Okamoto Kazuko 岡本和子

Researcher Number	40710265
Other IDs	https://orcid.org/0000-0001-9874-5710
Affiliation (Current)	2026: 広島大学, 両生類研究センター, 助教
Affiliation (based on the past Project Information) *help	2022 – 2025: 広島大学, 両生類研究センター, 助教 2020 – 2022: 金沢大学, ナノ生命科学研究所, 特任助教 2019: 国立研究開発法人理化学研究所, 生命機能科学研究センター, 研究員 2015 – 2016: 国立研究開発法人理化学研究所, 生命システム研究センター, 特別研究員
Review Section/Research Field	Principal Investigator Basic Section 44010:Cell biology-related / Basic Section 44020:Developmental biology-related / Biophysics Except Principal Investigator Basic Section 48010:Anatomy-related / Basic Section 18010:Mechanics of materials and materials-related
Keywords	Principal Investigator 転写因子 / 1分子計測 / 単一粒子追跡 / 相分離 / クロマチン / 脱分化 / 粘弾性 / 両生類 / 核内動態 / １分子計測 … More / 核 / ES細胞 / Nanog / リプログラミング / 未分化 / FRET / PALM / 細胞分化 / ヒストン修飾 … More Except Principal Investigator p53 / 細胞周期 / イベリアトゲイモリ / メカノバイオロジー / 多細胞力学 / 材料力学試験 / 生体力学 Less

がん抑制におけるp53の機能をTY型変異イモリの皮膚腫瘍の発生機序から解明する
- Principal Investigator
  
  林利憲
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 48010:Anatomy-related
- Research Institution
  Hiroshima University
Active mechanical properties of three-dimensional multicellular tissues and their adaptive regulatory mechanisms
- Principal Investigator
  
  Okuda Satoru
- Project Period (FY)
  2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 18010:Mechanics of materials and materials-related
- Research Institution
  Kanazawa University
Viscoelastic properties in the nucleus control spatial fluctuations in transcriptional regulatory regions of NanogPrincipal Investigator
- Principal Investigator
  
  Okamoto Kazuko
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 44010:Cell biology-related
- Research Institution
  Hiroshima University
Molecular dynamics of Nanog on its binding loci facilitates to induce ground state pluripotencyPrincipal Investigator
- Principal Investigator
  
  Okamoto Kazuko
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 44020:Developmental biology-related
- Research Institution
  Kanazawa University
  Institute of Physical and Chemical Research
Development of super-resolution microscopic live imaging method of histone modifications for understanding cell differentiation and reprogrammingPrincipal Investigator
- Principal Investigator
  
  Okamoto Kazuko
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biophysics
- Research Institution
  Institute of Physical and Chemical Research

All 2024 2023 2022 2020 2019 2016 2015

All Journal Article Presentation

[Journal Article] Single‐molecule tracking of Nanog and Oct4 in living mouse embryonic stem cells uncovers a feedback mechanism of pluripotency maintenance2023
- Author(s)
  Okamoto Kazuko、Fujita Hideaki、Okada Yasushi、Shinkai Soya、Onami Shuichi、Abe Kuniya、Fujimoto Kenta、Sasaki Kensuke、Shioi Go、Watanabe Tomonobu M
- Journal Title
  
  The EMBO Journal
  
  Volume: 42 Issue: 18
- DOI
  10.15252/embj.2022112305
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06201, KAKENHI-PUBLICLY-23H04297, KAKENHI-PROJECT-22H04926, KAKENHI-PROJECT-21H03599, KAKENHI-ORGANIZER-19H05794, KAKENHI-PLANNED-19H05795
[Journal Article] Single-molecule tracking of Nanog and Oct4 in mouse embryonic stem cells2022
- Author(s)
  Okamoto Kazuko、Fujita Hideaki、Okada Yasushi、Shinkai Soya、Onami Shuichi、Abe Kuniya、Fujimoto Kenta、Watanabe Tomonobu M
- Journal Title
  
  bioRxiv
  
  Volume: －
- DOI
  10.1101/2022.08.08.503148
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K06201, KAKENHI-PLANNED-18H05412
[Journal Article] From a young BSJ member: advanced technologies encouraged me to dive into biophysics field2020
- Author(s)
  Kazuko Okamoto
- Journal Title
  
  Biophysical Reviews
  
  Volume: - Issue: 2 Pages: 205-206
- DOI
  10.1007/s12551-020-00648-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K16158
[Presentation] イベリアトゲイモリ線維芽細胞が呈示する高温下での熱ストレス抵抗性2024
- Author(s)
  賀然、山根大和、竹原舞、*林利憲、*岡本和子
- Organizer
  第47回日本分子生物学会年会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06201
[Presentation] Attempts at cell culture methods in Iberian ribbed newts2024
- Author(s)
  Kazuko Okamoto
- Organizer
  International Salamander Meeting 2024
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06201
[Presentation] Spatiotemporal Dynamics of Lumen Formation in Single ESC-derived Neural Tube-like Spheroid2023
- Author(s)
  Kazuko Okamoto
- Organizer
  the 56th annual meeting of the Japanese Society of Developmental Biologists
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06201
[Presentation] Spatiotemporal analysis of lumen formation using single cell-derived neural tube-forming mimetic spheroids2023
- Author(s)
  Kazuko Okamoto
- Organizer
  The 47th Annual Meeting of the Molecular Biology Society of Japan
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06201
[Presentation] 転写因子の振る舞いとクロマチンのゆらぎの関係性を1分子計測によって解析する2020
- Author(s)
  岡本和子, 岡田康志, 阿倍訓也, 渡邉朋信
- Organizer
  第72回日本細胞生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-19K16158
[Presentation] 転写因子の振る舞いとクロマチンのゆらぎの関係性を1分子計測によって解析する2019
- Author(s)
  岡本和子, 岡田康志, 阿倍訓也, 渡邉朋信
- Organizer
  第57回生物物理学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-19K16158
[Presentation] クロマチンのゆらぎと転写調節機構の関係性を転写因子1分子計測によって解析する2019
- Author(s)
  岡本和子, 岡田康志, 渡邉朋信
- Organizer
  第19回日本蛋白質科学年会・第71回日本細胞生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-19K16158
[Presentation] ES細胞のコロニーが、集団として不均一性を保つ仕組み2016
- Author(s)
  岡本和子, 垣塚太志, 藤田英明, 渡邉朋信
- Organizer
  第68回日本細胞生物学会大会年会
- Place of Presentation
  京都テルサ (京都府・京都市）
- Year and Date
  2016-06-15
- Data Source
  KAKENHI-PROJECT-15K21629
[Presentation] The mechanism by which cellular heterogeneity propagates heterogeneity in colonies2016
- Author(s)
  Kazuko Okamoto, Hideaki Fujita, Chikara Furusawa, Tomonobu Watanabe
- Organizer
  17th International Conference on Systems Biology
- Place of Presentation
  the Palau de Congressos at Fira BCN (スペイン・バルセロナ)
- Year and Date
  2016-09-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K21629
[Presentation] ES細胞初期分化にみる細胞個体と細胞集団との関係性を定量する2015
- Author(s)
  岡本和子, 垣塚太志, 藤田英明, 渡邉朋信
- Organizer
  第67回日本細胞生物学会大会年会
- Place of Presentation
  タワーホール船堀（東京都・江戸川区）
- Year and Date
  2015-06-30
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K21629
[Presentation] Quantitative analysis of transition in the heterogeneity of embryonic stem cells during early differentiation2015
- Author(s)
  Kazuko Okamoto, Taishi kakizuka, Hideaki Fujita, Tomonobu Watanabe
- Organizer
  第48回日本発生生物学会年会
- Place of Presentation
  つくば国際会議場（茨城県・つくば市）
- Year and Date
  2015-06-02
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K21629
[Presentation] Quantitative multi-layered observation of the correlations between a cell and a colony during early ESC differentiation2015
- Author(s)
  Kazuko Okamoto, Taishi kakizuka, Hideaki Fujita, Tomonobu Watanabe
- Organizer
  第38回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド（兵庫県・神戸市）
- Year and Date
  2015-12-01
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K21629

1. Okuda Satoru (80707836)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. 林利憲 (60580925)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 鎌形清人 (90432492)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Okamoto Kazuko 岡本 和子

Research Projects

Research Products

Co-Researchers

がん抑制におけるp53の機能をTY型変異イモリの皮膚腫瘍の発生機序から解明する

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Active mechanical properties of three-dimensional multicellular tissues and their adaptive regulatory mechanisms

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Viscoelastic properties in the nucleus control spatial fluctuations in transcriptional regulatory regions of NanogPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Molecular dynamics of Nanog on its binding loci facilitates to induce ground state pluripotencyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of super-resolution microscopic live imaging method of histone modifications for understanding cell differentiation and reprogrammingPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Single‐molecule tracking of Nanog and Oct4 in living mouse embryonic stem cells uncovers a feedback mechanism of pluripotency maintenance2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Single-molecule tracking of Nanog and Oct4 in mouse embryonic stem cells2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] From a young BSJ member: advanced technologies encouraged me to dive into biophysics field2020

Author(s)

Journal Title

DOI

Data Source

[Presentation] イベリアトゲイモリ線維芽細胞が呈示する高温下での熱ストレス抵抗性2024

Author(s)

Organizer

Data Source

[Presentation] Attempts at cell culture methods in Iberian ribbed newts2024

Author(s)

Organizer

Data Source

[Presentation] Spatiotemporal Dynamics of Lumen Formation in Single ESC-derived Neural Tube-like Spheroid2023

Author(s)

Organizer

Data Source

[Presentation] Spatiotemporal analysis of lumen formation using single cell-derived neural tube-forming mimetic spheroids2023

Author(s)

Organizer

Data Source

[Presentation] 転写因子の振る舞いとクロマチンのゆらぎの関係性を1分子計測によって解析する2020

Author(s)

Organizer

Data Source

[Presentation] 転写因子の振る舞いとクロマチンのゆらぎの関係性を1分子計測によって解析する2019

Author(s)

Organizer

Data Source

[Presentation] クロマチンのゆらぎと転写調節機構の関係性を転写因子1分子計測によって解析する2019

Author(s)

Organizer

Data Source

[Presentation] ES細胞のコロニーが、集団として不均一性を保つ仕組み2016

Author(s)

Organizer

Okamoto Kazuko 岡本和子