Ohira Takashi 大平宇志

… Alternative Names

OHIRA Takashi 大平宇志

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Researcher Number	40633532
Other IDs
Affiliation (Current)	2025: 国立研究開発法人医薬基盤・健康・栄養研究所, 医薬基盤研究所創薬デザイン研究センター, プロジェクト研究員
Affiliation (based on the past Project Information) *help	2021 – 2023: 近畿大学, 医学部, 助教 2016 – 2019: 国立研究開発法人宇宙航空研究開発機構, 有人宇宙技術部門, 研究開発員 2015: 東京慈恵会医科大学, 医学部, 助教 2014: 独立行政法人宇宙航空研究開発機構, 有人宇宙技術部門, 宇宙航空プロジェクト研究員 2013: 独立行政法人宇宙航空研究開発機構, 有人宇宙ミッション本部, 宇宙航空プロジェクト研究員 2012: 独立行政法人宇宙航空研究開発機構, 有人宇宙ミッション本部, 宇宙航空研究員
Review Section/Research Field	Principal Investigator Basic Section 59040:Nutrition science and health science-related / 0906:Surgery related to the biological and sensory functions and related fields / General physiology / Applied health science / Environmental physiology (including Physical medicine and Nutritional physiology) Except Principal Investigator Complex systems
Keywords	Principal Investigator 骨格筋 / マウス / 筋萎縮 / 線溶系 / 組織線溶 / 非荷重 / 筋・骨連関 / マイオカイン / プロテオミクス / 微小重力 … More / サルコリピン / カルシウムハンドリング / 坐骨神経切除 / 廃用性筋萎縮 / 細胞内シグナル / 肥大・萎縮 / 筋肥大 / 温熱刺激 / タンパク質発現調節 … More Except Principal Investigator 宇宙科学 / 衛生 / 生理学 / 衛生学 / 血圧 / 頭蓋内圧 / 過重力 / 微小重力 / 脳血流 / 循環調節 / 宇宙飛行 / 宇宙医学 Less

The role of fibrinolytic system in unloading-induced skeletal muscle atrophyPrincipal Investigator
- Principal Investigator
  
  大平宇志
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Kindai University
The investigation for the effect of spaceflight on muscle-bone crosstalk in micePrincipal Investigator
- Principal Investigator
  
  Ohira Takashi
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0906:Surgery related to the biological and sensory functions and related fields
- Research Institution
  Kindai University
Changes in calcium handling in denervated skeletal muscles.Principal Investigator
- Principal Investigator
  
  Ohira Takashi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General physiology
- Research Institution
  Japan Aerospace EXploration Agency
Changes in the Cardiovascular Regulatory Mechanism due to Gravitational Variations and Confinement
- Principal Investigator
  
  IWASAKI Kenichi
- Project Period (FY)
  2015 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Nihon University
Effects of heat stimulus on skeletal muscle properties.Principal Investigator
- Principal Investigator
  
  Ohira Takashi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Applied health science
- Research Institution
  Japan Aerospace EXploration Agency
  Jikei University School of Medicine
Investigation of the mechanism responsible for the modulation of myosin heavy chain expression in muscle fibers.Principal Investigator
- Principal Investigator
  
  OHIRA Takashi
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Environmental physiology (including Physical medicine and Nutritional physiology)
- Research Institution
  Japan Aerospace Exploration Agency

All 2024 2023 2022 2018 2016 2015 Other

All Journal Article Presentation

[Journal Article] Plasminogen deficiency exacerbates skeletal muscle loss during mechanical unloading in developing mice2024
- Author(s)
  Ohira Takashi、Ino Yoko、Kawao Naoyuki、Mizukami Yuya、Okada Kiyotaka、Matsuo Osamu、Hirano Hisashi、Kimura Yayoi、Kaji Hiroshi
- Journal Title
  
  Journal of Applied Physiology
  
  Volume: - Issue: 3 Pages: 643-658
- DOI
  10.1152/japplphysiol.00300.2023
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K08642, KAKENHI-PROJECT-23K10947
[Journal Article] Responses of neuromuscular properties to unloading and potential countermeasures during space exploration missions2022
- Author(s)
  Ohira, T., F. Kawano, K. Goto, and Y. Ohira
- Journal Title
  
  Neuroscience and Biobehavioral Reviews
  
  Volume: 136 Pages: 104617-104617
- DOI
  10.1016/j.neubiorev.2022.104617
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07291, KAKENHI-PROJECT-21K21000, KAKENHI-PROJECT-22K19722, KAKENHI-PROJECT-19KK0254, KAKENHI-PROJECT-23K24731
[Journal Article] Effects of Growth Hormone on Muscle and Bone in Female Mice: Role of Follistatin2022
- Author(s)
  Ohira Takashi、Kawao Naoyuki、Takafuji Yoshimasa、Mizukami Yuya、Kaji Hiroshi
- Journal Title
  
  Experimental and Clinical Endocrinology & Diabetes
  
  Volume: 131 Issue: 04 Pages: 228-235
- DOI
  10.1055/a-2003-5704
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K09514, KAKENHI-PROJECT-21K21000
[Presentation] Effects of growth hormone on skeletal muscle and bone in mice2023
- Author(s)
  Naoyuki Kawao, Takashi Ohira, Yuya Mizukami, Yoshimasa Takafuji, Hiroshi Kaji
- Organizer
  日本生理学会第100回記念大会
- Data Source
  KAKENHI-PROJECT-21K21000
[Presentation] 非荷重による筋萎縮時における線溶系因子Plasminogen (Plg)の役割2023
- Author(s)
  大平宇志、井野洋子、河尾直之、水上優哉、岡田清孝、松尾理、平野久、木村弥生、梶博史
- Organizer
  第41回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-23K10947
[Presentation] マウスのヒラメ筋と長趾伸筋の重力変化に対する異なる応答メカニズムの検討2018
- Author(s)
  大平宇志、井野洋子、中居佑介、森田啓之、河野史倫、後藤勝正、大平充宣、木村弥生、平野久
- Organizer
  第64回日本宇宙航空環境医学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-16K18994
[Presentation] DIA法を利用した後肢懸垂マウス血清の定量プロテオーム解析2018
- Author(s)
  中居佑介、木村鮎子、森山佳谷乃、香川裕之、井野洋子、大平宇志、木村弥生、平野久
- Organizer
  第66回質量分析総合討論会・日本プロテオーム学会2018年大会・9th Asia-Oceania Human Proteome Organization (AOHUPO) Conference 合同大会
- Data Source
  KAKENHI-PROJECT-16K18994
[Presentation] 骨格筋タンパク質の比較定量解析手法の確立2018
- Author(s)
  井野洋子、大平宇志、森山佳谷乃、中居佑介、木村鮎子、熊谷研、齋藤知行、森田啓之、木村弥生、平野久
- Organizer
  第66回質量分析総合討論会・日本プロテオーム学会2018年大会・9th Asia-Oceania Human Proteome Organization (AOHUPO) Conference 合同大会
- Data Source
  KAKENHI-PROJECT-16K18994
[Presentation] 宇宙飛行に伴う骨格筋の特性変化とその予防策の検討2016
- Author(s)
  大平宇志、神山慶人、金子祐樹
- Organizer
  第62回日本宇宙航空環境医学会大会　日本宇宙生物科学会第30回大会合同大会
- Place of Presentation
  愛知医科大学
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-26750347
[Presentation] Effects of heat stimulus on skeletal muscle properties2016
- Author(s)
  Takashi Ohira, Masamichi Sudoh, Yoichiro Kusakari, Susumu Minamisawa
- Organizer
  第93回日本生理学会大会
- Place of Presentation
  札幌コンベンションセンター
- Year and Date
  2016-03-22
- Invited
- Data Source
  KAKENHI-PROJECT-26750347
[Presentation] 温熱刺激に対するラットヒラメ筋の応答2015
- Author(s)
  大平宇志, 寺田昌弘, 須藤正道, 草刈洋一郎, 福田紀男, 南沢享
- Organizer
  第132回成医会総会
- Place of Presentation
  東京慈恵会医科大学　大学1号館1階
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-26750347
[Presentation] 長期宇宙滞在に伴う宇宙飛行士の骨格筋機能低下に対する予防策として温熱刺激の有効性の検討2015
- Author(s)
  大平宇志, 寺田昌弘, 須藤正道, 草刈洋一郎, 南沢享
- Organizer
  平成27年筋生理の集い
- Place of Presentation
  東京慈恵会医科大学　高木会館2号館地下1階　南講堂
- Year and Date
  2015-12-19
- Data Source
  KAKENHI-PROJECT-26750347
[Presentation] 温熱刺激が骨格筋量に及ぼす影響2015
- Author(s)
  大平宇志, 寺田昌弘, 須藤正道, 草刈洋一郎, 福田紀男, 南沢享
- Organizer
  第246回生理学東京談話会
- Place of Presentation
  東邦大学医学部1号館8階東邦会館
- Year and Date
  2015-09-26
- Data Source
  KAKENHI-PROJECT-26750347
[Presentation] Responses of skeletal muscle to heat stress2015
- Author(s)
  Takashi Ohira
- Organizer
  The 11th WORLD CONGRESS of the International Society for ADAPTIVE MEDICINE (ISAM 2015)
- Place of Presentation
  米子コンベンションセンター
- Year and Date
  2015-05-27
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26750347
[Presentation] Responses of skeletal muscle to heat stress
- Author(s)
  Takashi Ohira
- Organizer
  The 11th WORLD CONGRESS of the International Society for ADAPTIVE MEDICINE (ISAM 2015)
- Place of Presentation
  Yonago Convention Center, Tottori, Japan
- Year and Date
  2015-05-27 – 2015-05-30
- Invited
- Data Source
  KAKENHI-PROJECT-26750347

1. IWASAKI Kenichi (80287630)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 柳田亮 (00644741)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 小川洋二郎 (60434073)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 田子智晴 (70780229)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 上田要 (00598964)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 青木健 (60332938)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 篠島亜里 (60647189)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 梶博史 (90346255)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
9. 水上優哉

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 河尾直之

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
11. 大平充宣

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Ohira Takashi 大平 宇志

OHIRA Takashi 大平 宇志

Research Projects

Research Products

Co-Researchers

The role of fibrinolytic system in unloading-induced skeletal muscle atrophyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The investigation for the effect of spaceflight on muscle-bone crosstalk in micePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Changes in calcium handling in denervated skeletal muscles.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Changes in the Cardiovascular Regulatory Mechanism due to Gravitational Variations and Confinement

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Effects of heat stimulus on skeletal muscle properties.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Investigation of the mechanism responsible for the modulation of myosin heavy chain expression in muscle fibers.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Plasminogen deficiency exacerbates skeletal muscle loss during mechanical unloading in developing mice2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Responses of neuromuscular properties to unloading and potential countermeasures during space exploration missions2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Effects of Growth Hormone on Muscle and Bone in Female Mice: Role of Follistatin2022

Author(s)

Journal Title

DOI

Data Source

[Presentation] Effects of growth hormone on skeletal muscle and bone in mice2023

Author(s)

Organizer

Data Source

[Presentation] 非荷重による筋萎縮時における線溶系因子Plasminogen (Plg)の役割2023

Author(s)

Organizer

Data Source

[Presentation] マウスのヒラメ筋と長趾伸筋の重力変化に対する異なる応答メカニズムの検討2018

Author(s)

Organizer

Data Source

[Presentation] DIA法を利用した後肢懸垂マウス血清の定量プロテオーム解析2018

Author(s)

Organizer

Data Source

[Presentation] 骨格筋タンパク質の比較定量解析手法の確立2018

Author(s)

Organizer

Data Source

[Presentation] 宇宙飛行に伴う骨格筋の特性変化とその予防策の検討2016

Author(s)

Organizer

Place of Presentation

Ohira Takashi 大平宇志

OHIRA Takashi 大平宇志