TSUIJI Kenji 築地賢治

Researcher Number	40528155
Affiliation *help	2013 – 2015 : 東北大学, 医学(系)研究科(研究院), 助教 2011 – 2013 : Tohoku University, 医学(系)研究科(研究院), 助手 2013 : 東北大学, 大学院医学系研究科, 助教 2012 : 東北大学, 大学院・医学系研究科, 助手 2009 – 2010 : 東北大学, 大学院・医学系研究科, 助手 – 2009 : 東北大学, 医学系研究科, 助教
Review Section/Research Field	Principal Investigator Obstetrics and gynecology Except Principal Investigator Obstetrics and gynecology
Keywords	Principal Investigator モデルマウス / クルクミン / 移植モデルマウス / 子宮筋腫 / ヒト化モデルマウス / mTOR / 子宮平滑筋肉腫 / アポトーシス / ナノクルクミン / 細胞周期 … More Except Principal Investigator … More

Development of the treatment for the uterine leiomyosarcoma using curcuminPrincipal Investigator
- Principal Investigator
  
  Tsuiji Kenji
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Tohoku University
Uterine leiomyoma and AMPK/mTOR signal transduction pathway- a new therapeutic strategy.
- Principal Investigator
  
  TAKEDA Takashi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Kinki University
  Tohoku University
Development of therapeutic agent for uterine leiomyoma using a novel mouse model of human uterine leiomyoma.Principal Investigator
- Principal Investigator
  
  TSUIJI Kenji
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Tohoku University
Uterine leiomyoma and metabolic syndrome-a new therapeutic strategy
- Principal Investigator
  
  TAKEDA Takashi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Tohoku University

All 2014 2013 2012 2011 2010 Other

All Journal Article Presentation

[Journal Article] The antidiabetic drug metformin inhibits uterine leiomyoma cell proliferation via an AMP-activated protein kinase signaling pathway2013
- Author(s)
  Li B, Takeda T, Tsuiji K, Kondo A, Kitamura M, Wong TF, Yaegashi N. Gynecol Endocrinol
- Volume
  29(1)
- Pages
  87-90
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592430
[Journal Article] Curcumin induces cross-regulation between autophagy and apoptosis in uterine leiomyosarcoma cells2013
- Author(s)
  Li B, Takeda T, Tsuiji K, Wong TF, Tadakawa M, Kondo A, Nagase S, Yaegashi N
- Journal Title
  
  Int J Gynecol Cancer
  
  Volume : 23(5) Pages : 803-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592430
[Journal Article] Curcumin targets the AKT-mTOR pathway for uterine leiomyosarcoma tumor growth suppression2013
- Author(s)
  Wong TF, Takeda T, Li B, Tsuiji K, Kondo A, Tadakawa M, Nagase S, Yaegashi N
- Journal Title
  
  Int J Clin Oncol
  
  Volume : (Epub ahead of print)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592430
[Journal Article] Epigallocatechin-3-gallate potentiates curcumin's ability to suppress uterine leiomyosarcoma cell growth and induce apoptosis2013
- Author(s)
  Kondo A, Takeda T, Li B, Tsuiji K, Kitamura M, Wong TF, Yaegashi N
- Journal Title
  
  Int J Clin Oncol
  
  Volume : 18(3) Pages : 380-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592430
[Journal Article] The antidiabetic drug metformin inhibits uterine leiomyoma cell proliferation via an AMP-activated protein kinase signaling pathway.2013
- Author(s)
  Li B, Takeda T, Tsuiji K, Kondo A, Kitamura M, Wong TF, Yaegashi N.
- Journal Title
  
  Gynecol Endocrinol.
  
  Volume : 29 Pages : 87-90
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592430
[Journal Article] Antiproliferative effect of adiponectin on rat uterine leiomyoma ELT-3 cells.2011
- Author(s)
  Wakabayashi A, Takeda T, Tsuiji K, Li B, Sakata M, Morishige KI, Yaegashi N, Kimura T.
- Journal Title
  
  Gynecol Endocrinol.
  
  Volume : 27 Pages : 33-38
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591945
[Journal Article] Inhibitory effect of curcumin on uterine leiomyoma cell proliferation2011
- Author(s)
  Tsuiji K, Takeda T, Li, B, Wakabayashi A, Kondo A, Kimura T, Yaegashi N
- Journal Title
  
  Gyneacol Endocrinol
  
  Volume : 27(7) Pages : 512-517
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791800
[Journal Article] Inhibitory effect of curcumin on uterine leiomyoma cell proliferation.2011
- Author(s)
  Tsuiji K, Takeda T, Li B, Wakabayashi A, Kondo A, Kimura T, Yaegashi N.
- Journal Title
  
  Gynecol Endocrinol.
  
  Volume : 27 Pages : 512-517
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591945
[Journal Article] Curcumin disrupts uterine leiomyosarcoma cells through AKT-mTOR pathway inhibition.2011
- Author(s)
  Wong TF, Takeda T, Li B, Tsuiji K, Kitamura M, Kondo A, Yaegashi N.
- Journal Title
  
  Gynecol Oncol.
  
  Volume : 122 Pages : 141-148
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592430
[Journal Article] Curcumin disrupts uterine leiomyosarcoma cells through AKT-mTOR pathway inhibition2011
- Author(s)
  Wong TF, Takeda T, Li B, Tsuiji K, Kitamura M, Kondo A, Yaegashi N
- Journal Title
  
  Gynecol Oncol
  
  Volume : 122(1) Pages : 141-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592430
[Journal Article] Aldosterone stimulates the proliferation of uterine leiomyoma2010
- Author(s)
  Isobe A, Takeda T, Wakabayashi A, Tsuiji K, Li B, Sakata M, Yaegashi N, Kimura T.
- Journal Title
  
  Gynecol Endocrinol. (未定, 印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591945
[Journal Article] Establishment of a Novel Xenograft Model for Human Uterine Leiomyoma in Immunodeticient Mice2010
- Author(s)
  Tsuiji K, Takeda T, Li B, Kondo A, Ito M, Yaegashi N.
- Journal Title
  
  Tohoku J Exp Med.
  
  Volume : 222 Pages : 55-61
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591945
[Journal Article] Aldosterone stimulates the proliferation of uterine leiomyoma2010
- Author(s)
  Isobe A, Takeda T, Wakabayashi A, Tsuiji K, Li B, Sakata M, Yaegashi N, Kimura T
- Journal Title
  
  Gynecol Endocrinol. 26(5)
  
  Pages : 372-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591945
[Journal Article] Inhibitory effect of curcumin on uterine leiomyoma cell proliferation.2010
- Author(s)
  Tsuiji K, Takeda T, Li B, Wakabayashi A, Kondo A, Kimura T, Yaegashi N
- Journal Title
  
  Gynecol Endocrinol. Jul 30(Epub ahead of print)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591945
[Journal Article] Antiproliferative effect of adiponectin on rat uterine leiomyoma ELT-3 cells.2010
- Author(s)
  Wakabayashi A, Takeda T, Tsuiji K, Li B, Sakata M, Morishige KI, Yaegashi N, Kimura T.
- Journal Title
  
  Gynecol Endocrinol. May 26(Epub ahead of print)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591945
[Journal Article] Establishment of a Novel Xenograft Model for Human Uterine Leiomyoma in Immunodeficient2010
- Author(s)
  Mice Tsuiji K, Takeda T, Li B, Kondo A, Ito M, Yaegashi N.
- Journal Title
  
  Tohoku J Exp Med. 222(1)
  
  Pages : 55-61
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591945
[Presentation] The antidiabetic drug metformin inhibits angiogenesis in uterine leiomyoma in vitro2014
- Author(s)
  Tadakawa M, Takeda T, Li B, Tsuiji K, Yaegashi N
- Organizer
  日本産科婦人科学会
- Place of Presentation
  東京
- Year and Date
  2014-04-18
- Data Source
  KAKENHI-PROJECT-23592430
[Presentation] The anti-diabetic drug metformin suppresses VEGF secretion through inhibition of the mTOR / HIF-1αpathway in uterine leiomyoma cells2014
- Author(s)
  Tadakawa M, Takeda T, Li B, Tsuiji K, Yaegashi N
- Organizer
  ISGE 2014
- Place of Presentation
  Firenze, Italy
- Year and Date
  2014-03-08
- Data Source
  KAKENHI-PROJECT-23592430
[Presentation] 超免疫不全マウスを用いた新規ヒト子宮筋腫移植モデルマウスの確立2012
- Author(s)
  築地謙治、武田卓、李賓、黄志方、近藤亜希子、八重樫伸生
- Organizer
  日本産科婦人科学会
- Place of Presentation
  神戸
- Year and Date
  2012-04-13
- Data Source
  KAKENHI-PROJECT-23791800
[Presentation] 超免疫不全マウスを用いた新規ヒト子宮筋腫移植モデルマウスの確立2011
- Author(s)
  築地謙治、武田卓、李賓、黄志芳、近藤亜希子、八重樫伸生
- Organizer
  第63回日本産婦人科学会学術講演会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-23791800
[Presentation] 天然物ターメリック・ウコン中の有効物質クルクミンによる子宮筋腫治療薬開発～ヒト子宮筋腫モデルマウスを用いたin vivoでの検討～2011
- Author(s)
  築地謙治、武田卓、李賓、黄志芳、近藤亜希子、八重樫伸生
- Organizer
  日本産科婦人科学会
- Place of Presentation
  大阪
- Year and Date
  2011-08-30
- Data Source
  KAKENHI-PROJECT-23791800
[Presentation] メトホルミンによる子宮筋腫細胞増殖抑制効果解析2011
- Author(s)
  北村真理,李賓,築地謙治,黄志芳,近藤亜希子,武田卓,八重樫伸生
- Organizer
  第84回日本内分泌学会
- Place of Presentation
  神戸
- Year and Date
  2011-04-22
- Data Source
  KAKENHI-PROJECT-23592430
[Presentation] ウコン中のクルクミンによる子宮平滑筋肉腫細胞増殖抑制効果～mTORに対する分子標的療法の可能性2011
- Author(s)
  黄志芳,武田卓,李賓,築地謙治,北村真理,近藤亜希子,八重樫伸生
- Organizer
  第50回日本婦人科腫瘍学会
- Place of Presentation
  札幌
- Year and Date
  2011-07-22
- Data Source
  KAKENHI-PROJECT-23592430
[Presentation] メトホルミンによる子宮筋腫細胞増殖抑制効果～子宮筋腫モデル細胞株・ヒト子宮筋腫モデルマウスを用いた検討2011
- Author(s)
  李賓、武田　卓、築地謙治、黄志芳、北村真理、近藤亜希子、八重樫伸生
- Organizer
  第63回日本産婦人科学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-23592430
[Presentation] The anti-diabetic drug metformin suppresses VEGF secretion through inhibition of the mTOR / HIF-1a pathway in uterine leiomyoma cells
- Author(s)
  Tadakawa M, Takeda T, Li B, Tsuiji K, Yaegashi N
- Organizer
  ISGE
- Place of Presentation
  Firenze, Italy
- Data Source
  KAKENHI-PROJECT-23592430
[Presentation] The anti-diabetic drug metformin inhibits angiogenesis through HIF-1/VEGF pathway in uterine leiomyoma in vitro
- Author(s)
  Tadakawa M, Takeda T, Li B, Tsuiji K, Yaegashi N
- Organizer
  日本産科婦人科学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23592430
[Presentation] 天然物ターメリック・ウコン中の有効物質クルクミンによる子宮筋腫治療薬開発～ヒト子宮筋腫モデルマウスを用いたin vivoでの検討～
- Author(s)
  築地謙治
- Organizer
  第64回日本産科婦人科学会学術講演会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23791800

1. TAKEDA Takashi (20301260)

# of Collaborated Projects : 2results

# of Collaborated Products : 22results
2. LI Bin (20566814)

# of Collaborated Projects : 1results

# of Collaborated Products : 14results
3. 森重健一郎 (90283788)

# of Collaborated Projects : 1results

# of Collaborated Products : 2results
4. 澤田健二郎 (00452392)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
5. 坂田正博 (10260639)

# of Collaborated Projects : 1results

# of Collaborated Products : 4results
6. 馬淵誠士 (00452441)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results

TSUIJI Kenji 築地 賢治

Research Projects

Research Products

Co-Researchers

Development of the treatment for the uterine leiomyosarcoma using curcuminPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Uterine leiomyoma and AMPK/mTOR signal transduction pathway- a new therapeutic strategy.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of therapeutic agent for uterine leiomyoma using a novel mouse model of human uterine leiomyoma.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Uterine leiomyoma and metabolic syndrome-a new therapeutic strategy

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] The antidiabetic drug metformin inhibits uterine leiomyoma cell proliferation via an AMP-activated protein kinase signaling pathway2013

Author(s)

Volume

Pages

Data Source

[Journal Article] Curcumin induces cross-regulation between autophagy and apoptosis in uterine leiomyosarcoma cells2013

Author(s)

Journal Title

Data Source

[Journal Article] Curcumin targets the AKT-mTOR pathway for uterine leiomyosarcoma tumor growth suppression2013

Author(s)

Journal Title

Data Source

[Journal Article] Epigallocatechin-3-gallate potentiates curcumin's ability to suppress uterine leiomyosarcoma cell growth and induce apoptosis2013

Author(s)

Journal Title

Data Source

[Journal Article] The antidiabetic drug metformin inhibits uterine leiomyoma cell proliferation via an AMP-activated protein kinase signaling pathway.2013

Author(s)

Journal Title

Data Source

[Journal Article] Antiproliferative effect of adiponectin on rat uterine leiomyoma ELT-3 cells.2011

Author(s)

Journal Title

Data Source

[Journal Article] Inhibitory effect of curcumin on uterine leiomyoma cell proliferation2011

Author(s)

Journal Title

Data Source

[Journal Article] Inhibitory effect of curcumin on uterine leiomyoma cell proliferation.2011

Author(s)

Journal Title

Data Source

[Journal Article] Curcumin disrupts uterine leiomyosarcoma cells through AKT-mTOR pathway inhibition.2011

Author(s)

Journal Title

Data Source

[Journal Article] Curcumin disrupts uterine leiomyosarcoma cells through AKT-mTOR pathway inhibition2011

Author(s)

Journal Title

Data Source

[Journal Article] Aldosterone stimulates the proliferation of uterine leiomyoma2010

Author(s)

Journal Title

Data Source

[Journal Article] Establishment of a Novel Xenograft Model for Human Uterine Leiomyoma in Immunodeticient Mice2010

Author(s)

Journal Title

Data Source

[Journal Article] Aldosterone stimulates the proliferation of uterine leiomyoma2010

Author(s)

Journal Title

TSUIJI Kenji 築地賢治