SEKIKAWA Akira 関川昭

Researcher Number	40438693
Affiliation (based on the past Project Information) *help	2007 – 2010: Dokkyo Medical University, 医学部, 助教
Review Section/Research Field	Principal Investigator Gastroenterology
Keywords	Principal Investigator STAT3 / IL-22 / 潰瘍性大腸炎 / Reg Iα / 発癌 / 抗アポトーシス / REG Iα / 胃癌 / IL-22リセプター / REG … More / 発現制御 / シグナル伝達 / 遺伝子 / 癌 Less

Research Projects
(2 results)
Research Products
(24 results)

潰瘍性大腸炎におけるIL-22/RegIα蛋白の粘膜保護作用Principal Investigator
- Principal Investigator
  
  関川昭
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Dokkyo Medical University
An anti-apoptotic effect of Reg Iα proteinPrincipal Investigator
- Principal Investigator
  
  SEKIKAWA Akira
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Dokkyo Medical University

All 2010 2009 2008 2007

All Journal Article Presentation Book

[Book] G. I. Research2008
- Author(s)
  関川昭,福井広一,千葉勉
- Publisher
  先端医学社
- Data Source
  KAKENHI-PROJECT-19790494
[Book] G.I. Research2008
- Author(s)
  関川昭
- Total Pages
  5
- Publisher
  先端医学社
- Data Source
  KAKENHI-PROJECT-19790494
[Book] 医学のあゆみ2007
- Author(s)
  関川昭,千葉勉
- Publisher
  医歯薬出版
- Data Source
  KAKENHI-PROJECT-19790494
[Book] 医学のあゆみ2007
- Author(s)
  関川昭
- Total Pages
  3
- Publisher
  医歯薬出版社
- Data Source
  KAKENHI-PROJECT-19790494
[Journal Article] Involvement of IL22/REG Iα axis in ulcerative colitis.2010
- Author(s)
  Sekikawa A
- Journal Title
  
  Lab Invest 90
  
  Pages: 496-505
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790684
[Journal Article] Role of Necl-5 in the pathophysiology of colorectal lesions induced by dimethylhydrazine and/or dextran sodium sulphate2009
- Author(s)
  Abe A, Fukui H, Fujii S, Kono T, Mukawa K, Yoshitake N, Sekikawa A, Ichikawa K, Tomita S, Yamagishi H, Imai Y, Shinoda M, Ishizaki H,Tanaka-Okamoto M, Kubota K, Miyoshi J, Takai Y and Fujimori T.
- Journal Title
  
  J Pathol 217
  
  Pages: 42-53
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790494
[Journal Article] Involvement of REG lαprotein in the regeneration of ductal epithelial cells in the minor salivary glands of patients with Sjogren' s syndrome2009
- Author(s)
  Kimura T, Fukui H, Sekikawa A, Yamagishi H, Ichikawa K, Tomita S, Fujii S, Imura J, Kawamata H, Chiba T, Imai Y and Fujimori T.
- Journal Title
  
  Clin Exp Immunol 155
  
  Pages: 16-20
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790494
[Journal Article] Expression profile of REG family protein Ialpha and REG IV in advanced gastric cancer: comparison with mucin phenotype and prognostic markers.2009
- Author(s)
  Yamagishi H, Fukui H, Sekikawa A, Kono T, Fujii S, Ichikawa K, Tomita S,Imura J, Hiraishi H, Chiba T, Fujimori T.
- Journal Title
  
  Mod Pathol (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790494
[Journal Article] REG lα protein mediates an anti-apoptotic effect of STAT3 signaling in gastric cancer cells2008
- Author(s)
  Sekikawa A, Fukui H, Fujii S, Ichikawa K, Tomita S, Imura J, Chiba T and Fujimori T
- Journal Title
  
  Carcinogenesis 29
  
  Pages: 76-83
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790494
[Journal Article] Exprssion of SDF-1 alpha and nuclear CXCR4 predicts lymph node metastasis in colorectal cancer.2008
- Author(s)
  Yoshitake N, Fukui H, Yamagishi H, Sekikawa A, Fujii S, Tomita S, Ichikawa K, Imura J, Hiraishi H and Fujimori T.
- Journal Title
  
  Br J Cancer 98
  
  Pages: 1682-1689
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790494
[Journal Article] REG Iα protein mediates an anti-apoptotic effect of STAT3 signaling in gastric cancer cells2008
- Author(s)
  Sekikawa A
- Journal Title
  
  Carcinogenesis 29
  
  Pages: 76-83
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790494
[Journal Article] EXTL3 promoter methylation down-regulates EXTL3 and heparin sulphate expression in mucinous colorectal cancers.2008
- Author(s)
  Karibe T, Fukui H, Sekikawa A, Shiratori K and Fujimori T.
- Journal Title
  
  J Pathol 216
  
  Pages: 32-42
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790494
[Journal Article] Inhibitory effects of the cyclooxygenase-2 inhibitor, etodolac, on colitis-associated tumorigenesis in p53-deficient mice treated with dextran sulfate sodium.2008
- Author(s)
  Mukawa K, Fujii S, Tominaga K, Yoshitake N, Abe A, Kono T, Sekikawa A, Fukui H, Ichikawa K, Tomita S, Imura J, Ono Y, Shinoda M, Hiraishi H and Fujimori T.
- Journal Title
  
  Oncol Rep 19
  
  Pages: 393-399
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790494
[Journal Article] Nuclear expression of phosphorylated EGFR is associated with poor prognosis of patients with esophageal squamous cell carcinoma.2007
- Author(s)
  Hoshino M, Fukui H, Ono Y, Sekikawa A, Ichikawa K, Tomita S, Imai Y, Imura J, Hiraishi H and Fujimori T.
- Journal Title
  
  Pathobiology 74
  
  Pages: 15-21
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790494
[Journal Article] Expression of REG IV gene in ulcerative colitis.2007
- Author(s)
  Nanakin A, Fukui H, Fujii S, Sekikawa A, Kanda N, Hisatsune H, Seno H, Konda Y, Fujimori T and Chiba T.
- Journal Title
  
  Lab Invest 87
  
  Pages: 304-314
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790494
[Journal Article] Human papillomavirus infection is involved in the development of colonic squamous cell dysplasia in ulcerative colitis-associated carcinogenesis.2007
- Author(s)
  Yoshitake N, Fukui H, Fujii S, Mukawa K, Tominaga K, Sekikawa A, Tomita S,Ichikawa K, Imura J, Nakajima K, Nezu R, Yamada Y, Yoshihara H, Hiraishi H and Fujimori T.
- Journal Title
  
  Inflamm Bowel Dis 13
  
  Pages: 1319-1321
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790494
[Journal Article] Colonic expression of heme oxygenase-1 is associated with a better long-term survival in patients with colorectal cancer.2007
- Author(s)
  Becker JC, Fukui H, Imai Y, Sekikawa A, Kimura T, Yamagishi H, Yoshitake N, Pohle T, Domschke W and Fujimori T.
- Journal Title
  
  Scan J Gastroenterol 42
  
  Pages: 853-858
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790494
[Presentation] DMBTI is a novel gene induced by IL-22 in colon cancer cells.2009
- Author(s)
  関川昭
- Organizer
  第68回日本癌学会総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2009-10-02
- Data Source
  KAKENHI-PROJECT-21790684
[Presentation] 潰瘍性大腸炎におけるDMBTI遺伝子発現2009
- Author(s)
  関川昭
- Organizer
  第97回日本病理学会総会
- Place of Presentation
  京都国際会館
- Year and Date
  2009-05-02
- Data Source
  KAKENHI-PROJECT-21790684
[Presentation] REG Ia protein is up-regulated by IL-6/STAT3 signaling in gastric cancer cells2008
- Author(s)
  Sekikawa A
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2008-10-28
- Data Source
  KAKENHI-PROJECT-19790494
[Presentation] REG Ia protein is up-regulated by IL-6/STAT3 signaling in gastric cancer cells.2008
- Author(s)
  Akira Sekikawa, Hirokazu Fukui,Shigeki Tomita, Kazuhito Ichikawa, Shigeki Tomita, Johji Imura、
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2008-10-28
- Data Source
  KAKENHI-PROJECT-19790494
[Presentation] 潰瘍性大腸炎におけるIL-22およびREG Iα遺伝子発現2008
- Author(s)
  関川昭
- Organizer
  第97回日本病理学会総会
- Place of Presentation
  金沢もてなしドーム
- Year and Date
  2008-05-15
- Data Source
  KAKENHI-PROJECT-19790494
[Presentation] STAT3シグナルによるREGIα蛋白発現制御について2007
- Author(s)
  関川昭,福井広一,苅部豊彦,木村時子,山岸秀嗣,冨田茂樹,市川一仁,小野祐子,今井康雄,井村穣二,藤盛孝博.
- Organizer
  第96回日本病理学会総会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2007-03-13
- Data Source
  KAKENHI-PROJECT-19790494
[Presentation] STAT3 シグナルによる REG Iα蛋白発現制御2007
- Author(s)
  関川昭
- Organizer
  第96回日本病理学会総会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2007-03-13
- Data Source
  KAKENHI-PROJECT-19790494

SEKIKAWA Akira 関川 昭

Research Projects

Research Products

潰瘍性大腸炎におけるIL-22/RegIα蛋白の粘膜保護作用Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

An anti-apoptotic effect of Reg Iα proteinPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] G. I. Research2008

Author(s)

Publisher

Data Source

[Book] G.I. Research2008

Author(s)

Total Pages

Publisher

Data Source

[Book] 医学のあゆみ2007

Author(s)

Publisher

Data Source

[Book] 医学のあゆみ2007

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Involvement of IL22/REG Iα axis in ulcerative colitis.2010

Author(s)

Journal Title

Data Source

[Journal Article] Role of Necl-5 in the pathophysiology of colorectal lesions induced by dimethylhydrazine and/or dextran sodium sulphate2009

Author(s)

Journal Title

Data Source

[Journal Article] Involvement of REG lαprotein in the regeneration of ductal epithelial cells in the minor salivary glands of patients with Sjogren' s syndrome2009

Author(s)

Journal Title

Data Source

[Journal Article] Expression profile of REG family protein Ialpha and REG IV in advanced gastric cancer: comparison with mucin phenotype and prognostic markers.2009

Author(s)

Journal Title

Data Source

[Journal Article] REG lα protein mediates an anti-apoptotic effect of STAT3 signaling in gastric cancer cells2008

Author(s)

Journal Title

Data Source

[Journal Article] Exprssion of SDF-1 alpha and nuclear CXCR4 predicts lymph node metastasis in colorectal cancer.2008

Author(s)

Journal Title

Data Source

[Journal Article] REG Iα protein mediates an anti-apoptotic effect of STAT3 signaling in gastric cancer cells2008

Author(s)

Journal Title

Data Source

[Journal Article] EXTL3 promoter methylation down-regulates EXTL3 and heparin sulphate expression in mucinous colorectal cancers.2008

Author(s)

Journal Title

Data Source

[Journal Article] Inhibitory effects of the cyclooxygenase-2 inhibitor, etodolac, on colitis-associated tumorigenesis in p53-deficient mice treated with dextran sulfate sodium.2008

Author(s)

Journal Title

Data Source

[Journal Article] Nuclear expression of phosphorylated EGFR is associated with poor prognosis of patients with esophageal squamous cell carcinoma.2007

Author(s)

Journal Title

Data Source

[Journal Article] Expression of REG IV gene in ulcerative colitis.2007

Author(s)

Journal Title

Data Source

[Journal Article] Human papillomavirus infection is involved in the development of colonic squamous cell dysplasia in ulcerative colitis-associated carcinogenesis.2007

Author(s)

Journal Title

SEKIKAWA Akira 関川昭