Tanaka Yoko 田中陽子

Researcher Number	40647434
Other IDs
Affiliation (Current)	2026: 公益財団法人がん研究会, がん研究所細胞老化研究部, 特任研究員
Affiliation (based on the past Project Information) *help	2026: 公益財団法人がん研究会, がん研究所細胞老化研究部, 特任研究員 2022 – 2024: 公益財団法人がん研究会, がん研究所細胞老化研究部, 特任研究員 2018: 公益財団法人がん研究会, がん研究所細胞老化プロジェクト, 研究員 2017: 東京医科歯科大学, 医歯(薬)学総合研究科, 特任助教 2016: 東京医科歯科大学, 大学院医歯学総合研究科, 日本学術振興会特別研究員
Review Section/Research Field	Principal Investigator Basic Section 50010:Tumor biology-related / Orthopaedic surgery
Keywords	Principal Investigator SASP / CAF / 膵臓がん / 老化細胞 / 糖鎖 / がん微小環境 / 細胞外小胞 / エクソソーム / 細胞老化 / 核酸 … More / 発現制御 / 細胞・組織 / 次世代シークエンシング / 滑膜 / 滑膜細胞 / 関節リウマチ / NGS / A-to-I RNA editing / microRNA / synovium / rheumatoid arthritis Less

加齢が膵臓がんの腫瘍微小環境に与える影響の解明Principal Investigator
- Principal Investigator
  
  田中陽子
- Project Period (FY)
  2026 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Japanese Foundation for Cancer Research
The role of exosomes secreted from senescent cells in cancer pathologyPrincipal Investigator
- Principal Investigator
  
  Tanaka Yoko
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Japanese Foundation for Cancer Research
The function of microRNA cluster on 14 chromosome of synoviumPrincipal Investigator
- Principal Investigator
  
  Tanaka Yoko
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Japanese Foundation for Cancer Research
  Tokyo Medical and Dental University

All 2024 2023 2022 2017 2016

All Journal Article Presentation

[Journal Article] Nanoparticles Based on Natural Lipids Reveal Extent of Impacts of Designed Physical Characteristics on Biological Functions2024
- Author(s)
  Kimura Niko、Tanaka Yoko、Yamanishi Yoko、Takahashi Akiko、Sakuma Shinya
- Journal Title
  
  ACS Nano
  
  Volume: 18 Issue: 2 Pages: 1432-1448
- DOI
  10.1021/acsnano.3c07461
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K07222
[Journal Article] <scp>D</scp>ipeptidylpeptidase‐4‐targeted activatable fluorescent probes visualize senescent cells2024
- Author(s)
  Tanaka Hisamichi、Sugawara Sho、Tanaka Yoko、Loo Tze Mun、Tachibana Ryo、Abe Atsuki、Kamiya Mako、Urano Yasuteru、Takahashi Akiko
- Journal Title
  
  Cancer Science
  
  Volume: 115 Issue: 8 Pages: 2762-2773
- DOI
  10.1111/cas.16229
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24H00050, KAKENHI-PROJECT-23K23460, KAKENHI-PROJECT-23K24168, KAKENHI-PROJECT-22K07222
[Journal Article] Network of extracellular vesicles surrounding senescent cells2024
- Author(s)
  Okawa Hikaru、Tanaka Yoko、Takahashi Akiko
- Journal Title
  
  Archives of Biochemistry and Biophysics
  
  Volume: 754 Pages: 109953-109953
- DOI
  10.1016/j.abb.2024.109953
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K07222
[Journal Article] The Rubicon-WIPI axis regulates exosome biogenesis during ageing2024
- Author(s)
  Yanagawa K, Kuma A, Hamasaki M, Kita S, Yamamuro T, Nishino K, Nakamura S, Omori H, Kaminishi T, Oikawa S, Kato Y, Edahiro R, Kawagoe R, Taniguchi T, Tanaka Y, Shima T, Tabata K, Iwatani M, Bekku N, Hanayama R, Okada Y, Akimoto T, Kosako H, Takahashi A, Shimomura I, Sakata Y, Yoshimori T
- Journal Title
  
  Nature Cell Biology
  
  Volume: 26 Issue: 9 Pages: 1558-1570
- DOI
  10.1038/s41556-024-01481-0
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22H04982, KAKENHI-PROJECT-21K06169, KAKENHI-PROJECT-22K07222, KAKENHI-PROJECT-22K08669, KAKENHI-PROJECT-23K18140, KAKENHI-PROJECT-22KJ2105, KAKENHI-PROJECT-24K18072, KAKENHI-PROJECT-22KK0153
[Journal Article] YBX1 Regulates Satellite II RNA Loading into Small Extracellular Vesicles and Promotes the Senescent Phenotype2023
- Author(s)
  Chiba Masatomo、Miyata Kenichi、Okawa Hikaru、Tanaka Yoko、Ueda Koji、Seimiya Hiroyuki、Takahashi Akiko
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 24 Issue: 22 Pages: 16399-16399
- DOI
  10.3390/ijms242216399
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K18247, KAKENHI-PROJECT-22K07222, KAKENHI-PROJECT-22K19469, KAKENHI-PROJECT-23KJ0554, KAKENHI-PROJECT-23K24168, KAKENHI-PROJECT-23K24192
[Journal Article] 老化細胞が分泌するSASP因子による細胞競合阻害作用2023
- Author(s)
  千葉正智、田中陽子、高橋暁子
- Journal Title
  
  生化学
  
  Volume: 95 Pages: 336-340
- Open Access
- Data Source
  KAKENHI-PROJECT-22K07222
[Journal Article] Identification of Novel Senescent Markers in Small Extracellular Vesicles2023
- Author(s)
  Misawa Tomoka、Hitomi Kazuhiro、Miyata Kenichi、Tanaka Yoko、Fujii Risa、Chiba Masatomo、Loo Tze Mun、Hanyu Aki、Kawasaki Hiroko、Kato Hisaya、Maezawa Yoshiro、Yokote Koutaro、Nakamura Asako J.、Ueda Koji、Yaegashi Nobuo、Takahashi Akiko
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 24 Issue: 3 Pages: 2421-2421
- DOI
  10.3390/ijms24032421
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07222, KAKENHI-PROJECT-22K15682, KAKENHI-PROJECT-20H03572, KAKENHI-PROJECT-22KJ0248, KAKENHI-PROJECT-20K16344
[Journal Article] 老化細胞由来のエクソソームの機能2022
- Author(s)
  田中陽子、高橋暁子
- Journal Title
  
  Clinical Neuroscience
  
  Volume: 40(7) Pages: 845-847
- Data Source
  KAKENHI-PROJECT-22K07222
[Journal Article] microRNAと疾患2017
- Author(s)
  三ツ村隆弘、田中陽子、浅原弘嗣
- Journal Title
  
  Clinical Immunology & Allergology
  
  Volume: 67(6) Pages: 629-635
- NAID
  40021232409
- Data Source
  KAKENHI-PROJECT-16K20038
[Presentation] Satellite Ⅱ RNA Regulates Transcription of Inflammatory Gene Expression in Recipient Cells through Small Extracellular Vesicles2024
- Author(s)
  Yoko Tanaka, Masatomo Chiba, Hikaru Okawa, Akiko Takahashi
- Organizer
  Project CHANGE 3rd General Meeting
- Data Source
  KAKENHI-PROJECT-22K07222
[Presentation] Satellite Ⅱ RNA is Transported into Small Extracellular Vesicles by YBX1 and Propagates Senescent Phenotypes2024
- Author(s)
  Yoko Tanaka, Masatomo Chiba, Hikaru Okawa, Akiko Takahashi
- Organizer
  A3 Foresight Program: Joint kick-off meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K07222
[Presentation] 細胞外小胞を用いた新規細胞老化マーカーの同定2022
- Author(s)
  三澤知香、人見一寛、宮田憲一、田中陽子、千葉正智、羅智文、川崎裕子、植田幸嗣、加藤尚也、前澤喜朗、横手幸太郎、八重樫伸生、高橋暁子
- Organizer
  日本細胞外小胞学会
- Data Source
  KAKENHI-PROJECT-22K07222
[Presentation] microRNA-381による関節炎制御と新規レポーターライブラリーシステムを用いたターゲット遺伝子の特定2017
- Author(s)
  田中陽子、高田修治、宮澤慎一、古松毅之、西田圭一郎、浅原弘嗣
- Organizer
  第4回日本リウマチ学会ベーシックリサーチカンファレンス
- Data Source
  KAKENHI-PROJECT-16K20038
[Presentation] microRNA-381のA-to-I RNA editingによる関節炎制御メカニズムの解明2017
- Author(s)
  田中陽子、高田修治、飯笹久、Artemis Hatzigeorgiou、宮澤慎一、古松毅之、西田圭一郎、浅原弘嗣
- Organizer
  第40回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-16K20038
[Presentation] MicroRNA-381 mimic resulted in a therapeutic effect on arthritis by controlling several functions of fibroblast-like synoviocytes2016
- Author(s)
  Yoko Tanaka-Watanabe, Shuji Takada, Shin-ichi Miyazawa, Takauki Furumatsu, Keiichiro Nishida, Hiroshi Asahara
- Organizer
  Cold Spring Harbor Asia conference on Bone & Cartilage: From Development to Human Diseases
- Place of Presentation
  Suzhou (China)
- Year and Date
  2016-10-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K20038
[Presentation] 関節炎におけるmicroRNA-381の機能解明2016
- Author(s)
  田中陽子、高田修治、飯笹久、Artemis Hatzigeorgiou、宮澤慎一、古松毅之、西田圭一郎、淺原弘嗣
- Organizer
  第38回日本分子生物学会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-16K20038
[Presentation] A to I RNA editing of microRNA-381 dysregulates proliferation of fibroblast-like synoviocytes2016
- Author(s)
  Yoko Tanaka-Watanabe, Shuji Takada, Hiroshi Asahara
- Organizer
  Cell Symposia: Functional RNAs
- Place of Presentation
  Guangzhou (China)
- Year and Date
  2016-11-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K20038
[Presentation] MicroRNA-381 ameliorates arthritis by controlling functions of fibroblast-like synoviocytes, which are affected by A to I RNA editing2016
- Author(s)
  Yoko Tanaka-Watanabe, Shuji Takada, Iizasa Hisashi, Artemis Hatzigeorgiou, Shin-ichi Miyazawa, Takayuki Furumatsu, Keiichiro Nishida, Hiroshi Asahara
- Organizer
  Annual European Congress of Rheumatology 2016
- Place of Presentation
  London (UK)
- Year and Date
  2016-06-08
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K20038
[Presentation] microRNA-381による関節炎の制御2016
- Author(s)
  田中陽子, 高田修治, 宮澤慎一, 古松毅之, 西田圭一郎, 淺原弘嗣
- Organizer
  第3回日本リウマチ学会ベーシックカンファレンス
- Place of Presentation
  アキバホール（東京千代田区）
- Year and Date
  2016-10-14
- Data Source
  KAKENHI-PROJECT-16K20038

1. 宮田憲一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. 浦野泰照

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 神谷真子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 吉森保

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 中村修平

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Tanaka Yoko 田中 陽子

Research Projects

Research Products

Co-Researchers

加齢が膵臓がんの腫瘍微小環境に与える影響の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The role of exosomes secreted from senescent cells in cancer pathologyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The function of microRNA cluster on 14 chromosome of synoviumPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Nanoparticles Based on Natural Lipids Reveal Extent of Impacts of Designed Physical Characteristics on Biological Functions2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] <scp>D</scp>ipeptidylpeptidase‐4‐targeted activatable fluorescent probes visualize senescent cells2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Network of extracellular vesicles surrounding senescent cells2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The Rubicon-WIPI axis regulates exosome biogenesis during ageing2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] YBX1 Regulates Satellite II RNA Loading into Small Extracellular Vesicles and Promotes the Senescent Phenotype2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 老化細胞が分泌するSASP因子による細胞競合阻害作用2023

Author(s)

Journal Title

Data Source

[Journal Article] Identification of Novel Senescent Markers in Small Extracellular Vesicles2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 老化細胞由来のエクソソームの機能2022

Author(s)

Journal Title

Data Source

[Journal Article] microRNAと疾患2017

Author(s)

Journal Title

NAID

Data Source

[Presentation] Satellite Ⅱ RNA Regulates Transcription of Inflammatory Gene Expression in Recipient Cells through Small Extracellular Vesicles2024

Author(s)

Organizer

Data Source

[Presentation] Satellite Ⅱ RNA is Transported into Small Extracellular Vesicles by YBX1 and Propagates Senescent Phenotypes2024

Author(s)

Organizer

Data Source

[Presentation] 細胞外小胞を用いた新規細胞老化マーカーの同定2022

Author(s)

Organizer

Data Source

[Presentation] microRNA-381による関節炎制御と新規レポーターライブラリーシステムを用いたターゲット遺伝子の特定2017

Author(s)

Organizer

Tanaka Yoko 田中陽子