Go Unen 呉雲燕

… Alternative Names

Wu Yunyan 呉雲燕

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Researcher Number	40636586
Affiliation (Current)	2025: 自治医科大学, 医学部, 客員研究員
Affiliation (based on the past Project Information) *help	2025: 自治医科大学, 医学部, 客員研究員 2019 – 2022: 自治医科大学, 医学部, ポスト・ドクター 2016 – 2019: 弘前大学, 医学研究科, 助教 2017: 弘前大学, 大学院医学研究科, 助教 2014 – 2015: 弘前大学, 医学(系)研究科(研究院), 助教
Review Section/Research Field	Principal Investigator Basic Section 55010:General surgery and pediatric surgery-related / Basic Section 56070:Plastic and reconstructive surgery-related / Human pathology / General surgery Except Principal Investigator Basic Section 52040:Radiological sciences-related / General anatomy (including histology/embryology) / Human pathology / General surgery
Keywords	Principal Investigator 血管新生 / 癌微小環境 / 時計遺伝子 / ヒト脂肪幹細胞 / 培養上清 / 脂肪由来間質幹細胞 / 再生医療 / ASC / 脂肪由来幹細胞 / 浄化濃縮幹細胞培養上清 … More / 幹細胞培養上清 / 三次元培養 / 脈管新生 / 乳癌 / 上皮間葉転換 / がん微小環境 / 乳腺 … More Except Principal Investigator 時計遺伝子 / 浸潤性増殖 / 乳癌 / ヒト癌細胞 / 微小環境 / MRI / 腫瘍細胞増殖 / 低酸素 / 治療効果 / 放射線画像 / リンパ行性転移 / 血行性転移 / 腫瘍細胞 / 血管新生 / 高悪性度 / 腫瘍 / 細胞・組織 / 癌微小環境 / 上皮間葉転換 / 膵癌 / 胆道癌 / 分子標的治療薬 / 転写因子 / ＴＧＦβ Less

エクソソームフリー脂肪幹細胞セクレトーム（EFSE）による再生療法の開発Principal Investigator
- Principal Investigator
  
  呉雲燕
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Jichi Medical University
A method for detoxifying and concentrating the mesenchmal stem cells' conditioned media and its application in regenerative medicinePrincipal Investigator
- Principal Investigator
  
  Wu Yunyan
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56070:Plastic and reconstructive surgery-related
- Research Institution
  Jichi Medical University
Breast cancer microenvironment control targeting clock gene and its development of MRI imaging
- Principal Investigator
  
  Seino Hiroko
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  Hirosaki University
Functional analysis of clock genes in invasive breast carcinomaPrincipal Investigator
- Principal Investigator
  
  Wu Yunyan
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Human pathology
- Research Institution
  Jichi Medical University
  Hirosaki University
Pathophysiological modulation of high-grade malignant potentials of pancreato-biliary cancer, and its clinical application
- Principal Investigator
  
  KIJIMA Hiroshi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Human pathology
- Research Institution
  Hirosaki University
Breast cancer microenvironment control targeting clock gene and its clinical application
- Principal Investigator
  
  Morohashi Satoko
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Hirosaki University
Functional analysis of "angio-lymphatic vessels" in the neoplastic lesions - its histopathological significance
- Principal Investigator
  
  Kijima Hiroshi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General anatomy (including histology/embryology)
- Research Institution
  Hirosaki University
Functional analysis of clock genes in regulating the microenvironment of breast cancerPrincipal Investigator
- Principal Investigator
  
  Wu Yunyan
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General surgery
- Research Institution
  Hirosaki University

All 2022 2021 2020 2019 2018 2017 2016 2015 2014

All Journal Article Presentation Patent

[Journal Article] Purification and characterization of human adipose-resident microvascular endothelial progenitor cells2022
- Author(s)
  Saito Natsumi、Shirado Takako、Funabashi-Eto Hitomi、Wu Yunyan、Mori Masanori、Asahi Rintaro、Yoshimura Kotaro
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1 Pages: 1775-1775
- DOI
  10.1038/s41598-022-05760-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09850, KAKENHI-PROJECT-20K09851
[Journal Article] Adipose-Derived Stem Cell Conditioned Medium and Wound Healing: A Systematic Review2022
- Author(s)
  Zhang Bihang、Wu Yunyan、Mori Masanori、Yoshimura Kotaro
- Journal Title
  
  Tissue Engineering Part B: Reviews
  
  Volume: - Issue: 4 Pages: 830-847
- DOI
  10.1089/ten.teb.2021.0100
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K09850
[Journal Article] Time density curve of dynamic contrast enhanced computed tomography correlates with histological characteristics of pancreatic cancer2021
- Author(s)
  Shintaro Goto, Hiroko Seino, Tadashi Yoshizawa, Satoko Morohashi, Keinosuke Ishido, Kenichi Hakamada, Hiroshi Kijima.
- Journal Title
  
  Oncology Letters
  
  Volume: 21 Issue: 4 Pages: 276-276
- DOI
  10.3892/ol.2021.12537
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09095, KAKENHI-PROJECT-19K16763, KAKENHI-PROJECT-16K10587, KAKENHI-PROJECT-18K07702, KAKENHI-PROJECT-21H02700, KAKENHI-PROJECT-21K15396
[Journal Article] Sodium Alginate as a Potential Therapeutic Filler: An In Vivo Study in Rats2020
- Author(s)
  Mori Masanori、Asahi Rintaro、Yamamoto Yoshihiro、Mashiko Takanobu、Yoshizumi Kayo、Saito Natsumi、Shirado Takako、Wu Yunyan、Yoshimura Kotaro
- Journal Title
  
  Marine Drugs
  
  Volume: 18 Issue: 10 Pages: 520-520
- DOI
  10.3390/md18100520
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09850
[Journal Article] Type I Collagen Induces DEC Expression and Epithelial-Mesenchymal Transition (EMT) in Human Breast Cancer MCF-7 Cells.2019
- Author(s)
  Tsugeno Y, Yoshizawa T, Wu Y, Goto S, Haga T, Suzuki T, Seino H, Morohashi S, Kijima H.
- Journal Title
  
  BioMed Res J.
  
  Volume: 3 Pages: 125-131
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04057
[Journal Article] Histopathological Characteristics of Pancreatic Cancer Stroma Induced by Neoadjuvant Chemotherapy2019
- Author(s)
  Goto S, Ishido K, Yoshizawa T, Haga T, Morohashi S, Wu Y, Seino H, Hakamada K, Kijima H.
- Journal Title
  
  BioMed Research Journal
  
  Volume: 3 Pages: 61-64
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K17575
[Journal Article] Histopathological Characteristics of Pancreatic Cancer Stroma Induced by Neoadjuvant Chemotherapy.2019
- Author(s)
  Goto S, Ishido K, Yoshizawa T, Haga T, Morohashi S, Wu Y, Seino H, Hakamada K, Kijima H.
- Journal Title
  
  Biomed Res J.
  
  Volume: 3 Pages: 61-64
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04057
[Journal Article] Investigating the association between radiological images and the pathology of rectal cancer treated with neoadjuvant chemotherapy.2019
- Author(s)
  Morohashi S, Morohashi H, Seino H, Yoshizawa T, Haga T, Goto S, Wu Y, Sakamoto Y, Hakamada K, Kijima H
- Journal Title
  
  Mol Clin Oncol.
  
  Volume: 11 Pages: 573-579
- DOI
  10.3892/mco.2019.1931
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10587, KAKENHI-PROJECT-18K07702, KAKENHI-PROJECT-19K16763, KAKENHI-PROJECT-19K17449, KAKENHI-PROJECT-17H04057
[Journal Article] Type I Collagen Induces DEC Expression and Epithelial-Mesenchymal Transition (EMT) in Human Breast Cancer MCF-7 Cells.2019
- Author(s)
  Tsugeno Y, Yoshizawa T, Wu Y, Goto S, Haga T, Suzuki T, Seino H, Morohashi S, Kijima H.
- Journal Title
  
  BioMed Research Journal
  
  Volume: 3 Pages: 125-131
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K17575
[Journal Article] DEC1 and DEC2 Regulate Apoptosis of Human Prostate Adenocarcinoma LNCap Cells2018
- Author(s)
  Qiang Liu、 Yunyan Wu、 Hiroko Seino、 Tadashi Yoshizawa、 Toshihiro Haga、 Satoko Morohashi、 Hiroshi Kijima
- Journal Title
  
  BioMed Research Journal
  
  Volume: 1 Pages: 6-11
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K17575
[Journal Article] Correlation between DEC1/DEC2 and epithelial-mesenchymal transition in human prostate cancer PC-3 cells2018
- Author(s)
  Liu Qiang、Wu Yunyan、Seino Hiroko、Haga Toshihiro、Yoshizawa Tadashi、Morohashi Satoko、Kijima Hiroshi
- Journal Title
  
  Molecular Medicine Reports
  
  Volume: 4 Pages: 3859-3865
- DOI
  10.3892/mmr.2018.9367
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07702, KAKENHI-PROJECT-17K17575, KAKENHI-PROJECT-16K10448, KAKENHI-PROJECT-16K19328
[Journal Article] Toll-like receptor 3 signaling contributes to regional neutrophil recruitment in cultured human glomerular endothelial cells.2018
- Author(s)
  Liu Q, Imaizumi T, Kawaguchi S, Aizawa T, Matsumiya T, Watanabe S, Tsugawa K, Yoshida H, Tsuruga K, Joh K, Kijima H, Tanaka H
- Journal Title
  
  Nephron
  
  Volume: 139 Issue: 4 Pages: 349-358
- DOI
  10.1159/000489507
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09681, KAKENHI-PROJECT-17K10012, KAKENHI-PROJECT-17H04057, KAKENHI-PROJECT-16K10055
[Journal Article] Expression of cancer-associated fibroblast markers in advanced colorectal cancer2018
- Author(s)
  Nishishita Rie、Morohashi Satoko、Seino Hiroko、Wu Yunyan、Yoshizawa Tadashi、Haga Toshihiro、Saito Kensuke、Hakamada Kenichi、Fukuda Shinsaku、Kijima Hiroshi
- Journal Title
  
  Oncol Lett.
  
  Volume: 15 Pages: 6195-6202
- DOI
  10.3892/ol.2018.8097
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10448, KAKENHI-PROJECT-16K19328, KAKENHI-PROJECT-15K15011, KAKENHI-PROJECT-15K19763, KAKENHI-PROJECT-18K07702, KAKENHI-PROJECT-17K17575, KAKENHI-PROJECT-17H04057
[Journal Article] Neoangiogenesis of gastric submucosa-invasive adenocarcinoma2018
- Author(s)
  Sasaki Hanae、Morohashi Satoko、Toba Takahito、Seino Hiroko、Yoshizawa Tadashi、Hirai Hideaki、Haga Toshihiro、Wu Yunyan、Kijima Hiroshi
- Journal Title
  
  Oncology Letters
  
  Volume: 3 Pages: 3895-3900
- DOI
  10.3892/ol.2018.9116
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07702, KAKENHI-PROJECT-17K17575, KAKENHI-PROJECT-17H04057, KAKENHI-PROJECT-16K10448, KAKENHI-PROJECT-16K19072, KAKENHI-PROJECT-16K19328
[Journal Article] Gastric Focal Neutrophil Infiltration and Wide Duodenal Gastric Foveolar Metaplasia Are Histologic Discriminative Markers for Crohn’s Disease and Behcet’s Disease2018
- Author(s)
  Akemoto Yui、Sakuraba Hirotake、Tanaka Masanori、Hiraga Hiroto、Kikuchi Hidezumi、Morohashi Satoko、Ota Shinji、Hasui Keisuke、Satake Miwa、Watanabe Rina、Tanaka Nahoko、Kawaguchi Shogo、Tatsuta Tetsuya、Sawaya Manabu、Chinda Daisuke、Mikami Tatsuya、Ishiguro Yoh、Kijima Hiroshi、Fukuda Shinsaku
- Journal Title
  
  Digestion
  
  Volume: 12 Issue: 3 Pages: 1-10
- DOI
  10.1159/000494922
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10448
[Journal Article] Jaundice as an Initial Manifestation of Pancreatic Dedifferentiated Liposarcoma2018
- Author(s)
  Tadashi Yoshizawa, Satoko Morohashi, Shintaro Goto, Toshihiro Haga, Hiroko Seino, Yunyan Wu, Kenichi Hakamada, Hiroshi Kijima
- Journal Title
  
  Biomed Res J
  
  Volume: 2 Pages: 12-17
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04057
[Journal Article] BHLH Transcription Factors DEC1 and DEC2: From Structure to Various Diseases2018
- Author(s)
  Yunyan Wu, Hiroshi Kijima
- Journal Title
  
  BioMed Research Journal
  
  Volume: 2 Pages: 28-33
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K17575
[Journal Article] BHLH Transcription Factors DEC1 and DEC2: From Structure to Various Diseases2018
- Author(s)
  Yunyan Wu, Hiroshi Kijima
- Journal Title
  
  Biomed Res J
  
  Volume: 2 Pages: 28-33
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04057
[Journal Article] Intraoperative adjunctive mitomycin C and cryotherapy for recurrent conjunctival papillary sebaceous carcinoma2018
- Author(s)
  Monai N, Tanabu R, Gonome T, Yokoi K, Urushidate S, Morohashi S, Hirai H, Kurose A, Nakazawa M
- Journal Title
  
  Case Reports in Ophthalmology
  
  Volume: 9 Issue: 1 Pages: 221-226
- DOI
  10.1159/000487704
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K11313, KAKENHI-PROJECT-17K16954, KAKENHI-PROJECT-16K10448, KAKENHI-PROJECT-16K19072
[Journal Article] Onco-testicular sperm extraction (Onco-TESE) from a single testis with metachronous bilateral testicular cancer: a case report2018
- Author(s)
  Hamano Itsuto、Hatakeyama Shingo、Nakamura Rika、Fukuhara Rie、Noro Daisuke、Seino Hiroko、Yoneyama Takahiro、Hashimoto Yasuhiro、Koie Takuya、Yokoyama Yoshihito、Ohyama Chikara
- Journal Title
  
  Basic and Clinical Andrology
  
  Volume: 28 Issue: 1 Pages: 1-1
- DOI
  10.1186/s12610-018-0066-2
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11118, KAKENHI-PROJECT-17K11119, KAKENHI-PROJECT-17K11263, KAKENHI-PROJECT-18K07702
[Journal Article] Impact of the histological phenotype of extrahepatic bile duct carcinoma2017
- Author(s)
  Okano Kensuke、Yoshizawa Tadashi、Miura Takuya、Ishido Keinosuke、Kudo Daisuke、Kimura Norihisa、Wakiya Taichi、Wu Yunyan、Morohashi Satoko、Hakamada Kenichi、Kijima Hiroshi
- Journal Title
  
  Mol Clin Oncol.
  
  Volume: 8 Pages: 54-60
- DOI
  10.3892/mco.2017.1472
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10448, KAKENHI-PROJECT-17H04057
[Journal Article] Prognostic Impact of Extracapsular Lymph Node Invasion and Myofibroblastic Activity in Extrahepatic Bile Duct Cancer2017
- Author(s)
  Yoshizawa Tadashi、Ishido Keinosuke、Saito Kensuke、Haga Toshihiro、Seino Hiroko、Wu Yunyan、Morohashi Satoko、Hakamada Kenichi、Kijima Hiroshi
- Journal Title
  
  Clin Med Insights Pathol.
  
  Volume: 10 Pages: 1-7
- DOI
  10.1177/1179555717729652
- NAID
  120006583346
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10448, KAKENHI-PROJECT-16K19328, KAKENHI-PROJECT-17K17575, KAKENHI-PROJECT-17H04057, KAKENHI-PROJECT-15K15011, KAKENHI-PROJECT-15K19763
[Journal Article] DEC1 negatively regulates the expression of CXCL10 and CCL5 induced by poly IC in normal human mesangial cells 2017
- Author(s)
 Liu Q, Imaizumi T, Murakami K, Tanaka H, Wu Y, Yoshizawa T, Morohashi S, Seino H, Kijima H
- Journal Title
 
 Biomed. Res.
 
 Volume: 38 Issue: 4 Pages: 249-255
- DOI
 10.2220/biomedres.38.249
- NAID
 130005966979
- ISSN
 0388-6107, 1880-313X
- Language
 English
- Peer Reviewed / Open Access
- Data Source
 KAKENHI-PROJECT-17K09681, KAKENHI-PROJECT-17K17575, KAKENHI-PROJECT-15K19763
[Journal Article] Prognostic Impact of CD163+ Macrophages in Tumor Stroma and CD8+ T-Cells in Cancer Cell Nests in Invasive Extrahepatic Bile Duct Cancer.2017
- Author(s)
  Miura T, Yoshizawa T, Hirai H, Seino H, Morohashi S, Wu Y, Wakiya T, Kimura N, Kudo D, Ishido K, Toyoki Y, Kijima H, Hakamada K.
- Journal Title
  
  Anticancer Res
  
  Volume: 37 Issue: 1 Pages: 183-190
- DOI
  10.21873/anticanres.11304
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H06007, KAKENHI-PROJECT-15K19866, KAKENHI-PROJECT-16K10448, KAKENHI-PROJECT-17K17575
[Journal Article] DEC1 promotes hypoxia-induced epithelial-mesenchymal transition (EMT) in human hepatocellular carcinoma cells 2017
- Author(s)
 Murakami Keishu、Wu Yunyan、Imaizumi Tadaatsu、 Aoki Yuka、Liu Qiang、Yan Xu、Seino Hiroko、Yoshizawa Tadashi、Morohashi Satoko、Kato Yukio、Kijima Hiroshi
- Journal Title
 
 Biomed. Res.
 
 Volume: 38 Issue: 4 Pages: 221-227
- DOI
 10.2220/biomedres.38.221
- NAID
 130005966980
- ISSN
 0388-6107, 1880-313X
- Language
 English
- Peer Reviewed / Open Access
- Data Source
 KAKENHI-PROJECT-17K17575, KAKENHI-PROJECT-17H04057, KAKENHI-PROJECT-15K19763
[Journal Article] DEC2 expression antagonizes cisplatin-induced apoptosis in human esophageal squamous cell carcinoma2017
- Author(s)
  Sato Hidenobu、Wu Yunyan、Kato Yukio、Liu Qiang、Hirai Hideaki、Yoshizawa Tadashi、Morohashi Satoko、Watanabe Jun、Kijima Hiroshi
- Journal Title
  
  Mol Med Rep.
  
  Volume: 16 Issue: 1 Pages: 43-48
- DOI
  10.3892/mmr.2017.6571
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10448, KAKENHI-PROJECT-17K17575, KAKENHI-PROJECT-17H04057
[Journal Article] Contrast media enhancement reduction predicts tumor response to presurgical molecular-targeting therapy in patients with advanced renal cell carcinoma2017
- Author(s)
  Hosogoe Shogo、Hatakeyama Shingo、Kusaka Ayumu、Hamano Itsuto、Tanaka Yoshimi、Hagiwara Kazuhisa、Hirai Hideaki、Morohashi Satoko、Kijima Hiroshi、Yamamoto Hayato、Tobisawa Yuki、Yoneyama Tohru、Yoneyama Takahiro、Hashimoto Yasuhiro、Koie Takuya、Ohyama Chikara
- Journal Title
  
  Oncotarget.
  
  Volume: 8 Issue: 30 Pages: 49749-49756
- DOI
  10.18632/oncotarget.17930
- NAID
  120006583348
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10448, KAKENHI-PROJECT-16K19072
[Journal Article] DEC1 and DEC2 Regulate Apoptosis of Human Prostate Adenocarcinoma LNCap Cells.2017
- Author(s)
  Liu Q, Wu Y, Seino H, Yoshizawa T, Haga T, Morohashi S, Kijima H.
- Journal Title
  
  Biomed Res J.
  
  Volume: 1 Pages: 6-11
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K15011
[Journal Article] DEC1 and DEC2 Regulate Apoptosis of Human Prostate Adenocarcinoma LNCap Cells.2017
- Author(s)
  Liu Q, Wu Y, Seino H, Yoshizawa T, Haga T, Morohashi S, Kijima H.
- Journal Title
  
  Biomed Res J.
  
  Volume: 1 Pages: 6-11
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04057
[Journal Article] Prognostic Impact of CD163+ Macrophages in Tumor Stroma and CD8+ T-Cells in Cancer Cell Nests in Invasive Extrahepatic Bile Duct Cancer.2017
- Author(s)
  Miura T, Yoshizawa T, Hirai H, Seino H, Morohashi S, Wu Y, Wakiya T, Kimura N, Kudo D, Ishido K, Toyoki Y, Kijima H, Hakamada K.
- Journal Title
  
  Anticancer Res.
  
  Volume: 37 Pages: 183-190
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K15011
[Journal Article] Clinicopathological significance of gastric poorly differentiated medullary carcinoma 2016
- Author(s)
 Hirai H, Yoshizawa T, Morohashi S, Haga T, Wu Y, Ota R, Takatsuna M, Akasaka H, Hakamada K, Kijima H.
- Journal Title
 
 Biomed. Res.
 
 Volume: 37 Issue: 2 Pages: 77-84
- DOI
 10.2220/biomedres.37.77
- NAID
 130005147429
- ISSN
 0388-6107, 1880-313X
- Language
 English
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
 KAKENHI-PROJECT-15H06007, KAKENHI-PROJECT-26870028, KAKENHI-PROJECT-16K10448, KAKENHI-PROJECT-16K19328
[Journal Article] Podoplanin-mediated TGF-β-induced epithelial-mesenchymal transition and its correlation with bHLH transcription factor DEC in TE-11 cells.2016
- Author(s)
  Wu Y, Liu Q, Yan X, Kato Y, Tanaka M, Inokuchi S, Yoshizawa T, Morohashi S, Kijima H.
- Journal Title
  
  Int J Oncol.
  
  Volume: 48 Issue: 6 Pages: 2310-2320
- DOI
  10.3892/ijo.2016.3445
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K19763, KAKENHI-PROJECT-15H06007, KAKENHI-PROJECT-26870028, KAKENHI-PROJECT-16K10448
[Journal Article] Myofibroblasts of the muscle layer stimulate the malignant potential of colorectal cancer.2016
- Author(s)
  Takatsuna M, Morohashi S, Yoshizawa T, Hirai H, Haga T, Ota R, Wu Y, Morohashi H, Hakamada K, Terai S, Kijima H.
- Journal Title
  
  Oncol Rep
  
  Volume: 36 Issue: 3 Pages: 1251-1257
- DOI
  10.3892/or.2016.4932
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H06007, KAKENHI-PROJECT-26293175, KAKENHI-PROJECT-26870028, KAKENHI-PROJECT-16K10448, KAKENHI-PROJECT-16K19328
[Journal Article] A new histological therapeutic classification system to predict eradicated and residual lymph nodes in breast cancer after neoadjuvant chemotherapy.2016
- Author(s)
  Morohashi S, Yoshizawa T, Seino H, Hirai H, Haga T, Ota R, Wu Y, Yoshida E, Hakamada K, Kijima H.
- Journal Title
  
  Oncol Rep.
  
  Volume: 35 Issue: 5 Pages: 3592-3598
- DOI
  10.3892/or.2016.4635
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K19763, KAKENHI-PROJECT-15H06007, KAKENHI-PROJECT-26870028, KAKENHI-PROJECT-16K10448, KAKENHI-PROJECT-16K19328
[Journal Article] MORPHOLOGICAL ANALYSIS OF THE RESIDUAL RECTAL MUCOSA IN 12 POSTOPERATIVE ULCERATIVE COLITIS PATIENTS2016
- Author(s)
  Morohashi S, Morohashi H, Yoshizawa T, Tanaka M, Mikami T, Kagiya T, Saito T, Hirai H, Haga T, Wu Y, Hakamada K, Kijima H.
- Journal Title
  
  Hirosaki Med. J.
  
  Volume: 67 Pages: 92-101
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26870028
[Journal Article] Clinicopathological significance of gastric poorly differentiated medullary carcinoma.2016
- Author(s)
  Hirai H, Yoshizawa T, Morohashi S, Haga T, Wu Y, Ota R, Takatsuna M, Akasaka H, Hakamada K, Kijima H.
- Journal Title
  
  Biomed Res.
  
  Volume: 37 Pages: 77-84
- NAID
  130005147429
- Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K15011
[Journal Article] Hypoxia is important in F18 FDG accumulation in thecoma fibroma tumors on F18 FDG PET/CT scans.2016
- Author(s)
  Seino H, Ono S, Miura H, Morohashi S, Wu Y, Tsushima F, Takai Y, Kijima H.
- Journal Title
  
  Mol Med Rep.
  
  Volume: 13 Issue: 5 Pages: 3821-3827
- DOI
  10.3892/mmr.2016.5016
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K19763, KAKENHI-PROJECT-26870028
[Journal Article] Phenotypic Characterization of Early Biliary Tract Carcinomas Proposes Two Carcinogenesis Pathways.2016
- Author(s)
  Haga T, Yoshizawa T, Morohashi S, Hirai H, Saito K, Ota R, Takatusna M, Wu Y, Fukuda S, Kijima H.
- Journal Title
  
  Hirosaki Med. J.
  
  Volume: 67 Pages: 28-38
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26870028
[Journal Article] Basic helix-loop-helix transcription factor DEC2 functions as an anti-apoptotic factor during paclitaxel-induced apoptosis in human prostate cancer cells.2016
- Author(s)
  Liu Q, Wu Y, Yoshizawa T, Yan X, Morohashi S, Seino H, Kato Y, Kijima H.
- Journal Title
  
  Int J Mol Med
  
  Volume: 38 Issue: 6 Pages: 1727-1733
- DOI
  10.3892/ijmm.2016.2798
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H06007, KAKENHI-PROJECT-26870028, KAKENHI-PROJECT-16K10448, KAKENHI-PROJECT-15K15011, KAKENHI-PROJECT-15K19763
[Journal Article] Myofibroblast distribution is associated with invasive growth types of colorectal cancer.2016
- Author(s)
  Takatsuna M, Morohashi S, Yoshizawa T, Hirai H, Haga T, Ota R, Saito K, Wu Y, Seino H, Aoyagi Y, Terai S, Kijima H.
- Journal Title
  
  Oncol Rep
  
  Volume: 36 Issue: 6 Pages: 3154-3160
- DOI
  10.3892/or.2016.5202
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H06007, KAKENHI-PROJECT-26293175, KAKENHI-PROJECT-26870028, KAKENHI-PROJECT-16K10448, KAKENHI-PROJECT-15K15011, KAKENHI-PROJECT-15K19763, KAKENHI-PROJECT-16K19328
[Journal Article] Molecular pathology and carcinogenesis of biliary cancer2015
- Author(s)
  Kijima H, Haga T, Wu Y, Seino H, Hakamada K.
- Journal Title
  
  Nihon Rinsho
  
  Volume: Suppl 3 Pages: 449-156
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26870028
[Journal Article] Basic helix-loop-helix transcription factor DEC1 regulates the cisplatin-induced apoptotic pathway of human esophageal cancer cells 2015
- Author(s)
 Seino H
- Journal Title
 
 Biomed. Res.
 
 Volume: 36 Issue: 2 Pages: 89-96
- DOI
 10.2220/biomedres.36.89
- NAID
 130005065284
- ISSN
 0388-6107, 1880-313X
- Language
 English
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
 KAKENHI-PROJECT-24791265, KAKENHI-PROJECT-26870028, KAKENHI-PROJECT-15K08553, KAKENHI-PROJECT-15K19763, KAKENHI-PROJECT-25462889, KAKENHI-PROJECT-25861148
[Journal Article] 診断に苦慮した乳輪部に発生した巨大尖圭コンジローマの1例2015
- Author(s)
  諸橋聡子, 吉澤忠司, 平井秀明, 羽賀敏博, 清野浩子, 呉雲燕, 泉美貴, 鬼島宏
- Journal Title
  
  診断病理
  
  Volume: 32 Pages: 159-163
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26870028
[Journal Article] Involvement of c-Myc in the proliferation of MCF-7 human breast cancer cells induced by bHLH transcription factor DEC2.2015
- Author(s)
  Wu Y
- Journal Title
  
  Int J Mol Med.
  
  Volume: 35 Issue: 3 Pages: 815-20
- DOI
  10.3892/ijmm.2014.2042
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24791265, KAKENHI-PROJECT-25462889, KAKENHI-PROJECT-26870028, KAKENHI-PROJECT-15K08553, KAKENHI-PROJECT-15K19763, KAKENHI-PROJECT-15H06007
[Journal Article] 【進展度に応じた胆嚢癌の治療戦略】進行度から見た胆嚢癌の病理学的特徴2015
- Author(s)
  鬼島宏, 吉澤忠司, 羽賀敏博, 平井秀明, 桜庭伸吾, 岡野健介, 高綱将史, 清野浩子, 呉雲燕, 諸橋聡子
- Journal Title
  
  胆と膵
  
  Volume: 36 Pages: 19-23
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26870028
[Journal Article] Invasive micropapillary carcinoma of the extrahepatic bile duct and its malignant potential.2014
- Author(s)
  Yoshizawa T, Toyoki Y, Hirai H, Haga T, Toba T, Sakuraba S, Okano K, Wu Y, Seino H, Morohashi S, Hakamada K, Kijima H.
- Journal Title
  
  Oncology Reports
  
  Volume: 32 Issue: 4 Pages: 1355-61
- DOI
  10.3892/or.2014.3394
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24591990, KAKENHI-PROJECT-26870028
[Journal Article] Incidental prostate 18F-FDG uptake without calcification indicates the possibility of prostate cancer.2014
- Author(s)
  Seino H, Ono S, Miura H, Morohashi S, Wu Y, Tsushima F, Takai Y, Kijima H.
- Journal Title
  
  Oncol Rep.
  
  Volume: 31 Issue: 4 Pages: 1517-1522
- DOI
  10.3892/or.2014.3011
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23590386, KAKENHI-PROJECT-24791265, KAKENHI-PROJECT-26870028
[Journal Article] Pathological characteristics of early to advanced gallbladder carcinoma and extrahepatic cholangiocarcinoma.2014
- Author(s)
  Kijima H, Wu Y, Yosizawa T, Suzuki T, Tsugeno Y, Haga T, Seino H, Morohashi S, Hakamada K.
- Journal Title
  
  J Hepatobiliary Pancreat Sci.
  
  Volume: 21 Issue: 7 Pages: 453-8
- DOI
  10.1002/jhbp.72
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23590386, KAKENHI-PROJECT-24591990, KAKENHI-PROJECT-24791265, KAKENHI-PROJECT-25861148, KAKENHI-PROJECT-26870028
[Patent] 細胞培養の上清浄化・濃縮法およびその製造物2020
- Inventor(s)
  吉村浩太郎、齋藤夏美、白土たか子、Wu Yunyan
- Industrial Property Rights Holder
  吉村浩太郎、齋藤夏美、白土たか子、Wu Yunyan
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2020-148193
- Filing Date
  2020
- Data Source
  KAKENHI-PROJECT-20K09850
[Presentation] 浄化濃縮幹細胞培養上清の再生医療への応用展望2020
- Author(s)
  Yunyan Wu, 吉村浩太郎
- Organizer
  第29回日本形成外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-20K09850
[Presentation] Transrational study between pancreatic cancer stroma and clinical image.2019
- Author(s)
  Shintaro Goto, Tadashi Yoshizawa, Kana Saito, Takuya Shimanaka, Hiroko Seino, Takanobu Akaishi, Toshihiro Haga, Satoko Morohashi, Hiroshi Kijima.
- Organizer
  Hirosaki Medical Science Forum 2019.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04057
[Presentation] Microenvironment of Pancreatic Cancer and Clinicopathological Significance.2019
- Author(s)
  Shintaro Goto, Tadashi Yoshizawa, Hiroko Seino, Toshihiro Haga, Satoko Morohashi, Hiroshi Kijima.
- Organizer
  International Conference on Biomedical and Cancer Research. SciTech Biomed-Cancer Sciences 2019.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04057
[Presentation] Correlations between contrast enhanced CT image and histopathological characteristics of the pancreatic cancer stroma.2019
- Author(s)
  Shintaro Goto, Seino Hiroko, Tadashi Yoshizawa, Toshihiro Haga, Satoko Morohashi, Keinosuke Ishido, Kenichi Hakamada, Hiroshi Kijima.
- Organizer
  第16回日本病理学会カンファレンス.
- Data Source
  KAKENHI-PROJECT-17H04057
[Presentation] BHLH transcription factors DEC1 and DEC2: From structure to various diseases.2019
- Author(s)
  Wu Y
- Organizer
  International Conference on Biomedical and Cancer Research
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K17575
[Presentation] DEC1 and DEC2 regulate apoptosis in human prostate cancer cells2018
- Author(s)
  Yunyan Wu, Qiang Liu, Hiroko Seino, Shintaro Goto, Toshihiro Haga, Tadashi Yoshizawa, Hiroshi Kijima
- Organizer
  第107回　日本病理学会総会
- Data Source
  KAKENHI-PROJECT-17K17575
[Presentation] 潰瘍性大腸炎術後の残存直腸粘膜12例の解析(Morphological analysis of the residual rectal mucosa in 12 postoperative ulcerative colitis patients)2017
- Author(s)
  諸橋聡子, 田中正則, 吉澤忠司, 清野浩子, 呉雲燕, 鬼島宏
- Organizer
  日本病理学会
- Data Source
  KAKENHI-PROJECT-16K10448
[Presentation] Dedifferentiated liposarcoma of the pancreas: A case report2017
- Author(s)
  Tadashi Yoshizawa, Satoko Morohashi, Toshihiro Haga, Hiroko Seino, Yunyan Wu, Hiroshi Kijima
- Organizer
  第106回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-17K17575
[Presentation] Morphological analysis of the residual rectal mucosa in 12 postoperative ulcerative colitis patients2017
- Author(s)
  Satoko Morohashi, Masanori Tanaka, Tadashi Yoshizawa, Hiroko Seino, Yunyan Wu, Hiroshi Kijima
- Organizer
  第106回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-17K17575
[Presentation] DEC1 negatively regulates expression of CXCL10 and CCL5 induced by poly IC in human mesangial cells2017
- Author(s)
  Qiang Liu, Tadaatsu Imaizumi, Hiroshi Tanaka, Yunyan Wu, Tadashi Yoshizawa, Satoko Morohashi, Hiroko Seino, Hiroshi Kijima
- Organizer
  第106回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-17K17575
[Presentation] Podoplanin-mediated TGF-β-induced EMT and its correlation with bHLH transcription factor DEC in TE-11 cells.2016
- Author(s)
  Wu Y, Liu Q, Yan X, Kato Y, Yoshizawa T, Seino H, Morohashi S, Kijima H.
- Organizer
  第105回日本病理学会
- Place of Presentation
  仙台国際センター（宮城県・仙台市）
- Year and Date
  2016-05-12
- Data Source
  KAKENHI-PROJECT-26870028
[Presentation] The bHLH transcription factor DEC plays an important role in epithelial-mesenchymal transition (EMT).2016
- Author(s)
  Hiroshi Kijima, Yunyan Wu, Tadashi Yoshizawa, Hiroko Seino, Shintaro Goto, Toshihiro Haga, Satoko Morohashi.
- Organizer
  21st World Congress on Advances in Oncology and 19th International Symposium on Molecular Medicine.
- Place of Presentation
  Athens, (Greece)
- Year and Date
  2016-10-06
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15011
[Presentation] TGF-β-induced podoplanin expression is associated with EMT of human esophageal carcinoma TE-11 cells.2016
- Author(s)
  Wu Y, Liu Q, Yan X, Kato Y, Seino H, Morohashi S, Kijima H.
- Organizer
  第75回日本癌学会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-26870028
[Presentation] TGF-β induced epithelial-mesenchymal transition via podoplanin in human esophageal carcinoma TE-11 cells.2016
- Author(s)
  Wu Y, Liu Q, Yan X, Kato Y, Seino H, Morohashi S, Kijima H.
- Organizer
  第13回日本病理学会カンファレンス
- Place of Presentation
  六甲山ホテル（兵庫県・神戸市）
- Year and Date
  2016-07-29
- Data Source
  KAKENHI-PROJECT-26870028
[Presentation] BHLH transcription factor DEC1 promotes hypoxia-induced EMT of HepG2 cells.2016
- Author(s)
  Keishu Murakami, Yunyan Wu, Yuka Aoki, Hiroko Seino, Satoko Morohashi, Tadaatsu Imaizumi, Hiroshi Kijima.
- Organizer
  21st World Congress on Advances in Oncology and 19th International Symposium on Molecular Medicine.
- Place of Presentation
  Athens, (Greece)
- Year and Date
  2016-10-06
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15011
[Presentation] DEC1 induced by E2-ERα signaling promotes the EMT process of breast cancer cells2015
- Author(s)
  Yunyan Wu, Qiang Liu, Hideaki Hirai, Tadashi Yoshizawa, Satoko Morohashi, Yukio Kato, Hiroshi Kijima
- Organizer
  第104回日本病理学会総会
- Place of Presentation
  名古屋国際会議場　（愛知県・名古屋市）
- Year and Date
  2015-05-01
- Data Source
  KAKENHI-PROJECT-26870028
[Presentation] Involvement of c-Myc in DEC2-induced cell proliferation of breast cancer MCF-7 cells.2014
- Author(s)
  Yunyan Wu, Hidenobu Sato, Keishu Murakami, Hideaki Hirai, Tadashi Yoshizawa, Hiroko Seino, Satoko Morohashi, Yukio Kato, Hiroshi Kijima
- Organizer
  第103回日本病理学会総会
- Place of Presentation
  広島国際会場
- Year and Date
  2014-04-26
- Data Source
  KAKENHI-PROJECT-26870028

1. KIJIMA Hiroshi (90204859)

# of Collaborated Projects: 4 results

# of Collaborated Products: 24 results
2. Morohashi Satoko (90569592)

# of Collaborated Projects: 2 results

# of Collaborated Products: 15 results
3. Seino Hiroko (30598727)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
4. 後藤慎太郎 (00826901)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
5. 吉澤忠司 (70761071)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
6. 袴田健一 (30271802)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
7. 猪口貞樹 (60160008)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 下田浩 (20274748)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 吉村浩太郎 (60210762)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
10. TOYOKI Yoshikazu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. TANAKA Hiroshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 今泉忠淳

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 中澤満

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 大山力

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 古家琢也

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 米山徹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Go Unen 呉 雲燕

Wu Yunyan 呉 雲燕

Research Projects

Research Products

Co-Researchers

エクソソームフリー脂肪幹細胞セクレトーム（EFSE）による再生療法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

A method for detoxifying and concentrating the mesenchmal stem cells' conditioned media and its application in regenerative medicinePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Breast cancer microenvironment control targeting clock gene and its development of MRI imaging

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Functional analysis of clock genes in invasive breast carcinomaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Pathophysiological modulation of high-grade malignant potentials of pancreato-biliary cancer, and its clinical application

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Breast cancer microenvironment control targeting clock gene and its clinical application

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Functional analysis of "angio-lymphatic vessels" in the neoplastic lesions - its histopathological significance

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Functional analysis of clock genes in regulating the microenvironment of breast cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Purification and characterization of human adipose-resident microvascular endothelial progenitor cells2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Adipose-Derived Stem Cell Conditioned Medium and Wound Healing: A Systematic Review2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Time density curve of dynamic contrast enhanced computed tomography correlates with histological characteristics of pancreatic cancer2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Sodium Alginate as a Potential Therapeutic Filler: An In Vivo Study in Rats2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Type I Collagen Induces DEC Expression and Epithelial-Mesenchymal Transition (EMT) in Human Breast Cancer MCF-7 Cells.2019

Author(s)

Journal Title

Data Source

[Journal Article] Histopathological Characteristics of Pancreatic Cancer Stroma Induced by Neoadjuvant Chemotherapy2019

Author(s)

Journal Title

Go Unen 呉雲燕

Wu Yunyan 呉雲燕