ISHII Hiroki 石井裕貴

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Ishii Hiroki 石井裕貴

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Researcher Number	40568250
Other IDs
Affiliation (Current)	2025: 山梨大学, 大学院総合研究部, 講師
Affiliation (based on the past Project Information) *help	2020 – 2024: 山梨大学, 大学院総合研究部, 講師 2017 – 2018: 山梨大学, 大学院総合研究部, 助教 2014 – 2016: 山梨大学, 総合研究部, 助教 2014: 山梨大学, 総合研究部, 診療助教 2013: 山梨大学, 医学工学総合研究部, 助教 2012: 山梨大学, 医学部附属病院, 助教
Review Section/Research Field	Principal Investigator Basic Section 56050:Otorhinolaryngology-related / Otorhinolaryngology Except Principal Investigator Basic Section 56050:Otorhinolaryngology-related / Otorhinolaryngology / Basic Section 90130:Medical systems-related
Keywords	Principal Investigator パクリタキセル / 頭頸部癌 / ESRP1 / がん免疫療法 / 抗がん剤耐性 / Slug / 遠隔転移 / 骨髄系免疫抑制細胞 / 代謝解析 / MDSC … More / 一次代謝産物 / 免疫修飾 / 酸化的リン酸化 / ATP / 免疫原性細胞死 / MDSCs / 炎症 / IL-1b / CD44 / EMT関連転写因子 / 選択的RNAスプライシング / ESRP2 / dEF1/SIP1 / Rac1b / RNA splicing / EMT / ESRP1/2 … More Except Principal Investigator 花粉症 / アレルギー性鼻炎 / 低用量抗がん剤 / 樹状細胞 / ディープラーニング / 診断支援装置 / 機械学習 / 生体音 / 嚥下音 / 筋電図 / 超音波動画像 / 嚥下 / リスク因子 / 発症機序 / 発症因子 / 小児 / T細胞 / エピゲノム / 遺伝子 / IL-12 / 低用量ドセタキセル / 頭頸部癌 / 樹状細胞療法 / 癌免疫療法 / 抗がん剤耐性 / 低容量抗がん剤 / 頭頸部がん / がん免疫療法 Less

Establishing therapeutic strategy of taxol based chemo-immunotherapy for head and neck cancerPrincipal Investigator
- Principal Investigator
  
  石井裕貴
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  University of Yamanashi
急増する小児アレルギー性鼻炎の発症リスク因子と発症機序の解明に向けた研究
- Principal Investigator
  
  櫻井大樹
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  University of Yamanashi
超音波動画像と筋電図と嚥下音を用いた非侵襲計測による嚥下評価のための装置開発研究
- Principal Investigator
  
  鈴木裕
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 90130:Medical systems-related
- Research Institution
  Toyo University
Immunometabolism-targeted cancer therapy in HNSCCPrincipal Investigator
- Principal Investigator
  
  Ishii Hiroki
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  University of Yamanashi
The study of epigenetic regulation in peripheral immune cells associated with onset and remission of allergic rhinitis.
- Principal Investigator
  
  SAKURAI DAIJU
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  University of Yamanashi
  Chiba University
Development of dendritic cell-based cancer chemoimmunotherapy in head and neck caner to target inflammatory tumor microenvironment
- Principal Investigator
  
  MASUYAMA Keisuke
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  University of Yamanashi
RNAスプライシングを介したEMT制御の転移性頭頸部がん治療への応用にむけた研究Principal Investigator
- Principal Investigator
  
  石井裕貴
- Project Period (FY)
  2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  University of Yamanashi
Establishment of DC immunotherapy with low-dose chemotherapy in HNSCC
- Principal Investigator
  
  MASUYAMA Keisuke
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  University of Yamanashi
Functional characterization of ESRP1 and 2 in HNSCC.Principal Investigator
- Principal Investigator
  
  ISHII Hiroki
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  University of Yamanashi

All 2023 2022 2017 2015 2014 Other

All Journal Article Presentation Other

[Journal Article] スギ・ヒノキ花粉観測25年間の報告　山梨県における地域差と年次推移の検討2023
- Author(s)
  島村歩美, 代永孝明, 渡邉大輔, 五十嵐賢, 石井裕貴, 松岡伴和, 増山敬祐, 櫻井大樹
- Journal Title
  
  日本耳鼻咽喉科免疫アレルギー感染症学会誌
  
  Volume: 3 Pages: 2435-7952
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K09740
[Journal Article] Genomic and immune microenvironment profiling in a case of metastatic intrathyroid thymic carcinoma2022
- Author(s)
  Ishii Hiroki、Tsujikawa Takahiro、Oishi Naoki、Kinouchi Arisa、Sakamoto Kaname、Mitsuda Junichi、Ogi Hiroshi、Itoh Kyoko、Kondo Tetsuo、Hirano Shigeru、Sakurai Daiju
- Journal Title
  
  Clinical Case Reports
  
  Volume: 10 Issue: 7
- DOI
  10.1002/ccr3.6050
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06883, KAKENHI-PROJECT-22K09688, KAKENHI-PROJECT-20K09706
[Journal Article] Sublingual Immunotherapy for Japanese Cedar Pollinosis: Current Clinical and Research Status2022
- Author(s)
  Sakurai Daiju、Ishii Hiroki、Shimamura Ayumi、Watanabe Daisuke、Yonaga Takaaki、Matsuoka Tomokazu
- Journal Title
  
  Pathogens
  
  Volume: 11 Issue: 11 Pages: 1313-1313
- DOI
  10.3390/pathogens11111313
- Data Source
  KAKENHI-PROJECT-20K09706
[Journal Article] Establishment of Synergistic Chemoimmunotherapy for Head and Neck Cancer Using Peritumoral Immature Dendritic Cell Injections and Low-Dose Chemotherapies.2017
- Author(s)
  Ishii H, Chikamatsu K, Igarashi S, Takahashi H, Sakamoto K, Higuchi H, Tanaka S, Matsuoka T, Masuyama K.
- Journal Title
  
  Translational Oncology
  
  Volume: 11(1) Issue: 1 Pages: 132-139
- DOI
  10.1016/j.tranon.2017.11.006
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K10806, KAKENHI-PROJECT-17K11374
[Journal Article] Therapeutic strategy for cancer immunotherapy in head and neck cancer2015
- Author(s)
  Hiroki Ishii, Shota Tanaka, Keisuke Masuyama.
- Journal Title
  
  Advances in Cellular and Molecular Otolaryngology
  
  Volume: 3 Issue: 1 Pages: 1-12
- DOI
  10.3402/acmo.v3.27690
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K20197
[Journal Article] Epithelial Splicing Regulatory Protein 1 (ESRP1) and 2 (ESRP2) Suppress Cancer Cell Motility via Different Mechanisms2014
- Author(s)
  Hiroki Ishii, Masao Saitoh, Kei Sakamoto, Tetsuo Kondo, Ryohei Katoh, Shota Tanaka, Mitsuyoshi Motizuki, Keisuke Masuyama, Keiji Miyazawa
- Journal Title
  
  The journal of biological chemistry
  
  Volume: 289(40) Issue: 40 Pages: 27386-99
- DOI
  10.1074/jbc.m114.589432
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24592592, KAKENHI-PROJECT-24791764, KAKENHI-PROJECT-25293087
[Presentation] タキサン系抗がん剤による免疫修飾から考える新たな頭頸部癌治療戦略2022
- Author(s)
  石井裕貴
- Organizer
  第46回日本頭頸部癌学会
- Data Source
  KAKENHI-PROJECT-20K09706
[Presentation] DOWN-REGULATION OF ESRP1 TRIGGERS CELL INVASION THROUGH DE-REPRESSION OF RAC1B IN HNSCC2014
- Author(s)
  Hiroki Ishii
- Organizer
  IFHNOS 2014 5th World Congress & AHNS Annual Meeting
- Place of Presentation
  the Marriott Marquis Hotel in Times Square in New York (米国)
- Data Source
  KAKENHI-PROJECT-24791764
[Presentation] ESRP1は腫瘍特異的Rac1bを抑制し、がん細胞の運動能を制御する2014
- Author(s)
  石井裕貴
- Organizer
  第18回日本がん分子標的治療学会学術集会
- Place of Presentation
  仙台市情報・産業プラザ　セミナールーム2 (宮城県仙台市)
- Data Source
  KAKENHI-PROJECT-24791764
[Presentation] DOWN-REGULATION OF ESRP1 TRIGGERS CELL INVASION THROUGH DE-REPRESSION OF RAC1B IN HNSCC
- Author(s)
  Hiroki Ishii, Keisuke Masuyama
- Organizer
  5th IFHNOS World Congress 2014
- Place of Presentation
  ニューヨーク(アメリカ）
- Year and Date
  2014-07-27 – 2014-07-30
- Data Source
  KAKENHI-PROJECT-24791764
[Presentation] ESRP1,ESRP2 は異なる機序でがん細胞の運動能を制御する
- Author(s)
  石井裕貴、齋藤正夫、増山敬祐、宮澤恵二
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜(神奈川県　横浜市)
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-24791764
[Presentation] ESRP1は腫瘍特異的RAC1bを抑制し、がん細胞の運動能を制御する
- Author(s)
  石井裕貴、齋藤正夫、宮澤恵二
- Organizer
  第18回日本がん分子標的治療学会
- Place of Presentation
  仙台市産業・情報プラザ(宮城県　仙台市)
- Year and Date
  2014-06-24 – 2014-06-26
- Data Source
  KAKENHI-PROJECT-24791764
[]

1. SAKURAI DAIJU (10375636)

# of Collaborated Projects: 4 results

# of Collaborated Products: 2 results
2. MASUYAMA Keisuke (30181663)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
3. 五十嵐賢 (10597016)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. 吉村健太郎 (70516921)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 金田篤志 (10313024)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 鈴木裕 (40516928)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 駒形純也 (20712798)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 阪田治 (30391197)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 笹沼里圭子 (30982582)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 谷本守正 (60621323)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 小谷信司 (80242618)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 小佐野雅識 (20622426)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 高橋真理 (30622427)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 大石直輝

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

ISHII Hiroki 石井 裕貴

Ishii Hiroki 石井 裕貴

Research Projects

Research Products

Co-Researchers

Establishing therapeutic strategy of taxol based chemo-immunotherapy for head and neck cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

急増する小児アレルギー性鼻炎の発症リスク因子と発症機序の解明に向けた研究

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

超音波動画像と筋電図と嚥下音を用いた非侵襲計測による嚥下評価のための装置開発研究

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Immunometabolism-targeted cancer therapy in HNSCCPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The study of epigenetic regulation in peripheral immune cells associated with onset and remission of allergic rhinitis.

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of dendritic cell-based cancer chemoimmunotherapy in head and neck caner to target inflammatory tumor microenvironment

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

RNAスプライシングを介したEMT制御の転移性頭頸部がん治療への応用にむけた研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Establishment of DC immunotherapy with low-dose chemotherapy in HNSCC

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Functional characterization of ESRP1 and 2 in HNSCC.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] スギ・ヒノキ花粉観測25年間の報告 山梨県における地域差と年次推移の検討2023

Author(s)

Journal Title

Data Source

[Journal Article] Genomic and immune microenvironment profiling in a case of metastatic intrathyroid thymic carcinoma2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Sublingual Immunotherapy for Japanese Cedar Pollinosis: Current Clinical and Research Status2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Establishment of Synergistic Chemoimmunotherapy for Head and Neck Cancer Using Peritumoral Immature Dendritic Cell Injections and Low-Dose Chemotherapies.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Therapeutic strategy for cancer immunotherapy in head and neck cancer2015

Author(s)

ISHII Hiroki 石井裕貴

Ishii Hiroki 石井裕貴

[Journal Article] スギ・ヒノキ花粉観測25年間の報告　山梨県における地域差と年次推移の検討2023