Yasuda Takako 保田隆子

… Alternative Names

保田隆子ヤスダタカコ

YASUDA Takako 保田隆子

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Researcher Number	40450431
Affiliation (Current)	2025: 日本女子大学, 理学部, 研究員
Affiliation (based on the past Project Information) *help	2021 – 2023: 日本女子大学, 理学部, 研究員 2018 – 2019: 東京大学, 大学院新領域創成科学研究科, 特任准教授 2017: 東京大学, 大学院新領域創成科学研究科, 研究員 2016 – 2017: 東京大学, 大学院新領域創成科学研究科, 特任研究員 2012 – 2015: 東京大学, 新領域創成科学研究科, 特任研究員 2014: 東京大学, 大学院新領域創成科学研究科, 特任研究員 2010 – 2012: 東京大学, 大学院・新領域創成科学研究科, 特任研究員
Review Section/Research Field	Principal Investigator Basic Section 63020:Radiation influence-related / Risk sciences of radiation and chemicals / 宇宙生命学 / Risk sciences of radiation/Chemicals Except Principal Investigator Risk sciences of radiation and chemicals / Risk sciences of radiation/Chemicals
Keywords	Principal Investigator 放射線 / ミクログリア / 脳内免疫細胞 / メダカ胚 / 貪食 / アポトーシス / マイクログリア / ApoE / 脳 / 放射線損傷 … More / メダカ / 薬剤スクリーニング / サイトカインストーム / 免疫暴走 / 免疫細胞 / Lplastin遺伝子 / ApoE遺伝子 / 脳内炎症 / サイトカイン / 脳腫瘍放射線治療 / in situ　ハイブリダイゼーション / 神経細胞 / 網膜 / 細胞増殖 / 幹細胞 / 免疫組織化学 / Ascl1a / SOX２ / リプログラミング / 分化転換 / ミュラーグリア細胞 / メダカ胚網膜 / トランスジェニック / Lplastin / トランスジェニックメダカ / ライブイメージング / 胚 / 未熟な脳 / 脳内免疫 / whole-mount in situハイブリダイゼーション / p53 / 発達神経毒性 / 放射線傷害 / 神経細胞傷害 … More Except Principal Investigator 突然変異 / 放射線 / 組織幹細胞 / in vivo / GFP / リスク評価 / 遺伝子 / 環境 / ゲノム解析 / 環境変異原 / 遺伝影響評価 / 生殖細胞突然変異 / 体細胞突然変異 / トランスジェニックメダカ / ノックインマウス / 放射線誘発突然変異 / DNA修復 / 咽頭歯 / 生殖細胞 / 細胞死 / マウス / メダカ Less

A trial to regulate microglial activation in medaka embryo as a model to avoid cytokine stormPrincipal Investigator
- Principal Investigator
  
  保田隆子
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 63020:Radiation influence-related
- Research Institution
  Japan Women's University
Live imaging for activated microglia in response to radiation-induced brain injury by utilizing transgenic medakaPrincipal Investigator
- Principal Investigator
  
  Yasuda Takako
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Risk sciences of radiation and chemicals
- Research Institution
  The University of Tokyo
Embryonic medaka model of microglia in the developing CNS allowing in vivo analysis of their spatiotemporal recruitment in response to cosmic radiationPrincipal Investigator
- Principal Investigator
  
  Yasuda Takako
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  宇宙生命学
- Research Institution
  The University of Tokyo
In vivo, in situ assessment of the mutagenic risk of radiation and environmental chemicals, using newly developed animal systems
- Principal Investigator
  
  NODA Asao
- Project Period (FY)
  2013 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Risk sciences of radiation and chemicals
- Research Institution
  Radiation Effects Research Foundation
microglial behavior in irradiation-injured developing brain using medaka, a vertebrate modelPrincipal Investigator
- Principal Investigator
  
  YASUDA Takako
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  The University of Tokyo
Visualization of radiation induced mutagenesis in vivo
- Principal Investigator
  
  MITANI Hiroshi
- Project Period (FY)
  2009 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  The University of Tokyo

[Journal Article] 3D reconstructed brain images reveal the possibility of the ogg1 gene to suppress the irradiation-induced apoptosis in embryonic brain in medaka (Oryzias latipes)2022
- Author(s)
  Takako Yasuda, Duolin Li, Erge Sha, Fumitaka Kakimoto, Hiroshi Mitani, Hiroshi Yamamoto, Tomoko Ishikawa-Fujiwara, Takeshi Todo, Shoji Oda
- Journal Title
  
  JOURNAL OF RADIATION RESEARCH
  
  Volume: - Issue: 3 Pages: 1-12
- DOI
  10.1093/jrr/rrac005
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H04268, KAKENHI-PROJECT-21K12237, KAKENHI-PROJECT-20H00631
[Journal Article] Radical change of apoptotic strategy following irradiation during later period of embryogenesis in medaka (Oryzias latipes)2018
- Author(s)
  Yasuda Takako、Ishikawa Yuta、Shioya Noriko、Itoh Kazusa、Kamahori Miyuki、Nagata Kento、Takano Yoshiro、Mitani Hiroshi、Oda Shoji
- Journal Title
  
  PLOS ONE
  
  Volume: 13 Issue: 8 Pages: e0201790-e0201790
- DOI
  10.1371/journal.pone.0201790
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K00541, KAKENHI-PROJECT-18H04135
[Journal Article] メダカ胚で明らかになった放射線により活性化された脳内免疫細胞ミクログリアの動態2018
- Author(s)
  保田隆子、舟山知夫、三谷啓志、尾田正二
- Journal Title
  
  放射線生物研究
  
  Volume: 53 Pages: 31-43
- NAID
  40021567236
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K00541
[Journal Article] Abscopal Activation of Microglia in Embryonic Fish Brain Following Targeted Irradiation with Heavy-Ion Microbeam.2017
- Author(s)
  Yasuda T, Kamahori M, Nagata K, Watanabe-Asaka T, Suzuki M, Funayama T, Mitani H, Oda S.
- Journal Title
  
  Int J Mol Sci.
  
  Volume: 18(7) Issue: 7 Pages: 1428-1428
- DOI
  10.3390/ijms18071428
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K00541, KAKENHI-PROJECT-16K00552
[Journal Article] In vivo 3D analysis of systemic effects after local heavy-ion beam irradiation in an animal model2016
- Author(s)
  Nagata K, Hashimoto C, Watanabe-Asaka T, Itoh K, Yasuda T, Ohta K, Oonishi H, Igarashi K, Suzuki M, Funayama T, Kobayashi Y, Nishimaki T, Katsumura T, Oota H, Ogawa M, Oga A, Ikemoto K, Itoh H, Kutsuna N, Oda S, and Mitani H
- Journal Title
  
  Scientific Reports
  
  Volume: 6 Issue: 1 Pages: 28691-28691
- DOI
  10.1038/srep28691
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25220102, KAKENHI-PROJECT-25251046, KAKENHI-PROJECT-26251050, KAKENHI-PROJECT-16J07227, KAKENHI-PROJECT-15K12201, KAKENHI-PROJECT-16K00552, KAKENHI-PROJECT-16K18562, KAKENHI-PROJECT-16K21352
[Journal Article] Irradiation-injured brain tissues normally self-renewed in the absence of p53, the pivotal tumor suppressor, in medaka (Oryzias latipes) embryo.2016
- Author(s)
  Yasuda T., Kimori Y., Nagata K., Igarashi K., Kakimoto F., Watanabe-Asaka T., Oda S., Mitani H.
- Journal Title
  
  J Radiat Res
  
  Volume: 57 Issue: 1 Pages: 9-15
- DOI
  10.1093/jrr/rrv054
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K12201, KAKENHI-PROJECT-25220102, KAKENHI-PROJECT-25514002, KAKENHI-PROJECT-25860177
[Journal Article] Embryonic medaka model of microglia in the developing CNS allowing in vivo analysis of their spatiotemporal recruitment in response to irradiation2015
- Author(s)
  Takako Yasuda, Shoji Oda, Yusuke Hibi, Satomi Satoh, Kento Nagata,　Kei Hirakawa,　Natsumaro Kutsuna, Hiroshi Sagara & Hiroshi Mitani
- Journal Title
  
  Plos one
  
  Volume: 印刷中
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25514002
[Journal Article] Embryonic medaka model of microglia in the developing CNS allowing in vivo analysis of their spatiotemporal recruitment in response to irradiation.2015
- Author(s)
  Yasuda T., Oda S., Hibi Y., Satoh S., Nagata K., Hirakawa K., Kutsuna N., Sagara H., Mitani H.
- Journal Title
  
  Plos one
  
  Volume: 10 (6)
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25514002
[Journal Article] Embryonic Medaka Model of Microglia in the Developing CNS Allowing In Vivo Analysis of Their Spatiotemporal Recruitment in Response to Irradiation2015
- Author(s)
  Yasuda T, Oda S, Hibi Y, Satoh S, Nagata K, Hirakawa K, Kutsuna N, Sagara H and Mitani H
- Journal Title
  
  Plos One
  
  Volume: 10:6 Issue: 6 Pages: 1-16
- DOI
  10.1371/journal.pone.0127325
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25220102
[Journal Article] Regular heartbeat rhythm at the heartbeat initiation stage is essential for normal cardiogenesis at low temperature.2014
- Author(s)
  Watanabe-Asaka, T., Y. Sekiya, H. Wada, T. Yasuda, I. Okubo, S. Oda and H. Mitani
- Journal Title
  
  BMC Dev Biol
  
  Volume: 14 Issue: 1 Pages: 12-12
- DOI
  10.1186/1471-213x-14-12
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-21221003, KAKENHI-PROJECT-24310039, KAKENHI-PROJECT-25220102, KAKENHI-PROJECT-25860177
[Journal Article] Gamma-ray irradiation promotes premature meiosis of spontaneously differentiating testis–ova in the testis of p53-deficient medaka (Oryzias latipes)2012
- Author(s)
  Yasuda, T
- Journal Title
  
  Cell Death and Disease
  
  Volume: 3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21221003
[Journal Article] メダカ胚発生中の脳で起こる放射線誘発アポトーシスのin vivoイメージング2011
- Author(s)
  保田隆子
- Journal Title
  
  放射線生物研究
  
  Volume: 46 Pages: 15-29
- NAID
  40018784404
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21221003
[Journal Article] メダカ胚八世中の脳で起こる放射線誘発アポトーシスのinvivoイメージング2011
- Author(s)
  保田隆子, ら
- Journal Title
  
  放射線生物研究
  
  Volume: 46 Pages: 15-29
- Data Source
  KAKENHI-PROJECT-21221003
[Journal Article] Neurocytotoxic Effects of Iron-Ions on the Developing Brain Measured In Vivo Using Medaka (Oryzias latipes), a Vertebrate Model2011
- Author(s)
  Yasuda T., Oda S., Yasuda H., Hibi Y., Anzai K., Mitani H
- Journal Title
  
  International journal of radiation biology
  
  Volume: 87 Pages: 915-922
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22510056
[Journal Article] Neurocytotoxic effects of iron-ions on the developing brain measured in vivo using medaka (Oryzias latipes), a vertebrate model2011
- Author(s)
  Yasuda, T.
- Journal Title
  
  Int.J.Radiat.Biol.
  
  Volume: 87 Issue: 9 Pages: 915-922
- DOI
  10.3109/09553002.2011.584944
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21221003
[Journal Article] Neurocytotoxic effects of iron-ions on the developing brain measured in vivo using Medaka (Oryzias latipes), a vertebrate model2011
- Author(s)
  Yasuda, et al.
- Journal Title
  
  Int.J.Radiat.Biol
  
  Volume: (掲載確定)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21221003
[Journal Article] Live imaging of radiation-induced apoptosis by yolk injection of Acridine Orange in the developing optic tectum of medaka.2009
- Author(s)
  Yasuda, T., et al.
- Journal Title
  
  J Radiat Res(Tokyo) 50
  
  Pages: 487-494
- NAID
  10025912894
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21221003
[Presentation] Retinal regeneration after injury induced by gamma-ray irradiation during early embryogenesis in medaka, Oryzias latipes2024
- Author(s)
  Takako Yasuda
- Organizer
  国際放射線神経生物学会
- Data Source
  KAKENHI-PROJECT-21K12237
[Presentation] A trial to control microglial activation in irradiated medaka embryo as a model to suppress prolonged inflammation in CNS2023
- Author(s)
  Takako Yasuda
- Organizer
  国際放射線神経生物学会
- Data Source
  KAKENHI-PROJECT-21K12237
[Presentation] マイクロビーム照射により明らかになったメダカ胚発生を決定する胚盤細胞の損傷割合2021
- Author(s)
  保田隆子、舟山知夫、鈴木芳代、尾田正二
- Organizer
  マイクロビーム生物研究会
- Invited
- Data Source
  KAKENHI-PROJECT-21K12237
[Presentation] メダカ胚で明らかになった放射線照射により活性化したミクログリアの動態2021
- Author(s)
  保田隆子
- Organizer
  日本量子医科学会
- Invited
- Data Source
  KAKENHI-PROJECT-21K12237
[Presentation] Dynamics of activated microglia in response to radiation-induced brain injury2020
- Author(s)
  Takako Yasuda
- Organizer
  ElyT meeting
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K00541
[Presentation] Specific Recruitment of Brain Immune Cell of Microglia Following Irradiation-Induced Brain Injury in Embryonic Medaka Model2020
- Author(s)
  Takako Yasuda
- Organizer
  第10回国際放射線神経生物学会大会
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K00541
[Presentation] SOX2 expressing Muller glia is essential for tissue regeneration in irradiated embryonic retina of medaka (Oryzias latipes)2019
- Author(s)
  Takako Yasuda*, Takuya Nakazawa, Kei Hirakawa, Kento Nagata, Hiroshi Mitani and Shoji Oda
- Organizer
  国際放射線神経生物学会大会
- Data Source
  KAKENHI-PROJECT-16K00541
[Presentation] メダカ胚で明らかになった放射線損傷した網膜の再生へ寄与するSOX2発現前駆細胞2019
- Author(s)
  保田隆子、中澤拓哉、三谷啓志、尾田正二
- Organizer
  第62回大会日本放射線影響学会
- Data Source
  KAKENHI-PROJECT-16K00541
[Presentation] メダカ胚網膜で見出された休止組織幹細胞の増殖再開による放射線損傷の修復機構2018
- Author(s)
  保田隆子、平川慶、中澤拓哉、釜堀みゆき、永田健斗、三谷啓志、尾田正二
- Organizer
  日本放射線影響学会
- Data Source
  KAKENHI-PROJECT-16K00541
[Presentation] Retinal regeneration by ectopic proliferation of SOX2-positive Muller glia cells in embryonic retina of medaka (Oryzias latipes)2018
- Author(s)
  Takako Yasuda, Kei Hirakawa, Kento Nagata, Takuya Nakazawa, Hiroshi Mitani and Shoji Oda
- Organizer
  小型魚類研究会
- Data Source
  KAKENHI-PROJECT-16K00541
[Presentation] Medaka embryo at blastula stage can restore the irradiation-induced damages and avoid malformations but late stage embryo cannot do so2018
- Author(s)
  Takako Yasuda, Kento Nagata, Michiyo Suzuki, Tomoo Funayama, Hiroshi Mitani, Shoji Oda
- Organizer
  第8回国際放射線神経生物学会大会
- Data Source
  KAKENHI-PROJECT-16K00541
[Presentation] Embryonic medaka model unveiling efficient apoptotic cell clearance by specific microglial recruitment in response to irradiation2017
- Author(s)
  Takako Yasuda
- Organizer
  国際放射線神経生物学会
- Place of Presentation
  ホテル双葉（新潟県湯沢市）
- Year and Date
  2017-02-09
- Data Source
  KAKENHI-PROJECT-16K00541
[Presentation] Abscopal Activated Immune Cell of Microglia Following Targeted Irradiation with Heavy-Ion Microbeam in Embryonic Fish Brain2017
- Author(s)
  Takako Yasuda
- Organizer
  63rd Annual International Meeting of Radiation Research Society
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K00541
[Presentation] 量子ビーム技術を活用した放射線生物物理学の最前線；メダカ胚で観察された重イオン局所照射によって誘発される照射野以外への影響2017
- Author(s)
  保田隆子、尾田正二、舟山知夫、三谷啓志
- Organizer
  第55回日本生物物理学会
- Invited
- Data Source
  KAKENHI-PROJECT-16K00541
[Presentation] メダカを利用した造血組織への局所照射系の確立と放射線感受性の解析2017
- Author(s)
  浅香智美、大橋圭太、梶原尭之、橋本知佳、永田健斗、保田隆子、舟山知夫、鈴木芳代、尾田正二、三谷啓志
- Organizer
  日本放射線影響学会
- Data Source
  KAKENHI-PROJECT-25220102
[Presentation] メダカ胞胚期における致死線量以下の放射線被ばくは孵化時の脳の形態形成異常を誘導しない2017
- Author(s)
  保田隆子, 永田健斗, 釜堀みゆき, 鈴木芳代 , 横田裕一郎 , 舟山知夫 , 尾田正二, 三谷啓志
- Organizer
  日本放射線影響学会第60回大会
- Data Source
  KAKENHI-PROJECT-16K00541
[Presentation] メダカ胚をモデルとした小児がん脳腫瘍放射線照射に伴う脳内免疫細胞ミクログリアの応答2016
- Author(s)
  保田隆子、五十嵐健人、浅香智美、永田健斗、鈴木芳代、横田裕一郎、尾田正二、舟山知夫、三谷啓志
- Organizer
  日本放射線腫瘍学会生物部会学術大会
- Place of Presentation
  I-site なんば（大阪府大阪市）
- Year and Date
  2016-07-15
- Data Source
  KAKENHI-PROJECT-16K00541
[Presentation] メダカ胚をモデルとした免疫細胞ミクログリアの放射線応答と脳腫瘍治療への応用2016
- Author(s)
  保田隆子、五十嵐健人、舟山知夫、尾田正二、三谷啓志
- Organizer
  日本放射線影響学会
- Place of Presentation
  JMSアステールプラザ（広島県広島市））
- Year and Date
  2016-10-26
- Data Source
  KAKENHI-PROJECT-16K00541
[Presentation] メダカをモデルとした小児がん脳腫瘍放射線照射に伴う脳内免疫細胞ミクログリアの応答2016
- Author(s)
  保田隆子、五十嵐健人、浅香智美、永田健斗、鈴木芳代、横田裕一郎、尾田正二、舟山知夫、三谷啓志
- Organizer
  日本放射線腫瘍学会
- Place of Presentation
  国立京都国際会館（京都府京都市）
- Year and Date
  2016-11-25
- Data Source
  KAKENHI-PROJECT-16K00541
[Presentation] p53遺伝子欠損メダカ精巣における低線量率照射・分割照射後の組織変化2016
- Author(s)
  永田健斗、保田隆子、藤原智子、藤堂剛、尾田正二、三谷啓志
- Organizer
  日本放射線影響学会第59回大会
- Place of Presentation
  JMSアステールプラザ　（広島市）
- Year and Date
  2016-10-26
- Data Source
  KAKENHI-PROJECT-25220102
[Presentation] Embryonic medaka model unveiling efficient apoptotic cell clearance by specific microglial recruitment in response to irradiation2016
- Author(s)
  Takako Yasuda
- Organizer
  国際放射線神経生物学会大会
- Place of Presentation
  長崎大学良順会館(長崎、坂本）
- Year and Date
  2016-02-12
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25514002
[Presentation] p53タンパクは胞胚期の細胞損傷を修復し正常な形態形成を進行させるのに必須である2015
- Author(s)
  保田隆子、永田健斗、尾田正二、浅香智美、鈴木芳代、舟山知夫、小林泰彦、三谷啓志
- Organizer
  第38回日本分子生物学会
- Place of Presentation
  神戸国際会議場　（兵庫県神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-25220102
[Presentation] Efficient elimination of radiation-induced apoptotic cells by microglia during tissue repair in developing medaka brain2015
- Author(s)
  Takako Yasuda
- Organizer
  15th International Congress of Radiation Research
- Place of Presentation
  国立京都国際会館（京都府京都市）
- Year and Date
  2015-05-25
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25220102
[Presentation] Efficient elimination of radiation-induced apoptotic cells by microglia during tissue repair in developing medaka brain2015
- Author(s)
  Takako Yasuda
- Organizer
  ICRR京都国際学会
- Place of Presentation
  国立京都国際会館(京都、宝が池）
- Year and Date
  2015-05-25
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25514002
[Presentation] The recovering process of zonal differentiation in brain from radiation injury using a fish retina as a vertebrate brain model2015
- Author(s)
  Takako Yasuda, Kei Hirakawa, Shoji Oda, and Hiroshi Mitani
- Organizer
  ICRR京都国際学会
- Place of Presentation
  国立京都国際会館(京都、宝が池）
- Year and Date
  2015-05-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25514002
[Presentation] p53タンパクは胞胚期の細胞損傷を修復し正常な形態形成を進行させるのに必須である2015
- Author(s)
  保田隆子、永田健斗、尾田正二、浅香智美、鈴木芳代、舟山知夫、小林泰彦、三谷啓志
- Organizer
  日本分子生物学会
- Place of Presentation
  神戸ポートピアホテル（兵庫、神戸）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-25514002
[Presentation] メダカ胚網膜をモデルとした脳の層構造が傷害から修復する過程の解明2015
- Author(s)
  保田隆子、平川慶、尾田正二、三谷啓志
- Organizer
  日本動物学会
- Place of Presentation
  朱鷺メッセ（新潟、万代島）
- Year and Date
  2015-09-17
- Data Source
  KAKENHI-PROJECT-25514002
[Presentation] Microglial activation is regulated by independent two processes in irradiation-injured brain of medaka (Oryzias latipes)2013
- Author(s)
  Takako Yasuda, Shoji Oda, Yusuke Hibi, Satomi Satoh, Natsumaro Kutsuna and Hroshi Mitani
- Organizer
  小型魚類学会
- Place of Presentation
  宮城　仙台アエルビル
- Data Source
  KAKENHI-PROJECT-25514002
[Presentation] Up-regulation of ApolipoproteinE in microglia after phagocytotic activity is independent of the frequency of apoptotic neurons in damaged embryonic brain of medaka (Oryzias latipes) by irradiation2013
- Author(s)
  Takako Yasuda, Shoji Oda, Yusuke Hibi, Satomi Satoh, Natsumaro Kutsuna and Hroshi Mitani
- Organizer
  分子生物学会
- Place of Presentation
  兵庫　神戸ポートアイランド
- Data Source
  KAKENHI-PROJECT-25514002
[Presentation] 放射線による胚の神経細胞傷害を除去するミクログリアの活性化には二つの経路がある2013
- Author(s)
  保田隆子、尾田正二、佐藤聡海、三谷啓志
- Organizer
  日本放射線影響学会
- Place of Presentation
  青森　弘前ホテルクラウンパレス青森
- Data Source
  KAKENHI-PROJECT-25514002
[Presentation] メダカ胚の脳に対する重粒子線マイクロビーム照射応答解析2012
- Author(s)
  保田隆子、尾田正二、日比勇祐、三谷啓志、舟山知夫、横田裕一郎、武藤康子、池田裕子、小林泰彦
- Organizer
  第55回放射線影響学会
- Place of Presentation
  仙台
- Year and Date
  2012-09-06
- Data Source
  KAKENHI-PROJECT-22510056
[Presentation] メダカ胚の脳に対する重粒子線マイクロビーム照射応答解析2012
- Author(s)
  保田隆子、尾田正二、日比勇祐、三谷啓志、舟山知夫、横田裕一郎、武藤康子、池田裕子、小林泰彦
- Organizer
  アイソトープ研究会
- Place of Presentation
  東京大学
- Year and Date
  2012-07-09
- Data Source
  KAKENHI-PROJECT-22510056
[Presentation] メダカ胚の脳に対する重粒子炭素線マイクロビーム照射応答解析2012
- Author(s)
  保田隆子
- Organizer
  第55回　日本放射線影響学会
- Place of Presentation
  東北大学（仙台）
- Data Source
  KAKENHI-PROJECT-21221003
[Presentation] メダカ胚の脳に対する重粒子炭素線マイクロビーム照射応答解析2012
- Author(s)
  保田隆子
- Organizer
  放射線影響学会
- Place of Presentation
  東北大学川内北キャンパス
- Data Source
  KAKENHI-PROJECT-22510056
[Presentation] Imaging of microglial phagocytosis in the gamma-ray irradiated developing brain in vivo using p53(-/-) medaka(Oryzias latipes), a vertebrate model2011
- Author(s)
  Takako YASUDA, Yusuke HIBI, Shoji ODA, andHiroshi MITANI
- Organizer
  小型魚類学会
- Place of Presentation
  基生研
- Year and Date
  2011-09-08
- Data Source
  KAKENHI-PROJECT-22510056
[Presentation] Imaging of microglial phagocytosis in the gamma-ray irradiated developing brain in vivo using p53(-/-) medaka (Oryzias latipes), a vertebrate model2011
- Author(s)
  Takako YASUDA, Yusuke HIBI, Shoji ODA, Hiroshi MITANI
- Organizer
  第17回小型魚類研究会
- Place of Presentation
  東レ総合研修センター
- Year and Date
  2011-09-08
- Data Source
  KAKENHI-PROJECT-22510056
[Presentation] 放射線誘発細胞死のin vivoイメージング2011
- Author(s)
  日比勇祐、保田隆子、尾田正二、三谷啓志
- Organizer
  第54回放射線影響学会
- Place of Presentation
  神戸商工会議所
- Year and Date
  2011-11-18
- Data Source
  KAKENHI-PROJECT-22510056
[Presentation] メダカ胚を用いた放射線誘発アポトーシスの貪食in vivoイメージング2011
- Author(s)
  保田隆子、日比勇祐、水谷治央、平田愛子、尾田正二、三谷啓志
- Organizer
  第11回東京大学生命科学シンポジウム
- Place of Presentation
  東京大学安田講堂
- Year and Date
  2011-06-04
- Data Source
  KAKENHI-PROJECT-22510056
[Presentation] 放射線誘発細胞死のinvivoイメージング2011
- Author(s)
  日比勇祐、保田隆子、尾田正二、三谷啓志
- Organizer
  第54回放射線影響学会
- Place of Presentation
  神戸
- Year and Date
  2011-11-18
- Data Source
  KAKENHI-PROJECT-22510056
[Presentation] メダカ胚を用いた放射線誘発アポトーシスの貪食invivoイメージング2011
- Author(s)
  保田隆子、日比勇祐、水谷治央、平田愛子、尾田正二、三谷啓志
- Organizer
  第12回東京大学生命科学シンポジウム
- Year and Date
  2011-06-04
- Data Source
  KAKENHI-PROJECT-22510056
[Presentation] メダカ胚を用いた脳の放射線傷害時におけるミクログリア細胞3Dイメージング2011
- Author(s)
  保田隆子、日比勇祐、朽名夏麿、尾田正二、三谷啓志
- Organizer
  第54回放射線影響学会
- Place of Presentation
  神戸商工会議所
- Year and Date
  2011-11-18
- Data Source
  KAKENHI-PROJECT-22510056
[Presentation] メダカ胚を用いた脳の放射線傷害時におけるミクログリア細胞3Dイメージング2011
- Author(s)
  保田隆子、日比勇祐、朽名夏麿、尾田正二、三谷啓志
- Organizer
  第54回放射線影響学会
- Place of Presentation
  神戸
- Year and Date
  2011-11-18
- Data Source
  KAKENHI-PROJECT-22510056
[Presentation] P53(-/-)メダカ胚発生中の脳で起こる放射線誘発アポトーシス2010
- Author(s)
  保田隆子, ら
- Organizer
  第53回放射線影響学会
- Place of Presentation
  京都テルサ
- Year and Date
  2010-10-21
- Data Source
  KAKENHI-PROJECT-21221003
[Presentation] p53(-/-)メダカ胚発生中の脳で起こる放射線誘発アポトーシス2010
- Author(s)
  保田隆子、日比勇祐、尾田正二、三谷啓志
- Organizer
  第53回放射線影響学会
- Place of Presentation
  京都
- Year and Date
  2010-10-21
- Data Source
  KAKENHI-PROJECT-22510056
[Presentation] P53(-/-)メダカ胚発生中の脳で起こる放射線誘発アポトーシス2010
- Author(s)
  保田隆子
- Organizer
  第53回放射線影響学会
- Place of Presentation
  京都テルサ
- Year and Date
  2010-10-21
- Data Source
  KAKENHI-PROJECT-22510056
[Presentation] Medaka blastoderm cells can compensate for the injured cells by carbon-ion micro-beam irradiation
- Author(s)
  TakakoYasuda, Shoji Oda, Kento Nagata, Tomomi Watanabe-Asaka, Tomoo Funayama, Yuichiro Yokota, Michiyo Suzuki, Yasuhiko Kobayashi and Hiroshi Mitani
- Organizer
  小型魚類研究会
- Place of Presentation
  慶應義塾大学薬学部芝共立キャンパス(東京都港区)
- Year and Date
  2014-09-20 – 2014-09-21
- Data Source
  KAKENHI-PROJECT-25514002
[Presentation] 放射線により誘発されるp53遺伝子欠損メダカ精巣内の卵原幹細胞の分化と成長
- Author(s)
  西谷彩香、保田隆子、尾田正二、三谷啓志
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド（兵庫県神戸市）
- Year and Date
  2013-12-03 – 2013-12-06
- Data Source
  KAKENHI-PROJECT-21221003
[Presentation] メダカ胚の脳に対する重粒子線マイクロビーム照射応答解析
- Author(s)
  保田隆子
- Organizer
  アイソトープ研究会
- Place of Presentation
  東京大学農学部
- Data Source
  KAKENHI-PROJECT-22510056
[Presentation] 放射線による胚の神経細胞傷害を除去するミクログリアの活性化には二つの経路がある
- Author(s)
  保田隆子、尾田正二、佐藤聡海、三谷啓志
- Organizer
  日本放射線影響学会第56回大会
- Place of Presentation
  ホテルクラウンパレス青森（青森青森県青森市）
- Year and Date
  2013-10-18 – 2013-10-20
- Data Source
  KAKENHI-PROJECT-21221003
[Presentation] The pivotal role of the p53 gene in the elimination of spontaneous testis-ova in medaka testes.
- Author(s)
  Yasuda T., Li Z., Urushihara Y., Suzuki Y., Oda S. and Mitani H
- Organizer
  8th European Zebrafish Meeting
- Place of Presentation
  Barcelona, Spain
- Year and Date
  2013-07-09 – 2013-07-13
- Data Source
  KAKENHI-PROJECT-21221003
[Presentation] Investigation of somatic acute responses induced by local irradiation in adult medaka
- Author(s)
  Chika Hashimoto, Tomomi Watanabe-Asaka, Takako Yasuda, Hisako Oonishi, Toshiyuki Nishimaki, Takafumi Katsumura, Hiroki Oota, Hiroko Ikeda, Yuichiro Yokota, Michiyo Suzuki, Tomoo Funayama, Yasuhiko Kobayashi, Shoji Oda, and Hiroshi Mitani.
- Organizer
  The 20th Japanese Medaka and Zebrafish Meeting
- Place of Presentation
  慶応大学薬学部芝共立キャンパス（東京都港区）
- Year and Date
  2014-09-20 – 2014-09-21
- Data Source
  KAKENHI-PROJECT-25220102
[Presentation] メダカ胚を用いた眼で起こる放射線誘発アポトーシスとそれらの修復
- Author(s)
  保田隆子、平川慶、尾田正二、三谷啓志
- Organizer
  放射線影響学会
- Place of Presentation
  かごしま県民交流センター(鹿児島県鹿児島市)
- Year and Date
  2014-10-01 – 2014-10-03
- Data Source
  KAKENHI-PROJECT-25514002

1. MITANI Hiroshi (70181922)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
2. NODA Asao (40294227)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. ODA Shoji (50266714)

# of Collaborated Projects: 2 results

# of Collaborated Products: 14 results
4. FUJIWARA Tomoko (70402922)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. TAKANO Yoshiro (90126425)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. ASAKA Tomomi (90555707)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
7. Funayama Tomoo (40354956)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
8. Kutsuna Natsumaro (70578559)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
9. 立花章 (20188262)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 濱崎幹也 (80443597)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 藤堂剛 (90163948)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. 山本卓 (90244102)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 漆原祐介

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 村田泰彦

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 五十嵐健人

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 張添翼

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 大西壽子

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 塩谷典子

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 伊藤加津沙

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 西谷彩香

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
21. 平川慶

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 永田健斗

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 橋本知佳

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. ISHIKAWA Tomoko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Yasuda Takako 保田 隆子

保田 隆子 ヤスダ タカコ

YASUDA Takako 保田 隆子

Research Projects

Research Products

Co-Researchers

A trial to regulate microglial activation in medaka embryo as a model to avoid cytokine stormPrincipal Investigator

Principal Investigator

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Review Section

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Live imaging for activated microglia in response to radiation-induced brain injury by utilizing transgenic medakaPrincipal Investigator

Principal Investigator

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Embryonic medaka model of microglia in the developing CNS allowing in vivo analysis of their spatiotemporal recruitment in response to cosmic radiationPrincipal Investigator

Principal Investigator

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Research Institution

In vivo, in situ assessment of the mutagenic risk of radiation and environmental chemicals, using newly developed animal systems

Principal Investigator

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Research Institution

microglial behavior in irradiation-injured developing brain using medaka, a vertebrate modelPrincipal Investigator

Principal Investigator

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Research Institution

Visualization of radiation induced mutagenesis in vivo

Principal Investigator

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[Journal Article] 3D reconstructed brain images reveal the possibility of the ogg1 gene to suppress the irradiation-induced apoptosis in embryonic brain in medaka (Oryzias latipes)2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Radical change of apoptotic strategy following irradiation during later period of embryogenesis in medaka (Oryzias latipes)2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] メダカ胚で明らかになった放射線により活性化された脳内免疫細胞ミクログリアの動態2018

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Abscopal Activation of Microglia in Embryonic Fish Brain Following Targeted Irradiation with Heavy-Ion Microbeam.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] In vivo 3D analysis of systemic effects after local heavy-ion beam irradiation in an animal model2016

Author(s)

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DOI

Data Source

[Journal Article] Irradiation-injured brain tissues normally self-renewed in the absence of p53, the pivotal tumor suppressor, in medaka (Oryzias latipes) embryo.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Embryonic medaka model of microglia in the developing CNS allowing in vivo analysis of their spatiotemporal recruitment in response to irradiation2015

Author(s)

Journal Title

Data Source

[Journal Article] Embryonic medaka model of microglia in the developing CNS allowing in vivo analysis of their spatiotemporal recruitment in response to irradiation.2015

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Journal Title

Data Source

Yasuda Takako 保田隆子

保田隆子ヤスダタカコ

YASUDA Takako 保田隆子