kitagawa norio 北河憲雄

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Kitagawa Norio 北河憲雄

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Researcher Number	40628517
Other IDs
Affiliation (Current)	2025: 東京科学大学, 大学院医歯学総合研究科, 准教授
Affiliation (based on the past Project Information) *help	2024: 東京医科歯科大学, 大学院医歯学総合研究科, 講師 2022: 東京医科歯科大学, 大学院医歯学総合研究科, 講師 2017 – 2021: 福岡歯科大学, 口腔歯学部, 講師 2016: 福岡歯科大学, 口腔歯学部, 助教 2014 – 2015: 福岡歯科大学, 歯学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 57030:Conservative dentistry-related / General anatomy (including histology/embryology) / Surgical dentistry Except Principal Investigator Basic Section 57020:Oral pathobiological science-related / General anatomy (including histology/embryology)
Keywords	Principal Investigator 抗菌ペプチド / 細胞骨格 / ケラチノサイト / 癌 / 細胞競合 / 口蓋粘膜 / 上顎骨歯槽突起 / 上顎骨口蓋突起 / 歯周病 / 大口蓋動脈 … More / エクソソーム / 解剖学 / 組織学 / exosome / liquid factor / cell competition / cancer / cell-competition / coculture / necrosis / coculture technique / intermediate filament / antimicrobial peptide / nisin / macropinocytosis / keratinocyte / 口腔潜在的悪性疾患 / Nisin / がん微小環境 / ケラチン17 / 中間径フィラメント / ケラチン１７ / ケラチン５ / Macropinocytosis / EDAC / 細胞間結合 / タイト結合 / 中間系フィラメント / 非角化細胞 / 角化細胞 / vimentin / Cytokeratin 17 / Vimentin / Filamin … More Except Principal Investigator 側方浸潤 / 浸潤 / 浸潤増殖 / 乳頭腫 / 上皮内癌 / 前癌病変 / 出血 / 酸化ストレス / 循環不全 / 異角化 / 扁平苔癬 / 扁平上皮癌 / 細胞競合 / 細胞死 / 口腔がん / 三次元培養 / 重層扁平上皮 / クローディン / タイト結合 Less

Clarification of the course of the major palatine artery," clinical anatomy from normal to periodontal disease and atherosclerosis.Principal Investigator
- Principal Investigator
  
  北河憲雄
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57030:Conservative dentistry-related
- Research Institution
  Tokyo Medical and Dental University
Cell competition at the lateral invasion front of oral squamous cell carcinoma
- Principal Investigator
  
  Saku Takashi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57020:Oral pathobiological science-related
- Research Institution
  Fukuoka Dental College
Does "humoral anticancer factor" secreted by normal epithelium cooperate with "cell competition" for cancer protection?Principal Investigator
- Principal Investigator
  
  Kitagawa Norio
- Project Period (FY)
  2017 – 2022
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General anatomy (including histology/embryology)
- Research Institution
  Tokyo Medical and Dental University
  Fukuoka Dental College
"cancer vs. normal cells." Study on the role of tight junction in cell competition.Principal Investigator
- Principal Investigator
  
  Kitagawa Norio
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  Fukuoka Dental College
Examination of the effect of claudin-7 on squamous cell carcinoma using three dimensional culture
- Principal Investigator
  
  inai Tetsuichiro
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General anatomy (including histology/embryology)
- Research Institution
  Fukuoka Dental College

All 2022 2020 2019 2018 2017 2016 2014 Other

All Journal Article Presentation Book

[Book] ヒト上皮組織に対する抗菌ペプチドの作用、抗菌ペプチドの機能解明と利用技術、第Ⅲ編第5章2017
- Author(s)
  北河　憲雄
- Total Pages
  8
- Publisher
  シーエムシー出版
- ISBN
  9784781312453
- Data Source
  KAKENHI-PROJECT-15K21564
[Journal Article] Antimicrobial peptide nisin induces spherical distribution of macropinocytosis-like cytokeratin 5 and cytokeratin 17 following immediate derangement of the cell membrane2022
- Author(s)
  Kitagawa Norio
- Journal Title
  
  Anatomy & Cell Biology
  
  Volume: 55 Issue: 2 Pages: 190-204
- DOI
  10.5115/acb.21.168
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K18302
[Journal Article] Keratin 17-positive Civatte bodies in oral lichen planus?distribution variety, diagnostic significance and histopathogenesis2020
- Author(s)
  Abe Tatsuya、Kitagawa Norio、Yoshimoto Shohei、Maruyama Satoshi、Yamazaki Manabu、Inai Tetsuichiro、Hashimoto Shuichi、Saku Takashi
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 14586-14586
- DOI
  10.1038/s41598-020-71496-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10101, KAKENHI-PROJECT-17K18302, KAKENHI-PROJECT-18K09533, KAKENHI-PROJECT-18K09740
[Journal Article] The reduced susceptibility of mouse keratinocytes to retinoic acid may be involved in the keratinization of oral and esophageal mucosal epithelium.2019
- Author(s)
  Miyazono S, Otani T, Ogata K, Kitagawa N, Iida H, Inai Y, Matsuura T, Inai T
- Journal Title
  
  Histochemistry and Cell Biology
  
  Volume: 153 Issue: 4 Pages: 225-237
- DOI
  10.1007/s00418-020-01845-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H02111, KAKENHI-PROJECT-17K18302, KAKENHI-PROJECT-19K19305
[Journal Article] Nisin, a food preservative produced by Lactococcus lactis, affects the localization pattern of intermediate filament protein in HaCaT cells2018
- Author(s)
  Kitagawa Norio、Otani Takahito、Inai Tetsuichiro
- Journal Title
  
  Anatomical Science International
  
  Volume: 94 Issue: 2 Pages: 163-171
- DOI
  10.1007/s12565-018-0462-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K18302, KAKENHI-PROJECT-26305032, KAKENHI-PROJECT-17H02111
[Journal Article] Ochratoxin A, citrinin and deoxynivalenol decrease claudin- 2 expression in mouse rectum CMT93-II cells2018
- Author(s)
  Hideaki Nakayama Norio Kitagawa Takahito Otani Hiroshi Iida Hisashi Anan Tetsuichiro Inai
- Journal Title
  
  Microscopy
  
  Volume: 67 Issue: 2 Pages: 99-111
- DOI
  10.1093/jmicro/dfy005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K21564, KAKENHI-PROJECT-15K07128, KAKENHI-PROJECT-17H02111
[Journal Article] Serum affects keratinization and tight junctions in three-dimensional cultures of the mouse keratinocyte cell line COCA through retinoic acid receptor-mediated signaling2018
- Author(s)
  Ozaki Akane、Otani Takahito、Kitagawa Norio、Ogata Kayoko、Iida Hiroshi、Kojima Hiroshi、Inai Tetsuichiro
- Journal Title
  
  Histochemistry and Cell Biology
  
  Volume: 151 Issue: 4 Pages: 315-326
- DOI
  10.1007/s00418-018-1741-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K18302, KAKENHI-PROJECT-26305032, KAKENHI-PROJECT-17H02111
[Journal Article] Formation of keratinocyte multilayers on filters under airlifted or submerged culture conditions in medium containing calcium, ascorbic acid, and keratinocyte growth factor2016
- Author(s)
  Seo A, Kitagawa N, Matsuura T, Sato H, Inai T
- Journal Title
  
  Histochem Cell Biol
  
  Volume: 146 Issue: 5 Pages: 585-597
- DOI
  10.1007/s00418-016-1472-1
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25463044, KAKENHI-PROJECT-26460285, KAKENHI-PROJECT-15K21564
[Journal Article] Kitagawa N1, Inai Y, Higuchi Y, Iida H, Inai T. Inhibition of JNK in HaCaT cells induced tight junction formation with decreased expression of cytokeratin 5, cytokeratin 17 and desmoglein 32014
- Author(s)
  Kitagawa N1, Inai Y, Higuchi Y, Iida H, Inai T
- Journal Title
  
  Histochemistry and Cell Biology
  
  Volume: 142 Issue: 4 Pages: 389-399
- DOI
  10.1007/s00418-014-1219-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24570073, KAKENHI-PROJECT-26460285
[Journal Article] p38 Mitogen-activated protein kinase and c-Jun NH2-terminal protein kinase regulate the accumulation of a tight junction protein, ZO-1, in cell-cell contacts in HaCaT cells2014
- Author(s)
  Minakami M, Kitagawa N, Iida H3 Anan H, Inai T
- Journal Title
  
  Tissue Cell
  
  Volume: 47 Issue: 1 Pages: 1-9
- DOI
  10.1016/j.tice.2014.10.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24570073, KAKENHI-PROJECT-26460285
[Presentation] ケラチノサイトに対する抗菌ペプチドの作用2020
- Author(s)
  北河憲雄、大谷崇仁、緒方佳代子、稲井哲一朗
- Organizer
  第125回日本解剖学会総会・全国学術集会
- Data Source
  KAKENHI-PROJECT-17K18302
[Presentation] 細胞底面に着目した癌細胞排除機構の研究2020
- Author(s)
  北河憲雄
- Organizer
  第62回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-17K18302
[Presentation] ケラチノサイト細胞塊形成に対する抗菌ペプチド Nisin の作用2019
- Author(s)
  北河憲雄, 大谷崇仁, 緒方佳代子, 稲井哲一朗
- Organizer
  第124回日本解剖学会総会・全国学術集会
- Data Source
  KAKENHI-PROJECT-17K18302
[Presentation] 血清がケラチノサイトの角化，分化およびタイト結合に及ぼす影響についての解析2018
- Author(s)
  尾崎茜, 北河憲雄, 大谷崇仁, 緒方佳代子, 瀬尾皓, 小島寛, 稲井哲一朗
- Organizer
  第45回福岡歯科大学学会総会
- Data Source
  KAKENHI-PROJECT-17K18302
[Presentation] Stress activated mitogen-activated protein kinases affect tight junctions in K38 mouse keratinocyte cells2018
- Author(s)
  Nikaido M, Otani T, Kitagawa N, Iida H, Anan H, Inai T
- Organizer
  20th KACD-JSCD Joint Scientific Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K18302
[Presentation] Effect of antimicrobial peptide Nisin on keratinocytes2018
- Author(s)
  北河憲雄、大谷崇仁、稲井哲一朗
- Organizer
  第123回　日本解剖学会総会
- Data Source
  KAKENHI-PROJECT-17K18302
[Presentation] ケラチノサイト液性因子による癌細胞排除の研究2018
- Author(s)
  北河憲雄, 大谷崇仁, 緒方佳代子, 稲井哲一朗
- Organizer
  第60回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-17K18302
[Presentation] Effect of antimicrobial peptide Nisin on keratinocytes2018
- Author(s)
  Kitagawa N, Otani T, Ogata K, Inai T
- Organizer
  Asia Pacific International Congress of Anatomists
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K18302
[Presentation] ストレス応答MAPキナーゼの活性化によるケラチノサイトのタイト結合についての解析2018
- Author(s)
  二階堂美咲, 北河憲雄, 大谷崇仁, 緒方佳代子, 瀬尾皓, 阿南壽, 稲井哲一朗
- Organizer
  第45回福岡歯科大学学会総会
- Data Source
  KAKENHI-PROJECT-17K18302
[Presentation] ブタケラチノサイトの三次元培養系におけるビタミンA誘導体の作用の解析2017
- Author(s)
  宮園祥爾、北河憲雄、大谷崇仁、松浦尚志、稲井哲一朗
- Organizer
  第73回　日本解剖学会　九州支部学術集会
- Data Source
  KAKENHI-PROJECT-15K21564
[Presentation] マウス大腸上皮細胞CMT93-Ⅱにおけるタイト結合蛋白claudinの局在に対するマイコトキシンの影響2017
- Author(s)
  中山英明、北河憲雄、大谷崇仁、阿南壽、稲井哲一朗
- Organizer
  第44回　福岡歯科大学学会総会
- Data Source
  KAKENHI-PROJECT-15K21564
[Presentation] 上皮単独による癌細胞排除機構の研究2017
- Author(s)
  北河憲雄、大谷崇仁、稲井哲一朗
- Organizer
  第122回日本解剖学会総会・全国学術集会
- Place of Presentation
  長崎大学坂本キャンパス
- Year and Date
  2017-03-28
- Data Source
  KAKENHI-PROJECT-15K21564
[Presentation] Three dimensional culture system of mouse keratinocytes2017
- Author(s)
  尾崎茜、北河憲雄、大谷崇仁、小島寛、稲井哲一朗
- Organizer
  第73回　日本解剖学会　九州支部学術集会
- Data Source
  KAKENHI-PROJECT-17K18302
[Presentation] ビタミンA誘導体による角化抑制の解析2017
- Author(s)
  宮園祥爾、北河憲雄、大谷崇仁、瀬尾皓、松浦尚志、稲井哲一朗
- Organizer
  第44回　福岡歯科大学学会総会
- Data Source
  KAKENHI-PROJECT-15K21564
[Presentation] HaCaT 細胞におけるMitogen-Activated Protein Kinase（MAPK）のタイト結合形成への影響2016
- Author(s)
  水上正彦、北河憲雄、阿南壽、稲井哲一朗
- Organizer
  第23回日本歯科医学会総会
- Place of Presentation
  福岡サンパレス/福岡国際会議場
- Year and Date
  2016-10-21
- Data Source
  KAKENHI-PROJECT-15K21564
[Presentation] 血管内皮タイト結合に対する終末糖化産物の作用2016
- Author(s)
  北河憲雄、稲井哲一朗
- Organizer
  第121回日本解剖学会総会・全国学術集会
- Place of Presentation
  ビッグパレットふくしま
- Year and Date
  2016-03-28
- Data Source
  KAKENHI-PROJECT-26460285
[Presentation] マウス大腸癌由来CMT93-Ⅱ細胞におけるタイト結合蛋白claudinの発現調節について2016
- Author(s)
  中山英明，二階堂美咲，北河憲雄，大谷崇仁，阿南壽，稲井哲一朗
- Organizer
  第43回福岡歯科大学学会総会
- Place of Presentation
  福岡歯科大学本館
- Data Source
  KAKENHI-PROJECT-15K21564
[Presentation] タイト結合膜蛋白 claudin-10b と claudin-15の機能解析2016
- Author(s)
  稲井哲一朗，北河憲雄
- Organizer
  第23回日本歯科医学会総会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2016-10-21
- Data Source
  KAKENHI-PROJECT-26460285
[Presentation] タイト結合膜蛋白 claudin-10b と claudin-15の機能解析2016
- Author(s)
  稲井哲一朗、北河憲雄
- Organizer
  第23回日本歯科医学会総会
- Place of Presentation
  福岡サンパレス/福岡国際会議場
- Year and Date
  2016-10-21
- Data Source
  KAKENHI-PROJECT-15K21564
[Presentation] 血管内皮タイト結合に対する終末糖化産物の作用2016
- Author(s)
  北河憲雄、稲井哲一朗
- Organizer
  第121回日本解剖学会総会・全国学術集会
- Place of Presentation
  ビッグパレットふくしま
- Year and Date
  2016-03-28
- Data Source
  KAKENHI-PROJECT-15K21564
[Presentation] ケラチノサイトの細胞骨格に対する食品添加物Nisinの作用2016
- Author(s)
  北河憲雄、大谷崇仁、稲井哲一朗
- Organizer
  第70回日本栄養・食糧学会大会
- Place of Presentation
  武庫川女子大学
- Year and Date
  2016-05-13
- Data Source
  KAKENHI-PROJECT-15K21564
[Presentation] JNK阻害によるケラチノサイトの分化誘導2016
- Author(s)
  北河憲雄、大谷崇仁、稲井哲一朗
- Organizer
  第23回日本歯科医学会総会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2016-10-21
- Data Source
  KAKENHI-PROJECT-15K21564
[Presentation] Analysis of cytoskeleton in normal cells surrounding cancer cells.2016
- Author(s)
  北河憲雄，大谷崇仁，稲井哲一朗
- Organizer
  第58回歯科基礎医学会学術大会
- Place of Presentation
  札幌コンベンションセンター
- Year and Date
  2016-08-24
- Data Source
  KAKENHI-PROJECT-15K21564
[Presentation] 無線LANを活用したｅラーニングによる組織学実習に対する学生の評価
- Author(s)
  畠山雄次、北河憲雄、稲井哲一朗、沢禎彦
- Organizer
  第33回日本歯科医学教育学会総会および学術大会
- Place of Presentation
  北九州国際会議場
- Year and Date
  2014-07-04 – 2014-07-05
- Data Source
  KAKENHI-PROJECT-26460285
[Presentation] HaCaT細胞におけるタイト結合形成とMitogen-Activated Protein Kinase （MAPK）
- Author(s)
  水上正彦、北河憲雄、阿南壽、稲井哲一朗
- Organizer
  第56回歯科基礎医学会学術大会・総会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-26460285
[Presentation] HaCaT細胞のタイト結合形成誘導による基底細胞マーカー発現の変化
- Author(s)
  北河憲雄、稲井哲一朗
- Organizer
  第56回歯科基礎医学会学術大会・総会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-26460285
[Presentation] The effect of Nisin on keratinocyte cytoskeleton and intercellular junction
- Author(s)
  北河憲雄、稲井哲一朗
- Organizer
  第120回日本解剖学会総会・全国学術集会
- Place of Presentation
  神戸国際会議場・展示場
- Year and Date
  2015-03-21 – 2015-03-23
- Data Source
  KAKENHI-PROJECT-26460285

1. inai Tetsuichiro (00264044)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
2. Saku Takashi (40145264)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
3. 阿部達也 (70634856)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. 吉本尚平 (70780188)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. 前川祥吾 (20793574)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. Seo Akira

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 飯田弘

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
8. 松浦尚志

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 佐藤博信

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

kitagawa norio 北河 憲雄

Kitagawa Norio 北河 憲雄

Research Projects

Research Products

Co-Researchers

Clarification of the course of the major palatine artery," clinical anatomy from normal to periodontal disease and atherosclerosis.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Cell competition at the lateral invasion front of oral squamous cell carcinoma

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Does "humoral anticancer factor" secreted by normal epithelium cooperate with "cell competition" for cancer protection?Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

"cancer vs. normal cells." Study on the role of tight junction in cell competition.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Examination of the effect of claudin-7 on squamous cell carcinoma using three dimensional culture

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] ヒト上皮組織に対する抗菌ペプチドの作用、抗菌ペプチドの機能解明と利用技術、第Ⅲ編 第5章2017

Author(s)

Total Pages

Publisher

ISBN

Data Source

[Journal Article] Antimicrobial peptide nisin induces spherical distribution of macropinocytosis-like cytokeratin 5 and cytokeratin 17 following immediate derangement of the cell membrane2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Keratin 17-positive Civatte bodies in oral lichen planus?distribution variety, diagnostic significance and histopathogenesis2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The reduced susceptibility of mouse keratinocytes to retinoic acid may be involved in the keratinization of oral and esophageal mucosal epithelium.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Nisin, a food preservative produced by Lactococcus lactis, affects the localization pattern of intermediate filament protein in HaCaT cells2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Ochratoxin A, citrinin and deoxynivalenol decrease claudin- 2 expression in mouse rectum CMT93-II cells2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Serum affects keratinization and tight junctions in three-dimensional cultures of the mouse keratinocyte cell line COCA through retinoic acid receptor-mediated signaling2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Formation of keratinocyte multilayers on filters under airlifted or submerged culture conditions in medium containing calcium, ascorbic acid, and keratinocyte growth factor2016

Author(s)

Journal Title

DOI

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[Journal Article] Kitagawa N1, Inai Y, Higuchi Y, Iida H, Inai T. Inhibition of JNK in HaCaT cells induced tight junction formation with decreased expression of cytokeratin 5, cytokeratin 17 and desmoglein 32014

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kitagawa norio 北河憲雄

Kitagawa Norio 北河憲雄

[Book] ヒト上皮組織に対する抗菌ペプチドの作用、抗菌ペプチドの機能解明と利用技術、第Ⅲ編第5章2017

[Presentation] ケラチノサイト細胞塊形成に対する抗菌ペプチド Nisin の作用2019