NAKAMURA TERUYA 中村照也

… Alternative Names

Nakamura Teruya 中村照也

NAKAMURA Teruya 中村照也

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Researcher Number	40433015
Other IDs
Affiliation (Current)	2025: 熊本大学, 大学院生命科学研究部(薬), 准教授
Affiliation (based on the past Project Information) *help	2021 – 2024: 熊本大学, 大学院生命科学研究部(薬), 准教授 2018 – 2021: 熊本大学, 大学院先導機構, 准教授 2016: 熊本大学, 大学院先導機構, 准教授 2015: 熊本大学, 大学院生命科学研究部, 助教 2011 – 2015: 熊本大学, 生命科学研究部, 助教 … More 2012: 熊本大学, その他の研究科, 助教 2012: 熊本大学, 大学院・生命科学研究部, 助教 2009: Kumamoto University, 大学院・生命科学研究部, 助教 2008: Kumamoto University, 大学院・医学薬学研究部, 助教 Less
Review Section/Research Field	Principal Investigator Physical pharmacy / Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related / Biological Sciences / Basic Section 43020:Structural biochemistry-related / Science and Engineering Except Principal Investigator Basic Section 43030:Functional biochemistry-related
Keywords	Principal Investigator 構造生物学 / DNA修復 / X線結晶構造解析 / DNA複製 / 細胞シグナル伝達 / 中性子結晶構造解析 / 酵素反応 / 蛍光X線ホログラフィー / 蛋白質 / シグナル伝達 … More / 天然変性タンパク質 / エピジェネティクス / Ｘ線結晶構造解析 / 構造活性相関 / 薬物結合蛋白質 / タンパク質複合体 … More Except Principal Investigator 形質膜 / ユビキチン / CFTR / 嚢胞性線維症 / DUB / ユビキチンリガーゼ / ユビキチン化 / タンパク質品質管理 Less

DNA複製におけるゲノム安定性維持機構の構造生物学的研究Principal Investigator
- Principal Investigator
  
  中村照也
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 43020:Structural biochemistry-related
- Research Institution
  Kumamoto University
細菌感染に対する新規自然免疫シグナル伝達の構造生物学的研究Principal Investigator
- Principal Investigator
  
  中村照也
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
- Research Institution
  Kumamoto University
Elucidation and therapeutic application of ubiquitination mechanisms in the PMQC
- Principal Investigator
  
  Okiyoneda Tsukasa
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 43030:Functional biochemistry-related
- Research Institution
  Kwansei Gakuin University
Crystallographic analysis of an anticancer target enzyme at high resolutionPrincipal Investigator
- Principal Investigator
  
  Nakamura Teruya
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
- Research Institution
  Kumamoto University
蛍光Ｘ線ホログラフィーによる酸化ヌクレオチド加水分解酵素の活性サイトの観測Principal Investigator
- Principal Investigator
  
  中村照也
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  Kumamoto University
TRAF6複合体によるシグナル伝達の構造学的解明Principal Investigator
- Principal Investigator
  
  中村照也
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Kumamoto University
Structural study of replication-coupled DNA repairPrincipal Investigator
- Principal Investigator
  
  Nakamura Teruya
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  Kumamoto University
ＤＮＡメチル化制御因子の構造形成を介したヒストン認識及びＤＮＡ脱メチル化保護機構Principal Investigator
- Principal Investigator
  
  中村照也
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Kumamoto University
Structural basis for the drug binding of human alpha1-acid glycoproteinPrincipal Investigator
- Principal Investigator
  
  NAKAMURA Teruya
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  Kumamoto University
Structural basis of the replication-associated DNA repair by the MUTYH-PCNA complexPrincipal Investigator
- Principal Investigator
  
  NAKAMURA Teruya
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  Kumamoto University

[Book] Protein Modifications in Pathogenic Dysregulation of Signaling, Chapter 92015
- Author(s)
  T. Nakamura, Y. Mukai, Y. Tsutsumi, Y. Yamagata
- Total Pages
  15
- Publisher
  Springer
- Data Source
  KAKENHI-PUBLICLY-15H01050
[Book] Protein Modifications in Pathogenic Dysregulation of Signaling, Chapter 92015
- Author(s)
  T. Nakamura, Y. Mukai, Y. Tsutsumi, Y. Yamagata
- Total Pages
  15
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-25460038
[Journal Article] TIFAB regulates the TIFA?TRAF6 signaling pathway involved in innate immunity by forming a heterodimer complex with TIFA2024
- Author(s)
  Nakamura Teruya、Ohyama Chiaki、Sakamoto Madoka、Toma Tsugumasa、Tateishi Hiroshi、Matsuo Mihoko、Chirifu Mami、Ikemizu Shinji、Morioka Hiroshi、Fujita Mikako、Inoue Jun-ichiro、Yamagata Yuriko
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 121 Issue: 11
- DOI
  10.1073/pnas.2318794121
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23KJ1769, KAKENHI-PROJECT-21K06514
[Journal Article] Protonation states of Asp residues in the human Nudix hydrolase MTH1 contribute to its broad substrate recognition2023
- Author(s)
  Nakamura Teruya、Koga‐Ogawa Yukari、Fujimiya Kana、Chirifu Mami、Goto Masataka、Ikemizu Shinji、Nakabeppu Yusaku、Yamagata Yuriko
- Journal Title
  
  FEBS Letters
  
  Volume: in press Issue: 13 Pages: 1770-1778
- DOI
  10.1002/1873-3468.14611
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06514
[Journal Article] Isolation, Synthesis, and Structure?Activity Relationship Study on Daphnane and Tigliane Diterpenes as HIV Latency-Reversing Agents2022
- Author(s)
  El-Desoky Ahmed H. H.、Eguchi Keisuke、Kishimoto Naoki、Asano Toshifumi、Kato Hikaru、Hitora Yuki、Kotani Shunsuke、Nakamura Teruya、Tsuchiya Soken、Kawahara Teppei、Watanabe Masato、Wada Mikiyo、Nakajima Makoto、Watanabe Takashi、Misumi Shogo、Tsukamoto Sachiko
- Journal Title
  
  Journal of Medicinal Chemistry
  
  Volume: 65 Issue: 4 Pages: 3460-3472
- DOI
  10.1021/acs.jmedchem.1c01973
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06997, KAKENHI-PROJECT-20K22710, KAKENHI-PROJECT-20J11188, KAKENHI-PROJECT-21K06514, KAKENHI-PROJECT-21K07055, KAKENHI-PROJECT-23K20310
[Journal Article] Visualization of mutagenic nucleotide processing by Escherichia coli MutT, a Nudix hydrolase2022
- Author(s)
  Nakamura Teruya、Yamagata Yuriko
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 119 Issue: 21
- DOI
  10.1073/pnas.2203118119
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K06514
[Journal Article] RAD18 mediates DNA double-strand break-induced ubiquitination of chromatin protein2021
- Author(s)
  Mustofa Md Kawsar、Tanoue Yuki、Chirifu Mami、Shimasaki Tatsuya、Tateishi Chie、Nakamura Teruya、Tateishi Satoshi
- Journal Title
  
  The Journal of Biochemistry
  
  Volume: in press Issue: 1 Pages: 33-40
- DOI
  10.1093/jb/mvab010
- NAID
  40022722273
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06600, KAKENHI-PROJECT-18K11646, KAKENHI-PROJECT-21K06514
[Journal Article] Molecular recognition of a single-chain Fv antibody specific for GA-pyridine, an advanced glycation end-product (AGE), elucidated using biophysical techniques and synthetic antigen analogues.2021
- Author(s)
  Kobashigawa, Y., Ohara, T., Morita, K., Toyota, Y., Nakamura, T., Kotani. S., Arimori, T., Yamauchi, S., Liu, C., Kitazaki, M., Wakeyama-Miyazaki, Y., Suwa, Y., Uchida-Kamekura, M., Fukuda, N., Sato, T., Nakajima, M., Takagi, J., Yamagata, Y., and Morioka, H
- Journal Title
  
  J. Biochem
  
  Volume: 170 Issue: 3 Pages: 379-387
- DOI
  10.1093/jb/mvab056
- NAID
  40022721879
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06810, KAKENHI-PROJECT-19K06997, KAKENHI-PROJECT-20H00455, KAKENHI-PROJECT-20J11536, KAKENHI-PROJECT-21K06514, KAKENHI-PROJECT-23K20310
[Journal Article] Structure of the mammalian adenine DNA glycosylase MUTYH: insights into the base excision repair pathway and cancer2021
- Author(s)
  Nakamura Teruya、Okabe Kohtaro、Hirayama Shogo、Chirifu Mami、Ikemizu Shinji、Morioka Hiroshi、Nakabeppu Yusaku、Yamagata Yuriko
- Journal Title
  
  Nucleic Acids Research
  
  Volume: 49 Issue: 12 Pages: 7154-7163
- DOI
  10.1093/nar/gkab492
- NAID
  120007119905
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06514
[Journal Article] A mannosylated ,PEGylated albumin as a drug delivery system for the treatment of cancer stroma cells.2021
- Author(s)
  Mizuta Y, Maeda H, Ishima T, Minayoshi Y, Ichimizu S, Kinoshita R, Fujita I, Kai T, Hirata H, Nakamura T, Saruwari J, Arima H, Watanabe H, Otagiri M, Maruyama T
- Journal Title
  
  Adv Funct Mater
  
  Volume: 31 Issue: 43 Pages: 2104136-2104136
- DOI
  10.1002/adfm.202104136
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06810, KAKENHI-PROJECT-19J23629, KAKENHI-PROJECT-21K06514, KAKENHI-PROJECT-21K15315
[Journal Article] A Conformational Escape Reaction of HIV-1 against an Allosteric Integrase Inhibitor2020
- Author(s)
  Nakamura Tomofumi、Nakamura Teruya、Amano Masayuki、Miyakawa Toshikazu、Yamagata Yuriko、Matsuoka Masao、Nakata Hirotomo
- Journal Title
  
  Journal of Virology
  
  Volume: 94 Issue: 19 Pages: 1-20
- DOI
  10.1128/jvi.00486-20
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06600, KAKENHI-PROJECT-18K08435, KAKENHI-PROJECT-18K08436, KAKENHI-PROJECT-18K16180
[Journal Article] Structural analysis of TIFA: Insight into TIFA-dependent signal transduction in innate immunity2020
- Author(s)
  Nakamura Teruya、Hashikawa Chie、Okabe Kohtaro、Yokote Yuya、Chirifu Mami、Toma-Fukai Sachiko、Nakamura Narushi、Matsuo Mihoko、Kamikariya Miho、Okamoto Yoshinari、Gohda Jin、Akiyama Taishin、Semba Kentaro、Ikemizu Shinji、Otsuka Masami、Inoue Jun-ichiro、Yamagata Yuriko
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 5152-5152
- DOI
  10.1038/s41598-020-61972-6
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06600, KAKENHI-PLANNED-16H06575, KAKENHI-INTERNATIONAL-16K21739, KAKENHI-ORGANIZER-16H06573, KAKENHI-PROJECT-20H03441, KAKENHI-PROJECT-17H03999
[Journal Article] Lactose-appended β-cyclodextrin as an effective nanocarrier for brain delivery2020
- Author(s)
  Yokoyama Ryoma、Taharabaru Toru、Nishida Takumi、Ohno Yoshitaka、Maeda Yuki、Sato Masahiro、Ishikura Kandai、Yanagihara Kazunori、Takagi Hiroki、Nakamura Teruya、Ito Shingo、Ohtsuki Sumio、Arima Hidetoshi、Onodera Risako、Higashi Taishi、Motoyama Keiichi
- Journal Title
  
  Journal of Controlled Release
  
  Volume: 328 Pages: 722-735
- DOI
  10.1016/j.jconrel.2020.09.043
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06600
[Journal Article] X-ray Structure Analysis of Human Oxidized Nucleotide Hydrolase MTH1 using Crystals Obtained under Microgravity2019
- Author(s)
  Nakamura T, Hirata K, Fujimiya K, Chirifu M, Arimori T, Tamada T, Ikemizu S, Yamagata Y
- Journal Title
  
  International journal of microgravity science and application
  
  Volume: 36 Issue: 1 Pages: 360103
- DOI
  10.15011//jasma.36.360103
- NAID
  130007769928
- ISSN
  2188-9783
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06600, KAKENHI-PROJECT-16K07276, KAKENHI-PROJECT-18H02389
[Journal Article] Anammox Organism KSU-1 Expresses a Novel His/DOPA Ligated Cytochrome c2018
- Author(s)
  Hira Daisuke、Kitamura Ryuji、Nakamura Teruya、Yamagata Yuriko、Furukawa Kenji、Fujii Takao
- Journal Title
  
  Journal of Molecular Biology
  
  Volume: 430 Issue: 8 Pages: 1189-1200
- DOI
  10.1016/j.jmb.2018.02.017
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06600, KAKENHI-PROJECT-16K07703
[Journal Article] Structural and Kinetic Studies of the Human Nudix Hydrolase MTH1 Reveal the Mechanism for Its Broad Substrate Specificity.2017
- Author(s)
  Waz S, Nakamura T, Hirata K, Koga-Ogawa Y, Chirifu M, Arimori T, Tamada T, Ikemizu S, Nakabeppu Y, Yamagata Y.
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 292 Issue: 7 Pages: 2785-2794
- DOI
  10.1074/jbc.m116.749713
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-15H01050
[Journal Article] Reaction Mechanisms of Nucleic Acid Enzymes, Oxidative Nucleotide Hydrolase MutT and Translesion DNA Polymerase η2014
- Author(s)
  中村照也
- Journal Title
  
  Nihon Kessho Gakkaishi
  
  Volume: 56 Issue: 2 Pages: 123-128
- DOI
  10.5940/jcrsj.56.123
- NAID
  130004552884
- ISSN
  0369-4585, 1884-5576
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-25117722, KAKENHI-PROJECT-25460038
[Journal Article] 時分割タンパク質結晶学によるDNAポリメラーゼηのヌクレオチド転移反応の可視化2013
- Author(s)
  中村照也
- Journal Title
  
  日本結晶学会誌
  
  Volume: 55 Pages: 42-46
- NAID
  10031156005
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-24113719
[Journal Article] Crystallization and preliminary X-ray analysis of human MTH1 with a homogeneous N-terminus.2013
- Author(s)
  Koga Y, Inazato M, Nakamura T, Hashikawa C, Chirifu M, Michi A, Yamashita T, Toma S, Kuniyasu A, Ikemizu S, Nakabeppu Y, Yamagata Y.
- Journal Title
  
  Acta Crystallogr Sect F Struct Biol Cryst Commun
  
  Volume: 69(Pt 1) Issue: 1 Pages: 45-48
- DOI
  10.1107/s1744309112048002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22221004, KAKENHI-PROJECT-23390027, KAKENHI-PROJECT-23659025, KAKENHI-PROJECT-23790052, KAKENHI-PROJECT-25440031, KAKENHI-PLANNED-22131007, KAKENHI-PUBLICLY-23121523, KAKENHI-PUBLICLY-24113719
[Journal Article] Mechanism of the nucleotidyl-transfer reaction in DNA polymerase revealed by time-resolved protein crystallography2013
- Author(s)
  Nakamura T., Zhao Y., Yamagata Y., Hua Y.J., Yang W.
- Journal Title
  
  Biophysics
  
  Volume: 9 Pages: 31-36
- NAID
  130003366027
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460038
[Journal Article] 時分割タンパク質結晶学による DNA ポリメラーゼnのヌクレオチド転移反応の可視化2013
- Author(s)
  中村照也,山縣ゆり子,Wei Yang
- Journal Title
  
  日本結晶学会誌
  
  Volume: 55 Pages: 42-46
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790052
[Journal Article] 時分割タンパク質結晶学によるDNAポリメラーゼηのヌクレオチド転移反応の可視化2013
- Author(s)
  中村照也
- Journal Title
  
  日本結晶学会誌
  
  Volume: 55 Pages: 42-46
- NAID
  10031156005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790052
[Journal Article] DNAポリメラーゼηによるリン酸ジエステル結合の形成過程の観察2013
- Author(s)
  中村照也，山縣ゆり子，Wei Yang
- Journal Title
  
  生物物理
  
  Volume: 53 Pages: 254-257
- NAID
  10031191847
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460038
[Journal Article] DNAポリメラーゼηによるリン酸ジエステル結合の形成過程の観察2013
- Author(s)
  中村照也
- Journal Title
  
  生物物理
  
  Volume: 53 Pages: 254-257
- NAID
  10031191847
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-25117722
[Journal Article] DNAポリメラーゼηによるリン酸ジエステル結合の形成過程の観察2013
- Author(s)
  中村照也
- Journal Title
  
  生物物理
  
  Volume: 53 Pages: 254-257
- NAID
  10031191847
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-24113719
[Journal Article] Mechanism of the nucleotidyl-transfer reaction in DNA polymerase revealed by time-resolved protein crystallography2013
- Author(s)
  Nakamura T.
- Journal Title
  
  Biophysics
  
  Volume: 9 Pages: 31-36
- NAID
  130003366027
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-25117722
[Journal Article] Mechanism of the nucleotidyl-transfer reaction in DNA polymerase revealed by time-resolved protein crystallography2013
- Author(s)
  Nakamura T.
- Journal Title
  
  Biophysics
  
  Volume: 9 Pages: 31-36
- NAID
  130003366027
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-24113719
[Journal Article] Watching DNA polymerase η make a phosphodiester bond.2012
- Author(s)
  Nakamura T.
- Journal Title
  
  Nature
  
  Volume: 487 Issue: 7406 Pages: 196-201
- DOI
  10.1038/nature11181
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790052, KAKENHI-PLANNED-22131007, KAKENHI-PUBLICLY-24113719
[Journal Article] Structural Insights into Differences in Drug-binding Selectivity between Two Forms of Human α1-Acid Glycoprotein Genetic Variants, the A and F1^*S Forms2011
- Author(s)
  K.Nishi, et al
- Journal Title
  
  J.Biol.Chem
  
  Volume: 286 Issue: 16 Pages: 14427-14434
- DOI
  10.1074/jbc.m110.208926
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390008, KAKENHI-PROJECT-23790052
[Journal Article] Diverse Substrate Recognition and Hydrolysis Mechanisms of Human NUDT52011
- Author(s)
  Takao Arimori, at al
- Journal Title
  
  Nucleic Acids Res.
  
  Volume: 39 Issue: 20 Pages: 8972-8983
- DOI
  10.1093/nar/gkr575
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22131007, KAKENHI-PROJECT-22370003, KAKENHI-PROJECT-22570007, KAKENHI-PUBLICLY-23121523, KAKENHI-PROJECT-23790052
[Journal Article] Structural and dynamic features of the MutT protein in the recognition of nucleotides with the mutagenic 8-oxoguanine base2010
- Author(s)
  Teruya Nakamura
- Journal Title
  
  J.Biol.Chem. 285
  
  Pages: 444-452
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790040
[Journal Article] Role of the glutamic acid 54 residue in transthyretin stability and thyroxine binding2010
- Author(s)
  Masanori Miyata, Takashi Sato, Mineyuki Mizuguchi, Teruya Nakamura, Shinji Ikemizu, Yuko Nabeshima, Seiko Susuki, Yoshiaki Suwa, Hiroshi Morioka, Yukio Ando, Mary Ann Suico, Tsuyoshi Shuto, Tomoaki Koga, Yuriko Yamagata, Hirofumi Kai
- Journal Title
  
  Biochemistry 49
  
  Pages: 114-123
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790040
[Journal Article] Structural and dynamic features of the MutT protein in the recognition of nucleotides with the mutagenic 8-oxoguanine base2010
- Author(s)
  Teruya Nakamura, Sachiko Meshitsuka, Seiju Kitagawa, Nanase Abe, Junichi Yamada, Tetsuya Ishino, Hiroaki Nakano, Teruhisa Tsuzuki, Takefumi Doi, Yuji Kobayashi, Satoshi Fujii, Mutsuo Sekiguchi, Yuriko Yamagata
- Journal Title
  
  J. Biol. Chem. 285
  
  Pages: 444-452
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790040
[Journal Article] Fast binding kinetics and conserved 3D structure underlie the antagonistic activity of mutant TNF: useful information for designing artificial proteo-antagonists2009
- Author(s)
  Yohei Mukai, Teruya Nakamura, Yasuo Yoshioka, Hiroko Shibata, Yasuhiro Abe, Tetsuya Nomura, Madoka Taniai, Tsunetaka Ohta, Shinsaku Nakagawa, Shin-ichi Tsunoda, Haruhiko Kamada, Yuriko Yamagata, Yasuo Tsutsumi
- Journal Title
  
  J. Biochem. 146
  
  Pages: 167-172
- NAID
  10026302534
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790040
[Journal Article] Structure-function relationship of tumor necrosis factor (TNF) and its receptor interaction based on 3D structural analysis of a fully active TNFR1-selective TNF mutant2009
- Author(s)
  Yohei Mukai, Hiroko Shibata, Teruya Nakamura, Yasuo Yoshioka, Yasuhiro Abe, Tetsuya Nomura, Madoka Taniai, Tsunetaka Ohta, Shinji Ikemizu, Shinsaku Nakagawa, Shin-ichi Tsunoda, Haruhiko Kamada, Yuriko Yamagata, Yasuo Tsutsumi
- Journal Title
  
  J. Mol. Biol. 385
  
  Pages: 1221-1229
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790040
[Journal Article] Crystallization and preliminary X-ray analysis of the tumour necrosis factor alpha-tumour necrosis factor receptor type 2 complex2009
- Author(s)
  Yohei Mukai, Teruya Nakamura, Yasuo Yoshioka, Shin-ichi Tsunoda, Haruhiko Kamada, Shinsaku Nakagawa, Yuriko Yamagata, Yasuo Tsutsumi
- Journal Title
  
  Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 65
  
  Pages: 295-298
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790040
[Presentation] ヒト酸化ヌクレオチド加水分解酵素の活性部位のプロトン化状態と幅広い基質特異性の関係2024
- Author(s)
  小川由香里, 藤宮佳菜, 池鯉鮒麻美, 後藤大空, 池水信二, 中別府雄作, 山縣ゆり子, 中村照也
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-21K06514
[Presentation] ヒト酸化ヌクレオチド加水分解酵素による酸化dNTPおよび酸化rNTP認識の構造学的基盤2023
- Author(s)
  興梠利彦, 藤宮佳菜, 平田啓介, 池鯉鮒麻美, 池水信二, 山縣ゆり子, 中村照也
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-21K06514
[Presentation] ヒトMTH1の幅広い基質認識におけるAsp残基のプロトン化状態2023
- Author(s)
  小川由香里, 藤宮佳菜, 池鯉鮒麻美, 後藤大空, 池水信二, 中別府雄作, 山縣ゆり子, 中村照也
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-21K06514
[Presentation] ヒト酸化ヌクレオチド加水分解酵素によるヌクレオチド結合の構造学的研究2022
- Author(s)
  興梠利彦, 藤宮佳菜, 平田啓介, 池鯉鮒麻美, 池水信二, 山縣ゆり子, 中村照也
- Organizer
  フォーラム2022：衛生薬学・環境トキシコロジー
- Data Source
  KAKENHI-PROJECT-21K06514
[Presentation] Time-resolved X-ray crystallography of E. coli MutT, a Nudix hydrolase2022
- Author(s)
  中村照也, 山縣ゆり子
- Organizer
  第60回日本生物物理学会年会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06514
[Presentation] TIFAを介した自然免疫シグナル伝達機構の構造生物学的研究2022
- Author(s)
  中村照也
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-21K06514
[Presentation] 酵素反応機構の精密解析を目指して2022
- Author(s)
  中村照也
- Organizer
  第95回日本生化学大会
- Invited
- Data Source
  KAKENHI-PROJECT-21K06514
[Presentation] DNAの酸化損傷の回避・修復機構の構造学的研究2022
- Author(s)
  中村照也
- Organizer
  第81回SPring-8 先端利用技術ワークショップ / 大阪大学蛋白質研究所セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-21K06514
[Presentation] X線・中性子構造解析を用いた酵素反応機構の研究2021
- Author(s)
  中村照也
- Organizer
  第94回日本生化学大会
- Invited
- Data Source
  KAKENHI-PROJECT-21K06514
[Presentation] タンパク質-リガンド間相互作用を水素原子レベルで視る2021
- Author(s)
  中村照也
- Organizer
  理化学研究所・熊本大学合同生命科学領域DXシンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-21K06514
[Presentation] 哺乳類由来アデニンDNAグリコシラーゼMUTYHのX線結晶構造2021
- Author(s)
  中村照也
- Organizer
  日本結晶学会令和3年度年会
- Data Source
  KAKENHI-PROJECT-21K06514
[Presentation] 酵素の基質特異性に関わる水素原子の観察2020
- Author(s)
  中村照也
- Organizer
  CBI学会 2020年大会
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06600
[Presentation] 自然免疫に関わるシグナル分子TIFAの構造学的研究2020
- Author(s)
  中村照也
- Organizer
  日本結晶学会令和2年度年会
- Data Source
  KAKENHI-PROJECT-18K06600
[Presentation] ヒト酸化ヌクレオチド加水分解酵素の新規基質の同定2019
- Author(s)
  藤宮　佳菜、中村　照也、平田　啓介、池鯉鮒　麻美、池水　信二、山縣　ゆり子
- Organizer
  第43回蛋白質と酵素の構造と機能に関する九州シンポジウム
- Data Source
  KAKENHI-PROJECT-18K06600
[Presentation] 酵素の精密構造解析抗がん剤標的分子の基質認識における水素原子の役割2019
- Author(s)
  中村　照也
- Organizer
  日本プロテオーム学会 2019年大会・第70回日本電気泳動学会
- Invited
- Data Source
  KAKENHI-PROJECT-18K06600
[Presentation] ゲノム安定性維持機構の構造生物学2019
- Author(s)
  中村　照也
- Organizer
  第2回熊本大学ライフサイエンスシーズ探索研究会
- Invited
- Data Source
  KAKENHI-PROJECT-18K06600
[Presentation] ヒト酸化ヌクレオチド加水分解酵素の構造学的研究-水素原子レベルでの酵素反応機構の解明を目指して-2018
- Author(s)
  中村　照也
- Organizer
  平成30年度iBIX-JAXA-KEK物構研-QST合同タンパク質研究会
- Invited
- Data Source
  KAKENHI-PROJECT-18K06600
[Presentation] Crystal structure of human oxidative nucleotide hydrolase in complex with a newly found substrate2018
- Author(s)
  Teruya Nakamura
- Organizer
  第56回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-18K06600
[Presentation] 時分割X 線結晶構造解析による酸化ヌクレオチド加水分解酵素の反応機構の解明2016
- Author(s)
  平田啓介、中村照也、吉川紘平、池鯉鮒麻美、池水信二、山縣ゆり子
- Organizer
  量子ビームサイエンスフェスタ第７回 MLF シンポジウム／第 33 回 PF シンポジウム
- Place of Presentation
  つくば
- Year and Date
  2016-03-15
- Data Source
  KAKENHI-PROJECT-25460038
[Presentation] Structural and kinetic analysis of the broad substrate specificity of human oxidative nucleotide hydrolase2016
- Author(s)
  Waz S, Nakamura T, Hirata K, Chirifu M, Ikemizu S, Yamagata Y.
- Organizer
  第16回日本蛋白質科学会年会
- Place of Presentation
  福岡
- Year and Date
  2016-06-07
- Data Source
  KAKENHI-PUBLICLY-15H01050
[Presentation] 低温トラップ法を用いた酸化ヌクレオチド加水分解酵素の時分割X線結晶構造解析2016
- Author(s)
  平田啓介，中村照也，池鯉鮒麻美，池水信二，山縣ゆり子
- Organizer
  第14回次世代を担う若手のためのフィジカル・ファーマフォーラム (PPF2016)
- Place of Presentation
  大阪
- Year and Date
  2016-08-27
- Data Source
  KAKENHI-PUBLICLY-15H01050
[Presentation] Structural study on human oxidative hydrolase using high-quality crystals2016
- Author(s)
  Nakamura T
- Organizer
  The 2nd International Symposium Space Science of High Quality Protein Crystallization Technology
- Place of Presentation
  Tokyo
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01050
[Presentation] 時分割X 線結晶構造解析による酸化ヌクレオチド加水分解酵素の反応機構の解明2016
- Author(s)
  平田啓介、中村照也、吉川紘平、池鯉鮒麻美、池水信二、山縣ゆり子
- Organizer
  量子ビームサイエンスフェスタ第７回 MLF シンポジウム／第 33 回 PF シンポジウム
- Place of Presentation
  つくば
- Year and Date
  2016-03-15
- Data Source
  KAKENHI-PUBLICLY-15H01050
[Presentation] Unique mechanism for broad substrate specificity of human MTH12016
- Author(s)
  Waz S, Nakamura T, Hirata K, Chirifu M, Ikemizu S, Yamagata Y.
- Organizer
  第54回生物物理学会年会
- Place of Presentation
  つくば
- Year and Date
  2016-11-25
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01050
[Presentation] 酵素反応を原子レベルで観察する2015
- Author(s)
  中村照也
- Organizer
  宮崎大学　テニュアトラック推進機構主催セミナー「蛋白質立体構造解析の最前線」
- Place of Presentation
  宮崎大学
- Year and Date
  2015-03-23
- Invited
- Data Source
  KAKENHI-PUBLICLY-25117722
[Presentation] High resolution X-ray diffraction study of an enzyme for oxidative nucleotide processing2015
- Author(s)
  Keisuke Hirata, Teruya Nakamura, Mami Chirifu, Shinji Ikemizu, Yuriko Yamagata
- Organizer
  The 53rd Annual Meeting of the Biophysical Society of Japan
- Place of Presentation
  金沢
- Year and Date
  2015-09-13
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01050
[Presentation] High resolution X-ray diffraction study of an enzyme for oxidative nucleotide processing2015
- Author(s)
  Keisuke Hirata, Teruya Nakamura, Mami Chirifu, Shinji Ikemizu, Yuriko Yamagata
- Organizer
  The 53rd Annual Meeting of the Biophysical Society of Japan
- Place of Presentation
  金沢
- Year and Date
  2015-09-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460038
[Presentation] 酵素反応を原子レベルで観察する2015
- Author(s)
  中村照也
- Organizer
  宮崎大学　テニュアトラック推進機構主催セミナー「蛋白質立体構造解析の最前線」
- Place of Presentation
  宮崎大学
- Year and Date
  2015-03-23
- Invited
- Data Source
  KAKENHI-PROJECT-25460038
[Presentation] 金属イオンを介した酸化ヌクレオチド加水分解酵素の反応機構2015
- Author(s)
  中村照也，山縣ゆり子
- Organizer
  3D活性サイト科学　春の学校
- Place of Presentation
  奈良
- Year and Date
  2015-05-30
- Data Source
  KAKENHI-PUBLICLY-15H01050
[Presentation] DNA ポリメラーゼによるヌクレオチド転移反応の可視化2013
- Author(s)
  中村照也
- Organizer
  日本薬学会第133 年会
- Place of Presentation
  パシフィコ横浜(横浜)
- Year and Date
  2013-03-29
- Data Source
  KAKENHI-PROJECT-23790052
[Presentation] Expression and purification for protein crystallography of a DNA methylation regulatory protein2013
- Author(s)
  Nakamura T.
- Organizer
  The 2nd International Symposium on Intrinsically Disordered Proteins
- Place of Presentation
  理化学研究所　横浜研究所
- Year and Date
  2013-01-23
- Data Source
  KAKENHI-PUBLICLY-24113719
[Presentation] 時分割X線結晶構造解析によるDNAポリメラーゼηのヌクレオチド転移反応過程の追跡2013
- Author(s)
  中村照也
- Organizer
  回折構造生物第169委員会　第42回研究会
- Place of Presentation
  ゆうぽうと，東京
- Invited
- Data Source
  KAKENHI-PROJECT-23790052
[Presentation] 時分割 X 線結晶構造解析による DNA ポリメラーゼnのヌクレオチド転移反応過程の追跡2013
- Author(s)
  中村照也
- Organizer
  回折構造生物第169 委員会第42回研究会
- Place of Presentation
  ゆうぽうと(東京)
- Year and Date
  2013-02-21
- Data Source
  KAKENHI-PROJECT-23790052
[Presentation] DNA損傷修復に働く酸化ヌクレオチド分解酵素MutTとDNAポリメラーゼηの反応機構の解明2013
- Author(s)
  中村照也
- Organizer
  平成25年度日本結晶学会年会，進歩賞受賞講演
- Place of Presentation
  熊本大学
- Invited
- Data Source
  KAKENHI-PUBLICLY-24113719
[Presentation] DNA損傷修復に働く酸化ヌクレオチド分解酵素MutTとDNAポリメラーゼηの反応機構の解明2013
- Author(s)
  中村照也
- Organizer
  平成25年度日本結晶学会年会，進歩賞受賞講演
- Place of Presentation
  熊本大学
- Invited
- Data Source
  KAKENHI-PROJECT-25460038
[Presentation] DNA損傷修復に働く酸化ヌクレオチド分解酵素MutTとDNAポリメラーゼηの反応機構の解明2013
- Author(s)
  中村照也
- Organizer
  平成25年度日本結晶学会年会，進歩賞受賞講演
- Place of Presentation
  熊本大学
- Invited
- Data Source
  KAKENHI-PUBLICLY-25117722
[Presentation] Visualization ofoxidized nucleotide processing by E. coliMutT2012
- Author(s)
  Teruya Nakamura
- Organizer
  Zing conferences, Nucleic AcidsConference 2012
- Place of Presentation
  TheOccidental Grand Xcaret (Mexico)
- Year and Date
  2012-11-17
- Data Source
  KAKENHI-PROJECT-23790052
[Presentation] ヒト DNA polymerase・nによるヌクレオチド転移反応機構の解明2012
- Author(s)
  中村照也
- Organizer
  遺伝研研究集会「遺伝情報の安定性を支える分子メカニズム」
- Place of Presentation
  国立遺伝学研究所(三島)
- Year and Date
  2012-10-03
- Data Source
  KAKENHI-PROJECT-23790052
[Presentation] MutT による 8-oxo-dGTP 加水分解反応機構の解明2012
- Author(s)
  中村照也
- Organizer
  第29回日本薬学会九州支部大会
- Place of Presentation
  熊本大学薬学部 (熊本)
- Year and Date
  2012-12-08
- Data Source
  KAKENHI-PROJECT-23790052
[Presentation] Watching DNA polymerase η make a phosphodiester bond2012
- Author(s)
  Nakamura T.
- Organizer
  第50回日本生物物理学会年会
- Place of Presentation
  名古屋大学
- Year and Date
  2012-09-22
- Invited
- Data Source
  KAKENHI-PUBLICLY-24113719
[Presentation] ヒトa1-酸性糖タンパク質による薬物結合の構造学的基盤2012
- Author(s)
  中村照也
- Organizer
  第12回日本蛋白質科学会年会
- Place of Presentation
  名古屋国際会議場(名古屋)
- Year and Date
  2012-06-21
- Data Source
  KAKENHI-PROJECT-23790052
[Presentation] ヒトDNA polymerase ηによるヌクレオチド転移反応機構の解明2012
- Author(s)
  中村照也
- Organizer
  遺伝研研究集会　「遺伝情報の安定性を支える分子メカニズム」
- Place of Presentation
  国立遺伝学研究所
- Year and Date
  2012-10-03
- Invited
- Data Source
  KAKENHI-PUBLICLY-24113719
[Presentation] Visualization ofreaction processes by nucleic acidsenzymes2012
- Author(s)
  Teruya Nakamura
- Organizer
  DNA Repair Mini-Symposium Featuring Eminent Japanese Scientists atNIH
- Place of Presentation
  National Institutes ofHealth (USA)
- Year and Date
  2012-04-10
- Data Source
  KAKENHI-PROJECT-23790052
[Presentation] DNA ポリメラーゼnによるヌクレオチド転移反応の時分割X結晶構造解析2012
- Author(s)
  中村照也
- Organizer
  平成 24 年度日本結晶学会年会
- Place of Presentation
  東北大学(仙台)
- Year and Date
  2012-10-25
- Data Source
  KAKENHI-PROJECT-23790052
[Presentation] ヒトalpha1-酸性糖タンパク質による薬物結合の構造学的基盤2012
- Author(s)
  中村照也
- Organizer
  第12回日本蛋白質科学会年会
- Place of Presentation
  名古屋国際会議場
- Data Source
  KAKENHI-PROJECT-23790052
[Presentation] Watching DNA polymerase n make a phosphodiester bond2012
- Author(s)
  Teruya Nakamura
- Organizer
  第50回日本生物物理学会年会
- Place of Presentation
  名古屋大学(名古屋)
- Year and Date
  2012-09-23
- Data Source
  KAKENHI-PROJECT-23790052
[Presentation] Visualization of reaction processes by nucleic acids enzymes2012
- Author(s)
  Teruya Nakamura
- Organizer
  DNA Repair Mini-Symposium Featuring Eminent Japanese Scientists at NIH
- Place of Presentation
  NIH, USA
- Invited
- Data Source
  KAKENHI-PROJECT-23790052
[Presentation] ヒトMTH1の酸化ヌクレオチドに対する幅広い基質特異性の構造学的基盤2009
- Author(s)
  中村照也
- Organizer
  第26回PFシンポジウム
- Place of Presentation
  つくば国際会議場, つくば
- Year and Date
  2009-03-25
- Data Source
  KAKENHI-PROJECT-20790040
[Presentation] Visualization of the Mn2+ dependent 8-oxo-dGTP hydrolysis reaction in E. coli MutT crystal2009
- Author(s)
  Teruya Nakamura
- Organizer
  第19回金属の関与する生体関連反応シンポジウム
- Place of Presentation
  大阪大学銀杏会館, 大阪
- Year and Date
  2009-06-12
- Data Source
  KAKENHI-PROJECT-20790040
[Presentation] 機能未知であるヒト一回膜貫通型タンパク質のC末ドメインの立体構造に基づく機能予測2009
- Author(s)
  中村照也
- Organizer
  第9回日本蛋白質科学会年会
- Place of Presentation
  熊本全日空ホテルニュースカイ, 熊本
- Year and Date
  2009-05-20
- Data Source
  KAKENHI-PROJECT-20790040
[Presentation] Visualization of the Mn^<2+> dependent 8-oxo-dGTP hydrolysis reaction in E.coli MutT crystal2009
- Author(s)
  中村照也
- Organizer
  第19回金属の関与する生体関連反応シンポジウム
- Place of Presentation
  大阪大学銀杏会館
- Year and Date
  2009-06-12
- Data Source
  KAKENHI-PROJECT-20790040
[Presentation] 動的タンパク質結晶学により捕らえた8-oxo-dGTPaseの求核水分子の活性化機構2009
- Author(s)
  中村照也
- Organizer
  特定領域研究「生体超分子の構造形成と機能制御の原子機構」, 第6回公開シンポジウム
- Place of Presentation
  千里ライフサイエンスセンター, 大阪
- Year and Date
  2009-12-02
- Data Source
  KAKENHI-PROJECT-20790040
[Presentation] 動的蛋白質結晶学により捕らえた8-oxo-dGTPaseの求核水分子の活性化機構2009
- Author(s)
  中村照也
- Organizer
  特定領域研究「生体超分子の構造形成と機能制御の原子機構」第6回公開シンポジウム
- Place of Presentation
  千里ライフサイエンスセンター
- Year and Date
  2009-12-02
- Data Source
  KAKENHI-PROJECT-20790040
[Presentation] High-resolution X-ray diffraction study of the hMTH1 mutant2008
- Author(s)
  中村照也
- Organizer
  XXI Congress and General Assembly of the International Union of Crystallography(IUCr2008)
- Place of Presentation
  大阪国際会議場(グランキューブ大阪)
- Data Source
  KAKENHI-PROJECT-20790040
[Presentation] High-resolution X-ray diffraction study of the hMTH1 mutant2008
- Author(s)
  Teruya Nakamura
- Organizer
  XXI Congress and General Assembly of the International Union of Crystallography (IUCr2008)
- Place of Presentation
  大阪国際会議場, 大阪
- Data Source
  KAKENHI-PROJECT-20790040
[Presentation] Structural study on the TNF and TNFR2 complex
- Author(s)
  Teruya Nakamura, Yohei Mukai, Yasuo Yoshioka, Shin-ichi Tsunoda, Yuriko Yamagata, Yasuo Tsutsumi
- Organizer
  2nd International Symposium on Protein Modifications in Pathogenic Dysregulation of Signaling
- Place of Presentation
  東京大学医科学研究所
- Year and Date
  2015-01-23 – 2015-01-24
- Data Source
  KAKENHI-PUBLICLY-25117722
[Presentation] TRAFのシグナル伝達分子のＸ線結晶構造
- Author(s)
  中村照也, 橋川智恵, 上仮屋美歩，野崎真里香，池鯉鮒麻美，藤間祥子, 田口祐，合田仁，秋山泰身，仙波憲太郎，岡本良成，池水信二，大塚雅巳，井上純一郎, 山縣ゆり子
- Organizer
  平成26年度日本結晶学会年会
- Place of Presentation
  東京大学
- Year and Date
  2014-11-01 – 2014-11-03
- Data Source
  KAKENHI-PUBLICLY-25117722

1. Okiyoneda Tsukasa (90398248)

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2. 高橋宏隆 (70432804)

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3. 石黒洋 (90303651)

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4. 福田亮介 (90825308)

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5. 立石智 (00227109)

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6. KOTANI Shunsuke

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7. 中別府雄作

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8. 森岡弘志

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9. 小田切優樹

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NAKAMURA TERUYA 中村 照也

Nakamura Teruya 中村 照也

NAKAMURA Teruya 中村 照也

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DNA複製におけるゲノム安定性維持機構の構造生物学的研究Principal Investigator

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細菌感染に対する新規自然免疫シグナル伝達の構造生物学的研究Principal Investigator

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Elucidation and therapeutic application of ubiquitination mechanisms in the PMQC

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Crystallographic analysis of an anticancer target enzyme at high resolutionPrincipal Investigator

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蛍光Ｘ線ホログラフィーによる酸化ヌクレオチド加水分解酵素の活性サイトの観測Principal Investigator

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TRAF6複合体によるシグナル伝達の構造学的解明Principal Investigator

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Structural study of replication-coupled DNA repairPrincipal Investigator

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ＤＮＡメチル化制御因子の構造形成を介したヒストン認識及びＤＮＡ脱メチル化保護機構Principal Investigator

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Structural basis for the drug binding of human alpha1-acid glycoproteinPrincipal Investigator

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Structural basis of the replication-associated DNA repair by the MUTYH-PCNA complexPrincipal Investigator

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[Book] Protein Modifications in Pathogenic Dysregulation of Signaling, Chapter 92015

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[Book] Protein Modifications in Pathogenic Dysregulation of Signaling, Chapter 92015

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[Journal Article] TIFAB regulates the TIFA?TRAF6 signaling pathway involved in innate immunity by forming a heterodimer complex with TIFA2024

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NAKAMURA TERUYA 中村照也

Nakamura Teruya 中村照也

NAKAMURA Teruya 中村照也