OIKAWA Hiroyuki 小井川浩之

Researcher Number	40536778
Other IDs	https://orcid.org/0000-0001-5216-0813
Affiliation (based on the past Project Information) *help	2017 – 2021: 東北大学, 多元物質科学研究所, 助教
Review Section/Research Field	Principal Investigator Basic Section 43040:Biophysics-related / Biophysics Except Principal Investigator Science and Engineering
Keywords	Principal Investigator タンパク質 / FRET / 蛍光一分子分光 / 一分子蛍光測定 / LAF1-RGGドメイン / 液-液相分離 / 夾雑環境 / 混雑環境 / 生物物理 / 遷移経路 / フォールディング … More Except Principal Investigator … More 一分子選別装置 / ファージ・ディスプレイ法 / タンパク質のフォールディング / 一分子ソーター / プロテインAのBドメイン / タンパク質 / 一分子計測（SMD） / 蛋白質 / 一分子蛍光分光 / ダイナミクス / タンパク質科学 / 生物物理 / 一分子蛍光観察 / タンパク質フォールディング / p53 / 一分子蛍光分光法 / フォールディング / タンパク質ダイナミクス Less

Tracking of protein conformational fluctuations in droplets of liquid-liquid phase separation by using single-molecule fluorescence spectroscopyPrincipal Investigator
- Principal Investigator
  
  Oikawa Hiroyuki
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43040:Biophysics-related
- Research Institution
  Tohoku University
Tracking of protein conformational changes in crowded environments by using single-molecule fluorescence spectroscopyPrincipal Investigator
- Principal Investigator
  
  小井川浩之
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Research Institution
  Tohoku University
Tracking of protein folding transition path by single-molecule fluorescence measurementsPrincipal Investigator
- Principal Investigator
  
  Oikawa Hiroyuki
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biophysics
- Research Institution
  Tohoku University
Investigation on the dynamics of protein folding by single molecule fluorescence spectroscopy
- Principal Investigator
  
  Takahashi Satoshi
- Project Period (FY)
  2013 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  Tohoku University

All 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 Other

All Journal Article Presentation Book

[Book] 相分離生物学の全貌（現代化学増刊46), 第Ⅵ部, 76節2020
- Author(s)
  高橋聡, 小井川浩之
- Total Pages
  5
- Publisher
  東京化学同人
- ISBN
  9784807913466
- Data Source
  KAKENHI-PROJECT-19K06577
[Book] 「揺らぎ・ダイナミクスと生体機能～物理化学的視点から見た生体分子～」2013
- Author(s)
  小井川浩之・鎌形清人・高橋聡
- Total Pages
  14
- Publisher
  化学同人
- Data Source
  KAKENHI-PLANNED-25104007
[Journal Article] Quantification of Entropic Excluded Volume Effects Driving Crowding-Induced Collapse and Folding of a Disordered Protein2022
- Author(s)
  Rajendran Divya、Mitra Shrutarshi、Oikawa Hiroyuki、Madhurima Kulkarni、Sekhar Ashok、Takahashi Satoshi、Naganathan Athi N.
- Journal Title
  
  The Journal of Physical Chemistry Letters
  
  Volume: 13 Issue: 13 Pages: 3112-3120
- DOI
  10.1021/acs.jpclett.2c00316
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06577, KAKENHI-PROJECT-20K21166, KAKENHI-PROJECT-21H02438
[Journal Article] Molecular principles of recruitment and dynamics of guest proteins in liquid droplets2021
- Author(s)
  Kamagata Kiyoto、Iwaki Nanako、Hazra Milan Kumar、Kanbayashi Saori、Banerjee Trishit、Chiba Rika、Sakomoto Seiji、Gaudon Virginie、Castaing Bertrand、Takahashi Hiroto、Kimura Michiko、Oikawa Hiroyuki、Takahashi Satoshi、Levy Yaakov
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 19323-19323
- DOI
  10.1038/s41598-021-98955-0
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06577, KAKENHI-PROJECT-20K05746, KAKENHI-PROJECT-20K06571, KAKENHI-PROJECT-21H02438, KAKENHI-PUBLICLY-21H00379
[Journal Article] Extracellular mRNA transported to the nucleus exerts translation-independent function2021
- Author(s)
  Tomita Takeshi、Kato Masayoshi、Mishima Taishi、Matsunaga Yuta、Sanjo Hideki、Ito Ken-ichi、Minagawa Kentaro、Matsui Toshimitsu、Oikawa Hiroyuki、Takahashi Satoshi、Takao Toshifumi、Iwai Noriki、Mino Takashi、Takeuchi Osamu、Maru Yoshiro、Hiratsuka Sachie
- Journal Title
  
  Nature Communications
  
  Volume: 12 Issue: 1 Pages: 3655-3655
- DOI
  10.1038/s41467-021-23969-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06577, KAKENHI-PROJECT-18H05278, KAKENHI-PROJECT-19H03488, KAKENHI-PROJECT-19H03500, KAKENHI-PROJECT-20K06554, KAKENHI-PROJECT-21K06868, KAKENHI-PROJECT-19H03506, KAKENHI-PROJECT-21H02438
[Journal Article] Hypothesis: structural heterogeneity of the unfolded proteins originating from the coupling of the local clusters and the long-range distance distribution2018
- Author(s)
  Takahashi Satoshi、Yoshida Aya、Oikawa Hiroyuki
- Journal Title
  
  Biophysical Reviews
  
  Volume: 印刷中 Issue: 2 Pages: 363-373
- DOI
  10.1007/s12551-018-0405-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K17608, KAKENHI-PLANNED-25104007, KAKENHI-PROJECT-18H02382
[Journal Article] Microsecond resolved single-molecule FRET time series measurements based on the line confocal optical system combined with hybrid photodetectors2018
- Author(s)
  Hiroyuki Oikawa、Takumi Takahashi、Supawich Kamonprasertsukac、Satoshi Takahashi
- Journal Title
  
  Physical Chemistry Chemical Physics
  
  Volume: 20 Issue: 5 Pages: 3277-3285
- DOI
  10.1039/c7cp06268k
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K17608, KAKENHI-PLANNED-25104007, KAKENHI-PROJECT-18H02382
[Journal Article] Highly Heterogeneous Nature of the Native and Unfolded States of the B Domain of Protein A Revealed by Two-Dimensional Fluorescence Lifetime Correlation Spectroscopy2017
- Author(s)
  Otosu Takuhiro、Ishii Kunihiko、Oikawa Hiroyuki、Arai Munehito、Takahashi Satoshi、Tahara Tahei
- Journal Title
  
  The Journal of Physical Chemistry B
  
  Volume: 121 Issue: 22 Pages: 5463-5473
- DOI
  10.1021/acs.jpcb.7b00546
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K17608, KAKENHI-PLANNED-25104005, KAKENHI-PLANNED-25104007, KAKENHI-PROJECT-16H02217, KAKENHI-PROJECT-15K07023, KAKENHI-PROJECT-15KT0139
[Journal Article] Significant Heterogeneity and Slow Dynamics of the Unfolded Ubiquitin Detected by the Line Confocal Method of Single-Molecule Fluorescence Spectroscopy2016
- Author(s)
  Masataka Saito, Supawich Kamonprasertsuk, Satomi Suzuki, Kei Nanatani, Hiroyuki Oikawa, Keiichiro Kushiro, Madoka Takai, Po-ting Chen, Eric H.-L. Chen, Rita P.-Y. Chen, Satoshi Takahashi
- Journal Title
  
  J. Phys. Chem. B
  
  Volume: 120 Issue: 34 Pages: 8818-8829
- DOI
  10.1021/acs.jpcb.6b05481
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24241042, KAKENHI-PLANNED-25104007, KAKENHI-PROJECT-15J05654, KAKENHI-PROJECT-26282213
[Journal Article] Complexity of the folding transition of the B domain of protein A revealed by the high-speed tracking of single-molecule fluorescence time series2015
- Author(s)
  Hiroyuki Oikawa, Kiyoto Kamagata, Munehito Arai, Satoshi Takahashi
- Journal Title
  
  J. Phys. Chem. B
  
  Volume: 119 Issue: 20 Pages: 6081-6091
- DOI
  10.1021/acs.jpcb.5b00414
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K07023, KAKENHI-PUBLICLY-15H01311, KAKENHI-PLANNED-25104007, KAKENHI-PROJECT-26650045, KAKENHI-PROJECT-26840045, KAKENHI-PROJECT-26282213, KAKENHI-PUBLICLY-15H01625
[Journal Article] Where the complex things are: single molecule andensemble spectroscopic investigations of protein folding dynamics2015
- Author(s)
  Satoshi Tkahahshi, Kiyoto Kamagata, Hiroyuki Oikawa
- Journal Title
  
  Current Opinion in Structural Biology
  
  Volume: 36 Pages: 1-9
- DOI
  10.1016/j.sbi.2015.11.006
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-25104007, KAKENHI-PROJECT-26650045, KAKENHI-PROJECT-26840045, KAKENHI-PROJECT-26282213, KAKENHI-PUBLICLY-15H01625
[Journal Article] Microsecond Dynamics of a Protein by Single-Molecule Fluorescence Measurements2014
- Author(s)
  小井川浩之、齊藤雅嵩、高橋聡
- Journal Title
  
  Seibutsu Butsuri
  
  Volume: 54 Issue: 5 Pages: 276-279
- DOI
  10.2142/biophys.54.276
- NAID
  130004693958
- ISSN
  0582-4052, 1347-4219
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-25104007, KAKENHI-PROJECT-26282213, KAKENHI-PROJECT-26650045
[Journal Article] Microsecond dynamics of an unfolded protein by a line confocal tracking of single molecule fluorescence2013
- Author(s)
  Oikawa, H., Suzuki, Y., Saito, M., Kamagata, K., Arai, M., & Takahashi, S.
- Journal Title
  
  Scientific Reports
  
  Volume: 3 Issue: 1 Pages: 2151-2151
- DOI
  10.1038/srep02151
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23570188, KAKENHI-PROJECT-23657097, KAKENHI-PUBLICLY-24113701, KAKENHI-PLANNED-25104007, KAKENHI-PUBLICLY-25117504
[Presentation] Structural characterization of RNA upon the binding with SARS-CoV-2 N protein by single molecule fluorescence measurements2021
- Author(s)
  鈴木怜和, 小井川浩之, 高橋聡
- Organizer
  第59回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-19K06577
[Presentation] Single-molecule study of conformational dynamics of Intrinsically disordered E. coli Cytidine Repressor DNA Binding domain2021
- Author(s)
  Shrutarshi Mitra, Hiroyuki Oikawa, Athi N. Naganathan, Satoshi Takahashi
- Organizer
  第21回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-19K06577
[Presentation] Single molecule fluorescence investigations on the structure transitions of LAF-1 RGG upon the RNA binding and the droplet formation2021
- Author(s)
  藤田かんな, 木村美智子, 高橋泰人, 高橋聡, 小井川浩之
- Organizer
  第59回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-19K06577
[Presentation] Characterization of molecular uptake and single-molecule dynamics in liquid droplets of p532021
- Author(s)
  岩城奈那子, 上林さおり, Trishit Banerjee, 千葉梨佳, 木村美智子, 小井川浩之, 高橋聡, 鎌形清人
- Organizer
  第59回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-19K06577
[Presentation] Conformational properties of the intrinsically-disordered RGG domain of LAF-1 detected by single-molecule fluorescence spectroscopy2020
- Author(s)
  木村美智子, 中野沙耶, 高橋泰人, 小井川浩之, 高橋聡
- Organizer
  第58回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-19K06577
[Presentation] 天然変性タンパク質 LAF-1RGG ドメインの一分子蛍光分光測定による構造特性評価2020
- Author(s)
  木村美智子, 中野沙耶, 高橋泰人, 小井川浩之, 高橋聡
- Organizer
  分子科学会オンライン討論会
- Data Source
  KAKENHI-PROJECT-19K06577
[Presentation] Dynamics of the helix-coil transition of alanine-based polypeptides detected by nanosecond region fluorescence correlation spectroscopy2019
- Author(s)
  Supawich Kamonprasertsuk, Hiroyuki Oikawa, Satoshi Takahashi
- Organizer
  第57回日本生物物理学会年会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06577
[Presentation] Microsecond-resolved observation of F1-ATPase conformational changes by single molecular fluorescence spectroscopy2019
- Author(s)
  Hiroki Senmaru, Hiroyuki Oikawa, Mitsuhiro Sugawa, Satoshi Takahashi
- Organizer
  第57回日本生物物理学会年会
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04533
[Presentation] Dynamics of the helix-coil transition of alanine-based polypeptides detected by nanosecond region fluorescence correlation spectroscopy2019
- Author(s)
  Supawich Kamonprasertsuk, Hiroyuki Oikawa, Satoshi Takahashi
- Organizer
  第57回日本生物物理学会年会
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04533
[Presentation] Dynamics of the helix-coil transition of alanine-based polypeptides detected by nanosecond region fluorescence correlation spectroscopy2019
- Author(s)
  Supawich Kamonprasertsuk, Hiroyuki Oikawa, Satoshi Takahashi
- Organizer
  第13回分子科学討論会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06577
[Presentation] 一分子測定によって明らかにする液液相分離のメカニズム2019
- Author(s)
  木村美智子，小井川浩之, 高橋聡
- Organizer
  日本生物物理学会東北支部会2019
- Data Source
  KAKENHI-PUBLICLY-18H04533
[Presentation] Dynamics of the Helix-Coil Transition of Alanine-based Polypeptides Detected by Nanosecond Region Fluorescence Correlation Spectroscopy2019
- Author(s)
  Supawich Kamonprasertsuk, Hiroyuki Oikawa, Satoshi Takahashi
- Organizer
  Indo-Japan mini-workshop, Frontiers in Molecular Spectroscopy: From Fundamentals to Applications in Chemistry and Biology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06577
[Presentation] 一分子測定によって明らかにする液液相分離のメカニズム2019
- Author(s)
  木村美智子，小井川浩之, 高橋聡
- Organizer
  日本生物物理学会東北支部会2019
- Data Source
  KAKENHI-PROJECT-19K06577
[Presentation] Dynamics of the helix-coil transition of alanine-based polypeptides detected by nanosecond region fluorescence correlation spectroscopy2019
- Author(s)
  Supawich Kamonprasertsuk, Hiroyuki Oikawa, Satoshi Takahashi
- Organizer
  第13回分子科学討論会
- Data Source
  KAKENHI-PUBLICLY-18H04533
[Presentation] Microsecond-resolved observation of F1-ATPase conformational changes by single molecular fluorescence spectroscopy2019
- Author(s)
  Hiroki Senmaru, Hiroyuki Oikawa, Mitsuhiro Sugawa, Satoshi Takahashi
- Organizer
  第57回日本生物物理学会年会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06577
[Presentation] Dynamics of the Helix-Coil Transition of Alanine-based Polypeptides Detected by Nanosecond Region Fluorescence Correlation Spectroscopy2019
- Author(s)
  Supawich Kamonprasertsuk, Hiroyuki Oikawa, Satoshi Takahashiy Nanosecond Region Fluorescence Correlation Spectroscopy
- Organizer
  Indo-Japan mini-workshop, Frontiers in Molecular Spectroscopy: From Fundamentals to Applications in Chemistry and Biology
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04533
[Presentation] Single molecule fluorescence tracking at 10-μs resolution: Application to protein folding and functional dynamics2018
- Author(s)
  Satoshi Takahashi、Hiroyuki Oikawa
- Organizer
  第56回日本生物物理学会年会
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04533
[Presentation] Improvement of the fluorescent detected phage sorter for the application to phage display2018
- Author(s)
  Hitomi Urabe、Saya Nakano、Yuki Shimizu、Naoki Mikosiba、Hiroyuki Oikawa、Satoshi Takahashi
- Organizer
  第56回日本生物物理学会年会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K17608
[Presentation] マイクロ秒分解一分子蛍光測定によるF1-ATPaseの構造変化追跡2018
- Author(s)
  高橋巧、小井川浩之、須河光弘、高橋聡
- Organizer
  第18回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-17K17608
[Presentation] 単一分子蛍光分光法のための新しいタンパク質二重蛍光色素標識方法2018
- Author(s)
  吉田文、金沢省、高橋泰人、松井敏高、小井川浩之、浜田大三、高橋聡
- Organizer
  第18回日本蛋白質科学会年会
- Data Source
  KAKENHI-PUBLICLY-18H04533
[Presentation] Improvement of the fluorescent detected phage sorter for the application to phage display2018
- Author(s)
  Hitomi Urabe、Saya Nakano、Yuki Shimizu、Naoki Mikosiba、Hiroyuki Oikawa、Satoshi Takahashi
- Organizer
  第56回日本生物物理学会年会
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04533
[Presentation] Investigation on the structural properties of proteins included in non-membraneous granule droplets2018
- Author(s)
  Saya Nakano、Hiroyuki Oikawa、Satoshi Takahashi
- Organizer
  第56回日本生物物理学会年会
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04533
[Presentation] Investigation on the structural properties of proteins included in non-membraneous granule droplets2018
- Author(s)
  Saya Nakano、Hiroyuki Oikawa、Satoshi Takahashi
- Organizer
  第56回日本生物物理学会年会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K17608
[Presentation] Ultra-fast dynamics of simple polyalanine peptides by using nanosecond region fluorescence correlation spectroscopy2018
- Author(s)
  Supawich Kamonprasertsuk、Hiroyuki Oikawa、Satoshi Takahashi
- Organizer
  第56回日本生物物理学会年会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K17608
[Presentation] Single molecule fluorescence tracking at 10-μs resolution: Application to protein folding and functional dynamics2018
- Author(s)
  Satoshi Takahashi、Hiroyuki Oikawa
- Organizer
  第56回日本生物物理学会年会
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K17608
[Presentation] Ultra-fast dynamics of simple polyalanine peptides by using nanosecond region fluorescence correlation spectroscopy2018
- Author(s)
  Supawich Kamonprasertsuk、Hiroyuki Oikawa、Satoshi Takahashi
- Organizer
  第56回日本生物物理学会年会
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04533
[Presentation] 単一分子蛍光分光法のための新しいタンパク質二重蛍光色素標識方法2018
- Author(s)
  吉田文、金沢省、高橋泰人、松井敏高、小井川浩之、浜田大三、高橋聡
- Organizer
  第18回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-17K17608
[Presentation] マイクロ秒分解一分子蛍光測定によるF1-ATPaseの構造変化追跡2018
- Author(s)
  高橋巧、小井川浩之、須河光弘、高橋聡
- Organizer
  第18回日本蛋白質科学会年会
- Data Source
  KAKENHI-PUBLICLY-18H04533
[Presentation] Unexpected heterogeneity and slow dynamics of simple poly-alanine peptides detected by single molecule fluorescence spectroscopy2017
- Author(s)
  Supawich Kamonprasertsuk、Hiroyuki Oikawa、Satoshi Takahashi
- Organizer
  第55回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-17K17608
[Presentation] Dynamics of protein folding studied by single molecule fluorescence measurements at microsecond resolution2017
- Author(s)
  Satoshi Takahashi, Masataka Saito, Hiroyuki Oikawa
- Organizer
  Dijon workshop: Deciphering complex energy landscape and kinetic network from single molecules to cells: A new challenge to make theories meet experiments
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-25104007
[Presentation] Development of Fluorescence Correlation Spectrometer for the Elucidation of Protein Interactions2017
- Author(s)
  Asami Izaki、Hiroyuki Oikawa、Takeshi Tomita、Satoshi Takahashi
- Organizer
  第55回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-17K17608
[Presentation] タンパク質構造変化の遷移経路追跡を目指した一分子蛍光測定装置の開発2017
- Author(s)
  小井川浩之、高橋巧、須河光弘、高橋聡
- Organizer
  第11回分子科学討論会
- Data Source
  KAKENHI-PROJECT-17K17608
[Presentation] ライン共焦点顕微鏡によるタンパク質の構造形成運動の一分子蛍光観察2016
- Author(s)
  高橋聡、齊藤雅嵩、鎌形清人、小井川浩之
- Organizer
  第10回分子科学討論会
- Place of Presentation
  兵庫県神戸市（神戸ファッションマート）
- Year and Date
  2016-09-13
- Invited
- Data Source
  KAKENHI-PLANNED-25104007
[Presentation] Dynamics of protein folding studied by single molecule fluorescence measurements at microsecond resolution2016
- Author(s)
  Satoshi Takahashi, Masataka Saito, Kiyoto Kamagata and Hiroyuki OIkawa
- Organizer
  Recent Advances in Molecular Spectroscopy: Fundamentals and Applications in Materials and Biolgy 2016
- Place of Presentation
  インド・ハイデラバード
- Year and Date
  2016-03-02
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-25104007
[Presentation] Dynamics of protein folding studied by single molecule fluorescence measurements at microsecond resolution2016
- Author(s)
  Satoshi Takahashi, Masataka Saito and Hiroyuki Oikawa
- Organizer
  Indo-Japan Meeting, Frontiers in Molecular Spectroscopy:From Fundamentals to Applications on Material Science and Biology
- Place of Presentation
  インド・カーンプル
- Year and Date
  2016-11-13
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-25104007
[Presentation] Dynamics of protein folding studied by single molecule fluorescence measurements at microsecond resolution2016
- Author(s)
  Satoshi Takahashi, Masataka Saito and Hiroyuki Oikawa
- Organizer
  The Third International Symposium on Protein Folding and Dynamis
- Place of Presentation
  インド・バンガロール
- Year and Date
  2016-11-08
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-25104007
[Presentation] 1分子FRET測定によるシャペロニンGroELのおりたたみ補助機構の解明2016
- Author(s)
  松田智紗・吉田文・元島史尋・小井川浩之・鎌形清人・吉田賢右・高橋聡
- Organizer
  日本化学会第96春季年会
- Place of Presentation
  京都府京田辺市・同志社大学
- Year and Date
  2016-03-24
- Data Source
  KAKENHI-PLANNED-25104007
[Presentation] 一分子蛍光分光法によって観測されたユビキチンの変性状態の不均一性2015
- Author(s)
  齊藤雅嵩、Chen　Eric H.-L., Chen　Po-Ting, Chen　Rita P.-Y., 鎌形清人, 小井川浩之, 高橋聡
- Organizer
  第53回日本生物物理学会年会
- Place of Presentation
  石川県金沢市・金沢大学
- Year and Date
  2015-09-13
- Data Source
  KAKENHI-PLANNED-25104007
[Presentation] Tracking microsecond single-molecule FRET dynamics on the fast protein folding by the line-confocal microscopy2015
- Author(s)
  Hiroyuki Oikawa, Munehito Arai, Atsuhito Fukasawa, Hiroaki Yokota , Toru Ide , Satoshi Takahashi
- Organizer
  第53回日本生物物理学会年会
- Place of Presentation
  石川県金沢市・金沢大学
- Year and Date
  2015-09-13
- Data Source
  KAKENHI-PLANNED-25104007
[Presentation] Dynamiccs of protein folding studied by single molecule fluorescence time series measurements at microsecond resolution2015
- Author(s)
  Satsohi Takahashi, Masataka Saito, Kiyoto Kamagata and Hiroyuki Oikawa
- Organizer
  39th Annual ASB Conference
- Place of Presentation
  オーストラリア・アーミデール
- Year and Date
  2015-11-22
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-25104007
[Presentation] Complex folding transition of the B domain of protein A investigated by the high-speed measurement of single-molecule FRET time series2015
- Author(s)
  Hiroyuki Oikawa, Kiyoto Kamagata, Munehito Arai and Satsohi Takahashi
- Organizer
  PACIFICHEM 2015
- Place of Presentation
  米国・ハワイ
- Year and Date
  2015-12-15
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-25104007
[Presentation] マイクロ秒分解一分子FRET測定よるタンパク質折り畳みダイナミクスの追跡2015
- Author(s)
  小井川浩之,　新井宗仁,　深澤宏仁,　横田浩章,　井出徹,　高橋聡
- Organizer
  第9回分子科学討論会
- Place of Presentation
  東京都大田区・東京工業大学
- Year and Date
  2015-09-16
- Data Source
  KAKENHI-PLANNED-25104007
[Presentation] ユビキチンの折り畳みダイナミクスの一分子蛍光分光測定2015
- Author(s)
  齊藤雅嵩, Chen Eric H.-L., Chen Po-Ting, Chen Rita P.-Y., 鎌形清人,　小井川浩之,　高橋聡
- Organizer
  第9回分子科学討論会
- Place of Presentation
  東京都大田区・東京工業大学
- Year and Date
  2015-09-16
- Data Source
  KAKENHI-PLANNED-25104007
[Presentation] Rapid sample flow strategy for the ultrafast tracking of single molecule fluorescence time series2015
- Author(s)
  Satsohi Takahashi and Hiroyuki Oikawa
- Organizer
  PACIFICHEM 2015
- Place of Presentation
  米国・ハワイ
- Year and Date
  2015-12-15
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-25104007
[Presentation] Development of the line confocal system for the single-molecule tracking of the protein folding transition2014
- Author(s)
  Hiroyuki Oikawa
- Organizer
  International Workshop "Over the Barriers of Transition Paths: Dynamical Processes in Proteins and Complex Molecular Systems"
- Place of Presentation
  神奈川県横浜市
- Year and Date
  2014-06-28
- Invited
- Data Source
  KAKENHI-PLANNED-25104007
[Presentation] Improvements of the line confocal system for the single molecule tracking of fast folding dynamics of the B domain of protein A2013
- Author(s)
  Hiroyuki Oikawa, Kiyoto Kamagata, Munehito Arai, Satoshi Takahashi
- Organizer
  The 51th Annual Meeting of the Biophysical Society of Japan
- Place of Presentation
  京都府京都市
- Data Source
  KAKENHI-PLANNED-25104007
[Presentation] Investigation of p53’s Linker Region Role Using Single Molecule Fluorescence Microscopy2013
- Author(s)
  Toshihiko Kubota, Hiroyuki Oikawa, Kiyoto Kamagata, Satoshi Takahashi
- Organizer
  The 51th Annual Meeting of the Biophysical Society of Japan
- Place of Presentation
  京都府京都市
- Data Source
  KAKENHI-PLANNED-25104007
[Presentation] Microsecond dynamics of Ubiquitin folding detected by single molecule fluorescence spectroscopy2013
- Author(s)
  Masataka Saito, Hsin-Liang Chen, Rita P.-Y. Chen, Kiyoto Kamagata, Hiroyuki Oikawa, Satoshi Takahashi
- Organizer
  International Symposium for the 70th Anniversary of the Tohoku Branch of the Chemical Society of Japan
- Place of Presentation
  宮城県仙台市
- Data Source
  KAKENHI-PLANNED-25104007
[Presentation] Dynamics of ubiquitin folding detected by single molecule fluorescence spectroscopy2013
- Author(s)
  Masataka Saito, Chen Hsin-Liang, Chen Rita, Kiyoto Kamagata, Hiroyuki Oikawa, Satoshi Takahashi
- Organizer
  The 51th Annual Meeting of the Biophysical Society of Japan
- Place of Presentation
  京都府京都市
- Data Source
  KAKENHI-PLANNED-25104007
[Presentation] Microsecond-resolved Tracking of the Unfolded State of BdpA by a Line Confocal Detection of Single Molecule Fluorescence2013
- Author(s)
  Hiroyuki Oikawa, Yuta Suzuki, Masataka Saito, Kiyoto Kamagata, Munehito Arai, Satoshi Takahashi
- Organizer
  Technologies for Medical Diagnosis and Therapy Symposium
- Place of Presentation
  China, Taipei
- Data Source
  KAKENHI-PLANNED-25104007
[Presentation] 一分子蛍光分光法によるユビキチンの折り畳みダイナミクス
- Author(s)
  齊藤雅嵩・Chen Hsin-Liang・Chen Po-Ting・Chen Rita P.-Y.・鎌形清人・小井川浩之・高橋聡
- Organizer
  第14回日本蛋白質科学会年会
- Place of Presentation
  神奈川県横浜市
- Year and Date
  2014-06-25 – 2014-06-28
- Data Source
  KAKENHI-PLANNED-25104007
[Presentation] Development of a new strategy of protein design: the single phage sorting based on fluorescence intensity
- Author(s)
  Rie Kiriguchi, Toshihiko Kubota, Norihisa Takahashi, Seiji Sakamoto, Hiroyuki Oikawa, Kiyoto Kamagata , Takehiko Wada, Satoshi Takahashi
- Organizer
  第５２回日本生物物理学会年会
- Place of Presentation
  北海道札幌市
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PLANNED-25104007
[Presentation] タンパク質単分子の構造変化を計測する暗視野顕微鏡の開発
- Author(s)
  鎌形清人・間野絵梨子・七谷圭・阿蘇裕樹・井上裕一・小井川浩之・高橋聡
- Organizer
  第14回日本蛋白質科学会年会
- Place of Presentation
  神奈川県横浜市
- Year and Date
  2014-06-25 – 2014-06-28
- Data Source
  KAKENHI-PLANNED-25104007
[Presentation] Conformation of the denatured BFP bound to GroEL by single molecule FRET measurements
- Author(s)
  Aya Yoshida, Fumihiro Motojima, Hiroyuki OIkawa, Kiyoto Kamagata, Masasuke Yoshida and Satoshi Takahashi
- Organizer
  第５２回日本生物物理学会年会
- Place of Presentation
  北海道札幌市
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PLANNED-25104007
[Presentation] GroELに結合した基質BFPの一分子FRET計測による構造解析
- Author(s)
  吉田文・元島史尋・田口英樹・小井川浩之・鎌形清人・吉田賢右・高橋聡
- Organizer
  第14回日本蛋白質科学会年会
- Place of Presentation
  神奈川県横浜市
- Year and Date
  2014-06-25 – 2014-06-28
- Data Source
  KAKENHI-PLANNED-25104007
[Presentation] Development of the line confocal system for the single molecule tracking of fast folding dynamics of proteins
- Author(s)
  Hiroyuki Oikawa Kiyoto Kamagata, Munehito Arai, Atsuhito Fukasawa, Hiroaki Yokota, Toru Ide, Satoshi Takahashi
- Organizer
  第５２回日本生物物理学会年会
- Place of Presentation
  北海道札幌市
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PLANNED-25104007
[Presentation] Folding dynamics of ubiquitin after rapid mixing detected by single molecule fluorescence spectroscopy
- Author(s)
  Masataka Saito, Chen Erick, Chen Po-Ting, Chen Rita P.-Y., Kiyoto Kamagata, Hiroyuki Oikawa, Satoshi Takahashi
- Organizer
  第５２回日本生物物理学会年会
- Place of Presentation
  北海道札幌市
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PLANNED-25104007
[Presentation] 改良したマイクロ秒分解一分子蛍光測定法による蛋白質の高速折り畳みダイナミクスの追跡
- Author(s)
  小井川浩之・鎌形清人・新井宗仁・深澤宏仁・横田浩章・井出徹・高橋聡
- Organizer
  第14回日本蛋白質科学会年会
- Place of Presentation
  神奈川県横浜市
- Year and Date
  2014-06-25 – 2014-06-28
- Data Source
  KAKENHI-PLANNED-25104007
[Presentation] Development of The Line Confocal System for The Single Molecule Tracking of Folding Dynamics of Proteins
- Author(s)
  Hiroyuki Oikawa , Kiyoto Kamagata, Munehito Arai, Atuhito Fukasawa, Hiroaki Yokota, Toru Ide, Satoshi Takahashi
- Organizer
  Biophysical Society 59th Annual Meeting
- Place of Presentation
  Baltimore, USA
- Year and Date
  2015-02-07 – 2015-02-11
- Data Source
  KAKENHI-PLANNED-25104007
[Presentation] Microsecond-dynamics of the unfolded BdpA and ubiquitin by a line confocal detection of single molecule fluorescence
- Author(s)
  Hiroyuki Oikawa , Masataka Saito, Po-Ting Chen, Hsin-Liang Chen, Rita P.-Y. Chen, Munehito Arai, Kiyoto Kamagata, Satoshi Takahashi
- Organizer
  The 4th Asia Pacific Protein Association Conference
- Place of Presentation
  Jeju, Korea
- Year and Date
  2014-06-17 – 2014-06-20
- Data Source
  KAKENHI-PLANNED-25104007

1. Takahashi Satoshi (30283641)

# of Collaborated Projects: 2 results

# of Collaborated Products: 41 results
2. KAMAGATA Kiyoto (90432492)

# of Collaborated Projects: 1 results

# of Collaborated Products: 24 results
3. MANO Eriko

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. 新井宗仁

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
5. 高井まどか

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

OIKAWA Hiroyuki 小井川 浩之

Research Projects

Research Products

Co-Researchers

Tracking of protein conformational fluctuations in droplets of liquid-liquid phase separation by using single-molecule fluorescence spectroscopyPrincipal Investigator

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Tracking of protein conformational changes in crowded environments by using single-molecule fluorescence spectroscopyPrincipal Investigator

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Tracking of protein folding transition path by single-molecule fluorescence measurementsPrincipal Investigator

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Investigation on the dynamics of protein folding by single molecule fluorescence spectroscopy

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[Book] 相分離生物学の全貌（現代化学増刊46), 第Ⅵ部, 76節2020

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[Book] 「揺らぎ・ダイナミクスと生体機能～物理化学的視点から見た生体分子～」2013

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[Journal Article] Quantification of Entropic Excluded Volume Effects Driving Crowding-Induced Collapse and Folding of a Disordered Protein2022

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[Journal Article] Molecular principles of recruitment and dynamics of guest proteins in liquid droplets2021

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[Journal Article] Extracellular mRNA transported to the nucleus exerts translation-independent function2021

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[Journal Article] Hypothesis: structural heterogeneity of the unfolded proteins originating from the coupling of the local clusters and the long-range distance distribution2018

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[Journal Article] Microsecond resolved single-molecule FRET time series measurements based on the line confocal optical system combined with hybrid photodetectors2018

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[Journal Article] Highly Heterogeneous Nature of the Native and Unfolded States of the B Domain of Protein A Revealed by Two-Dimensional Fluorescence Lifetime Correlation Spectroscopy2017

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[Journal Article] Significant Heterogeneity and Slow Dynamics of the Unfolded Ubiquitin Detected by the Line Confocal Method of Single-Molecule Fluorescence Spectroscopy2016

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[Journal Article] Complexity of the folding transition of the B domain of protein A revealed by the high-speed tracking of single-molecule fluorescence time series2015

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[Journal Article] Where the complex things are: single molecule andensemble spectroscopic investigations of protein folding dynamics2015

Author(s)

OIKAWA Hiroyuki 小井川浩之