Johmura Yoshikazu 城村由和

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JOHMURA Yoshikazu 城村由和

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Researcher Number	40616322
Other IDs
Affiliation (Current)	2025: 金沢大学, がん進展制御研究所, 教授
Affiliation (based on the past Project Information) *help	2022 – 2025: 金沢大学, がん進展制御研究所, 教授 2016 – 2021: 東京大学, 医科学研究所, 助教 2014 – 2015: 名古屋市立大学, 医学(系)研究科(研究院), 助教
Review Section/Research Field	Principal Investigator Transformative Research Areas, Section (III) / Basic Section 49010:Pathological biochemistry-related / Medium-sized Section 49:Pathology, infection/immunology, and related fields / Medium-sized Section 48:Biomedical structure and function and related fields / Complex systems / Pathological medical chemistry / Tumor biology / General medical chemistry Except Principal Investigator Basic Section 59040:Nutrition science and health science-related / Medium-sized Section 46:Neuroscience and related fields
Keywords	Principal Investigator 細胞周期 / 老化 / 細胞老化 / がん / 個体老化 / 慢性炎症 / p16INK4A / 一細胞遺伝子発現解析 / 炎症 / 一細胞解析 … More / p53 / マルチオミクス / 多階層マルチオミクス / 部分的リプログラミング / 線維化 / 再生 / 加齢性疾患 / バイオイメージング / シングルセル解析 / 癌 / DNA損傷 / 神経細胞 / 神経変性疾患 / プロテオスタシス / 腎臓 / 脂肪肝 / 免疫チェックポイント / 生活習慣病 / 慢性腎不全 / 非アルコール性脂肪肝炎 / 生体イメージング / 細胞膜 / クリアランス / 免疫 / 脂質 / ゲノムワイド解析 / シグナル伝達 / ゲノムワイド / 代謝 … More Except Principal Investigator がん / 細胞老化 / 細胞間相互作用 / 神経疾患 / 脳老化 / 逆転写酵素阻害剤 / レトロトランスポゾン / レット症候群 / 老化 / 精神・神経疾患 Less

『一過性の老化細胞』と『慢性の老化細胞』の違いを生み出すメカニズムの解明Principal Investigator
- Principal Investigator
  
  城村由和
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 49:Pathology, infection/immunology, and related fields
- Research Institution
  Kanazawa University
Elucidation of the Aging Clock Revival Mechanism - A New Paradigm Shift in Aging ResearchArea Organizer
- Area Organizer
  
  城村由和
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (B)
老化時計リバイバル機構の解明 -老化研究における新たなパラダイムシフトの総括Principal Investigator
- Principal Investigator
  
  城村由和
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (B)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Kanazawa University
慢性炎症の起点となる細胞老化のリバイバル機構の解明Principal Investigator
- Principal Investigator
  
  城村由和
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (B)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Kanazawa University
Integrated understanding of cell-cell interaction mechanisms underlying brain dysfunction common to brain aging and neurological disorders
- Principal Investigator
  
  中島欽一
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 46:Neuroscience and related fields
- Research Institution
  Kyushu University
細胞種特異的な老化細胞制御システムを用いた個体老化・加齢性疾患病態機構の解明Principal Investigator
- Principal Investigator
  
  城村由和
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Kanazawa University
がん治療薬誘導性間質細胞老化の分子病態の解明と治療応用
- Principal Investigator
  
  坂本毅治
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Kansai Medical University
Constructing the denatured protein atlas map aimed at understanding individual aging and age-related diseasesPrincipal Investigator
- Principal Investigator
  
  Johmura Yoshikazu
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 48:Biomedical structure and function and related fields
- Research Institution
  Kanazawa University
包括的1細胞遺伝子発現解析による老化制御メカニズムの解明Principal Investigator
- Principal Investigator
  
  城村由和
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  The University of Tokyo
Elucidation of the regulatory mechanisms of cellular senescence using a novel mouse model to establish the molecular basis of agingPrincipal Investigator
- Principal Investigator
  
  Johmura Yoshikazu
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Kanazawa University
  The University of Tokyo
老化細胞が引き起こす慢性炎症機構の解明と予防法の確立Principal Investigator
- Principal Investigator
  
  城村由和
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Research Institution
  The University of Tokyo
Identification and functional analysis of regulators of senescencePrincipal Investigator
- Principal Investigator
  
  Johmura Yoshikazu
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Tumor biology
- Research Institution
  The University of Tokyo
Understanding of the mechansism for clearance of senescent cellsPrincipal Investigator
- Principal Investigator
  
  Johmura Yoshikazu
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Pathological medical chemistry
- Research Institution
  The University of Tokyo
Molecular characterization of cell fate determination in the DNA damage responsePrincipal Investigator
- Principal Investigator
  
  JOHMURA Yoshikazu
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Nagoya City University

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All Journal Article Presentation Book

[Book] 実験医学 41(15)2023
- Author(s)
  大森徳貴　城村由和
- Total Pages
  7
- Publisher
  羊土社
- ISBN
  9784758104135
- Data Source
  KAKENHI-PROJECT-23K27376
[Book] 実験医学 41(15)2023
- Author(s)
  大森徳貴　城村由和
- Total Pages
  7
- Publisher
  羊土社
- ISBN
  9784758104135
- Data Source
  KAKENHI-PLANNED-23H03835
[Book] 実験医学 41(15)2023
- Author(s)
  大森徳貴　城村由和
- Total Pages
  7
- Publisher
  羊土社
- ISBN
  9784758104135
- Data Source
  KAKENHI-PROJECT-22K19398
[Book] 実験医学 41(15)2023
- Author(s)
  大森徳貴　城村由和
- Total Pages
  7
- Publisher
  羊土社
- ISBN
  9784758104135
- Data Source
  KAKENHI-ORGANIZER-23H03834
[Book] . アンチ・エイジング医学2018
- Author(s)
  城村由和、中西真
- Total Pages
  7
- Publisher
  メディカルレビュー社
- ISBN
  9784779221606
- Data Source
  KAKENHI-PROJECT-16K15238
[Book] アンチ・エイジング医学2018
- Author(s)
  城村由和、中西真.
- Total Pages
  7
- Publisher
  メディカルレビュー社
- ISBN
  9784779221606
- Data Source
  KAKENHI-PUBLICLY-18H05026
[Book] アンチ・エイジング医学2018
- Author(s)
  城村由和、中西真.
- Total Pages
  7
- Publisher
  ディカルレビュー社
- ISBN
  9784779221606
- Data Source
  KAKENHI-PROJECT-16H06148
[Book] 実験医学2017
- Author(s)
  城村由和、中西真
- Total Pages
  6
- Publisher
  羊土社
- ISBN
  9784758101677
- Data Source
  KAKENHI-PROJECT-16K15238
[Book] 実験医学2017
- Author(s)
  城村由和、中西真
- Total Pages
  6
- Publisher
  羊土社
- ISBN
  9784758101677
- Data Source
  KAKENHI-PROJECT-16H06148
[Journal Article] Autophagy Inhibition?induced Cytosolic DNA Sensing Combined with Differentiation Therapy Induces Irreversible Myeloid Differentiation in Leukemia Cells2024
- Author(s)
  Baba Tomohisa、Tomaru Utano、Hirao Atsushi、Mukaida Naofumi、Johmura Yoshikazu
- Journal Title
  
  Cancer Research Communications
  
  Volume: 4 Issue: 3 Pages: 849-860
- DOI
  10.1158/2767-9764.crc-23-0507
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06966, KAKENHI-PROJECT-22K19398, KAKENHI-ORGANIZER-23H03834, KAKENHI-PLANNED-23H03835, KAKENHI-PROJECT-23K27376
[Journal Article] Plasma membrane damage limits replicative lifespan in yeast and induces premature senescence in human fibroblasts2024
- Author(s)
  Suda Kojiro、Moriyama Yohsuke、Razali Nurhanani、Chiu Yatzu、Masukagami Yumiko、Nishimura Koutarou、Barbee Hunter、Takase Hiroshi、Sugiyama Shinju、Yamazaki Yuta、Sato Yoshikatsu、Higashiyama Tetsuya、Johmura Yoshikazu、Nakanishi Makoto、Kono Keiko
- Journal Title
  
  Nature Aging
  
  Volume: 4 Issue: 3 Pages: 319-335
- DOI
  10.1038/s43587-024-00575-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22KJ3086, KAKENHI-PROJECT-22K19398, KAKENHI-PUBLICLY-22H04718, KAKENHI-PUBLICLY-23H04739, KAKENHI-ORGANIZER-23H03834, KAKENHI-PLANNED-23H03835, KAKENHI-PROJECT-20H03440, KAKENHI-PROJECT-23K26799, KAKENHI-PROJECT-23K27376
[Journal Article] LONRF2 is a protein quality control ubiquitin ligase whose deficiency causes late-onset neurological deficits2023
- Author(s)
  Li Dan、Johmura Yoshikazu、Morimoto Satoru et al.
- Journal Title
  
  Nature Aging
  
  Volume: 3 Issue: 8 Pages: 1001-1019
- DOI
  10.1038/s43587-023-00464-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K15736, KAKENHI-PROJECT-23K07345, KAKENHI-PROJECT-19K08267, KAKENHI-PROJECT-20K06464, KAKENHI-PROJECT-21K07411, KAKENHI-PROJECT-22K19398, KAKENHI-PROJECT-22K15724, KAKENHI-PROJECT-20H03162, KAKENHI-ORGANIZER-19H05739, KAKENHI-PLANNED-21H05278, KAKENHI-ORGANIZER-23H03834, KAKENHI-PLANNED-23H03835, KAKENHI-PROJECT-20H00485, KAKENHI-PROJECT-23K20328, KAKENHI-PROJECT-23K27084, KAKENHI-PROJECT-23K27376
[Journal Article] The chemotherapeutic drug doxorubicin does not exacerbate p16Ink4a-positive senescent cell accumulation and cardiometabolic disease development in young adult female LDLR-deficient mice2023
- Author(s)
  Postmus Andrea C.、Kruit Janine K.、Eilers Roos E.、Havinga Rick、Koster Mirjam H.、Johmura Yoshikazu、Nakanishi Makoto、van de Sluis Bart、Jonker Johan W.
- Journal Title
  
  Toxicology and Applied Pharmacology
  
  Volume: 468 Pages: 116531-116531
- DOI
  10.1016/j.taap.2023.116531
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19398, KAKENHI-ORGANIZER-23H03834, KAKENHI-PLANNED-23H03835, KAKENHI-PROJECT-23K27376
[Journal Article] In vivo dynamics of senescence in rhabdomyolysis-induced acute kidney injury2023
- Author(s)
  Harris Alexander S.、Aratani Sae、Johmura Yoshikazu、Suzuki Narumi、Dan Li、Nakanishi Makoto
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 673 Pages: 121-130
- DOI
  10.1016/j.bbrc.2023.06.046
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K19398, KAKENHI-ORGANIZER-19H05739, KAKENHI-ORGANIZER-23H03834, KAKENHI-PLANNED-23H03835, KAKENHI-PROJECT-23K27376
[Journal Article] Transcriptomic characterization of Lonrf1 at the single-cell level under pathophysiological conditions2023
- Author(s)
  Li Dan、Wang Teh-Wei、Aratani Sae、Omori Satotaka、Tamatani Maho、Johmura Yoshikazu、Nakanishi Makoto
- Journal Title
  
  The Journal of Biochemistry
  
  Volume: - Issue: 6 Pages: 459-469
- DOI
  10.1093/jb/mvad021
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K19398, KAKENHI-PROJECT-19H03431, KAKENHI-ORGANIZER-19H05739
[Journal Article] Targeting cellular senescence as a therapeutic approach in non-alcoholic steatohepatitis2023
- Author(s)
  Nakano Yasuhiro、Johmura Yoshikazu
- Journal Title
  
  Annals of Hepatology
  
  Volume: 28 Issue: 2 Pages: 100900-100900
- DOI
  10.1016/j.aohep.2023.100900
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03431
[Journal Article] Blocking PD-L1-PD-1 improves senescence surveillance and ageing phenotypes2022
- Author(s)
  Wang, T. W., Y. Johmura, N. Suzuki, S. Omori, T. Migita, K. Yamaguchi, S. Hatakeyama, S. Yamazaki, E. Shimizu, S. Imoto, Y. Furukawa, A. Yoshimura, and M. Nakanishi
- Journal Title
  
  Nature
  
  Volume: 611 Issue: 7935 Pages: 358-364
- DOI
  10.1038/s41586-022-05388-4
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19444, KAKENHI-PROJECT-21H05044, KAKENHI-PROJECT-19H03431, KAKENHI-PROJECT-20H03707, KAKENHI-PROJECT-20J21945, KAKENHI-PROJECT-21F21108, KAKENHI-PROJECT-20K07563, KAKENHI-ORGANIZER-19H05739
[Journal Article] Alteration of Trop-2 expression in breast cancer cells by clinically used therapeutic agents and acquired tamoxifen resistance2022
- Author(s)
  Zhu Jing、Wu Wenwen、Togashi Yukiko、Taira Nihira Naoe、Johmura Yoshikazu、Zhu Dajiang、Nakanishi Makoto、Miyoshi Yasuo、Ohta Tomohiko
- Journal Title
  
  Breast Cancer
  
  Volume: 29 Issue: 6 Pages: 1076-1087
- DOI
  10.1007/s12282-022-01389-3
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03431, KAKENHI-PROJECT-20H03748, KAKENHI-PROJECT-20J40010
[Journal Article] Sentinel p16INK4a+ cells in the basement membrane form a reparative niche in the lung2022
- Author(s)
  Reyes Nabora S.、Krasilnikov Maria、Allen Nancy C.、Lee Jin Young、Hyams Ben、Zhou Minqi、Ravishankar Supriya、Cassandras Monica、Wang Chaoqun、Khan Imran、Matatia Peri、Johmura Yoshikazu、Molofsky Ari、Matthay Michael、Nakanishi Makoto、Sheppard Dean、Campisi Judith、Peng Tien
- Journal Title
  
  Science
  
  Volume: 378 Issue: 6616 Pages: 192-201
- DOI
  10.1126/science.abf3326
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03431, KAKENHI-ORGANIZER-19H05739
[Journal Article] Senolysis by glutaminolysis inhibition ameliorates various age-associated disorders2021
- Author(s)
  Johmura Yoshikazu、Yamanaka Takehiro、Omori Satotaka、Wang Teh-Wei、Sugiura Yuki、Matsumoto Masaki、Suzuki Narumi、Kumamoto Soichiro、Yamaguchi Kiyoshi、Hatakeyama Seira、Takami Tomoyo、Yamaguchi Rui、Shimizu Eigo、Ikeda Kazutaka、Okahashi Nobuyuki、Mikawa Ryuta、Suematsu Makoto、Arita Makoto、Sugimoto Masataka et al
- Journal Title
  
  Science
  
  Volume: 371 Issue: 6526 Pages: 265-270
- DOI
  10.1126/science.abb5916
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07563, KAKENHI-PROJECT-20K21386, KAKENHI-PROJECT-20K21497, KAKENHI-PROJECT-18H05215, KAKENHI-ORGANIZER-17H06391, KAKENHI-PUBLICLY-19H04969, KAKENHI-PUBLICLY-19H05243, KAKENHI-ORGANIZER-19H05739, KAKENHI-PLANNED-19H05740, KAKENHI-PUBLICLY-20H04940, KAKENHI-PROJECT-19H03431, KAKENHI-PROJECT-20J13207, KAKENHI-PROJECT-20J21945, KAKENHI-PROJECT-16H06276, KAKENHI-PLANNED-20H05930, KAKENHI-PROJECT-20H00495, KAKENHI-PROJECT-20H04116
[Journal Article] TP53/p53-FBXO22-TFEB controls basal autophagy to govern hormesis2021
- Author(s)
  Suzuki Narumi、Johmura Yoshikazu、Wang Teh-Wei、Migita Toshiro、Wu Wenwen、Noguchi Rei、Yamaguchi Kiyoshi、Furukawa Yoichi、Nakamura Shuhei、Miyoshi Ichiro、Yoshimori Tamotsu、Ohta Tomohiko、Nakanishi Makoto
- Journal Title
  
  Autophagy
  
  Volume: 11 Issue: 11 Pages: 1-18
- DOI
  10.1080/15548627.2021.1897961
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22429, KAKENHI-PROJECT-20K21497, KAKENHI-ORGANIZER-17H06391, KAKENHI-ORGANIZER-19H05739, KAKENHI-PLANNED-19H05740, KAKENHI-PROJECT-20H03748, KAKENHI-PUBLICLY-20H04940, KAKENHI-PROJECT-19H03431, KAKENHI-PROJECT-20J13207, KAKENHI-PROJECT-20K07563
[Journal Article] Generation of a p16 Reporter Mouse and Its Use to Characterize and Target p16high Cells In Vivo.2020
- Author(s)
  Omori S, Wang TW, Johmura Y, ..., Sakamoto T (15番目), ..., Nakanishi M.
- Journal Title
  
  Cell Metab
  
  Volume: 32 Issue: 5 Pages: 814-828
- DOI
  10.1016/j.cmet.2020.09.006
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07659, KAKENHI-PROJECT-19K12215, KAKENHI-PROJECT-20K07563, KAKENHI-PROJECT-20K21497, KAKENHI-PROJECT-20K21612, KAKENHI-PROJECT-19KK0216, KAKENHI-PROJECT-17H06095, KAKENHI-PLANNED-17H06328, KAKENHI-ORGANIZER-17H06391, KAKENHI-PLANNED-17H06392, KAKENHI-ORGANIZER-19H05739, KAKENHI-PLANNED-19H05740, KAKENHI-PUBLICLY-20H04940, KAKENHI-PUBLICLY-20H05025, KAKENHI-PROJECT-20H00567, KAKENHI-PROJECT-19H03413, KAKENHI-PROJECT-19H03431, KAKENHI-PROJECT-20H03707, KAKENHI-PROJECT-19J01606, KAKENHI-PROJECT-20J21945, KAKENHI-PROJECT-17K07132, KAKENHI-PROJECT-18K15826, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-18K06024, KAKENHI-PROJECT-20H03162, KAKENHI-PROJECT-20H03474
[Journal Article] Cdk1-mediated DIAPH1 phosphorylation maintains metaphase cortical tension and inactivates the spindle assembly checkpoint at anaphase.2019
- Author(s)
  Nishimura K, Johmura Y, Deguchi K, Jiang Z, Uchida KSK, Suzuki N, Shimada M, Chiba Y, Hirota T, Yoshimura SH, Kono K, Nakanishi M.
- Journal Title
  
  Nature Communications
  
  Volume: 10 Issue: 1 Pages: 1-10
- DOI
  10.1038/s41467-019-08957-w
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H05026, KAKENHI-PROJECT-17H04045, KAKENHI-PROJECT-18H02681, KAKENHI-PROJECT-16H06148, KAKENHI-PROJECT-16J11221, KAKENHI-PROJECT-16K15238, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-18KK0196, KAKENHI-INTERNATIONAL-16K21723, KAKENHI-PLANNED-15H05977, KAKENHI-ORGANIZER-16H06429, KAKENHI-ORGANIZER-17H06391, KAKENHI-PUBLICLY-19H04830, KAKENHI-PROJECT-18H04034, KAKENHI-PROJECT-18H02436, KAKENHI-PROJECT-17H01398
[Journal Article] Isozyme-Specific Role of SAD-A in Neuronal Migration During Development of Cerebral Cortex2018
- Author(s)
  Nakanishi Keiko、Niida Hiroyuki、Tabata Hidenori、Ito Tsuyoshi、Hori Yuki、Hattori Madoka、Johmura Yoshikazu、Yamada Chisato、Ueda Takashi、Takeuchi Kosei、Yamada Kenichiro、Nagata Koh-ichi、Wakamatsu Nobuaki、Kishi Masashi、Pan Y Albert、Ugawa Shinya、Shimada Shoichi、Sanes Joshua R、Higashi Yujiro、Nakanishi Makoto
- Journal Title
  
  Cerebral Cortex
  
  Volume: 160 Issue: 9 Pages: 721-721
- DOI
  10.1093/cercor/bhy253
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07037, KAKENHI-PROJECT-16K08580, KAKENHI-ORGANIZER-17H06391, KAKENHI-PUBLICLY-18H05026, KAKENHI-PROJECT-16H06148, KAKENHI-PROJECT-16K15238, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-17K10949, KAKENHI-PROJECT-19K08267, KAKENHI-PROJECT-16K10119, KAKENHI-PLANNED-19H05740, KAKENHI-PROJECT-17H01398, KAKENHI-PUBLICLY-20H05483
[Journal Article] Fbxo22-mediated KDM4B degradation determines selective estrogen receptor modulator activity in breast cancer.2018
- Author(s)
  Johmura Y, Maeda I, Suzuki N, Wu W, Goda A,Morita M, Yamaguchi K, Yamamoto M, Nagasawa S, Kojima Y, Tsugawa K, Inoue N, Miyoshi Y, Osako T Akiyama F, Maruyama R, Inoue JI, Fukukawa Y, Ohta T, Nkanishi M.
- Journal Title
  
  J Clin Invest.
  
  Volume: 128 Issue: 12 Pages: 5603-5619
- DOI
  10.1172/jci121679
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08676, KAKENHI-PROJECT-18K15235, KAKENHI-PLANNED-16H06575, KAKENHI-ORGANIZER-17H06391, KAKENHI-PUBLICLY-18H05026, KAKENHI-PROJECT-17H03575, KAKENHI-PROJECT-17H03585, KAKENHI-PROJECT-16H06148, KAKENHI-PROJECT-16K15238, KAKENHI-PROJECT-17K18336, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-17H01398, KAKENHI-PROJECT-17K07214
[Journal Article] The G2 checkpoint inhibitor CBP-93872 increases the sensitivity of colorectal and pancreatic cancer cells to chemotherapy.2017
- Author(s)
  Iwata T, Uchino T, Koyama A, Johmura Y, Koyama K, Saito T, Ishiguro S, Arikawa T, Komatsu S, Miyachi M, Sano T, Nakanishi M, Shimada M.
- Journal Title
  
  Plos one
  
  Volume: 12 Issue: 5 Pages: 1-13
- DOI
  10.1371/journal.pone.0178221
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K15238, KAKENHI-PROJECT-16H06148, KAKENHI-PROJECT-15K08280, KAKENHI-PROJECT-16K15239, KAKENHI-PROJECT-17H01398
[Journal Article] Usp7-dependent histone H3 deubiquitylation regulates maintenance of DNA methylation.2017
- Author(s)
  Yamaguchi L, Nishiyama A, Misaki T, Johmura Y, Ueda J, Arita K, Nagao K, Obuse C, Nakanishi M
- Journal Title
  
  Scientific reports
  
  Volume: 7 Issue: 1 Pages: 1-12
- DOI
  10.1038/s41598-017-00136-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-15H01188, KAKENHI-PUBLICLY-15H01462, KAKENHI-PROJECT-16H04739, KAKENHI-PROJECT-16H04818, KAKENHI-PROJECT-16H06148, KAKENHI-PROJECT-14J07515, KAKENHI-PROJECT-26650002, KAKENHI-PROJECT-15K06942, KAKENHI-PROJECT-16K15238, KAKENHI-PROJECT-16K07099, KAKENHI-PLANNED-25116004, KAKENHI-PUBLICLY-16H01319, KAKENHI-PROJECT-26250027, KAKENHI-PROJECT-16K15239, KAKENHI-PROJECT-17H01398
[Journal Article] A combination of genetic and biochemical analyses for the diagnosis of PI3K-AKT-mTOR pathway-associated megalencephaly.2017
- Author(s)
  Negishi Y, Miya F, Hattori A, Johmura Y, Nakagawa M, Ando N, Hori I, Togawa T, Aoyama K, Ohashi K, Fukumura S, Mizuno S, Umemura A, Kishimoto Y, Okamoto N, Kato M, Tsunoda T, Yamasaki M, Kanemura Y, Kosaki K, Nakanishi M, Saitoh S.
- Journal Title
  
  BMC Med Genet.
  
  Volume: 18 Issue: 1 Pages: 4-4
- DOI
  10.1186/s12881-016-0363-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H06148, KAKENHI-PROJECT-16K07211, KAKENHI-PROJECT-16K15238, KAKENHI-PROJECT-16K15530, KAKENHI-PROJECT-26250027, KAKENHI-PROJECT-16K15239, KAKENHI-PROJECT-17H01398
[Journal Article] Defective DNA repair increases susceptibility to senescence through extension of Chk1-mediated G2 checkpoint activation.2016
- Author(s)
  Johmura Y, Yamashita E, Shimada M, Nakanishi K, Nakanishi M.
- Journal Title
  
  Sci Rep.
  
  Volume: - Issue: 1 Pages: 31194-31194
- DOI
  10.1038/srep31194
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06148, KAKENHI-PROJECT-25461659, KAKENHI-PROJECT-15K08280, KAKENHI-PROJECT-16K10119, KAKENHI-PROJECT-16K15238, KAKENHI-PROJECT-16K15239, KAKENHI-PROJECT-26250027
[Journal Article] Essential role of auto-activation circuitry on Aurora B-mediated H2AX-pS121 in mitosis2016
- Author(s)
  Shimada M, Goshima T, Matsuo H, Johmura Y, Murata K, Tanaka H, Ikawa M, Nakanishi K, and Nakanishi M.
- Journal Title
  
  Nature communications
  
  Volume: ８ Pages: 1-12
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26860195
[Journal Article] Multiple facets of p53 in senescence induction and maintenance.2016
- Author(s)
  Johmura Y, Nakanishi M.
- Journal Title
  
  Cancer Sci.
  
  Volume: 107 Issue: 11 Pages: 1550-1555
- DOI
  10.1111/cas.13060
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H06148, KAKENHI-PROJECT-16K15238, KAKENHI-PROJECT-16K15239, KAKENHI-PROJECT-26250027
[Journal Article] Structural and functional insights into IZUMO1 recognition by JUNO in mammalian fertilization.2016
- Author(s)
  Kato K, Satouh Y, Nishimasu H, Kurabayashi A, Morita J, Fujihara Y, Oji A, Ishitani R, Ikawa M, Nureki O.
- Journal Title
  
  Nat Commun.
  
  Volume: 7 Issue: 1 Pages: 12198-12198
- DOI
  10.1038/ncomms12059
- NAID
  120006957420
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-25112007, KAKENHI-PROJECT-25250014, KAKENHI-PROJECT-16H06148, KAKENHI-PROJECT-25461659, KAKENHI-PROJECT-15K08280, KAKENHI-PROJECT-16K10119, KAKENHI-PROJECT-16K11075, KAKENHI-PROJECT-16K15238, KAKENHI-PROJECT-16H06276, KAKENHI-ORGANIZER-25112001, KAKENHI-PROJECT-16K15239, KAKENHI-PROJECT-26250027
[Journal Article] HP1 regulates the localization of FANCJ at sites of DNA double-strand breaks.2016
- Author(s)
  Wu W, Togashi Y, Johmura Y, Miyoshi Y, Nobuoka S, Nakanishi M, Ohta T.
- Journal Title
  
  Cancer Sci.
  
  Volume: 107 Issue: 10 Pages: 1406-1415
- DOI
  10.1111/cas.13008
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-24112005, KAKENHI-PROJECT-16H06148, KAKENHI-PROJECT-26460402, KAKENHI-PROJECT-16K15238, KAKENHI-PROJECT-16K15712, KAKENHI-PROJECT-16K15239, KAKENHI-PROJECT-26290042, KAKENHI-PROJECT-26250027
[Journal Article] SCF(Fbxo22)-KDM4A targets methylated p53 for degradation and regulates senescence.2016
- Author(s)
  Johmura Y, Sun J, Kitagawa K, Nakanishi K, Kuno T, Naiki-Ito A, Sawada Y, Miyamoto T, Okabe A, Aburatani H, Li S-F, Miyoshi I, Takahashi S, Kitagawa M, Nakanishi M.
- Journal Title
  
  Nat. Commun.
  
  Volume: 7 Issue: 1 Pages: 10574-10574
- DOI
  10.1038/ncomms10574
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25461659, KAKENHI-PROJECT-24221011, KAKENHI-PROJECT-26250027, KAKENHI-PROJECT-26860195
[Journal Article] Loss of maintenance DNA methylation results in abnormal DNA origin firing during DNA replication2016
- Author(s)
  Haruta M, Shimada M, Nishiyama A, Johmura Y, Le Tallec B, Debatisse M, Nakanishi M
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 469 Issue: 4 Pages: 960-966
- DOI
  10.1016/j.bbrc.2015.12.090
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08280, KAKENHI-PUBLICLY-15H01188, KAKENHI-PROJECT-26250027, KAKENHI-PROJECT-26860195
[Journal Article] CBP-93872 inhibits NBS1-mediated ATR activation, abrogating maintenance of the DNA double-strand break-specific G2 checkpoint.2014
- Author(s)
  Hirokawa T, Shiotani B, Shimada M, Murata K, Johmura Y, Haruta M, Tahara H, Takeyama H, Nakanishi M.
- Journal Title
  
  Cancer Res.
  
  Volume: 74 Issue: 14 Pages: 3880-9
- DOI
  10.1158/0008-5472.can-13-3604
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-22118003, KAKENHI-PUBLICLY-25112711, KAKENHI-PROJECT-25293290, KAKENHI-PROJECT-25701005, KAKENHI-PROJECT-26250027, KAKENHI-PROJECT-26290047, KAKENHI-PROJECT-26310106, KAKENHI-PROJECT-26640091, KAKENHI-PROJECT-26860195, KAKENHI-PROJECT-221S0001
[Journal Article] Necessary and sufficient role for a mitosis skip in senescence induction.2014
- Author(s)
  Johmura Y, Shimada M, Misaki T, Naiki-Ito A, Miyoshi H, Motoyama N, Ohtani N, Hara E, Nakamura M, Morita A, Takahashi S, Nakanishi M.
- Journal Title
  
  Mol.Cell
  
  Volume: 55 Issue: 1 Pages: 73-84
- DOI
  10.1016/j.molcel.2014.05.003
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22118003, KAKENHI-PLANNED-23112101, KAKENHI-PROJECT-24590369, KAKENHI-PROJECT-24650625, KAKENHI-PROJECT-26250027, KAKENHI-PROJECT-26250028, KAKENHI-PROJECT-26860195
[Presentation] 細胞老化を標的とした先進的な健康寿命延伸法の創出を目指して2023
- Author(s)
  城村由和
- Organizer
  第82回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PLANNED-23H03835
[Presentation] 変性タンパク質選択的ユビキチンリガーゼLONRF2の欠損は加齢性神経変性を引き起こす2023
- Author(s)
  城村由和
- Organizer
  第23回日本抗加齢医学会総会
- Invited
- Data Source
  KAKENHI-PLANNED-23H03835
[Presentation] ユビキチンリガーゼLONRF2による変性タンパク質分解を介したプロテオスタシス制御2023
- Author(s)
  城村由和
- Organizer
  第75回日本細胞生物学会シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-22K19398
[Presentation] ユビキチンリガーゼLONRF2による変性タンパク質分解を介したプロテオスタシス制御2023
- Author(s)
  城村由和
- Organizer
  第75回日本細胞生物学会シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-23K27376
[Presentation] Analysis of the dynamics, origin, and properties of senescent cells induced during tissue damage2023
- Author(s)
  Nakano Y, Johmura Y
- Organizer
  第96回日本生化学会大会
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K27376
[Presentation] In Vivo Lineage Tracing of p16-expressing Senescent Cells in Acute Liver Injury2023
- Author(s)
  Nakano Y, Zhang Z, Kumamoto S, Johmura Y
- Organizer
  第18回生命医科学研究所ネットワーク国際シンポジウム
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19398
[Presentation] Developing the approaches to treat aging and chronic inflammatory diseases by targeting senescent cells2023
- Author(s)
  Johmura Y
- Organizer
  India - Japan Cancer Symposium International Symposium on Tumor Biology in Kanazawa 2023 Kanazawa University SAKIGAKE Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K27376
[Presentation] 老化細胞の一細胞遺伝子発現解析による加齢に伴うがんの悪性進展機構の解明2023
- Author(s)
  城村由和
- Organizer
  第10回JCRベーシックリサーチカンファレンス
- Invited
- Data Source
  KAKENHI-PROJECT-23K27376
[Presentation] 細胞老化を標的とした先進的な健康寿命延伸法の創出を目指して2023
- Author(s)
  城村由和
- Organizer
  第82回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-22K19398
[Presentation] Pre-existed Senescent Fibroblasts in aged bladder create tumor permissive niche2023
- Author(s)
  Johmura Y
- Organizer
  The 11th KUCRI-FUSCC Joint Symposium on Tumor Biology 2023
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-23H03834
[Presentation] Developing the approaches to treat aging and chronic inflammatory diseases by targeting senescent cells2023
- Author(s)
  Johmura Y
- Organizer
  India - Japan Cancer Symposium International Symposium on Tumor Biology in Kanazawa 2023 Kanazawa University SAKIGAKE Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-23H03834
[Presentation] In Vivo Lineage Tracing of p16-expressing Senescent Cells in Acute Liver Injury2023
- Author(s)
  Nakano Y, Zhang Z, Kumamoto S, Johmura Y
- Organizer
  第18回生命医科学研究所ネットワーク国際シンポジウム
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-23H03834
[Presentation] Autophagy inhibitors cooperate to induce an irreversible myeloid differentiation in AML differentiation therapy2023
- Author(s)
  Baba T, Johmura Y
- Organizer
  第82回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-22K19398
[Presentation] 老化細胞の一細胞遺伝子発現解析による加齢に伴うがんの悪性進展機構の解明2023
- Author(s)
  城村由和
- Organizer
  第10回JCRベーシックリサーチカンファレンス
- Invited
- Data Source
  KAKENHI-ORGANIZER-23H03834
[Presentation] 変性タンパク質選択的ユビキチンリガーゼLONRF2の欠損は加齢性神経変性を引き起こす2023
- Author(s)
  城村由和
- Organizer
  第23回日本抗加齢医学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-23K27376
[Presentation] 老化細胞の一細胞遺伝子発現解析による加齢に伴うがんの悪性進展機構の解明2023
- Author(s)
  城村由和
- Organizer
  第10回JCRベーシックリサーチカンファレンス
- Invited
- Data Source
  KAKENHI-PLANNED-23H03835
[Presentation] Analysis of the dynamics, origin, and properties of senescent cells induced during tissue damage2023
- Author(s)
  Nakano Y, Johmura Y
- Organizer
  第96回日本生化学会大会
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-23H03834
[Presentation] 老化細胞の一細胞遺伝子発現解析による加齢に伴うがんの悪性進展機構の解明2023
- Author(s)
  城村由和
- Organizer
  第10回JCRベーシックリサーチカンファレンス
- Invited
- Data Source
  KAKENHI-PROJECT-22K19398
[Presentation] がん間質中の老化細胞の同定と性状解析2023
- Author(s)
  城村由和
- Organizer
  第97回日本薬理学会年会
- Invited
- Data Source
  KAKENHI-ORGANIZER-23H03834
[Presentation] Developing the approaches to treat aging and chronic inflammatory diseases by targeting senescent cells2023
- Author(s)
  Johmura Y
- Organizer
  India - Japan Cancer Symposium International Symposium on Tumor Biology in Kanazawa 2023 Kanazawa University SAKIGAKE Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-23H03835
[Presentation] Analysis of the dynamics, origin, and properties of senescent cells induced during tissue damage2023
- Author(s)
  Nakano Y, Johmura Y
- Organizer
  第96回日本生化学会大会
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19398
[Presentation] がん間質中の老化細胞の同定と性状解析2023
- Author(s)
  城村由和
- Organizer
  第97回日本薬理学会年会
- Invited
- Data Source
  KAKENHI-PLANNED-23H03835
[Presentation] Autophagy inhibitors cooperate to induce an irreversible myeloid differentiation in AML differentiation therapy2023
- Author(s)
  Baba T, Johmura Y
- Organizer
  第82回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PLANNED-23H03835
[Presentation] がん間質中の老化細胞の同定と性状解析2023
- Author(s)
  城村由和
- Organizer
  第97回日本薬理学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-22K19398
[Presentation] In Vivo Lineage Tracing of p16-expressing Senescent Cells in Acute Liver Injury2023
- Author(s)
  Nakano Y, Zhang Z, Kumamoto S, Johmura Y
- Organizer
  第18回生命医科学研究所ネットワーク国際シンポジウム
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-23H03835
[Presentation] In Vivo Lineage Tracing of p16-expressing Senescent Cells in Acute Liver Injury2023
- Author(s)
  Nakano Y, Zhang Z, Kumamoto S, Johmura Y
- Organizer
  第18回生命医科学研究所ネットワーク国際シンポジウム
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K27376
[Presentation] Autophagy inhibitors cooperate to induce an irreversible myeloid differentiation in AML differentiation therapy2023
- Author(s)
  Baba T, Johmura Y
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-23K27376
[Presentation] Pre-existed Senescent Fibroblasts in aged bladder create tumor permissive niche2023
- Author(s)
  Johmura Y
- Organizer
  The 11th KUCRI-FUSCC Joint Symposium on Tumor Biology 2023
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-23H03835
[Presentation] Autophagy inhibitors cooperate to induce an irreversible myeloid differentiation in AML differentiation therapy2023
- Author(s)
  Baba T, Johmura Y
- Organizer
  第82回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-ORGANIZER-23H03834
[Presentation] ユビキチンリガーゼLONRF2による変性タンパク質分解を介したプロテオスタシス制御2023
- Author(s)
  城村由和
- Organizer
  第75回日本細胞生物学会シンポジウム
- Invited
- Data Source
  KAKENHI-ORGANIZER-23H03834
[Presentation] Developing the approaches to treat aging and chronic inflammatory diseases by targeting senescent cells2023
- Author(s)
  Johmura Y
- Organizer
  India - Japan Cancer Symposium International Symposium on Tumor Biology in Kanazawa 2023 Kanazawa University SAKIGAKE Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19398
[Presentation] Pre-existed Senescent Fibroblasts in aged bladder create tumor permissive niche2023
- Author(s)
  Johmura Y
- Organizer
  The 11th KUCRI-FUSCC Joint Symposium on Tumor Biology 2023
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K27376
[Presentation] 細胞老化を標的とした先進的な健康寿命延伸法の創出を目指して2023
- Author(s)
  城村由和
- Organizer
  第82回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-23K27376
[Presentation] がん間質中の老化細胞の同定と性状解析2023
- Author(s)
  城村由和
- Organizer
  第97回日本薬理学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-23K27376
[Presentation] ユビキチンリガーゼLONRF2による変性タンパク質分解を介したプロテオスタシス制御2023
- Author(s)
  城村由和
- Organizer
  第75回日本細胞生物学会シンポジウム
- Invited
- Data Source
  KAKENHI-PLANNED-23H03835
[Presentation] Analysis of the dynamics, origin, and properties of senescent cells induced during tissue damage2023
- Author(s)
  Nakano Y, Johmura Y
- Organizer
  第96回日本生化学会大会
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-23H03835
[Presentation] Pre-existed Senescent Fibroblasts in aged bladder create tumor permissive niche2023
- Author(s)
  Johmura Y
- Organizer
  The 11th KUCRI-FUSCC Joint Symposium on Tumor Biology 2023
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19398
[Presentation] 変性タンパク質選択的ユビキチンリガーゼLONRF2の欠損は加齢性神経変性を引き起こす2023
- Author(s)
  城村由和
- Organizer
  第23回日本抗加齢医学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-22K19398
[Presentation] 細胞老化を標的とした先進的な健康寿命延伸法の創出を目指して2023
- Author(s)
  城村由和
- Organizer
  第82回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-ORGANIZER-23H03834
[Presentation] 変性タンパク質選択的ユビキチンリガーゼLONRF2の欠損は加齢性神経変性を引き起こす2023
- Author(s)
  城村由和
- Organizer
  第23回日本抗加齢医学会総会
- Invited
- Data Source
  KAKENHI-ORGANIZER-23H03834
[Presentation] リソソーム恒常性維持の破綻による老化細胞形質の獲得メカニズム2022
- Author(s)
  城村由和
- Organizer
  第95回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03431
[Presentation] 老化細胞の免疫監視機構の解明による新たな個体老化制御法の可能性2022
- Author(s)
  城村由和
- Organizer
  第32回日本サイトメトリー学会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03431
[Presentation] Targeting immune escape mechanism in senescent cells ameliorates various senescence-associated disorders2022
- Author(s)
  Yoshikazu Johmura
- Organizer
  23rd Northeastern Asian Symposium on “Cellular Senescence: From Pathophysiology to Treatment
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03431
[Presentation] Escape from senescence surveillance by PD-L1-PD-1 immune checkpoint and its blockade ameliorates various senescence-associated disorders2022
- Author(s)
  Yoshikazu Johmura
- Organizer
  2nd Chinese Oncology Young Elite Summit 2022
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03431
[Presentation] 一細胞解析を用いたがんにおける細胞老化の多様性と役割の解明2021
- Author(s)
  城村由和
- Organizer
  第80回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PUBLICLY-20H04940
[Presentation] 免疫チェックポイント阻害による老化細胞除去と個体老化制御2021
- Author(s)
  王徳偉、城村由和、中西真
- Organizer
  第94回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PUBLICLY-20H04940
[Presentation] 免疫チェックポイント阻害による老化細胞除去と個体老化制御2021
- Author(s)
  王徳偉、城村由和、中西真
- Organizer
  第94回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03431
[Presentation] 老化細胞の生存維持に重要な代謝特性の理解とそれを標的とした新たな個体老化制御法の開発2021
- Author(s)
  城村由和
- Organizer
  第63回日本老年医学会学術集会
- Invited
- Data Source
  KAKENHI-PUBLICLY-20H04940
[Presentation] 老化細胞の生存維持に重要な代謝特性の理解とそれを標的とした新たな個体老化制御法の開発2021
- Author(s)
  城村由和
- Organizer
  第63回日本老年医学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03431
[Presentation] 一細胞解析を用いたがんにおける細胞老化の多様性と役割の解明2021
- Author(s)
  城村由和
- Organizer
  第80回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03431
[Presentation] Tissue and cell type-specific heterogeneity of p16high senescent cells revealed by single-cell transcriptomes2020
- Author(s)
  城村由和
- Organizer
  MBSJ2020
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-20H04940
[Presentation] Tissue and cell type-specific heterogeneity of p16high senescent cells revealed by single-cell transcriptomes2020
- Author(s)
  城村由和
- Organizer
  MBSJ2020
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03431
[Presentation] Challenging boundaries in healthspan: Mechanisms of cellular senescence induction and maintenance2019
- Author(s)
  Yoshikazu Johmura
- Organizer
  6th Symposium of the Smart-Aging Research Center
- Invited
- Data Source
  KAKENHI-PROJECT-16H06148
[Presentation] Role of cellular senescence in aging and age-related disorders2019
- Author(s)
  Yoshikazu Johmura
- Organizer
  1st International Symposium on Inflammation Cellular Sociology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H05026
[Presentation] Challenging boundaries in healthspan: Mechanisms of cellular senescence induction and maintenance2019
- Author(s)
  Yoshikazu Johmura
- Organizer
  6th Symposium of the Smart-Aging Research Center
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H05026
[Presentation] Role of cellular senescence in aging and age-related disorder2019
- Author(s)
  Yoshikazu Johmura
- Organizer
  1st International Symposium on Inflammation Cellular Sociology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03431
[Presentation] Challenging boundaries in healthspan: Mechanisms of cellular senescence induction and maintenance2019
- Author(s)
  Yoshikazu Johmura
- Organizer
  6th Symposium of the Smart-Aging Research Center
- Invited
- Data Source
  KAKENHI-PROJECT-16K15238
[Presentation] SCFfbxo22-KDM4A targets methylated p53 for degradation2016
- Author(s)
  Yoshikazu Johmura, Jia Sun, and Makoto Nakanishi
- Organizer
  Kick-Off Symposium in Nagoya City University 2016
- Place of Presentation
  名古屋市立大学（愛知県名古屋市）
- Year and Date
  2016-02-29
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860195
[Presentation] 細胞老化の誘導機構と発がん・個体老化における役割2015
- Author(s)
  城村由和
- Organizer
  東京大学医科学研究所共同研究拠点. 平成 27 年度若手研究者シンポジウム. 若手研究者が拓く医科学研究の道
- Place of Presentation
  東京大学医科学研究所（東京都港区）
- Year and Date
  2015-12-15
- Invited
- Data Source
  KAKENHI-PROJECT-26860195
[Presentation] Molecular characterization of cell fate determination in the DNA damage response
- Author(s)
  Y. Johmura, E. Yamashita, M. Nakanishi
- Organizer
  9th 3R meeting
- Place of Presentation
  静岡県・御殿場
- Year and Date
  2014-11-17 – 2014-11-21
- Data Source
  KAKENHI-PROJECT-26860195

1. 木戸丈友 (00401034)

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2. 矢木宏和 (70565423)

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3. 菱田友昭 (80521062)

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4. 中島欽一 (80302892)

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5. 坂本毅治 (70511418)

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6. 田中伯享 (30815882)

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7. BABA Tomohisa

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8. YAMAGUCHI Kiyoshi

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9. SATOUH Yuhkoh

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10. FUJIHARA Yoshitaka

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11. ITO MIHARU

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12. WU Wenwen

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13. SHIMADA Midori

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14. 吉村昭彦

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15. 向田直史

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16. 中西真

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17. 森本悟

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18. 田畑秀典

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19. 伊川正人

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20. 太田智彦

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21. 中村修平

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22. 中西圭子

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23. 西山敦哉

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Johmura Yoshikazu 城村 由和

JOHMURA Yoshikazu 城村 由和

Research Projects

Research Products

Co-Researchers

『一過性の老化細胞』と『慢性の老化細胞』の違いを生み出すメカニズムの解明Principal Investigator

Principal Investigator

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Elucidation of the Aging Clock Revival Mechanism - A New Paradigm Shift in Aging ResearchArea Organizer

Area Organizer

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老化時計リバイバル機構の解明 -老化研究における新たなパラダイムシフトの総括Principal Investigator

Principal Investigator

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慢性炎症の起点となる細胞老化のリバイバル機構の解明Principal Investigator

Principal Investigator

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Review Section

Research Institution

Integrated understanding of cell-cell interaction mechanisms underlying brain dysfunction common to brain aging and neurological disorders

Principal Investigator

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細胞種特異的な老化細胞制御システムを用いた個体老化・加齢性疾患病態機構の解明Principal Investigator

Principal Investigator

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がん治療薬誘導性間質細胞老化の分子病態の解明と治療応用

Principal Investigator

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Constructing the denatured protein atlas map aimed at understanding individual aging and age-related diseasesPrincipal Investigator

Principal Investigator

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包括的1細胞遺伝子発現解析による老化制御メカニズムの解明Principal Investigator

Principal Investigator

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Elucidation of the regulatory mechanisms of cellular senescence using a novel mouse model to establish the molecular basis of agingPrincipal Investigator

Principal Investigator

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老化細胞が引き起こす慢性炎症機構の解明と予防法の確立Principal Investigator

Principal Investigator

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Identification and functional analysis of regulators of senescencePrincipal Investigator

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Understanding of the mechansism for clearance of senescent cellsPrincipal Investigator

Principal Investigator

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Johmura Yoshikazu 城村由和

JOHMURA Yoshikazu 城村由和