OOGA Masatoshi 大我政敏

Researcher Number	40644886
Other IDs
Affiliation (Current)	2025: 麻布大学, 獣医学部, 講師 2025: 山梨大学, 大学院総合研究部, 助教
Affiliation (based on the past Project Information) *help	2022 – 2024: 麻布大学, 獣医学部, 講師 2018 – 2021: 山梨大学, 大学院総合研究部, 助教 2017 – 2018: 山梨大学, 大学院総合研究部, 特任助教 2016: 山梨大学, 総合研究部, 特任助教
Review Section/Research Field	Principal Investigator Basic Section 42030:Animal life science-related / Medium-sized Section 42:Veterinary medical science, animal science, and related fields / Integrative animal science Except Principal Investigator Basic Section 42030:Animal life science-related / Integrative animal science
Keywords	Principal Investigator エピゲノム / 円形精子細胞注入 / 個体形成能 / 代謝記憶 / 着床前初期胚 / 円形精子細胞注入胚 / エピゲノム異常 / 円形精子細胞 / 低産仔率改善 / 低個体形成能 … More / 雌雄差 / ROSI胚 / クロマチン構造 / ROSI … More Except Principal Investigator 栄養 / 発生分化 / 分化 / 発生 / メタボローム / エピゲノム / 生殖科学 / 生殖細胞 / 代謝 / エピジェネティクス / 精子形成 / 染色体 / 核移植絶滅動物 / 卵子 / 顕微授精 / 絶滅動物 / 絶滅危惧種 / 精子 / 凍結乾燥 / 遺伝子資源 / 核移植 / クローン Less

受精後たった1日の間に生じるエピジェネティックな記憶の次世代への継承Principal Investigator
- Principal Investigator
  
  大我政敏
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 42:Veterinary medical science, animal science, and related fields
- Research Institution
  Azabu University
Improving Developmental Potential of ROSI-derived Zygotes via Elimination of Inherited Epigenome from Round SpermatidsPrincipal Investigator
- Principal Investigator
  
  大我政敏
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 42030:Animal life science-related
- Research Institution
  Azabu University
Interplay between epigenetics and metabolism in transgenerational inheritance
- Principal Investigator
  
  Maezawa So
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 42030:Animal life science-related
- Research Institution
  Tokyo University of Science
Identification the cause of and improvement of the low developmental potential of ROSI-derived zygotesPrincipal Investigator
- Principal Investigator
  
  Ooga Masatoshi
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 42030:Animal life science-related
- Research Institution
  University of Yamanashi
Development of the evaluation method and elucidation of molecular basis of zygotic totipotencyPrincipal Investigator
- Principal Investigator
  
  OOGA Masatoshi
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Integrative animal science
- Research Institution
  University of Yamanashi
Feasibility Study for the generation of live cell from extinct or endangered animal
- Principal Investigator
  
  WAKAYAMA Teruhiko
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Integrative animal science
- Research Institution
  University of Yamanashi

All 2024 2023 2020 2019 2018 2017

All Journal Article Presentation

[Journal Article] Chromatin structure in totipotent mouse early preimplantation embryos2024
- Author(s)
  Masatoshi OOGA
- Journal Title
  
  J. Reprod. Dev.
  
  Volume: 70 Issue: 3 Pages: 152-159
- DOI
  10.1262/jrd.2023-106
- ISSN
  0916-8818, 1348-4400
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22H04925, KAKENHI-PROJECT-23K27091
[Journal Article] Polycomb protein SCML2 mediates paternal epigenetic inheritance through sperm chromatin2023
- Author(s)
  Sakashita Akihiko、Ooga Masatoshi、Otsuka Kai、Maezawa So、Takeuchi Chikara、Wakayama Sayaka、Wakayama Teruhiko、Namekawa Satoshi?H
- Journal Title
  
  Nucleic Acids Research
  
  Volume: 51 Issue: 13 Pages: 6668-6683
- DOI
  10.1093/nar/gkad479
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K18084, KAKENHI-PUBLICLY-22H04700, KAKENHI-PROJECT-21H02383
[Journal Article] Polycomb protein SCML2 mediates paternal epigenetic inheritance through sperm chromatin2023
- Author(s)
  *Sakashita A, Ooga M, Otsuka K, Maezawa S, Takeuchi C, Wakayama S, Wakayama T, and *Namekawa SH
- Journal Title
  
  Nucleic Acids Research
  
  Volume: in press
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02383
[Journal Article] Aberrant histone methylation in mouse early preimplantation embryos derived from round spermatid injection2023
- Author(s)
  Ooga Masatoshi、Kikuchi Yasuyuki、Ito Daiyu、Kazama Kousuke、Inoue Rei、Sakamoto Mizuki、Wakayama Sayaka、Wakayama Teruhiko
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 680 Pages: 119-126
- DOI
  10.1016/j.bbrc.2023.09.020
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K27091
[Journal Article] Chd9 mediates highly loosened chromatin structure in growing mouse oocytes2018
- Author(s)
  Ooga Masatoshi、Funaya Satoshi、Hashioka Yuki、Fujii Wataru、Naito Kunihiko、Suzuki Masataka G.、Aoki Fugaku
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 500 Issue: 3 Pages: 583-588
- DOI
  10.1016/j.bbrc.2018.04.105
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K15394, KAKENHI-PROJECT-25252056, KAKENHI-PUBLICLY-16H01215
[Journal Article] Assessing the tolerance to room temperature and viability of freeze-dried mice spermatozoa over long-term storage at room temperature under vacuum2018
- Author(s)
  Kamada Yuko、Wakayama Sayaka、Shibasaki Ikue、Ito Daiyu、Kamimura Satoshi、Ooga Masatoshi、Wakayama Teruhiko
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1 Pages: 10602-10602
- DOI
  10.1038/s41598-018-28896-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H02593
[Journal Article] Zygotic fluorescence recovery after photo-bleaching analysis for chromatin looseness that allows full-term development2018
- Author(s)
  Ooga Masatoshi、Funaya Satoshi、Aoki Fugaku、Wakayama Teruhiko
- Journal Title
  
  Journal of visualized experiments
  
  Volume: ー Issue: 136 Pages: 136-136
- DOI
  10.3791/57068
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K15394, KAKENHI-PROJECT-16H02593
[Journal Article] FRAP analysis of chromatin looseness in mouse zygotes that allows full-term development2017
- Author(s)
  Ooga Masatoshi、Wakayama Teruhiko
- Journal Title
  
  PLOS ONE
  
  Volume: 12 Issue: 5 Pages: e0178255-e0178255
- DOI
  10.1371/journal.pone.0178255
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K15394, KAKENHI-PROJECT-16H02593
[Journal Article] Production of cloned mice using oocytes derived from ICR-outbred strain.2017
- Author(s)
  Tanabe Y, Kuwayama H, Wakayama S, Nagatomo H, Ooga M, Kamimura S, Kishigami S, Wakayama T.
- Journal Title
  
  Reproduction
  
  Volume: 154(6) Issue: 6 Pages: 859-866
- DOI
  10.1530/rep-17-0372
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K15359, KAKENHI-PROJECT-16H02593, KAKENHI-PROJECT-16J07536
[Presentation] マウス受精卵のクロマチン構造における Parental asymmetryの形成機構について2020
- Author(s)
  大我政敏、上村悟氏、若山照彦
- Organizer
  日本生殖発生医学会
- Data Source
  KAKENHI-PROJECT-19K16012
[Presentation] マウス１細胞期胚での緩んだクロマチン構造における雌雄前核間差の形成機構2019
- Author(s)
  大我政敏、上村悟氏、若山照彦
- Organizer
  第１１２回日本繁殖生物学会
- Data Source
  KAKENHI-PROJECT-19K16012
[Presentation] マウス１細胞期胚のクロマチン構造の"緩み"におけるParental asymmetryの形成機構について2019
- Author(s)
  大我政敏、上村悟氏、若山照彦
- Organizer
  日本生殖発生医学会第１５回学術大会
- Data Source
  KAKENHI-PROJECT-19K16012
[Presentation] Mechanisms of the establishment for parental asymmetric chromatin structure in mouse zygotes2019
- Author(s)
  Masatoshi Ooga, Satoshi Kamimura and Teruhiko Wakayama
- Organizer
  The second international conference on cell reprogramming and reproductive biotechnology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16012
[Presentation] マウス円形精子細胞注入胚の低産仔率の原因究明と向上の試み2018
- Author(s)
  風間晃輔、大我政敏、上村悟氏、若山照彦
- Organizer
  日本哺乳類卵子学会
- Data Source
  KAKENHI-PROJECT-17K15394
[Presentation] マウス円形精子細胞注入胚の低産仔率の原因究明と向上の試み2018
- Author(s)
  風間晃輔、大我政敏、上村悟氏、若山照彦
- Organizer
  日本卵子学会
- Data Source
  KAKENHI-PROJECT-17K15394
[Presentation] Abnormal chromatin structure in the male pronucleus fertilized with Round spermatid2018
- Author(s)
  Masatoshi Ooga、Teruhiko Wakayama
- Organizer
  Epigenomics Data Analysis Core Presents Seminar
- Invited
- Data Source
  KAKENHI-PROJECT-17K15394
[Presentation] Establishment of zygotic fluorescence recovery after photobleaching for ROSI-derived zygotes2018
- Author(s)
  Masatoshi Ooga, Kousuke Kazama and Teruhiko Wakayama
- Organizer
  The international Conference on Cell Reprogramming and Reproduction
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15394
[Presentation] ROSI胚におけるepigenetic parental asymmetryの消失と回復2018
- Author(s)
  大我政敏、風間晃輔、上村悟氏、若山照彦
- Organizer
  繁殖生物学会
- Data Source
  KAKENHI-PROJECT-17K15394
[Presentation] Production of cloned mice using oocytes derived from ICR strain.2017
- Author(s)
  Yoshiaki Tanabe, Hiroki Kuwayama, Sayaka Wakayama, Hiroaki Nagatomo, Masatoshi Ooga, Satoshi Kamimura, Satoshi Kishigami, and Teruhiko Wakayama
- Organizer
  4th World Congress of Reproductive Biology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02593
[Presentation] Developmental competence of mouse oocytes activated by injection of PLCζ from different species2017
- Author(s)
  Yunosuke Yamamoto, Masatoshi Ooga, Satoshi Kamimura, Hiroaki Nagatomo, Sayaka Wakayama, Junya Ito, and Teruhiko Wakayama
- Organizer
  4th World Congress of Reproductive Biology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02593
[Presentation] Improvement of freeze-drying preservation method of spermatozoa at room temperature.2017
- Author(s)
  Yuko Kamada, Daiyu Ito, Ikue Shibasaki, Satoshi Kamimura, Hiroaki Nagatomo, Masatoshi Ooga, Sayaka Wakayama and Teruhiko Wakayama
- Organizer
  4th World Congress of Reproductive Biology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02593
[Presentation] Disrupted parental asymmetry of chromatin structure in ROSI-derived zygotes.2017
- Author(s)
  Masatoshi Ooga, and Teruhiko Wakayama
- Organizer
  4th World Congress of Reproductive Biology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02593
[Presentation] Disrupted parental asymmetry of chromatin structure in ROSI-derived zygotes2017
- Author(s)
  Masatoshi Ooga、Kousuke Kazama、 Satoshi Kamimura、Teruhiko Wakayama
- Organizer
  World congress of reproductive biology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15394
[Presentation] Unique method for producing oocyte that decreased spindle formation factors2017
- Author(s)
  Shunsuke Konno, Masatoshi Ooga, Satoshi Kamimura, Sayaka Wakayama and Teruhiko Wakayama
- Organizer
  4th World Congress of Reproductive Biology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02593

1. WAKAYAMA Teruhiko (40360672)

# of Collaborated Projects: 2 results

# of Collaborated Products: 14 results
2. 林陽平 (00588056)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. Maezawa So (90548174)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
4. 岸上哲士 (10291064)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. 長友啓明 (30746813)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
6. 水谷英二 (80443034)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. WAKAYAMA Sayaka

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results

OOGA Masatoshi 大我 政敏

Research Projects

Research Products

Co-Researchers

受精後たった1日の間に生じるエピジェネティックな記憶の次世代への継承Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Improving Developmental Potential of ROSI-derived Zygotes via Elimination of Inherited Epigenome from Round SpermatidsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Interplay between epigenetics and metabolism in transgenerational inheritance

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification the cause of and improvement of the low developmental potential of ROSI-derived zygotesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of the evaluation method and elucidation of molecular basis of zygotic totipotencyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Feasibility Study for the generation of live cell from extinct or endangered animal

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Chromatin structure in totipotent mouse early preimplantation embryos2024

Author(s)

Journal Title

DOI

ISSN

Language

Data Source

[Journal Article] Polycomb protein SCML2 mediates paternal epigenetic inheritance through sperm chromatin2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Polycomb protein SCML2 mediates paternal epigenetic inheritance through sperm chromatin2023

Author(s)

Journal Title

Data Source

[Journal Article] Aberrant histone methylation in mouse early preimplantation embryos derived from round spermatid injection2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Chd9 mediates highly loosened chromatin structure in growing mouse oocytes2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Assessing the tolerance to room temperature and viability of freeze-dried mice spermatozoa over long-term storage at room temperature under vacuum2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Zygotic fluorescence recovery after photo-bleaching analysis for chromatin looseness that allows full-term development2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] FRAP analysis of chromatin looseness in mouse zygotes that allows full-term development2017

Author(s)

Journal Title

DOI

OOGA Masatoshi 大我政敏