Nakayama Hironao 中山寛尚

… Alternative Names

NAKAYAMA HIROINAO 中山寛尚

中山寛尚ナカヤマヒロナオ

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Researcher Number	40512132
Other IDs	https://orcid.org/0000-0002-9371-2650
Affiliation (Current)	2025: 広島国際大学, 保健医療学部, 准教授
Affiliation (based on the past Project Information) *help	2022 – 2024: 広島国際大学, 保健医療学部, 准教授 2017 – 2021: 広島国際大学, 保健医療学部, 講師 2015 – 2017: 愛媛大学, プロテオサイエンスセンター, 助教 2011: Ehime University, 医学部, 研究員
Review Section/Research Field	Principal Investigator Basic Section 56010:Neurosurgery-related / Neurosurgery / Dermatology Except Principal Investigator General medical chemistry / General surgery
Keywords	Principal Investigator 髄芽腫 / 軸索誘導因子 / 転移 / ネトリン / 癌幹細胞 / 血管新生 / netrin-1 / ニューロピリン / 上皮間葉転換 / Shh / netrin … More Except Principal Investigator … More ゆらぎ / proHB-EGF / エクトドメイン・シェディング / ADAM / シェディング / proamphiregulin / ユビキチンE3リガーゼシ / cullin3 / アクチンダイナミクス / エクトドメイン・シェディング” / Amphiregulin / 膜型細胞増殖因子 / RhoA / CUL3 / amphiregulin / EGFファミリー / 乳がん細胞 / がん細胞の不均一性 / mTOR / セマフォリン３F / 血管新生 / 乳癌 / 転移 / セマフォリン / 軸索誘導因子 / 細胞形質転換 / がん細胞不均一性 Less

高転移型髄芽腫抑制因子セマフォリンペプチドの開発とその応用Principal Investigator
- Principal Investigator
  
  中山寛尚
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Hiroshima International University
軸索誘導因子Netrin-1を標的とした高転移型Group3髄芽腫治療薬の開発Principal Investigator
- Principal Investigator
  
  中山寛尚
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Hiroshima International University
Netrin-1 as a novel therapeutic target of medulloblastomaPrincipal Investigator
- Principal Investigator
  
  Nakayama Hironao
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Hiroshima International University
Semaphorin 3F inhibits breast tumor angiogenesis and metastasis via Akt-mTOR pathway.
- Principal Investigator
  
  Kamei Yoshiaki
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Ehime University
Netrin-1 as a novel therapeutic target of medulloblastomaPrincipal Investigator
- Principal Investigator
  
  Nakayama Hironao
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurosurgery
- Research Institution
  Hiroshima International University
  Ehime University
Fluctuation of ectodomain shedding and the emersion of cancer cell heterogeneity
- Principal Investigator
  
  Higashiyama Shigeki
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General medical chemistry
- Research Institution
  Ehime University
軸策誘導因子Netrin-1を標的にした新規髄芽細胞腫瘍治療法の開発Principal Investigator
- Principal Investigator
  
  中山寛尚
- Project Period (FY)
  2015
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Neurosurgery
- Research Institution
  Ehime University
Study on the fluctuation of ectodomain shedding and its application to predict cancer cell dynamics
- Principal Investigator
  
  HIGASHIYAMA SHIGEKI
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General medical chemistry
- Research Institution
  Ehime University
EGFファミリー分子のmRNA安定化機構解析とその応用Principal Investigator
- Principal Investigator
  
  中山寛尚
- Project Period (FY)
  2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Dermatology
- Research Institution
  Ehime University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016

All Journal Article Presentation

[Journal Article] 血管内皮細胞におけるストレス応答性miR10bの機能解析2024
- Author(s)
  中原正子，中山寛尚
- Journal Title
  
  医療工学雑誌
  
  Volume: 18 Pages: 1-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09192
[Journal Article] ゲノム編集技術CRISPR/Cas9を用いたトラスツズマブ耐性乳癌細胞株の作成とその評価2022
- Author(s)
  松木依理奈，中山寛尚
- Journal Title
  
  医療工学雑誌
  
  Volume: 16 Pages: 13-13
- NAID
  120007193662
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09192
[Journal Article] ゲノム編集技術CRISPR/Cas9を用いたトラスツズマブ耐性乳癌細胞株の作成とその評価2022
- Author(s)
  松木依理奈，中山寛尚
- Journal Title
  
  医療工学雑誌
  
  Volume: 16 Pages: 13-13
- NAID
  120007193662
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08984
[Journal Article] Inactivation of axon guidance molecule netrin-1 in human colorectal cancer by an epigenetic mechanism2022
- Author(s)
  Nakayama Hironao、Ohnuki Hidetaka、Nakahara Masako、Nishida-Fukuda Hisayo、Sakaue Tomohisa、Fukuda Shinji、Higashiyama Shigeki、Doi Yuki、Mitsuyoshi Masahiro、Okimoto Takashi、Tosato Giovanna、Kusumoto Chiaki
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: - Pages: 146-150
- DOI
  10.1016/j.bbrc.2022.04.069
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08574, KAKENHI-PROJECT-21K07448, KAKENHI-PROJECT-21K09192
[Journal Article] Functionally confirmed compound heterozygous ADAM17 missense loss-of-function variants cause neonatal inflammatory skin and bowel disease 12021
- Author(s)
  Imoto I, Saito M, Suga K, Kohmoto T, Otsu M, Horiuchi K, Nakayama H, Higashiyama S, Sugimoto M, Sasaki A, Homma Y, Shono M, Nakagawa R, Hayabuchi Y, Tange S, Kagami S, Masuda K
- Journal Title
  
  Scientific reports
  
  Volume: 11 Issue: 1 Pages: 9552-9552
- DOI
  10.1038/s41598-021-89063-0
- NAID
  120007188413
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07910, KAKENHI-PROJECT-18K08984, KAKENHI-PROJECT-19K08279, KAKENHI-PROJECT-18H02894, KAKENHI-PROJECT-21K07971, KAKENHI-PROJECT-21K09192
[Journal Article] Protective Effect of Ferulic Acid against Hydrogen Peroxide Induced Apoptosis in PC12 Cells2020
- Author(s)
  Nakayama Hironao、Nakahara Masako、Matsugi Erina、Soda Midori、Hattori Tomoka、Hara Koki、Usami Ayuki、Kusumoto Chiaki、Higashiyama Shigeki、Kitaichi Kiyoyuki
- Journal Title
  
  Molecules
  
  Volume: 26 Issue: 1 Pages: 90-90
- DOI
  10.3390/molecules26010090
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08984
[Journal Article] Anosmin-1 activates vascular endothelial growth factor receptor and its related signaling pathway for olfactory bulb angiogenesis2020
- Author(s)
  Matsushima Shoko、Shimizu Akio、Kondo Manami、Asano Hirotsugu、Ueno Nobuhiro、Nakayama Hironao、Sato Naoko、Komeno Masahiro、Ogita Hisakazu、Kurokawa-Seo Misuzu
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 188-188
- DOI
  10.1038/s41598-019-57040-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08984, KAKENHI-PROJECT-17F17418, KAKENHI-PROJECT-17K08627, KAKENHI-PROJECT-17K08657, KAKENHI-PROJECT-16H06276
[Journal Article] Cullin 3 regulates ADAMs-mediated ectodomain shedding of amphiregulin2018
- Author(s)
  Nakayama Hironao、Sakaue Tomohisa、Maekawa Masashi、Fujisaki Ayako、Higashiyama Shigeki
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 499 Issue: 1 Pages: 17-23
- DOI
  10.1016/j.bbrc.2018.03.097
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K15221, KAKENHI-PROJECT-16K18421, KAKENHI-PROJECT-16K19038, KAKENHI-PROJECT-16K20013, KAKENHI-PROJECT-18K07234, KAKENHI-PROJECT-16H04698
[Journal Article] Semaphorin 3F and Netrin-1: The Novel Function as a Regulator of Tumor Microenvironment2018
- Author(s)
  Nakayama Hironao、Kusumoto Chiaki、Nakahara Masako、Fujiwara Akira、Higashiyama Shigeki
- Journal Title
  
  Frontiers in Physiology
  
  Volume: 9
- DOI
  10.3389/fphys.2018.01662
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08984
[Journal Article] Novel function of axon guidance molecule as a regulator of tumor microenvironment2017
- Author(s)
  Nakayama H, Higashiyama S.
- Journal Title
  
  Folia Pharmacologica Japonica
  
  Volume: 150 Issue: 6 Pages: 286-292
- DOI
  10.1254/fpj.150.286
- NAID
  130006247551
- ISSN
  0015-5691, 1347-8397
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K20013
[Journal Article] Both Autocrine Signaling and Paracrine Signaling of HB-EGF Enhance Ocular NeovascularizationHighlights2017
- Author(s)
  Inoue Yuki、Shimazawa Masamitsu、Nakamura Shinsuke、Takata Shinsuke、Hashimoto Yuhei、Izawa Hiroshi、Masuda Tomomi、Tsuruma Kazuhiro、Sakaue Tomohisa、Nakayama Hironao、Higashiyama Shigeki、Hara Hideaki
- Journal Title
  
  Arteriosclerosis, Thrombosis, and Vascular Biology
  
  Volume: 38 Issue: 1 Pages: 174-185
- DOI
  10.1161/atvbaha.117.310337
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K11325, KAKENHI-PROJECT-15J07670, KAKENHI-PROJECT-16J11563, KAKENHI-PROJECT-16K20013
[Journal Article] Downregulation of ANP32B exerts anti-apoptotic effects in hepatocellular carcinoma.2017
- Author(s)
  Ohno Y, Koizumi M, Nakayama H, Watanabe T, Hirooka M, Tokumoto Y, Kuroda T, Abe M, Fukuda S, Higashiyama S, Kumagi T, Hiasa Y.
- Journal Title
  
  PLoS One.
  
  Volume: 12 Issue: 5 Pages: 0177343-0177343
- DOI
  10.1371/journal.pone.0177343
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09006, KAKENHI-PROJECT-16K19349, KAKENHI-PROJECT-16K19350, KAKENHI-PROJECT-16K20013
[Journal Article] Prospect of divergent roles for the CUL3 system in vascular endothelial cell function and angiogenesis2017
- Author(s)
  Sakaue Tomohisa、Maekawa Masashi、Nakayama Hironao、Higashiyama Shigeki
- Journal Title
  
  The Journal of Biochemistry
  
  Volume: 162 Pages: 237-245
- DOI
  10.1093/jb/mvx051
- NAID
  40021380486
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H04698, KAKENHI-PROJECT-16K18421, KAKENHI-PROJECT-16K19038, KAKENHI-PROJECT-16K20013
[Journal Article] Ectodomain Shedding of Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE-1) is induced by VEGF-A.2016
- Author(s)
  Nishida-Fukuda H, Araki R, Shudou M, Okazaki H, Tomono Y, Nakayama H, Fukuda S, Sakaue T, Shirakata Y, Sayama K, Hashimoto K, Detmar M, Higashiyama S, Hirakawa S.
- Journal Title
  
  J Biol Chem.
  
  Volume: 291 Issue: 20 Pages: 10490-10490
- DOI
  10.1074/jbc.m115.683201
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08308, KAKENHI-PROJECT-16K15221
[Journal Article] Reversible interconversion and maintenance of mammary epithelial cell characteristics by the ligand-regulated EGFR system.2016
- Author(s)
  Fukuda S, Nishida-Fukuda H, Nanba D, Nakashiro K, Nakayama H, Kubota H, Higashiyama S.
- Journal Title
  
  Sci Rep.
  
  Volume: 6 Issue: 1 Pages: 20209-20209
- DOI
  10.1038/srep20209
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08308, KAKENHI-PROJECT-26461660, KAKENHI-PROJECT-26670143
[Presentation] 軸索誘導因子は“がん微小環境制御因子”として機能する.2023
- Author(s)
  中山寛尚
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-21K09192
[Presentation] Netrin-1遺伝子のエピジェネティック制御解析と大腸癌バイオマーカーへの応用2022
- Author(s)
  中山寛尚，中原正子，楠本智章
- Organizer
  第95回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-21K09192
[Presentation] 大腸癌におけるnetrin-1遺伝子のエピジェネティック制御解析2022
- Author(s)
  鈴川萌，中原正子，楠本智章，中山寛尚
- Organizer
  第16回日本臨床検査学教育学会
- Data Source
  KAKENHI-PROJECT-21K09192
[Presentation] 大腸癌における軸索誘導因子netrin-1の発現解析2022
- Author(s)
  Hironao Nakayama, Hidetaka Ohnuki, Masako Nakahara, Hisayo Nishida-Fukuda, Tomohisa Sakaue, Shinji Fukuda, Shigeki Higashiyama, Yuki Doi, Masahiro Mitsuyoshi, Takashi Okimoto, Giovanna Tosato, and Chiaki Kusumoto
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K09192
[Presentation] 新規大腸癌バイオマーカーとしての軸索誘導因子netrin-1の有用性評価2022
- Author(s)
  佐野好実，中山寛尚
- Organizer
  第55回中四国支部医学検査学会
- Data Source
  KAKENHI-PROJECT-21K09192
[Presentation] 軸索誘導因子netrin-1を標的とした新規大腸癌バイオマーカーの開発2022
- Author(s)
  松崎実歩，中原正子，楠本智章，中山寛尚
- Organizer
  第16回日本臨床検査学教育学会
- Data Source
  KAKENHI-PROJECT-21K09192
[Presentation] セマフォリン受容体NRP2アイソフォームの機能解析2021
- Author(s)
  松木依理奈，中原正子，楠本智章，中山寛尚
- Organizer
  第15回日本臨床検査学教育学会
- Data Source
  KAKENHI-PROJECT-18K08984
[Presentation] mTOR阻害剤評価のための分子標的薬耐性乳癌細胞株の作製2021
- Author(s)
  松木依理奈，中原正子，楠本智章，中山寛尚
- Organizer
  日本医療検査科学会第53回大会
- Data Source
  KAKENHI-PROJECT-21K09192
[Presentation] 遺伝子編集技術CRISPR/Cas9を用いたトラスツズマブ耐性乳癌細胞株の作製と解析2021
- Author(s)
  原翔一，森岡海，松木依理奈，長島大輝，中原正子，楠本智章，中山寛尚
- Organizer
  第15回日本臨床検査学教育学会
- Data Source
  KAKENHI-PROJECT-21K09192
[Presentation] 遺伝子編集技術CRISPR/Cas9を用いたトラスツズマブ耐性乳癌細胞株の作製と解析2021
- Author(s)
  原翔一，森岡海，松木依理奈，長島大輝，中原正子，楠本智章，中山寛尚
- Organizer
  第15回日本臨床検査学教育学会
- Data Source
  KAKENHI-PROJECT-18K08984
[Presentation] セマフォリン受容体NRP2アイソフォームの機能解析2021
- Author(s)
  松木依理奈，中原正子，楠本智章，中山寛尚
- Organizer
  第15回日本臨床検査学教育学会
- Data Source
  KAKENHI-PROJECT-21K09192
[Presentation] 経口摂取されたフェルラ酸の生体内挙動に関する研究2021
- Author(s)
  宇佐美歩樹，原　亘輝，橋本桂樹，服部友香，曽田　翠，中山寛尚，村瀬仁章，北市清幸
- Organizer
  第12回岐阜薬科大学機能性健康食品研究講演会
- Data Source
  KAKENHI-PROJECT-18K08984
[Presentation] mTOR阻害剤評価のための分子標的薬耐性乳癌細胞株の作製2021
- Author(s)
  松木依理奈，中原正子，楠本智章，中山寛尚
- Organizer
  日本医療検査科学会第53回大会
- Data Source
  KAKENHI-PROJECT-18K08984
[Presentation] 経口摂取されたフェルラ酸の生体内挙動に関する研究2021
- Author(s)
  宇佐美歩樹，原　亘輝，橋本桂樹，服部友香，曽田　翠，中山寛尚，村瀬仁章，北市清幸
- Organizer
  第12回岐阜薬科大学機能性健康食品研究講演会
- Data Source
  KAKENHI-PROJECT-21K09192
[Presentation] フェルラ酸による神経細胞保護作用の分子メカニズム解析2020
- Author(s)
  中原正子，松木依理奈，楠本智章，曽田翠，原亘輝，宇佐美歩樹，服部友香，東山繁樹，北市清幸，中山寛尚
- Organizer
  第61回日本生化学会中国・四国支部例会
- Data Source
  KAKENHI-PROJECT-18K08984
[Presentation] PTEN欠損乳癌細胞における軸索誘導因子セマフォリン３Fシグナル解析2020
- Author(s)
  松木依理奈，中原正子，楠本智章，東山繁樹，中山寛尚
- Organizer
  第61回日本生化学会中国・四国支部例会
- Data Source
  KAKENHI-PROJECT-18K08984
[Presentation] フェルラ酸の生体内挙動と脳機能への影響2020
- Author(s)
  北市清幸，中山寛尚
- Organizer
  第11回フェルラ酸研究会
- Data Source
  KAKENHI-PROJECT-18K08984
[Presentation] Semaphorin 3F inhibits breast tumor angiogenesis and metastasis via Akt-mTOR pathway.2020
- Author(s)
  Hironao Nakayama, Akari Murakami, Yoshiaki Kamei, Yasutsugu Takada and Shigeki Higashiyama
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K08984
[Presentation] Netrin-1シグナルに着目した髄芽腫転移メカニズム解析2019
- Author(s)
  8.後藤大尚，尾野達郎，中原正子，楠本智章，藤原章，東山繁樹，中山寛尚
- Organizer
  第14回日本臨床検査学教育学会
- Data Source
  KAKENHI-PROJECT-18K08984
[Presentation] Semaphorin 3F inhibits breast tumor angiogenesis and metastasis via Akt-mTOR pathway.2018
- Author(s)
  Hironao Nakayama, Ayumi Nakazawa, Natsuki Sawatari, Akari Murakami, Hisayo Nishida-Fukuda, Yoshiaki Kamei, Yasutsugu Takada and Shigeki Higashiyama
- Organizer
  International Vascular Biology Meeting 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10553
[Presentation] Semaphorin 3F inhibits breast tumor angiogenesis and metastasis via Akt-mTOR pathway.2017
- Author(s)
  Hironao Nakayama, Akari Murakami, Hisayo Nishida-Fukuda, Yoshiaki Kamei, Yasutsugu Takada and Shigeki Higashiyama.
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K10553
[Presentation] セマフォリン3Fは乳癌の血管新生と転移を抑制する.2017
- Author(s)
  中山寛尚, 村上朱里, 福田尚代, 亀井義明, 高田泰次, 東山繁樹.
- Organizer
  生命科学系学会合同年次大会　第90回日本生化学会
- Data Source
  KAKENHI-PROJECT-16K20013
[Presentation] セマフォリン3Fは乳癌の血管新生と転移を抑制する.2017
- Author(s)
  中山寛尚, 村上朱里, 福田尚代, 亀井義明, 高田泰次, 東山繁樹.
- Organizer
  生命科学系学会合同年次大会　第90回日本生化学会
- Data Source
  KAKENHI-PROJECT-17K10553
[Presentation] Semaphorin 3F inhibits breast tumor angiogenesis and metastasis via Akt-mTOR pathway.2017
- Author(s)
  Hironao Nakayama, Akari Murakami, Hisayo Nishida-Fukuda, Yoshiaki Kamei, Yasutsugu Takada and Shigeki Higashiyama.
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K20013
[Presentation] EGFファミリー分子のshedding特性解析2016
- Author(s)
  中山寛尚, 坂上倫久, 前川大志, 藤崎亜耶子, 東山繁樹
- Organizer
  第57回日本生化学会中国・四国支部例会
- Place of Presentation
  高知
- Year and Date
  2016-05-27
- Data Source
  KAKENHI-PROJECT-16K15221

1. HIGASHIYAMA SHIGEKI (60202272)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
2. FUKUDA SHINJI (70398238)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
3. NANBA DAISUKE (10380255)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. Kamei Yoshiaki (90623702)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
5. HARA Hideaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. TSURUMA Kazuhiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. Sakaue Tomohisa

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. Maekawa Masashi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. Fukuda Hisayo

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
10. 増田清士

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 日浅陽一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Nakayama Hironao 中山 寛尚

NAKAYAMA HIROINAO 中山 寛尚

中山 寛尚 ナカヤマ ヒロナオ

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Co-Researchers

高転移型髄芽腫抑制因子セマフォリンペプチドの開発とその応用Principal Investigator

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軸索誘導因子Netrin-1を標的とした高転移型Group3髄芽腫治療薬の開発Principal Investigator

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Netrin-1 as a novel therapeutic target of medulloblastomaPrincipal Investigator

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Semaphorin 3F inhibits breast tumor angiogenesis and metastasis via Akt-mTOR pathway.

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Netrin-1 as a novel therapeutic target of medulloblastomaPrincipal Investigator

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Fluctuation of ectodomain shedding and the emersion of cancer cell heterogeneity

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軸策誘導因子Netrin-1を標的にした新規髄芽細胞腫瘍治療法の開発Principal Investigator

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Study on the fluctuation of ectodomain shedding and its application to predict cancer cell dynamics

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EGFファミリー分子のmRNA安定化機構解析とその応用Principal Investigator

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[Journal Article] 血管内皮細胞におけるストレス応答性miR10bの機能解析2024

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[Journal Article] ゲノム編集技術CRISPR/Cas9を用いたトラスツズマブ耐性乳癌細胞株の作成とその評価2022

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NAID

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[Journal Article] ゲノム編集技術CRISPR/Cas9を用いたトラスツズマブ耐性乳癌細胞株の作成とその評価2022

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NAID

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[Journal Article] Inactivation of axon guidance molecule netrin-1 in human colorectal cancer by an epigenetic mechanism2022

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[Journal Article] Functionally confirmed compound heterozygous ADAM17 missense loss-of-function variants cause neonatal inflammatory skin and bowel disease 12021

Nakayama Hironao 中山寛尚

NAKAYAMA HIROINAO 中山寛尚

中山寛尚ナカヤマヒロナオ