Hibino Kayo 日比野佳代

… Alternative Names

HIBINO Kayo 日比野佳代

日比野佳代ヒビノカヨ

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Researcher Number	40435673
Other IDs
External Links
Affiliation (Current)	2025: 大阪大学, 蛋白質研究所, 特任研究員(常勤)
Affiliation (based on the past Project Information) *help	2020 – 2024: 国立遺伝学研究所, 遺伝メカニズム研究系, 助教 2017 – 2018: 国立遺伝学研究所, 構造遺伝学研究センター, 助教 2016: 国立遺伝学研究所, 大学共同利用機関等の部局等, 助教 2015: 国立遺伝学研究所, 構造遺伝学研究センター, 助教 2013 – 2014: 独立行政法人理化学研究所, 生命システム研究センター, 研究員 … More 2012: 独立行政法人理化学研究所, 細胞シグナル動態研究グループ, 研究員 2010: 独立行政法人理化学研究所, 佐甲細胞情報研究室, 研究員 2006 – 2007: 独立行政法人理化学研究所, 佐甲細胞情報研究室, 協力研究員 Less
Review Section/Research Field	Principal Investigator Basic Section 43040:Biophysics-related / Biophysics / Living organism molecular science Except Principal Investigator Transformative Research Areas, Section (III) / Biophysics / Nanomaterials/Nanobioscience
Keywords	Principal Investigator 1分子生物学 / 生物物理学 / ゲノム / １分子イメージング / 単一ヌクレオソームイメージング / ヌクレオソーム / クロマチン動態 / 超解像顕微鏡法 / 1分子イメージング / RNA転写 … More / ゲノムDNA / 1分子FRET / 細胞内1分子解析 / 蛍光プローブ / 蛍光スペクトル計測 / ライブセルイメージング / 細胞動態計測 / FRET / 1細胞計測 / 細胞内1分子計測 / 細胞操作 / 細胞状態 / RAF / 細胞内情報処理機構 / 細胞内情報伝達反応 / Raf / Ras / 緑色蛍光蛋白質 / 分子内構造変化 / スレオニンキナーゼ / セリン / 細胞内情報伝達 / 1分子可視化解析 / 生物物理 … More Except Principal Investigator PIポリアミド / AFM / 超解像イメージング / ゲノミクス解析 / 原子間力顕微鏡 / ゲノミックス解析 / 超解像顕微鏡 / クロマチン / ヌクレオソーム / 細胞情報・動態 / 分子構造変化ダイナミクス / 高時間分解計測 / 統計的データ解析 / FRET / 単一分子計測 / EGFR Less

Single molecule & super resolution imaging of chromatin networking through transcription hubs.Principal Investigator
- Principal Investigator
  
  Hibino Kayo
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43040:Biophysics-related
- Research Institution
  National Institute of Genetics
Modality of nucleosome dynamics
- Principal Investigator
  
  前島一博
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  National Institute of Genetics
Cellular memory depending on phosphorylation states of a signaling protein
- Principal Investigator
  
  Sako Yasushi
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Biophysics
- Research Institution
  Institute of Physical and Chemical Research
Prediction and control of cellular response by measuring the conformation of RAFPrincipal Investigator
- Principal Investigator
  
  HIBINO Kayo
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biophysics
- Research Institution
  The Institute of Physical and Chemical Research
Conformational dynamics measurement of EGFR by high-speed single-molecule FRET measurement
- Principal Investigator
  
  OKAMOTO Kenji
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Nanomaterials/Nanobioscience
- Research Institution
  The Institute of Physical and Chemical Research
情報伝達蛋白質Raf1の分子内構造変化と活性調節の相関の細胞内1分子可視化解析Principal Investigator
- Principal Investigator
  
  日比野佳代
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (Start-up)
- Research Field
  
  Living organism molecular science
- Research Institution
  The Institute of Physical and Chemical Research

[Book] 細胞内情報処理反応の1分子計測：タンパク質ダイナミクスと分子認識　「１分子ナノバイオ計測」2014
- Author(s)
  佐甲靖志、廣島通夫、日比野佳代
- Total Pages
  10
- Publisher
  化学同人
- Data Source
  KAKENHI-PROJECT-24770161
[Book] 1分子FRET計測，「1分子生物学」2014
- Author(s)
  日比野佳代
- Total Pages
  9
- Publisher
  化学同人
- Data Source
  KAKENHI-PROJECT-24770161
[Book] Single-Molecule Imaging Measurements of Protein-Protein Interactions in Living Cells.2013
- Author(s)
  Hibino, K., Hiroshima, M., Nakamura Y., and Sako Y.
- Total Pages
  22
- Publisher
  InTech
- Data Source
  KAKENHI-PROJECT-24770161
[Journal Article] 1,6-hexanediol rapidly immobilizes and condenses chromatin in living human cells2021
- Author(s)
  Itoh Yuji、Iida Shiori、Tamura Sachiko、Nagashima Ryosuke、Shiraki Kentaro、Goto Tatsuhiko、Hibino Kayo、Ide Satoru、Maeshima Kazuhiro
- Journal Title
  
  Life Science Alliance
  
  Volume: 4 Issue: 4 Pages: e202001005-e202001005
- DOI
  10.26508/lsa.202001005
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K06594, KAKENHI-PROJECT-20J00572, KAKENHI-PROJECT-18K06187, KAKENHI-PLANNED-20H05936
[Journal Article] In-cell single-molecule FRET measurements reveal three conformational state changes in RAF protein2019
- Author(s)
  Okamoto Kenji、Hibino Kayo、Sako Yasushi
- Journal Title
  
  Biochimica et Biophysica Acta (BBA) - General Subjects
  
  Volume: in press Issue: 2 Pages: 1-42
- DOI
  10.1016/j.bbagen.2019.04.022
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H02394, KAKENHI-PROJECT-19H00987, KAKENHI-PROJECT-19H05647
[Journal Article] Conversion of graded phosphorylation into switch-like nuclear translocation via autoregulatory mechanisms in ERK signalling.2016
- Author(s)
  Y. Shindo, K. Iwamoto, K. Mouri, K. Hibino, M. Tomita, H. Kosako, Y. Sako and K. Takahashi.
- Journal Title
  
  Nature Communications
  
  Volume: 7 Issue: 1 Pages: 10485-10485
- DOI
  10.1038/ncomms10485
- NAID
  120006535049
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26440101, KAKENHI-PROJECT-15H02394, KAKENHI-PROJECT-14J03140
[Journal Article] Switching of the positive feedback for RAS activation by a concerted function of SOS membrane association domains.2016
- Author(s)
  Nakamura, Y., Hibino, K., Yanagida, T., and Sako, Y.
- Journal Title
  
  Biophys. Physicobiol.
  
  Volume: 13 Pages: 1-11
- NAID
  130005121334
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H02394
[Journal Article] Visualizing specific protein glycoforms by transmembrane fluorescence resonance energy transfer2012
- Author(s)
  Haga, Y., Ishii, K., Hibino, K., Sako, Y., Ito, Y., Taniguchi, N., Suzuki, T
- Journal Title
  
  Nature Communications
  
  Volume: 3 Issue: 1 Pages: 907-907
- DOI
  10.1038/ncomms1906
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J06185, KAKENHI-PROJECT-24770161
[Journal Article] Live cell single-molecule detection in systems biology2011
- Author(s)
  Sako, Y, Hiroshima, M., Pack, C.-G., Okamoto, K., Hibino, K., Yamamoto, A.
- Journal Title
  
  WIREs Systems Biology and Medicine
  
  Volume: 4 Issue: 2 Pages: 183-192
- DOI
  10.1002/wsbm.161
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22113523, KAKENHI-PROJECT-23650280, KAKENHI-PROJECT-24770161
[Journal Article] Single-molecule imaging analysis of interactions between signaling molecules Ras and Raf in living cells.2008
- Author(s)
  Kayo HIBINO
- Journal Title
  
  Biophysical Journal Supplement B270
- Data Source
  KAKENHI-PROJECT-18810042
[Journal Article] 情報伝達蛋白質Ras,Rafl相互作用のダイナミクスとキネティクス2006
- Author(s)
  日比野佳代
- Journal Title
  
  物性研究 86・1
  
  Pages: 46-51
- Data Source
  KAKENHI-PROJECT-18810042
[Presentation] Dynamic organization of human mitotic chromosomes2023
- Author(s)
  Hibino, K.
- Organizer
  Women and Future in Science seminar
- Invited
- Data Source
  KAKENHI-PROJECT-20K06594
[Presentation] Single molecule imaging sheds light on the mechanism of the human chromosome condensation.2022
- Author(s)
  Hibino, K.
- Organizer
  East Asian Single-Molecule Biophysics Symposium,
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-20H05936
[Presentation] Single nucleosome imaging during human chromosome condensation.2022
- Author(s)
  Hibino, K.
- Organizer
  44th Indian Biophysical Society Meeting
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-20H05936
[Presentation] Single nucleosome imaging during human chromosome condensation.2022
- Author(s)
  Hibino, K.
- Organizer
  44th Indian Biophysical Society Meeting
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K06594
[Presentation] Single molecule imaging unveils human chromosome condensation2022
- Author(s)
  Hibino, K., Sakai, Y., Kanemaki, M., Maeshima, K.
- Organizer
  The 60th Annual Meeting of the Biophysical Society of Japan
- Data Source
  KAKENHI-PROJECT-20K06594
[Presentation] 単一ヌクレオソームイメージングで捉えるヒト染色体凝縮2022
- Author(s)
  Hibino, K., Sakai, Y., Kanemaki, M., Maeshima, K.
- Organizer
  第74回日本細胞生物学会
- Data Source
  KAKENHI-PROJECT-20K06594
[Presentation] Single molecule imaging sheds light on the mechanism of the human chromosome condensation.2022
- Author(s)
  Hibino, K.
- Organizer
  2022 East Asian Single-Molecule Biophysics Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K06594
[Presentation] ヒト染色体中でコンデンシンはクロマチンの動きを束縛する2022
- Author(s)
  日比野佳代、境祐二、鐘巻将人、前島一博
- Organizer
  第45回日本分子生物学会年会 (MBSJ2022)
- Invited
- Data Source
  KAKENHI-PROJECT-20K06594
[Presentation] ヒト染色体凝縮過程の単一ヌクレオソームイメージング2022
- Author(s)
  日比野佳代、境祐二、鐘巻将人、前島一博
- Organizer
  第94回日本遺伝学会
- Invited
- Data Source
  KAKENHI-PROJECT-20K06594
[Presentation] Single molecule imaging unveils the dynamic organization of the human chromosomes.2021
- Author(s)
  Hibino, K.
- Organizer
  The 59th Annual Meeting of the Biophysical Society of Japan, Sendai
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-20H05936
[Presentation] Single nucleosome imaging sheds light on the dynamic organization of the human chromosomes.2021
- Author(s)
  Hibino, K.
- Organizer
  The 44th Annual Meeting of The Molecular Biology Society of Japan
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-20H05936
[Presentation] Single nucleosome imaging sheds light on the dynamic organization of the human chromosomes.2021
- Author(s)
  Hibino Kayo、Sakai Yuji、Kanemaki Masato、Maeshima Kazuhiro
- Organizer
  The 59th Annual Meeting of the Biophysical Society of Japan
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K06594
[Presentation] Single molecule imaging unveils the dynamic organization of the human chromosomes.2021
- Author(s)
  Hibino Kayo、Sakai Yuji、Kanemaki Masato、Maeshima Kazuhiro
- Organizer
  The 44th Annual Meeting of The Molecular Biology Society of Japan (MBSJ2021)
- Data Source
  KAKENHI-PROJECT-20K06594
[Presentation] Single nucleosome imaging sheds light on the dynamic organization of the human chromosomes2020
- Author(s)
  Hibino Kayo、Sakai Yuji、Kanemaki Masato、Maeshima Kazuhiro
- Organizer
  The 58th Annual Meeting of the Biophysical Society of Japan
- Invited
- Data Source
  KAKENHI-PROJECT-20K06594
[Presentation] Single-molecule analysis of a cell signaling protein, SOS2018
- Author(s)
  Nakamura, Y., Hibino, K., Yanagida, T., and Sako, Y.
- Organizer
  日本生物物理学会第56回年会
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02394
[Presentation] 情報伝達蛋白質RAFの疾病変異体のコンフォメーションと機能のイメージング計測2015
- Author(s)
  日比野佳代、上田昌宏、佐甲靖志
- Organizer
  第67回　日本細胞生物学会大会
- Place of Presentation
  タワーホール船堀、東京
- Year and Date
  2015-07-01
- Invited
- Data Source
  KAKENHI-PROJECT-15H02394
[Presentation] Polymorphism of a signaling protein RAF regulates cellular responses.2013
- Author(s)
  Hibino, K., Okamoto, K., Ueda, M., and Sako, Y.
- Organizer
  第51回日本生物物理学会年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-24770161
[Presentation] Single-molecule analysis of signaling protein RAF-conformation in living cells.2013
- Author(s)
  Hibino, K., Okamoto, K., Ueda, M., and Sako, Y.
- Organizer
  日本顕微鏡学会　第69回学術講演会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-24770161
[Presentation] The conformation of signaling molecule RAF and the cellular response2012
- Author(s)
  Hibino, K., Ueda, M., and Sako, M.
- Organizer
  RIKEN Quantitative Biology Center Inaugural Symposium "Towards Whole-Cell Modeling"
- Place of Presentation
  Kobe International Conference Center (Kobe)
- Data Source
  KAKENHI-PROJECT-24770161
[Presentation] Correlation between the molecular conformation and EGF response of RAF by FRET imaging in individual cells2012
- Author(s)
  日比野佳代、上田昌宏、佐甲靖志
- Organizer
  第50回日本生物物理学会年会
- Place of Presentation
  名古屋大学(名古屋)
- Data Source
  KAKENHI-PROJECT-24770161
[Presentation] 細胞内スペクトル計測を用いた情報伝達タンパク質RAFの構造とEGF応答の相関解析2012
- Author(s)
  日比野佳代
- Organizer
  理論と実験研究会
- Place of Presentation
  広島大学理学部(西条)
- Data Source
  KAKENHI-PROJECT-24770161
[Presentation] Correlation analysis of the molecular conformation and signal-responsiveness of RAF by FRET imaging in individual cells2012
- Author(s)
  Hibino, K., Ueda, M., and Sako, M.
- Organizer
  Joint Meeting of The 45th Annual Meeting of the Japanese Society of Developmental Biologists & The 64th Annual Meeting of the Japan Society for Cell Biology
- Place of Presentation
  Kobe International Conference Center (Kobe)
- Data Source
  KAKENHI-PROJECT-24770161
[Presentation] Signaling Molecule RAF: its conformation and cellular response2012
- Author(s)
  日比野佳代
- Organizer
  定量生物学の会第五回年会
- Place of Presentation
  東京大学駒場IIキャンパス生産技術研究所(東京)
- Data Source
  KAKENHI-PROJECT-24770161
[Presentation] Single-molecule imaging analysis of interactions between signaling molecules Ras and Raf in living cells.2008
- Author(s)
  Kayo HIBINO
- Organizer
  the Biophysical Society and the IUPAB
- Place of Presentation
  Long beach
- Data Source
  KAKENHI-PROJECT-18810042
[Presentation] 情報伝達タンパク質Ras, Raf1間の分子認識の細胞内1分子可視化解析2007
- Author(s)
  日比野佳代
- Organizer
  日本生物物理学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18810042
[Presentation] Conformation and function of disease-associated RAF mutants
- Author(s)
  Hibino, K., Ueda, M., and Sako, Y.
- Organizer
  第52回日本生物物理学会年会
- Place of Presentation
  札幌コンベンションセンター（北海道・札幌市）
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-24770161
[Presentation] Single-cell imaging analysis of conformation and function of disease-associated RAF mutants
- Author(s)
  Hibino, K., Ueda, M., and Sako, Y.
- Organizer
  第67回日本細胞生物学会大会
- Place of Presentation
  タワーホール船堀（東京・江戸川区）
- Year and Date
  2015-06-30 – 2015-07-02
- Data Source
  KAKENHI-PROJECT-24770161

1. OKAMOTO Kenji (40402763)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
2. Sako Yasushi (20215700)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
3. 前島一博 (00392118)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 杉山弘 (50183843)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 谷口雄一 (90556276)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 小迫英尊

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Hibino Kayo 日比野 佳代

HIBINO Kayo 日比野 佳代

日比野 佳代 ヒビノ カヨ

Research Projects

Research Products

Co-Researchers

Single molecule & super resolution imaging of chromatin networking through transcription hubs.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Modality of nucleosome dynamics

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Cellular memory depending on phosphorylation states of a signaling protein

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Prediction and control of cellular response by measuring the conformation of RAFPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Conformational dynamics measurement of EGFR by high-speed single-molecule FRET measurement

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

情報伝達蛋白質Raf1の分子内構造変化と活性調節の相関の細胞内1分子可視化解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 細胞内情報処理反応の1分子計測：タンパク質ダイナミクスと分子認識 「１分子ナノバイオ計測」2014

Author(s)

Total Pages

Publisher

Data Source

[Book] 1分子FRET計測，「1分子生物学」2014

Author(s)

Total Pages

Publisher

Data Source

[Book] Single-Molecule Imaging Measurements of Protein-Protein Interactions in Living Cells.2013

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] 1,6-hexanediol rapidly immobilizes and condenses chromatin in living human cells2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] In-cell single-molecule FRET measurements reveal three conformational state changes in RAF protein2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Conversion of graded phosphorylation into switch-like nuclear translocation via autoregulatory mechanisms in ERK signalling.2016

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Switching of the positive feedback for RAS activation by a concerted function of SOS membrane association domains.2016

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Visualizing specific protein glycoforms by transmembrane fluorescence resonance energy transfer2012

Author(s)

Hibino Kayo 日比野佳代

HIBINO Kayo 日比野佳代

日比野佳代ヒビノカヨ

[Book] 細胞内情報処理反応の1分子計測：タンパク質ダイナミクスと分子認識　「１分子ナノバイオ計測」2014