Jono Hirofumi 城野博史

… Alternative Names

JONO Hirofumi 城野博史

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Researcher Number	40515483
Other IDs
Affiliation (Current)	2025: 熊本大学, 病院, 教授
Affiliation (based on the past Project Information) *help	2019 – 2024: 熊本大学, 病院, 准教授 2012 – 2018: 熊本大学, 医学部附属病院, 准教授 2011: 熊本大学, 生命科学研究部, 講師 2009 – 2011: 熊本大学, 大学院・生命科学研究部, 講師 2009: 熊本大, 講師 2008: Kumamoto University, 大学院・医学薬学研究部, 講師
Review Section/Research Field	Principal Investigator Basic Section 47060:Clinical pharmacy-related / Medical pharmacy / Biological pharmacy / Pharmaceutical Sciences and related fields Except Principal Investigator Basic Section 47060:Clinical pharmacy-related / Medical pharmacy / Laboratory medicine / Medium-sized Section 7:Economics, business administration, and related fields / Medium-sized Section 90:Biomedical engineering and related fields / Applied pharmacology / Neurology
Keywords	Principal Investigator CYLD / 家族性アミロイドポリニューロパチー / 個別化医療 / アミロイドーシス / 高機能性遺伝子キャリア / 薬剤感受性 / 肺線維症 / 効果予測マーカー / 分子診断 / 分子標的治療 … More / 分子標的治療薬 / 樹状高分子デンドリマー / RNAi医薬 / 癌 / 分子標的薬 / シグナル伝達 / 予後予測因子 / 個別医療 / 脱ユビキチン化酵素 / 腫瘍抑制遺伝子 / TGF / 慢性炎症 / 細菌感染症 / 遺伝性疾患 / 脱ユピキチン化酵素 / 慢性閉塞性肺疾患 … More Except Principal Investigator トランスサイレチン / 家族性アミロイドポリニューロパチー / 硫酸転移酵素 / 尿毒症物質 / アミロイドーシス / シクロデキストリン / ゲノム編集 / 腎障害 / インドキシル硫酸 / 急性腎障害 / 代謝スクリーニング / 遺伝子変異 / 肝細胞 / FAP / iPS細胞 / 超分子 / ロタキサン / パレート効率性 / 費用対効果 / 抗がん剤 / 医療経済学 / 持続可能性 / MSK-IMPACT / モバイルヘルス / 免疫チェックポイント阻害剤 / パレート最適 / ヘルスケアビジネス / イノベーション / HTA / 精神疾患 / 機械学習 / 薬理ゲノム学 / ファーマコメトリクス / 精神神経薬理学 / 精密医療 / CRISPRA Cas9 mRNA / 遺伝性難病 / ３元複合体 / mRNA / デンドリマー / 結合体 / 家族性アミロイドポリニューロパチー / 肝臓特異的非ウイルスベクター / ガイドRNA / アミロイドポリニューロパチー / 肝臓ターゲティング / PAMAMデンドリマー / 非ウイルスベクター / CRISPR mRNA / 慢性腎臓病 / 治療薬開発 / 活性酸素種 / シスプラチン腎症 / 人工多能性幹細胞 / ヒト肝細胞 / iPS / 代謝スクリーニング系 / 腎臓病 / 薬物動態 / ALアミロイドーシス / レーザーマイクロダイセクション / ＡＬアミロイドーシス / ポリニューロパチー家族性アミロイド / マススペクトロメトリー / アミロイド原因蛋白質 / LC-MS/MS / 臨床検査医学 / エピトープ / 自己抗体 / ミスフォールディング / ミスフォールディング病 / 移植 / 線維芽細胞 / 遺伝子治療 / 肝細胞置換療法 / 点変異修復 Less

細胞環境応答型超分子キャリアを用いたアルツハイマー病ゲノム編集治療戦略の構築
- Principal Investigator
  
  本山敬一
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Kumamoto University
Establishing novel molecular-targeted cancer therapies based on tumor suppressor CYLD dependent tumor transformationPrincipal Investigator
- Principal Investigator
  
  城野博史
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Kumamoto University
Development of innovative drug dosage regimens compatible with diverse treatment responsiveness in depression and schizophrenia
- Principal Investigator
  
  Saruwatari Junji
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Kumamoto University
Empirical study on Pareto efficiency related to industry, medical care and insurance in anti-cancer drug treatment
- Principal Investigator
  
  Kota Kodama
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 7:Economics, business administration, and related fields
- Research Institution
  Ritsumeikan University
Development of non-viral vector to realize treatment of hereditary disease using genome editing RNA technology
- Principal Investigator
  
  Hidetoshi Arima
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  Daiichi University, College of Pharmaceutical Sciences
Establishing novel molecular-targeted cancer therapies based on molecular diagnostics focusing on prognostic factor CYLDPrincipal Investigator
- Principal Investigator
  
  Jono Hirofumi
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Kumamoto University
Potential use of multifunctional polyamidoamine Dendrimer for curative treatments of intractable amyloidosesPrincipal Investigator
- Principal Investigator
  
  JONO Hirofumi
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Research Field
  
  Pharmaceutical Sciences and related fields
- Research Institution
  Kumamoto University
Search for uremia suppressive therapeutics based on investigation on role of sulfate-conjugated uremic solutes in development and pregoression of kidney injury
- Principal Investigator
  
  SAITO HIDEYUKI
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied pharmacology
- Research Institution
  Kumamoto University
Development of novel multi-target drugs for intractable amyloidosesPrincipal Investigator
- Principal Investigator
  
  Jono Hirofumi
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Medical pharmacy
- Research Institution
  Kumamoto University
Elucidating clinical significance of CYLD down-regulation for establishing individualized cancer therapyPrincipal Investigator
- Principal Investigator
  
  Jono Hirofumi
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Medical pharmacy
- Research Institution
  Kumamoto University
Development of renoprotective and uremia therapeutic drug seeds based on inhibition of hepatic production of sulfate-conjugated uremic solutes
- Principal Investigator
  
  Saito Hideyuki
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Medical pharmacy
- Research Institution
  Kumamoto University
Establishment of hepatocyte model from induced pluripotent stem (iPS) cells for exploring uremic toxin production inhibitors
- Principal Investigator
  
  Saito Hideyuki
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Medical pharmacy
- Research Institution
  Kumamoto University
Early diagnosis and analyses of the pathogenesis for amyloidosis with all our previous investigations
- Principal Investigator
  
  ANDO Yukio
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Laboratory medicine
- Research Institution
  Kumamoto University
Analysis of autoantibodies for targeting pathogenesis and therapyof misfolding diseases
- Principal Investigator
  
  ANDO Yukio
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Laboratory medicine
- Research Institution
  Kumamoto University
Novel roles of chronic inflammatory factor CYLD in lung fibrosisPrincipal Investigator
- Principal Investigator
  
  JONO Hirofumi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Kumamoto University
Hepatocyte replacement therapy for familial amybidotic polyneuropathy combining iPS cells and gene-repair therapy
- Principal Investigator
  
  ANDO Yukio
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurology
- Research Institution
  Kumamoto University
Novel roles of CYLD in the molecular pathogenesis of intractable diseasesPrincipal Investigator
- Principal Investigator
  
  JONO Hirofumi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (Start-up)
- Research Field
  
  Biological pharmacy
- Research Institution
  Kumamoto University

[Book] 図解腫瘍薬学2020
- Author(s)
  城野博史、三宅俊介
- Total Pages
  677
- Publisher
  南山堂
- ISBN
  9784525721619
- Data Source
  KAKENHI-PROJECT-18H02591
[Book] 月刊『腎臓内科・泌尿器科』, シスプラチン腎障害－最近の話題2016
- Author(s)
  藤野梨香、城野博史、齋藤秀之
- Total Pages
  518
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-25293040
[Book] Human Serum Albumin2013
- Author(s)
  Jono H, Ando Y
- Total Pages
  510
- Publisher
  崇城大学出版センター
- Data Source
  KAKENHI-PROJECT-24249036
[Book] The proceedings of the XIIIth International Symposium on Amyloidosis, May6-10, 20122013
- Author(s)
  Ihse E, Rapezzi C, Merlini G, Benson MD, Ando Y, Suhr OB, Leone O, Lorenzini M, Quarta CC, Obici L, Lavatelli F, Liepnieks J,Ohshima T, Jono H, Westermark P, Ikeda S-I, Tasaki M, Ueda M
- Total Pages
  496
- Publisher
  GUARD (Groningen unit for Amyloidosisi Reserch & Development)
- Data Source
  KAKENHI-PROJECT-24249036
[Book] 脳機能を反映する血中バイオマーカーの現状と展望(医療と検査機器・試薬、ラボ・サービス、33)2010
- Author(s)
  城野博史、大林光念、安東由喜雄
- Data Source
  KAKENHI-PROJECT-20890167
[Book] Recent Advances in Transthyretin Evolution, Structure, and Biological Functions(論文タイトル)New therapeutic approaches for familial amyloidotic polyneuropathy (FAP)2009
- Author(s)
  Ando Y, Nakamura M, Ueda, M, Jono H (書籍全体の編集者名)Richardoson SJ, Cody V.
- Total Pages
  362
- Publisher
  Springer, Dordrecht Heidelberg London New York
- Data Source
  KAKENHI-PROJECT-21390270
[Book] New Therapeutic Approaches for Familial Amyloidotic Polyneuropathy (FAP) Recent Advances in Transthyretin Evolution(Structure and Biological Functions)2009
- Author(s)
  Ando Y, Nakamura M, Ueda M, Jono H.
- Publisher
  Springer, Chapter
- Data Source
  KAKENHI-PROJECT-20890167
[Book] New Therapeutic Approaches for Familial AmyloidoticPolyneuropathy(FAP) Recent Advances in Transthyretin Evolution, Structure and Biological Functions2009
- Author(s)
  Ando Y, Nakamura M, Ueda M, Jono H
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-21390270
[Book] 季刊腎と骨代謝(β2-ミクログロブリンの分子修飾)2009
- Author(s)
  城野博史、安東由喜雄
- Publisher
  臨床医学出版
- Data Source
  KAKENHI-PROJECT-20890167
[Book] 臨床病理(トランスサイレチン型アミロイドーシスの病態解析と治療)2008
- Author(s)
  安東由喜雄、城野博史
- Publisher
  克誠堂出版
- Data Source
  KAKENHI-PROJECT-20890167
[Journal Article] Wnt/β-catenin signaling is a novel therapeutic target for tumor suppressor CYLD-1silenced glioblastoma cells2023
- Author(s)
  Kanemaru Ayumi、Ito Yuki、Yamaoka Michiko、Shirakawa Yuki、Yonemaru Kou、Miyake Shunsuke、Ando Misaki、Ota Masako、Masuda Takeshi、Mukasa Akitake、Li Jian-Dong、Saito Hideyuki、Hide Takuichiro、Jono Hirofumi
- Journal Title
  
  Oncology Reports
  
  Volume: 50 Issue: 5 Pages: 1-12
- DOI
  10.3892/or.2023.8638
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K15400, KAKENHI-PROJECT-22K20797, KAKENHI-PROJECT-20K09374, KAKENHI-PUBLICLY-22H05546, KAKENHI-PROJECT-23K23867, KAKENHI-PROJECT-23K24047, KAKENHI-PROJECT-23K27345
[Journal Article] Multifunctional Therapeutic Cyclodextrin-Appended Dendrimer Complex for Treatment of Systemic and Localized Amyloidosis2022
- Author(s)
  Inoue M, Higashi T, Hayashi Y, Onodera R, Fujisawa K, Taharabaru T, Yokoyama R, Ouchi K, Misumi Y, Ueda M, Inoue Y, Mizuguchi M, Saito T, Saido TC, Ando Y, Arima H, Motoyama K, Jono H.
- Journal Title
  
  ACS Appl Mater Interfaces
  
  Volume: 14 Issue: 36 Pages: 40599-40611
- DOI
  10.1021/acsami.2c09913
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07528, KAKENHI-PROJECT-19K22972, KAKENHI-PROJECT-21J11627, KAKENHI-PROJECT-23K24245
[Journal Article] Feasibility Study of Dendrimer-Based TTR-CRISPR pDNA Polyplex for Ocular Amyloidosis <i>in Vitro</i>2022
- Author(s)
  Inoue M, Muta K, Mohammed AFA, Onodera R, Higashi T, Ouchi K, Ueda M, Ando Y, Arima H, Jono H, Motoyama K.
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 45 Issue: 11 Pages: 1660-1668
- DOI
  10.1248/bpb.b22-00452
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2022-11-01
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K07528, KAKENHI-PROJECT-19K22972, KAKENHI-PROJECT-21J11627, KAKENHI-PROJECT-23K24245
[Journal Article] The tumour suppressor CYLD is required for clathrin-mediated endocytosis of EGFR and cetuximab-induced apoptosis in head and neck squamous cell carcinoma.2022
- Author(s)
  Liu R, Shinriki S, Maeshiro M, Hirayama M, Jono H, Yoshida R, Nakayama H, Matsui H
- Journal Title
  
  Cancers
  
  Volume: 14 Issue: 1 Pages: 173-173
- DOI
  10.3390/cancers14010173
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10360, KAKENHI-PROJECT-18H02591, KAKENHI-PROJECT-21K08419, KAKENHI-PROJECT-21K21019
[Journal Article] A novel step‐down infusion method of barbiturate therapy: Its safety and effectiveness for intracranial pressure control2021
- Author(s)
  Yamakawa Yukako、Morioka Motohiro、Negoto Tetsuya、Orito Kimihiko、Yoshitomi Munetake、Nakamura Yukihiko、Takeshige Nobuyuki、Yamamoto Masafumi、Takeuchi Yasuharu、Oda Kazutaka、Jono Hirofumi、Saito Hideyuki
- Journal Title
  
  Pharmacology Research & Perspectives
  
  Volume: 9 Issue: 2
- DOI
  10.1002/prp2.719
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04104, KAKENHI-PROJECT-18K08955, KAKENHI-PROJECT-21K09193
[Journal Article] Suppressed Hepatic Production of Indoxyl Sulfate Attenuates Cisplatin-Induced Acute Kidney Injury in Sulfotransferase 1a1-Deficient Mice2021
- Author(s)
  Yabuuchi Nozomi、Hou Huixian、Gunda Nao、Narita Yuki、Jono Hirofumi、Saito Hideyuki
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 22 Issue: 4 Pages: 1764-1764
- DOI
  10.3390/ijms22041764
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04104
[Journal Article] CYLD: a novel stratification marker for malignant tumors2021
- Author(s)
  Shunsuke Miyake, Ayumi Kanemaru, Hideyuki Saito, Hirofumi Jono
- Journal Title
  
  Journal of Asian Association of Schools of Pharmacy
  
  Volume: 10 Pages: 17-22
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02591
[Journal Article] Glioma Cells Acquire Stem-like Characters by Extrinsic Ribosome Stimuli2021
- Author(s)
  Shirakawa Yuki、Ohta Kunimasa、Miyake Shunsuke、Kanemaru Ayumi、Kuwano Akari、Yonemaru Kou、Uchino Shota、Yamaoka Michiko、Ito Yuki、Ito Naofumi、Hide Takuichiro、Shinojima Naoki、Mukasa Akitake、Saito Hideyuki、Jono Hirofumi
- Journal Title
  
  Cells
  
  Volume: 10 Issue: 11 Pages: 2970-2970
- DOI
  10.3390/cells10112970
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02591, KAKENHI-PROJECT-19H03235, KAKENHI-PROJECT-20K09374, KAKENHI-PROJECT-20H03792
[Journal Article] Comparative Study of Constipation Exacerbation by Potassium Binders Using a Loperamide-Induced Constipation Model2020
- Author(s)
  Narita Yuki、Fukumoto Koichi、Fukunaga Masaki、Kondo Yuki、Ishitsuka Yoichi、Jono Hirofumi、Irie Tetsumi、Saito Hideyuki、Kadowaki Daisuke、Hirata Sumio
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 21 Issue: 7 Pages: 2491-2491
- DOI
  10.3390/ijms21072491
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04104, KAKENHI-PROJECT-18K06774
[Journal Article] Relationship between clinicopathological characteristics and CYLD expression in patients with cholesteatoma.2020
- Author(s)
  Miyake S, Miwa T, Yoneda G, Kanemaru A, Saito H, Minoda R, Orita Y, Saito H, Jono H.
- Journal Title
  
  PLoS One
  
  Volume: 15
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02591
[Journal Article] Ribosomal protein S6 promotes stem‐like characters in glioma cells2020
- Author(s)
  Shirakawa Yuki、Hide Takuichiro、Yamaoka Michiko、Ito Yuki、Ito Naofumi、Ohta Kunimasa、Shinojima Naoki、Mukasa Akitake、Saito Hideyuki、Jono Hirofumi
- Journal Title
  
  Cancer Science
  
  Volume: 111 Issue: 6 Pages: 2041-2051
- DOI
  10.1111/cas.14399
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09374, KAKENHI-PROJECT-17H04104, KAKENHI-PROJECT-18H02591, KAKENHI-PROJECT-19H03235, KAKENHI-PROJECT-20H03792
[Journal Article] Continuous high-dose infusion of doripenem in a pneumonia patient infected by carbapenem-resistant Pseudomonas aeruginosa: a case report2019
- Author(s)
  Oda K, Kamohara H, Katanoda T, Hashiguchi Y, Iwamura K, Nosaka K, Jono H, Saito H.
- Journal Title
  
  J Pharm Health Care Sci.
  
  Volume: 5 Pages: 1-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04104
[Journal Article] Establishing individualized medicine for intractable cancer based on clinical molecular pathogenesis　－A novel predictive marker CYLD for molecular targeted therapies－2019
- Author(s)
  Jono H, Saito H
- Journal Title
  
  Proceedings for Annual Meeting of The Japanese Pharmacological Society
  
  Volume: 92 Issue: 0 Pages: 2-S15-4
- DOI
  10.1254/jpssuppl.92.0_2-S15-4
- NAID
  130007813106
- ISSN
  2435-4953
- Language
  Japanese
- Data Source
  KAKENHI-PROJECT-18H02591
[Journal Article] Loss of tumor suppressor CYLD expression triggers cisplatin resistance in oral squamous cell carcinoma.2019
- Author(s)
  Suenaga N, Kuramitsu M, Komure K, Kanemaru A, Takano K, Ozeki K, Nishimura Y, Yoshida R, Nakayama H, Shinriki S, Saito H, Jono H.
- Journal Title
  
  J Mol Sci
  
  Volume: 20 Issue: 20 Pages: 5194-5194
- DOI
  10.3390/ijms20205194
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10360, KAKENHI-PROJECT-17H04104, KAKENHI-PROJECT-18H02591
[Journal Article] Edoxaban Exerts Antioxidant Effects Through FXa Inhibition and Direct Radical-Scavenging Activity.2019
- Author(s)
  Narita Y, Hamamura K, Kashiyama M, Utsumi S, Kakizoe Y, Kondo Y, Ishitsuka Y, Jono H, Irie T, Mukoyama M, Saito H, Kadowaki D, Hirata S, Kitamura K.
- Journal Title
  
  Int J Mol Sci.
  
  Volume: 20
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04104
[Journal Article] Development and evaluation of a vancomycin dosing nomogram to achieve the target area under the concentration-time curve. A retrospective study.2019
- Author(s)
  Oda K, Katanoda T, Hashiguchi Y, Kondo S, Narita Y, Iwamura K, Nosaka K, Jono H, Saito H
- Journal Title
  
  J Infect Chemother.
  
  Volume: 26 Pages: 444-450
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04104
[Journal Article] The 2nd Symposium “Current Status of Reverse Translational Research Conducted by Hospital Pharmacists” ～Challenges for Screening of Therapeutic Molecular Target and Personalized Medicine～2019
- Author(s)
  Masuda S, Itoh H, Ikeda R, Jono H
- Journal Title
  
  YAKUGAKU ZASSHI
  
  Volume: 139 Issue: 6 Pages: 899-900
- DOI
  10.1248/yakushi.18-00213-F
- NAID
  130007657107
- ISSN
  0031-6903, 1347-5231
- Year and Date
  2019-06-01
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02591
[Journal Article] Therapeutic Potential of Polyamidoamine Dendrimer for Amyloidogenic Transthyretin Amyloidosis2019
- Author(s)
  Inoue M, Ueda M, Higashi T, Anno T, Fujisawa K, Motoyama K, Mizuguchi M, Ando Y, Jono H, Arima H.
- Journal Title
  
  ACS Chemical Neuroscience
  
  Volume: 印刷中 Issue: 5 Pages: 2584-2590
- DOI
  10.1021/acschemneuro.9b00059
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04841, KAKENHI-PROJECT-17K19498, KAKENHI-PROJECT-19H03565
[Journal Article] In vitro and in vivo siRNA delivery to hepatocyte utilizing ternary complexation of lactosylated dendrimer/cyclodextrin conjugates, siRNA and low-molecular-weight sacran2018
- Author(s)
  Hayashi Yuya、Higashi Taishi、Motoyama Keiichi、Jono Hirofumi、Ando Yukio、Arima Hidetoshi
- Journal Title
  
  International Journal of Biological Macromolecules
  
  Volume: 107 Pages: 1113-1121
- DOI
  10.1016/j.ijbiomac.2017.09.085
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K19498, KAKENHI-PROJECT-15H04841, KAKENHI-PROJECT-17H06970
[Journal Article] Recent Advances in Oligonucleotide-Based Therapy for Transthyretin Amyloidosis: Clinical Impact and Future Prospects2018
- Author(s)
  Hayashi Yuya、Jono Hirofumi
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 41 Issue: 12 Pages: 1737-1744
- DOI
  10.1248/bpb.b18-00625
- NAID
  130007539542
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2018-12-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H06970, KAKENHI-PROJECT-17K19498
[Journal Article] Doxycycline attenuates cisplatin-induced acute kidney injury through pleiotropic effects.2018
- Author(s)
  Nakagawa T, Kakizoe Y, Iwata Y, Miyasato Y, Mizumoto T, Adachi M, Izumi Y, Kuwabara T, Suenaga N, Narita Y, Jono H, Saito H, Kitamura K, Mukoyama M.
- Journal Title
  
  Am J Physiol Renal Physiol.
  
  Volume: 315
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04104
[Journal Article] Establishing Individualized Medicine for Intractable Cancer Based on Clinical Molecular Pathogenesis2018
- Author(s)
  Jono Hirofumi
- Journal Title
  
  YAKUGAKU ZASSHI
  
  Volume: 138 Issue: 4 Pages: 451-455
- DOI
  10.1248/yakushi.17-00207
- NAID
  130006601922
- ISSN
  0031-6903, 1347-5231
- Year and Date
  2018-04-01
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02591
[Journal Article] Establishing Individualized Medicine for Intractable Cancer Based on Clinical Molecular Pathogenesis2018
- Author(s)
  Jono H
- Journal Title
  
  Yakugaku Zasshi
  
  Volume: 138 Pages: 451-455
- NAID
  130006601922
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26713006
[Journal Article] Loss of CYLD promotes cell invasion via ALK5 stabilization in oral squamous cell carcinoma2018
- Author(s)
  Shinriki S, Jono H, Maeshiro M, Nakamura T, Guo J, Li JD, Ueda M, Yoshida R, Shinohara M, Nakayama H, Matsui H, Ando Y.
- Journal Title
  
  Journal of Pathology
  
  Volume: 244 Issue: 3 Pages: 367-379
- DOI
  10.1002/path.5019
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11726, KAKENHI-PROJECT-26713006, KAKENHI-PUBLICLY-17H05649, KAKENHI-PROJECT-15K09318, KAKENHI-PROJECT-15K09478, KAKENHI-PROJECT-15K11296, KAKENHI-PROJECT-18K07502, KAKENHI-PROJECT-18H02591, KAKENHI-PROJECT-18H03005
[Journal Article] A novel central nervous system-penetrating protease inhibitor overcomes human immunodeficiency virus 1 resistance with unprecedented aM to pM potency.2017
- Author(s)
  Aoki M, Hayashi H, Rao KV, Das D, Higashi-Kuwata N, Bulut H, Aoki-Ogata H, Takamatsu Y, Yedidi RS, Davis DA, Hattori SI, Nishida N, Hasegawa K, Takamune N, Nyalapatla PR, Osswald HL, Jono H, Saito H, Yarchoan R, Misumi S, Ghosh AK, Mitsuya H.
- Journal Title
  
  Elife
  
  Volume: 6
- DOI
  10.7554/elife.28020
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19577, KAKENHI-PROJECT-17K15710, KAKENHI-PROJECT-17H04104, KAKENHI-PROJECT-17H04222
[Journal Article] An oncofetal antigen, IMP-3-derived long peptides induce immune responses of both helper T cells and CTLs.2016
- Author(s)
  Hirayama M, Tomita Y, Yuno A, Tsukamoto H, Senju S, Imamura Y, Sayem MA, Irie A, Yoshitake Y, Fukuma D, Shinohara M, Hamada A, Jono H, Yuba E, Kono K, Yoshida K, Tsunoda T, Nakayama H, Nishimura Y
- Journal Title
  
  Oncoimmunology
  
  Volume: 5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26713006
[Journal Article] Long-term outcome of patients with hereditary transthyretin V30M amyloidosis with polyneuropathy after liver transplantation.2016
- Author(s)
  Okumura K, Yamashita T, Masuda T, Misumi Y, Ueda A, Ueda M, Obayashi K, Jono H, Yamashita S, Inomata Y, Ando Y.
- Journal Title
  
  Amyloid
  
  Volume: 23 Issue: 1 Pages: 39-45
- DOI
  10.3109/13506129.2015.1123149
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09318, KAKENHI-PROJECT-15K15006, KAKENHI-PROJECT-15K19184, KAKENHI-PROJECT-15H04841, KAKENHI-PROJECT-26860672, KAKENHI-PROJECT-15K15195, KAKENHI-PROJECT-16K09674
[Journal Article] Long-term outcome of patients with hereditary transthyretin V30M amyloidosis with Polyneuropathy after liver transplantation2016
- Author(s)
  Okumura K, Yamashita T, Masuda T, Misumi Y, Ueda A, Ueda M, Obayashi K, Jono H, Yamashita S, Inomata Y, Ando Y
- Journal Title
  
  Amyloid
  
  Volume: 13 Pages: 1-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K15006
[Journal Article] Nephropreventive Effect of Shikonin on Murine LPS-induced Septic Acute Kidney Injury via Nrf2 Activation with Antioxidative Responses.2016
- Author(s)
  Madoka Kawara, Rika Matsunaga, Yuko Yamamoto, Go Yoneda, Rika Fujino, Hirofumi Jono, Hideyuki Saito.
- Journal Title
  
  J Clin Exp Nephrol
  
  Volume: 1 Issue: 03 Pages: 19-24
- DOI
  10.21767/2472-5056.100019
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25293040
[Journal Article] Indoxyl Sulfate as a Mediator Involved in Dysregulation of Pulmonary Aquaporin-5 in Acute Lung Injury Caused by Acute Kidney Injury.2016
- Author(s)
  Yabuuchi N, Sagata M, Saigo C, Yoneda G, Yamamoto Y, Nomura Y, Nishi K, Fujino R, Jono H, Saito H.
- Journal Title
  
  Int J Mol Sci
  
  Volume: 18 Issue: 1 Pages: 11-11
- DOI
  10.3390/ijms18010011
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25293040
[Journal Article] Sources of variation of transthyretin in healthy subjects in East and Southeast Asia: Clinical and experimental evidence for the effect of alcohol on transthyretin metabolism.2016
- Author(s)
  Jono H, Su Y, Obayashi K, Tanaka Y, Ishiguro A, Nishimura H, Shinriki S, Ueda M, Ikeda K, Yamagata K, Ichihara K, Ando Y; Scientific Committee for the Asia-Pacific Federation of Clinical Biochemistry.
- Journal Title
  
  Clin Chim Acta
  
  Volume: 458 Pages: 240-5
- DOI
  10.1016/j.cca.2016.04.011
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09318, KAKENHI-PROJECT-16H02771, KAKENHI-PROJECT-15H04841, KAKENHI-PROJECT-15K15006, KAKENHI-PROJECT-15K15195, KAKENHI-PROJECT-16H05328
[Journal Article] 悪性腫瘍組織における腫瘍抑制遺伝子CYLD発現消失の臨床的意義2016
- Author(s)
  城野博史
- Journal Title
  
  臨床化学
  
  Volume: 45 Pages: 120-126
- Data Source
  KAKENHI-PROJECT-26713006
[Journal Article] Effect of administration duration of low dose Methotrexate on development of acute kidney injury in rats.2016
- Author(s)
  Li X, Abe E, Yamakawa Y, Yoneda G, Fujino R, Yamashita M, Iida Y, Jono H, Saito H
- Journal Title
  
  Journal of Kidney
  
  Volume: 2 Issue: 3
- DOI
  10.4172/2472-1220.1000130
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25293040
[Journal Article] Novel Antibody for the Treatment of Transthyretin Amyloidosis.2016
- Author(s)
  Hosoi A, Su Y, Torikai M, Jono H, Ishikawa D, Soejima K, Higuchi H, Guo J, Ueda M, Suenaga G, Motokawa H, Ikeda T, Senju S, Nakashima T, Ando Y
- Journal Title
  
  J Biol Chem
  
  Volume: 291 Pages: 25096-25105
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K15006
[Journal Article] Inhibition of insulin amyloid fibril formation by cyclodextrins.2015
- Author(s)
  Kitagawa K, Misumi Y, Ueda M, Hayashi Y, Tasaki M, Obayashi K, Yamashita T, Jono H, Arima H, Ando Y.
- Journal Title
  
  Amyloid
  
  Volume: 22 Issue: 3 Pages: 181-186
- DOI
  10.3109/13506129.2015.1064818
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09318, KAKENHI-PROJECT-15K15006, KAKENHI-PROJECT-15K15195, KAKENHI-PROJECT-26860372, KAKENHI-PROJECT-15H04841
[Journal Article] CYLD: a critical regulator of hypoxia-mediated inflammation in tumor.2015
- Author(s)
  Jono H, Shinriki S, Guo J, Li JD, Ando Y
- Journal Title
  
  Inflammation and Cell Signaling
  
  Volume: 1
- DOI
  10.14800/ics.479
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26713006
[Journal Article] Osteopontin-integrin α(v)β(3) axis is crucial for 5-fluorouracil resistance in oral squamous cell carcinoma.2015
- Author(s)
  Nakamura T, Shinriki S, Jono H, Ueda M, Nagata M, Guo J, Hayashi M, Yoshida R, Ota T, Ota K, Kawahara K, Nakagawa Y, Yamashita S, Nakayama H, Hiraki A, Shinohara M, Ando Y.
- Journal Title
  
  FEBS Lett
  
  Volume: 589 Issue: 2 Pages: 231-239
- DOI
  10.1016/j.febslet.2014.12.004
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24591269, KAKENHI-PROJECT-25870541, KAKENHI-PROJECT-26713006, KAKENHI-PROJECT-26861735, KAKENHI-PROJECT-26861736, KAKENHI-PROJECT-25461918
[Journal Article] Intrinsic TGF-β2-triggered SDF-1-CXCR4 signaling axis is crucial for drug resistance and a slow-cycling state in bone marrow-disseminated tumor cells.2015
- Author(s)
  Nakamura T, Shinriki S, Jono H, Guo J, Ueda M, Hayashi M, Yamashita S, Zijlstra A, Nakayama H, Hiraki A, Shinohara M, Ando Y.
- Journal Title
  
  Oncotarget
  
  Volume: 6 Pages: 1008-1019
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26713006
[Journal Article] Amyloid deposits derived from transthyretin in the ligamentum flavum as related to lumbar spinal canal stenosis.2015
- Author(s)
  Yanagisawa A, Ueda M, Sueyoshi T, Okada T, Fujimoto T, Ogi Y, Kitagawa K, Tasaki M, Misumi Y, Oshima T, Jono H, Obayashi K, Hirakawa K, Uchida H, Westermark P, Ando Y, Mizuta H.
- Journal Title
  
  Mod Pathol
  
  Volume: 28 Issue: 2 Pages: 201-207
- DOI
  10.1038/modpathol.2014.102
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590699, KAKENHI-PROJECT-25870541, KAKENHI-PROJECT-26860372, KAKENHI-PROJECT-15K15006
[Journal Article] Clinical significance of CYLD downregulation in breast cancer.2014
- Author(s)
  Hayashi M, Jono H, Shinriki S, Nakamura T, Guo J, Sueta A, Tomiguchi M, Fujiwara S, Yamamoto-Ibusuki M, Murakami K, Yamashita S, Yamamoto Y, Li JD, Iwase H, Ando Y.
- Journal Title
  
  Breast Cancer Res Treat.
  
  Volume: 143 Issue: 3 Pages: 447-457
- DOI
  10.1007/s10549-013-2824-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790091, KAKENHI-PROJECT-24591269, KAKENHI-PROJECT-26713006
[Journal Article] Meclofenamate elicits a nephropreventing effect in a rat model of ischemic acute kidney injury by suppressing indoxyl sulfate production and restoring renal organic anion transporters.2014
- Author(s)
  Saigo C, Nomura Y, Yamamoto Y, Sagata M, Matsunaga R, Jono H, Nishi K, Saito H.
- Journal Title
  
  Drug Des. Devel. Ther.
  
  Volume: 8 Pages: 1073-1082
- DOI
  10.2147/dddt.s67456
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25293040, KAKENHI-PROJECT-25670080
[Journal Article] Clinical Significance of CYLD Downregulation in Breast Cancer2014
- Author(s)
  Hayashi M, Jono H, Shinriki S, Nakamura T, Guo J, Sueta A, Tomiguchi M, Fujiwara S, Yamamoto-Ibusuki M, Murakami K, Yamashita S, Yamamoto Y, Li J-D, Iwase H, Ando Y.
- Journal Title
  
  Breast Cancer Res. Treat
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790091
[Journal Article] Carbamazepine-imatinib interaction in a child with chronic myeloid leukemia.2014
- Author(s)
  Taguchi K, Kouroki M, Ohmura T, Jono H, Endo F, Saito H.
- Journal Title
  
  Pediatr Int.
  
  Volume: 56
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670080
[Journal Article] False tacrolimus concentrations measured by antibody-conjugated magnetic immunoassay in liver transplant patient: 2 case reports and literature review.2014
- Author(s)
  Taguchi K, Ohmura T, Ohya Y, Horio M, Furukawa K, Jono H, Inomata Y, Saito H.
- Journal Title
  
  Exp. Clin. Transplant.
  
  Volume: 12 Pages: 474-478
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293040
[Journal Article] Hypoxia suppresses cylindromatosis (CYLD) expression to promote inflammation in glioblastoma: possible link to acquired resistance to anti-VEGF therapy.2014
- Author(s)
  Guo J, Shinriki S, Su Y, Nakamura T, Hayashi M, Tsuda Y, Murakami Y, Tasaki M, Hide T, Takezaki T, Kuratsu J, Yamashita S, Ueda M, Li JD, Ando Y, Jono H.
- Journal Title
  
  Oncotarget
  
  Volume: 5 Pages: 6353-6364
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26713006
[Journal Article] シクロデキストリンの特性を活用した難治性アミロイドーシスの分子創薬2014
- Author(s)
  城野博史
- Journal Title
  
  臨床化学
  
  Volume: 43 Pages: 211-216
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24249036
[Journal Article] Hepatic sulfotransferase as a nephropreventing target by suppression of the uremic toxin indoxyl sulfate accumulation in ischemic acute kidney injury.2014
- Author(s)
  Saito H, Yoshimura M, Saigo C, Komori M, Nomura Y, Yamamoto Y, Sagata M, Wakida A, Chuman E, Nishi K, Jono H.
- Journal Title
  
  Toxicol. Sci.
  
  Volume: 141 Issue: 1 Pages: 206-217
- DOI
  10.1093/toxsci/kfu119
- NAID
  120005663611
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25293040, KAKENHI-PROJECT-25670080
[Journal Article] Stromal Expression of Neutrophil Gelatinase-Associated Lipocalin Correlates with Poor Differentiation and Adverse Prognosis in Oral Squamous Cell Carcinoma2014
- Author(s)
  Shinriki S, Jono H , Ueda M, Obayashi K, Nakamura T, Ota K, Ota T, Sueyoshi T, Guo J, Hayashi M, Hiraki A, Nakayama H, Yamashita S, Shinohara M, Ando Y
- Journal Title
  
  Histopathology
  
  Volume: 64 Pages: 356-64
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790091
[Journal Article] Carbamazepine-imatinib interaction in a child with chronic myeloid leukemia.2014
- Author(s)
  Taguchi K, Kouroki M, Ohmura T, Jono H, Endo F, Saito H.
- Journal Title
  
  Pediatr. Int.
  
  Volume: 56 Issue: 4
- DOI
  10.1111/ped.12382
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25293040, KAKENHI-PROJECT-26713006
[Journal Article] Stromal Expression of Neutrophil Gelatinase-Associated Lipocalin Correlates with Poor Differentiation and Adverse Prognosis in Oral Squamous Cell Carcinoma.2014
- Author(s)
  Shinriki S, Jono H, Ueda M, Obayashi K, Nakamura T, Ota K, Ota T, Sueyoshi T, Guo J, Hayashi M, Hiraki A, Nakayama H, Yamashita S, Shinohara M, Ando Y.
- Journal Title
  
  Histopathology
  
  Volume: 64 Pages: 356-364
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790091
[Journal Article] Effect of albumin on transthyretin and amyloidogenic transthyretin Val30Met disposition and tissue deposition in familial amyloidotic polyneuropathy.2013
- Author(s)
  Taguchi K, Jono H, Kugimiya-Taguchi T, Nagao S, Su Y, Yamasaki K, Mizuguchi M, Maruyama T, Ando Y, Otagiri M.
- Journal Title
  
  Life Sci
  
  Volume: 93 Pages: 1017-1022
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24249036
[Journal Article] Effect of age and sex differences on wild-type transthyretin amyloid formation in familial amyloidotic polyneuropathy: A proteomic approach.2013
- Author(s)
  Tasaki M, Ueda M, Obayashi K, Koike H, Kitagawa K, Ogi Y, Jono H, Su Y, Suenaga G, Oshima T, Misumi Y, Yoshida M, Yamashita T, Sobue G, Ando Y.
- Journal Title
  
  Int J Cardiol
  
  Volume: 170 Pages: 69-74
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24249036
[Journal Article] Inhibition of PDE4B suppresses inflammation by increasing expression of the deubiquitinase CYLD2013
- Author(s)
  Komatsu K
- Journal Title
  
  Nature Communications
  
  Volume: 4 Issue: 1 Pages: 1684-1684
- DOI
  10.1038/ncomms2674
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790091, KAKENHI-PROJECT-23890146, KAKENHI-PROJECT-25253012, KAKENHI-PROJECT-25860223
[Journal Article] CYLD downregulation is correlated with tumor development in patients with hepatocellular carcinoma.2013
- Author(s)
  Kinoshita H, Okabe H, Beppu T, Chikamoto A, Hayashi H, Imai K, Mima K, Nakagawa S, Yokoyama N, Ishiko T, Shinriki S, Jono H, Ando Y, Baba H
- Journal Title
  
  Mol Clin Oncol.
  
  Volume: 1 Pages: 309-314
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790091
[Journal Article] Suppression of inflammation via PDE4B-JNK2-dependent upregulation of deubiquitinase CYLD2013
- Author(s)
  Komatsu K, Lee J, Miyata M, Lim JH, Jono H, Koga T, Xu H, Yan C, Kai H, Li JD
- Journal Title
  
  Nature Commun
  
  Volume: 4 Pages: 1684-1684
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790091
[Journal Article] Changes in pathological and biochemical findings of systemic tissue sites in familial amyloid polyneuropathy more than 10 years after liver transplantation2013
- Author(s)
  Oshima T, Kawahara S, Ueda M, Kawakami Y, Tanaka R, Okazaki T, Misumi Y, Obayashi K, Yamashita T, Ohya Y, Ihse E, Shinriki S, Tasaki M, Jono H, Asonuma K, Inomata Y, Westermark P, Ando Y
- Journal Title
  
  J Neurol Neurosurg Psychiatry
  
  Volume: - Issue: 7 Pages: 740-746
- DOI
  10.1136/jnnp-2013-305973
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23500430, KAKENHI-PROJECT-24249036, KAKENHI-PROJECT-24590699, KAKENHI-PROJECT-24790557, KAKENHI-PROJECT-25870541, KAKENHI-PROJECT-26860672
[Journal Article] CYLD down-regulation is correlated with tumor development in patients with hepatocellular carcinoma2013
- Author(s)
  Kinoshita H, Okabe H, Beppu T, Chikamoto A, Hayashi H, Imai K, Mima K, Nakagawa S, Yokoyama N, Ishiko T, Shinriki S, Jono H, Ando Y, Baba H
- Journal Title
  
  Molecular and Clinical Oncology
  
  Pages: 309-314
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790091
[Journal Article] Impact of antibodies against amyloidogenic transthyretin (ATTR) on phenotypes of patients with familial amyloidotic polyneuropathy (FAP) ATTR Valine30Methionine2013
- Author(s)
  Obayashi K, Tasaki M, Jono H, Ueda M, Shinriki S, Misumi Y, Yamashita T, Oshima T, Nakamura T, Ikemizu S, Anan I, Suhr O, Ando Y
- Journal Title
  
  Clin Chim Acta
  
  Volume: 419 Pages: 127-31
- DOI
  10.1016/j.cca.2013.02.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23500430, KAKENHI-PROJECT-23659303, KAKENHI-PROJECT-24249036, KAKENHI-PROJECT-24590699, KAKENHI-PROJECT-24790557, KAKENHI-PROJECT-25870541, KAKENHI-PUBLICLY-23121523
[Journal Article] Novel function of transthyretin in pancreatic alpha cells.2012
- Author(s)
  Su Y. et al.
- Journal Title
  
  FEBS Letters
  
  Volume: 586 Issue: 23 Pages: 4215-4222
- DOI
  10.1016/j.febslet.2012.10.025
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21220010, KAKENHI-PROJECT-23659303, KAKENHI-PROJECT-23791038, KAKENHI-PROJECT-24249036, KAKENHI-PROJECT-24790557, KAKENHI-PUBLICLY-23126521
[Journal Article] Identification of CXCL5/ENA-78 as a factor involved in the interaction between cholangiocarcinoma cells and cancer-associated fibroblasts2012
- Author(s)
  Okabe H, Beppu T, Ueda M, Hayashi H, Ishiko T, Masuda T, Otao R, Horlad H, Mima K, Miyake K, Iwatsuki M, Baba Y, Takamori H, Jono H, Shinriki S, Ando Y, Baba H
- Journal Title
  
  Int J Cancer
  
  Volume: 131 Pages: 2234-41
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790091
[Journal Article] Potential use of lactosylated dendrimer (G3)/α-cyclodextrin conjugates as hepatocyte-specific siRNA carriers for the treatment of familial amyloidotic polyneuropathy.2012
- Author(s)
  Hayashi Y
- Journal Title
  
  Mol Pharm
  
  Volume: 9 Issue: 6 Pages: 1645-1653
- DOI
  10.1021/mp200654g
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659303, KAKENHI-PROJECT-24249036
[Journal Article] Potential use ofglucuronylglucosyl-β-cyclodextrin as anovel therapeutic tool for familialamyloidotic polyneuropathy2012
- Author(s)
  Jono H, Anno T, Motoyama K, Misumi Y,Tasaki M, Oshima T, Mori Y, Mizuguchi M,Ueda M, Shinriki S, Shono M, Obayashi K,Arima H, Ando Y
- Journal Title
  
  Amyloid
  
  Volume: 19 Suppl 1 Pages: 50-52
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659303
[Journal Article] PKCθsynergizes with TLR-dependent TRAF6 signaling pathway to upregulate MUC5AC mucin via CARMA12012
- Author(s)
  Jono H, Lim JH, Xu H, Li JD
- Journal Title
  
  PLoS ONE
  
  Volume: 7 Pages: 31049-31049
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790091
[Journal Article] Systemic delivery of transthyretin siRNA mediated by lactosylated dendrimer/α-cyclodextrin conjugates into hepatocyte for familial amyloidotic polyneuropathy therapy.2012
- Author(s)
  Hayashi Y
- Journal Title
  
  Amyloid
  
  Volume: 19 Suppl 1 Issue: sup1 Pages: 47-49
- DOI
  10.3109/13506129.2012.674581
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659303, KAKENHI-PROJECT-24249036
[Journal Article] Long-term survival after liver transplantation in patients with familial amyloid polyneuropathy2012
- Author(s)
  Yamashita T, Ando Y, Okamoto S, Misumi Y, Hirahara T, Ueda M, Obayashi K, Nakamura M, Jono H, Shono M, Asonuma K, Inomata T, Uchino M
- Journal Title
  
  Neurology
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390270
[Journal Article] Long-term survival after liver transplantation in patients with familial amyloid polyneuropathy2012
- Author(s)
  Yamashita T, Ando Y, Okamoto S, Misumi Y, Hirahara T, Ueda M, Obayashi K, Nakamura M, Jono H, Shono M, Asonuma K, Inomata Y, Uchino M
- Journal Title
  
  Neurology
  
  Volume: 78(9) Issue: 9 Pages: 637-43
- DOI
  10.1212/wnl.0b013e318248df18
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23500430, KAKENHI-PROJECT-23659303, KAKENHI-PROJECT-24249036
[Journal Article] Potential use of glucuronylglucosyl-β-cyclodextrin as a novel therapeutic tool for familial amyloidotic polyneuropathy.2012
- Author(s)
  Jono H
- Journal Title
  
  Amyloid
  
  Volume: 19 Suppl 1 Pages: 50-52
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659303
[Journal Article] CYLD Negatively Regulates Transforming Growth Factor-B Signaling via Deubiquitinating Akt2012
- Author(s)
  Lim JH, Jono H, Komatsu K, Dr. Woo CH, Lee J, Miyata M, Matsuno T, Xu X, Huang Y, Zhang W, Park SH, Kim YI, Choi YD, Shen H, Heo KS, Xu H, Bourne P, Koga T, Xu H, Yan C, Wang B, Chen LF, Feng XH, Li JD
- Journal Title
  
  Nature Commun
  
  Volume: 3 Pages: 771-771
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790091
[Journal Article] PDE4B mediates ERK dependent up-regulation of mucin MUC5AC by S. pneumoniae by inhibiting cAMP-PKA dependent MKP-1 pathway2012
- Author(s)
  Lee J, Komatsu K, Lee BC, Lim JH, Jono H, Xu H, Kai H, Zhang ZJ, Yan C, Li JD
- Journal Title
  
  J Biol Chem
  
  Volume: 287 Pages: 22799-811
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790091
[Journal Article] Therapeutic approaches targeting midkine suppress tumor growth and lung metastasis in osteosarcoma.2012
- Author(s)
  Takanao Sueyoshi, Hirofumi Jono, Satoru Shinriki, Kazutoshi Ota, Tomoko Ota, Masayoshi Tasaki, Eri Atsuyama, Toshitake Yakushiji, Mitsuharu Ueda, Konen Obayashi, Hiroshi Mizuta, Yukio Ando
- Journal Title
  
  Cancer Letter
  
  Volume: Volume 316, Issue 1 Issue: 1 Pages: 23-30
- DOI
  10.1016/j.canlet.2011.10.013
- NAID
  120004419579
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22592240, KAKENHI-PROJECT-23790091
[Journal Article] Interaction between amyloid fibril formation and extracellular matrix in the proceedings of VIIIth International Symposium on Familial Amyloidotic Polyneuropathy.2012
- Author(s)
  Misumi Y
- Journal Title
  
  Amyloid
  
  Volume: 19 Suppl 1 Issue: sup1 Pages: 8-10
- DOI
  10.3109/13506129.2012.674987
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659303, KAKENHI-PROJECT-24249036, KAKENHI-PROJECT-24590699
[Journal Article] Potential use of glucuronylglucosyl-β-cyclodextrin as a novel therapeutic tool for familial amyloidotic polyneuropathy.2012
- Author(s)
  Jono H
- Journal Title
  
  Amyloid
  
  Volume: 19 Suppl 1 Pages: 50-52
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24249036
[Journal Article] Relationship between amyloid deposition and intracellular structural changes in familial amyloidotic polyneuropathy2012
- Author(s)
  Misumi Y, Ueda M, Obayashi K, Jono H, Su Y, Yamashita T, Ohshima T, Ando Y, Uchino M
- Journal Title
  
  Hum Pathol
  
  Volume: 43 Pages: 96-104
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390270
[Journal Article] The occurrence of islet amyloid polypeptide amyloidosis in Japanese subjects2012
- Author(s)
  Su Y, Misumi Y, Ueda M, Shono M, Tasaki M, Guo J, Jono H, Obayashi K, Senokuchi T, Yamagata K, Ando Y
- Journal Title
  
  Pancreas
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390270
[Journal Article] Therapeutic approaches targeting midkine suppress tumor growth and lung metastasis in osteosarcoma2012
- Author(s)
  Sueyoshi T, Jono H, Shinriki S, Ota K, Ota T, Tasaki M, Atsuyama E, Yakushiji T, Ueda M, Obayashi K, Mizuta H, Ando Y
- Journal Title
  
  Cancer Lett
  
  Volume: 316 Pages: 23-30
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790091
[Journal Article] PKCθ synergizes with TLR-dependent TRAF6 signaling pathway to upregulate MUC5AC mucin via CARMA12012
- Author(s)
  Jono H, Lim JH, Xu H, Li JD.
- Journal Title
  
  PLoS One
  
  Volume: 7 Issue: 1 Pages: e31049-e31049
- DOI
  10.1371/journal.pone.0031049
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790091
[Journal Article] 家族性アミロイドポリニューロパチーにおける臨床症候に対する肝移植の長期的効果の検討2012
- Author(s)
  山下太郎,奥村幸祐,大嶋俊範,三隅洋平,植田明彦,菅智宏,神力悟,植田光晴,城野博史,大林光念,山下賢,前田寧,安東由喜雄
- Journal Title
  
  末梢神経
  
  Volume: 23 Pages: 256-257
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659303
[Journal Article] The occurrence of islet amyloid polypeptide amyloidosis in Japanese subjects.2012
- Author(s)
  Su Y
- Journal Title
  
  Pancreas
  
  Volume: 41 Issue: 6 Pages: 971-973
- DOI
  10.1097/mpa.0b013e318249926a
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659303, KAKENHI-PROJECT-23791038, KAKENHI-PROJECT-24249036, KAKENHI-PROJECT-24790557
[Journal Article] Long-term survival after liver transplantation in patients with familial amyloid polyneuropathy2012
- Author(s)
  Yamashita T
- Journal Title
  
  Neurology
  
  Volume: 78 Pages: 637-43
- DOI
  10.3892/or.2012.1684
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390270, KAKENHI-PROJECT-22592240, KAKENHI-PROJECT-23790091
[Journal Article] Downregulation of midkine induces cisplatin resistance in human oral squamous cell carcinoma2012
- Author(s)
  Ota T, Jono H, Ota K, Shinriki S, Ueda M, Sueyoshi T, Nakatani K, Fujita S, Obayashi K, Shinohara M, Ando Y
- Journal Title
  
  Oncology Reports
  
  Volume: 27 Pages: 1674-80
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790091
[Journal Article] Antibody therapy for familial amyloidotic polyneuropathy.2012
- Author(s)
  Su Y
- Journal Title
  
  Amyloid
  
  Volume: 19 Suppl 1 Issue: sup1 Pages: 45-46
- DOI
  10.3109/13506129.2012.674075
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659303, KAKENHI-PROJECT-24249036, KAKENHI-PROJECT-24790557
[Journal Article] CYLD Negatively Regulates Transforming Growth Factor-B Signaling via Deubiquitinating Akt.2012
- Author(s)
  Lim JH, Jono H, Komatsu K, Woo CH, Lee J, Miyata M, Matsuno T, Xu X, Huang Y, Zhang W, et al.
- Journal Title
  
  Nature Communications
  
  Volume: 3 Issue: 1 Pages: 771-771
- DOI
  10.1038/ncomms1776
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790091
[Journal Article] Aged vervet monkeys developing transthyretin amyloidosis with thehuman disease-causing Ile122 allele : A valid pathological model of the human disease2012
- Author(s)
  Ueda M, Ageyama N, Nakamura S, Nakamura M, Chambers J, Misumi Y, Mizuguchi M, Shinriki S, Kawahara S, Tasaki T, Jono H, Obayashi K, Sasaki E, Une Y, Ando Y
- Journal Title
  
  Lab Invest
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390270
[Journal Article] Identification of CXCL5/ENA-78 as afactor involved in the interactionbetween cholangiocarcinoma cells andcancer-associated fibroblasts.2012
- Author(s)
  Okabe H, Beppu T, Ueda M, Hayashi H,Ishiko T, Masuda T, Otao R, Horlad H,Mima K, Miyake K, Iwatsuki M, Baba Y,Takamori H, Jono H, Shinriki S, AndoY, Baba H
- Journal Title
  
  Int J Cancer 131
  
  Volume: in press Issue: 10 Pages: 2234-41
- DOI
  10.1002/ijc.27496
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791292, KAKENHI-PROJECT-23790091, KAKENHI-PROJECT-23791549
[Journal Article] Potential Use of Lactosylated Dendrimer(G3)/α-Cyclodextrin Conjugates as Hepatocyte-Specific siRNA Carriers for the Treatment of Familial Amyloidotic Polyneuropathy2012
- Author(s)
  Hayashi Y, Mori Y, Yamashita S, Motoyama K, Higashi T, Jono H, Ando Y, Arima H
- Journal Title
  
  Mol Pharm
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390270
[Journal Article] Aged vervet monkeys developing transthyretin amyloidosis with the human disease-causing Ile 122 allele : A valid pathological model of the human disease2012
- Author(s)
  Ueda M
- Journal Title
  
  Lab Invest
  
  Volume: 92 Issue: 3 Pages: 474-84
- DOI
  10.1038/labinvest.2011.195
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390270, KAKENHI-PROJECT-22240053, KAKENHI-PROJECT-23300155, KAKENHI-PROJECT-23659303, KAKENHI-PROJECT-24249036, KAKENHI-PROJECT-24790557
[Journal Article] Cyclodextrin, a novel therapeutic tool for suppressing amyloidogenic transthyretin misfolding in transthyretin-related amyloidosis2011
- Author(s)
  Jono H
- Journal Title
  
  Biochem J
  
  Volume: 437 Pages: 35-42
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659303
[Journal Article] Amyloid neuropathy in a younger domino liver-transplanted recipient2011
- Author(s)
  Obayashi K, Yamashita T, Tasaki M, Ueda M, Shono M, Jono H, Ohshima T, Ohya Y, Asonuma K, Inomata Y, Ando Y
- Journal Title
  
  Muscle Nerve
  
  Volume: 43 Pages: 449-450
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390270
[Journal Article] Clinicopathologicalfeatures of senile systemic amyloidosis : an ante-and post-mortem study2011
- Author(s)
  Ueda M, Horibata Y, Shono M, Misumi Y, Oshima T, Su Y, Tasaki M, Shinriki S, Kawahara S, Jono H, Obayashi K, Ogawa H, Ando Y
- Journal Title
  
  Mod Pathol
  
  Volume: 24 Pages: 1533-1544
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390270
[Journal Article] Amyloid neuropathy in a younger domino liver transplanted recipient.2011
- Author(s)
  Obayashi K, Yamashita T, Tasaki M, Ueda M, Shono M, Jono H, Ohshima T, Ohya Y, Asonuma K, Inomata Y, Ando Y.
- Journal Title
  
  Muscle Nerve 43
  
  Pages: 449-450
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20890167
[Journal Article] Wild-type transthyretin-derived amyloidosis in various ligaments and tendons.2011
- Author(s)
  Sueyoshi T, Ueda M, Jono H, Irie H, Sei A, Ide J, Ando Y, Mizuta H.
- Journal Title
  
  Hum Pathol in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20890167
[Journal Article] In vitro gene delivery mediated by lactosylated dendrimer(generation 3, G3)/α-cyclodextrin conjugates into hepatocytes2011
- Author(s)
  Motoyama K, Mori Y, Yamashita S, Hayashi Y, Jono H, Ando Y, Hirayama F, Uekama K, Arima H
- Journal Title
  
  J Inclu Phenom MacroChem
  
  Volume: 70 Pages: 333-338
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390270
[Journal Article] Cyclodextrin, a novel therapeutic tool for suppressing amyloidogenic transthyretin misfolding in transthyretin-related amyloidosis2011
- Author(s)
  Jono H, Anno T, Motoyama K, Misumi Y, Tasaki T, Oshima T, Mori Y, Mizuguchi M, Ueda M, Shono M, Obayashi K, Arima H, Ando Y
- Journal Title
  
  Biochem J
  
  Volume: 437 Pages: 35-42
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390270
[Journal Article] Manifestations of Transthyretin Related Familial Amyloidotic Polyneuropathy : Long-term Follow-up of Japanese Patients after Liver Transplantation2011
- Author(s)
  Ohya Y, Okamoto S, Tasaki M, Ueda M, Jono H, Obayashi K, Takeda K, Okajima H, Asonuma K, Hara R, Tanihara H, Ando Y, Inomatal Y
- Journal Title
  
  Surg Today
  
  Volume: 41 Pages: 1211-1218
- NAID
  10029524924
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390270
[Journal Article] Effects of a Novel Nonantibiotic Macrolide,EM900, on Cytokine and Mucin Gene Expression in a Human Airway Epithelial Cell Line2011
- Author(s)
  Otsu K, Ishinaga H, Suzuki S, Sugawara A, Sunazuka T, Omura S, Jono H, Takeuchi K
- Journal Title
  
  Pharmacology
  
  Volume: 88 Pages: 327-332
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790091
[Journal Article] Hepatic Stellate Cells Accelerate the Malignant Behavior of Cholangiocarcinoma Cells2011
- Author(s)
  Okabe H, Beppu T, Hayashi H, Ishiko T, Masuda T, Otao R, Horlad H, Jono H, Ueda M, Phd SS, Ando Y, Baba H
- Journal Title
  
  Ann Surg Oncol
  
  Volume: 18 Pages: 1175-1184
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790091
[Journal Article] Effect of cyclodextrins on transthyretin amyloid formation in transthyretin-related amyloidosis2011
- Author(s)
  Jono H
- Journal Title
  
  Amyloid
  
  Volume: 18 (Suppl.1) Issue: sup1 Pages: 58-59
- DOI
  10.3109/13506129.2011.574354020
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659303
[Journal Article] Loss of functional albumin triggers acceleration of transthyretin amyloid fibril formation in familial amyloidotic polyneuropathy.2011
- Author(s)
  Kugimiya T, Jono H, Saito S, Maruyama M, Kadowaki D, Misumi Y, Hoshii Y, Tasaki T, Su Y, Ueda M, Obayashi K, Shono M, Otagiri M, Ando Y.
- Journal Title
  
  Lab Invest in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20890167
[Journal Article] Loss of functional albumin triggersacceleration of transthyretin amyloidfibril formation in familial amyloidotic polyneuropathy2011
- Author(s)
  Kugimiya T, Jono H, Saito S, Maruyama T, Kadowaki D, Misumi T, HoshiiY, Tasaki M, Su Y, Ueda M, Obayashi K, Shono M, Otagiri M, Ando Y
- Journal Title
  
  Lab Invest
  
  Volume: 91 Pages: 1219-1228
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390270
[Journal Article] Hepatic Stellate Cells Accelerate the Malignant Behavior of Cholangiocarcinoma Cells.2011
- Author(s)
  Okabe H, Beppu T, Hayashi H, Ishiko T, Masuda T, Otao R, Horlad H, Jono H, Ueda M, Phd SS, Ando Y, Baba H.
- Journal Title
  
  Ann Surg Oncol 18
  
  Pages: 1175-1184
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20890167
[Journal Article] Effects of a novel nonantibiotic macrolide, EM900, on cytokine and mucin gene expression in a human airway epithelial cell line.2011
- Author(s)
  Otsu K, Ishinaga H, Suzuki S, Sugawara A, Sunazuka T, Omura S, Jono H, Takeuchi K.
- Journal Title
  
  Pharmacology
  
  Volume: 88 Issue: 5-6 Pages: 327-32
- DOI
  10.1159/000334339
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591899, KAKENHI-PROJECT-22890175, KAKENHI-PROJECT-23790091
[Journal Article] Wild-type transthyretin-derived amyloidosis in various ligaments and tendons2011
- Author(s)
  Sueyoshi T, Ueda M, Jono H, Irie H, Sei A, Ide J, Ando Y, Mizuta H
- Journal Title
  
  Human Pathol
  
  Volume: 42 Pages: 1259-1264
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390270
[Journal Article] Manifestations of Transthyretin-Related Familial Amyloidotic Polyneuropathy : Long-term Follow-up of Japanese Patients after Liver Transplantation.2011
- Author(s)
  Ohya Y, Okamoto S, Tasaki M, Ueda M, Jono H, Obayashi K, Takeda K, Okajima H, Asonuma K, Hara R, Tanihara H, Ando Y, Inomata Y.
- Journal Title
  
  Surg Today
  
  Volume: (in press)
- NAID
  10029524924
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390270
[Journal Article] Spinal multifocal amyloidosis derived from wild-type transthyretin2011
- Author(s)
  Sueyoshi T, Ueda M, Sei A, Misumi Y, Oshima T, Yamashita T, Obayashi K, Shinriki S, Jono H, Shono M, Ando Y, Mizuta H
- Journal Title
  
  Amyloid
  
  Volume: 18 Pages: 165-168
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390270
[Journal Article] Cyclodextrin, a novel therapeutic tool for suppressing amyloidogenic transthyretin misfolding in transthyretin-related amyloidosis.2011
- Author(s)
  Jono H, Anno T, Motoyama K, Misumi Y, Tasaki T, Oshima T, Mori Y, Mizuguchi M, Ueda M, Shono M, Obayashi K, Arima H, Ando Y.
- Journal Title
  
  Biochem J in press.
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20890167
[Journal Article] Wild-type transthyretin-derived amyloidosis in various ligaments and tendons.2011
- Author(s)
  Sueyoshi T, Ueda M, Jono H, Irie H, Sei A, Ide J, Ando Y, Mizuta H.
- Journal Title
  
  Hum Pathol.
  
  Volume: (Epub ahead of print)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390270
[Journal Article] Trans Soluble amyloidgenic enhancing factor Circulating via exosomes.2010
- Author(s)
  Tasaki M, Ueda M, Ochiai S, Tanabe Y, Murata S, Su Y, Shinriki S, Jono H, Shono M, Obayashi K, Nakamura T, Yamada M, Ando Y.
- Journal Title
  
  Biochem Biophys Res Commun 400
  
  Pages: 559-562
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20890167
[Journal Article] Amyloid neuropathy in a younger domino liver-transplanted recipient.2010
- Author(s)
  Obayashi K, Yamashita T, Tasaki M, Ueda M, Shono M, Jono H, Ohshima T, Ohya Y, Asonuma K, Inomata Y, Ando Y.
- Journal Title
  
  Muscle Nerve
  
  Volume: 43 Pages: 449-450
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390270
[Journal Article] Effect of recipient-derived cells on the progression of familial amyloidotic polyneuropathy after liver transplantation : a retrospective study2010
- Author(s)
  Ohya Y, Jono H, Nakamura M, Hayashida S, Ueda M, Obayashi K, Misumi S, Asonuma K, Ando Y, Inomata Y
- Journal Title
  
  Ann Clin Biochem
  
  Volume: 47 Pages: 529-534
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390270
[Journal Article] Transmission of circulating cell-free AA amyloid oligomers in exosomes vectors via a prion-like mechanism.2010
- Author(s)
  Tasaki M, Ueda M, Ochiai S, Tanabe Y, Murata S, Misumi Y, Su Y, Sun X, Shinriki S, Jono H, Shono M, Obayashi K, Ando Y.
- Journal Title
  
  Biochem Biopys Res Commun
  
  Volume: 400 Pages: 559-562
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390270
[Journal Article] Transmission of circulating cell-free AA amyloid oligomers in exosomes vectors via a prion-like mechanism2010
- Author(s)
  Tasaki M, Ueda M, Ochiai S, Tanabe Y, Murata S, Misumi Y, Su Y, Sun X, Shinriki S, Jono H, Shono M, Obayashi K, Ando Y
- Journal Title
  
  Biochem Biopys Res Commun
  
  Volume: 400 Pages: 559-562
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390270
[Journal Article] In Vitro and In Vivo Gene Delivery Mediated by Lactosylated Dendrimer/α-Cyclodextrin Conjugates (G2) into Hepatocytes.2010
- Author(s)
  Arima H, Yamashita S, Mori Y, Hayashi Y, Motoyama K, Hattori K, Takeuchi T, Jono H, Ando Y, Hirayama F, Uekama K.
- Journal Title
  
  Journal of Controlled Release 146
  
  Pages: 106-117
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20890167
[Journal Article] In vitro and in vivo gene delivery mediated by Lactosylateddendrimer/alpha-cyclodextrin conjugates(G2) into hepatocytes2010
- Author(s)
  Arima H, Yamashita S, Mori Y, Hayashi Y, Motoyama K, Hattori K, Takeuchi T, Jono H, Ando Y, Hirayama F, Uekama K
- Journal Title
  
  J Control Release
  
  Volume: 146 Pages: 106-117
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390270
[Journal Article] In Vitro and In Vivo Gene Delivery Mediated by Lactosylated endrimer/α-Cyclodextrin Conjugates (G2) into Hepatocytes2010
- Author(s)
  Arima H, Yamashita S, Mori Y, Hayashi Y, Motoyama K, Hattori K, Takeuchi T, Jono H, Ando Y, Hirayama F, Uekama K.
- Journal Title
  
  J Control Release
  
  Volume: 146 Pages: 106-117
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390270
[Journal Article] Ca^2+/calmodulin-stimulate PDE1 regulate the beta-catenin/TCF signaling through PP2A B56 gamma subunit in proliferating vascular smooth muscle cells.2010
- Author(s)
  Jeon KI, Jono H, Miller CL, Cai Y, Lim S, Liu X, Gao P, Abe J, Li JD, Yan C.
- Journal Title
  
  FEBS J 277
  
  Pages: 5026-5039
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20890167
[Journal Article] Vinpocetine inhibits NF-kappaB dependent inflammation via an IKK-dependent but PDE-independent mechanism.2010
- Author(s)
  Jeon KI, Xu X, Aizawa T, Lim JH, Jono H, Kwon DS, Abe J, Berk BC, Li JD, Yan C.
- Journal Title
  
  Proc Natl Acad Sci USA 107
  
  Pages: 9795-9800
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20890167
[Journal Article] Effect of recipient-derived cells on the progression of familial amyloidotic polyneuropathy after liver transplantation : a retrospective study.2010
- Author(s)
  Ohya Y, Jono H, Nakamura M, Hayashida S, Ueda M, Obayashi K, Misumi S, Asonuma K, Ando Y, Inomata Y.
- Journal Title
  
  Ann Clin Biochem
  
  Volume: 47 Pages: 529-534
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390270
[Journal Article] SELDI-TOF mass spectrometry evaluation of variant transthyretins for diagnosis and pathogenesis of familial amyloidotic polyneuropathy2009
- Author(s)
  Ueda M, Misumi Y, Mizuguchi M, Nakamura M, Yamashita T, Sekijima Y, Ota K, Shinriki S, Jono H, Ikeda S, Suhr OB, Ando Y
- Journal Title
  
  Clin Chem
  
  Volume: 55 Pages: 1223-1227
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390270
[Journal Article] β2-ミクログロブリンの分子修飾2009
- Author(s)
  城野博史、安東由喜雄
- Journal Title
  
  腎と骨代謝
  
  Volume: 22 Pages: 13-20
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390270
[Journal Article] Humanized anti-interleukin-6 receptor antibody suppresses tumor angiogenesis and in vivo growth of human oral squamous cell carcinoma.2009
- Author(s)
  Shinriki S, Jono H, Ota K, Ueda M, Kudo M, Ota T, Oike Y, Endo M, Ibusuki M, Hiraki A, Nakayama H, Yoshitake Y, Shinohara M, Ando Y.
- Journal Title
  
  Clin Cancer Res 15
  
  Pages: 5426-5434
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20890167
[Journal Article] Chain reaction of amyloid fibril formation with induction of basement membrane in familial amyloidotic polyneuropathy2009
- Author(s)
  Misumi Y, Ando Y, Ueda M, Obayashi K, Jono H, Su Y, Yamashita T, Uchino M
- Journal Title
  
  J Pathol
  
  Volume: 219 Pages: 481-490
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390270
[Journal Article] SELDI-TOF MS evaluation of variant transthyretins for diagnosis and pathogenesis of familial amyloidotic polyneuropathy.2009
- Author(s)
  Ueda M(Jono H, 9^<th>)
- Journal Title
  
  Clinical Chemistry (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20890167
[Journal Article] SELDI-TOF mass spectrometry evaluation of variant transthyretins for diagnosis and pathogenesis of familial amyloidotic polyneuropathy.2009
- Author(s)
  Ueda M, Misumi Y, Mizuguchi M, Nakamura M, Yamashita T, Sekijima Y, Ota K, Shinriki S, Jono H, Ikeda S, Suhr OB, Ando Y.
- Journal Title
  
  Clin Chem. 55
  
  Pages: 1223-1227
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20890167
[Journal Article] SELDI-TOF Mass Spectrometry Evaluation of Variant Transthyretins for Diagnosis and Pathogenesis of Familial Amyloidotic Polyneuropathy.2009
- Author(s)
  Ueda M, Misumi Y, Mizuguchi M, Nakamura M, Yamashita T, Sekijima Y, Ota K, Shinriki S, Jono H, Ikeda SI, Suhr OB, Ando Y.
- Journal Title
  
  Clin Chem.
  
  Volume: 55 Pages: 1223-1227
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390270
[Journal Article] Glucocorticoids inhibit nontypeable Haemophilus influenzae-induced MUC5AC mucin expression via MARK phosphatase-l-dependent inhibition of p38 MAPK.2009
- Author(s)
  Komatsu K(Jono H, equally contributed)
- Journal Title
  
  Biochemical Journal 417
  
  Pages: 583-591
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20890167
[Journal Article] Synergistic induction of nuclear factor-kappaB by transforming growth factor-beta and tumour necrosis factor-alpha is mediated by protein kinase A-dependent RelA acetylation.2009
- Author(s)
  Ishinaga H, Jono H, Lim JH, Komatsu K, Xu X, Lee J, Woo CH, Xu H, Feng XH, Chen LF, Yan C, Li JD.
- Journal Title
  
  Biochem J. 417
  
  Pages: 583-591
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20890167
[Journal Article] Chain reaction of amyloid fibril formation with induction of basement membrane in familial amyloidotic polyneuropathy.2009
- Author(s)
  Misumi Y, Ando Y, Ueda M, Obayashi K, Jono H, Su Y, Yamashita T, Uchino M.
- Journal Title
  
  J Pathol.
  
  Volume: 219 Pages: 481-490
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390270
[Journal Article] Differential regulation of Streptococcus pneumoniae-induced human MUC5AC mucin expression through distinct MAPK pathways.2009
- Author(s)
  Lim JH, Kim HJ, Komatsu K, Ha U, Huang Y, Jono H, Kweon SM, Lee J, Xu X, Zhang GS, Shen H, Kai H, Zhang W, Xu H, Li JD.
- Journal Title
  
  Am J Transl Res 8
  
  Pages: 300-311
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20890167
[Journal Article] Chain reaction of amyloid fibril formation with induction of basement membrane in familial amyloidotic polyneuropathy.2009
- Author(s)
  Misumi Y, Ando Y, Ueda M, Obayashi K, Jono H, Su Y, Yamashita T, Uchino M.
- Journal Title
  
  J Pathol 219
  
  Pages: 481-490
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20890167
[Journal Article] Midkine as a prognostic biomarker in oral squamous cell carcinoma.2008
- Author(s)
  Ota K, Fujimori H, Ueda M, Shiniriki S, Kudo M, Jono H, Fukuyoshi Y, Yamamoto Y, Sugiuchi H, Iwase H, Shinohara M, Ando Y.
- Journal Title
  
  Br J Cancer 99
  
  Pages: 655-662
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20890167
[Journal Article] Tumor suppressor cylindromatosis acts as a negative regulator for Streptococcus pneumoniae-induced NFAT signaling.2008
- Author(s)
  Koga T(Jono H, 3^<rd>)
- Journal Title
  
  Journal of Biological Chemistry 283
  
  Pages: 12546-12554
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20890167
[Journal Article] Synergistic induction of MUC5AC mucin by nontypeable Haemophilus influenzae and Streptococcus pneumoniae.2008
- Author(s)
  Shen H, Yoshida H, Yan F, Li W, Xu F, Huang H, Jono H, Li JD.
- Journal Title
  
  Biochem Biophys Res Commun 365
  
  Pages: 795-800
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20890167
[Journal Article] Glucocorticoids inhibit nontypeable Haemophilus influenza induced MUC5AC mucin expression via MAPK phosphatase-1 dependent inhibition of p38 MAPK.2008
- Author(s)
  Komatsu K, Jono H, Lim JH, Imasato A, Xu H, Kai H, Yan C, Li JD.
- Journal Title
  
  Biochem Biophys Res Commun. 19
  
  Pages: 763-768
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20890167
[Journal Article] Tumor suppressor cylindromatosis acts as a negative regulator for Streptococcus pneumoniae-induced NFAT signaling.2008
- Author(s)
  Koga T, Lim JH, Jono H, Ha UH, Xu H, Ishinaga H, Morino S, Xu X, Yan C, Kai H, Li JD.
- Journal Title
  
  J Biol Chem 283
  
  Pages: 12546-12554
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20890167
[Patent] 新規なアミロイド線維生成抑制剤2016
- Inventor(s)
  城野博史、有馬英俊、安東由喜雄、本山敬一、東大志
- Industrial Property Rights Holder
  城野博史、有馬英俊、安東由喜雄、本山敬一、東大志
- Industrial Property Rights Type
  特許
- Filing Date
  2016-06-10
- Data Source
  KAKENHI-PROJECT-15K15006
[Patent] 新規なアミロイド線維生成抑制剤2015
- Inventor(s)
  城野博史、有馬英俊、安東由喜雄、本山敬一、東大志
- Industrial Property Rights Holder
  城野博史、有馬英俊、安東由喜雄、本山敬一、東大志
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2015-117150
- Filing Date
  2015-06-10
- Data Source
  KAKENHI-PROJECT-15K15006
[Patent] アミロイド線維形成抑制剤及びその利用2010
- Inventor(s)
  城野博史、安東由喜雄、有馬英俊、植田光晴、本山敬一
- Industrial Property Rights Holder
  熊本大学
- Industrial Property Number
  2009-155158
- Filing Date
  2010-06-30
- Data Source
  KAKENHI-PROJECT-21390270
[Patent] アミロイド線維形成抑制剤及びその利用2009
- Inventor(s)
  城野博史、安東由喜雄、有馬英俊、植田光晴、本山敬一
- Industrial Property Rights Holder
  熊本大学
- Industrial Property Number
  2009-155158
- Filing Date
  2009-06-30
- Data Source
  KAKENHI-PROJECT-21390270
[Presentation] 腫瘍抑制遺伝子CYLD を指標とした新たなEGFR分子標的治療の確立2024
- Author(s)
  米丸興、金丸歩美、神力悟、齋藤秀之、城野博史
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-23K27345
[Presentation] CYLD依存的形質転換を基軸とした難治がんに対する新たな分子標的薬治療の構築2024
- Author(s)
  城野博史、齋藤秀之
- Organizer
  日本薬学会第144年会
- Invited
- Data Source
  KAKENHI-PROJECT-23K27345
[Presentation] Novel drug therapy targeting NF-kB signal for triple-negative breast cancer patients with loss of CYLD expression2023
- Author(s)
  Arakaki H, Kuwano A, Hirai C, Kanemaru A, Hayashi M, Saigou C, Narita Y, Saito H, Jono H
- Organizer
  The 97th Annual Meeting of Japanese Pharmacological Society
- Data Source
  KAKENHI-PROJECT-23K27345
[Presentation] CYLD 発現の消失・悪性化メカニズムに基づく予後不良口腔がん患者への新規薬物療法の開発2023
- Author(s)
  米丸興、末永尚輝、吉田晋太郎、森祥輝、勝目泰槙、松山果穂、新垣ひとみ、安東実咲、大田雅子、齋藤秀之、城野博史
- Organizer
  第33回日本医療薬学会年会
- Data Source
  KAKENHI-PROJECT-23K27345
[Presentation] Novel insights into the development of glioma stem cells in glioblastoma2023
- Author(s)
  Hirofumi Jono
- Organizer
  Executive program of cooperation in the field of science and technology between the government of Italy & Japan
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K27345
[Presentation] 腫瘍抑制遺伝子CYLD 発現低下に着目した悪性腫瘍の新規個別化治療法の探索2023
- Author(s)
  三宅俊介、齋藤秀之、城野博史
- Organizer
  第 7 回日本臨床薬理学会九州・沖縄地方会
- Invited
- Data Source
  KAKENHI-PROJECT-23K27345
[Presentation] CYLD 発現を指標とした標準療法不応口腔癌患者への新規治療戦略の開発2023
- Author(s)
  米丸興、末永尚輝、吉田晋太郎、森祥輝、勝目泰槙、松山果穂、新垣ひとみ、安東実咲、大田雅子、齋藤秀之、城野博史
- Organizer
  第63回日本臨床化学会年次学術集会
- Data Source
  KAKENHI-PROJECT-23K27345
[Presentation] 腫瘍抑制遺伝子 CYLD 発現低下・予後不良の口腔癌患者に対する新規分子標的治療の確立2023
- Author(s)
  米丸興、金丸歩美、末永尚輝、吉田晋太郎、新垣ひとみ、勝目泰槙、松山果穂、安東実咲、太田雅子、三宅俊介、齋藤秀之、城野博史
- Organizer
  第 7 回日本臨床薬理学会九州・沖縄地方会
- Data Source
  KAKENHI-PROJECT-23K27345
[Presentation] 抑肝散が抗認知症薬ドネペジル塩酸塩及び抗精神病薬リスペリドンの体内動態に及ぼす影響2023
- Author(s)
  成瀬遥佳、金子哲也、倉本佳奈、釘本沙和、西村英里、豎道真菜、手束菜月、安東実咲、大井桃、大田雅子、村田司、浜田直優美、兼田桂一郎、古庄史郎、坂元正克、上田啓司、尾田一貴、鬼木健太郎、猿渡淳二、城野博史、古郡規雄
- Organizer
  日本薬学会第１４３年会
- Data Source
  KAKENHI-PROJECT-20K07134
[Presentation] CYLD 依存的形質転換に伴う抗がん剤感受性の変化を軸とした口腔癌に対する新規薬物治療の確立2023
- Author(s)
  米丸興、金丸歩美、末永尚輝、吉田晋太郎、新垣ひとみ、勝目泰槙、松山果穂、安東実咲、大田雅子、三宅俊介、齋藤秀之、城野博史
- Organizer
  第40 回日本薬学会九州山口支部大会
- Data Source
  KAKENHI-PROJECT-23K27345
[Presentation] がんサバイバーに対する漢方処方の情報蓄積にむけた熊本大学病院での漢方薬の使用実態調査2023
- Author(s)
  成瀨遥佳、三宅俊介、鬼木健太郎、猿渡淳二、城野博史
- Organizer
  日本薬学会第１４３年会
- Data Source
  KAKENHI-PROJECT-20K07134
[Presentation] Novel roles of ribosomal protein S6 promotes development and maintenance of glioblastoma multiforme stem cells2022
- Author(s)
  Hirofumi Jono, Yuki Shirakawa, Yuki Ito, Shunsuke Miyake, Ayumi Kanemaru, Takuichiro Hide, Akitake Mukasa, Kunimasa Ohta, Hideyuki Saito
- Organizer
  第95回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-18H02591
[Presentation] 真珠腫組織におけるCYLD 発現に着目した臨床病理学的解析2021
- Author(s)
  三宅俊介、三輪徹、米田剛、金丸歩美、齋藤陽元、蓑田涼生、折田頼尚、齋藤秀之、城野博史
- Organizer
  第61回日本臨床化学会年次学術集会
- Data Source
  KAKENHI-PROJECT-18H02591
[Presentation] CYLD 発現低下による予後不良トリプルネガティブ型乳癌に対するNF-kB シグナル標的治療の有効性2021
- Author(s)
  新垣ひとみ、桑野明香里、平井ちか、末永尚輝、金丸歩美、三宅俊介、林光博、成田勇樹、齋藤秀之、城野博史
- Organizer
  第61回日本臨床化学会年次学術集会
- Data Source
  KAKENHI-PROJECT-18H02591
[Presentation] 進行卵巣癌における腫瘍抑制遺伝子CYLD 発現低下の臨床的意義の解明2021
- Author(s)
  松山果穂、三宅俊介、下村祐美、金丸歩美、西郷智香、成田勇樹、本岡大社、岩越裕、本原剛志、片渕秀隆、齋藤秀之、城野博史
- Organizer
  第61回日本臨床化学会年次学術集会
- Data Source
  KAKENHI-PROJECT-18H02591
[Presentation] リン酸化プロテオミクスを活用したCYLD発現低下・予後不良膠芽腫に対する新規治療標的の探索2021
- Author(s)
  伊藤由貴、山岡道子、白川裕貴、増田豪、秀拓一郎、成田勇樹、齋藤秀之、城野博史
- Organizer
  第74回薬理学会西南部会
- Data Source
  KAKENHI-PROJECT-18H02591
[Presentation] Novel roles of tumor suppressor CYLD in malignant characteristics of glioblastoma multiforme2021
- Author(s)
  Hirofumi Jono, Yuki Ito, Michiko Yamaoka, Yuki Shirakawa, Takuichiro Hide, Hideyuki Saito
- Organizer
  The 23rd Korea-Japan Joint Seminar on Pharmacology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02591
[Presentation] Biological significance of CYLD expression in malignant characteristics of glioblastoma multiforme2021
- Author(s)
  伊藤由貴、山岡道子、白川裕貴、秀拓一郎、齋藤秀之、城野博史
- Organizer
  第94回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-18H02591
[Presentation] 卵巣癌における腫瘍抑制遺伝子CYLD発現消失の臨床薬理学的意義の解明2021
- Author(s)
  三宅俊介、齋藤秀之、城野博史
- Organizer
  第42回日本臨床薬理学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02591
[Presentation] Biological significance of CYLD downregulation in Triple negative breast cancer.2021
- Author(s)
  桑野明香里、平井ちか、末永尚輝、金丸歩美、新垣ひとみ、林光博、西郷智香、齋藤秀之、城野博史
- Organizer
  第94回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-18H02591
[Presentation] 非小細胞肺癌における腫瘍抑制遺伝子CYLD発現の予後・効果予測因子としての可能性の検証2020
- Author(s)
  西村優佳，髙野佳奈子，末永尚輝，三宅俊介，金丸歩美，齋藤秀之，城野博史
- Organizer
  第73回薬理学会西南部会
- Data Source
  KAKENHI-PROJECT-18H02591
[Presentation] UNILATERAL URETER OBSTRUCTION (UUO)-INDUCED RENAL FIBROSIS IS ATTENUATED BY SUPPRESSION OF INDOXYL SULFATE (IS) ACCUMULATION IN SULFOTRANSFERASE (SULT)1A1-DEFICIENT MICE2020
- Author(s)
  Huixian Hou, Nozomi Yabuuchi, Nao Gunda, Rika Fujino, Yuya Hayashi, Yuki Narita, Hirofumi Jono, Hideyuki Saito
- Organizer
  ・The 57th European Renal Association-European Dialysis and Transplant Association (ERA-EDTA) Fully Virtual Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04104
[Presentation] Personalized cancer therapy based on clinical molecular pathogenesis. - Clinical significance of tumor suppressor CYLD in malignant tumors -2020
- Author(s)
  Hirofumi Jono
- Organizer
  Asian Association of Schools of Pharmacy (AASP) Young Scientist Conference 2020
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02591
[Presentation] 口腔腔扁平上皮癌細胞の抗がん剤性感受性に対するがん抑制遺伝子CYLD発現低下の影響2019
- Author(s)
  小関利弥、末永尚輝、金丸歩美、髙野佳奈子、西村優佳、齋藤秀之、城野博史
- Organizer
  第36回日本薬学会九州支部大会
- Data Source
  KAKENHI-PROJECT-18H02591
[Presentation] Sulfotransferase (Sult) 1a1 plays a toxico- pathological role in cisplatin-induced acute kidney injury (AKI) through metabolic generation of indoxyl sulfate (IS)2019
- Author(s)
  Hou K, Fujino R, Unoki S; Tanaka H; Matsushita K, Gunda N, Jono H, Saito H
- Organizer
  World Congress of Nephrology 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04104
[Presentation] 口腔扁平上皮癌におけるがん抑制遺伝子CYLDの治療効果予測マーカーとしての有用性の検証2019
- Author(s)
  小関利弥、末永尚輝、金丸歩美、高野佳奈子、西村優佳、齋藤秀之、城野博史
- Organizer
  医療薬学フォーラム2019 第27回クリニカルファーマシーシンポジウム
- Data Source
  KAKENHI-PROJECT-18H02591
[Presentation] Ischemia-Reperfusion-Induced AKI (IR-AKI) Associated with Renal Fibrosis Is Attenuated Through Suppressing Indoxyl Sulfate Accumulation in Sulfotransferase (Sult) 1a1-Deficient Mice2019
- Author(s)
  Matsushita K, Gunda N, Fujino R, Nishigaki A, Hayashi Y, Nishi K, Jono H, Saito H
- Organizer
  Kidney Week 2019, American Society of Nephrology Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04104
[Presentation] 口腔癌におけるCYLD発現低下誘導性のシスプラチン耐性化機序の解明2019
- Author(s)
  末永尚輝、金丸歩美、小関利弥、齋藤秀之、城野博史
- Organizer
  医療薬学フォーラム2019 第27回クリニカルファーマシーシンポジウム
- Data Source
  KAKENHI-PROJECT-18H02591
[Presentation] Establishing individualized medicine for intractable cancer based on clinical molecular pathogenesis - A novel predictive marker CYLD for molecular targeted therapies -2019
- Author(s)
  Jono H, Saito H
- Organizer
  第92回日本薬理学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02591
[Presentation] 臨床化学的観点を活用した遺伝性 ATTR アミロイドーシスの新規治療戦略の確立2019
- Author(s)
  城野博史、齋藤秀之、安東由喜雄
- Organizer
  日本薬学会第139年会
- Invited
- Data Source
  KAKENHI-PROJECT-17K19498
[Presentation] 口腔癌における腫瘍抑制遺伝子 CYLD 発現の効果予測マーカーとしての有用性2019
- Author(s)
  城野博史、高野佳奈子、西村優佳、末永尚輝、金丸歩美、三宅俊介、小関利弥、齋藤秀之
- Organizer
  日本臨床腫瘍薬学会学術大会2019
- Data Source
  KAKENHI-PROJECT-18H02591
[Presentation] 膠芽腫の薬物治療抵抗性におけるがん抑制遺伝子CYLD発現の意義2019
- Author(s)
  山岡道子、白川裕貴、伊藤由貴、秀拓一郎、齋藤秀之、城野博史
- Organizer
  医療薬学フォーラム2019 第27回クリニカルファーマシーシンポジウム
- Data Source
  KAKENHI-PROJECT-18H02591
[Presentation] 新規効果予測マーカー CYLD の分子診断を基軸とした新たながん分子標的治療の確立2019
- Author(s)
  城野博史
- Organizer
  第59回日本臨床化学会年次学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02591
[Presentation] 糖尿病（DM）併発虚血性急性腎障害（AKI）ラットの病態進展におけるインドキシル硫酸（IS）の関与2019
- Author(s)
  鵜木隼平、小山直子、下河優奈、城野博史、齋藤秀之
- Organizer
  第62回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-17H04104
[Presentation] 血液透析患者における心血管合併症および予後予測因子としてのインドキシル硫酸の有用性検証2019
- Author(s)
  松下馨介、米田剛、中田悦史、西一彦、城野博史、齋藤秀之
- Organizer
  第62回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-17H04104
[Presentation] Loss of tumor suppressor CYLD expression induces cisplatin resistance in oral squamous cell carcinoma2019
- Author(s)
  Suenaga N, Kanemaru A, Ozeki K, Saito H, Jono H
- Organizer
  第29回日本医療薬学会年会（International symposium）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02591
[Presentation] Clinical significance of CYLD down-regulation in invasiveness of triple negative breast cancer2019
- Author(s)
  Kuwano A, Hirai C, Suenaga N, Kanemaru A, Hayashi M, Saito H, Jono H
- Organizer
  第29回日本医療薬学会年会（International symposium）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02591
[Presentation] 卵巣癌における腫瘍抑制遺伝子CYLDの発現消失はAktシグナルを介した悪性化形質獲得の要因となる2019
- Author(s)
  三宅俊介、金丸歩美、高野佳奈子、西郷智香、本岡大社、本原剛志、齋藤秀之、城野博史
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-18H02591
[Presentation] トリプルネガティブ型乳癌の悪性化形質獲得における腫瘍抑制遺伝子CYLD発現低下の臨床的意義2019
- Author(s)
  桑野明香里、平井ちか、末永尚輝、金丸歩美、三宅俊介、林光博、齋藤秀之、城野博史
- Organizer
  第59回日本臨床化学会年次学術集会
- Data Source
  KAKENHI-PROJECT-18H02591
[Presentation] Unilateral Ureter Obstruction (UUO)-Induced Renal Fibrosis Is Attenuated by Suppression of Indoxyl Sulfate (IS) Accumulation in Sulfotransferase (Sult)1a1-Deficient Mice2019
- Author(s)
  Huixian H, Fujino R, Hayashi Y, Unoki J, Matsushita K, Gunda N, Jono H, Saito H
- Organizer
  Kidney Week 2019, American Society of Nephrology Annual Meeting
- Data Source
  KAKENHI-PROJECT-17H04104
[Presentation] 乳癌薬物療法における腫瘍抑制遺伝子 CYLD 発現低下の臨床的意義の解明2018
- Author(s)
  西郷智香、平井ちか、桑野明香里、林光博、岩瀬弘敬、齋藤秀之、城野博史
- Organizer
  第28回日本医療薬学会年会
- Data Source
  KAKENHI-PROJECT-18H02591
[Presentation] Evaluation of Cyclodextrin/Dendrimer Conjugate/shRNA Complex for Treatment of Transthyretin Amyloidosis2018
- Author(s)
  Inoue M, Jono H, Higashi T, Motoyama K, Ando Y, Arima H
- Organizer
  International Symposia on Amyloidosis 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19498
[Presentation] 乳癌薬物療法に対する耐性獲得における生命予後規定因子 CYLD 発現低下の臨床的意義の解明2018
- Author(s)
  城野博史、平井ちか、西郷智香、林光博、神力悟、安東由喜雄、齋藤秀之、岩瀬弘敬
- Organizer
  医療薬学フォーラム2018 第26回クリニカルファーマシーシンポジウム
- Data Source
  KAKENHI-PROJECT-18H02591
[Presentation] 進行卵巣癌における CYLD 発現変動の臨床的意義の解明および分子診断・個別化治療への応用可能性の検討2018
- Author(s)
  三宅俊介、金丸歩美、髙野佳奈子、西郷智香、本岡大社、本原剛志、齋藤秀之、城野博史
- Organizer
  日本臨床化学会第58回年次学術集会
- Data Source
  KAKENHI-PROJECT-18H02591
[Presentation] Loss of CYLD expression correlates with deep tumor invasion & poor prognosis in patients with invasive oral squamous cell carcinoma2018
- Author(s)
  Jono H, Shinriki S, Suenaga N, Kanemaru A, Miyake S, Takano K, Yoshida S, Saito H
- Organizer
  18th World Congress of Basic and Clinical Pharmacology (WCP2018)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02591
[Presentation] 難治性アミロイドーシスに対する薬物治療の現状と今後の展望2018
- Author(s)
  城野博史、安東由喜雄、齋藤秀之
- Organizer
  第28回日本医療薬学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-17K19498
[Presentation] 質量分析を活用したアミロイドーシスの病型診断2018
- Author(s)
  城野博史、田崎雅義、大林光念、安東由喜雄
- Organizer
  第43回日本医用マススペクトル学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-17K19498
[Presentation] 腫瘍悪性化形質における腫瘍抑制遺伝子 CYLD 発現低下の生物学的意義の解明2018
- Author(s)
  髙野佳奈子、西村優佳、末永尚輝、金丸歩美、三宅俊介、小関利弥、齋藤秀之、城野博史
- Organizer
  第35回日本薬学会九州支部大会
- Data Source
  KAKENHI-PROJECT-18H02591
[Presentation] Establishing individualized cancer therapy based on clinical molecular pathogenesis - Clinical significance of tumor suppressor CYLD down-regulation in malignant tumors2018
- Author(s)
  Hirofumi Jono
- Organizer
  第28回日本医療薬学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02591
[Presentation] Therapeutic Approach for Transthyretin Amyloidosis by Targeted Delivery of siRNA Ternary Complex with Cyclodextrin/dendrimer Conjugate2018
- Author(s)
  Hayashi Y, Arima H, Ando Y, Saito H, Jono H
- Organizer
  International Symposia on Amyloidosis 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19498
[Presentation] 乳癌薬物療法における腫瘍抑制遺伝子 CYLD 発現低下の臨床的意義の解明2018
- Author(s)
  城野博史、平井ちか、西郷智香、林光博、神力悟、安東由喜雄、岩瀬弘敬、齋藤秀之
- Organizer
  日本臨床化学会第58回年次学術集会
- Data Source
  KAKENHI-PROJECT-18H02591
[Presentation] Effects of Cyclodextrin/Dendrimer Conjugate/shRNA Complex as a Novel Multi-target Drug on Amyloidoses2018
- Author(s)
  Jono H, Inoue M, Hayashi Y, Ouchi K, Muta K, Higashi T, Motoyama K, Arima H, Ando Y
- Organizer
  International Symposia on Amyloidosis 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19498
[Presentation] 質量分析法が変える難治性アミロイドーシスの治療戦略2017
- Author(s)
  城野博史、田崎雅義、安東由喜雄
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台
- Year and Date
  2017-03-24
- Invited
- Data Source
  KAKENHI-PROJECT-15K15006
[Presentation] Elucidation of mechanism for indoxyl sulfate (IS)-promoted renal fibrotic response in HK-2 cells under hypoxic condition and mice with ischemia-reperfusion (IR)-induced AKI2017
- Author(s)
  Yamashita M, Eto M, Yoneda G, Fujino R, Jono H, Saito H
- Organizer
  ・Kidney Week 2017, American Society of Nephrology Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04104
[Presentation] 臨床病態解析を基盤とした口腔扁平上皮癌の従来にない薬物療法の開発2017
- Author(s)
  城野博史、安東由喜雄、齋藤秀之
- Organizer
  第57回日本臨床化学会年次学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-26713006
[Presentation] 新たながん薬物療法の開発を目指した標的分子探索と臨床応用2017
- Author(s)
  城野博史、齋藤秀之
- Organizer
  医療薬学フォーラム2017 第25回クリニカルファーマシーシンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-26713006
[Presentation] Tumor suppressor CYLD as a novel prognostic biomarker in primary breast cancer2017
- Author(s)
  Jono H, Hayashi M, Shinriki S, Hirai C, Ando Y, Iwase H, Saito H
- Organizer
  ・15th Congress of the International Association of Therapeutic Drug Monitoring & Clinical Toxicology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26713006
[Presentation] 新たながん薬物療法の開発を目指した標的分子探索と臨床応用2017
- Author(s)
  城野博史
- Organizer
  第34回日本薬学会九州支部大会
- Invited
- Data Source
  KAKENHI-PROJECT-26713006
[Presentation] Experimental confirmation of toxico-pharmacological role of sulfate-conjugated uremic solutes in cisplatin nephropathy2017
- Author(s)
  Fujino R, Unoki S, Tanaka H, Matsushita K, Yoneda G, Miyake S, Jono H, Saito H
- Organizer
  ・Kidney Week 2017, American Society of Nephrology Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04104
[Presentation] 低酸素条件下におけるインドキシル硫酸の腎線維化亢進作用メカニズムの解明2017
- Author(s)
  山下真美、衛藤萌、米田剛、藤野梨香、城野博史、齋藤秀之
- Organizer
  第60回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-17H04104
[Presentation] 臨床病態解析に立脚した革新的がん薬物療法の開発2017
- Author(s)
  城野博史、齋藤秀之
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台
- Year and Date
  2017-03-24
- Invited
- Data Source
  KAKENHI-PROJECT-26713006
[Presentation] 分子病理学的解析に基づいたアデニン誘発性慢性腎臓病モデル動物の有用性検証2017
- Author(s)
  飯田優美、阿部絵理佳、藤野梨香、城野博史、齋藤秀之
- Organizer
  第60回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-17H04104
[Presentation] STZ 誘発糖尿病モデルラットにおける虚血性急性腎障害の病態進展因子の探索2016
- Author(s)
  小山直子、下河優奈、桒原孝成、向山政志、城野博史、齋藤秀之
- Organizer
  第59回日本腎臓学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2016-06-17
- Data Source
  KAKENHI-PROJECT-25293040
[Presentation] がんの分子病態解析を基盤とした新たな治療戦略の開発～口腔扁平上皮癌の新たな治療戦略の可能性～2016
- Author(s)
  城野博史
- Organizer
  日本臨床腫瘍薬学会学術大会2016
- Place of Presentation
  鹿児島
- Year and Date
  2016-03-12
- Invited
- Data Source
  KAKENHI-PROJECT-26713006
[Presentation] CKD 病態進展における腫瘍抑制遺伝子CYLD発現消失の臨床的意義2016
- Author(s)
  城野博史、三宅俊介、米田剛、末永尚輝、薮内希実、西一彦、齋藤秀之
- Organizer
  第26回日本医療薬学会年会
- Place of Presentation
  京都
- Year and Date
  2016-09-17
- Data Source
  KAKENHI-PROJECT-25293040
[Presentation] Pathological and molecular characteristics of adenine-induced chronic kidney disease (CKD) model in rats.2016
- Author(s)
  Abe E, Xiao L, Iida Y, Oyama N, Jono H, Saito H
- Organizer
  Kidney Week 2016, American Society of Nephrology Annual Meeting
- Place of Presentation
  Chicago, USA
- Year and Date
  2016-11-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293040
[Presentation] 敗血症性AKIに対するShikoninの腎機能保護効果機構の解明2016
- Author(s)
  川良まどか、松永里香、山本悠子、城野博史、齋藤秀之
- Organizer
  第59回日本腎臓学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2016-06-17
- Data Source
  KAKENHI-PROJECT-25293040
[Presentation] アミロイドーシス根治を目指した革新的マルチターゲット型治療薬の創製2016
- Author(s)
  城野博史
- Organizer
  第4回TR推進合同フォーラム・ライフサイエンス技術交流会
- Place of Presentation
  福岡
- Year and Date
  2016-10-31
- Data Source
  KAKENHI-PROJECT-15K15006
[Presentation] 乳癌における腫瘍抑制遺伝子CYLD発現消失の臨床的意義の解明2016
- Author(s)
  城野博史、林光博、神力悟、安東由喜雄、岩瀬弘敬
- Organizer
  ・医療薬学フォーラム2016／第24回クリニカルファーマシーシンポジウム
- Place of Presentation
  滋賀
- Year and Date
  2016-06-25
- Data Source
  KAKENHI-PROJECT-26713006
[Presentation] 臨床分子病態解析に基づく難治がんの個別化治療の確立2016
- Author(s)
  城野博史
- Organizer
  第33回日本薬学会九州支部大会
- Place of Presentation
  鹿児島
- Year and Date
  2016-12-03
- Invited
- Data Source
  KAKENHI-PROJECT-26713006
[Presentation] Therapeutic effect of polyamidoamine dendrimer on transthyretin-related amyloidosis2016
- Author(s)
  Jono H, Anno T, Hayashi Y, Motoyama K, Ueda M, Obayashi K, Arima H, Ando Y
- Organizer
  XV International Symposium on Amyloidosis
- Place of Presentation
  Uppsala, Sweden
- Year and Date
  2016-07-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15006
[Presentation] 家族性アミロイドポリニューロパチー患者由来iPS細胞を用いた病態解および創薬スクリーニングの有用性2016
- Author(s)
  城野博史、竹下うらん、大内健太、成田泰子、磯野香織、大矢雄希、猪股裕紀洋、安東由喜雄
- Organizer
  第56回日本臨床化学会年次学術集会
- Place of Presentation
  熊本
- Year and Date
  2016-12-02
- Data Source
  KAKENHI-PROJECT-15K15006
[Presentation] 骨髄播種癌細胞の増殖抑制・抗癌剤耐性化における自律的 TGFβ2-SDF1-CXCR4 シグナルの役割2016
- Author(s)
  城野博史、神力悟、松井啓隆、安東由喜雄、齋藤秀之
- Organizer
  日本薬学会第136年会
- Place of Presentation
  横浜
- Year and Date
  2016-03-26
- Data Source
  KAKENHI-PROJECT-26713006
[Presentation] Shikonin Elicits A Nephropreventive Effect In A Murine Model of LPS-Induced Septic AKI by Triggering Nrf2 Activation With Anti-Oxidative Responses.2016
- Author(s)
  Yoneda G, Kawara M, Yamamoto Y, Matsunaga R, Jono H, Saito H
- Organizer
  Kidney Week 2016, American Society of Nephrology Annual Meeting
- Place of Presentation
  Chicago, USA
- Year and Date
  2016-11-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293040
[Presentation] 硫酸転移酵素（SULT）を標的とした従来にない腎保護・治療薬の開発2015
- Author(s)
  山下真実、西郷智香、野村結衣、佐潟雅隆、米田剛、西一彦、城野博史、齋藤秀之
- Organizer
  第55回日本臨床化学会年次学術集会
- Place of Presentation
  大阪
- Year and Date
  2015-10-30
- Data Source
  KAKENHI-PROJECT-25670080
[Presentation] Novel cyclodextrin-based therapeutic approaches for refractory Amyloidosis2015
- Author(s)
  Jono H, Inoue M, Fujisawa K, Hayashi Y, Anno T, Motoyama K, Ando Y, Arima H
- Organizer
  8th Asian Cyclodextrin Conference and 32nd Cyclodextrin Symposium
- Place of Presentation
  Kumamoto
- Year and Date
  2015-05-14
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15006
[Presentation] Clinical significance of CYLD downregulation in glioblastoma:CYLD, a critical regulator of hypoxia-mediated inflammation in tumors2015
- Author(s)
  Jono H, Shinriki S, Guo J, Li JD
- Organizer
  International Symposium on Chronic Inflammatory Diseases
- Place of Presentation
  Kumamoto
- Year and Date
  2015-10-16
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26713006
[Presentation] Involvement of indoxyl sulfate in exacerbated susceptibility of streptozotocin (STZ)-induced2015
- Author(s)
  Shimokawa Y, Oyama N, Kuwabara T, Mukoyama M, Jono H, Saito H
- Organizer
  2015 American Society of Nephrology Annual Meeting
- Place of Presentation
  San Diego, CA, USA
- Year and Date
  2015-11-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25670080
[Presentation] 口腔扁平上皮癌のCisplatin耐性獲得におけるがん抑制遺伝子CYLD発現の意義2015
- Author(s)
  末永尚輝、米田剛、藏満美水、小牟禮奏恵、平井ちか、神力悟、齋藤秀之、城野博史
- Organizer
  第32回日本薬学会九州支部大会
- Place of Presentation
  延岡
- Year and Date
  2015-11-28
- Data Source
  KAKENHI-PROJECT-26713006
[Presentation] CKD 病態進展における慢性炎症制御因子CYLD の病態生理学的意義2015
- Author(s)
  米田剛、末永尚輝、薮内希実、西一彦、城野博史、齋藤秀之
- Organizer
  第58回日本腎臓学会学術総会
- Place of Presentation
  名古屋　名古屋国際会議場
- Year and Date
  2015-06-05
- Data Source
  KAKENHI-PROJECT-25293040
[Presentation] Methotrexate (MTX) induced kidney damage through intracellular mechanism2015
- Author(s)
  Xiao L, Yamakawa Y, Abe E, Yamashita M, Iida Y, Jono H, and Saito H
- Organizer
  International Symposium on Chronic Inflammatory Diseases, Kumamoto (ISCIDK2015)
- Place of Presentation
  熊本　くまもと県民交流館パレア
- Year and Date
  2015-10-16
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293040
[Presentation] Involvement of indoxyl sulfate in exacerbated susceptibility of streptozotocin (STZ)-induced2015
- Author(s)
  Shimokawa Y, Oyama N, Kuwabara T, Mukoyama M, Jono H, Saito H
- Organizer
  2015 American Society of Nephrology Annual Meeting
- Place of Presentation
  Saｎ Diego, USA
- Year and Date
  2015-11-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293040
[Presentation] 急性腎障害に伴う急性肺障害発症メカニズムにおけるインドキシル硫酸の関与2015
- Author(s)
  米田剛、薮内希実、佐潟雅隆、西郷智香、西一彦、城野博史、齋藤秀之
- Organizer
  第55回日本臨床化学会年次学術集会
- Place of Presentation
  大阪
- Year and Date
  2015-10-30
- Data Source
  KAKENHI-PROJECT-25670080
[Presentation] Involvement of CYLD as a regulatory factor in fibrotic response of ischemic AKI kidney and hypoxic HK-2 cells2015
- Author(s)
  Yoneda G, Suenaga N, Yabuuchi N, Nishi K, Jono H, Saito H
- Organizer
  2015 American Society of Nephrology Annual Meeting
- Place of Presentation
  Saｎ Diego, USA
- Year and Date
  2015-11-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293040
[Presentation] Involvement of CYLD as a regulatory factor in fibrotic response of ischemic AKI kidney and hypoxic HK-2 cells2015
- Author(s)
  Yoneda G, Suenaga N, Yabuuchi N, Nishi K, Jono H, Saito H
- Organizer
  2015 American Society of Nephrology Annual Meeting
- Place of Presentation
  San Diego, CA, USA
- Year and Date
  2015-11-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25670080
[Presentation] 硫酸転移酵素（SULT）を標的とした新規腎保護・治療薬の開発2015
- Author(s)
  西郷智香、野村祐衣、米田剛、山本悠子、城野博史、齋藤秀之
- Organizer
  ・医療薬学フォーラム2015／第23回クリニカルファーマシーシンポジウム
- Place of Presentation
  名古屋
- Year and Date
  2015-07-04
- Invited
- Data Source
  KAKENHI-PROJECT-25670080
[Presentation] 硫酸転移酵素（SULT）を標的とした新規腎保護・治療薬の開発2015
- Author(s)
  西郷智香、野村祐衣、米田剛、山本悠子、城野博史、齋藤秀之
- Organizer
  医療薬学フォーラム2015／第23回クリニカルファーマシーシンポジウム
- Place of Presentation
  名古屋　名古屋国際会議場
- Year and Date
  2015-07-04
- Data Source
  KAKENHI-PROJECT-25293040
[Presentation] 乳癌における腫瘍抑制遺伝子 CYLD の臨床的・生物学的意義の解明2015
- Author(s)
  城野博史、林光博、神力悟、齋藤秀之、安東由喜雄、岩瀬弘敬
- Organizer
  第55回日本臨床化学会年次学術集会
- Place of Presentation
  大阪
- Year and Date
  2015-10-30
- Data Source
  KAKENHI-PROJECT-26713006
[Presentation] アミロイドーシス根治を目指した革新的マルチターゲット型治療薬の創製2015
- Author(s)
  城野博史
- Organizer
  第3回TR推進合同フォーラム
- Place of Presentation
  福岡
- Year and Date
  2015-08-31
- Data Source
  KAKENHI-PROJECT-15K15006
[Presentation] Involvement of CYLD as a regulatory factor in fibrotic response of ischemic AKI kidney and hypoxic HK-2 cells2015
- Author(s)
  Yoneda G, Suenaga N, Yabuuchi N, Nishi K, Jono H, Saito H
- Organizer
  2015 American Society of Nephrology Annual Meeting
- Place of Presentation
  San Diego
- Year and Date
  2015-11-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26713006
[Presentation] CKD 病態進展における慢性炎症制御因子CYLD の病態生理学的意義2015
- Author(s)
  米田剛、末永尚輝、薮内希実、西一彦、城野博史、齋藤秀之
- Organizer
  第58回日本腎臓学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2015-06-05
- Data Source
  KAKENHI-PROJECT-25670080
[Presentation] 虚血性急性腎障害ラットにおけるインドキシル硫酸産生阻害の腎保護効果2014
- Author(s)
  小山直子、西郷智香、佐潟雅隆、野村結衣、松永里香、城野博史、西一彦、齋藤秀之
- Organizer
  第67回日本薬理学会西南部会
- Place of Presentation
  福岡
- Year and Date
  2014-11-23
- Data Source
  KAKENHI-PROJECT-25670080
[Presentation] 慢性腎臓病における新規慢性炎症制御因子 CYLD 機能低下の臨床的意義の解明2014
- Author(s)
  米田剛、末永尚輝、薮内希実、西一彦、齋藤秀之、城野博史
- Organizer
  第67回日本薬理学会西南部会
- Place of Presentation
  福岡
- Year and Date
  2014-11-23
- Data Source
  KAKENHI-PROJECT-26713006
[Presentation] 虚血性急性腎障害ラットにおけるインドキシル硫酸産生阻害の腎保護効果2014
- Author(s)
  野村結衣、松永里香、城野博史、西一彦、齋藤秀之
- Organizer
  第67回日本薬理学会西南部会
- Place of Presentation
  福岡
- Year and Date
  2014-11-23
- Data Source
  KAKENHI-PROJECT-25293040
[Presentation] Hepatic sulfotransferase (SULT) as a potential target for amelioration of ischemic acute kidney injury (AKI) by suppressing indoxyl sulfate accumulation2014
- Author(s)
  Saito H, Saigo C, Yoshimura M, Komori M, Yamamoto Y, Nomura Y, Sagata M, Matsunaga R, Nishi K, Jono H
- Organizer
  第8回国際尿毒症学会
- Place of Presentation
  沖縄コンベンションセンター
- Data Source
  KAKENHI-PROJECT-25670080
[Presentation] Involvement of Indoxyl sulfate (IS) in downregulation of pulmonary aquaporin (AQP)-5 in rats caused by bilateral nephrectomy (BNx)-induced acute kidney injury (AKI)2013
- Author(s)
  Sagata M, Saigo C, Yoneda G, Yamamoto Y, Nomura Y, Nishi K, Jono H, Saito H.
- Organizer
  アメリカ腎臓学会第４６回年会
- Place of Presentation
  ジョージア国際会議場（アトランタ）
- Data Source
  KAKENHI-PROJECT-25670080
[Presentation] 虚血再灌流急性腎障害に伴うNrf2活性化にインドキシル硫酸蓄積が関与する2013
- Author(s)
  佐潟雅隆、吉村美里、脇田紋佳、西郷智香、山本悠子、米田剛、中馬江里奈、野村祐衣、松下裕子、西一彦、城野博史、齋藤秀之
- Organizer
  第56回日本腎臓学会学術総会
- Place of Presentation
  東京国際フォーラム
- Data Source
  KAKENHI-PROJECT-25670080
[Presentation] Loss of CYLD promotes cell migration through stabilized ALK5 in human oral squamous cell2013
- Author(s)
  Shinriki S, Jono H, Li J-D, Nakamura T, Hayashi M, Guo J, Shinohara M, Ando Y
- Organizer
  carcinoma AACR Annual meeting
- Place of Presentation
  Washington, USA
- Year and Date
  2013-04-06
- Data Source
  KAKENHI-PROJECT-23790091
[Presentation] Signal transduction mechanisms and their tight regulation in nontypeable Haemophilus influenzae infection2013
- Author(s)
  Hirofumi Jono
- Organizer
  2013 International Meeting of the Microbiological Society of Korea
- Place of Presentation
  Jeonju city, Korea
- Invited
- Data Source
  KAKENHI-PROJECT-23790091
[Presentation] 両腎摘出急性腎障害モデルラットにおいてインドキシル硫酸が肺aquaporin-5の発現減少に関与する2013
- Author(s)
  佐潟雅隆、西郷智香、山本悠子、米田剛、野村祐衣、西一彦、城野博史、齋藤秀之
- Organizer
  第34回日本臨床薬理学会学術総会
- Place of Presentation
  東京国際フォーラム
- Data Source
  KAKENHI-PROJECT-25293040
[Presentation] 虚血再灌流急性腎障害に伴うNrf2活性化にインドキシル硫酸蓄積が関与する2013
- Author(s)
  佐潟雅隆、吉村美里、脇田紋佳、西郷智香、山本悠子、米田剛、中馬江里奈、野村祐衣、松下裕子、西一彦、城野博史、齋藤秀之
- Organizer
  第56回日本腎臓学会学術総会
- Place of Presentation
  東京国際フォーラム
- Data Source
  KAKENHI-PROJECT-25293040
[Presentation] Loss of CYLD promotes cell migration through stabilized ALK5 in human oral squamous cell carcinoma cells.2013
- Author(s)
  Satoru Shinriki, Hirofumi Jono, Jian-Dong Li, Takuya Nakamura, Mitsuhiro Hayashi, Jianying Guo, Masanori Shinohara, Yukio Ando
- Organizer
  AACR Annual Meeting
- Place of Presentation
  Washington, USA
- Data Source
  KAKENHI-PROJECT-23790091
[Presentation] 骨肉腫におけるがん抑制遺伝子CYLDの生物学的活性の解明2013
- Author(s)
  城野博史、末吉貴直、神力悟、厚山恵里、柳澤哲大、薬師寺俊剛、田崎雅義、大林光念、水田博志、安東由喜雄
- Organizer
  日本薬学会第133年会
- Place of Presentation
  パシフィコ横浜、横浜
- Year and Date
  2013-03-27
- Data Source
  KAKENHI-PROJECT-23790091
[Presentation] Uncovering host epithelial signaling networks by respiratory bacterial pathogens2013
- Author(s)
  Jono H
- Organizer
  World-Class University & 5th microbial pathogenesis & immunity symposium
- Place of Presentation
  Su-Won, Korea
- Year and Date
  2013-04-30
- Data Source
  KAKENHI-PROJECT-23790091
[Presentation] Uncovering host epithelial signaling networks by respiratory bacterial pathogens2013
- Author(s)
  Hirofumi Jono
- Organizer
  World-Class University & The 5th microbial pathogenesis & immunity symposium
- Place of Presentation
  Su-Won, Korea
- Invited
- Data Source
  KAKENHI-PROJECT-23790091
[Presentation] Signal transduction mechanisms and their tight regulation in nontypeable Haemophilus influenzae2013
- Author(s)
  Jono H
- Organizer
  infection 2013 International Meeting of the Microbiological Society of Korea
- Place of Presentation
  Jeonju city, Korea
- Year and Date
  2013-05-01
- Data Source
  KAKENHI-PROJECT-23790091
[Presentation] Loss of tumor suppressor CYLD triggers cell invasion of human oral squamous cell carcinoma cells2013
- Author(s)
  城野博史、神力悟、大林光念、安東由喜雄
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡国際会議場、福岡
- Year and Date
  2013-03-21
- Data Source
  KAKENHI-PROJECT-23790091
[Presentation] 骨肉腫におけるがん抑制遺伝子 CYLD の生物学的活性の解明2013
- Author(s)
  城野博史
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜（パシフィコ横浜）
- Data Source
  KAKENHI-PROJECT-23790091
[Presentation] Involvement of Indoxyl sulfate (IS) in downregulation of pulmonary aquaporin (AQP)-5 in rats caused by bilateral nephrectomy (BNx)-induced acute kidney injury (AKI).2013
- Author(s)
  Sagata M, Saigo C, Yoneda G, Yamamoto Y, Nomura Y, Nishi K, Jono H, Saito H.
- Organizer
  アメリカ腎臓学会第４６回年会
- Place of Presentation
  アトランタ
- Data Source
  KAKENHI-PROJECT-25293040
[Presentation] Loss of tumor suppressor CYLD triggers cell invasion of human oral squamous cell carcinoma cells2013
- Author(s)
  城野博史
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡（福岡国際会議場）
- Data Source
  KAKENHI-PROJECT-23790091
[Presentation] 頭頸部扁平上皮癌におけるがん抑制遺伝子CYLD発現低下の臨床的意義の解2012
- Author(s)
  城野博史、神力悟、大林光念、田崎雅義、安東由喜雄
- Organizer
  第65回日本薬理学会西南部会
- Place of Presentation
  熊本,熊本大学薬学部
- Year and Date
  2012-11-23
- Data Source
  KAKENHI-PROJECT-23790091
[Presentation] 骨肉腫進展におけるCYLDの関与と生物学的意義の解明2012
- Author(s)
  城野博史、末吉貴直、神力悟、厚山恵里、柳澤哲大、薬師寺俊剛、田崎雅義、大林光念、水田博志、安東由喜雄
- Organizer
  第52回臨床化学会年会
- Place of Presentation
  いわて県民情報交流センターアイーナ、盛岡
- Year and Date
  2012-09-06
- Data Source
  KAKENHI-PROJECT-23790091
[Presentation] 家族性アミロイドポリニューロパチー患者における異型トランスサイレチンに対する自己抗体の存在とその意義2012
- Author(s)
  大林光念、田崎雅義、神力悟、植田光晴、城野博史、安東由喜雄
- Organizer
  第52回日本臨床化学会年次集会
- Place of Presentation
  いわて県民情報交流センター、盛岡
- Data Source
  KAKENHI-PROJECT-23659303
[Presentation] シクロデキストリンの包接特性を活用した家族性アミロイドポリニューロパチーの新規治療薬の開発2012
- Author(s)
  城野博史、安野貴幸、本山敬一、三隅洋平、田崎雅義、大嶋俊範、森由匡、水口峰之、植田光晴、神力悟、庄野信、大林光念、有馬英俊、安東由喜雄
- Organizer
  日本薬学会第132 年会
- Place of Presentation
  北海道大学、札幌
- Data Source
  KAKENHI-PROJECT-23659303
[Presentation] 頭頸部扁平上皮癌におけるがん抑制遺伝子CYLD発現低下の臨床的意義の解明2012
- Author(s)
  城野博史
- Organizer
  第65回日本薬理学会西南部会
- Place of Presentation
  熊本（熊本大学薬学部）
- Data Source
  KAKENHI-PROJECT-23790091
[Presentation] 骨肉腫進展におけるCYLDの関与と生物学的意義の解明2012
- Author(s)
  城野博史
- Organizer
  第52回日本臨床化学会年次学術集会
- Place of Presentation
  盛岡（いわて県民情報交流センター　アイーナ）
- Data Source
  KAKENHI-PROJECT-23790091
[Presentation] 家族性アミロイドーシスの治療を目指した早期診断, 病態解析法の開発2011
- Author(s)
  城野博史
- Organizer
  第51回臨床化学会年会
- Place of Presentation
  札幌医科大学、札幌
- Data Source
  KAKENHI-PROJECT-23659303
[Presentation] 低酸素環境における腫瘍抑制遺伝子cylincromatosis (CYLD) の発現異常2011
- Author(s)
  郭　建エイ, 神力　悟, 城野　博史, 厚山　恵理, 太田　和俊, 太田　智子, 中村　拓哉, 大林　光念, 安東　由喜雄
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  愛知県名古屋市　名古屋国際会議場
- Data Source
  KAKENHI-PROJECT-23790091
[Presentation] Cylincromatosis（CYLD）発現低下は口腔扁上皮癌の血管新生を誘導する2011
- Author(s)
  村上慶高, 神力悟, 津田幸元, 城野博史, 安東由喜雄
- Organizer
  第51回臨床化学会年会
- Place of Presentation
  北海道札幌市　札幌医科大学
- Data Source
  KAKENHI-PROJECT-23790091
[Presentation] 低酸素環境における腫瘍抑制遺伝子cylincromatosis (CYLD)の発現異常2011
- Author(s)
  津田幸元,神力悟,村上慶高,城野博史,安東由喜雄
- Organizer
  第51回臨床化学会年会
- Place of Presentation
  札幌医科大学、札幌
- Year and Date
  2011-08-28
- Data Source
  KAKENHI-PROJECT-23790091
[Presentation] Cylincromatosis(CYLD)発現低下は口腔扁上皮癌の血管新生を誘導する2011
- Author(s)
  村上慶高,神力悟,津田幸元,城野博史,安東由喜雄
- Organizer
  第51回臨床化学会年会
- Place of Presentation
  札幌医科大学、札幌
- Year and Date
  2011-08-28
- Data Source
  KAKENHI-PROJECT-23790091
[Presentation] Cyclodextrin, a novel therapeutic tool for transthyretin-related amyloidosis2011
- Author(s)
  Jono H
- Organizer
  VIIIth International Symposium on Familial Amyloidotic Polyneuropathy
- Place of Presentation
  The Kumamoto City Medical Association Hall,Kumamoto, Japan
- Data Source
  KAKENHI-PROJECT-23659303
[Presentation] 低酸素環境における腫瘍抑制遺伝子Cylincromatosis（CYLD）の発現異常2011
- Author(s)
  津田幸元,　神力悟, 村上慶高, 城野博史, 安東由喜雄
- Organizer
  第51回臨床化学会年会
- Place of Presentation
  北海道札幌市　札幌医科大学
- Data Source
  KAKENHI-PROJECT-23790091
[Presentation] 低酸素環境における腫瘍抑制遺伝子cylincromatosis (CYLD)の発現異常2011
- Author(s)
  郭建エイ,神力悟,城野博史,厚山恵理,太田和俊,太田智子,中村拓哉,大林光念,安東由喜雄
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場、愛知
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-23790091
[Presentation] シクロデキストリンの包接特性を活用したTTR型アミロイドーシスのアミロイド線維形成抑制メカニズムの解析2011
- Author(s)
  城野博史
- Organizer
  第51回臨床化学会年会
- Place of Presentation
  札幌医科大学、札幌
- Data Source
  KAKENHI-PROJECT-23659303
[Presentation] ヒト化抗IL-6受容体抗体を用いたグリオーマに対する抗腫瘍効果の検討2010
- Author(s)
  城野博史、竹崎達也、神力悟、工藤真励奈、矢野茂敏、中村英夫、牧野敬史、秀拓一郎、牟田大助、植田光晴、倉津純一、安東由喜雄
- Organizer
  第50回臨床化学会年会
- Place of Presentation
  山梨県立県民文化ホール、山梨
- Year and Date
  2010-09-23
- Data Source
  KAKENHI-PROJECT-20890167
[Presentation] Effect of cyclodextrins on transthyretin amyloid formation.2010
- Author(s)
  Jono H, Anno T, Misumi Y, Mori Y, Motoyama K, Ueda M,, Horibata Y, Shono M, Obayashi K, Arima H, Ando Y.
- Organizer
  XII International symposium on amyloidosis
- Place of Presentation
  Crown Plaza Rome, Rome, Italy.
- Data Source
  KAKENHI-PROJECT-20890167
[Presentation] シクロデキストリンを用いたFAPのアミロイド線維形成抑制効果2009
- Author(s)
  安東由喜雄、城野博史、安野貴幸、三隅洋平、大林光念、植田光晴、堀端洋子、有馬英俊
- Organizer
  第50回日本神経学会総会
- Place of Presentation
  仙台・仙台国際センター
- Year and Date
  2009-05-20
- Data Source
  KAKENHI-PROJECT-21390270
[Presentation] シクロデキストリン誘導体を用いたTTR型アミロイドーシスのアミロイド線維形成抑制メカニズムの解析2009
- Author(s)
  城野博史、安野貴幸、三隅洋平、本山敬一、植田光晴、大林光念、堀端洋子、有馬英俊、安東由喜雄
- Organizer
  第56回日本臨床検査医学会学術集会
- Place of Presentation
  札幌コンベンションセンター、札幌
- Year and Date
  2009-08-28
- Data Source
  KAKENHI-PROJECT-20890167
[Presentation] グリオーマの病態解析およびヒト化抗IL-6受容体抗体の抗腫瘍効果の検討2009
- Author(s)
  城野博史、工藤真励奈、神力悟、矢野茂敏、中村英夫、牧野敬史、秀拓一郎、牟田大助、植田光晴、安東由喜雄、倉津純一
- Organizer
  第49回日本臨床化学会年会
- Place of Presentation
  長崎大学医学部、長崎
- Year and Date
  2009-09-19
- Data Source
  KAKENHI-PROJECT-20890167
[Presentation] シクロデキストリン誘導体を用いた家族性アミロイドポリニューロパチー(FAP)の新規治療法の開発2009
- Author(s)
  城野博史、安野貴幸、三隅洋平、大林光念、植田光晴、堀端洋子、有馬英俊、安東由喜雄
- Organizer
  第27回日本神経治療学会総会
- Place of Presentation
  熊本市民会館、熊本
- Year and Date
  2009-06-11
- Data Source
  KAKENHI-PROJECT-20890167
[Presentation] Effect of Albumin on Transthyretin Amyloid Formation.2008
- Author(s)
  Jono H, Saito S, Kugimiya T, Maruyama T, Misumi Y, Hoshii Y, Horibata Y, Ueda M, Otagiri M, Ando Y.
- Organizer
  VIIth International Symposium on Familial Amyloid Polyneuropathy
- Place of Presentation
  King's college London, London, UK.
- Year and Date
  2008-09-03
- Data Source
  KAKENHI-PROJECT-20890167
[Presentation] 分岐β-シクロデキストリンを用いたトランスサイレチンのアミロイド線維形成機構の解析2008
- Author(s)
  城野博史、安野貴幸、本山敬一、三隅洋平、堀端洋子、植田光晴、有馬英俊、安東由喜雄
- Organizer
  第55回日本臨床検査医学会総会
- Place of Presentation
  名古屋国際会議場、名古屋
- Year and Date
  2008-11-30
- Data Source
  KAKENHI-PROJECT-20890167
[Presentation] Clinical significance of CYLD down-regulation in glioblastoma
- Author(s)
  Hirofumi Jono, Jianying Guo, Satoru Shinriki, Konen Obayashi, Yukio Ando
- Organizer
  第８８回日本薬理学会年会
- Place of Presentation
  名古屋
- Year and Date
  2015-03-18 – 2015-03-20
- Data Source
  KAKENHI-PROJECT-26713006
[Presentation] 腫瘍組織における癌抑制遺伝子CYLD発現消失の臨床的意義の解明
- Author(s)
  城野博史、神力悟、植田光晴、大林光念、齋藤秀之、安東由喜雄
- Organizer
  第8回次世代を担う若手医療薬科学シンポジウム
- Place of Presentation
  熊本
- Year and Date
  2014-11-15 – 2014-11-16
- Invited
- Data Source
  KAKENHI-PROJECT-26713006
[Presentation] 硫酸転移酵素（SULT）阻害薬によるインドキシル硫酸（IS）蓄積抑制と急性腎障害低減効果の検証
- Author(s)
  野村祐依、西郷智香、佐潟雅隆、松永里香、城野博史、西一彦、齋藤秀之
- Organizer
  第57回日本腎臓学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2014-07-03 – 2014-07-05
- Data Source
  KAKENHI-PROJECT-25293040
[Presentation] 頭頸部扁平上皮癌におけるがん抑制遺伝子CYLD発現消失の臨床的意義の解明
- Author(s)
  城野博史，神力悟，植田光晴，大林光念，齋藤秀之，安東由喜雄
- Organizer
  第54回日本臨床化学会年次学術集会
- Place of Presentation
  東京
- Year and Date
  2014-09-04 – 2014-09-07
- Data Source
  KAKENHI-PROJECT-26713006
[Presentation] 硫酸転移酵素（SULT）阻害薬によるインドキシル硫酸（IS）蓄積抑制と急性腎障害低減効果の検証
- Author(s)
  野村祐依、西郷智香、佐潟雅隆、松永里香、城野博史、西一彦、齋藤秀之
- Organizer
  第57回日本腎臓学会学術総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-07-03 – 2014-07-05
- Data Source
  KAKENHI-PROJECT-25670080
[Presentation] 乳癌における予後規定因子 CYLD の臨床的・生物学的意義の解明
- Author(s)
  城野博史，林光博, 神力悟，安東由喜雄, 岩瀬弘敬
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-26713006
[Presentation] Meclofenamate elicits a nephropreventing effect in a rat model of ischemic acute kidney injury (AKI) by suppressing indoxyl sulfate (IS) production and restoring renal organic anion transporters
- Author(s)
  Yoneda G, Nomura Y, Saigo C, Yamamoto Y, Jono H, Saito H
- Organizer
  ・2014 American Society of Nephrology Annual Meeting
- Place of Presentation
  Philadelphia、USA
- Year and Date
  2014-11-11 – 2014-11-16
- Data Source
  KAKENHI-PROJECT-25293040
[Presentation] 腎線維化に対する新規慢性炎症制御因子CYLD機能低下の臨床的意義の解明
- Author(s)
  米田剛、末永尚輝、薮内希、西一彦、齋藤秀之、城野博史
- Organizer
  第31回日本薬学会九州支部大会
- Place of Presentation
  福岡
- Year and Date
  2014-12-06 – 2014-12-07
- Data Source
  KAKENHI-PROJECT-25670080
[Presentation] 虚血再灌流急性腎障害ラットにおけるメクロフェナム酸の腎保護効果
- Author(s)
  西郷智香、野村結衣、米田剛、山本悠子、城野博史、齋藤秀之
- Organizer
  第8回次世代を担う若手医療薬科学シンポジウム
- Place of Presentation
  熊本
- Year and Date
  2014-11-15 – 2014-11-16
- Data Source
  KAKENHI-PROJECT-25293040
[Presentation] 腎線維化に対する新規慢性炎症制御因子CYLD機能低下の臨床的意義の解明
- Author(s)
  米田剛、末永尚輝、薮内希、西一彦、齋藤秀之、城野博史
- Organizer
  第31回日本薬学会九州支部大会
- Place of Presentation
  福岡
- Year and Date
  2014-12-06 – 2014-12-07
- Data Source
  KAKENHI-PROJECT-26713006
[Presentation] Meclofenamate elicits a nephropreventing effect in a rat model of ischemic acute kidney injury (AKI) by suppressing indoxyl sulfate (IS) production and restoring renal organic anion transporters
- Author(s)
  Yoneda G, Nomura Y, Saigo C, Yamamoto Y, Jono H, Saito H
- Organizer
  ・2014 American Society of Nephrology Annual Meeting
- Place of Presentation
  Philadelphia, USA
- Year and Date
  2014-11-11 – 2014-11-16
- Data Source
  KAKENHI-PROJECT-25670080
[]

1. ANDO Yukio (20253742)

# of Collaborated Projects: 5 results

# of Collaborated Products: 61 results
2. Saito Hideyuki (40225727)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
3. SHIRAKI Nobuaki (70448520)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. Hidetoshi Arima (50260964)

# of Collaborated Projects: 3 results

# of Collaborated Products: 6 results
5. UEDA Mitsuharu (60452885)

# of Collaborated Projects: 2 results

# of Collaborated Products: 34 results
6. OBAYASHI Konen (90361899)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
7. 大槻純男 (60323036)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. 松井啓隆 (60379849)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
9. KUME Shoen (70347011)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. YAMASHITA Taro (90381003)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
11. YAMASHITA Satoshi (20457592)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
12. TASAKI Masayoshi (50613402)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
13. Saruwatari Junji (30543409)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
14. Kota Kodama (90419424)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 神力悟 (00583048)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
16. 西一彦 (30264287)

# of Collaborated Projects: 1 results

# of Collaborated Products: 13 results
17. 林光博 (50735628)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
18. 北岸宏亮 (60448090)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 古郡規雄 (20333734)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
20. 鬼木健太郎 (00613407)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
21. 仙石愼太郎 (00401224)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 伊藤陽一 (10334236)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 本山敬一 (50515608)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 刈谷龍昇 (40757663)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. SAIGO Chika

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
26. SAGATA Masataka

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
27. Butler James

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. OTA Kazutoshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
29. HIDE Takuichiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
30. ISHINAGA Hajime

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
31. TAKEUCHI Kazuhiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
32. MIMA Kosuke

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
33. MASUDA Toshiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
34. 斎藤秀之

# of Collaborated Projects: 0 results

# of Collaborated Products: 85 results
35. 三隅洋平

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
36. 平原智雄

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
37. 満屋裕明

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Jono Hirofumi 城野 博史

JONO Hirofumi 城野 博史

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Establishing novel molecular-targeted cancer therapies based on tumor suppressor CYLD dependent tumor transformationPrincipal Investigator

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Establishing novel molecular-targeted cancer therapies based on molecular diagnostics focusing on prognostic factor CYLDPrincipal Investigator

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Potential use of multifunctional polyamidoamine Dendrimer for curative treatments of intractable amyloidosesPrincipal Investigator

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Development of novel multi-target drugs for intractable amyloidosesPrincipal Investigator

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Elucidating clinical significance of CYLD down-regulation for establishing individualized cancer therapyPrincipal Investigator

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Jono Hirofumi 城野博史

JONO Hirofumi 城野博史

[Book] 図解腫瘍薬学2020

[Book] 月刊『腎臓内科・泌尿器科』, シスプラチン腎障害－最近の話題2016