Umehara Yoshie 梅原芳恵

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UMEHARA Yoshie 梅原芳恵

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Researcher Number	40707072
Other IDs	https://orcid.org/0000-0001-9039-0644
Affiliation (Current)	2025: 順天堂大学, 大学院医学研究科, 助教
Affiliation (based on the past Project Information) *help	2024: 順天堂大学, 大学院医学研究科, 助教 2015 – 2018: 順天堂大学, 医学(系)研究科(研究院), 博士研究員 2017: 順天堂大学, 医学研究科, 博士研究員 2016: 順天堂大学, 医学(系)研究科(研究院), 特任研究員 2015: 順天堂大学, 大学院医学研究科, 博士研究員 2014: 順天堂大学, 医学(系)研究科(研究院), 研究員
Review Section/Research Field	Principal Investigator Pain science / Basic Section 56070:Plastic and reconstructive surgery-related Except Principal Investigator Pain science / Dermatology
Keywords	Principal Investigator 抗菌ペプチド / 難治性かゆみ / 線維芽細胞 / 創傷治癒 / Sema3A / かゆみ / ドライスキン / アトピー性皮膚炎モデルNC/Ngaマウス / カテリシジン / アトピー性皮膚炎 … More / iPS細胞 / 末梢かゆみ神経 / ヒトiPS細胞 / 末梢神経 … More Except Principal Investigator かゆみ / アトピー性皮膚炎 / 難治性かゆみ / 後根神経節 / サテライトグリア細胞 / リポカリン２ / 感覚神経 / サテライトグリア / かゆみ過敏 / 抗菌ペプチド / 神経反発因子 Less

創傷治癒の線維芽細胞・表皮角化細胞間クロストークにおける抗菌ペプチドの役割解明Principal Investigator
- Principal Investigator
  
  梅原芳恵
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56070:Plastic and reconstructive surgery-related
- Research Institution
  Juntendo University
Effect of antimicrobial peptide cathelicidin on atopic dermatitisPrincipal Investigator
- Principal Investigator
  
  Umehara Yoshie
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pain science
- Research Institution
  Juntendo University
Elucidation of mechanisms of peripheral itch hypersensitivity focusing on dorsal root ganglia and development for its therapeutic application
- Principal Investigator
  
  TAKAMORI KENJI
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pain science
- Research Institution
  Juntendo University
A method to differentiate peripheral neurons mediating itch from human induced pluripotent stem cellsPrincipal Investigator
- Principal Investigator
  
  UMEHARA Yoshie
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pain science
- Research Institution
  Juntendo University
Cathelicidin LL-37 induces semaphorin 3A expression in human epidermal keratinocytes: implications for possible application to pruritus
- Principal Investigator
  
  Kamata Yayoi
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Dermatology
- Research Institution
  Juntendo University

All 2018 2017 2016 2015 2014 Other

All Journal Article Presentation Patent

[Journal Article] Bepotastine besilate downregulates the expression of nerve elongation factors in normal human epidermal keratinocytes2018
- Author(s)
  Kamata Yayoi、Sakaguchi Azumi、Umehara Yoshie、Suga Yasushi、Ogawa Hideoki、Tominaga Mitsutoshi、Takamori Kenji
- Journal Title
  
  Journal of Dermatological Science
  
  Volume: 91 Issue: 2 Pages: 219-222
- DOI
  10.1016/j.jdermsci.2018.04.012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08997, KAKENHI-PROJECT-18K07396
[Journal Article] Involvement of μ-opioid Receptors and κ-opioid Receptors in Itch-related Scratching Behaviour of Imiquimod-induced Psoriasis-like Dermatitis in Mice2017
- Author(s)
  Takahashi N, Tominaga M, Kosaka R, Kamata Y, Umehara Y, Matsuda H, Sakaguchi A, Ogawa H, Takamori K
- Journal Title
  
  Acta Dermato Venereologica
  
  Volume: 97 Issue: 8 Pages: 928-933
- DOI
  10.2340/00015555-2704
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K19217, KAKENHI-PROJECT-15K08680
[Journal Article] Oral administration of milk-derived phospholipids inhibits penetration of cutaneous nerve fibres into epidermis in a mouse model of acute dry skin2017
- Author(s)
  Sakaguchi A, Kamata Y, Takahashi N, Matsuda H, Kosaka R, Umehara Y, Ogawa H, Tominaga M, Takamori K
- Journal Title
  
  Clinical and Experimental Dermatology
  
  Volume: 42 Issue: 8 Pages: 890-894
- DOI
  10.1111/ced.13207
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K19217, KAKENHI-PROJECT-16K19739, KAKENHI-PROJECT-15K08680
[Journal Article] Antimicrobial peptides human LL-37 and β-defensin-3 modulate the expression of nerve elongation factors in human epidermal keratinocytes2017
- Author(s)
  Umehara Yoshie、Kamata Yayoi、Tominaga Mitsutoshi、Niyonsaba Fran?ois、Ogawa Hideoki、Takamori Kenji
- Journal Title
  
  Journal of Dermatological Science
  
  Volume: 88 Issue: 3 Pages: 365-367
- DOI
  10.1016/j.jdermsci.2017.07.010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10254, KAKENHI-PROJECT-16K19217, KAKENHI-PROJECT-16K19739
[Journal Article] Oral administration of milk-derived phospholipids inhibits a penetration of cutaneous nerve fibers into epidermis in an acute dry skin model mouse.2017
- Author(s)
  Sakaguchi A, Kamata Y, Takahashi N, Matsuda H, Kosaka R, Umehara Y, Ogawa H, Tominaga M, Takamori K.
- Journal Title
  
  Clin Exp Dermatol
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08997
[Journal Article] Differences in therapeutic effects of topically applied corticosteroid and tacrolimus on atopic dermatitis-like symptoms in NC/Nga mice.2016
- Author(s)
  Atsushi Noguchi, Mitsutoshi Tominaga, Nobuaki Takahashi, Hironori Matsuda, Yayoi Kamata, Yoshie Umehara, Ko Kyi Chan, Yasushi Suga, Hideoki Ogawa, Kenji Takamori
- Journal Title
  
  J Dermatol Sci
  
  Volume: 86 Issue: 1 Pages: 54-62
- DOI
  10.1016/j.jdermsci.2016.12.015
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K19217, KAKENHI-PROJECT-16K19739, KAKENHI-PROJECT-16K08997, KAKENHI-PROJECT-15K08680
[Journal Article] Possible anti-pruritic mechanisms of cyclosporine A in atopic dermatitis.2016
- Author(s)
  Ko KC, Tominaga M, Kamata Y, Umehara Y, Matsuda H, Takahashi N, Kina K, Ogawa M, Ogawa H, Takamori K.
- Journal Title
  
  Acta Derm Venereol
  
  Volume: 未定 Issue: 5 Pages: 624-629
- DOI
  10.2340/00015555-2318
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08680, KAKENHI-PROJECT-13J09449, KAKENHI-PROJECT-25460727, KAKENHI-PROJECT-26860386, KAKENHI-PROJECT-16K19217, KAKENHI-PROJECT-16K19739, KAKENHI-PROJECT-16K08997
[Journal Article] Neurotropin suppresses itch-related behavior in NC/Nga mice with atopic dermatitis-like symptoms.2016
- Author(s)
  Kamo A, Tominaga M, Matsuda H, Kina K, Kamata Y, Umehara Y, Ogawa H, Takamori K.
- Journal Title
  
  J Dermatol Sci
  
  Volume: 81 Issue: 3 Pages: 212-215
- DOI
  10.1016/j.jdermsci.2015.11.014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08680, KAKENHI-PROJECT-15K19193, KAKENHI-PROJECT-13J09449, KAKENHI-PROJECT-25460727, KAKENHI-PROJECT-26860386, KAKENHI-PROJECT-16K19217
[Journal Article] Relationships among plasma granzyme B level, pruritus and dermatitis in patients with atopic dermatitis.2016
- Author(s)
  Kamata Y, Kimura U, Matsuda H, Tengara S, Kamo A, Umehara Y, Iizumi K, Kawasaki H, Suga Y, Ogawa H, Tominaga M, Takamori K.
- Journal Title
  
  J Dermatol Sci
  
  Volume: 84 Issue: 3 Pages: 266-271
- DOI
  10.1016/j.jdermsci.2016.09.009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K19193, KAKENHI-PROJECT-16K19217, KAKENHI-PROJECT-16K19739, KAKENHI-PROJECT-15K08680, KAKENHI-PROJECT-16K08997
[Journal Article] Retinoid-related orphan receptor alpha is involved in induction of semaphorin 3A expression in normal human epidermal keratinocytes2015
- Author(s)
  Yayoi Kamata, Mitsutoshi Tominaga, Azumi Sakaguchi, Yoshie Umehara, Osamu Negi, Hideoki Ogawa, Kenji Takamori
- Journal Title
  
  J Dermatol Sci
  
  Volume: 印刷中 Issue: 1 Pages: 84-86
- DOI
  10.1016/j.jdermsci.2015.03.015
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-13J09449, KAKENHI-PROJECT-25460727, KAKENHI-PROJECT-25860428, KAKENHI-PROJECT-26860386, KAKENHI-PROJECT-26860387, KAKENHI-PROJECT-26860898, KAKENHI-PROJECT-15K08680
[Journal Article] Cathelicidin LL-37 induces semaphorin 3A production in human epidermal keratinocytes: implications for possible application to pruritus.2015
- Author(s)
  Umehara Y, Kamata Y, Tominaga M, Niyonsaba F, Ogawa H, Takamori K.
- Journal Title
  
  J Invest Dermatol
  
  Volume: 135 Issue: 11 Pages: 2887-2890
- DOI
  10.1038/jid.2015.243
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08680, KAKENHI-PROJECT-26461703, KAKENHI-PROJECT-13J09449, KAKENHI-PROJECT-25460727, KAKENHI-PROJECT-26860386, KAKENHI-PROJECT-26860898
[Journal Article] Atopic Dermatitis ―Mechanisms of Itch―2015
- Author(s)
  Tominaga M, Kamata Y, Umehara Y, Ko KC, Kamo A, Takamori K
- Journal Title
  
  J Environ Dermatol Cutan Allergol
  
  Volume: 9 Pages: 1-11
- NAID
  40020346148
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26860386
[Journal Article] アトピー性皮膚炎 ―かゆみのメカニズム―2015
- Author(s)
  冨永光俊，鎌田弥生, 梅原芳恵, Kyi Chan Ko, 加茂敦子, 高森建二
- Journal Title
  
  J Environ Dermatol Cutan Allergol
  
  Volume: 9 Pages: 1-11
- NAID
  40020346148
- Data Source
  KAKENHI-PROJECT-26860898
[Patent] 抗菌ペプチドによるセマフォリン3Aの発現調節法2015
- Inventor(s)
  梅原、鎌田、冨永、Niyonsaba、髙森
- Industrial Property Rights Holder
  東レ株式会社
- Industrial Property Rights Type
  特許
- Filing Date
  2015-09-02
- Overseas
- Data Source
  KAKENHI-PROJECT-26860386
[Patent] 抗菌ペプチドによるセマフォリン3Aの発現調節法2014
- Inventor(s)
  梅原、鎌田、冨永、Niyonsaba、髙森
- Industrial Property Rights Holder
  順天堂大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2014-177778
- Filing Date
  2014-09-02
- Data Source
  KAKENHI-PROJECT-26860386
[Patent] 掻痒性皮膚疾患の治療又は予防剤2014
- Inventor(s)
  梅原芳恵, 鎌田弥生, 髙森建二　他2名
- Industrial Property Rights Holder
  梅原芳恵, 鎌田弥生, 髙森建二　他2名
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2014-177778
- Filing Date
  2014-09-02
- Data Source
  KAKENHI-PROJECT-26860898
[Presentation] 正常ヒト表皮角化細胞におけるセマフォリン3Aの発現制御に関与するシグナル伝達系の解析2018
- Author(s)
  鎌田弥生、梅原芳恵、坂口安澄、冨永光俊、髙森建二
- Organizer
  第91回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-16K08997
[Presentation] 乳由来リン脂質の経口投与は急性ドライスキンモデルマウスにおける表皮内神経線維の増生を抑制する2017
- Author(s)
  坂口　安澄、鎌田　弥生、高橋　伸明、松田　浩則、幸坂　涼平、梅原　芳恵、須賀　康、冨永　光俊、髙森　建二
- Organizer
  第47回日本皮膚アレルギー・接触皮膚炎学会総会学術大会
- Data Source
  KAKENHI-PROJECT-16K19217
[Presentation] Sema3A expression is regulated by calcium/PKC/MAPK/AP-1 signaling axis in normal human epidermal keratinocytes2017
- Author(s)
  Yayoi Kamata, Yoshie Umehara, Azumi Sakaguchi, Yasushi Suga, Mitsutoshi Tominaga, Kenji Takamori
- Organizer
  9th World Congress of Itch
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19217
[Presentation] Calcium increases semaphorin 3A expression by activating PKC/MAPK/AP-1 signaling axis in normal human epidermal keratinocytes2017
- Author(s)
  Yayoi Kamata, Yoshie Umehara, Azumi Sakaguchi, Yasushi Suga, Hideoki Ogawa, Mitsutoshi Tominaga, Kenji Takamori
- Organizer
  日本研究皮膚科学会第42回年次学術大会・総会
- Data Source
  KAKENHI-PROJECT-16K19217
[Presentation] A method to differentiate peripheral neurons from human induced pluripotent stem cells to develop treatments for intractable itch2017
- Author(s)
  Yoshie Umehara, Mitsutoshi Tominaga, Hironori Matsuda, Nobuaki Takahashi, Yayoi Kamata, Hideoki Ogawa, Kenji Takamori
- Organizer
  日本研究皮膚科学会第42回年次学術大会・総会
- Data Source
  KAKENHI-PROJECT-16K19217
[Presentation] Efficacy of kappa-opioid receptor agonist and mu-opioid receptor antagonist to treat itch in imiquimod-induced psoriasis-like dermatitis model.2016
- Author(s)
  Takahashi, Tominaga M, Kamata Y, Umehara Y, Matsuda H, Ogawa H, Takamori K.
- Organizer
  46th Annual Meeting of the European Society for Dermatological Research (ESDR)
- Place of Presentation
  Technical University of Munich, Munich, Germany
- Year and Date
  2016-09-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08997
[Presentation] ドラッグリポジショニングに向けたセマフォリン3A発現調節剤のin vitroスクリーニング2016
- Author(s)
  鎌田弥生、冨永光俊、坂口安澄、梅原芳恵、髙森建二
- Organizer
  第89回日本生化学会大会
- Place of Presentation
  仙台
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-16K19217
[Presentation] Serum lipocalin-2 is a potential biomarker for pruritus in patients with psoriasis2016
- Author(s)
  Mitsutoshi Tominaga, Nobuaki Takahashi, Utako Kimura, Yayoi Kamata, Yoshie Umehara, Yasushi Suga, Hideoki Ogawa, Kenji Takamori
- Organizer
  日本研究皮膚科学会第 41 回年次学術大会・総会
- Place of Presentation
  仙台
- Year and Date
  2016-12-09
- Data Source
  KAKENHI-PROJECT-16K19217
[Presentation] Effects of antimicrobial peptide LL-37 on expression of natural moisturizing factor-generating proteases in epidermal keratinocytes2016
- Author(s)
  Yoshie Umehara, Yayoi Kamata, Mitsutoshi Tominaga, Francois Niyonsaba, Hideoki Ogawa, Kenji Takamori
- Organizer
  日本研究皮膚科学会第 41 回年次学術大会・総会
- Place of Presentation
  仙台
- Year and Date
  2016-12-09
- Data Source
  KAKENHI-PROJECT-16K19217
[Presentation] An analgesic agent suppresses itch-related behavior in NC/Nga mice with atopic dermatitis-like symptoms.2016
- Author(s)
  Kamo A, Tominaga M, Matsuda H, Kina K, Kamata Y, Umehara Y, Ogawa H, Takamori K.
- Organizer
  46th Annual Meeting of the European Society for Dermatological Research (ESDR)
- Place of Presentation
  Technical University of Munich, Munich, Germany
- Year and Date
  2016-09-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08997
[Presentation] Involvement of opioid systems in itch-related behavior of imiquimod-induced psoriasis-like dermatitis model2016
- Author(s)
  Nobuaki Takahashi, Mitsutoshi Tominaga, Yayoi Kamata, Yoshie Umehara, Hironori Matsuda, Yasushi Suga, Hideoki Ogawa, Kenji Takamori
- Organizer
  日本研究皮膚科学会第 41 回年次学術大会・総会
- Place of Presentation
  仙台
- Year and Date
  2016-12-09
- Data Source
  KAKENHI-PROJECT-16K19217
[Presentation] 抗菌ペプチドLL-37は培養正常ヒト表皮角化細胞における神経反発因子semaphorin 3Aの発現を促進する2015
- Author(s)
  梅原芳恵、鎌田弥生、冨永光俊、Francois Niyonsaba、小川秀興、髙森建二
- Organizer
  第45回日本皮膚アレルギー・接触皮膚炎学会総会学術大会
- Place of Presentation
  島根
- Year and Date
  2015-11-20
- Data Source
  KAKENHI-PROJECT-26860386
[Presentation] The effects of cathelicidin LL-37 on semaphorin 3A expression in normal human epidermal keratinocytes2015
- Author(s)
  Yoshie Umehara, Yayoi Kamata, Mitsutoshi Tominaga, Niyonsaba F, Hideoki Ogawa, Kenji Takamori
- Organizer
  8th World Congress on Itch
- Place of Presentation
  Nara Kasugano International Forum
- Year and Date
  2015-09-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860898
[Presentation] The antimicrobial peptide cathelicidin LL-37 induces semaphorin 3A production in normal human epidermal keratinocytes2015
- Author(s)
  Yoshie Umehara, Yayoi Kamata, Mitsutoshi Tominaga, Niyonsaba F, Hideoki Ogawa, Kenji Takamori
- Organizer
  Society for Investigative Dermatology 2015 Annual Meeting
- Place of Presentation
  Hilton Atlanta
- Year and Date
  2015-05-08
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860898
[Presentation] Establishment of differentiation method for peripheral neurons mediating itch from human induced pluripotent stem cells2015
- Author(s)
  Umehara Y, Tominaga M, Matsuda H, Kamata Y, Takamori K
- Organizer
  第38回日本分子生物学会年会、第88回日本生化学会大会合同大会（BMB2015）
- Place of Presentation
  神戸
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26860386
[Presentation] Effects of antimicrobial peptides on expression of axon guidance molecules in normal human epidermal keratinocytes2015
- Author(s)
  Umehara Y, Kamata Y, Tominaga M, Niyonsaba F, Ogawa H, Takamori K
- Organizer
  日本研究皮膚科学会第 40 回年次学術大会・総会
- Place of Presentation
  岡山
- Year and Date
  2015-12-11
- Data Source
  KAKENHI-PROJECT-26860386
[Presentation] Effects of antimicrobial peptides on expression of axon guidance molecules in normal human epidermal keratinocytes2015
- Author(s)
  Yoshie Umehara, Yayoi Kamata, Mitsutoshi Tominaga, Niyonsaba F, Hideoki Ogawa, Kenji Takamori
- Organizer
  The 40th Annual Meeting of the Japanese Society for Investigative Dermatology
- Place of Presentation
  岡山コンベンションセンター
- Year and Date
  2015-12-11
- Data Source
  KAKENHI-PROJECT-26860898
[Presentation] Pleiotropic action of cyclosporine on pruritus of atopic dermatitis2015
- Author(s)
  Tominaga M, Ko KC, Kamata Y, Umehara Y, Matsuda H, Takahashi N, Kina K, Ogawa M, Ogawa H, Takamori K
- Organizer
  8th World Congress on Itch (WCI)
- Place of Presentation
  奈良
- Year and Date
  2015-09-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860386
[Presentation] The effects of cathelicidin LL-37 on semaphorin 3A expression in normal human epidermal keratinocytes2015
- Author(s)
  Umehara Y, Kamata Y, Tominaga M, Niyonsaba F, Ogawa H, Takamori K
- Organizer
  8th World Congress on Itch (WCI)
- Place of Presentation
  奈良
- Year and Date
  2015-09-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860386
[Presentation] 抗菌ペプチドLL-37は培養正常ヒト表皮角化細胞における神経反発因子semaphorin 3Aの発現を促進する2015
- Author(s)
  梅原芳恵、鎌田弥生、冨永光俊、Niyonsaba F、小川秀興、髙森建二
- Organizer
  第45回日本皮膚アレルギー・接触皮膚炎学会総会学術大会
- Place of Presentation
  島根県民会館
- Year and Date
  2015-11-21
- Data Source
  KAKENHI-PROJECT-26860898
[Presentation] Inhibitory factors of semaphorin 3A expression in human epidermal keratinocytes2015
- Author(s)
  Kamata Y, Umehara Y, Tominaga M, Negi O, Ogawa H, Takamori K
- Organizer
  日本研究皮膚科学会第 40 回年次学術大会・総会
- Place of Presentation
  岡山
- Year and Date
  2015-12-11
- Data Source
  KAKENHI-PROJECT-26860386
[Presentation] Promoter analysis of semaphorin 3A gene in normal human epidermal keratinocytes2015
- Author(s)
  Kamata Y, Tominaga M, Umehara Y, Takamori K
- Organizer
  第38回日本分子生物学会年会、第88回日本生化学会大会合同大会（BMB2015）
- Place of Presentation
  神戸
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26860386
[Presentation] ヒスタミンH1受容体拮抗薬による表皮角化細胞における軸索ガイダンス分子の発現調節2015
- Author(s)
  鎌田弥生、坂口安澄、梅原芳恵、冨永光俊、根木治、小川秀興、高森建二
- Organizer
  第45回日本皮膚アレルギー・接触皮膚炎学会総会学術大会
- Place of Presentation
  島根
- Year and Date
  2015-11-20
- Data Source
  KAKENHI-PROJECT-26860386
[Presentation] Antimicrobial peptide LL-37 induces semaphorin 3A in normal human epidermal keratinocytes2014
- Author(s)
  Umehara Y, Kamata Y, Tominaga M, Niyonsaba F, Takamori K
- Organizer
  第24回国際痒みシンポジウム
- Place of Presentation
  東京
- Year and Date
  2014-10-18
- Data Source
  KAKENHI-PROJECT-26860386
[Presentation] 抗菌ペプチドLL-37は正常ヒト表皮角化細胞におけるsemaphorin 3Aの発現を誘導する2014
- Author(s)
  梅原芳恵、鎌田弥生、冨永光俊、François Niyonsaba、髙森建二
- Organizer
  第24回国際痒みシンポジウム
- Place of Presentation
  ベルサール神保町（東京都千代田区）
- Year and Date
  2014-10-18
- Data Source
  KAKENHI-PROJECT-26860898
[Presentation] Antipruritic mechanisms of cyclosporine A in an atopic dermatitis in mouse2014
- Author(s)
  Ko KC, Tominaga M, Kamata Y, Umehara Y, Takamori K
- Organizer
  第24回国際痒みシンポジウム
- Place of Presentation
  東京
- Year and Date
  2014-10-18
- Data Source
  KAKENHI-PROJECT-26860386
[Presentation] アトピー性皮膚炎モデルマウスにおけるシクロスポリンAの痒み抑制メカニズム2014
- Author(s)
  Kyi Chan Ko、冨永光俊、鎌田弥生、梅原芳恵、髙森建二
- Organizer
  第24回国際痒みシンポジウム
- Place of Presentation
  ベルサール神保町（東京都千代田区）
- Year and Date
  2014-10-18
- Data Source
  KAKENHI-PROJECT-26860898
[Presentation] Effects of antimicrobial peptides on semaphorin 3A expression in normal human epidermal keratinocytes．
- Author(s)
  Yoshie Umehara, Yayoi Kamata, Mitsutoshi Tominaga, François Niyonsaba, Kenji Takamori
- Organizer
  日本研究皮膚科学会　第39回年次学術大会・総会
- Place of Presentation
  ホテル阪急エキスポパーク（大阪府吹田市）
- Year and Date
  2014-12-12 – 2014-12-14
- Data Source
  KAKENHI-PROJECT-26860898
[Presentation] Effects of H1-antihistamines on expression of axon guidance molecules in normal human epidermal keratinocytes
- Author(s)
  Kamata Y, Sakaguchi A, Umehara Y, Tominaga M, Ogawa H, Takamori K
- Organizer
  Society for Investigative Dermatology Annual Meeting
- Place of Presentation
  Atlanta
- Year and Date
  2015-05-06 – 2015-05-09
- Data Source
  KAKENHI-PROJECT-26860386
[Presentation] Role of cyclosporine A in inhibitory mechanism of pruritus in atopic dermatitis.
- Author(s)
  Kyi Chan Ko, Mitsutoshi Tominaga, Yayoi Kamata, Yoshie Umehara, Kenji Takamori
- Organizer
  日本研究皮膚科学会　第39回年次学術大会・総会
- Place of Presentation
  ホテル阪急エキスポパーク（大阪府吹田市）
- Year and Date
  2014-12-12 – 2014-12-14
- Data Source
  KAKENHI-PROJECT-26860898
[Presentation] The retinoid-related orphan receptor ROR alpha promotes semaphorin 3A expression in human keratinocytes．
- Author(s)
  Yayoi Kamata, Mitsutoshi Tominaga, Yoshie Umehara, Kenji Takamori
- Organizer
  Society for Investigative Dermatology 2014 Annual Meeting
- Place of Presentation
  Albuquerque Convention Center (Albuquerque, USA)
- Year and Date
  2014-05-07 – 2014-05-10
- Data Source
  KAKENHI-PROJECT-26860898
[Presentation] Role of cyclosporine A in inhibitory mechanism of pruritus in atopic dermatitis
- Author(s)
  Ko KC, Tominaga M, Kamata Y, Umehara Y, Takamori K
- Organizer
  日本研究皮膚科学会第39回年次学術大会・総会
- Place of Presentation
  大阪
- Year and Date
  2014-12-12 – 2014-12-14
- Data Source
  KAKENHI-PROJECT-26860386
[Presentation] The retinoid-related orphan receptor RORα promotes semaphorin 3A expression in human keratinocytes
- Author(s)
  Kamata Y, Tominaga M, Umehara Y, Takamori K
- Organizer
  Society for Investigative Dermatology Annual Meeting
- Place of Presentation
  Albuquerque
- Year and Date
  2014-05-07 – 2014-05-10
- Data Source
  KAKENHI-PROJECT-26860386
[Presentation] Effect of antimicrobial peptides on semaphorin 3A expression in normal human epidermal keratinocytes
- Author(s)
  Umehara Y, Kamata Y, Tominaga M, Niyonsaba F, Takamori K
- Organizer
  日本研究皮膚科学会第39回年次学術大会・総会
- Place of Presentation
  大阪
- Year and Date
  2014-12-12 – 2014-12-14
- Data Source
  KAKENHI-PROJECT-26860386
[Presentation] The antimicrobial peptide cathelicidin LL-37 induces semaphorin 3A production in normal human epidermal keratinocytes
- Author(s)
  Umehara Y, Kamata Y, Tominaga M, Niyonsaba F, Ogawa H, Takamori K
- Organizer
  Society for Investigative Dermatology Annual Meeting
- Place of Presentation
  Atlanta
- Year and Date
  2015-05-06 – 2015-05-09
- Data Source
  KAKENHI-PROJECT-26860386

1. TOMINAGA Mitsutoshi (50468592)

# of Collaborated Projects: 3 results

# of Collaborated Products: 36 results
2. Kamata Yayoi (00410035)

# of Collaborated Projects: 3 results

# of Collaborated Products: 30 results
3. NIYONSABA Francois (60365640)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
4. MATSUDA Hironori

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
5. TAKAMORI KENJI (40053144)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
6. 加茂敦子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Umehara Yoshie 梅原 芳恵

UMEHARA Yoshie 梅原 芳恵

Research Projects

Research Products

Co-Researchers

創傷治癒の線維芽細胞・表皮角化細胞間クロストークにおける抗菌ペプチドの役割解明Principal Investigator

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Effect of antimicrobial peptide cathelicidin on atopic dermatitisPrincipal Investigator

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Elucidation of mechanisms of peripheral itch hypersensitivity focusing on dorsal root ganglia and development for its therapeutic application

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A method to differentiate peripheral neurons mediating itch from human induced pluripotent stem cellsPrincipal Investigator

Principal Investigator

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Cathelicidin LL-37 induces semaphorin 3A expression in human epidermal keratinocytes: implications for possible application to pruritus

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[Journal Article] Bepotastine besilate downregulates the expression of nerve elongation factors in normal human epidermal keratinocytes2018

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[Journal Article] Involvement of μ-opioid Receptors and κ-opioid Receptors in Itch-related Scratching Behaviour of Imiquimod-induced Psoriasis-like Dermatitis in Mice2017

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[Journal Article] Oral administration of milk-derived phospholipids inhibits penetration of cutaneous nerve fibres into epidermis in a mouse model of acute dry skin2017

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[Journal Article] Antimicrobial peptides human LL-37 and β-defensin-3 modulate the expression of nerve elongation factors in human epidermal keratinocytes2017

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[Journal Article] Oral administration of milk-derived phospholipids inhibits a penetration of cutaneous nerve fibers into epidermis in an acute dry skin model mouse.2017

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[Journal Article] Differences in therapeutic effects of topically applied corticosteroid and tacrolimus on atopic dermatitis-like symptoms in NC/Nga mice.2016

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[Journal Article] Possible anti-pruritic mechanisms of cyclosporine A in atopic dermatitis.2016

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[Journal Article] Neurotropin suppresses itch-related behavior in NC/Nga mice with atopic dermatitis-like symptoms.2016

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[Journal Article] Relationships among plasma granzyme B level, pruritus and dermatitis in patients with atopic dermatitis.2016

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[Journal Article] Retinoid-related orphan receptor alpha is involved in induction of semaphorin 3A expression in normal human epidermal keratinocytes2015

Umehara Yoshie 梅原芳恵

UMEHARA Yoshie 梅原芳恵