Shigematu Hideo 重松英朗

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SHIGEMATSU Hideo 重松英朗

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Researcher Number	40543707
Affiliation (Current)	2025: 広島大学, 原爆放射線医科学研究所, 講師
Affiliation (based on the past Project Information) *help	2023: 広島大学, 原爆放射線医科学研究所, 講師 2016 – 2022: 独立行政法人国立病院機構(呉医療センター臨床研究部), その他部局等, その他 2013 – 2015: 広島大学, 大学病院, 病院助教 2011 – 2012: 広島大学, 病院, 病院助教
Review Section/Research Field	Principal Investigator General surgery / Basic Section 55010:General surgery and pediatric surgery-related
Keywords	Principal Investigator 乳癌 / HER2 / breast cancer / non operation / 非切除療法 / 腫瘍免疫 / 乳房浮腫 / dormancy / 腫瘍微小環境 / 術前薬物療法 … More / Overall survival / Relapse free survival / Neoadjuvant chemotherapy / Peritumoral edema / Breast Cancer / Immune checkpoint / Tregの機能解析 / PD-L1 / Treg / breast / predictive factor / 二量体 / TS / 乳がん / 乳腺外科学 Less

Non operative approach for breast cancer by therapy-induced tumor dormancyPrincipal Investigator
- Principal Investigator
  
  Shigematsu Hideo
- Project Period (FY)
  2018 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Hiroshima University
  Department of Clinical Research, National Hospital Organization Kure Medical Center
targeting therapy of immunocheckpoint in HER2 positive breast cancerPrincipal Investigator
- Principal Investigator
  
  Shigematsu Hideo
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Department of Clinical Research, National Hospital Organization Kure Medical Center
  Hiroshima University
Evaluation of HER2 containing dimerzation for prediction of HER2-targeting therapyPrincipal Investigator
- Principal Investigator
  
  SHIGEMATSU Hideo
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General surgery
- Research Institution
  Hiroshima University
thymidylate synthase targeting therapy in HER2 positive breast cancerPrincipal Investigator
- Principal Investigator
  
  SHIGEMATSU Hideo
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General surgery
- Research Institution
  Hiroshima University

All 2023 2021 2020 2018 2017 2015 2014 2013 2012 Other

All Journal Article Presentation

[Journal Article] Omitting surgery for early breast cancer showing clinical complete response to primary systemic therapy2020
- Author(s)
  Hideo Shigematsu, Tomomi Fujisawa, Tadahiko Shien, Hiroji Iwata
- Journal Title
  
  Jpn J Clin Oncol
  
  Volume: 50(6) Issue: 6 Pages: 629-634
- DOI
  10.1093/jjco/hyaa055
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08585
[Journal Article] Comparison of CK-IHC assay on serial frozen sections, the OSNA assay, and in combination for intraoperative evaluation of SLN metastases in breast cancer.2017
- Author(s)
  Shigematsu Hideo
- Journal Title
  
  Breast Cancer
  
  Volume: 2 Issue: 2 Pages: 191-197
- DOI
  10.1007/s12282-017-0811-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K10053
[Journal Article] Clinical Significance of Extracapsular Invasion at Sentinel Lymph Nodes in Breast Cancer Patients with Sentinel Lymph Node Involvement2015
- Author(s)
  Hideo Shigematsu
- Journal Title
  
  Annal of Surgical Oncology
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25861155
[Journal Article] The efficacy and safety of preoperative chemotherapy with tri-weekly Abraxane and cyclophosphamide followed by 5-fluorouracil, epirubicin and cyclophosphamide therapy for resectable breast cancer; A multicenter clinical trial2015
- Author(s)
  Hideo Shigematsu
- Journal Title
  
  Clinical Breast Cancer
  
  Volume: 2 Issue: 2 Pages: 110-6
- DOI
  10.1016/j.clbc.2014.09.010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25861155
[Journal Article] Role of FDG-PET/CT in prediction of underestimation of invasive breast cancer in cases of ductal carcinoma in situ diagnosed at needle biopsy2014
- Author(s)
  Hideo Shigematsu
- Journal Title
  
  Clinical Breast Cancer
  
  Volume: 5 Issue: 5 Pages: 358-64
- DOI
  10.1016/j.clbc.2014.04.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25861155
[Presentation] Effect of neoadjuvant chemotherapy on peritumoral edema in breast cancer and its clinical significance2023
- Author(s)
  重松英朗
- Organizer
  第31回日本乳癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K08585
[Presentation] 乳癌術前化学療法のperitumoral edemaに対する効果とその臨床的意義2023
- Author(s)
  重松　英朗
- Organizer
  第31回日本乳癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K08585
[Presentation] Effect of neoadjuvant chemotherapy on peritumoral edema in early stage breast cancer and its prognostic value2023
- Author(s)
  Hideo Shigematsu
- Organizer
  San Antonio Breast Cancer Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08585
[Presentation] Peritumoral edemaによる術前化学療法が施行された乳癌の予後予測2021
- Author(s)
  重松英朗
- Organizer
  第122回日本外科学会
- Data Source
  KAKENHI-PROJECT-18K08585
[Presentation] 早期乳癌におけるTOP2A過剰発現および遺伝子増幅の臨床的意義についての検討2018
- Author(s)
  重松　英朗
- Organizer
  第26回日本乳癌学会学術総会
- Data Source
  KAKENHI-PROJECT-15K10053
[Presentation] PLA 法を用いた HER2 を含む二量体発現解析による HER2 標的療法の効果予測～基礎から臨床への応用～2013
- Author(s)
  重松英朗, 網岡愛, 梶谷桂子, 恵美純子、舛本法生,角舎学行,春田るみ,片岡健、尾田三世,有廣光司,岡田守人
- Organizer
  第113回日本外科学会
- Place of Presentation
  福岡
- Year and Date
  2013-04-11
- Data Source
  KAKENHI-PROJECT-23791485
[Presentation] PTEN発現およびHER2-2二量体発現解析に基づく術前trastuzumab療法効果予測の試み2013
- Author(s)
  重松英朗
- Organizer
  日本乳癌学会
- Place of Presentation
  浜松市
- Data Source
  KAKENHI-PROJECT-25861155
[Presentation] Expression levels of HER2-2 dimer in proximity ligation assays is associated with trastuzumab sensitivity in HER2-positive breast cancer2013
- Author(s)
  Hideo Shigematsu
- Organizer
  ESMO
- Place of Presentation
  オランダ、Amsterdam
- Data Source
  KAKENHI-PROJECT-25861155
[Presentation] PLA 法を用いたホルマリン固定標本における HER2 を含む二量体発現の解析方法の確立2012
- Author(s)
  重松英朗、角舎学行、片岡健、尾田三世、有廣光司、岡田守人
- Organizer
  第20回日本乳がん学会
- Place of Presentation
  熊本
- Year and Date
  2012-06-29
- Data Source
  KAKENHI-PROJECT-23791485
[Presentation] PLA 法を用いた HER2 を含む二量体発現解析に基づく HER2 標的療法の効果予測2012
- Author(s)
  重松英朗、秋本悦志、恵美純子、舛本法生、角舎学行、春田るみ、片岡健、尾田三世、有廣光司、岡田守人
- Organizer
  第50回癌治療学会
- Place of Presentation
  横浜
- Year and Date
  2012-10-26
- Data Source
  KAKENHI-PROJECT-23791485
[Presentation] Role of FDG-PET/CT in prediction of underestimation of invasive breast cancer in cases of ductal carcinoma in situ diagnosed at needle biopsy
- Author(s)
  Hideo Shigematsu
- Organizer
  San Antonio Breast Cancer Symposium
- Place of Presentation
  San Antonio, USA
- Year and Date
  2014-12-08 – 2014-12-11
- Data Source
  KAKENHI-PROJECT-25861155
[Presentation] PLA法を用いたHER2を含む二量体発現解析によるHER2標的療法の効果予測～基礎から臨床への応用～
- Author(s)
  重松英朗
- Organizer
  第113回日本外科学会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23791485
[Presentation] PLA法を用いたホルマリン固定標本におけるHER2を含む二量体発現の解析方法の確立
- Author(s)
  重松英朗
- Organizer
  第20回日本乳癌学会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-23791485
[Presentation] PLA法を用いたHER2を含む二量体発現解析に基づくHER2標的療法の効果予測
- Author(s)
  重松英朗
- Organizer
  第50回癌治療学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23791485

1. 岡田守人 (70446045)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 尾崎慎治 (10558266)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. OZAKI Shinji

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Shigematu Hideo 重松 英朗

SHIGEMATSU Hideo 重松 英朗

Research Projects

Research Products

Co-Researchers

Non operative approach for breast cancer by therapy-induced tumor dormancyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

targeting therapy of immunocheckpoint in HER2 positive breast cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Evaluation of HER2 containing dimerzation for prediction of HER2-targeting therapyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

thymidylate synthase targeting therapy in HER2 positive breast cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Omitting surgery for early breast cancer showing clinical complete response to primary systemic therapy2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Comparison of CK-IHC assay on serial frozen sections, the OSNA assay, and in combination for intraoperative evaluation of SLN metastases in breast cancer.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Clinical Significance of Extracapsular Invasion at Sentinel Lymph Nodes in Breast Cancer Patients with Sentinel Lymph Node Involvement2015

Author(s)

Journal Title

Data Source

[Journal Article] The efficacy and safety of preoperative chemotherapy with tri-weekly Abraxane and cyclophosphamide followed by 5-fluorouracil, epirubicin and cyclophosphamide therapy for resectable breast cancer; A multicenter clinical trial2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Role of FDG-PET/CT in prediction of underestimation of invasive breast cancer in cases of ductal carcinoma in situ diagnosed at needle biopsy2014

Author(s)

Journal Title

DOI

Data Source

[Presentation] Effect of neoadjuvant chemotherapy on peritumoral edema in breast cancer and its clinical significance2023

Author(s)

Organizer

Data Source

[Presentation] 乳癌術前化学療法のperitumoral edemaに対する効果とその臨床的意義2023

Author(s)

Organizer

Data Source

[Presentation] Effect of neoadjuvant chemotherapy on peritumoral edema in early stage breast cancer and its prognostic value2023

Author(s)

Organizer

Data Source

[Presentation] Peritumoral edemaによる術前化学療法が施行された乳癌の予後予測2021

Author(s)

Organizer

Data Source

[Presentation] 早期乳癌におけるTOP2A過剰発現および遺伝子増幅の臨床的意義についての検討2018

Author(s)

Organizer

Data Source

[Presentation] PLA 法を用いた HER2 を含む二量体発現解析による HER2 標的療法の効果予測～基礎から臨床への応用～2013

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] PTEN発現およびHER2-2二量体発現解析に基づく術前trastuzumab療法効果予測の試み2013

Shigematu Hideo 重松英朗

SHIGEMATSU Hideo 重松英朗