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ISODA Ryutaro  磯田 竜太朗

ORCIDConnect your ORCID iD *help
Researcher Number 40456942
Affiliation (based on the past Project Information) *help 2014: 独立行政法人国立長寿医療研究センター, その他部局等, その他
2013: 独立行政法人国立長寿医療研究センター, 口腔疾患研究部, 流動研究員
2008 – 2010: Osaka University, 大学院・歯学研究科, 特任研究員
Review Section/Research Field
Principal Investigator
Morphological basic dentistry
Except Principal Investigator
Periodontology / Morphological basic dentistry
Keywords
Principal Investigator
歯周病原性細菌 / 免疫寛容 / 粘膜免疫 / 常在細菌 / 動物モデル / 歯周炎 / 口腔細菌学
Except Principal Investigator
一酸化窒素 / 感染制御 / 肺炎 … More / 低分子量Gタンパク質 / 細菌感染 / s-ニトロシル化 / 自然免疫 / マクロファージ / 歯周病原細菌 / 歯周病 / ファゴサイトーシス / Rab5 / 活性酸素 / 酸化修飾 / 核酸 / 免疫学 / 微生物 / 細菌 / 感染症 Less
  • Research Projects

    (3 results)
  • Research Products

    (24 results)
  • Co-Researchers

    (6 People)
  •  Correlation between oxidative modified protein and pathogenesis of periodontal disease

    • Principal Investigator
      MATSUSHITA Kenji
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Periodontology
    • Research Institution
      National Center for Geriatrics and Gerontology
  •  レンサ球菌のmicroRNAがヒト組織に及ぼす病原性のオーソログ検索

    • Principal Investigator
      寺尾 豊
    • Project Period (FY)
      2009 – 2010
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Osaka University
  •  Evaluation of immune regulation against oral commensal bacteria and its impact on host protection against infection.Principal Investigator

    • Principal Investigator
      ISODA Ryutaro
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Osaka University

All 2015 2014 2013 2011 2010 2009 Other

All Journal Article Presentation Book

  • [Book] Chapter 26. Periodontal disease as a possible risk factor for Alzheimer’s disease, in Innovative Research on Biosis-Abiosis Intelligent Interface 20142015

    • Author(s)
      Ishida N, Ishihara Y, Ishida K, Tada H, Kato Y, Isoda R, Hagiwara M, Michikawa M, Noguchi T, and Matsushita K
    • Total Pages
      8
    • Publisher
      Springer Japan
    • Data Source
      KAKENHI-PROJECT-25670888
  • [Book] The role of Protein Oxidative Modification in Periodontal Diseases, in Studies on Periodontal Disease2014

    • Author(s)
      Isoda R and Matsushita K
    • Total Pages
      18
    • Publisher
      Springer New York
    • Data Source
      KAKENHI-PROJECT-25670888
  • [Book] The role of Protein Oxidative Modification in Periodontal Diseases, in Studies on Periodontal Disease.2014

    • Author(s)
      Isoda R and Matsushita K
    • Total Pages
      18
    • Publisher
      Springer New York
    • Data Source
      KAKENHI-PROJECT-25670888
  • [Journal Article] TNF-α augmented Porphyromonas gingivalis invasion in human gingival epithelial cells through Rab5 and ICAM-1.2014

    • Author(s)
      Kato Y, Hagiwara M, Ishihara Y, Isoda R, Sugiura S, Komatsu T, Ishida N, Noguchi T and Matsushita K
    • Journal Title

      BMC Microbiology

      Volume: 14 Issue: 1 Pages: 229-229

    • DOI

      10.1186/s12866-014-0229-z

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25670888, KAKENHI-PROJECT-25862066, KAKENHI-PROJECT-26293438, KAKENHI-PROJECT-26861586
  • [Journal Article] Vinculin and Rab5 complex is requited for uptake of Staphyrococcus aure us and interleukin-6 expression.2014

    • Author(s)
      Hagiwara M, Kokubu E, Sugiura S, Komatsu T, Tada H, Isoda R, Tanigawa N, Kato Y, Ishida N, Kobayashi K, Nakashima M, Ishihara K, Matsushita K.
    • Journal Title

      PLoS One

      Volume: 9 Issue: 1 Pages: e87373-e87373

    • DOI

      10.1371/journal.pone.0087373

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-11J09815, KAKENHI-PROJECT-24592778, KAKENHI-PROJECT-25463225, KAKENHI-PROJECT-25670888, KAKENHI-PROJECT-25862066, KAKENHI-PROJECT-26293438
  • [Journal Article] POT1b regulates phagocytosis and NO production by modulating activity of the small GTPase Rab5.2013

    • Author(s)
      Hagiwara M, Komatsu T, Sugiura S, Isoda R, Tada H, Tanigawa N, Kato Y, Ishida N, Kobayashi K, and Matsushita K
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 439 Issue: 3 Pages: 413-417

    • DOI

      10.1016/j.bbrc.2013.08.018

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-11J09815, KAKENHI-PROJECT-25463225, KAKENHI-PROJECT-25670888, KAKENHI-PROJECT-25862066
  • [Journal Article] Pili of oral Streptococcus sanguinis bind to salivary amylase and promote the biofilm formation2011

    • Author(s)
      Okahashi, N., Nakata M., Sakurai A., Terao Y., Hoshino T., Yamaguchi Y., Isoda R., Sumitomo T., Nakano K., Kawabata S., Ooshima T.
    • Journal Title

      Microbial Pathogenesis

      Volume: 50 Pages: 148-154

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21659423
  • [Journal Article] Pili of oral Streptococcus sanguinis bind to fibronectin and contribute to cell adhesion.2010

    • Author(s)
      Okahashi N, M.Nakata, A.Sakurai, Y.Terao, T.Hoshino, M.Yamaguchi, R.Isoda, T.Sumitomo, K.Nakano, S.Kawabata, T.Ooshima.
    • Journal Title

      Biochem.Biophys.Res.Commun. 391(2)

      Pages: 1192-1196

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21659423
  • [Journal Article] Nrc of Streptococeus pneumoniae suppresses capsule expression and enhances anti-phagocytosis.2009

    • Author(s)
      Yamaguchi, M., Y.Minamide, Y.Terao, R.Isoda, T.Ogawa, S.Yokota, S.Hamada, S.Kawabata.
    • Journal Title

      Biochem.Biophys.Res.Commun. 390(1)

      Pages: 155-160

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21659423
  • [Journal Article] Molecular and biological characterization of novel gtf regulation-associated genes in Streptococcus mutans.2009

    • Author(s)
      Terao, Y., R.Isoda, J.Murakami, S.Hamada, S.Kawabata.
    • Journal Title

      Oral Microbiol.Immunol. 24(3)

      Pages: 211-217

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21659423
  • [Presentation] M6型A群レンサ球菌が産生する線毛形成機構と機能解析2010

    • Author(s)
      木村敬次リチャード, 住友倫子, 寺尾豊, 磯田竜太朗, 中田匡宣, 川端重忠
    • Organizer
      第63回日本細菌学会 関西支部総会
    • Place of Presentation
      枚方市
    • Year and Date
      2010-11-20
    • Data Source
      KAKENHI-PROJECT-21659423
  • [Presentation] M6型A群レンサ球菌が産生する線毛形成機構と機能解析2010

    • Author(s)
      木村敬次リチャード, 住友倫子, 寺尾豊, 磯田竜太朗, 中田匡宣, 川端重忠
    • Organizer
      第63回日本細菌学会 関西支部総会
    • Place of Presentation
      枚方市
    • Year and Date
      2010-11-20
    • Data Source
      KAKENHI-PROJECT-20592137
  • [Presentation] A群レンサ球菌が産生する線毛の細胞壁架橋機構の解析2010

    • Author(s)
      中田匡宣, 住友倫子, 磯田竜太朗, 寺尾豊, 川端重忠
    • Organizer
      第83回日本細菌学会総大会
    • Place of Presentation
      横浜市
    • Data Source
      KAKENHI-PROJECT-21659423
  • [Presentation] Neonatal Exposure Induced Commensal-like Immune-response Against Aggregatibacter actinomycetemcomitans in Mice2009

    • Author(s)
      R.ISODA, Y.TERAO, M.NAKATA, T.SUMITOMO, S.KAWABATA
    • Organizer
      87^<th> International Association for Dental Research General Session
    • Place of Presentation
      Miami, USA
    • Year and Date
      2009-04-04
    • Data Source
      KAKENHI-PROJECT-20592137
  • [Presentation] ファゴサイトーシスにおける一酸化窒素の役割

    • Author(s)
      萩原真、磯田竜太朗、加藤佳子、石田直之、小林かおる、松下健二
    • Organizer
      第36回日本分生生物学会大会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-25670888
  • [Presentation] アルツハイマー病と歯周病との関連性に関する研究

    • Author(s)
      石田直之, 加藤佳子, 磯田竜太朗, 多田浩之, 石田和人, 石原裕一, 道川 誠, 野口俊英, 松下健二
    • Organizer
      第55回春季日本歯周病学会学術大会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-25670888
  • [Presentation] vinculinとRab5によるStaphylococcus aureusの細胞内移行メカニズムの解析

    • Author(s)
      萩原真、国分栄仁、杉浦進介、小松寿明、多田浩之、磯田竜太朗、谷川順美、加藤佳子、石田直之、小林かおる、石原和幸、松下健二
    • Organizer
      第8回トランスポーター研究会年会
    • Place of Presentation
      熊本
    • Data Source
      KAKENHI-PROJECT-25670888
  • [Presentation] 細菌が細胞内へ侵入する時の一酸化窒素の役割とそれを制御する食品由来因子の探索

    • Author(s)
      萩原真、磯田竜太朗、加藤佳子、石田直之、小林かおる、松下健二
    • Organizer
      第67回日本栄養食糧学会大会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-25670888
  • [Presentation] Effect of Nitric Oxide on phagocytosis

    • Author(s)
      Hagiwara M, Isoda R, Kato Y, Ishida N, Wang J, Matsushita K
    • Organizer
      名古屋グローバルリトリート
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-25670888
  • [Presentation] 一酸化窒素によるRab5依存性エンドサイトーシス制御機構の解明

    • Author(s)
      萩原真、磯田竜太朗、加藤佳子、石田直之、小林かおる、松下健二
    • Organizer
      第86回日本生化学会大会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-25670888
  • [Presentation] Rab5 and ICAM-1 mediate TNF-α augmented Porhyromonas ginigvalis invasion in cells.

    • Author(s)
      Kato Y, Hagiwara M, Ishihara Y, Isoda R, Sugiura S, Ishida N, Noguchi T and Matsushita K
    • Organizer
      The 2nd Meeting of the International Association for Dental Research-Asia Pacific Region
    • Place of Presentation
      Bangkok,Thailand
    • Data Source
      KAKENHI-PROJECT-25670888
  • [Presentation] Periodontitis Induced by Bacterial Infection Exacerbates Features of Alzheimer's disease in Transgenic Mice.

    • Author(s)
      Ishida N, Ishihara Y, Ishida K, Tada H, Kato Y, Isoda R, Hagiwara M, Michikawa M, Noguchi T, Matsushita K
    • Organizer
      The 5th International Symposium for Interface Oral Health Science
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-25670888
  • [Presentation] Periodontitis Induced by Bacterial Infection Exacerbates Features of Alzheimer's disease in Transgenic Mice.

    • Author(s)
      Ishida N, Ishihara Y, Ishida K, Tada H, Kato Y, Isoda R, Hagiwara M, Michikawa M, Noguchi N, Matsushita K
    • Organizer
      Alzheimer's Association International Conference 2013
    • Place of Presentation
      Boston,USA
    • Data Source
      KAKENHI-PROJECT-25670888
  • [Presentation] Vinculin: a Novel Rab5-binding Protein Required for Internalization of Staphyrococcus aureus to Nonphagocytic Cells.

    • Author(s)
      Hagiwara M, Kokubu E, Sugiura S, Komatsu T, Tada H, Isoda R, Tanigawa N, Kato Y, Ishida N, Kobayashi K, Jingshu W, Nakashima M, Ishihara K, and Matsushita K
    • Organizer
      The 5th International Symposium for Interface Oral Health Science
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-25670888
  • 1.  KAWABATA Shigetada (50273694)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 8 results
  • 2.  TERAO Yutaka (50397717)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 8 results
  • 3.  MATSUSHITA Kenji (90253898)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 14 results
  • 4.  HAGIWARA Makoto (30546099)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 11 results
  • 5.  TADA Hiroyuki (70431632)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 6.  中田 匡宣 (90444497)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results

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