Presentation] 3xTg-ADマウスにおける神経細胞内アミロイドβの加齢変化について2020

Author(s)

Organizer

Data Source

[Presentation] アルツハイマー病のリスクバリアントTREM2 R47Hノックインマウスの樹立2018

Author(s)

Organizer

Data Source

[Presentation] 3xTg-ADモデルマウスの病態におけるTREM2の役割2017

Author(s)

Matsumoto Shin-Ei 松本信英

MATSUMOTO Shinei 松本信英