YAMAGUCHI Naohiro 山口尚宏

Researcher Number	40432976
External Links
Affiliation (based on the past Project Information) *help	2019: 長崎大学, 医歯薬学総合研究科(医学系), 助教 2016: 長崎大学, 医歯薬学総合研究科(医学系), 助教 2014 – 2015: 長崎大学, 病院(医学系), 医員 2010: Nagasaki University, 病院, 医員 2010: 長崎大学, 病院消化器内科, 助教 2008 – 2009: Nagasaki University, 大学院・医歯薬学総合研究科, 助教
Review Section/Research Field	Principal Investigator Basic Section 52030:Psychiatry-related / Psychiatric science / Nerve anatomy/Neuropathology
Keywords	Principal Investigator 自殺 / リチウム / 衝動性 / 微量 / 低濃度 / うつ病 / 代謝型グルタミン酸受容体I型(mGluR1) / 蛍光共鳴エネルギー移動(FRET) / プリオン蛋白質PrP / 免疫沈降 … More / 細胞内Ca2+オーバーロード / mGluR1 / 代謝型グルタミン酸受容体 / 神経変性死 / Shadoo(sho) / Doppel(Dpl) / プリオン蛋白質(PrP) / プリオン / 神経変性疾患 Less

行動変容を起こす微量リチウム長期経口投与の作用機序解明へのアプローチPrincipal Investigator
- Principal Investigator
  
  山口尚宏
- Project Period (FY)
  2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52030:Psychiatry-related
- Research Institution
  Nagasaki University
Examination of the impulsivity change of mice administrated the long-term and low-concentrated lithium.Principal Investigator
- Principal Investigator
  
  YAMAGUCHI Naohiro
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  Nagasaki University
The molecular mechanism of the prion protein and the homolog which cause the neuro-degenerative/-protective function.Principal Investigator
- Principal Investigator
  
  YAMAGUCHI Naohiro
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Nagasaki University

All 2017 2015 2014 2011 2010 2009 2008 Other

All Journal Article Presentation

[Journal Article] Ultrasensitive human prion detection in cerebrospinal fluid by real-time quaking-induced conversion.2011
- Author(s)
  Atarashi R, Satoh K, Sano K, Fuse T, Yamaguchi N, Ishibashi D, Matsubara T, Nakagaki T, Yamanaka H, Shirabe S, Yamada M, Mizusawa H, Kitamoto T, Klug G, McGlade A, Collins SJ, Nishida N.
- Journal Title
  
  Nat Med. 17(2)
  
  Pages: 175-178
- NAID
  120006984771
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20500324
[Journal Article] Escherichia coli contamination of menstrual blood and effect of bacterial endotoxin on endometriosis.2010
- Author(s)
  Khan KN, Kitajima M, Hiraki K, Yamaguchi N, Katamine S, Matsuyama T, Nakashima M, Fujishita A, Ishimaru T, Masuzaki H.
- Journal Title
  
  Fertil Steril. 94(7)
- NAID
  120006984493
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20500324
[Journal Article] Human Papillomavirus DNA in Plasma of Patients with HPV16 DNA-positive Uterine Cervical Cancer.2010
- Author(s)
  Shimada T, Yamaguchi N, Nishida N, Yamasaki K, Miura K, Katamine S, Masuzaki H.
- Journal Title
  
  Jpn J Clin Oncol.
- NAID
  120006984483
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20500324
[Journal Article] A case of unilateral adrenal hyperplasia being difficult to distinguish from aldosterone-producing adenoma.2009
- Author(s)
  Shigematsu K, Yamaguchi N, Nakagaki T, Sakai H.
- Journal Title
  
  Exp Clin Endocrinol Diabetes. 117(3)
  
  Pages: 124-128
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20500324
[Journal Article] case of unilateral adrenal hyperplasia being difficult to distinguish from aldosterone-producing adenoma.2009
- Author(s)
  Shigematsu K, Yamaguchi N, Nakagaki T, Sakai H.
- Journal Title
  
  Exp Clin Endocrinol Diabetes. 117(3)
  
  Pages: 124-128
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20500324
[Journal Article] Analysis of mRNA expression for steroidogenic enzymes in the remaining adrenal cortices attached to adrenocortical adenomas.2008
- Author(s)
  Shigematsu K, Nakagaki T, Yamaguchi N, Kawai K, Sakai H, Takahara O.
- Journal Title
  
  Eur J Endocrinol. 158(6)
  
  Pages: 867-878
- NAID
  120006984107
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20500324
[Journal Article] Bone marrow stroma cells are susceptible to prion infection.2008
- Author(s)
  Takakura Y, Yamaguchi N, Nakagaki T, Satoh K, Kira J, Nishida N.
- Journal Title
  
  Biochem Biophys Res Commun. 377(3)
  
  Pages: 957-961
- NAID
  120006984617
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20500324
[Journal Article] Dominant-negative effects of the N-terminal half of prion protein on neurotoxicity of prion protein-like protein/doppel in mice.2008
- Author(s)
  Yoshikawa D, Yamaguchi N, Ishibashi D, Yamanaka H, Okimura N, Yamaguchi Y, Mori T, Miyata H, Shigematsu K, Katamine S, Sakaguchi S.
- Journal Title
  
  J Biol Chem. 283(35)
  
  Pages: 24202-24211
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20500324
[Presentation] マウスにおける微量リチウム持続投与による衝動性の変化の検討2017
- Author(s)
  山口　尚宏
- Organizer
  第36回　リチウム研究会
- Place of Presentation
  日本工業倶楽部会館（東京都千代田区）
- Data Source
  KAKENHI-PROJECT-26461722
[Presentation] マウスにおける低濃度リチウム長期投与による衝動性の変化の検討2015
- Author(s)
  山口尚宏, 黒滝直弘, 小澤寛樹
- Organizer
  第38回日本分子生物学会年会、第88回日本生化学会大会　合同大会
- Place of Presentation
  神戸ポートアイランド（神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26461722
[Presentation] マウスにおける超微量リチウム持続投与による衝動性の変化の検討2014
- Author(s)
  山口　尚宏
- Organizer
  第33回　リチウム研究会
- Place of Presentation
  経団連会館2階　国際会議場（東京都）
- Year and Date
  2014-04-12
- Data Source
  KAKENHI-PROJECT-26461722
[Presentation] マウスにおける低濃度リチウム長期投与による衝動性の変化の検討
- Author(s)
  山口　尚宏
- Organizer
  第36回　日本生物学的精神医学会、第57回日本神経化学会大会　合同年回
- Place of Presentation
  奈良県新公会堂（奈良県）
- Year and Date
  2014-09-28 – 2014-10-01
- Data Source
  KAKENHI-PROJECT-26461722

1. UEZONO YASUHITO (20213340)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 黒滝直弘 (20423634)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results

YAMAGUCHI Naohiro 山口 尚宏

Research Projects

Research Products

Co-Researchers

行動変容を起こす微量リチウム長期経口投与の作用機序解明へのアプローチPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Examination of the impulsivity change of mice administrated the long-term and low-concentrated lithium.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The molecular mechanism of the prion protein and the homolog which cause the neuro-degenerative/-protective function.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Ultrasensitive human prion detection in cerebrospinal fluid by real-time quaking-induced conversion.2011

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Escherichia coli contamination of menstrual blood and effect of bacterial endotoxin on endometriosis.2010

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Human Papillomavirus DNA in Plasma of Patients with HPV16 DNA-positive Uterine Cervical Cancer.2010

Author(s)

Journal Title

NAID

Data Source

[Journal Article] A case of unilateral adrenal hyperplasia being difficult to distinguish from aldosterone-producing adenoma.2009

Author(s)

Journal Title

Data Source

[Journal Article] case of unilateral adrenal hyperplasia being difficult to distinguish from aldosterone-producing adenoma.2009

Author(s)

Journal Title

Data Source

[Journal Article] Analysis of mRNA expression for steroidogenic enzymes in the remaining adrenal cortices attached to adrenocortical adenomas.2008

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Bone marrow stroma cells are susceptible to prion infection.2008

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Dominant-negative effects of the N-terminal half of prion protein on neurotoxicity of prion protein-like protein/doppel in mice.2008

Author(s)

Journal Title

Data Source

[Presentation] マウスにおける微量リチウム持続投与による衝動性の変化の検討2017

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] マウスにおける低濃度リチウム長期投与による衝動性の変化の検討2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] マウスにおける超微量リチウム持続投与による衝動性の変化の検討2014

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] マウスにおける低濃度リチウム長期投与による衝動性の変化の検討

Author(s)

Organizer

Place of Presentation

YAMAGUCHI Naohiro 山口尚宏