Hashimoto Yusuke 橋本佑輔

Researcher Number	40649381
Other IDs
Affiliation (Current)	2026: 群馬大学, 大学院医学系研究科, 助教
Affiliation (based on the past Project Information) *help	2026: 群馬大学, 大学院医学系研究科, 助教 2019 – 2024: 群馬大学, 大学院医学系研究科, 助教
Review Section/Research Field	Principal Investigator Basic Section 54030:Infectious disease medicine-related / Basic Section 49050:Bacteriology-related
Keywords	Principal Investigator バンコマイシン耐性 / バンコマイシン / 腸球菌 / プラスミド / 薬剤耐性 / fitness cost / キノロン耐性遺伝子 / キノロン耐性 / 接合伝達 / AMR … More / 病原性 / 発現メカニズム / バンコマイシン耐性腸球菌 / 線状プラスミド / 二成分制御系 Less

キメラ線状プラスミドが媒介する動物・環境から医療関連腸球菌への遺伝子流動機構Principal Investigator
- Principal Investigator
  
  橋本佑輔
- Project Period (FY)
  2026 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49050:Bacteriology-related
- Research Institution
  Gunma University
Epidemiological analysis of novel linear plasmids in Enterococcus faecium, and elucidation of the mechanisms of acquisition and transmission of antimicrobial resistance genes.Principal Investigator
- Principal Investigator
  
  Hashimoto Yusuke
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 54030:Infectious disease medicine-related
- Research Institution
  Gunma University
Analysis of a new mechanism of resistance gene expression in vancomycin-resistant enterococciPrincipal Investigator
- Principal Investigator
  
  Hashimoto Yusuke
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 54030:Infectious disease medicine-related
- Research Institution
  Gunma University

All 2024 2023 2022 2021 2020 2019

All Journal Article Presentation

[Journal Article] Na+-V-ATPase inhibitor curbs VRE growth and unveils Na+ pathway structure2024
- Author(s)
  Suzuki K.、Goto Y.、Otomo A.、Shimizu K.、Abe S.、Moriyama K.、Yasuda S.、Hashimoto Y.、Kurushima J.、Mikuriya S.、Imai F. L.、Adachi N.、Kawasaki M.、Sato Y.、Ogasawara S.、Iwata S.、Senda T.、Ikeguchi M.、Tomita H.、Iino R.、Moriya T.、Murata T.
- Journal Title
  
  Nature Structural & Molecular Biology
  
  Volume: 32 Issue: 3 Pages: 450-458
- DOI
  10.1038/s41594-024-01419-y
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24H00550, KAKENHI-PROJECT-22K05089, KAKENHI-PROJECT-22K07067, KAKENHI-PROJECT-23K18285, KAKENHI-PROJECT-22K16368, KAKENHI-PROJECT-24K01996, KAKENHI-PROJECT-22K07052, KAKENHI-PROJECT-23KF0133
[Journal Article] The emergence of metronidazole-resistant <i>Prevotella bivia</i> harboring <i>nimK</i> gene in Japan2024
- Author(s)
  Ito Yukitaka、Hashimoto Yusuke、Suzuki Masato、Kaneko Naomi、Yoshida Mieko、Nakayama Haruo、Tomita Haruyoshi
- Journal Title
  
  Microbiology Spectrum
  
  Volume: 12 Issue: 10
- DOI
  10.1128/spectrum.00562-24
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K07067, KAKENHI-PROJECT-22K16368, KAKENHI-PROJECT-23K06556
[Journal Article] Enterococcal Linear Plasmids Adapt to Enterococcus faecium and Spread within Multidrug-Resistant Clades2023
- Author(s)
  Hashimoto Yusuke、Suzuki Masato、Kobayashi Sae、Hirahara Yuki、Kurushima Jun、Hirakawa Hidetada、Nomura Takahiro、Tanimoto Koichi、Tomita Haruyoshi
- Journal Title
  
  Antimicrobial Agents and Chemotherapy
  
  Volume: 67 Issue: 4 Pages: 67-67
- DOI
  10.1128/aac.01619-22
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K16368, KAKENHI-PROJECT-20K07509, KAKENHI-PROJECT-22K07052, KAKENHI-PROJECT-22K07067, KAKENHI-PROJECT-23K06556
[Journal Article] Elucidation of host diversity of the VanD-carrying genomic islands in enterococci and anaerobes2022
- Author(s)
  Hashimoto Yusuke、Hisatsune Junzo、Suzuki Masato、Kurushima Jun、Nomura Takahiro、Hirakawa Hidetada、Kojima Naoko、Ono Yuichi、Hasegawa Yutaka、Tanimoto Koichi、Sugai Motoyuki、Tomita Haruyoshi
- Journal Title
  
  JAC-Antimicrobial Resistance
  
  Volume: 4 Issue: 1 Pages: 189-189
- DOI
  10.1093/jacamr/dlab189
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07533, KAKENHI-PROJECT-19K17922, KAKENHI-PROJECT-20K07509
[Journal Article] First Report of the Local Spread of Vancomycin-Resistant Enterococci Ascribed to the Interspecies Transmission of a vanA Gene Cluster-Carrying Linear Plasmid2020
- Author(s)
  Hashimoto Yusuke、Kita Izumi、Suzuki Masato、Hirakawa Hidetada、Ohtaki Hirofumi、Tomita Haruyoshi
- Journal Title
  
  mSphere
  
  Volume: 5 Issue: 2
- DOI
  10.1128/msphere.00102-20
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08846, KAKENHI-PROJECT-20K07509, KAKENHI-PROJECT-19K17922, KAKENHI-PROJECT-18K07101
[Journal Article] Novel multidrug-resistant enterococcal mobile linear plasmid pELF1 encoding vanA and vanM gene clusters from a Japanese vancomycin-resistant enterococci isolate2019
- Author(s)
  Hashimoto Y, Taniguchi M, Uesaka K, Nomura T, Hirakawa H, Tanimoto K, Tamai K, Ruan G, Zheng B, Tomita H.
- Journal Title
  
  Front Microbiol
  
  Volume: 10 Pages: 2568-2568
- DOI
  10.3389/fmicb.2019.02568
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07101, KAKENHI-PROJECT-19K17922
[Presentation] 腸球菌のpELF型線状プラスミドと薬剤耐性遺伝子2024
- Author(s)
  橋本佑輔
- Organizer
  第97回日本細菌学会総会シンポジウムS1
- Data Source
  KAKENHI-PROJECT-22K16368
[Presentation] Tracing the emergence of a novel fluoroquinolone resistance gene in enterococci through environmental reservoirs and pELF-type linear plasmids.2024
- Author(s)
  Yusuke Hashimoto, Masato Suzuki, Trung Duc Dao, Ikuro Kasuga,Taichiro Takemura, Haruka Abe, Futoshi Hasebe, Yusuke Tsuda, Takahiro Nomura, Jun Kurushima, Hidetada Hirakawa, Koichi Tanimoto, Keigo Shibayama, Hoang H. Tran, Michael S. Gilmore, Haruyoshi Tomita
- Organizer
  International Symposium on Plasmid Biology 2024
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K16368
[Presentation] Enterococcal linear plasmids adapt to Enterococcus faecium and spread within multidrug-resistant clades.2023
- Author(s)
  橋本　佑輔
- Organizer
  第53回レンサ球菌研究会
- Data Source
  KAKENHI-PROJECT-22K16368
[Presentation] Enterococcal linear plasmids adapt to Enterococcus faecium and spread within multidrug-resistant clades.2023
- Author(s)
  ○橋本佑輔、鈴木仁人、野村隆浩、久留島潤、平川秀忠、谷本弘一、富田治芳
- Organizer
  第96回日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-22K16368
[Presentation] Analysis of a novel drug resistance determinant and epidemiology of pELF1-type linear plasmid associated with multidrug resistance in vancomycin-resistant enterococci detected isolated in a metropolitan aquatic environment in Vietnam2023
- Author(s)
  橋本　佑輔
- Organizer
  第6回国際腸球菌学会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K16368
[Presentation] 腸球菌のpELF1型線状プラスミドと新規薬剤排出ポンプ遺伝子2023
- Author(s)
  橋本　佑輔
- Organizer
  第52回薬剤耐性菌研究会
- Data Source
  KAKENHI-PROJECT-22K16368
[Presentation] 腸球菌のpELF1型高頻度接合伝達性プラスミドの研究2022
- Author(s)
  ○橋本佑輔、鈴木仁人、野村隆浩、久留島潤、平川秀忠、谷本弘一、富田治芳
- Organizer
  微生物コンソーシアム G3 第14回定例会
- Data Source
  KAKENHI-PROJECT-22K16368
[Presentation] Enterococcal linear plasmids adapt to Enterococcus faecium and spread within multidrug-resistant clades.2022
- Author(s)
  ○橋本佑輔、鈴木仁人、野村隆浩、久留島潤、平川秀忠、谷本弘一、富田治芳
- Organizer
  第51回薬剤耐性菌研究会
- Data Source
  KAKENHI-PROJECT-22K16368
[Presentation] 腸球菌のpELF1型高頻度接合伝達性プラスミドに関する分子疫学解析2022
- Author(s)
  ○富田治芳○、橋本佑輔、鈴木仁人、野村隆浩、久留島潤、平川秀忠、谷本弘一
- Organizer
  第52回レンサ球菌研究会
- Data Source
  KAKENHI-PROJECT-22K16368
[Presentation] 腸球菌の線状プラスミドに関する分子疫学解析2022
- Author(s)
  ○橋本佑輔、鈴木仁人、野村隆浩、久留島潤、平川秀忠、谷本弘一、富田治芳
- Organizer
  第95回日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-19K17922
[Presentation] VanD型バンコマイシン耐性遺伝子群保有genomic islandの宿主多様性に関する分子疫学解析2021
- Author(s)
  橋本佑輔、久恒順三、鈴木仁人、野村隆浩、久留島潤、平川秀忠、谷本弘一、菅井基行、富田治芳
- Organizer
  第50回薬剤耐性菌研究会
- Data Source
  KAKENHI-PROJECT-19K17922
[Presentation] Local Spread of Vancomycin-Resistant Enterococci Ascribed to the Interspecies Transmission of a vanA Gene Cluster-Carrying Linear Plasmid2021
- Author(s)
  橋本佑輔, 鈴木仁人, 野村隆浩, 久留島潤, 平川秀忠, 谷本弘一, 富田治芳
- Organizer
  第94回日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-19K17922
[Presentation] VanD型バンコマイシン耐性遺伝子群保有genomic islandに関する分子疫学解析2021
- Author(s)
  橋本佑輔、久恒順三、鈴木仁人、野村隆浩、久留島潤、平川秀忠、谷本弘一、菅井基行、富田治芳
- Organizer
  第104回日本細菌学会関東支部総会
- Data Source
  KAKENHI-PROJECT-19K17922
[Presentation] 国内医療機関より分離されたVanA型とVanM型の2つのバンコマイシン耐性遺伝子群を保有する腸球菌の線状プラスミドに関する分子生物学的研究2020
- Author(s)
  橋本佑輔、野村隆浩、平川秀忠、谷本弘一、富田治芳
- Organizer
  第93回日本細菌学会総会 (ウインクあいち、愛知県）
- Data Source
  KAKENHI-PROJECT-19K17922
[Presentation] 国内医療機関より分離されたVanA型とVanM型の2つのバンコマイシン耐性遺伝子群を保有する腸球菌の線状プラスミドに関する分子生物学的研究2020
- Author(s)
  橋本佑輔、野村隆浩、谷本弘一、富田治芳
- Organizer
  第31回日本臨床微生物学会総会 (県立音楽堂等、石川県)
- Data Source
  KAKENHI-PROJECT-19K17922
[Presentation] 国内医療機関より分離されたVanA型とVanM型の2つのバンコマイシン耐性遺伝子群を保有するVRE関する分子生物学的研究2019
- Author(s)
  橋本佑輔、平川秀忠、谷本弘一、富田治芳
- Organizer
  第66回日本化学療法学会東日本支部総会（仙台国際センター、宮城県）
- Data Source
  KAKENHI-PROJECT-19K17922

1. MURATA Takeshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. SUZUKI Masato

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 森山克彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 後藤義幸

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 富田治芳

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
6. 平川秀忠

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Hashimoto Yusuke 橋本 佑輔

Research Projects

Research Products

Co-Researchers

キメラ線状プラスミドが媒介する動物・環境から医療関連腸球菌への遺伝子流動機構Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Epidemiological analysis of novel linear plasmids in Enterococcus faecium, and elucidation of the mechanisms of acquisition and transmission of antimicrobial resistance genes.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of a new mechanism of resistance gene expression in vancomycin-resistant enterococciPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Na+-V-ATPase inhibitor curbs VRE growth and unveils Na+ pathway structure2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The emergence of metronidazole-resistant <i>Prevotella bivia</i> harboring <i>nimK</i> gene in Japan2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Enterococcal Linear Plasmids Adapt to Enterococcus faecium and Spread within Multidrug-Resistant Clades2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Elucidation of host diversity of the VanD-carrying genomic islands in enterococci and anaerobes2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] First Report of the Local Spread of Vancomycin-Resistant Enterococci Ascribed to the Interspecies Transmission of a vanA Gene Cluster-Carrying Linear Plasmid2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Novel multidrug-resistant enterococcal mobile linear plasmid pELF1 encoding vanA and vanM gene clusters from a Japanese vancomycin-resistant enterococci isolate2019

Author(s)

Journal Title

DOI

Data Source

[Presentation] 腸球菌のpELF型線状プラスミドと薬剤耐性遺伝子2024

Author(s)

Organizer

Data Source

[Presentation] Tracing the emergence of a novel fluoroquinolone resistance gene in enterococci through environmental reservoirs and pELF-type linear plasmids.2024

Author(s)

Organizer

Data Source

[Presentation] Enterococcal linear plasmids adapt to Enterococcus faecium and spread within multidrug-resistant clades.2023

Author(s)

Organizer

Data Source

[Presentation] Enterococcal linear plasmids adapt to Enterococcus faecium and spread within multidrug-resistant clades.2023

Author(s)

Organizer

Data Source

[Presentation] Analysis of a novel drug resistance determinant and epidemiology of pELF1-type linear plasmid associated with multidrug resistance in vancomycin-resistant enterococci detected isolated in a metropolitan aquatic environment in Vietnam2023

Author(s)

Organizer

Data Source

[Presentation] 腸球菌のpELF1型線状プラスミドと新規薬剤排出ポンプ遺伝子2023

Author(s)

Organizer

Data Source

[Presentation] 腸球菌のpELF1型高頻度接合伝達性プラスミドの研究2022

Author(s)

Organizer

Data Source

Hashimoto Yusuke 橋本佑輔

[Presentation] VanD型バンコマイシン耐性遺伝子群保有genomic islandの宿主多様性に関する分子疫学解析2021