HANDA TAKASHI 半田高史

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Handa Takashi 半田高史

HANDA Takashi 半田高史

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Researcher Number	40567335
Other IDs	https://orcid.org/0000-0003-3956-8077
Affiliation (Current)	2026: 広島大学, 医系科学研究科(医), 准教授
Affiliation (based on the past Project Information) *help	2020 – 2025: 広島大学, 医系科学研究科(医), 助教 2013: 独立行政法人理化学研究所, 脳科学総合研究センター, 研究員 2012: 独立行政法人理化学研究所, 脳回路機能理論研究チーム, 研究員
Review Section/Research Field	Principal Investigator Basic Section 46030:Function of nervous system-related / Neuroscience in general Except Principal Investigator Basic Section 59010:Rehabilitation science-related / Basic Section 51010:Basic brain sciences-related
Keywords	Principal Investigator 大脳皮質 / 線条体 / 半球間抑制 / マウス / 光遺伝学 / テンソル分解 / 皮質ー線条体経路 / 神経活動 / 適応行動 / 国際情報交換 … More / 多細胞集団 / 行動選択 / ラット / 前頭前野 / ニューロン活動 / 神経生理 … More Except Principal Investigator 神経可塑性 / 静磁場刺激 / 半球間抑制 / リハビリテーション / 脳卒中 / 海馬 / データ同化 / 抑制性細胞 / 線条体 / 運動野 / 領野間通信 / 領野間相互作用 / 力学系理論 / 詳細局所神経回路モデル / リカレントニューラルネットワークモデル / 神経系の領野間通信 Less

左右の大脳皮質を対称・非対称につなぐ交連線維の半球間相互作用の機能的役割の解明Principal Investigator
- Principal Investigator
  
  半田高史
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 46030:Function of nervous system-related
- Research Institution
  Hiroshima University
Basic Research on Static Magnetic Field Stimulation and Interhemispheric Neural Activity Modulation in Stroke Rehabilitation.
- Principal Investigator
  
  高松泰行
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59010:Rehabilitation science-related
- Research Institution
  Chubu University
Neural mechanims underlying flexible choice behavior through two distinct cortico-striatal pathwaysPrincipal Investigator
- Principal Investigator
  
  Handa Takashi
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 46030:Function of nervous system-related
- Research Institution
  Hiroshima University
The mechanism of inter-areal communication in neural systems by neural trajectories
- Principal Investigator
  
  KURIKAWA Tomoki
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 51010:Basic brain sciences-related
- Research Institution
  Kansai Medical University
Role for pyramidal cells and interneurons in prefrontal cortex underlying decision making and output information to subcortical areasPrincipal Investigator
- Principal Investigator
  
  HANDA Takashi
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neuroscience in general
- Research Institution
  Institute of Physical and Chemical Research

All 2025 2024 2023 2022 2021 2014 2013 2012

All Journal Article Presentation

[Journal Article] Cell type-specific contribution to the initiation of cortical spreading depolarization in the mouse2025
- Author(s)
  Handa Takashi、Zhang Qing、Ma Zhongqi、Aizawa Hidenori
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 751 Pages: 151428-151428
- DOI
  10.1016/j.bbrc.2025.151428
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K06485, KAKENHI-PROJECT-23K18256
[Journal Article] Cholinergic modulation of interhemispheric inhibition in the mouse motor cortex2024
- Author(s)
  Takashi Handa, Qing Zhang, Hidenori Aizawa
- Journal Title
  
  bioRxiv
  
  Volume: -
- DOI
  10.1101/2024.02.05.579044
- Open Access
- Data Source
  KAKENHI-PROJECT-22K06485
[Journal Article] Decomposed frontal corticostriatal ensemble activity changes across trials, revealing distinct features relevant to outcome-based decision making2024
- Author(s)
  Takashi Handa, Tomoki Fukai, Tomoki Kurikawa
- Journal Title
  
  bioRxiv
  
  Volume: -
- DOI
  10.1101/2024.03.23.586395
- Open Access
- Data Source
  KAKENHI-PROJECT-22K06485
[Journal Article] Cholinergic modulation of interhemispheric inhibition in the mouse motor cortex2024
- Author(s)
  Handa Takashi、Zhang Qing、Aizawa Hidenori
- Journal Title
  
  Cerebral Cortex
  
  Volume: 34 Issue: 7 Pages: 1-18
- DOI
  10.1093/cercor/bhae290
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K06485, KAKENHI-PROJECT-23K18256
[Journal Article] Single-Trial Representations of Decision-Related Variables by Decomposed Frontal Corticostriatal Ensemble Activity2024
- Author(s)
  Handa Takashi、Fukai Tomoki、Kurikawa Tomoki
- Journal Title
  
  eNeuro
  
  Volume: 11 Issue: 8 Pages: 1-16
- DOI
  10.1523/eneuro.0172-24.2024
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23H05476, KAKENHI-PROJECT-22K06485
[Journal Article] 個体ごとの行動特性に関係する神経回路活動2023
- Author(s)
  半田高史
- Journal Title
  
  月刊「細胞」
  
  Volume: 55 Pages: 37-40
- Data Source
  KAKENHI-PROJECT-22K06485
[Journal Article] Concomitant Processing of Choice and Outcome in Frontal Corticostriatal Ensembles Correlates with Performance of Rats2021
- Author(s)
  Takashi Handa, Rie Harukuni, Tomoki Fukai
- Journal Title
  
  Cerebral Cortex
  
  Volume: - Issue: 9 Pages: 4357-4375
- DOI
  10.1093/cercor/bhab091
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07716, KAKENHI-PROJECT-18H05213
[Journal Article] Synergistic information in the frontal cortex-striatal pathway2021
- Author(s)
  Alsolami Ibrahim、Handa Takashi、Fukai Tomoki
- Journal Title
  
  bioRxiv
  
  Volume: -
- DOI
  10.1101/2021.06.18.449072
- Open Access
- Data Source
  KAKENHI-PROJECT-20K07716
[Journal Article] Modulation of neuronal activity with cue-invariant shape discrimination in the primate superior temporal sulcus2014
- Author(s)
  S. Unno, T. Handa, Y. Nagasaka, M. Inoue, A. Mikami
- Journal Title
  
  Neuroscience
  
  Volume: 268 Pages: 221-235
- URL
  http://www.sciencedirect.com/science/article/pii/S0306452214002371
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24700345
[Journal Article] Reward-modulated motor information in identified striatum neurons.2013
- Author(s)
  Yoshikazu Isomura, Takashi Takekawa, Rie Harukuni, Takashi Handa, Hidenori Aizawa, Masahiko Takada, and Tomoki Fukai
- Journal Title
  
  J. Neurosci.
  
  Volume: 33 Issue: 25 Pages: 10209-10220
- DOI
  10.1523/jneurosci.0381-13.2013
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22115013, KAKENHI-PUBLICLY-24120715, KAKENHI-PROJECT-24300143, KAKENHI-PROJECT-24700345, KAKENHI-PUBLICLY-25110716, KAKENHI-PROJECT-25250003, KAKENHI-PROJECT-25640011
[Presentation] マウス大脳皮質運動野における半球間抑制に与えるアセチルコリン神経修飾2025
- Author(s)
  半田高史、張晴、相澤秀紀
- Organizer
  APPW2025　第130回日本解剖学会・第102回日本生理学会・第98回日本薬理学会合同大会
- Data Source
  KAKENHI-PROJECT-22K06485
[Presentation] Cholinergic modulation of interhemispheric inhibition in the mouse motor cortex2024
- Author(s)
  Takashi Handa, Qing Zhang, Hidenori Aizawa
- Organizer
  Neuro2024, 2024/07/25, Japan Neuroscience Society, Japanese Society for Neurochemistry, Japanese Society of Biological Psychiatry
- Data Source
  KAKENHI-PROJECT-22K06485
[Presentation] アセチルコリンがマウス半球間抑制神経回路に与える神経修飾作用2024
- Author(s)
  半田高史、張晴、相澤秀紀
- Organizer
  第129回日本解剖学会総会・全国学術集会
- Data Source
  KAKENHI-PROJECT-22K06485
[Presentation] Dynamic single-trial representation of decision-related information by decomposed frontal cortico-striatal ensemble activity across trials2024
- Author(s)
  Takashi Handa
- Organizer
  日本動物心理学会第84回大会
- Data Source
  KAKENHI-PROJECT-22K06485
[Presentation] 行動課題進行中の大脳皮質前頭皮質－線条体回路活動パタンが表象する行動関連情報の動態2024
- Author(s)
  半田高史、栗川知己
- Organizer
  第101回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-22K06485
[Presentation] Single-trial representation of behavioral task related information by decomposed ensemble activity in rat frontal cortico-striatal circuit.2024
- Author(s)
  Takashi Handa
- Organizer
  日本比較生理生化学会第46回名古屋大会
- Data Source
  KAKENHI-PROJECT-22K06485
[Presentation] Cholinergic modulation fo interhemispheric interaction in the mouse motor cortex2023
- Author(s)
  Takashi Handa, Qing Zhang, Hidenori Aizawa
- Organizer
  The 2nd International Symposium HYPER-ADAPTABILITY
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06485
[Presentation] マウス半球間抑制神経回路に与えるアセチルコリン神経修飾の影響2023
- Author(s)
  半田高史、張晴、相澤秀紀
- Organizer
  第77 回中国・四国支部学術集会
- Data Source
  KAKENHI-PROJECT-22K06485
[Presentation] アセチルコリン神経伝達によるマウス大脳皮質運動野における半球間相互作用の修飾2023
- Author(s)
  半田高史、相澤秀紀
- Organizer
  第46回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-22K06485
[Presentation] テンソル分解による大脳皮質－線条体回路活動パタンの解析2023
- Author(s)
  半田高史
- Organizer
  第75回日本生理学会中国四国地方会
- Data Source
  KAKENHI-PROJECT-22K06485
[Presentation] マウス二次運動野における交連線維の光遺伝学的興奮によって誘発されるフィールド電位とスパイク発火特性への薬理学的影響2022
- Author(s)
  半田高史、相澤秀紀
- Organizer
  Neuro2022（日本神経科学学会・日本神経化学学会・日本神経回路学会の合同大会）
- Data Source
  KAKENHI-PROJECT-22K06485
[Presentation] ウス二次運動野における交連線維の光遺伝学的興奮によって誘発されるフィールド電位とスパイク発火特性への薬理学的影響2022
- Author(s)
  半田高史、相澤秀紀
- Organizer
  第４5回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-20K07716
[Presentation] Neural ensemble dynamics in rat dorsomedial prefrontal cortex during a sensory-guided choice task2013
- Author(s)
  Handa Takashi, Takekawa Takashi, Harukuni Rie, Isomura Yoshikazu, and Fukai Tomoki
- Organizer
  Neuro2013, P3-2-69, 2013
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-24700345
[Presentation] Neural ensemble dynamics in rat dorsomedial prefrontal cortex during probabilistic sensory-cued choice2013
- Author(s)
  Handa Takashi, Takekawa Takashi, Harukuni Rie, Isomura Yoshikazu, Fukai Tomoki.
- Organizer
  Bernstein Conference
- Place of Presentation
  Tuebingen, Germany
- Data Source
  KAKENHI-PROJECT-24700345
[Presentation] Neural ensemble dynamics in rat dorsomedial prefrontal cortex during a sensory-guided choice task2013
- Author(s)
  Handa Takashi, Takekawa Takashi, Harukuni Rie, Isomura Yoshikazu, Fukai Tomoki
- Organizer
  Neuro2013
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-24700345
[Presentation] Neural ensemble dynamics in rat dorsomedial prefrontal cortex during probabilistic sensory-cued choice2013
- Author(s)
  Handa Takashi, Takekawa Takashi, Harukuni Rie, Isomura Yoshikazu, and Fukai Tomoki
- Organizer
  Bernstein Conference, poster W65, 2013
- Place of Presentation
  Tuebingen, Germany
- Data Source
  KAKENHI-PROJECT-24700345
[Presentation] Representation of sensory feature and spatial choice in dorsomedial prefrontal cortex of rat making action decision using sensory information2012
- Author(s)
  Handa Takashi, Takekawa Takashi, Harukuni Rie, Isomura Yoshikazu, and Fukai Tomoki
- Organizer
  Society for Neuroscience
- Place of Presentation
  New Orleans, U.S.A.(Abstract, 38:811.06, 2012)
- Data Source
  KAKENHI-PROJECT-24700345
[Presentation] Cell type-specific activity in rodent prefrontal cortex for making action decision using novel information2012
- Author(s)
  Handa Takashi, Takekawa Takashi, Harukuni Rie, Isomura Yoshikazu, and Fukai Tomoki
- Organizer
  The 8th Federation of European Neuroscience Society Forum, 22.10, 2012
- Place of Presentation
  Barcelona, Spain
- Data Source
  KAKENHI-PROJECT-24700345
[Presentation] Cell type-specific activity in rodent prefrontal cortex for making action decision using novel information.2012
- Author(s)
  Handa Takashi, Takekawa Takashi, Harukuni Rie, Isomura Yoshikazu, and Fukai Tomoki.
- Organizer
  The 8th Federation of European Neuroscience Society Forum
- Place of Presentation
  Barcelona, Spain
- Data Source
  KAKENHI-PROJECT-24700345
[Presentation] Representation of sensory feature and spatial choice in dorsomedial prefrontal cortex of rat making action decision using sensory information.2012
- Author(s)
  Handa Takashi, Takekawa Takashi, Harukuni Rie, Isomura Yoshikazu, and Fukai Tomoki.
- Organizer
  Society for Neuroscience　(Neuroscience2012)
- Place of Presentation
  New Orleans, U.S.A.
- Data Source
  KAKENHI-PROJECT-24700345

1. KURIKAWA Tomoki (20741333)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 高松泰行 (40802096)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. TAKEKAWA Takashi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 深井朋樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

HANDA TAKASHI 半田 高史

Handa Takashi 半田 高史

HANDA Takashi 半田 高史

Research Projects

Research Products

Co-Researchers

左右の大脳皮質を対称・非対称につなぐ交連線維の半球間相互作用の機能的役割の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Basic Research on Static Magnetic Field Stimulation and Interhemispheric Neural Activity Modulation in Stroke Rehabilitation.

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Neural mechanims underlying flexible choice behavior through two distinct cortico-striatal pathwaysPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The mechanism of inter-areal communication in neural systems by neural trajectories

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Role for pyramidal cells and interneurons in prefrontal cortex underlying decision making and output information to subcortical areasPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Cell type-specific contribution to the initiation of cortical spreading depolarization in the mouse2025

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cholinergic modulation of interhemispheric inhibition in the mouse motor cortex2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Decomposed frontal corticostriatal ensemble activity changes across trials, revealing distinct features relevant to outcome-based decision making2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cholinergic modulation of interhemispheric inhibition in the mouse motor cortex2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Single-Trial Representations of Decision-Related Variables by Decomposed Frontal Corticostriatal Ensemble Activity2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 個体ごとの行動特性に関係する神経回路活動2023

Author(s)

Journal Title

Data Source

[Journal Article] Concomitant Processing of Choice and Outcome in Frontal Corticostriatal Ensembles Correlates with Performance of Rats2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Synergistic information in the frontal cortex-striatal pathway2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Modulation of neuronal activity with cue-invariant shape discrimination in the primate superior temporal sulcus2014

Author(s)

Journal Title

URL

Data Source

HANDA TAKASHI 半田高史

Handa Takashi 半田高史

HANDA Takashi 半田高史