Tabata Keisuke 田端桂介

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田端桂介タバタケイスケ

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Researcher Number	40569018
Other IDs
Affiliation (Current)	2026: 順天堂大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2023 – 2025: 順天堂大学, 医学部, 准教授 2022: 大阪大学, 大学院生命機能研究科, 助教 2021: 大阪大学, 生命機能研究科, 助教 2013 – 2014: 大阪大学, 微生物病研究所, 特任助教(常勤)
Review Section/Research Field	Principal Investigator Basic Section 43030:Functional biochemistry-related / Basic Section 44010:Cell biology-related / Virology
Keywords	Principal Investigator オートファジー / リン酸化 / 相分離 / p62/SQSTM1 / 神経発達 / 翻訳後修飾 / プロテオーム / siRNAスクリーニング / 結合タンパク質 / エクソソーム … More / Rubicon変異体 / 神経発達障害 / Myoferlin / Rubicon / アルファウイルス / フラビウイルス Less

p62 body動態におけるリン酸化制御機構の解明Principal Investigator
- Principal Investigator
  
  田端桂介
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43030:Functional biochemistry-related
- Research Institution
  Juntendo University
Rubicon-mediated regulation of autophagy and its role in neurodevelopmentPrincipal Investigator
- Principal Investigator
  
  Tabata Keisuke
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 44010:Cell biology-related
- Research Institution
  Juntendo University
  Osaka University
プラス鎖RNAウイルス感染時におけるオートファジーの役割と分子基盤の解明Principal Investigator
- Principal Investigator
  
  田端桂介
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Virology
- Research Institution
  Osaka University

All 2024 2023 2022 2014 2013 Other

All Journal Article Presentation Book

[Book] 細胞の中から健康に保つ：オートファジーの分子機構と生理的な役割2023
- Author(s)
  田端　桂介
- Total Pages
  5
- Publisher
  北隆館　月刊「細胞」
- Data Source
  KAKENHI-PROJECT-21K06169
[Journal Article] Purification of hepatitis C virus core protein in non-denaturing condition2024
- Author(s)
  Izumida Kyo、Hara Yumiko、Furukawa Yukio、Ishida Kotaro、Tabata Keisuke、Morita Eiji
- Journal Title
  
  Journal of Virological Methods
  
  Volume: 323 Pages: 114852-114852
- DOI
  10.1016/j.jviromet.2023.114852
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K18378, KAKENHI-PROJECT-21K06169, KAKENHI-PROJECT-23K24135, KAKENHI-PROJECT-22H00553
[Journal Article] The Rubicon-WIPI axis regulates exosome biogenesis during ageing2024
- Author(s)
  Yanagawa K, Kuma A, Hamasaki M, Kita S, Yamamuro T, Nishino K, Nakamura S, Omori H, Kaminishi T, Oikawa S, Kato Y, Edahiro R, Kawagoe R, Taniguchi T, Tanaka Y, Shima T, Tabata K, Iwatani M, Bekku N, Hanayama R, Okada Y, Akimoto T, Kosako H, Takahashi A, Shimomura I, Sakata Y, Yoshimori T
- Journal Title
  
  Nature Cell Biology
  
  Volume: 26 Issue: 9 Pages: 1558-1570
- DOI
  10.1038/s41556-024-01481-0
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22H04982, KAKENHI-PROJECT-21K06169, KAKENHI-PROJECT-22K07222, KAKENHI-PROJECT-22K08669, KAKENHI-PROJECT-23K18140, KAKENHI-PROJECT-22KJ2105, KAKENHI-PROJECT-24K18072, KAKENHI-PROJECT-22KK0153
[Journal Article] Palmitoylation of ULK1 by ZDHHC13 plays a crucial role in autophagy2024
- Author(s)
  Tabata K, Imai K, Fukuda K, Yamamoto K, Kunugi H, Fujita T, Kaminishi T, Tischer C, Neumann B, Reither S, Verissimo F, Pepperkok R, Yoshimori T, Hamasaki M
- Journal Title
  
  Nature Communications
  
  Volume: 15 Issue: 1 Pages: 7194-7194
- DOI
  10.1038/s41467-024-51402-w
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22H04982, KAKENHI-PROJECT-21K06169
[Journal Article] Opposing roles of RUBCN isoforms in autophagy and memory B cell generation2023
- Author(s)
  Tsai Chao-Yuan、Sakakibara Shuhei、Kuan Yu-Diao、Omori Hiroko、El Hussien Maruwa Ali、Okuzaki Daisuke、Lu Shiou-Ling、Noda Takeshi、Tabata Keisuke、Nakamura Shuhei、Yoshimori Tamotsu、Kikutani Hitoshi
- Journal Title
  
  Science Signaling
  
  Volume: 16 Issue: 803 Pages: 1-15
- DOI
  10.1126/scisignal.ade3599
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06169, KAKENHI-PROJECT-20K15789, KAKENHI-PROJECT-22H04982, KAKENHI-PROJECT-23K27671
[Journal Article] Microautophagy regulated by <scp>STK38</scp> and <scp>GABARAPs</scp> is essential to repair lysosomes and prevent aging2023
- Author(s)
  Ogura Monami、Kaminishi Tatsuya、Shima Takayuki、Torigata Miku、Bekku Nao、Tabata Keisuke、Minami Satoshi、Nishino Kohei、Nezu Akiko、Hamasaki Maho、Kosako Hidetaka、Yoshimori Tamotsu、Nakamura Shuhei
- Journal Title
  
  EMBO reports
  
  Volume: 24 Issue: 12
- DOI
  10.15252/embr.202357300
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K18140, KAKENHI-PROJECT-22KJ2105, KAKENHI-PROJECT-21K06169, KAKENHI-PROJECT-21K06152, KAKENHI-PROJECT-22KJ2086, KAKENHI-ORGANIZER-21H05144, KAKENHI-PLANNED-21H05145, KAKENHI-PROJECT-22H04982, KAKENHI-PROJECT-21H02428
[Journal Article] Degradation of the NOTCH intracellular domain by elevated autophagy in osteoblasts promotes osteoblast differentiation and alleviates osteoporosis2022
- Author(s)
  Yoshida Gota、Kawabata Tsuyoshi、Takamatsu Hyota、Saita Shotaro、Nakamura Shuhei、Nishikawa Keizo、Fujiwara Mari、Enokidani Yusuke、Yamamuro Tadashi、Tabata Keisuke、Hamasaki Maho、Ishii Masaru、Kumanogoh Atsushi、Yoshimori Tamotsu
- Journal Title
  
  Autophagy
  
  Volume: - Issue: 10 Pages: 1-10
- DOI
  10.1080/15548627.2021.2017587
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22429, KAKENHI-PUBLICLY-20H05329, KAKENHI-PROJECT-21K06152, KAKENHI-PROJECT-21K06169, KAKENHI-PROJECT-23K24088
[Journal Article] Flavivirus recruits the valosin-containing protein?NPL4 complex to induce stress granule disassembly for efficient viral genome replication2022
- Author(s)
  Arakawa Masashi、Tabata Keisuke、Ishida Kotaro、Kobayashi Makiko、Arai Arisa、Ishikawa Tomohiro、Suzuki Ryosuke、Takeuchi Hiroaki、Tripathi Lokesh P.、Mizuguchi Kenji、Morita Eiji
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 298 Issue: 3 Pages: 101597-101597
- DOI
  10.1016/j.jbc.2022.101597
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21874, KAKENHI-PLANNED-17H06415, KAKENHI-PUBLICLY-20H05305, KAKENHI-PROJECT-21J12610, KAKENHI-PROJECT-21K06169
[Journal Article] How cells recognize and remove the perforated lysosome2022
- Author(s)
  Tabata Keisuke、Saeki Marika、Yoshimori Tamotsu、Hamasaki Maho
- Journal Title
  
  Autophagy
  
  Volume: - Issue: 6 Pages: 1-3
- DOI
  10.1080/15548627.2022.2138686
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06169, KAKENHI-PROJECT-22H04982, KAKENHI-PROJECT-21K06152
[Journal Article] Identification of CUL4A-DDB1-WDFY1 as an E3 ubiquitin ligase complex involved in initiation of lysophagy2022
- Author(s)
  Hirofumi Teranishi, Keisuke Tabata, Marika Saeki, Tetsuo Umemoto, Tomohisa Hatta, Takanobu Otomo, Kentaro Yamamoto, Toru Natsume, Tamotsu Yoshimori, Maho Hamasaki
- Journal Title
  
  Cell Reports
  
  Volume: 40(11) Issue: 11 Pages: 111349-111349
- DOI
  10.1016/j.celrep.2022.111349
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06152, KAKENHI-PROJECT-21K06169, KAKENHI-PROJECT-22H04982
[Journal Article] Structural Basis of the Autophagy-Related LC3/Atg13 LIR Complex: Recognition and Interaction Mechanism.2014
- Author(s)
  Hironori Suzuki, Keisuke Tabata, Eiji Morita, Masato Kawasaki, Ryuichi Kato, Renwick C J Dobson, Tamotsu Yoshimori, Soichi Wakatsuki
- Journal Title
  
  Structure
  
  Volume: 22 Pages: 47-58
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25860339
[Journal Article] Reciprocal conversion of Gtr1 and Gtr2 nucleotide-binding states by Npr2-Npr3 inactivates TORC1 and induces autophagy.2014
- Author(s)
  Shintaro Kira, Keisuke Tabata, Kanae Shirahama-Noda, Akiko Nozoe, Tamotsu Yoshimori and Takeshi Noda
- Journal Title
  
  Autophagy
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25860339
[Presentation] ULK1 palmitoylation by ZDHHC13 is required for autophagy2022
- Author(s)
  Tabata K.、 Yoshimori T.、Hamasaki M.
- Organizer
  Cold Spring Harbor Laboratory Meeting_ Mechanisms of Aging, 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06169
[Presentation] ZDHHC13はULK1をパルミトイル化することによりオートファジーを制御する2022
- Author(s)
  田端桂介、吉森保
- Organizer
  第74回日本細胞生物学会大会
- Data Source
  KAKENHI-PROJECT-21K06169
[Presentation] Involvement of ESCRT factors in Flavivirus propagation2014
- Author(s)
  Keisuke Tabata, Masaru Arimoto, Kazunobu Saito, Hiroko Omori, Yoshiharu Matsuura and Eiji Morita
- Organizer
  Keystone Symposia_The Ins and Outs of Viral Infection: Entry, Assembly, Exit and Spread (C6)
- Place of Presentation
  Colorado
- Data Source
  KAKENHI-PROJECT-25860339
[Presentation] フラビウイルス複製オルガネラ局在タンパク質のイメージング解析2014
- Author(s)
  田端桂介
- Organizer
  第21回　トガ・フラビ・ペスチウイルス研究会
- Place of Presentation
  横浜
- Year and Date
  2014-11-09
- Data Source
  KAKENHI-PROJECT-25860339
[Presentation] ESCRT factors are required for flavivirus propagation on endoplasmic reticulum2013
- Author(s)
  田端桂介、有本大、齊藤一伸、大森弘子、松浦善治、森田英嗣
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-25860339
[Presentation] フラビウイルスタンパク質と宿主因子の相互作用ネットワーク解析2013
- Author(s)
  田端桂介、有本大、Lokesh P. Tripathi、水口賢司、森田英嗣
- Organizer
  第20回トガ・フラビ・ペスチウイルス研究会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-25860339
[Presentation] Involvement of ESCRT factors in flavivirus replication2013
- Author(s)
  田端桂介、齊藤一伸、泉田響、有本大、原由美子、松浦善治、森田英嗣
- Organizer
  第65回日本細胞生物学会大会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-25860339
[Presentation] ESCRT factors are required for flavivirus propagation2013
- Author(s)
  田端桂介、有本大、齊藤一伸、大森弘子、松浦善治、森田英嗣
- Organizer
  第61回日本ウイルス学会学術集会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-25860339
[Presentation] Involvement of ESCRT factors in flavivirus replication2013
- Author(s)
  Keisuke Tabata, Masaru Arimoto, Kazunobu Saito, Hiroko Omori, Yoshiharu Matsuura and Eiji Morita
- Organizer
  Keystone Symposia_Positive Strand RNA Viruses (D7)
- Place of Presentation
  Boston
- Data Source
  KAKENHI-PROJECT-25860339
[Presentation] フラビウイルス増殖に関する新規宿主因子の探索及び同定
- Author(s)
  小林万希子、田端桂介、有本大、齊藤一伸、森田英嗣
- Organizer
  第62回日本ウイルス学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2014-11-10 – 2014-11-12
- Data Source
  KAKENHI-PROJECT-25860339

1. 中村修平

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
2. 森田英嗣

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
3. 吉森保

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
4. 濱崎万穂

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Tabata Keisuke 田端 桂介

田端 桂介 タバタ ケイスケ

Research Projects

Research Products

Co-Researchers

p62 body動態におけるリン酸化制御機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Rubicon-mediated regulation of autophagy and its role in neurodevelopmentPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

プラス鎖RNAウイルス感染時におけるオートファジーの役割と分子基盤の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 細胞の中から健康に保つ：オートファジーの分子機構と生理的な役割2023

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Purification of hepatitis C virus core protein in non-denaturing condition2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The Rubicon-WIPI axis regulates exosome biogenesis during ageing2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Palmitoylation of ULK1 by ZDHHC13 plays a crucial role in autophagy2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Opposing roles of RUBCN isoforms in autophagy and memory B cell generation2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Microautophagy regulated by <scp>STK38</scp> and <scp>GABARAPs</scp> is essential to repair lysosomes and prevent aging2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Degradation of the NOTCH intracellular domain by elevated autophagy in osteoblasts promotes osteoblast differentiation and alleviates osteoporosis2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Flavivirus recruits the valosin-containing protein?NPL4 complex to induce stress granule disassembly for efficient viral genome replication2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] How cells recognize and remove the perforated lysosome2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Identification of CUL4A-DDB1-WDFY1 as an E3 ubiquitin ligase complex involved in initiation of lysophagy2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Structural Basis of the Autophagy-Related LC3/Atg13 LIR Complex: Recognition and Interaction Mechanism.2014

Author(s)

Journal Title

Data Source

[Journal Article] Reciprocal conversion of Gtr1 and Gtr2 nucleotide-binding states by Npr2-Npr3 inactivates TORC1 and induces autophagy.2014

Author(s)

Journal Title

Tabata Keisuke 田端桂介

田端桂介タバタケイスケ