MIKUNI Shintaro 三國新太郎

Researcher Number	40435954
Other IDs
Affiliation (based on the past Project Information) *help	2016: 北海道大学, 先端生命科学研究科(研究院), 特任助教 2011 – 2012: 北海道大学, 医学(系)研究科(研究院), 特任助教 2009 – 2012: Hokkaido University, 大学院・医学研究科, 特任助教 2008: 北海道大学, 天学院・医学研究科, 特任助教
Review Section/Research Field	Principal Investigator Biophysics / Biological Sciences / Drug development chemistry Except Principal Investigator Nanomaterials/Nanobioscience / Biological Sciences
Keywords	Principal Investigator DNA / 相互作用 / FCCS / FCS / 生物物理 / 核内受容体 / 一分子計測 / 相関解析 / 転写活性 / 蛋白質 … More / 核酸 / 分子間相互作用 / バイオイメージング / 転写因子 / 核酸の構造・動態・機能 / タンパク質 / 単一分子計測 / 核内転写因子 / グルココルチコイド / 1分子計測 … More Except Principal Investigator 生物物理 / 空間光位相変調 / 空間相関 / 時間相関 / シグナル伝達 / 細胞・組織 / 可視化 / 1分子計測 / 分布関数 / タンパク質凝集体 / シャペロン / タンパク質相互作用 / 蛍光相互相関分析 / 1分子検出 / 酵母プリオン / 凝集タンパク質 / 一分子検出 / 分子集合体 / 蛍光測定 / 生体分子 Less

自己重合する蛋白質間相互作用の高精度定量に基づいた化合物スクリーニング法の確立Principal Investigator
- Principal Investigator
  
  三國新太郎
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Drug development chemistry
- Research Institution
  Hokkaido University
Establishment of simultaneous and quantitative assay for DNAbinding and transcriptional activity of glucocorticoid receptor.Principal Investigator
- Principal Investigator
  
  MIKUNI Shintaro
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biophysics
- Research Institution
  Hokkaido University
同一場における転写因子のDNA結合・転写活性同時評価法の確立Principal Investigator
- Principal Investigator
  
  三國新太郎
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Hokkaido University
多点時空間相関解析法による細胞内分子複合体研究
- Principal Investigator
  
  金城政孝
- Project Period (FY)
  2009 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Nanomaterials/Nanobioscience
- Research Institution
  Hokkaido University
Study of membrane binding protein complex using total internal reflection fluorescence correlation spectroscopy
- Principal Investigator
  
  KINJO Masataka
- Project Period (FY)
  2007 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Hokkaido University

All 2013 2012 2011 2010 2009 2007 Other

All Journal Article Presentation Book

[Book] First Steps for Fluorescence Correlation Spectroscopy of Living Cells(Live Cell Imaging -A Laboratory Manual- Edited by Goldman R, Swedolow J, Spector D.)2010
- Author(s)
  Kinjo M, Sakata H, Mikuni S.
- Publisher
  Cold Spring Harbor Laboratory Press
- Data Source
  KAKENHI-PLANNED-19058001
[Book] Live Cell Imaging(First Steps for Fluorescence Correlation Spectroscopy of Living Cells)2010
- Author(s)
  M. Kinjo, H. Sakata, S, Mikuni
- Publisher
  Cold Spring Harbor Laboratory Press
- Data Source
  KAKENHI-PLANNED-19058001
[Book] FCCSによるタンパク質相互作用解析(別冊分子間相互作用解析ハンドブック)2007
- Author(s)
  三國新太郎、小暮貴子、宮脇敦史、金城政孝
- Data Source
  KAKENHI-PLANNED-19058001
[Journal Article] Nonmuscle myosin II folds into a 10S form via two portions of tail for dynamic subcellular loacalization.2013
- Author(s)
  Kiboku T.
- Journal Title
  
  Genes to Cells.
  
  Volume: 18(2) Issue: 2 Pages: 90-109
- DOI
  10.1111/gtc.12021
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21221006, KAKENHI-PROJECT-22570129, KAKENHI-PROJECT-23590295, KAKENHI-PROJECT-23770169, KAKENHI-PROJECT-23770215, KAKENHI-PUBLICLY-25118502, KAKENHI-PROJECT-25650001, KAKENHI-PUBLICLY-23114701
[Journal Article] Monitoring the caspase cascade in single apoptotic cells using a three-color fluorescent protein substrate2011
- Author(s)
  Sun F, Mikuni S, Kinjo M.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 404(2) Pages: 706-710
- NAID
  120002834708
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19058001
[Journal Article] Monitoring the caspase cascade in single apoptotic cells using a three-color fluorescent protein substrate2011
- Author(s)
  Fan Sun, Shintaro Mikuni, Masataka Kinjo
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: Volume 404, Issue 2 Issue: 2 Pages: 706-710
- DOI
  10.1016/j.bbrc.2010.12.047
- NAID
  120002834708
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23770169
[Journal Article] Simultaneous measurement of the caspase-3 and caspase-9 activities during induced apoptosis by fluorescence cross-correlation spectroscopy2010
- Author(s)
  Sun F, Mikuni S, Kinjo M.
- Journal Title
  
  Bioimages
  
  Volume: 18 Pages: 1-9
- NAID
  130004845966
- URL
  https://www.jstage.jst.go.jp/article/bioimages/18/0/18_0_1/_article
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19058001
[Journal Article] Diffusion analysis of glucocorticoid receptor and antagonist effect in living cell nucleus.2007
- Author(s)
  Shintaro Mikuni
- Journal Title
  
  Experimental and Molecular Pathology 82
  
  Pages: 163-168
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19058001
[Journal Article] FCSによる解析法2007
- Author(s)
  三國新太郎
- Journal Title
  
  別冊「分子間相互相互作用解析ハンドブック」
  
  Pages: 85-89
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19058001
[Journal Article] FCCSによるタンパク質相互作用解析2007
- Author(s)
  三國新太郎
- Journal Title
  
  別冊「分子間相互相互作用解析ハンドブック」
  
  Pages: 95-95
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19058001
[Journal Article] Rab6a releases LIS1 from a dynein idling complex and activates dynein for retrograde movement.
- Author(s)
  Yamada M, Kumamoto K, Mikuni S, Arai Y, Kinjo M, Nagai T, Tsukasaki Y, Watanabe TM, Fukui M, Jin M, Toba S, Hirotsune S.
- Journal Title
  
  Scientific reports
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23770169
[Presentation] 蛍光相関分光法を用いたDNA-転写因子相互作用と転写活性化同時定量法の開発2013
- Author(s)
  三國新太郎
- Organizer
  先端的光イメージング拠点形成プロジェクト・成果報告シンポジウム
- Place of Presentation
  北海道大学(札幌市)
- Year and Date
  2013-03-18
- Data Source
  KAKENHI-PROJECT-23770169
[Presentation] Determination of dissociation constant between glucocorticoid receptor and DNA using FCCS2012
- Author(s)
  Shintaro Mikuni
- Organizer
  The 50th Annual Meeting of the Biophysical Society of Japan
- Place of Presentation
  名古屋大学（名古屋市）
- Data Source
  KAKENHI-PROJECT-23770169
[Presentation] Determination of dissociation constant between glucocorticoid receptor and DNA using FCCS2012
- Author(s)
  Mikuni S and Kinjo M
- Organizer
  第50回日本生物物理学会年会
- Place of Presentation
  名古屋大学(名古屋市)
- Data Source
  KAKENHI-PROJECT-23770169
[Presentation] Training course for FCS and FCCS2012
- Author(s)
  Shintaro Mikuni
- Organizer
  Fluorescence Microscopy: from Basics to Advanced
- Place of Presentation
  沖縄科学技術大学院大学（恩納村）
- Data Source
  KAKENHI-PROJECT-23770169
[Presentation] Training course for FCS and FCCS Fluorescence Microscopy: from Basics toAdvanced2012
- Author(s)
  Kinjo M and Mikuni S
- Place of Presentation
  沖縄科学技術大学院大学(恩納村)
- Data Source
  KAKENHI-PROJECT-23770169
[Presentation] Analysis for the relationship of intranuclear diffusional landscape and transcriptional activity of glucocorticoid receptor2011
- Author(s)
  Shintaro Mikuni
- Organizer
  International Symposium on Photonic Bioimaging
- Place of Presentation
  京王プラザホテル（札幌市）
- Data Source
  KAKENHI-PROJECT-23770169
[Presentation] The relationship between the landscape of the diffusion property and transcriptional activity of glucocorticoid recetor.2011
- Author(s)
  Shintaro Mikuni
- Organizer
  International Symposium Physicochemical Field for Genetic Activities
- Place of Presentation
  Awaji Yumebutai International Conference Center (Awaji, Japan)
- Year and Date
  2011-01-24
- Data Source
  KAKENHI-PLANNED-19058001
[Presentation] Fluorescence correlation analysis of intranuclear transcriptional activity of glucocorticoid receptor.2011
- Author(s)
  Shintaro Mikuni
- Organizer
  2^<nd> International Symposium on Photonic Bioimaging
- Place of Presentation
  Hilton Niseko Village (Niseko, Japan)(招待講演)
- Year and Date
  2011-02-10
- Data Source
  KAKENHI-PLANNED-19058001
[Presentation] Fluorescence correlation analysis of intranuclear transcriptional activity of glucocorticoid receptor.2011
- Author(s)
  Shintaro Mikuni
- Organizer
  2^<nd> International Symposium on Photonic Bioimaging
- Place of Presentation
  Hilton Niseko Village (Niseko, Japan) 招待講演
- Year and Date
  2011-02-10
- Data Source
  KAKENHI-PROJECT-21221006
[Presentation] Analysis for the relationship of intranuclrear diffusional landsdcape and transctiptional activity of glucocorticoid receptor2011
- Author(s)
  Shintaro Mikuni
- Organizer
  International Symposium on Photonic Bioimaging
- Place of Presentation
  京王プラザホテル札幌(北海道)
- Year and Date
  2011-10-22
- Data Source
  KAKENHI-PROJECT-21221006
[Presentation] Fluorescence correlation analysis of intranuclear transcriptional activity of glucocorticoid receptor.2011
- Author(s)
  Shintaro Mikuni
- Organizer
  2^<nd> International Symposium on Photonic Bioimaging
- Place of Presentation
  Hilton Niseko Village (Niseko, Japan)(招待講演)
- Year and Date
  2011-02-10
- Data Source
  KAKENHI-PUBLICLY-21114501
[Presentation] The relationship between the landscape of the diffusion property and transcriptional activity of glucocorticoid recetor.2011
- Author(s)
  Shintaro Mikuni
- Organizer
  International Symposium Physicochemical Field for Genetic Activities
- Place of Presentation
  Awaji Yumebutai International Conference Center (Awaji, Japan)
- Year and Date
  2011-01-24
- Data Source
  KAKENHI-PROJECT-21221006
[Presentation] Analysis for the relationship of intranuclrear diffusional landsdcape and transctiptional activity of glucocorticoid receptor2011
- Author(s)
  Shintaro Mikuni
- Organizer
  International Symposium on Photonic Bioimaging
- Place of Presentation
  京王プラザホテル札幌(北海道)
- Year and Date
  2011-10-22
- Data Source
  KAKENHI-PLANNED-19058001
[Presentation] The relationship between the landscape of the diffusion property and transcriptional activity of glucocorticoid recetor.2011
- Author(s)
  Shintaro Mikuni
- Organizer
  International Symposium Physicochemical Field for Genetic Activities
- Place of Presentation
  Awaji Yumebutai International Conference Center (Awaji, Japan)
- Year and Date
  2011-01-24
- Data Source
  KAKENHI-PUBLICLY-21114501
[Presentation] Imaging correlation analysis of intranuclear transcriptional activity of glucocorticoid receptor2010
- Author(s)
  Shintaro Mikuni
- Organizer
  日本生物物理学会第48回年会
- Place of Presentation
  東北大学川内北キャンパス(仙台市)
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PUBLICLY-21114501
[Presentation] Imaging correlation analysis of intranuclear transcriptional activity of glucocorticoid receptor2010
- Author(s)
  Shintaro Mikuni
- Organizer
  日本生物物理学会第48回年会
- Place of Presentation
  東北大学川内北キャンパス(仙台市)
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PLANNED-19058001
[Presentation] Imaging correlation analysis of intranuclear transcriptional activity of glucocorticoid receptor2010
- Author(s)
  Shintaro Mikuni
- Organizer
  日本生物物理学会第48回年会
- Place of Presentation
  東北大学川内北キャンパス(仙台市)
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-21221006
[Presentation] 蛍光相関分光法と蛍光寿命測定を組み合わせたホモ二量体定量法の確立2009
- Author(s)
  三國新太郎
- Organizer
  第6回バイオオプティクス研究会
- Place of Presentation
  北海道大学(札幌市)
- Year and Date
  2009-12-04
- Data Source
  KAKENHI-PLANNED-19058001
[Presentation] FCSとFLIMを組み合わせたホモ二量体検出法の確立2009
- Author(s)
  三國新太郎
- Organizer
  イメージング若手の会第1回光塾
- Place of Presentation
  情報通信研究機構(神戸市)
- Year and Date
  2009-08-15
- Data Source
  KAKENHI-PUBLICLY-21114501
[Presentation] FCSとFLIMを組み合わせたホモ二量体検出法の確立2009
- Author(s)
  三國新太郎
- Organizer
  第1回光塾
- Place of Presentation
  情報通信研究機構(神戸市)
- Year and Date
  2009-08-16
- Data Source
  KAKENHI-PLANNED-19058001
[Presentation] 蛍光相関分光法と蛍光寿命測定を組み合わせたホモ二量体定量法の確立2009
- Author(s)
  三國新太郎
- Organizer
  第6回バイオオプティクス研究会
- Place of Presentation
  北海道大学(札幌市)
- Year and Date
  2009-12-04
- Data Source
  KAKENHI-PUBLICLY-21114501
[Presentation] 蛍光相関分光法を用いたDNA-転写因子相互作用と転写活性化同時定量法の開発
- Author(s)
  三國新太郎
- Organizer
  先端的光イメージング拠点形成プロジェクト・成果報告シンポジウム
- Place of Presentation
  北海道大学（札幌市）
- Data Source
  KAKENHI-PROJECT-23770169

1. KINJO Masataka (70177971)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
2. KITAMURA Akira (10580152)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. 児玉耕太 (90419424)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

MIKUNI Shintaro 三國 新太郎

Research Projects

Research Products

Co-Researchers

自己重合する蛋白質間相互作用の高精度定量に基づいた化合物スクリーニング法の確立Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Establishment of simultaneous and quantitative assay for DNAbinding and transcriptional activity of glucocorticoid receptor.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

同一場における転写因子のDNA結合・転写活性同時評価法の確立Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

多点時空間相関解析法による細胞内分子複合体研究

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study of membrane binding protein complex using total internal reflection fluorescence correlation spectroscopy

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Book] First Steps for Fluorescence Correlation Spectroscopy of Living Cells(Live Cell Imaging -A Laboratory Manual- Edited by Goldman R, Swedolow J, Spector D.)2010

Author(s)

Publisher

Data Source

[Book] Live Cell Imaging(First Steps for Fluorescence Correlation Spectroscopy of Living Cells)2010

Author(s)

Publisher

Data Source

[Book] FCCSによるタンパク質相互作用解析(別冊 分子間相互作用解析ハンドブック)2007

Author(s)

Data Source

[Journal Article] Nonmuscle myosin II folds into a 10S form via two portions of tail for dynamic subcellular loacalization.2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Monitoring the caspase cascade in single apoptotic cells using a three-color fluorescent protein substrate2011

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Monitoring the caspase cascade in single apoptotic cells using a three-color fluorescent protein substrate2011

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Simultaneous measurement of the caspase-3 and caspase-9 activities during induced apoptosis by fluorescence cross-correlation spectroscopy2010

Author(s)

Journal Title

NAID

URL

Data Source

[Journal Article] Diffusion analysis of glucocorticoid receptor and antagonist effect in living cell nucleus.2007

Author(s)

Journal Title

Data Source

[Journal Article] FCSによる解析法2007

Author(s)

Journal Title

Data Source

[Journal Article] FCCSによるタンパク質相互作用解析2007

Author(s)

Journal Title

Data Source

[Journal Article] Rab6a releases LIS1 from a dynein idling complex and activates dynein for retrograde movement.

MIKUNI Shintaro 三國新太郎

[Book] FCCSによるタンパク質相互作用解析(別冊分子間相互作用解析ハンドブック)2007