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TSUIJI Kenji  築地 謙治

ORCIDConnect your ORCID iD *help
Researcher Number 40528155
Other IDs
Affiliation *help 2016 – 2018 : 東北大学, 医学系研究科, 助教
2013 – 2015 : 東北大学, 医学(系)研究科(研究院), 助教
2013 : 東北大学, 大学院医学系研究科, 助教
2011 – 2012 : 東北大学, 医学(系)研究科(研究院), 助手
2012 : 東北大学, 大学院・医学系研究科, 助手
2009 – 2010 : 東北大学, 大学院・医学系研究科, 助手
Review Section/Research Field
Principal Investigator
Obstetrics and gynecology
Except Principal Investigator
Obstetrics and gynecology
Keywords
Principal Investigator
モデルマウス / クルクミン / 移植モデルマウス / 子宮筋腫 / ヒト化モデルマウス / mTOR / 子宮平滑筋肉腫 / アポトーシス / ナノクルクミン / 細胞周期 … More
Except Principal Investigator
… More メトホルミン / mTOR / AMPK / 子宮筋腫 / メタボリックシンドローム / アディポネクチン / 血管新生 / アルドステロン / アンジオテンシン / ヒト子宮筋腫モデル / ELT-3細胞 / VEGF / PPARγ / 細胞増殖 / シグナル伝達 / mTOR / アンギオテンシン / 分子標的 / スピロノラクトン / 移植モデル / HIF1 / ヌードマウス / クルクミン / 高血圧 Less
  • Research Projects

    (4results)
  • Research Products

    (27results)
  • Co-Researchers

    (6People)
  •  Development of the treatment for the uterine leiomyosarcoma using curcuminPrincipal Investigator

    • Principal Investigator
      Tsuiji Kenji
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Tohoku University
  •  Uterine leiomyoma and AMPK/mTOR signal transduction pathway- a new therapeutic strategy.

    • Principal Investigator
      TAKEDA Takashi
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Kinki University
      Tohoku University
  •  Development of therapeutic agent for uterine leiomyoma using a novel mouse model of human uterine leiomyoma.Principal Investigator

    • Principal Investigator
      TSUIJI Kenji
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Tohoku University
  •  Uterine leiomyoma and metabolic syndrome-a new therapeutic strategy

    • Principal Investigator
      TAKEDA Takashi
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Tohoku University

All 2014 2013 2012 2011 2010 Other

All Journal Article Presentation

  • [Journal Article] The antidiabetic drug metformin inhibits uterine leiomyoma cell proliferation via an AMP-activated protein kinase signaling pathway2013

    • Author(s)
      Li B, Takeda T, Tsuiji K, Kondo A, Kitamura M, Wong TF, Yaegashi N. Gynecol Endocrinol
    • Volume
      29(1)
    • Pages
      87-90
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592430
  • [Journal Article] Curcumin induces cross-regulation between autophagy and apoptosis in uterine leiomyosarcoma cells2013

    • Author(s)
      Li B, Takeda T, Tsuiji K, Wong TF, Tadakawa M, Kondo A, Nagase S, Yaegashi N
    • Journal Title

      Int J Gynecol Cancer

      Volume : 23(5) Pages : 803-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592430
  • [Journal Article] Curcumin targets the AKT-mTOR pathway for uterine leiomyosarcoma tumor growth suppression2013

    • Author(s)
      Wong TF, Takeda T, Li B, Tsuiji K, Kondo A, Tadakawa M, Nagase S, Yaegashi N
    • Journal Title

      Int J Clin Oncol

      Volume : (Epub ahead of print)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592430
  • [Journal Article] Epigallocatechin-3-gallate potentiates curcumin's ability to suppress uterine leiomyosarcoma cell growth and induce apoptosis2013

    • Author(s)
      Kondo A, Takeda T, Li B, Tsuiji K, Kitamura M, Wong TF, Yaegashi N
    • Journal Title

      Int J Clin Oncol

      Volume : 18(3) Pages : 380-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592430
  • [Journal Article] The antidiabetic drug metformin inhibits uterine leiomyoma cell proliferation via an AMP-activated protein kinase signaling pathway.2013

    • Author(s)
      Li B, Takeda T, Tsuiji K, Kondo A, Kitamura M, Wong TF, Yaegashi N.
    • Journal Title

      Gynecol Endocrinol.

      Volume : 29 Pages : 87-90

    • DOI
      10.3109/09513590.2012.706668
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592430
  • [Journal Article] Antiproliferative effect of adiponectin on rat uterine leiomyoma ELT-3 cells.2011

    • Author(s)
      Wakabayashi A, Takeda T, Tsuiji K, Li B, Sakata M, Morishige KI, Yaegashi N, Kimura T.
    • Journal Title

      Gynecol Endocrinol.

      Volume : 27 Pages : 33-38

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591945
  • [Journal Article] Inhibitory effect of curcumin on uterine leiomyoma cell proliferation2011

    • Author(s)
      Tsuiji K, Takeda T, Li, B, Wakabayashi A, Kondo A, Kimura T, Yaegashi N
    • Journal Title

      Gyneacol Endocrinol

      Volume : 27(7) Pages : 512-517

    • DOI
      10.3109/09513590.2010.507287
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23791800
  • [Journal Article] Inhibitory effect of curcumin on uterine leiomyoma cell proliferation.2011

    • Author(s)
      Tsuiji K, Takeda T, Li B, Wakabayashi A, Kondo A, Kimura T, Yaegashi N.
    • Journal Title

      Gynecol Endocrinol.

      Volume : 27 Pages : 512-517

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591945
  • [Journal Article] Curcumin disrupts uterine leiomyosarcoma cells through AKT-mTOR pathway inhibition.2011

    • Author(s)
      Wong TF, Takeda T, Li B, Tsuiji K, Kitamura M, Kondo A, Yaegashi N.
    • Journal Title

      Gynecol Oncol.

      Volume : 122 Pages : 141-148

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592430
  • [Journal Article] Curcumin disrupts uterine leiomyosarcoma cells through AKT-mTOR pathway inhibition2011

    • Author(s)
      Wong TF, Takeda T, Li B, Tsuiji K, Kitamura M, Kondo A, Yaegashi N
    • Journal Title

      Gynecol Oncol

      Volume : 122(1) Pages : 141-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592430
  • [Journal Article] Aldosterone stimulates the proliferation of uterine leiomyoma2010

    • Author(s)
      Isobe A, Takeda T, Wakabayashi A, Tsuiji K, Li B, Sakata M, Yaegashi N, Kimura T.
    • Journal Title

      Gynecol Endocrinol. (未定, 印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591945
  • [Journal Article] Establishment of a Novel Xenograft Model for Human Uterine Leiomyoma in Immunodeticient Mice2010

    • Author(s)
      Tsuiji K, Takeda T, Li B, Kondo A, Ito M, Yaegashi N.
    • Journal Title

      Tohoku J Exp Med.

      Volume : 222 Pages : 55-61

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591945
  • [Journal Article] Aldosterone stimulates the proliferation of uterine leiomyoma2010

    • Author(s)
      Isobe A, Takeda T, Wakabayashi A, Tsuiji K, Li B, Sakata M, Yaegashi N, Kimura T
    • Journal Title

      Gynecol Endocrinol. 26(5)

      Pages : 372-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591945
  • [Journal Article] Inhibitory effect of curcumin on uterine leiomyoma cell proliferation.2010

    • Author(s)
      Tsuiji K, Takeda T, Li B, Wakabayashi A, Kondo A, Kimura T, Yaegashi N
    • Journal Title

      Gynecol Endocrinol. Jul 30(Epub ahead of print)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591945
  • [Journal Article] Antiproliferative effect of adiponectin on rat uterine leiomyoma ELT-3 cells.2010

    • Author(s)
      Wakabayashi A, Takeda T, Tsuiji K, Li B, Sakata M, Morishige KI, Yaegashi N, Kimura T.
    • Journal Title

      Gynecol Endocrinol. May 26(Epub ahead of print)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591945
  • [Journal Article] Establishment of a Novel Xenograft Model for Human Uterine Leiomyoma in Immunodeficient2010

    • Author(s)
      Mice Tsuiji K, Takeda T, Li B, Kondo A, Ito M, Yaegashi N.
    • Journal Title

      Tohoku J Exp Med. 222(1)

      Pages : 55-61

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591945
  • [Presentation] The antidiabetic drug metformin inhibits angiogenesis in uterine leiomyoma in vitro2014

    • Author(s)
      Tadakawa M, Takeda T, Li B, Tsuiji K, Yaegashi N
    • Organizer
      日本産科婦人科学会
    • Place of Presentation
      東京
    • Year and Date
      2014-04-18
    • Data Source
      KAKENHI-PROJECT-23592430
  • [Presentation] The anti-diabetic drug metformin suppresses VEGF secretion through inhibition of the mTOR / HIF-1αpathway in uterine leiomyoma cells2014

    • Author(s)
      Tadakawa M, Takeda T, Li B, Tsuiji K, Yaegashi N
    • Organizer
      ISGE 2014
    • Place of Presentation
      Firenze, Italy
    • Year and Date
      2014-03-08
    • Data Source
      KAKENHI-PROJECT-23592430
  • [Presentation] 超免疫不全マウスを用いた新規ヒト子宮筋腫移植モデルマウスの確立2012

    • Author(s)
      築地謙治、武田卓、李賓、黄志方、近藤亜希子、八重樫伸生
    • Organizer
      日本産科婦人科学会
    • Place of Presentation
      神戸
    • Year and Date
      2012-04-13
    • Data Source
      KAKENHI-PROJECT-23791800
  • [Presentation] 超免疫不全マウスを用いた新規ヒト子宮筋腫移植モデルマウスの確立2011

    • Author(s)
      築地謙治、武田卓、李賓、黄志芳、近藤亜希子、八重樫伸生
    • Organizer
      第63回日本産婦人科学会学術講演会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-23791800
  • [Presentation] 天然物ターメリック・ウコン中の有効物質クルクミンによる子宮筋腫治療薬開発~ヒト子宮筋腫モデルマウスを用いたin vivoでの検討~2011

    • Author(s)
      築地謙治、武田卓、李賓、黄志芳、近藤亜希子、八重樫伸生
    • Organizer
      日本産科婦人科学会
    • Place of Presentation
      大阪
    • Year and Date
      2011-08-30
    • Data Source
      KAKENHI-PROJECT-23791800
  • [Presentation] メトホルミンによる子宮筋腫細胞増殖抑制効果解析2011

    • Author(s)
      北村真理,李賓,築地謙治,黄志芳,近藤亜希子,武田卓,八重樫伸生
    • Organizer
      第84回日本内分泌学会
    • Place of Presentation
      神戸
    • Year and Date
      2011-04-22
    • Data Source
      KAKENHI-PROJECT-23592430
  • [Presentation] ウコン中のクルクミンによる子宮平滑筋肉腫細胞増殖抑制効果~mTORに対する分子標的療法の可能性2011

    • Author(s)
      黄志芳,武田卓,李賓,築地謙治,北村真理,近藤亜希子,八重樫伸生
    • Organizer
      第50回日本婦人科腫瘍学会
    • Place of Presentation
      札幌
    • Year and Date
      2011-07-22
    • Data Source
      KAKENHI-PROJECT-23592430
  • [Presentation] メトホルミンによる子宮筋腫細胞増殖抑制効果~子宮筋腫モデル細胞株・ヒト子宮筋腫モデルマウスを用いた検討2011

    • Author(s)
      李 賓、武田 卓、築地 謙治、黄 志芳、北村真理、近藤 亜希子、八重樫 伸生
    • Organizer
      第63回日本産婦人科学会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-23592430
  • [Presentation] The anti-diabetic drug metformin suppresses VEGF secretion through inhibition of the mTOR / HIF-1a pathway in uterine leiomyoma cells

    • Author(s)
      Tadakawa M, Takeda T, Li B, Tsuiji K, Yaegashi N
    • Organizer
      ISGE
    • Place of Presentation
      Firenze, Italy
    • Data Source
      KAKENHI-PROJECT-23592430
  • [Presentation] The anti-diabetic drug metformin inhibits angiogenesis through HIF-1/VEGF pathway in uterine leiomyoma in vitro

    • Author(s)
      Tadakawa M, Takeda T, Li B, Tsuiji K, Yaegashi N
    • Organizer
      日本産科婦人科学会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23592430
  • [Presentation] 天然物ターメリック・ウコン中の有効物質クルクミンによる子宮筋腫治療薬開発~ヒト子宮筋腫モデルマウスを用いたin vivoでの検討~

    • Author(s)
      築地謙治
    • Organizer
      第64回日本産科婦人科学会学術講演会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-23791800
  • 1.  TAKEDA Takashi (20301260)
    # of Collaborated Projects : 2results
    # of Collaborated Products : 22results
  • 2.  LI Bin (20566814)
    # of Collaborated Projects : 1results
    # of Collaborated Products : 14results
  • 3.  森重 健一郎 (90283788)
    # of Collaborated Projects : 1results
    # of Collaborated Products : 2results
  • 4.  澤田 健二郎 (00452392)
    # of Collaborated Projects : 1results
    # of Collaborated Products : 0results
  • 5.  坂田 正博 (10260639)
    # of Collaborated Projects : 1results
    # of Collaborated Products : 4results
  • 6.  馬淵 誠士 (00452441)
    # of Collaborated Projects : 1results
    # of Collaborated Products : 0results

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