Kikushige Yoshikane 菊繁吉謙

Researcher Number	40619706
Affiliation (Current)	2025: 九州大学, 大学病院, 講師
Affiliation (based on the past Project Information) *help	2020 – 2025: 九州大学, 大学病院, 講師 2019 – 2020: 九州大学, 医学研究院, 講師 2018: 九州大学, 医学研究院, 助教 2017: 九州大学, 大学病院, 助教 2016: 九州大学, 医学研究院, 助教 2015 – 2016: 九州大学, 医学(系)研究科(研究院), 助教 2014: 九州大学, 医学(系)研究科(研究院), 研究員
Review Section/Research Field	Principal Investigator Basic Section 54010:Hematology and medical oncology-related / Hematology / Medium-sized Section 54:Internal medicine of the bio-information integration and related fields Except Principal Investigator Basic Section 54010:Hematology and medical oncology-related / Hematology / Medium-sized Section 54:Internal medicine of the bio-information integration and related fields / Basic Section 50010:Tumor biology-related
Keywords	Principal Investigator 白血病幹細胞 / TIM-3 / ミトコンドリア / OXPHOS / アロマターゼ / thrombosis / IMiDs / アミノ酸代謝 / 代謝 / がん代謝 … More / 癌 / TIM-3分子 / Want pathway / LSCs / AML / β-catenin / galectin-9 / がん幹細胞 / 急性骨髄性白血病 … More Except Principal Investigator 白血病幹細胞 / 急性骨髄性白血病 / TIM-3 / 治療抵抗性 / 白血病 / AML / エピゲノム / 代謝 / 微小残存病変 / SPHK1/2阻害剤 / S1PR1 / 急性白血病 / PML-RARA / 急性前骨髄球性白血病 / PML::RARA / APL / 炎症性サイトカイン / 上皮再生 / 腸幹細胞 / STAT1 / MYC / IFN-gamma / 腸管オルガノイド / 同種造血幹細胞移植 / GVHD / DNAシークエンス / がん微小環境 / がん免疫 / 腫瘍免疫 / 大腸がん / クローン性造血 / 白血病発症 / 概日リズム遺伝子 / MLL融合タンパク / クロマチン修飾因子 / リジンアセチル化酵素 / クロマチン修飾酵素 / 概日リズム因子 / ゲノム編集 / プレmRNAプロセッシング / 分化誘導療法 / CRISPR/Cas9 / CRISPR/Cas9スクリーニング / PAICS / DCPS / CRISPR / T-ALL / T細胞性腫瘍 / β-catenin / Wnt pathway / 癌微小環境 / 血液学 / 幹細胞 / 微小環境 / がん幹細胞 / 自己複製能力 / 骨髄系腫瘍 / シグナル / アミノ酸代謝 / メタボローム / メタボロミクス / 治療抵抗性残存白血病 Less

Functional analysis of treatment-resistant leukemia stem cells and identification of molecular targets
- Principal Investigator
  
  宮本敏浩
- Project Period (FY)
  2025 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Kanazawa University
Elucidation of ribosome biogenesis in leukemic stem cells and the establishment of a novel therapeutic application
- Principal Investigator
  
  赤司浩一
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 54:Internal medicine of the bio-information integration and related fields
- Research Institution
  Kyushu University
白血病幹細胞の薬剤耐性機構の解明
- Principal Investigator
  
  小田原淳
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Kyushu University
炎症性サイトカインによる腸管上皮細胞の再生誘導の解析
- Principal Investigator
  
  高嶋秀一郎
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  National Hospital Organization, Kyushu Medical Center (Clinical Institute)
PML-RARA of the short but long isoform initiate from TIM-3+ leukemic stem cells with hierarchical leukemic organization
- Principal Investigator
  
  Miyamoto Toshihiro
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 54:Internal medicine of the bio-information integration and related fields
- Research Institution
  Kanazawa University
Elucidation of leukemic stem cell-specific mitochondrial activation mechanisms and establishment of novel therapeutic approach against AMLPrincipal Investigator
- Principal Investigator
  
  菊繁吉謙
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Kyushu University
lucidation of molecular function of TIM-3 in human leukemic stem cells
- Principal Investigator
  
  Akashi Koichi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 54:Internal medicine of the bio-information integration and related fields
- Research Institution
  Kyushu University
Characterization of immune responses in tumor microenvironment of patients with clonal hematopoiesis
- Principal Investigator
  
  Isobe Taichi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Kyushu University
Targeting minimal residual leukemic stem cells
- Principal Investigator
  
  Miyamoto Toshihiro
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Kanazawa University
Establishment of novel therapeutic strategies against cancers via identification of neosubstrate of IMiDsPrincipal Investigator
- Principal Investigator
  
  Kikushige Yoshikane
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 54:Internal medicine of the bio-information integration and related fields
- Research Institution
  Kyushu University
Identification of human acute leukemia specific metabolic pathwaysPrincipal Investigator
- Principal Investigator
  
  Kikushige Yoshikane
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Kyushu University
Targeting circadian clock genes in leukemia treatment
- Principal Investigator
  
  Numata Akihiko
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Kyushu University
Identification of novel targets for leukemia therapy using genome-wide CRISPR/Cas9 screens
- Principal Investigator
  
  Takahiro Maeda
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Hematology
- Research Institution
  Kyushu University
Elucidation of molecular machineries for the regulation of myeloid leukemia stem cells
- Principal Investigator
  
  AKASHI KOICHI
- Project Period (FY)
  2016 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Hematology
- Research Institution
  Kyushu University
ヒト骨髄性白血病における「静と動」の幹細胞維持・進展メカニズム
- Principal Investigator
  
  赤司浩一
- Project Period (FY)
  2016
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Hematology
- Research Institution
  Kyushu University
Elucidation of TIM-3 signaling patwhay involved in leukemic stem cells
- Principal Investigator
  
  Miyamoto Toshihiro
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  Kyushu University
Elucidation of the function of exhaustion-related molecules in human leukemic stem cellsPrincipal Investigator
- Principal Investigator
  
  Kikushige Yoshikane
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Hematology
- Research Institution
  Kyushu University
Identification of the novel therapeutic target molecules for leukemia stem cells based on TIM-3/galectin-9 interactionPrincipal Investigator
- Principal Investigator
  
  Kikushige Yoshikane
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Hematology
- Research Institution
  Kyushu University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014

All Journal Article Presentation

[Journal Article] Autologous <scp>HSCT</scp> with novel agent‐based induction and consolidation followed by lenalidomide maintenance for untreated multiple myeloma2024
- Author(s)
  Mori Yasuo、Takizawa Jun、Katsuoka Yuna、Takezako Naoki、Nagafuji Koji、Handa Hiroshi、Kuroda Junya、Sunami Kazutaka、Kamimura Tomohiko、Ogawa Ryosuke、Kikushige Yoshikane、Harada Mine、Akashi Koichi、Miyamoto Toshihiro、The Japan Study Group for Cell Therapy and Transplantation
- Journal Title
  
  Cancer Science
  
  Volume: - Issue: 6 Pages: 2002-2011
- DOI
  10.1111/cas.16158
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H04827
[Journal Article] Prognostic impact of HLA supertype mismatch in single-unit cord blood transplantation2024
- Author(s)
  Sugio T, Uchida N, Miyawaki K, Ohno Y, Eto T, Mori Y, Yoshimoto G, Kikushige Y, Kunisaki Y, Mizuno S, Nagafuji K, Iwasaki H, Kamimura T, Ogawa R, Miyamoto T, Taniguchi S, Akashi K, Kato K.
- Journal Title
  
  Bone Marrow Transplant
  
  Volume: 59 Issue: 4 Pages: 466-472
- DOI
  10.1038/s41409-023-02183-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07153, KAKENHI-PROJECT-21H04827, KAKENHI-PROJECT-23K24364
[Journal Article] Thrombospondin-1 is an endogenous substrate of cereblon responsible for immunomodulatory drug?induced thromboembolism2024
- Author(s)
  Hatakeyama Kiwamu、Kikushige Yoshikane、Ishihara Daisuke、Yamamoto Shunsuke、Kawano Gentaro、Tochigi Taro、Miyamoto Toshihiro、Sakoda Teppei、Christoforou Andy、Kunisaki Yuya、Fukata Mitsuhiro、Kato Koji、Ito Takumi、Handa Hiroshi、Akashi Koichi
- Journal Title
  
  Blood Advances
  
  Volume: 8 Issue: 3 Pages: 785-796
- DOI
  10.1182/bloodadvances.2023010080
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04827, KAKENHI-PROJECT-21H02950, KAKENHI-PROJECT-23K24364
[Journal Article] POT1a deficiency in mesenchymal niches perturbs B-lymphopoiesis2023
- Author(s)
  Nakashima Kentaro、Kunisaki Yuya、Hosokawa Kentaro、Gotoh Kazuhito、Yao Hisayuki、Yuta Ryosuke、Semba Yuichiro、Nogami Jumpei、Kikushige Yoshikane、Stumpf Patrick S.、MacArthur Ben D.、Kang Dongchon、Akashi Koichi、Ohga Shouichi、Arai Fumio
- Journal Title
  
  Communications Biology
  
  Volume: 6 Issue: 1 Pages: 1-14
- DOI
  10.1038/s42003-023-05374-0
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K18301, KAKENHI-PROJECT-23K07861, KAKENHI-PROJECT-21H04827, KAKENHI-PROJECT-21H02950, KAKENHI-PROJECT-23K24364, KAKENHI-PROJECT-23K27626
[Journal Article] <scp>GPAM</scp> mediated lysophosphatidic acid synthesis regulates mitochondrial dynamics in acute myeloid leukemia2023
- Author(s)
  Irifune Hidetoshi、Kochi Yu、Miyamoto Toshihiro、Sakoda Teppei、Kato Koji、Kunisaki Yuya、Akashi Koichi、Kikushige Yoshikane
- Journal Title
  
  Cancer Science
  
  Volume: 114 Issue: 8 Pages: 3247-3258
- DOI
  10.1111/cas.15835
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H04827, KAKENHI-PROJECT-21H02950, KAKENHI-PROJECT-21H02951, KAKENHI-PROJECT-23K24364
[Journal Article] Peripheral helper-T-cell-derived CXCL13 is a crucial pathogenic factor in idiopathic multicentric Castleman disease2023
- Author(s)
  Harada Takuya、Kikushige Yoshikane、Miyamoto Toshihiro、Uno Kazuko、Niiro Hiroaki、Kawakami Atsushi、Koga Tomohiro、Akashi Koichi、Yoshizaki Kazuyuki
- Journal Title
  
  Nature Communications
  
  Volume: 14 Issue: 1 Pages: 6959-6959
- DOI
  10.1038/s41467-023-42718-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08524, KAKENHI-PROJECT-21K08460, KAKENHI-PROJECT-21H04827, KAKENHI-PROJECT-21H02951, KAKENHI-PROJECT-23K24364
[Journal Article] Targeting a mitochondrial E3 ubiquitin ligase complex to overcome AML cell-intrinsic Venetoclax resistance2023
- Author(s)
  Nakao Fumihiko、Setoguchi Kiyoko、Semba Yuichiro、Yamauchi Takuji、Nogami Jumpei、Sasaki Kensuke、Imanaga Hiroshi、Terasaki Tatsuya、Miyazaki Manaka、Hirabayashi Shigeki、Miyawaki Kohta、Kikushige Yoshikane、Masuda Takeshi、Akashi Koichi、Maeda Takahiro
- Journal Title
  
  Leukemia
  
  Volume: - Issue: 5 Pages: 1028-1038
- DOI
  10.1038/s41375-023-01879-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K16323, KAKENHI-PROJECT-23K24364, KAKENHI-PROJECT-23K07816, KAKENHI-PROJECT-20H05699, KAKENHI-PROJECT-21H04827
[Journal Article] TIM-3 signaling hijacks the canonical Wnt/β-catenin pathway to maintain cancer stemness in acute myeloid leukemia2023
- Author(s)
  Sakoda Teppei、Kikushige Yoshikane、Miyamoto Toshihiro、Irifune Hidetoshi、Harada Takuya、Hatakeyama Kiwamu、Kunisaki Yuya、Kato Koji、Akashi Koichi
- Journal Title
  
  Blood Advances
  
  Volume: - Issue: 10 Pages: 2053-2065
- DOI
  10.1182/bloodadvances.2022008405
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08479, KAKENHI-PROJECT-21H04827, KAKENHI-PROJECT-21H02950, KAKENHI-PROJECT-21H02951, KAKENHI-PROJECT-23K24364
[Journal Article] RHAMM marks proliferative subpopulation of human colorectal cancer stem cells2023
- Author(s)
  Nakano Michitaka、Taguchi Ryosuke、Kikushige Yoshikane、Isobe Taichi、Miyawaki Kohta、Mizuno Shinichi、Tsuruta Nobuhiro、Hanamura Fumiyasu、Yamaguchi Kyoko、Yamauchi Takuji、Ariyama Hiroshi、Kusaba Hitoshi、Nakamura Masafumi、Maeda Takahiro、Kuo Calvin J.、Baba Eishi、Akashi Koichi
- Journal Title
  
  Cancer Science
  
  Volume: - Issue: 7 Pages: 15795-12
- DOI
  10.1111/cas.15795
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07152, KAKENHI-PROJECT-21K07153, KAKENHI-PROJECT-21H04827, KAKENHI-PROJECT-23K24364, KAKENHI-PROJECT-19K16852
[Journal Article] Macrophages are primed to transdifferentiate into fibroblasts in malignant ascites and pleural effusions2022
- Author(s)
  Ito Mamoru、Nakano Michitaka、Ariyama Hiroshi、Yamaguchi Kyoko、Tanaka Risa、Semba Yuichiro、Sugio Takeshi、Miyawaki Kohta、Kikushige Yoshikane、Mizuno Shinichi、Isobe Taichi、Tanoue Kenro、Taguchi Ryosuke、Ueno Shohei、Kawano Takahito、Murata Masaharu、Baba Eishi、Akashi Koichi
- Journal Title
  
  Cancer Letters
  
  Volume: 532 Pages: 215597-215597
- DOI
  10.1016/j.canlet.2022.215597
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21617, KAKENHI-PROJECT-19H03687, KAKENHI-PROJECT-20J00897, KAKENHI-PROJECT-20K08311, KAKENHI-PROJECT-21K07152, KAKENHI-PROJECT-21K12685, KAKENHI-PROJECT-21K18325, KAKENHI-PROJECT-21H04827, KAKENHI-PROJECT-23K24364, KAKENHI-PROJECT-23K25209, KAKENHI-PROJECT-19K16852, KAKENHI-PROJECT-20K17403
[Journal Article] A Germinal Center-Associated Microenvironmental Signature Reflects Malignant Phenotype and Outcome of DLBCL.2022
- Author(s)
  Miyawaki K, Kato K, Sugio T, Sasaki K, Miyoshi H, Semba Y, Kikushige Y, Mori Y, Kunisaki Y, Iwasaki H, Miyamoto T, Kuo FC, Aster JC, Ohshima K, Maeda T, Akashi K.
- Journal Title
  
  Blood Adv.
  
  Volume: 6 Issue: 7 Pages: 2388-2402
- DOI
  10.1182/bloodadvances.2021004618
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08818, KAKENHI-PROJECT-20K21617, KAKENHI-PROJECT-21H04827, KAKENHI-PROJECT-19H03687, KAKENHI-PROJECT-20J00897, KAKENHI-PROJECT-22K19544, KAKENHI-PROJECT-21H02950, KAKENHI-PROJECT-21H02951, KAKENHI-PROJECT-20K07381, KAKENHI-PROJECT-23K24364, KAKENHI-PROJECT-20K17403
[Journal Article] Prognostic value of pre-transplantation total metabolic tumor volume on 18fluoro-2-deoxy-d-glucose positron emission tomography?computed tomography in relapsed and refractory aggressive lymphoma2022
- Author(s)
  Sugio Takeshi、Baba Shingo、Mori Yasuo、Yoshimoto Goichi、Kamesaki Kenjiro、Takashima Shuichiro、Urata Shingo、Shima Takahiro、Miyawaki Kohta、Kikushige Yoshikane、Kunisaki Yuya、Numata Akihiko、Takenaka Katsuto、Iawasaki Hiromi、Miyamoto Toshihiro、Ishigami Kousei、Akashi Koichi、Kato Koji
- Journal Title
  
  International Journal of Hematology
  
  Volume: 116 Issue: 4 Pages: 603-611
- DOI
  10.1007/s12185-022-03394-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08469, KAKENHI-PROJECT-22K08479, KAKENHI-PROJECT-21H04827, KAKENHI-PROJECT-21K20885, KAKENHI-PROJECT-23K24364, KAKENHI-PROJECT-20K17403
[Journal Article] TET2 Clonal Hematopoiesis Is Associated With Anthracycline-Induced Cardiotoxicity in Patients With Lymphoma2022
- Author(s)
  Hatakeyama Kiwamu、Hieda Michinari、Semba Yuichiro、Moriyama Shohei、Wang Yuqing、Maeda Takahiro、Kato Koji、Miyamoto Toshihiro、Akashi Koichi、Kikushige Yoshikane
- Journal Title
  
  JACC: CardioOncology
  
  Volume: 4 Issue: 1 Pages: 141-143
- DOI
  10.1016/j.jaccao.2022.01.098
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21617, KAKENHI-PROJECT-19H03687, KAKENHI-PROJECT-22K19544, KAKENHI-PROJECT-21H04827, KAKENHI-PROJECT-23K24364
[Journal Article] Human acute leukemia utilizes branched-chain amino acid catabolism to maintain stemness through regulating PRC2 function2022
- Author(s)
  Kikushige Yoshikane、Miyamoto Toshihiro、Kochi Yu、Semba Yuichiro、Ohishi Maki、Irifune Hidetoshi、Hatakeyama Kiwamu、Kunisaki Yuya、Sugio Takeshi、Sakoda Teppei、Miyawaki Kohta、Kato Koji、Soga Tomoyoshi、Akashi Koichi
- Journal Title
  
  Blood Advances
  
  Volume: - Issue: 14 Pages: 3592-3603
- DOI
  10.1182/bloodadvances.2022008242
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08479, KAKENHI-PROJECT-21H04827, KAKENHI-PROJECT-21H02950, KAKENHI-PROJECT-23K24364, KAKENHI-ORGANIZER-23H04939, KAKENHI-PROJECT-21H02951, KAKENHI-PROJECT-20K17403
[Journal Article] Risk factors for late cytomegalovirus infection after completing letermovir prophylaxis2022
- Author(s)
  Mori Yasuo、Harada Takuya、Yoshimoto Goichi、Shima Takahiro、Numata Akihiko、Jinnouchi Fumiaki、Yamauchi Takuji、Kikushige Yoshikane、Kunisaki Yuya、Kato Koji、Takenaka Katsuto、Akashi Koichi、Miyamoto Toshihiro
- Journal Title
  
  International Journal of Hematology
  
  Volume: 116 Issue: 2 Pages: 258-265
- DOI
  10.1007/s12185-022-03348-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21H04827, KAKENHI-PROJECT-21H02949, KAKENHI-PROJECT-21H02950, KAKENHI-PROJECT-23K24364
[Journal Article] TIM‐3 in normal and malignant hematopoiesis: Structure, function, and signaling pathways2021
- Author(s)
  Kikushige Yoshikane
- Journal Title
  
  Cancer Science
  
  Volume: 112 Issue: 9 Pages: 3419-3426
- DOI
  10.1111/cas.15042
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21617, KAKENHI-PROJECT-19H03687
[Journal Article] Granulocyte collection by polymorphonuclear cell-targeting apheresis with medium-molecular-weight hydroxyethyl starch2021
- Author(s)
  Henzan Tomoko、Yamauchi Takuji、Yamanaka Ikumi、Sakoda Teppei、Semba Yuichiro、Hayashi Masayasu、Kikushige Yoshikane、Mishima Hiroyuki、Ishimura Masataka、Koga Yuhki、Miyamoto Toshihiro、Ohga Shouichi、Akashi Koichi、Maeda Takahiro、Kunisaki Yuya
- Journal Title
  
  International Journal of Hematology
  
  Volume: 114 Issue: 6 Pages: 691-700
- DOI
  10.1007/s12185-021-03207-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21617, KAKENHI-PROJECT-19H03687, KAKENHI-PROJECT-21H02950
[Journal Article] TKIs induce alternative spliced BCR-ABLIns35bp variant via inhibition of RNA polymerase Ⅱ on genomic BCR-ABL.2020
- Author(s)
  Yuda J, Odawara J, Minami M, Muta T, Kohno K, Tanimoto K, Eto T, Shima T, Kikushige Y, Kato K, Takenaka K, Iwasaki H, Minami Y, Ohkawa Y, Akashi K, Miyamoto T.
- Journal Title
  
  Cancer Sci
  
  Volume: 111 Issue: 7 Pages: 2361-2373
- DOI
  10.1111/cas.14424
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02840, KAKENHI-PROJECT-20K21398, KAKENHI-PUBLICLY-19H05244, KAKENHI-PUBLICLY-20H04846, KAKENHI-PROJECT-16H06391, KAKENHI-PROJECT-20H00456, KAKENHI-PROJECT-19H03687, KAKENHI-PROJECT-19H03424
[Journal Article] Generation of a novel CD30 + B cell subset producing GM-CSF and its possible link to the pathogenesis of systemic sclerosis2020
- Author(s)
  Higashioka K, Kikushige Y, Ayano M, Kimoto Y, Mitoma H, Kikukawa M, Akahoshi M, Arinobu Y, Horiuchi T, Akashi K, Niiro H.
- Journal Title
  
  Clin Exp Immunol.
  
  Volume: 201 Issue: 3 Pages: 233-243
- DOI
  10.1111/cei.13477
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K17887, KAKENHI-PROJECT-16H06391, KAKENHI-PROJECT-19H03687, KAKENHI-PROJECT-18K08410, KAKENHI-PROJECT-19H03564
[Journal Article] Measurable residual disease after the first consolidation predicts the outcomes of patients with acute promyelocytic leukemia treated with all-trans retinoic acid and chemotherapy2020
- Author(s)
  Henzan Hideho、for the Fukuoka Blood & Marrow Transplantation Group (FBMTG)、Takase Ken、Kamimura Tomohiko、Mori Yasuo、Yoshimoto Goichi、Iwasaki Hiromi、Nagafuji Koji、Ogawa Ryosuke、Eto Tetsuya、Uchida Naoyuki、Fujisaki Tomoaki、Kato Koji、Minami Mariko、Kikushige Yoshikane、Akashi Koichi、Miyamoto Toshihiro
- Journal Title
  
  International Journal of Hematology
  
  Volume: 112 Issue: 3 Pages: 349-360
- DOI
  10.1007/s12185-020-02911-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H06391
[Journal Article] Aromatase is a novel neo-substrate of cereblon responsible for immunomodulatory drugs-induced thrombocytopenia. Tochigi T, Miyamoto T, Hatakeyama K, Sakoda T, Ishihara D, Irifune H, Shima T, Kato K, Maeda T, Ito T, Handa H, Akashi K, Kikushige Y.2020
- Author(s)
  Tochigi T, Miyamoto T, Hatakeyama K, Sakoda T, Ishihara D, Irifune H, Shima T, Kato K, Maeda T, Ito T, Handa H, Akashi K, Kikushige Y.
- Journal Title
  
  Blood.
  
  Volume: - Issue: 24 Pages: 2146-2158
- DOI
  10.1182/blood.2019003749
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H06391, KAKENHI-PROJECT-17H06112, KAKENHI-PROJECT-16H05340, KAKENHI-PROJECT-19H03687, KAKENHI-PROJECT-18K19565, KAKENHI-PROJECT-20K21617, KAKENHI-PROJECT-18K08362, KAKENHI-PROJECT-20H05699
[Journal Article] Establishment of a human SIRPA knock-in xenograft mouse model to study human hematopoietic and cancer stem cells2020
- Author(s)
  Jinnouchi Fumiaki、Yamauchi Takuji、Yurino Ayano、Nunomura Takuya、Nakano Michitaka、Iwamoto Chika、Obara Teppei、Miyawaki Kohta、Kikushige Yoshikane、Kato Koji、Maeda Takahiro、Miyamoto Toshihiro、Baba Eishi、Akashi Koichi、Takenaka Katsuto
- Journal Title
  
  Blood
  
  Volume: - Issue: 19 Pages: 1661-1672
- DOI
  10.1182/blood.2019002194
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K16366, KAKENHI-PROJECT-16H06391, KAKENHI-PROJECT-16H05340, KAKENHI-PROJECT-18H02840, KAKENHI-PROJECT-19H03687, KAKENHI-PROJECT-18K19565, KAKENHI-PROJECT-19K08818, KAKENHI-PROJECT-18K08362, KAKENHI-PROJECT-20H05699
[Journal Article] Pathogenesis of chronic lymphocytic leukemia and the development of novel therapeutic strategies2020
- Author(s)
  Kikushige Yoshikane
- Journal Title
  
  Journal of Clinical and Experimental Hematopathology
  
  Volume: 60 Issue: 4 Pages: 146-158
- DOI
  10.3960/jslrt.20036
- NAID
  130007955997
- ISSN
  1346-4280, 1880-9952
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03687
[Journal Article] Anti-GPRC5D/CD3 Bispecific T-Cell-Redirecting Antibody for the Treatment of Multiple Myeloma.2019
- Author(s)
  Kodama T, Kochi Y, Nakai W, Mizuno H, Baba T, Habu K, Sawada N, Tsunoda H, Shima T, Miyawaki K, Kikushige Y, Mori Y, Miyamoto T, Maeda T, Akashi K.
- Journal Title
  
  Molecular Cancer Therapeutics
  
  Volume: 18 Issue: 9 Pages: 1555-1564
- DOI
  10.1158/1535-7163.mct-18-1216
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H06391, KAKENHI-PROJECT-16H05340, KAKENHI-PROJECT-19H03687
[Journal Article] E-cadherin regulates proliferation of colorectal cancer stem cells through NANOG.2018
- Author(s)
  Tamura S, Isobe T, Ariyama H, Nakano M, Kikushige Y, Takaishi S, Kusaba H, Takenaka K, Ueki T, Nakamura M, Akashi K, Baba E.
- Journal Title
  
  Oncology Reports
  
  Volume: 40 (2) Pages: 693-703
- DOI
  10.3892/or.2018.6464
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09460, KAKENHI-PROJECT-18H02840, KAKENHI-PROJECT-16H06250
[Journal Article] Dedifferentiation process driven by TGF-beta signaling enhances stem cell properties in human colorectal cancer2018
- Author(s)
  Nakano Michitaka、Kikushige Yoshikane、Miyawaki Kohta、Kunisaki Yuya、Mizuno Shinichi、Takenaka Katsuto、Tamura Shingo、Okumura Yuta、Ito Mamoru、Ariyama Hiroshi、Kusaba Hitoshi、Nakamura Masafumi、Maeda Takahiro、Baba Eishi、Akashi Koichi
- Journal Title
  
  Oncogene
  
  Volume: 38 Issue: 6 Pages: 780-793
- DOI
  10.1038/s41388-018-0480-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H06391, KAKENHI-PROJECT-18H02841, KAKENHI-PROJECT-16H06250, KAKENHI-PROJECT-18H02840
[Journal Article] Human herpes virus-6-associated encephalitis/myelitis mimicking calcineurin inhibitor induced pain syndrome in allogeneic stem cell transplantation recipients.2018
- Author(s)
  Yoshimoto G, Mori Y, Kato K, Shima T, Miyawaki K, Kikushige Y, Kamezaki K, Numata A, Maeda T, Takenaka K, Iwasaki H, Teshima T, Akashi K, Miyamoto T
- Journal Title
  
  Biol Blood Marrow Transplant
  
  Volume: 24 Issue: 12 Pages: 2540-2548
- DOI
  10.1016/j.bbmt.2018.07.017
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05340, KAKENHI-PROJECT-16H06250
[Journal Article] Identification of unipotent megakaryocyte progenitors in human hematopoiesis.2017
- Author(s)
  K. Miyawaki. Iwasaki, T. Jiromaru, H. Kusumoto, A. Yurino, T. Sugio, Y. Uehara, J. Odawara, S. Daitoku, Y. Kunisaki, Y. Mori, Y. Arinobu, H. Tsuzuki, Y. Kikushige, T. Iino, K. Kato, K. Takenaka, T. Miyamoto, T. Maeda, *K. Akashi
- Journal Title
  
  Blood
  
  Volume: 印刷中 Issue: 25 Pages: 3332-3343
- DOI
  10.1182/blood-2016-09-741611
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-26115009, KAKENHI-PROJECT-15H04859, KAKENHI-PROJECT-15K15364, KAKENHI-PROJECT-16K09897, KAKENHI-PROJECT-16H06391, KAKENHI-PROJECT-17H01567, KAKENHI-PROJECT-16H05340, KAKENHI-PROJECT-16H06250, KAKENHI-PROJECT-15K15365, KAKENHI-PROJECT-16K19578
[Journal Article] Mobilization of human immature hematopoietic progenitors through combinatory use of bortezomib and immunomodulatory drugs.2017
- Author(s)
  T. Tochigi, T. Aoki, *Y. Kikushige, T. Kamimura, Y. Ito, T. Shima, T. Yamauchi, Y. Mori, G. Yoshimoto, K. Kamezaki, K. Kato, K. Takenaka, H. Iwasaki, K. Akashi, T. Miyamoto
- Journal Title
  
  Int J Hematol
  
  Volume: 105 Issue: 4 Pages: 423-432
- DOI
  10.1007/s12185-016-2148-2
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-26115009, KAKENHI-PROJECT-16H06250, KAKENHI-PROJECT-15K09455
[Journal Article] Enhanced Reconstitution of Human Erythropoiesis and Thrombopoiesis in an Immunodeficient Mouse Model with Kit(Wv) Mutations.2016
- Author(s)
  A. Yurino, K. Takenaka, T. Yamauchi, T. Nunomura, Y. Uehara, F. Jinnouchi, K. Miyawaki, Y. Kikushige, K. Kato, T. Miyamoto, H. Iwasaki, Y. Kunisaki, *K. Akashi
- Journal Title
  
  Stem Cell Reports
  
  Volume: 7 Issue: 3 Pages: 425-438
- DOI
  10.1016/j.stemcr.2016.07.002
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-26115009, KAKENHI-PROJECT-16H06391, KAKENHI-PROJECT-15H04859, KAKENHI-PROJECT-16H05340, KAKENHI-PROJECT-16H06250, KAKENHI-PROJECT-26461424, KAKENHI-PROJECT-15K15364, KAKENHI-PROJECT-16K09875, KAKENHI-PROJECT-15K15365
[Journal Article] A TIM-3/Gal-9 Autocrine Stimulatory Loop Drives Self-Renewal of Human Myeloid Leukemia Stem Cells and Leukemic Progression.2015
- Author(s)
  Kikushige Y, Miyamoto T, Yuda J, Jabbarzadeh-Tabrizi S, Shima T, Takayanagi S, Niiro H, Yurino A, Miyawaki K, Takenaka K, Iwasaki H, Akashi K
- Journal Title
  
  Cell Stem Cell.
  
  Volume: 17 Issue: 3 Pages: 341-352
- DOI
  10.1016/j.stem.2015.07.011
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09528, KAKENHI-PROJECT-26461424, KAKENHI-PROJECT-15K15365, KAKENHI-ORGANIZER-22130001, KAKENHI-PLANNED-26115009, KAKENHI-PROJECT-25253069, KAKENHI-PROJECT-25461424, KAKENHI-PROJECT-26713034
[Presentation] DNMT3B maintains the organoid-formation ability of left-sided colorectal cancer derived from patients2022
- Author(s)
  Ryosuke Taguchi, Isobe Taichi, Yoshikane Kikushige, Shohei Ueno, Kenji Tsuchihashi, Hiroshi Ariyama, Koichi Akashi, Eishi Baba
- Organizer
  第81回　日本癌学会学術集会
- Data Source
  KAKENHI-PROJECT-21K07152
[Presentation] DNMT3B contributes to the stemness of left-sided colorectal cancer derived from patients2022
- Author(s)
  Ryosuke Taguchi, Isobe Taichi, Yoshikane Kikushige, Shohei Ueno, Kenji Tsuchihashi, Hiroshi Ariyama, Koichi Akashi, Eishi Baba
- Organizer
  第19回　幹細胞シンポジウム
- Data Source
  KAKENHI-PROJECT-21K07152
[Presentation] Identification of the enhanced lipid metabolism pathway in leukemic stem cells2021
- Author(s)
  菊繁吉謙
- Organizer
  第８０回日本癌学会学術総会　コアシンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-20K21617
[Presentation] ヒト急性白血病における幹細胞性維持機構としての分岐鎖アミノ酸代謝経路2021
- Author(s)
  菊繁吉謙
- Organizer
  第４４回分子生物学会　ワークショップ
- Invited
- Data Source
  KAKENHI-PROJECT-19H03687
[Presentation] ヒト急性白血病における幹細胞性維持機構としての分岐鎖アミノ酸代謝経路2021
- Author(s)
  菊繁吉謙
- Organizer
  第４４回分子生物学会　ワークショップ
- Invited
- Data Source
  KAKENHI-PROJECT-20K21617
[Presentation] Identification of the enhanced lipid metabolism pathway in leukemic stem cells2021
- Author(s)
  菊繁吉謙
- Organizer
  第８０回日本癌学会学術総会　コアシンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-19H03687
[Presentation] Stem Cells in Acute Myeloid Leukemia2020
- Author(s)
  Yoshikane Kikushige, Koichi Akashi
- Organizer
  11th Eurasian Hematology-Oncology Congress, EHOG-JSH joint symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06391
[Presentation] Stem Cells in Acute Myeloid Leukemia2020
- Author(s)
  Yoshikane Kikushige, Koichi Akashi
- Organizer
  11th Eurasian Hematology-Oncology Congress, EHOG-JSH joint symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03687
[Presentation] Identification of BCAAs metabolism pathway as a critical metabolic machinery for the maintenance of human acute leukemia-initiating cells2020
- Author(s)
  菊繁吉謙　赤司浩一
- Organizer
  第７９回日本癌学会学術総会　コアシンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-16H06391
[Presentation] ヒト急性白血病に共通する幹細胞性維持機構としてのアミノ酸代謝経路の解明2020
- Author(s)
  菊繁吉謙　赤司浩一
- Organizer
  第９３回日本生化学学会　シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-16H06391
[Presentation] Evaluation of residual TIM-3+ LSC is a promising approach to predict the clinical outcome of allo-SCT2020
- Author(s)
  Yoshikane Kikushige, Koichi Akashi
- Organizer
  25th Congress of European Hematology Association, EHA-JSH joint symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06391
[Presentation] Identification of BCAAs metabolism pathway as a critical metabolic machinery for the maintenance of human acute leukemia-initiating cells2020
- Author(s)
  菊繁吉謙　赤司浩一
- Organizer
  第７９回日本癌学会学術総会　コアシンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-19H03687
[Presentation] Evaluation of residual TIM-3+ LSC is a promising approach to predict the clinical outcome of allo-SCT2020
- Author(s)
  Yoshikane Kikushige, Koichi Akashi
- Organizer
  25th Congress of European Hematology Association, EHA-JSH joint symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03687
[Presentation] ヒト急性白血病に共通する幹細胞性維持機構としてのアミノ酸代謝経路の解明2020
- Author(s)
  菊繁吉謙　赤司浩一
- Organizer
  第９３回日本生化学学会　シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-19H03687
[Presentation] Identification of BCAAs metabolism pathway as a critical metabolic machinery for the maintenance of human acute leukemia-initiating cells2020
- Author(s)
  菊繁吉謙　赤司浩一
- Organizer
  第８２回日本血液学会学術集会　シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-19H03687
[Presentation] Identification of BCAAs metabolism pathway as a critical metabolic machinery for the maintenance of human acute leukemia-initiating cells2020
- Author(s)
  菊繁吉謙　赤司浩一
- Organizer
  第８２回日本血液学会学術集会シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-16H06391
[Presentation] Identification of BCAAs metabolism pathway as a critical metabolic machinery for the maintenance of human acute leukemia-initiating cells2019
- Author(s)
  菊繁吉謙
- Organizer
  第８１回日本血液学会学術集会　プレナリーセッション
- Invited
- Data Source
  KAKENHI-PROJECT-19H03687
[Presentation] ヒト急性白血病幹細胞における幹細胞性維持機構としての代謝特性の解明2019
- Author(s)
  菊繁吉謙
- Organizer
  第４２回分子生物学会　ワークショップ
- Invited
- Data Source
  KAKENHI-PROJECT-19H03687
[Presentation] ヒト急性白血病幹細胞における幹細胞性維持機構としての代謝特性の解明2019
- Author(s)
  菊繁吉謙
- Organizer
  第１回日本医学連合　若手リトリート
- Invited
- Data Source
  KAKENHI-PROJECT-19H03687
[Presentation] ト急性白血病幹細胞における幹細胞性維持機構としての代謝特性の解明2018
- Author(s)
  菊繁　吉謙
- Organizer
  第１回日本医学連合　若手リトリート
- Invited
- Data Source
  KAKENHI-PROJECT-16H06250
[Presentation] ヒト白血病幹細胞における幹細胞性維持機構としての分枝鎖アミノ酸経路の同定2018
- Author(s)
  菊繁　吉謙
- Organizer
  第６回　がんと代謝研究会
- Invited
- Data Source
  KAKENHI-PROJECT-16H06250
[Presentation] Metabolic machineries for maintaining stemness in human acute leukemia-initiating cells2018
- Author(s)
  Yoshikane Kikushige
- Organizer
  US-Japan Symposium on Normal/Malignant Hematopoiesis and Novel Therapies for Hematological Malignancies
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06250
[Presentation] Identification of BCAAs metabolism pathway as a critical metabolic machinery for the maintenance of human acute leukemia stem cells2018
- Author(s)
  菊繁　吉謙
- Organizer
  第７７回日本癌学会学術総会　コアシンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-16H06250
[Presentation] TIM-3/galectin-9 autocrine loop enhances self-renewal capacity of human leukemic stem cells through mimicking canonical Wnt signaling2017
- Author(s)
  Yoshikane Kikushige
- Organizer
  2017 US-Japan Symposium on Normal/Malignant Hematopoiesis and Novel Therapies for Hematological Malignancies
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06250
[Presentation] 白血病幹細胞研究の進歩と幹細胞を標的とした治療2017
- Author(s)
  菊繁吉謙
- Organizer
  日本血液学会総会　特別教育講演
- Invited
- Data Source
  KAKENHI-PROJECT-16H06250
[Presentation] TIM-3/galectin-9 autocrine loop enhances self-renewal capacity of human leukemic stem cells through mimicking canonical Wnt signaling2017
- Author(s)
  菊繁吉謙、宮本敏浩、赤司浩一
- Organizer
  US-Japan Symposium on Normal/Malignant Hematopoiesis and Novel Therapies for Hematologica Malignancies
- Place of Presentation
  Hawaii, USA
- Year and Date
  2017-02-21
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05340
[Presentation] TIM-3/Gal-9 signaling enhances self-renewal capacity of AML-LSCs through mimicking canonical Wnt signaling2016
- Author(s)
  迫田哲平、菊繁吉謙、宮本敏浩、赤司浩一
- Organizer
  59th American Society of Hematolgy Annual Meeting
- Place of Presentation
  San Diego, USA
- Year and Date
  2016-12-02
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05340
[Presentation] A TIM-3/Gal-9 autocrine stimulatory loop drives self-renewal of human myeloid leukemia stem cells and leukemic progression2016
- Author(s)
  菊繁吉謙
- Organizer
  第７５回日本癌学会学術総会　腫瘍別シンポジウム
- Place of Presentation
  横浜
- Year and Date
  2016-10-08
- Invited
- Data Source
  KAKENHI-PROJECT-16H06250
[Presentation] A TIM-3/Gal-9 autocrine stimulatory loop drives self-renewal of human myeloid leukemia stem cells and leukemic progression2016
- Author(s)
  菊繁吉謙、宮本敏浩、赤司浩一
- Organizer
  45th Annual Scientific Meeting of International Society of Experimental Hematology (ISEH),
- Place of Presentation
  San Diego, USA
- Year and Date
  2016-08-27
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05340
[Presentation] Identification of TIM-3 as a functional leukemic stem cell surface molecule in primary human myeloid leukemia2016
- Author(s)
  菊繁吉謙
- Organizer
  20th Winter Meeting of the Korean Society of Blood and Marrow Transplantation
- Place of Presentation
  韓国　ピョンチャン
- Year and Date
  2016-02-26
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26713034
[Presentation] A TIM-3/Gal-9 autocrine stimulatory loop drives self-renewal of human myeloid leukemia stem cells and leukemic progression2016
- Author(s)
  菊繁吉謙
- Organizer
  International Society of Experimental Hematology (ISEH)
- Place of Presentation
  San Diego, USA
- Year and Date
  2016-08-27
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06250
[Presentation] A TIM-3/Gal-9 autocrine stimulatory loop drives self-renewal of human myeloid leukemia stem cells and leukemic progression2016
- Author(s)
  菊繁吉謙、宮本敏浩、赤司浩一
- Organizer
  第７５回日本癌学会学術総会　腫瘍別シンポジウム
- Place of Presentation
  横浜
- Year and Date
  2016-10-08
- Invited
- Data Source
  KAKENHI-PROJECT-16H05340
[Presentation] 白血病幹細胞におけるTIM-3/galectin-9 オートクラインシグナル機構の解明2015
- Author(s)
  菊繁吉謙
- Organizer
  日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2015-10-09
- Invited
- Data Source
  KAKENHI-PROJECT-26713034
[Presentation] 白血病幹細胞抗原TIM-3の機能解明、および新規標的治療の開発2015
- Author(s)
  菊繁吉謙
- Organizer
  日本癌治療学会学術集会
- Place of Presentation
  京都
- Year and Date
  2015-10-29
- Invited
- Data Source
  KAKENHI-PROJECT-26713034
[Presentation] TIM-3 and its ligand, galectin-9 constitute a pan-myeloid autocrine loop to develop and maintain malignant stem cells in most human myeloid leukemia2015
- Author(s)
  菊繁吉謙
- Organizer
  日本血液学会学術集会
- Place of Presentation
  金沢
- Year and Date
  2015-10-18
- Invited
- Data Source
  KAKENHI-PROJECT-26713034
[Presentation] TIM-3, a leukemia stem cell marker, plays a role in leukemic transformation through autocrine stimulatory signaling by its ligand, galectin-92014
- Author(s)
  菊繁吉謙
- Organizer
  日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2014-09-26
- Invited
- Data Source
  KAKENHI-PROJECT-26713034
[Presentation] TIM-3 and its ligand, galectin-9 constitute a pan-myeloid autocrine loop to develop and maintain malignant stem cells in most human myeloid leukemia2014
- Author(s)
  菊繁吉謙
- Organizer
  米国血液学会
- Place of Presentation
  サンフランシスコ
- Year and Date
  2014-12-09
- Data Source
  KAKENHI-PROJECT-26713034
[Presentation] TIM-3 and its ligand, galectin-9, constitute an autocrine loop universally critical for development of human myeloid leukemia stem cells2014
- Author(s)
  菊繁吉謙
- Organizer
  分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2014-11-27
- Invited
- Data Source
  KAKENHI-PROJECT-26713034

1. AKASHI KOICHI (80380385)

# of Collaborated Projects: 8 results

# of Collaborated Products: 27 results
2. Miyamoto Toshihiro (70343324)

# of Collaborated Projects: 6 results

# of Collaborated Products: 15 results
3. 竹中克斗 (30301295)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
4. 国崎祐哉 (80737099)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
5. 山内拓司 (20796213)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 加藤光次 (20571764)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
7. 森康雄 (90573345)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
8. Takahiro Maeda (00791972)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. Numata Akihiko (60423563)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. Isobe Taichi (30838727)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
11. 曽我朋義 (60338217)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 仙波雄一郎 (90816787)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 高嶋秀一郎 (70622116)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
14. 小田原淳 (30825154)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 迫田哲平 (70898973)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. ARAI Fumio

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. MIZUNO Shinichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. NIIRO Hiroaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 高石繁生

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 綾野雅宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 川上純

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 古賀智裕

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 平林茂樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 岩本千佳

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kikushige Yoshikane 菊繁 吉謙

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Elucidation of leukemic stem cell-specific mitochondrial activation mechanisms and establishment of novel therapeutic approach against AMLPrincipal Investigator

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Establishment of novel therapeutic strategies against cancers via identification of neosubstrate of IMiDsPrincipal Investigator

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Identification of human acute leukemia specific metabolic pathwaysPrincipal Investigator

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Kikushige Yoshikane 菊繁吉謙