SAITO Yasuyuki 齊藤泰之

Researcher Number	40508842
Other IDs	https://orcid.org/0000-0002-9291-1383
Affiliation (Current)	2025: 島根大学, 学術研究院医学・看護学系, 教授
Affiliation (based on the past Project Information) *help	2024: 島根大学, 学術研究院医学・看護学系, 教授 2016 – 2023: 神戸大学, 医学研究科, 講師 2016: 神戸大学, 大学院医学研究科, 講師 2015: 神戸大学, 医学(系)研究科(研究院), 講師 2008 – 2010: Gunma University, 生体調節研究所, 助教 2009: 群馬大, 生体調節研究所, 助教
Review Section/Research Field	Principal Investigator 膠原病・アレルギー・感染症内科学 / Basic Section 54010:Hematology and medical oncology-related / Medium-sized Section 50:Oncology and related fields / Basic Section 49070:Immunology-related / Immunology Except Principal Investigator Functional biochemistry
Keywords	Principal Investigator CD47 / SIRPα / 樹状細胞 / 自己免疫疾患 / ストローマ細胞 / 免疫学 / がん免疫 / 細胞死 / T細胞 / マクロファージ … More / がん微小環境 / ヒト化マウス / PDXモデル / 自己免疫性疾患 / 細胞・組織 / シグナル伝達 / 内科 / ヘルパーT細胞 / 接触過敏性皮膚炎 / モノクローナル抗体 / SHPS-1 … More Except Principal Investigator 癌 / 免疫学 / 脳・神経 / 生体分子 / シグナル伝達 Less

Molecular basis for the regulation of dendritic ell and mature T cell survivalPrincipal Investigator
- Principal Investigator
  
  Saito Yasuyuki
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Shimane University
  Kobe University
Development of a novel lymphoma PDX model using humanized micePrincipal Investigator
- Principal Investigator
  
  Saito Yasuyuki
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 50:Oncology and related fields
- Research Institution
  Kobe University
Regulation of dendritic cells and lymphoid tissues by CD47-SIRPalpha signalingPrincipal Investigator
- Principal Investigator
  
  Saito Yasuyuki
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 49070:Immunology-related
- Research Institution
  Kobe University
Regulation of the immunological function by the CD47-SIRP alpha signaling systemPrincipal Investigator
- Principal Investigator
  
  Saito Yasuyuki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  Kobe University
Molecular basis of the CD47-SIRP alpha signaling system in the regulation of physiological function
- Principal Investigator
  
  Matozaki Takashi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  Kobe University
The role of SHPS-1 in dendritic cell-mediated autoimmune diseasesPrincipal Investigator
- Principal Investigator
  
  SAITO Yasuyuki
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  Gunma University
CD47ーSHPSー1系による自己免疫疾患の新たな制御メカニズムの解明Principal Investigator
- Principal Investigator
  
  齊藤泰之
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (Start-up)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  Gunma University

[Book] Encyclopedia of Signaling Molecules: Sirpa2017
- Author(s)
  Yasuyuki Saito, Yoji Murata, Takenori Kotani, Takashi Matozaki
- Total Pages
  7
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-15K08532
[Book] Encyclopedia of Signaling Molecules: PTPRH2017
- Author(s)
  Yoji Murata, Takenori Kotani, Yasuyuki Saito, Takashi Matozaki
- Total Pages
  8
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-15K08532
[Book] Encyclopedia of Signaling Molecules: Tyrosine-Protein Phosphatase Nonreceptor Type 11 (PTPN11)2017
- Author(s)
  Takenori Kotani, Yoji Murata, Yasuyuki Saito, Takashi Matozaki
- Total Pages
  9
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-15K08532
[Journal Article] Utility of the refined EBMT diagnostic and severity criteria 2023 for sinusoidal obstruction syndrome/veno-occlusive disease2024
- Author(s)
  Ichikawa H, Yakushijin K, Kurata K, Tsuji T, Takemoto N, Joyce M, Okazoe Y, Takahashi R, Matsumoto S, Sakai R, Kitao A, Miyata Y, Saito Y, Kawamoto S, Yamamoto K, Ito M, Murayama T, Matsuoka H, Minami H
- Journal Title
  
  Bone Marrow Transplantation
  
  Volume: 59 Issue: 4 Pages: 518-525
- DOI
  10.1038/s41409-024-02215-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08504, KAKENHI-PROJECT-24K10553
[Journal Article] Editorial: The therapeutic inhibition of macrophage checkpoints2024
- Author(s)
  Theocharides APA, Hutter G, Saito Y.
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 15 Pages: 1418281-1418281
- DOI
  10.3389/fimmu.2024.1418281
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08504
[Journal Article] Enhancing anti-EGFRvIII CAR T cell therapy against glioblastoma with a paracrine SIRPγ-derived CD47 blocker2024
- Author(s)
  Martins TA, Kaymak D, Tatari N, Gerster F, Hogan S, Ritz MF, Sabatino V, Wieboldt R, Bartoszek EM, McDaid M, Gerber A, Buck A, Beshirova A, Heider A, Shekarian T, Mohamed H, Etter MM, Schmassmann P, Abel I, Boulay JL, Saito Y, Mariani L, Guzman R, Snijder B, Weiss T, Laubli H, Hutter G.
- Journal Title
  
  Nature Communications
  
  Volume: 15 Issue: 1 Pages: 9718-9718
- DOI
  10.1038/s41467-024-54129-w
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08504
[Journal Article] Analysis of B‐cell receptor repertoire to evaluate immunogenicity of monovalent Omicron XBB.1.5 mRNA vaccines2024
- Author(s)
  Funakoshi Y, Yakushijin K, Ohji G, Matsutani T, Doi K, Sakai H, Sasaki T, Kusakabe T, Matsumoto S, Saito Y, Kawamoto S, Yamamoto K, Koyama T, Nagatani Y, Kurata K, Kimbara S, Imamura Y, Kiyota N, Ito M, Minami H.
- Journal Title
  
  eJHaem
  
  Volume: 5 Issue: 4 Pages: 661-668
- DOI
  10.1002/jha2.932
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08504, KAKENHI-PROJECT-24K10553
[Journal Article] Preclinical evaluation of the efficacy of an antibody to human SIRPα for cancer immunotherapy in humanized mouse models2023
- Author(s)
  Saito Yasuyuki、Iida-Norita Rie、Afroj Tania、Refaat Alaa、Hazama Daisuke、Komori Satomi、Ohata Shinya、Takai Tomoko、Oduori Okechi S.、Kotani Takenori、Funakoshi Yohei、Koma Yu-Ichiro、Murata Yoji、Yakushijin Kimikazu、Matsuoka Hiroshi、Minami Hironobu、Yokozaki Hiroshi、Manz Markus G.、Matozaki Takashi
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 14 Pages: 1294814-1294814
- DOI
  10.3389/fimmu.2023.1294814
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06926, KAKENHI-PROJECT-22K08504, KAKENHI-PROJECT-22K19458, KAKENHI-PROJECT-22K15494, KAKENHI-PROJECT-22K16302, KAKENHI-PROJECT-22KF0254, KAKENHI-PROJECT-21H04807
[Journal Article] Early diagnosis of sinusoidal obstruction syndrome after hematopoietic stem cell transplantation, with modified diagnostic criteria including refractory thrombocytopenia2023
- Author(s)
  Ichikawa H, Yakushijin K, Miyata Y, Kanehira H, Joyce M, Hirakawa Y, Matsumoto S, Nagao S, Sakai R, Kurata K, Kitao A, Saito Y, Kawamoto S, Yamamoto K, Ito M, Murayama T, Matsuoka H, Minami H
- Journal Title
  
  eJHaem
  
  Volume: 4 Issue: 3 Pages: 695-704
- DOI
  10.1002/jha2.728
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08504
[Journal Article] Response to mRNA SARS‐CoV‐2 vaccination evaluated by B‐cell receptor repertoire after tixagevimab/cilgavimab administration2023
- Author(s)
  Funakoshi Y, Yakushijin K, Ohji G, Matsutani T, Hojo W, Sakai H, Matsumoto S, Watanabe M, Kitao A, Saito Y, Kawamoto S, Yamamoto K, Koyama T, Nagatani Y, Kimbara S, Imamura Y, Kiyota N, Ito M, Minami H
- Journal Title
  
  British Journal of Haematology
  
  Volume: 202 Issue: 3 Pages: 504-516
- DOI
  10.1111/bjh.18932
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K08504
[Journal Article] Lysosomal cholesterol overload in macrophages promotes liver fibrosis in a mouse model of NASH2023
- Author(s)
  Itoh Michiko、Tamura Atsushi、Kanai Sayaka、Tanaka Miyako、Kanamori Yohei、Shirakawa Ibuki、Ito Ayaka、Oka Yasuyoshi、Hidaka Isao、Takami Taro、Honda Yasushi、Maeda Mitsuyo、Saito Yasuyuki、Murata Yoji、Matozaki Takashi、Nakajima Atsushi、Kataoka Yosky、Ogi Tomoo、Ogawa Yoshihiro、Suganami Takayoshi
- Journal Title
  
  Journal of Experimental Medicine
  
  Volume: 220 Issue: 11
- DOI
  10.1084/jem.20220681
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19524, KAKENHI-PROJECT-22K08504, KAKENHI-PROJECT-22K08667, KAKENHI-PROJECT-22K11700, KAKENHI-PROJECT-21K08526, KAKENHI-PROJECT-22K19458, KAKENHI-PROJECT-19KK0249, KAKENHI-PROJECT-20H00629, KAKENHI-PUBLICLY-22H04806, KAKENHI-PUBLICLY-23H04776, KAKENHI-PROJECT-21H04807, KAKENHI-PROJECT-23K27377
[Journal Article] CD47 promotes peripheral T cell survival by preventing dendritic cell?mediated T cell necroptosis2023
- Author(s)
  Komori Satomi、Saito Yasuyuki、Nishimura Taichi、Respatika Datu、Endoh Hiromi、Yoshida Hiroki、Sugihara Risa、Iida-Norita Rie、Afroj Tania、Takai Tomoko、Oduori Okechi S.、Nitta Eriko、Kotani Takenori、Murata Yoji、Kaneko Yoriaki、Nitta Ryo、Ohnishi Hiroshi、Matozaki Takashi
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 120 Issue: 33 Pages: 1-1
- DOI
  10.1073/pnas.2304943120
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06926, KAKENHI-PROJECT-22K08504, KAKENHI-PROJECT-21K08416, KAKENHI-PROJECT-22K19458, KAKENHI-PROJECT-22K15494, KAKENHI-PROJECT-22K16302, KAKENHI-PROJECT-22KF0254, KAKENHI-PLANNED-21H05254, KAKENHI-PROJECT-21H04807, KAKENHI-PROJECT-23K24057
[Journal Article] Targeting of SIRPα as a potential therapy for Langerhans cell histiocytosis2023
- Author(s)
  Okamoto Takeshi、Murata Yoji、Hasegawa Daiichiro、Yoshida Makiko、Tanaka Daisuke、Ueda Takashi、Hazama Daisuke、Oduori Okechi S.、Komori Satomi、Takai Tomoko、Saito Yasuyuki、Kotani Takenori、Kosaka Yoshiyuki、Maniwa Yoshimasa、Matozaki Takashi
- Journal Title
  
  Cancer Science
  
  Volume: - Issue: 5 Pages: 1871-1881
- DOI
  10.1111/cas.15758
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06926, KAKENHI-PROJECT-22KF0254, KAKENHI-PROJECT-22K08504, KAKENHI-PROJECT-22K19458, KAKENHI-PROJECT-22K15494, KAKENHI-PROJECT-21H04807
[Journal Article] The Safety and Immunogenicity of the BNT162b2 mRNA COVID-19 Vaccine in Japanese Patients after Allogeneic Stem Cell Transplantation2022
- Author(s)
  Watanabe M, Yakushijin K, Funakoshi Y, Ohji G, Hojo W, Sakai H, Saeki M, Hirakawa Y, Matsumoto S, Sakai R, Nagao S, Kitao A, Miyata Y, Koyama T, Saito Y, Kawamoto S, Ito M, Murayama T, Matsuoka H, Minami H.
- Journal Title
  
  Vaccines
  
  Volume: 10 Issue: 2 Pages: 158-158
- DOI
  10.3390/vaccines10020158
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07782, KAKENHI-PROJECT-22K08504
[Journal Article] Global longitudinal strain is superior to ejection fraction for long‐term follow‐up after allogeneic hematopoietic stem cell transplantation2022
- Author(s)
  Watanabe M, Yakushijin K, Tanaka H, Chijiki R, Saeki M, Hirakawa Y, Takakura H, Usui Y, Ichikawa H, Sakai R, Matsumoto S, Nagao S, Mizutani Y, Kurata K, Kitao A, Miyata Y, Saito Y, Kawamoto S, Yamamoto K, Ito M, Matsuoka H, Minami H
- Journal Title
  
  eJHaem
  
  Volume: 4 Issue: 1 Pages: 192-198
- DOI
  10.1002/jha2.586
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08504, KAKENHI-PROJECT-20K07782
[Journal Article] A Third Dose COVID-19 Vaccination in Allogeneic Hematopoietic Stem Cell Transplantation Patients2022
- Author(s)
  Watanabe M, Yakushijin K, Funakoshi Y, Ohji G, Ichikawa H, Sakai H, Hojo W, Saeki M, Hirakawa Y, Matsumoto S, Sakai R, Nagao S, Kitao A, Miyata Y, Koyama T, Saito Y, Kawamoto S, Yamamoto K, Ito M, Murayama T, Matsuoka H, Minami H
- Journal Title
  
  Vaccines
  
  Volume: 10 Issue: 11 Pages: 1830-1830
- DOI
  10.3390/vaccines10111830
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08504, KAKENHI-PROJECT-20K07782
[Journal Article] Promising Efficacy of a Third Dose of mRNA SARS-CoV-2 Vaccination in Patients Treated with Anti-CD20 Antibody Who Failed 2-Dose Vaccination2022
- Author(s)
  Funakoshi Y, Yakushijin K, Ohji G, Hojo W, Sakai H, Watanabe M, Kitao A, Miyata Y, Saito Y, Kawamoto S, Yamamoto K, Ito M, Koyama T, Imamura Y, Kiyota N, Matsuoka H, Mori Y, Minami H
- Journal Title
  
  Vaccines
  
  Volume: 10 Issue: 6 Pages: 965-965
- DOI
  10.3390/vaccines10060965
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08504, KAKENHI-PROJECT-20K07782
[Journal Article] The Role of Type-2 Conventional Dendritic Cells in the Regulation of Tumor Immunity2022
- Author(s)
  Saito Yasuyuki、Komori Satomi、Kotani Takenori、Murata Yoji、Matozaki Takashi
- Journal Title
  
  Cancers
  
  Volume: 14 Issue: 8 Pages: 1976-1976
- DOI
  10.3390/cancers14081976
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06926, KAKENHI-PROJECT-22K08504, KAKENHI-PROJECT-22K19458, KAKENHI-PROJECT-22K15494, KAKENHI-PROJECT-21H04807
[Journal Article] Anticancer efficacy of monotherapy with antibodies to SIRPα/SIRPβ1 mediated by induction of antitumorigenic macrophages2021
- Author(s)
  Sakamoto Mariko、Murata Yoji、Tanaka Daisuke、Kakuchi Yuka、Okamoto Takeshi、Hazama Daisuke、Saito Yasuyuki、Kotani Takenori、Ohnishi Hiroshi、Miyasaka Masayuki、Fujisawa Masato、Matozaki Takashi
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 119 Issue: 1
- DOI
  10.1073/pnas.2109923118
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07385, KAKENHI-PROJECT-20K21547, KAKENHI-PROJECT-21H04807
[Journal Article] Editorial: Advances in Human Immune System Mouse Models for Studying Human Hematopoiesis and Cancer Immunotherapy2021
- Author(s)
  Saito Yasuyuki、Willinger Tim、Theocharides Alexandre P. A.
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 12 Pages: 829644-829644
- DOI
  10.3389/fimmu.2021.829644
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21547
[Journal Article] Tetrameric glycoprotein complex gH/gL/gQ1/gQ2 is a promising vaccine candidate for human herpesvirus 6B2020
- Author(s)
  Wang Bochao、Hara Kouichi、Kawabata Akiko、Nishimura Mitsuhiro、Wakata Aika、Tjan Lidya Handayani、Poetranto Anna Lystia、Yamamoto Chisato、Haseda Yasunari、Aoshi Taiki、Munakata Lisa、Suzuki Ryo、Komatsu Masato、Tsukamoto Ryuko、Itoh Tomoo、Nishigori Chikako、Saito Yasuyuki、Matozaki Takashi、Mori Yasuko
- Journal Title
  
  PLOS Pathogens
  
  Volume: 16 Issue: 7 Pages: e1008609-e1008609
- DOI
  10.1371/journal.ppat.1008609
- NAID
  120006940234
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21547, KAKENHI-PROJECT-18H04032
[Journal Article] SIRPα on Mouse B1 Cells Restricts Lymphoid Tissue Migration and Natural Antibody Production2020
- Author(s)
  Franke Katka、Pillai Saravanan、Hoogenboezem Mark、Gijbels Marion、Matlung Hanke、Geissler Judy、Olsman Hugo、Pottgens Chantal、van Gorp Patrick、Ozsvar-Kozma Maria、Saito Yasuyuki、Matozaki Takashi、Kuijpers Taco、Hendriks Rudi、Kraal Georg、Binder Christoph、de Winther Menno、van den Berg Timo
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 11 Pages: 570963-570963
- DOI
  10.3389/fimmu.2020.570963
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21547, KAKENHI-PROJECT-18H04032
[Journal Article] Macrocyclic Peptide-Mediated Blockade of the CD47-SIRPα Interaction as a Potential Cancer Immunotherapy2020
- Author(s)
  Hazama Daisuke、Yin Yizhen、Murata Yoji、Matsuda Makoto、Okamoto Takeshi、Tanaka Daisuke、Terasaka Naohiro、Zhao Jinxuan、Sakamoto Mariko、Kakuchi Yuka、Saito Yasuyuki、Kotani Takenori、Nishimura Yoshihiro、Nakagawa Atsushi、Suga Hiroaki、Matozaki Takashi
- Journal Title
  
  Cell Chemical Biology
  
  Volume: 27 Issue: 9 Pages: 1181-1191.e7
- DOI
  10.1016/j.chembiol.2020.06.008
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07385, KAKENHI-PROJECT-20K21547, KAKENHI-PROJECT-20H05618, KAKENHI-PROJECT-18H04032
[Journal Article] BRAFV600E or mutant MAP2K1 human CD34+ cells establish Langerhans cell?like histiocytosis in immune-deficient mice2020
- Author(s)
  Rafiei Anahita、Wilk C. Matthias、Helbling Patrick M.、Myburgh Renier、Saito Yasuyuki、Haralambieva Eugenia、Soldini Davide、Chakraborty Rikhia、Merad Miriam、Allen Carl E.、Nombela-Arrieta Cesar、Manz Markus G.
- Journal Title
  
  Blood Advances
  
  Volume: 4 Issue: 19 Pages: 4912-4917
- DOI
  10.1182/bloodadvances.2020001926
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21547
[Journal Article] Blockade of CD47 or SIRPα: a new cancer immunotherapy2020
- Author(s)
  Murata Yoji、Saito Yasuyuki、Kotani Takenori、Matozaki Takashi
- Journal Title
  
  Expert Opinion on Therapeutic Targets
  
  Volume: 24 Issue: 10 Pages: 945-951
- DOI
  10.1080/14728222.2020.1811855
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07385, KAKENHI-PROJECT-20K21547, KAKENHI-PROJECT-18H04032
[Journal Article] Importance of methodology in the evaluation of renal mononuclear phagocytes and analysis of a model of experimental nephritis with Shp1 conditional knockout mice2020
- Author(s)
  Watanabe Mitsuharu、Kaneko Yoriaki、Ohishi Yuko、Kinoshita Masato、Sakairi Toru、Ikeuchi Hidekazu、Maeshima Akito、Saito Yasuyuki、Ohnishi Hiroshi、Nojima Yoshihisa、Matozaki Takashi、Hiromura Keiju
- Journal Title
  
  Biochemistry and Biophysics Reports
  
  Volume: 22 Pages: 100741-100741
- DOI
  10.1016/j.bbrep.2020.100741
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08231, KAKENHI-PROJECT-19K08902, KAKENHI-PUBLICLY-18H04685, KAKENHI-PROJECT-18H04032, KAKENHI-PROJECT-18K15190, KAKENHI-PROJECT-19H04027
[Journal Article] SIRPα on CD11c+ cells induces Th17 cell differentiation and subsequent inflammation in the CNS in experimental autoimmune encephalomyelitis2020
- Author(s)
  Nishimura Taichi、Saito Yasuyuki、Washio Ken、Komori Satomi、Respatika Datu、Kotani Takenori、Murata Yoji、Ohnishi Hiroshi、Mizobuchi Satoshi、Matozaki Takashi
- Journal Title
  
  European Journal of Immunology
  
  Volume: 50 Issue: 10 Pages: 1560-1570
- DOI
  10.1002/eji.201948410
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21547, KAKENHI-PROJECT-18H04032, KAKENHI-PROJECT-20J12857
[Journal Article] An animal model that mimics human herpesvirus 6B pathogenesis2019
- Author(s)
  Wang B, Saito Y, Nishimura M, Ren Z, Tjan LH, Refaat A, Iida-Norita R, Tsukamoto R, Komatsu M, Itoh T, Matozaki T, Mori Y
- Journal Title
  
  Journal of Virology
  
  Volume: 94 Issue: 6
- DOI
  10.1128/jvi.01851-19
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H04032, KAKENHI-PROJECT-18K15190
[Journal Article] Microglial SIRPα regulates the emergence of CD11c+ microglia and demyelination damage in white matter.2019
- Author(s)
  Sato-Hashimoto M, Nozu T, Toriba R, Horikoshi A, Akaike M, Kawamoto K, Hirose A, Hayashi H, Nagai H, Shimizu W, Saiki A., Ishikawa T, Elhanbaly R, Kotani T, Murata Y, Saito Y, Naruse M, Shibasaki K, Oldenborg P.-A, Jung S, Matozaki T, Fukazawa Y, Ohnishi H.
- Journal Title
  
  eLife
  
  Volume: - Pages: 1-29
- DOI
  10.7554/elife.42025
- NAID
  120006604638
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07363, KAKENHI-PROJECT-18K15190, KAKENHI-PUBLICLY-18H04685, KAKENHI-PUBLICLY-18H05120, KAKENHI-PROJECT-18H04032, KAKENHI-PROJECT-16H04662, KAKENHI-PROJECT-16K15189, KAKENHI-PROJECT-17K19446, KAKENHI-PROJECT-19K16909
[Journal Article] Role of lysophosphatidic acid in proliferation and differentiation of intestinal epithelial cells2019
- Author(s)
  Konno T, Kotani T, Setiawan J, Nishigaito Y, Sawada N, Imada S, Saito Y, Murata Y, Matozaki T
- Journal Title
  
  PLOS ONE
  
  Volume: 14 Issue: 4 Pages: e0215255-e0215255
- DOI
  10.1371/journal.pone.0215255
- NAID
  120006634675
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08586, KAKENHI-PROJECT-18H04032, KAKENHI-PROJECT-18K15190
[Journal Article] SIRPα+ dendritic cells promote the development of fibroblastic reticular cells in murine peripheral lymph nodes2019
- Author(s)
  Komori S, Saito Y, Respatika D, Nishimura T, Kotani T, Murata Y, Matozaki T
- Journal Title
  
  European Journal of Immunology
  
  Volume: 49 Issue: 9 Pages: 1364-1371
- DOI
  10.1002/eji.201948103
- NAID
  120006778280
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H04032, KAKENHI-PROJECT-18K15190
[Journal Article] Anti-human SIRPα antibody is a new tool for cancer immunotherapy2018
- Author(s)
  Murata Yoji、Tanaka Daisuke、Hazama Daisuke、Yanagita Tadahiko、Saito Yasuyuki、Kotani Takenori、Oldenborg Per-Arne、Matozaki Takashi
- Journal Title
  
  Cancer Science
  
  Volume: 印刷中 Issue: 5 Pages: 1300-1308
- DOI
  10.1111/cas.13548
- NAID
  120006482611
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08586, KAKENHI-PROJECT-15K08532, KAKENHI-PROJECT-16K15219
[Journal Article] Role of Csk in intestinal epithelial barrier function and protection against colitis2018
- Author(s)
  Sun Chunxiao、Murata Yoji、Imada Shinya、Konno Tasuku、Kotani Takenori、Saito Yasuyuki、Yamada Hideto、Matozaki Takashi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 504 Issue: 1 Pages: 109-114
- DOI
  10.1016/j.bbrc.2018.08.140
- NAID
  120006775950
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K15190, KAKENHI-PROJECT-18H04032, KAKENHI-PROJECT-16K08586, KAKENHI-PROJECT-16K08624
[Journal Article] Regulation by commensal bacteria of neurogenesis in the subventricular zone of adult mouse brain2018
- Author(s)
  Sawada Naoki、Kotani Takenori、Konno Tasuku、Setiawan Jajar、Nishigaito Yuka、Saito Yasuyuki、Murata Yoji、Nibu Ken-ichi、Matozaki Takashi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 498 Issue: 4 Pages: 824-829
- DOI
  10.1016/j.bbrc.2018.03.064
- NAID
  120006733123
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08586, KAKENHI-PROJECT-15K08532, KAKENHI-PROJECT-16K15219, KAKENHI-PROJECT-18K15190
[Journal Article] CD47-signal regulatory protein α signaling system and its application to cancer immunotherapy2018
- Author(s)
  Murata Yoji、Saito Yasuyuki、Kotani Takenori、Matozaki Takashi
- Journal Title
  
  Cancer Science
  
  Volume: 109 Issue: 8 Pages: 2349-2357
- DOI
  10.1111/cas.13663
- NAID
  120006517719
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K15190, KAKENHI-PROJECT-18H04032
[Journal Article] An mTORC1/2 kinase inhibitor enhances the cytotoxicity of gemtuzumab ozogamicin by activation of lysosomal function2018
- Author(s)
  Maimaitili Yimamu、Inase Aki、Miyata Yoshiharu、Kitao Akihito、Mizutani Yu、Kakiuchi Seiji、Shimono Yohei、Saito Yasuyuki、Sonoki Takashi、Minami Hironobu、Matsuoka Hiroshi
- Journal Title
  
  Leukemia Research
  
  Volume: 74 Pages: 68-74
- DOI
  10.1016/j.leukres.2018.09.017
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K15190
[Journal Article] Role of SIRPα in homeostatic regulation of T cells and fibroblastic reticular cells in the spleen.2017
- Author(s)
  Respatika Datu, Saito Yasuyuki, Washio Ken, Komori Satomi, Kotani Takenori, Okazawa Hideki, Murata Yoji, Matozaki Takashi
- Journal Title
  
  Kobe Journal of Medical Sciences
  
  Volume: 63
- NAID
  120006335579
- Data Source
  KAKENHI-PROJECT-15K08532
[Journal Article] Pathogen-Induced TLR4-TRIF Innate Immune Signaling in Hematopoietic Stem Cells Promotes Proliferation but Reduces Competitive Fitness.2017
- Author(s)
  Takizawa H, Fritsch K, Kovtonyuk LV, Saito Y, Yakkala C, Jacobs K, Ahuja AK, Lopes M, Hausmann A, Hardt WD, Gomariz A, Nombela-Arrieta C, Manz MG.
- Journal Title
  
  Cell Stem Cell
  
  Volume: 21 Issue: 2 Pages: 225-240
- DOI
  10.1016/j.stem.2017.06.013
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-INTERNATIONAL-15K21751, KAKENHI-ORGANIZER-26115001, KAKENHI-PROJECT-15K08532
[Journal Article] SIRPα+dendritic cells regulate homeostasis of fibroblastic reticular cells via TNF receptor ligands in the adult spleen2017
- Author(s)
  Saito Yasuyuki、Respatika Datu、Komori Satomi、Washio Ken、Nishimura Taichi、Kotani Takenori、Murata Yoji、Okazawa Hideki、Ohnishi Hiroshi、Kaneko Yoriaki、Yui Katsuyuki、Yasutomo Koji、Nishigori Chikako、Nojima Yoshihisa、Matozaki Takashi
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 114 Issue: 47
- DOI
  10.1073/pnas.1711345114
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08586, KAKENHI-PROJECT-16K09887, KAKENHI-PROJECT-15H05277, KAKENHI-PROJECT-16H05183, KAKENHI-PROJECT-15K08532, KAKENHI-PROJECT-16K15219
[Journal Article] Anti-SIRPα antibodies as a potential new tool for cancer immunotherapy.2017
- Author(s)
  Yanagita T, Murata Y, Tanaka D, Motegi S, Arai E, Daniwijaya EW, Hazama D, Washio K, Saito Y, Kotani T, Ohnishi H, Oldenborg PA, Verjan Garcia N, Miyasaka M, Ishikawa O, Kanai Y, Komori T, Matozaki T.
- Journal Title
  
  JCI Insight
  
  Volume: 2 Issue: 1
- DOI
  10.1172/jci.insight.89140
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-24111001, KAKENHI-PLANNED-24111005, KAKENHI-PROJECT-26291022, KAKENHI-PROJECT-26670110, KAKENHI-PROJECT-15K08532, KAKENHI-PROJECT-16K08720
[Journal Article] Peripheral blood CD34+ cells efficiently engraft human cytokine knock-in mice.2016
- Author(s)
  Saito Y, Ellegast JM, Rafiei A, Song Y, Kull D, Heikenwalder M, Rongvaux A, Halene S, Flavell RA, Manz MG.
- Journal Title
  
  Blood
  
  Volume: 128 Issue: 14 Pages: 1829-1833
- DOI
  10.1182/blood-2015-10-676452
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08532
[Journal Article] Generation of Humanized Mice for Analysis of Human Dendritic Cells.2016
- Author(s)
  Saito Y, Ellegast JM, Manz MG.
- Journal Title
  
  Methods Mol Biol
  
  Volume: 1423 Pages: 309-320
- DOI
  10.1007/978-1-4939-3606-9_22
- ISBN
  9781493936045, 9781493936069
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08532
[Journal Article] Role of Src family kinases in regulation of intestinal epithelial homeostasis.2016
- Author(s)
  Imada S, Murata Y, Kotani T, Hatano M, Sun C, Konno T, Park JH, Kitamura Y, Saito Y, Ohdan H, Matozaki T.
- Journal Title
  
  Mol Cell Biol
  
  Volume: 36 Issue: 22 Pages: 2811-2823
- DOI
  10.1128/mcb.00311-16
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26291022, KAKENHI-PROJECT-16K08624, KAKENHI-PROJECT-16K15219
[Journal Article] Dendritic cell SIRPα regulates homeostasis of dendritic cells in lymphoid organs2015
- Author(s)
  Washio K, Kotani T, Saito Y, Respatika D, Murata Y, Kaneko Y, Okazawa H, Ohnishi H, Fukunaga A, Nishigori C, Matozaki T.
- Journal Title
  
  Genes Cells
  
  Volume: - Issue: 6 Pages: 00-00
- DOI
  10.1111/gtc.12238
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24590380, KAKENHI-PUBLICLY-25112709, KAKENHI-PROJECT-25461468, KAKENHI-PROJECT-26291022, KAKENHI-PROJECT-26670142, KAKENHI-PROJECT-15K08532, KAKENHI-PROJECT-26860210
[Journal Article] Shp2 in forebrain neurons regulates synaptic plasticity, locomotion, and memory formation in mice2015
- Author(s)
  Kusakari S, Saitow F, Ago Y, Shibasaki K, Sato-Hashimoto, M., Matsuzaki, Y., Kotani T, Murata Y, Hirai H, Matsuda T, Suzuki H, Matozaki T, Ohnishi H
- Journal Title
  
  Mol. Cell. Biol.
  
  Volume: 35 Issue: 9 Pages: 1557-1572
- DOI
  10.1128/mcb.01339-14
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-23500437, KAKENHI-PUBLICLY-25112709, KAKENHI-PROJECT-25430062, KAKENHI-PROJECT-25870110, KAKENHI-PROJECT-26291022, KAKENHI-PROJECT-26670142, KAKENHI-PROJECT-26670110, KAKENHI-PUBLICLY-26111703, KAKENHI-PROJECT-15H03000, KAKENHI-PUBLICLY-26111702, KAKENHI-PUBLICLY-26117502
[Journal Article] Regulation by gut commensal bacteria of carcinoembryonic antigen-related cell adhesion molecule expression in the intestinal epithelium2015
- Author(s)
  Kitamura Y, Murata Y, Park JH, Kotani T, Imada S, Saito Y, Okazawa H, Azuma T, Matozaki T.
- Journal Title
  
  Genes Cells.
  
  Volume: - Issue: 7 Pages: 578-589
- DOI
  10.1111/gtc.12247
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-25112709, KAKENHI-PROJECT-26670142, KAKENHI-PROJECT-25460366, KAKENHI-PROJECT-26291022
[Journal Article] Protein tyrosine phosphatase SAP-1 protects against colitis through regulation of CEACAM20 in the intestinal epithelium2015
- Author(s)
  Y Murata, T Kotani, Y Supriatna, Y Kitamura, S Imada, K Kawahara, M Nishio, EW Daniwijaya, H Sadakata, S Kusakari, M Mori, Y Kanazawa, Y Saito, K Okawa, M Takeda-Morishita, H Okazawa, H Ohnishi, T Azuma, A Suzuki, T Matozaki
- Journal Title
  
  Proc Natl Acad Sci U S A
  
  Volume: 112 Issue: 31
- DOI
  10.1073/pnas.1510167112
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08532, KAKENHI-PROJECT-26670160, KAKENHI-PROJECT-25460366, KAKENHI-PROJECT-26670142, KAKENHI-PROJECT-26291022
[Journal Article] Essential roles of SIRPα in homeostatic regulation of skin dendritic cells.2011
- Author(s)
  Iwamura, H.、Saito, Y.、Sato-Hashimoto, M, 他9名
- Journal Title
  
  Immunol. Lett. Vol.135
  
  Pages: 100-107
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790936
[Journal Article] Requirement of SIRPα for protective immunity against Leishmania Major.2010
- Author(s)
  Morimoto, N.、Murata, Y.、Saito, Y., 他8名
- Journal Title
  
  Biochem.Biophys.Res.Commun. Vol.401
  
  Pages: 385-389
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790936
[Journal Article] Promotion of cell spreading and migration by vascular endothelial-protein tyrosine phosphatase (VE-PTP) in cooperation with integrins.2010
- Author(s)
  Mori, M.、Murata, Y.、Saito, Y., 他7名
- Journal Title
  
  J.Cell.Physiol. Vol.224
  
  Pages: 195-204
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790936
[Journal Article] Expression of PTPRO in the interneurons of adult mouse olfactory bulb.2010
- Author(s)
  Kotani, T.、Murata, Y.、Saito, Y., 他5名
- Journal Title
  
  J.Comp.Neurol. Vol.518
  
  Pages: 119-136
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790936
[Journal Article] Role of SIRPα in regulation of mucosal immunity in the intestine.2010
- Author(s)
  Kanazawa, Y.、Saito, Y.、Suriatna, Y., 他10名
- Journal Title
  
  Genes Cells Vol.15
  
  Pages: 1189-1200
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790936
[Journal Article] Regulation by SIRPα of dendritic cell homeostasis in lymphoid tissues.2010
- Author(s)
  Saito, Y.、Iwamura, H.、Kaneko, T., 他11名
- Journal Title
  
  Blood Vol.116
  
  Pages: 3517-3525
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790936
[Journal Article] Regulation by SIRPα of dendritic cell homeostasis in lymphoid tissues2010
- Author(s)
  Saito, Y., 他
- Journal Title
  
  Blood
  
  Volume: 116 Pages: 3517-3525
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790936
[Journal Article] Tyrosine phosphorylation of R3 subtype receptor-type protein tyrosine phosphatases and their complex formations with Grb2 or Fyn.2010
- Author(s)
  Murata, Y.、Mori, M.、Saito, Y., 他6名
- Journal Title
  
  Genes Cells Vol.15
  
  Pages: 513-524
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790936
[Journal Article] SIRPαによる樹状細胞の機能制御2009
- Author(s)
  齊藤泰之、村田陽二、大西浩史、的崎尚
- Journal Title
  
  臨床免疫・アレルギー科 Vol.52
  
  Pages: 494-498
- Data Source
  KAKENHI-PROJECT-21790936
[Journal Article] Protein tyrosine phosphatase SHP-2 : a proto-oncogene product that promotes Ras activation.2009
- Author(s)
  Matozaki, T.、Murata, Y.、Saito, Y., 他6名
- Journal Title
  
  Cancer Sci. Vol.100
  
  Pages: 1786-1793
- NAID
  10027195202
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790936
[Journal Article] SIRPαによる樹状細胞の制御機構2009
- Author(s)
  齊藤泰之, 他
- Journal Title
  
  臨床免疫・アレルギー科 52
  
  Pages: 494-498
- Data Source
  KAKENHI-PROJECT-21790936
[Presentation] CD47 promotes peripheral T cell survival by preventing dendritic cell-mediated T cell necroptosis2024
- Author(s)
  Saito Y, Komori S, Afroj T, Takai T, Oduori OS, Kotani T, Murata Y, Matozaki T
- Organizer
  Keystone symposia
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08504
[Presentation] SIRPα is a key regulator of cDC2A homeostasis and peripheral T cell surveillance2024
- Author(s)
  Satomi Komori, Tomoko Takai, Afroj Tania, Takenori Kotani, Yoji Murata, Takashi Matozaki, Yasuyuki Saito
- Organizer
  17th International Symposium on Dendritic Cells
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08504
[Presentation] CD47 PROMOTES PERIPHERAL T CELL SURVIVAL BY PREVENTING DENDRITIC CELL-MEDIATED T CELL NECROPTOSIS2024
- Author(s)
  Satomi Komori, Yasuyuki Saito, Tania Afroj, Tomoko Takai, Takenori Kotani, Yoji Murata, Takashi Matozaki
- Organizer
  FASEB Science Research Conferences
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08504
[Presentation] Anti-tumor effect of a human SIRPα antibody targeting human macrophages in a humanized mouse model2024
- Author(s)
  Tania Afroj, Satomi Komori, Ikumi Katano, Takeshi Takahashi, Takenori Kotani, Yoji Murata, Takashi Matozaki, and Yasuyuki Saito
- Organizer
  53rd Annual Meeting of Japanese Society for immunology
- Data Source
  KAKENHI-PROJECT-22K08504
[Presentation] Preclinical evaluation of the efficacy of an antibody to human SIRPα for cancer immunotherapy in humanized mouse models.2024
- Author(s)
  Saito Y, Tania A, Komori S, Takai T, Kotani T, Murata Y, Matozaki T
- Organizer
  The 5th Japan-Taiwan Bilateral Conference on Protein Phosphatase
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08504
[Presentation] Development of an anti-SIRPα antibody cancer immunotherapy model targeting human macrophages2024
- Author(s)
  Tania Afroj, Yasuyuki Saito, Satomi Komori, Tomoko Takai, Okechi S. Oduori, Takenori Kotani, Yoji Murata, and Takashi Matozaki
- Organizer
  83rd Annual Meeting of Japanese Cancer Society
- Data Source
  KAKENHI-PROJECT-22K08504
[Presentation] 細胞リンパ腫に対するマクロファージ標的療法のヒト化マウスモデルを用いた前臨床評価2024
- Author(s)
  齊藤泰之, Tania Afroj, 小森里美, 高井智子, 小谷武徳, 船越洋平, 村田陽二, 薬師神公和, 松岡広, 南博信, Markus G. Manz, 的崎尚
- Organizer
  第86回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-22K08504
[Presentation] CD47 promotes peripheral T cell survival by preventing dendritic cell-mediated T cell necroptosis2023
- Author(s)
  Saito Y, Komori S, Afroj T, Takai T, Oduori OS, Nitta E, Kotani T, Murata Y, Nitta R, Matozaki T
- Organizer
  The 85th Annual Meeting of the Japanese Society of Hematology
- Data Source
  KAKENHI-PROJECT-22K08504
[Presentation] Preclinical evaluation of macrophage-targeted immunotherapy in vivo using a humanized mouse model2023
- Author(s)
  Saito Y, Tania A, Iida-Norita R, Komori S, Takai T, Oduori OS, Kotani T, Koma Y, Murata Y, Yokozaki H, Matozaki T
- Organizer
  The 82nd Annual Meeting of the Japan Cancer Association
- Data Source
  KAKENHI-PROJECT-22K08504
[Presentation] Preclinical evaluation of the efficacy of an antibody to human SIRPα for cancer immunotherapy in humanized mouse models2023
- Author(s)
  Saito Y, Tania A, Komori S, Takai T, Oduori OS, Kotani T, Funakoshi Y, Murata Y, Yakushijin K, Matsuoka H, Minami H, Manz MG, Matozaki T
- Organizer
  65th American society of hematology annual meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08504
[Presentation] Preclinical evaluation of macrophage-targeted immunotherapy in vivo using a humanized mouse model2023
- Author(s)
  Saito Y, Tania A, Iida-Norita R, Komori S, Takai T, Oduori OS, Kotani T, Koma Y, Murata Y, Yokozaki H, Matozaki T
- Organizer
  The 2nd JCA-AACR Precision Cancer Medicine International Conference
- Data Source
  KAKENHI-PROJECT-22K08504
[Presentation] SIRPα maintains cDC2 survival by regulating the Nr4a3 expression2022
- Author(s)
  Satomi Komori, Yasuyuki Saito, Taichi Nishimura, Takenori Kotani, Yoji Murata, Takashi Matozaki
- Organizer
  DC2022 国際樹状細胞学会
- Data Source
  KAKENHI-PROJECT-22K08504
[Presentation] Dendritic cells regulate peripheral T cell survival through the CD47-SIRPαsignaling2022
- Author(s)
  Yasuyuki Saito, Satomi Komori, Hiroki Yoshida, Risa Sugihara, Takenori Kotani, Yoji Murata, Takashi Matozaki
- Organizer
  DC2022 国際樹状細胞学会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08504
[Presentation] Preclinical evaluation of macrophage-mediated anti-tumor effects by using a humanized MITRG mouse model2022
- Author(s)
  Yasuyuki Saito, Rie Iida-Norita, Afroj Tania, Satomi Komori, Takenori Kotani, Yoji Murata, Markus G Manz, Takashi Matozaki
- Organizer
  6TH INTERNATIONAL WORKSHOP ON HUMANIZED MICE (IWHM6)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08504
[Presentation] Dendritic cells regulate peripheral T cell survival through the CD47-SIRPαsignaling2022
- Author(s)
  Yasuyuki Saito, Satomi Komori, Hiroki Yoshida, risa Sugihara, Tomoko Takai, Takenori Kotani, Yoji Murata, Takashi Matozaki
- Organizer
  第51回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-22K08504
[Presentation] 新規ヒト化マウスを用いたマクロファージを介した抗腫瘍効果の前臨床評価モデル Preclinical evaluation of macrophage-mediated anti-tumor effct by using a novel humanized mouse model2022
- Author(s)
  齊藤泰之、飯田理恵、小森里美、小谷武徳、村田陽二、横崎宏、的崎尚
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-22K08504
[Presentation] A novel humanized mouse model in vivo evaluation of cancer immunotherapy targeting human macrophages2021
- Author(s)
  Yasuyuki Saito, Rie Iida, Daisuke Hazama, Takenori Kotani, Yoji Murata, Hiroshi Yokozaki, Takashi Matozaki
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K21547
[Presentation] A novel humanized mouse model for assessing human macrophage-targeted cancer immunotherapy in vivo2021
- Author(s)
  Rie Iida-Norita, Yasuyuki Saito, Daisuke Hazama, Satomi Komori, Hiroki Yoshida, Risa Sugihara, Yoji Murata, and Takashi Matozaki
- Organizer
  神戸大学・理研BDR合同シンポジウム
- Data Source
  KAKENHI-PROJECT-20K21547
[Presentation] Preclinical Evaluation of the efficacy of anti-human SIRPα antibody for cancer immunotherapy by the use of humanized mice2021
- Author(s)
  Yasuyuki Saito, Rie Iida-Norita, Daisuke Hazama, Refaat Alaa, Satomi Komori, Takenori Kotani, Yoji Murata, Takashi Matozaki
- Organizer
  第50回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-20K21547
[Presentation] A novel humanized mouse model for assessing human macrophage-targeted cancer immunotherapy in vivo2020
- Author(s)
  Rie Iida-Norita, Yasuyuki Saito, Daisuke Hazama, Satomi Komori, Hiroki Yoshida, Risa Sugihara, Yoji Murata, and Takashi Matozaki
- Organizer
  14th International Conference on Protein Phosphatase
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21547
[Presentation] Humanized mouse models for in vivo evaluation of cancer immunotherapy targeting human macrophages2020
- Author(s)
  Yasuyuki Saito, Rie Iida, Daisuke Hazama, Takenori Kotani, Yoji Murata, Takashi Matozaki
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K21547
[Presentation] SIRPα抗体を用いた新規のがん免疫療法:CD20及びPD-1抗体との併用による有効性2019
- Author(s)
  的崎　尚、村田　陽二、齊藤　泰之、小谷　武徳
- Organizer
  第78回日本癌学会総会
- Data Source
  KAKENHI-PROJECT-18K15190
[Presentation] 細胞間シグナルCD47-SIRPα系による血球寿命制御とその臨床応用2019
- Author(s)
  的崎　尚、齊藤　泰之、小谷　武徳、村田　陽二
- Organizer
  第92回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-18K15190
[Presentation] 膜型分子SIRPαを標的とする新たな免疫チェックポイント阻害剤の開発2019
- Author(s)
  羽間　大祐、村田　陽二、田中　大介、岡本　武士、齊藤　泰之、小谷　武徳、西村　善博、的崎　尚
- Organizer
  第9回ホスファターゼ研究会学術集会
- Data Source
  KAKENHI-PROJECT-18K15190
[Presentation] SIRPα陽性樹状細胞による末梢リンパ節ストローマ細胞の発達制御2019
- Author(s)
  小森　里美、齊藤　泰之、ダトゥレスパティカ、西村　太一、小谷　武徳、村田　陽二、的崎　尚
- Organizer
  第9回ホスファターゼ研究会学術集会
- Data Source
  KAKENHI-PROJECT-18K15190
[Presentation] A nobel macrocycle peptide targets CD47-SIRPalpha axis and enhances the macrophage-mediated tumor killing2019
- Author(s)
  Hazama D, Murata Y, Tanaka D, Okamoto T, Saito Y, Kotani T, Nishimura Y, Matozaki T
- Organizer
  78回日本癌学会総会
- Data Source
  KAKENHI-PROJECT-18K15190
[Presentation] 大腸上皮の恒常性制御におけるTsc2-mTORC1シグナルの役割2019
- Author(s)
  小谷　武徳、ジャジャルセティアワン、井原　紀子、岡本　沙樹、村田　陽二、齊藤　泰之、的崎　尚
- Organizer
  第9回ホスファターゼ研究会学術集会
- Data Source
  KAKENHI-PROJECT-18K15190
[Presentation] Role of Tsc2-mTORC1 signaling in regulation of colonic epithelial homeostasis2019
- Author(s)
  Kotani T, Setiawan J, Ihara N, Okamoto S, Murata Y, Saito Y, Matozaki T
- Organizer
  第78回日本癌学会総会
- Data Source
  KAKENHI-PROJECT-18K15190
[Presentation] Importance of SIRPα+ dendric cells for the development of fibroblastic reticular cells of peripheral lymph nodes2019
- Author(s)
  Komori S, Saito Y, Respatika D, Nishimura T, Kotani T, Murata Y, Matozaki T
- Organizer
  第92回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-18K15190
[Presentation] チロシンホスファターゼ SHP-1/2 結合タンパク質 SIRPαによる自然免疫細胞の機能制御2019
- Author(s)
  村田　陽二、齊藤　泰之、小谷　武徳、的崎　尚
- Organizer
  第92回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-18K15190
[Presentation] 新規SIRPα阻害剤の開発とその抗腫瘍効果2019
- Author(s)
  村田　陽二、羽間　大祐、田中　大介、岡本　武士、齊藤　泰之、小谷　武徳、的崎　尚
- Organizer
  第18回生体機能研究会
- Data Source
  KAKENHI-PROJECT-18K15190
[Presentation] Xenograft mouse models for in vivo evaluation of cancer immunotherapy targeting human macrophages2018
- Author(s)
  Saito Y, Hazama D, Murata Y, Manz MG, Matozaki
- Organizer
  Regeneron HIS Mice Workshop
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15190
[Presentation] SIRPα+ dendritic cells regulate homeostasis of fibroblastic reticular cells via TNF receptor ligands in the adult spleen2018
- Author(s)
  Saito Y
- Organizer
  Workshop on Frontiers in Phosphatase Research and Drug Discovery
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15190
[Presentation] Critical role of SIRPαon dendritic cells for the development of experimental autoimmune encephalomyelitis2018
- Author(s)
  Nishimura T, Saito Y, Washio K, Komori S, Respatika D, Kotani T, Murata Y, Mizobuchi S, Matozaki T
- Organizer
  Workshop on Frontiers in Phosphatase Research and Drug Discovery
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15190
[Presentation] SIRPα陽性樹状細胞による脾臓細網線維芽細胞の恒常性の制御2018
- Author(s)
  齊藤　泰之、小森　里美、Datu　Respatika、鷲尾　健、西村　太一、小谷　武徳、村田　陽二、的崎　尚
- Organizer
  第80回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-18K15190
[Presentation] 実験的自己免疫性脳脊髄炎の発症制御におけるCD47-SIRPα系の役割について2018
- Author(s)
  西村　太一、齊藤　泰之、鷲尾　健、小森　里美、小谷　武徳、村田　陽二、溝渕　知司、的崎　尚
- Organizer
  第17回生体機能研究会
- Data Source
  KAKENHI-PROJECT-18K15190
[Presentation] SIRPα+ dendritic cells regulate homeostasis of fibroblastic reticular cells via TNF receptor ligands in the adult spleen2018
- Author(s)
  Satomi Komori, Yasuyuki Saito, Datu Respatika, Takenori Kotani, Yoji Murata, Takashi Matozaki
- Organizer
  第２回UW・UO・KUシンポジウム
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08532
[Presentation] Importance of SIRPα on dendritic cells for the development of exprerimental autoimmune encephalomyelitis2018
- Author(s)
  Nishimura T, Saito Y, Komori S, Respatika D, Washio K, Kotani T, Murata Y, Mizobushi S, Matozaki T
- Organizer
  第47回日本免疫学学術集会
- Data Source
  KAKENHI-PROJECT-18K15190
[Presentation] SIRPα＋Dendritic Cells regulate　organization of lymph node stromal sells in vivo2018
- Author(s)
  Komori S, Saito Y, Respatika D, Kotani T, Murata Y, Matozaki T
- Organizer
  第47回日本免疫学学術集会
- Data Source
  KAKENHI-PROJECT-18K15190
[Presentation] SIRPα+ Dendritic Cells regulate homeostasis of fibroblastic reticular cells via TNF receptor ligands in the adult spleen2018
- Author(s)
  Saito Y, Komori S, Respatika D, Washio K, Kotani T, Murata Y, Matozaki T
- Organizer
  15th International Symposium on Dendritic Cells
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15190
[Presentation] SIRPα+ dendritic cells regulate homeostasis of fibroblastic reticular cells via TNF receptor ligands in the adult spleen2017
- Author(s)
  Yasuyuki Saito, Satomi Komori, Datu Respatika, Ken Washio, Takenori Kotani, Yoji Murata, Hiroshi Ohnishi, Katsuyuki Yui, Koji Yasutomo, Takashi Matozaki
- Organizer
  The 46th annual meeting of the japanese society for immunology
- Data Source
  KAKENHI-PROJECT-15K08532
[Presentation] Anti-SIRPalpha antibodies provide a basis for new approaches to canser immunotherapy2017
- Author(s)
  Takashi Matozaki,Yoji Murata, Tadahiro Yanagita, Yasuyuki Saito, Takenori Kotani
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-15K08532
[Presentation] 免疫系ヒト化マウスを用いた新規がん異種移植マウスモデルの作成2017
- Author(s)
  齊藤　泰之、羽間　大祐、小谷　武徳、村田　陽二、的崎　尚
- Organizer
  第16回生体機能研究会
- Data Source
  KAKENHI-PROJECT-15K08532
[Presentation] Development of a novel primary culture system for lymphoid organ fibroblastic reticular cells2017
- Author(s)
  Komori Satomi, Yasuyuki Saito, Datu Respatika, Takenori Kotani, Yoji Murata, Takashi Matozaki
- Organizer
  The 46th annual meeting of the japanese society for immunology
- Data Source
  KAKENHI-PROJECT-15K08532
[Presentation] 二次リンパ組織ストローマ細胞の新規初代培養系の樹立と増殖・制御機構の解明2017
- Author(s)
  小森　里美、齊藤　泰之、Datu Respatika、小谷　武徳、村田　陽二、的崎　尚
- Organizer
  第16回生体機能研究会
- Data Source
  KAKENHI-PROJECT-15K08532
[Presentation] Blockage of CD47-SIRPαsignaling provide a novel cancer immunotherapy2017
- Author(s)
  Takashi Matozaki, Yoji Murata, Tadahiko Yanagita, Yasuyuki Saito, Takenori Kotani,
- Organizer
  Europhosphatase 2017:Phosphatases in cell fates and decisions
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08532
[Presentation] Establishment of a potential new PDX mouse model for personalized cancer immunotherapy2017
- Author(s)
  Yasuyuki Saito, Yoji Murata, Takenori Kotani, Richard A. Flavell, Markus G. Manz, Takashi Matozaki
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-15K08532
[Presentation] SIRPα+ dendritic cells regulate homeostasis of fibroblastic reticular cells via TNF receptor ligands in the adult spleen2017
- Author(s)
  Yasuyuki Saito, Satomi Komori, Datu Respatika, Ken Washio, Takenori Kotani, Yoji Murata, Hiroshi Ohnishi, Katsuyuki Yui, Koji Yasutomo, Takashi Matozaki
- Organizer
  The 5th annual meeting of the international cytokine and interferon society, ICIS 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08532
[Presentation] Role of SIRPαin the homeostasis of fibroblastic reticular cells by dendritic cells in the spleen2016
- Author(s)
  Datu Respatika, Yasuyuki Saito, Ken Washio, Satomi Komori, Takenori Kotani, Yoji Murata, Takashi Matozaki
- Organizer
  第12回プロテインホスファターゼ国際カンファレンス＆革新がんゲノム国際シンポジウム
- Place of Presentation
  近畿大学東大阪キャンパス
- Year and Date
  2016-10-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26291022
[Presentation] Role of SIRPαin the homeostasis of fibroblastic reticular cells by dendritic cells in the spleen2016
- Author(s)
  Datu Respatika, Yasuyuki Saito, Ken Washio, Satomi Komori, Takenori Kotani, Yoji Murata, Takashi Matozaki
- Organizer
  第12回プロテインホスファターゼ国際カンファレンス＆革新がんゲノム国際シンポジウム
- Place of Presentation
  近畿大学東大阪キャンパス
- Year and Date
  2016-10-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08532
[Presentation] The anti-SIRPα antibody prevents tumor formation: a novel strategy for cancer therapy /抗SIRPα抗体を用いた新たながん治療法2016
- Author(s)
  栁田　匡彦、村田　陽二、田中　大介、齊藤　泰之、小谷　武徳、古森　孝英、的崎　尚
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-26291022
[Presentation] Peripheral blood CD34+ cells efficiently engraft human cytokine knock-in immunodeficient mice2016
- Author(s)
  Yasuyuki Saito, Jana M. Ellegast, Yuanbin Song, Daniel Kull, Mathias Heikenwalder, Anthony Rongvaux, Stephanie Helene, Richard A. Flavell, Markus G. Manz
- Organizer
  第78回日本血液学会学術集会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-15K08532
[Presentation] Role of SIRPα on dendritic cells in homeostatic regulation of fibroblastic reticular cells in the spleen2016
- Author(s)
  Datu Respatika, Yasuyuki Saito, Ken Washio, Satomi Komori, Takenori Kotani, Yoji Murata, Takashi Matozaki
- Organizer
  第45回日本免疫学会学術集会
- Place of Presentation
  沖縄コンベンションセンター
- Year and Date
  2016-12-05
- Data Source
  KAKENHI-PROJECT-15K08532
[Presentation] Human cytokine knock-in hSIRPα-Tg Rag2-/-Il2rg-/- mice efficiently support engraftment of peripheral blood human CD34+ cells in vivo2016
- Author(s)
  Yasuyuki Saito, Jana Ellegast, Daniel Kull, Mathias Heikenwaelder, Richard Flavell, Markus Manz
- Organizer
  5th International Workshop on Humanized Mice (IWHM5)
- Place of Presentation
  Zurich, Switzerland (University of Zurich)
- Year and Date
  2016-01-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08532
[Presentation] 白質におけるミクログリア恒常性制御2016
- Author(s)
  野津　智美、橋本　美穂、Ruwaida Elhanbaly、石川　達也、齊藤　泰之、小谷　武徳、村田　陽二、深澤　有吾、的崎　尚、大西　浩史
- Organizer
  第38回日本生物学的精神医学会、第59回日本神経化学会大会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2016-09-08
- Data Source
  KAKENHI-PROJECT-26291022
[Presentation] Human hemato-lymphoid system development in human cytokine knock-in mice engrafted with adult donor-derived CD34+ cells2016
- Author(s)
  Yasuyuki Saito, Takashi Matozaki, Richard A. Flavell, Markus G. Manz
- Organizer
  第12回プロテインホスファターゼ国際カンファレンス＆革新がんゲノム国際シンポジウム
- Place of Presentation
  近畿大学東大阪キャンパス
- Year and Date
  2016-10-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26291022
[Presentation] Role of SIRPα on dendritic cells in homeostatic regulation of fibroblastic reticular cells in the spleen2016
- Author(s)
  Datu Respatika, Yasuyuki Saito, Ken Washio, Satomi Komori, Takenori Kotani, Yoji Murata, Takashi Matozaki
- Organizer
  第45回日本免疫学会学術集会
- Place of Presentation
  沖縄コンベンションセンター
- Year and Date
  2016-12-05
- Data Source
  KAKENHI-PROJECT-26291022
[Presentation] SIRPα欠損マウスはLPS投与によって誘導される低体温症が重症化する2016
- Author(s)
  橋本　美穂、野津　智美、浦野　江里子、齊藤　泰之、小谷　武徳、村田　陽二、的崎　尚、大西　浩史
- Organizer
  第38回日本生物学的精神医学会、第59回日本神経化学会大会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2016-09-08
- Data Source
  KAKENHI-PROJECT-26291022
[Presentation] Role of SIRPαon dendritic cells in homeostatic regulation of fibroblastic reticular cells in the spleen2016
- Author(s)
  Datu Respatika, Yasuyuki Saito, Ken Washio, Satomi Komori, Takenori Kotani, Yoji Murata, Takashi Matozaki
- Organizer
  第15回生体機能研究会
- Place of Presentation
  淡路夢舞台国際会議場
- Year and Date
  2016-07-01
- Data Source
  KAKENHI-PROJECT-26291022
[Presentation] Therapeutic application of anti-SIRPαantibody in cancer treatment2016
- Author(s)
  Tadahiko Yanagita, Yoji Murata, Daisuke Tanaka, Yasuyuki Saito, Takenori Kotani, Takahide Komori, Takashi Matozaki
- Organizer
  第12回プロテインホスファターゼ国際カンファレンス＆革新がんゲノム国際シンポジウム
- Place of Presentation
  近畿大学東大阪キャンパス
- Year and Date
  2016-10-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26291022
[Presentation] Role of SIRPαon dendritic cells in homeostatic regulation of fibroblastic reticular cells in the spleen2016
- Author(s)
  Datu Respatika, Yasuyuki Saito, Ken Washio, Satomi Komori, Takenori Kotani, Yoji Murata, Takashi Matozaki
- Organizer
  第15回生体機能研究会
- Place of Presentation
  淡路夢舞台国際会議場
- Year and Date
  2016-07-01
- Data Source
  KAKENHI-PROJECT-15K08532
[Presentation] Essential Role of SIRPA on Dendritic Cells in Homeostatic Regulation of Spleen Stromal Cells2016
- Author(s)
  Datu Respatika, Yasuyuki Saito, Ken Washio, Satomi Komori, Takenori Kotani, Yoji Murata, Takashi Matozaki
- Organizer
  第7回日本プロテインホスファターゼ研究会学術集会
- Place of Presentation
  基礎生物学研究所（愛知県・岡崎市）
- Year and Date
  2016-01-29
- Data Source
  KAKENHI-PROJECT-15K08532
[Presentation] 細胞間シグナルCD47-SIRPα系の生理機能とその臨床応用/Role of the CD47-SIRPalpha system and its therapeutic application2016
- Author(s)
  的崎　尚、村田　陽二、齊藤　泰之、小谷　武徳、栁田　匡彦、田中　大介、大西　浩史
- Organizer
  第89回日本生化学会大会
- Place of Presentation
  仙台国際センター
- Year and Date
  2016-09-26
- Data Source
  KAKENHI-PROJECT-26291022
[Presentation] Human hemato-lymphoid system development in human cytokine knock-in mice engrafted with adult donor-derived CD34+ cells2016
- Author(s)
  Yasuyuki Saito, Takashi Matozaki, Richard A. Flavell, Markus G. Manz
- Organizer
  第12回プロテインホスファターゼ国際カンファレンス＆革新がんゲノム国際シンポジウム
- Place of Presentation
  近畿大学東大阪キャンパス
- Year and Date
  2016-10-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08532
[Presentation] Essential Role of SIRPα on Dendritic Cells in Homeostatic Regulation of Spleen Stromal Cells2016
- Author(s)
  Datu Respatika, Yasuyuki Saito, Ken Washio, Satomi Komori, Takenori Kotani, Yoji Murata, Takashi Matozaki
- Organizer
  第7回日本プロテインホスファターゼ研究会学術集会
- Place of Presentation
  基礎生物学研究所（愛知県・岡崎市）
- Year and Date
  2016-01-29
- Data Source
  KAKENHI-PROJECT-26291022
[Presentation] SAP-1 and CEACAM20 protect against colitis in the intestinal epithelium2015
- Author(s)
  Yoji Murata, Takenori Kotani, Yana Supriatna, Yasuaki Kitamura, Shinya Imada, Yasuyuki Saito, Hideki Okazawa, Hiroshi Ohnishi, Takashi Matozaki
- Organizer
  FASEB
- Place of Presentation
  The Steamboat Grand, SteamboatSprings （USA）
- Year and Date
  2015-08-02
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26291022
[Presentation] Regulation of dendritic cell and stromal-cell homeostasis by dendritic cell-SIRPα in the spleen2015
- Author(s)
  Yasuyuki Saito
- Organizer
  2015University of Washington and Kobe University joint symposium 2015神戸大学・ワシントン大学国際合同シンポジウム
- Place of Presentation
  University of Washington, Seattle （USA）
- Year and Date
  2015-09-10
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26291022
[Presentation] 細胞間シグナル伝達システムCD47-SIRPα系のがん治療への応用2015
- Author(s)
  栁田　匡彦、村田　陽二、田中　大介、小谷　武徳、齊藤　泰之、古森　孝英、的崎　尚
- Organizer
  第14回生体機能研究会
- Place of Presentation
  ザ・プリンス箱根（神奈川県・箱根町）
- Year and Date
  2015-07-25
- Data Source
  KAKENHI-PROJECT-26291022
[Presentation] Development of a human hemato-lymphoid system in human cytokine knock-in Rag2-/-Il2rg-/- mice engrafted with peripheral blood mobilized CD34+ cells2015
- Author(s)
  Yasuyuki Saito, Jana Ellegast, Daniel Kull, Mathias Heikenwaelder, Richard Flavell, Markus Manz
- Organizer
  第44回日本免疫学会学術集会
- Place of Presentation
  北海道札幌市(札幌コンベンションセンター)
- Year and Date
  2015-11-18
- Data Source
  KAKENHI-PROJECT-15K08532
[Presentation] Role of C-terminal Src kinase(Csk) and Src family kinases in homeostasis of the intestinal epithelium2015
- Author(s)
  Shinya Imada, Yoji Murata, Yasuaki Kitamura, Jung-ha Park, Masaki Hatano, Takenori Kotani, Yasuyuki Saito, Hideki Ohdan, Takashi Matozaki
- Organizer
  FASEB
- Place of Presentation
  The Steamboat Grand, SteamboatSprings （USA）
- Year and Date
  2015-08-02
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26291022
[Presentation] Essential role of SIRPα on dendritic cells in Homeostatic regulation of the secondary lymphoid organ2015
- Author(s)
  Datu Respatika, Yasuyuki Saito, Ken Washio, Satomi Komori, Takenori Kotani, Yoji Murata, Yoriaki Kaneko, Hideki Okazawa, Hiroshi Ohnishi, Atsushi Fukunaga, Chikako Nishigori, and Takashi Matozaki
- Organizer
  2015University of Washington and Kobe University joint symposium 2015神戸大学・ワシントン大学国際合同シンポジウム
- Place of Presentation
  University of Washington, Seattle （USA）
- Year and Date
  2015-09-10
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26291022
[Presentation] Essential role of SIRPα on dendritic cells in Homeostatic regulation of the secondary lymphoid organ2015
- Author(s)
  Datu Respatika, Yasuyuki Saito, Ken Washio, Satomi Komori, Takenori Kotani, Yoji Murata, Yoriaki Kaneko, Hideki Okazawa, Hiroshi Ohnishi, Atsushi Fukunaga, Chikako Nishigori, Takashi Matozaki
- Organizer
  2015University of Washington and Kobe University joint symposium 2015神戸大学・ワシントン大学国際合同シンポジウム
- Place of Presentation
  Seattle, USA(University of Washington)
- Year and Date
  2015-09-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08532
[Presentation] 異種間移植におけるCD47-SIRPα系の役割とその応用2015
- Author(s)
  齊藤　泰之、的崎　尚
- Organizer
  第14回生体機能研究会
- Place of Presentation
  神奈川県足柄下郡(ザ・プリンス箱根)
- Year and Date
  2015-07-26
- Data Source
  KAKENHI-PROJECT-15K08532
[Presentation] 異種間移植におけるCD47-SIRPα系の役割とその応用2015
- Author(s)
  齊藤　泰之、的崎　尚
- Organizer
  第14回生体機能研究会
- Place of Presentation
  ザ・プリンス箱根（神奈川県・箱根町）
- Year and Date
  2015-07-25
- Data Source
  KAKENHI-PROJECT-26291022
[Presentation] Regulation of dendritic cell and stromal-cell homeostasis by dendritic cell-SIRPα in the spleen2015
- Author(s)
  Yasuyuki Saito
- Organizer
  2015University of Washington and Kobe University joint symposium 2015神戸大学・ワシントン大学国際合同シンポジウム
- Place of Presentation
  Seattle, USA(University of Washington)
- Year and Date
  2015-09-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08532
[Presentation] Essential roles of the CD47-SIRPα for dendritic cell homeostasis in lymphoid tissues2010
- Author(s)
  Saito, Y., 他
- Organizer
  JSH International Symposium 2010
- Place of Presentation
  秋田大学
- Year and Date
  2010-07-16
- Data Source
  KAKENHI-PROJECT-21790936
[Presentation] Essential role of the CD47-SIRPα signaling system for dendritic cell homeostasis in lymphoid tissues.2010
- Author(s)
  Saito, Y., 他
- Organizer
  JSH International Symposium 2010
- Place of Presentation
  秋田大学(秋田県)
- Year and Date
  2010-07-16
- Data Source
  KAKENHI-PROJECT-21790936
[Presentation] Regulation by SIRPα of dendritic cell homeostasis in lymphoid tissues.2010
- Author(s)
  Saito, Y., 他
- Organizer
  11th International Symposium on Dendritic Cells in Fundamental and Clinical Immunology
- Place of Presentation
  Lugano Convention Centre(ルガーノ、スイス)
- Year and Date
  2010-09-28
- Data Source
  KAKENHI-PROJECT-21790936
[Presentation] Regulation by SIRPα of homeostasis of lymphoid tissue dendritic cells.2010
- Author(s)
  Saito, Y., 他
- Organizer
  14th International Congress of Immunology
- Place of Presentation
  神戸国際会議場(兵庫県)
- Year and Date
  2010-08-25
- Data Source
  KAKENHI-PROJECT-21790936
[Presentation] Regulation by SIRPα of dendritic cell homeostasis in lymphoid tissues2010
- Author(s)
  Saito, Y., 他
- Organizer
  11th International Symposium on Dendritic Cells in Fundamental and Clinical Immunology
- Place of Presentation
  Lugano, Switzerland
- Data Source
  KAKENHI-PROJECT-21790936
[Presentation] Regulation by SIRPα of homeostasis of lymphoid tissue dendritic cells2010
- Author(s)
  Saito, Y., 他
- Organizer
  14th International Congress of Immunology
- Place of Presentation
  神戸国際会議場
- Year and Date
  2010-08-25
- Data Source
  KAKENHI-PROJECT-21790936
[Presentation] CD47-SIRPαシグナル系による樹状細胞の恒常性の制御2009
- Author(s)
  齊藤泰之, 他
- Organizer
  第4回日本プロテインホスファターゼ研究会
- Place of Presentation
  熊本大学
- Data Source
  KAKENHI-PROJECT-21790936
[Presentation] Essenntial roles of the CD47-SIRPα signaling for homeostasis of lymphoid tissue dendritic cells.2009
- Author(s)
  Saito, Y., 他
- Organizer
  The First International Kishimoto Fundation Symposium
- Place of Presentation
  大阪国際会議場(大阪府)
- Data Source
  KAKENHI-PROJECT-21790936
[Presentation] CD47-SIRPαシグナル系によるリンパ組織内樹状細胞の恒常性の制御2009
- Author(s)
  齊藤泰之, 他
- Organizer
  第71回日本血液学会
- Place of Presentation
  京都国際会議場(京都府)
- Year and Date
  2009-10-23
- Data Source
  KAKENHI-PROJECT-21790936
[Presentation] CD47-SIRPαシグナル系による樹状細胞機能制御2009
- Author(s)
  齊藤泰之, 他
- Organizer
  第18回内毒素・LPS研究会
- Place of Presentation
  東京大学
- Year and Date
  2009-06-20
- Data Source
  KAKENHI-PROJECT-21790936
[Presentation] CD47-SIRPαシグナル系による樹状細胞機能制御2009
- Author(s)
  齊藤泰之, 他
- Organizer
  第18回内毒素・LPS研究会
- Place of Presentation
  東京大学(東京都)
- Year and Date
  2009-06-20
- Data Source
  KAKENHI-PROJECT-21790936
[Presentation] Essenntial roles of the CD47-SIRPα signaling for homeostasis of lymphoid tissue dendritic cells2009
- Author(s)
  齊藤泰之, et al.
- Organizer
  The First International Kishimoto Fundation Symposium
- Place of Presentation
  大阪国際会議場
- Data Source
  KAKENHI-PROJECT-21790936
[Presentation] CD47-SIRPαシグナル系によるリンパ組織内樹状細胞の恒常性の制御2009
- Author(s)
  齊藤泰之, 他
- Organizer
  第71回日本血液学会
- Place of Presentation
  京都国際会議場
- Data Source
  KAKENHI-PROJECT-21790936
[Presentation] CD47-SIRPαシグナル系による樹状細胞の恒常性の制御2009
- Author(s)
  齊藤泰之, 他
- Organizer
  第4回日本プロテインホスファターゼ研究会
- Place of Presentation
  熊本大学(熊本県)
- Data Source
  KAKENHI-PROJECT-21790936
[Presentation] Defective development of dendritic cells in SHPS-1 mutant mice2008
- Author(s)
  Saito, Y., et al.
- Organizer
  第8回国際プロテインボスファターゼカンファレンス
- Place of Presentation
  前橋テルサ(前橋
- Data Source
  KAKENHI-PROJECT-20890034
[Presentation] SHPS-1は樹状細胞の恒常性に重要である2008
- Author(s)
  齊藤泰之、他
- Organizer
  第38回日本免疫学会総会・学術集会
- Place of Presentation
  京都国際会館(京都)
- Data Source
  KAKENHI-PROJECT-20890034
[Presentation] Essential roles of SHPS-1 in homeostasis of dendritic cells2008
- Author(s)
  Saito, Y., et al
- Organizer
  第10回国際樹状細胞シンポジゥム
- Place of Presentation
  神戸国際会議場(神戸)
- Data Source
  KAKENHI-PROJECT-20890034
[Presentation] Functinal analysis of protein tyrosine phosphatase Shp2 in post-mitotic neurons
- Author(s)
  Shinya Kusakari, Fumihito Saitow, Miho Hashimoato, Yasunori Matsuzaki , Takenori Kotani, Yoji Murata, Hirokazu Hirai, Hidenori Suzuki, Takashi Matozaki, Hiroshi Ohnishi
- Organizer
  第11回プロテインホスファターゼ国際カンファレンス
- Place of Presentation
  東北大学医学部艮陵会館（宮城県・仙台市）
- Year and Date
  2014-11-12 – 2014-11-14
- Data Source
  KAKENHI-PROJECT-26291022
[Presentation] 樹状細胞及び二次リンパ組織の恒常維持におけるSIRPαの役割
- Author(s)
  鷲尾健、小谷武徳、レスパティカダトゥ、村田陽二、齊藤泰之、金子和光、岡澤秀樹、大西浩史、福永淳、錦織千佳子、的崎尚
- Organizer
  第13回生体機能研究会
- Place of Presentation
  ホテルパーク /岐阜長良川温泉（岐阜県・岐阜市）
- Year and Date
  2014-07-18 – 2014-07-19
- Data Source
  KAKENHI-PROJECT-26291022
[Presentation] Roles of protein tｙrosine phosphatases in homeostasis of intestinal epithelium
- Author(s)
  Takashi Matozaki, Yoji Murata, Takenori Kotani, Yasuyuki Saito
- Organizer
  第11回プロテインホスファターゼ国際カンファレンス
- Place of Presentation
  東北大学医学部艮陵会館（宮城県・仙台市）
- Year and Date
  2014-11-12 – 2014-11-14
- Data Source
  KAKENHI-PROJECT-26291022
[Presentation] Essential role of SIRPα on dendritic ｃells in organization and homeostasis of the spleen
- Author(s)
  Ken Washio, Takenori Kotani, Datu Respatika, Yoji Murata, Yasuyuki Saito, Hideki Okazawa, Hiroshi Ohnishi, Atsushi Fukunaga, Chikako Nishigori, Takashi Matozaki
- Organizer
  第43回日本免疫学会学術集会
- Place of Presentation
  国立京都国際会館（京都府・京都市）
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PROJECT-26291022
[Presentation] Functional Analysis of protein tyrosine phosphatase Shp2 in the adult forebrain neurons
- Author(s)
  Hiroshi Ohnishi, Shinya Kusakari, Fumihito Saitow, Miho Hashimoto, Yasunori Matsuzaki, Takenori Kotani, Yoji Murata, Hirokazu Hirai, Hidenori Suzuki, Takashi Matozaki
- Organizer
  第37回日本神経科学大会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2014-09-11 – 2014-09-13
- Data Source
  KAKENHI-PROJECT-26291022
[Presentation] 細胞間コミュニケーションシステムCD47-SIRPα系による血液・免疫系の制御 / Regulation by CD47-SIRPα signaling of hematopoietic and immune systems
- Author(s)
  小谷武徳、鷲尾健、ダトゥレスパティカ、村田陽二、齊藤泰之、的崎尚
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-26291022

1. Matozaki Takashi (80252782)

# of Collaborated Projects: 1 results

# of Collaborated Products: 25 results
2. OHNISHI Hiroshi (70334125)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
3. MURATA Yoji (60400735)

# of Collaborated Projects: 1 results

# of Collaborated Products: 27 results
4. KOTANI Takenori (40455960)

# of Collaborated Projects: 1 results

# of Collaborated Products: 24 results
5. NARUSE Masae

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. HIROMURA Keiju

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 岡澤秀樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 伊藤光宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 菅波孝祥

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 金子和光

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 宮坂昌之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

SAITO Yasuyuki 齊藤 泰之

Research Projects

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Co-Researchers

Molecular basis for the regulation of dendritic ell and mature T cell survivalPrincipal Investigator

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Development of a novel lymphoma PDX model using humanized micePrincipal Investigator

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Regulation of dendritic cells and lymphoid tissues by CD47-SIRPalpha signalingPrincipal Investigator

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Regulation of the immunological function by the CD47-SIRP alpha signaling systemPrincipal Investigator

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Molecular basis of the CD47-SIRP alpha signaling system in the regulation of physiological function

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The role of SHPS-1 in dendritic cell-mediated autoimmune diseasesPrincipal Investigator

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CD47ーSHPSー1系による自己免疫疾患の新たな制御メカニズムの解明Principal Investigator

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[Book] Encyclopedia of Signaling Molecules: Sirpa2017

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[Book] Encyclopedia of Signaling Molecules: PTPRH2017

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[Book] Encyclopedia of Signaling Molecules: Tyrosine-Protein Phosphatase Nonreceptor Type 11 (PTPN11)2017

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[Journal Article] Utility of the refined EBMT diagnostic and severity criteria 2023 for sinusoidal obstruction syndrome/veno-occlusive disease2024

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[Journal Article] Editorial: The therapeutic inhibition of macrophage checkpoints2024

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[Journal Article] Enhancing anti-EGFRvIII CAR T cell therapy against glioblastoma with a paracrine SIRPγ-derived CD47 blocker2024

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[Journal Article] Analysis of B‐cell receptor repertoire to evaluate immunogenicity of monovalent Omicron XBB.1.5 mRNA vaccines2024

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SAITO Yasuyuki 齊藤泰之