Tomohara Keisuke 友原啓介

… Alternative Names

TOMOHARA KEISUKE 友原啓介

Less

Researcher Number	40711677
Other IDs
Affiliation (Current)	2025: 京都薬科大学, 薬学部, 講師
Affiliation (based on the past Project Information) *help	2023 – 2025: 京都薬科大学, 薬学部, 講師 2017 – 2022: 九州大学, 基幹教育院, 助教 2016: 富山大学, 附属病院, 助教 2014 – 2015: 富山大学, 大学病院, 助教
Review Section/Research Field	Principal Investigator Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related / Basic Section 37020:Chemistry and chemical methodology of biomolecules-related / Chemical pharmacy / Natural medicines Except Principal Investigator Basic Section 64030:Environmental materials and recycle technology-related / Medium-sized Section 64:Environmental conservation measure and related fields / Basic Section 64020:Environmental load reduction and remediation-related
Keywords	Principal Investigator アンモニア-Ugi反応 / 非天然型アミノ酸 / 多成分系の分子変換 / ジメチルスルホキシド / ペプチド / ケミカルスペース / 一斉合成 / 植物分子 / 天然物抽出物 / 天然物コネクテッド型分子 … More / ペプチド合成 / 非天然型α,α-2置換アミノ酸 / 天然物コネクティッド型分子 / 非天然型ペプチド / Ugi反応 / 天然物様分子 / 天然物誘導体 / 分子間相互作用解析 / 学際的創薬化学 / DMSO摂動効果 / 非特異的酵素阻害剤 / 多成分系 / 非特異的結合 / 摂動 / DMSO / 酵素阻害剤 / 非特異的阻害 / 摂動効果 / 天然物様化合物 / 化学的一挙誘導化 / 生薬成分抽出 / 複雑系 / 非特異的阻害剤 / 化学的直接誘導化 / ヒアルロン酸分解酵素 / 非特異的分子間相互作用 / 化学的摂動効果 / ヒアルロニダーゼ / ヒダントイン / アミノ酸誘導体 / 多成分の分子変換 / 生薬 … More Except Principal Investigator ペプチド / エラスチンペプチド / ペプチド素材 / 有害化学物質除去 / 環境調和型 / 天然由来タンパク質 / 人工網モデル / エラスチン様ペプチド / 温度応答性 / 有害物吸着 / 疎水性芳香族化合物 / マイクロプラスチック / タンパク質資源 / 未利用資源活用 / 環境調和型素材 / 循環型社会 / 天然タンパク質 / 自己凝集 / 化学物質吸着 / 環境化学物質 / 吸着 / コアセルベーション Less

Development of catalytic ammonia-Ugi reaction and synthesis of unnatural peptidesPrincipal Investigator
- Principal Investigator
  
  友原啓介
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related
- Research Institution
  Kyoto Pharmaceutical University
環境水中の有害化学物質除去に資する環境調和型温度応答性ペプチド素材の設計と応用
- Principal Investigator
  
  野瀬健
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 64030:Environmental materials and recycle technology-related
- Research Institution
  Kyushu University
Simultaneous synthesis of natural product hybrids and discovery of unexplored natural productsPrincipal Investigator
- Principal Investigator
  
  TOMOHARA Keisuke
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 37020:Chemistry and chemical methodology of biomolecules-related
- Research Institution
  Kyoto Pharmaceutical University
  Kyushu University
Development of functional micro-particle capturing materials aimed at effectively utilizing natural protein resources
- Principal Investigator
  
  Nose Takeru
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Pioneering)
- Review Section
  
  Medium-sized Section 64:Environmental conservation measure and related fields
- Research Institution
  Kyushu University
Development of Adsorption System for Environmental Contaminants using temperature-responsive self-assembling peptides
- Principal Investigator
  
  Nose Takeru
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 64020:Environmental load reduction and remediation-related
- Research Institution
  Kyushu University
Interdisciplinary medicinal chemistry: Synthesis and biological evaluationPrincipal Investigator
- Principal Investigator
  
  Tomohara Keisuke
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Kyushu University
Development of extraction techniques for natural products and discovery of hyaluronan-degrading enzyme inhibitors from natural productsPrincipal Investigator
- Principal Investigator
  
  TOMOHARA KEISUKE
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Natural medicines
- Research Institution
  University of Toyama

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014

All Journal Article Presentation Book

[Book] ちびまる子ちゃんの社会学2021
- Author(s)
  三成清香, 遠藤英樹, 有賀敏典, 髙橋詩織, 井上登美子, 橋本愛, Jarunee Suwanrassamee, 日向伸介, 友原嘉彦, 高田晴美, 友原啓介
- Total Pages
  222
- Publisher
  古今書院
- ISBN
  9784772253406
- Data Source
  KAKENHI-PROJECT-21K05290
[Journal Article] Ugi Adducts as Novel Anti-austerity Agents against PANC-1 Human Pancreatic Cancer Cell Line: A Rapid Synthetic Approach2023
- Author(s)
  Keisuke Tomohara*, Juthamart Maneene, Nao Ohashi, Takeru Nose, Rintaro Fujii, Min Jo Kim, Sijia Sun, Suresh Awale*
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 46 Issue: 10 Pages: 1412-1420
- DOI
  10.1248/bpb.b23-00224
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2023-10-01
- Language
  English
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K05290, KAKENHI-PROJECT-23K26797
[Journal Article] Determining the Sequence Dependency of Self-Assembly of Elastin-Like Peptides Using Short Peptide Analogues with Shuffled Repetitive Sequences2023
- Author(s)
  Tatsubo Daiki、Suyama Keitaro、Sakamoto Naoki、Tomohara Keisuke、Taniguchi Suguru、Maeda Iori、Nose Takeru
- Journal Title
  
  Biochemistry
  
  Volume: 62 Issue: 17 Pages: 2559-2570
- DOI
  10.1021/acs.biochem.3c00146
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K12819, KAKENHI-PROJECT-21K05290, KAKENHI-PROJECT-20K20638, KAKENHI-PROJECT-22K20515
[Journal Article] Development of Temperature-responsive Peptides by EDTA-mediated Multimerization of Short (FPGVG)n Chains2022
- Author(s)
  Naoki Tanaka, Keitaro Suyama, Keisuke Tomohara, Iori Maeda, Takeru Nose
- Journal Title
  
  Peptide Science 2021
  
  Volume: 2022 Pages: 83-84
- Data Source
  KAKENHI-PROJECT-19H04303
[Journal Article] Metal ion scavenging activity of elastin-like peptide analogues containing a cadmium ion binding sequence2022
- Author(s)
  Sumiyoshi Shogo、Suyama Keitaro、Tatsubo Daiki、Tanaka Naoki、Tomohara Keisuke、Taniguchi Suguru、Maeda Iori、Nose Takeru
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1 Pages: 1861-1861
- DOI
  10.1038/s41598-022-05695-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K20202, KAKENHI-PROJECT-19H04303, KAKENHI-PROJECT-21K05290, KAKENHI-PROJECT-20K20638, KAKENHI-PROJECT-22K12819
[Journal Article] 夾雑系生薬抽出物を基質とした天然物コネクティッド型分子群の一斉化学合成2022
- Author(s)
  友原啓介
- Journal Title
  
  Farumashia
  
  Volume: 58 Issue: 12 Pages: 1120-1124
- DOI
  10.14894/faruawpsj.58.12_1120
- ISSN
  0014-8601, 2189-7026
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K05290
[Journal Article] Branched short elastin‐like peptides with temperature responsiveness obtained by EDTA‐mediated multimerization2022
- Author(s)
  Tanaka Naoki、Suyama Keitaro、Tomohara Keisuke、Maeda Iori、Nose Takeru
- Journal Title
  
  Journal of Peptide Science
  
  Volume: 29 Issue: 2
- DOI
  10.1002/psc.3449
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K12819, KAKENHI-PROJECT-20K20638
[Journal Article] Development of Temperature-responsive Peptides by EDTA-mediated Multimerization of Short (FPGVG)n Chains2022
- Author(s)
  Naoki Tanaka, Keitaro Suyama, Keisuke Tomohara, Iori Maeda, Takeru Nose
- Journal Title
  
  Peptide Science 2021
  
  Volume: 2022 Pages: 83-84
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K20638
[Journal Article] Development of temperature-responsive short-chain peptide analogues based on elastin-like peptide FPGVG2022
- Author(s)
  Keitaro Suyama, Shogo Sumiyoshi, Naoki Tanaka, Takumi Ando, Akihiko Nagata, Keisuke Tomohara, Suguru Taniguchi, Iori Maeda, Takeru Nose
- Journal Title
  
  Peptide Science 2021
  
  Volume: 2022 Pages: 141-142
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H04303
[Journal Article] Synthesis of natural product hybrids by the Ugi reaction in complex media containing plant extracts2022
- Author(s)
  Keisuke Tomohara*, Nao Ohashi, Tatsuya Uchida, Takeru Nose.
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1 Pages: 15568-15568
- DOI
  10.1038/s41598-022-19579-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K05290
[Journal Article] Development of truncated elastin-like peptide analogues with improved temperature-response and self-assembling properties2022
- Author(s)
  Sumiyoshi Shogo、Suyama Keitaro、Tanaka Naoki、Andoh Takumi、Nagata Akihiko、Tomohara Keisuke、Taniguchi Suguru、Maeda Iori、Nose Takeru
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1 Pages: 19414-19414
- DOI
  10.1038/s41598-022-23940-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K12819, KAKENHI-PROJECT-20K20638
[Journal Article] Development of Liposome Like Nanostructures Composed of Short Amphiphilic Elastin-Like Peptides2020
- Author(s)
  Naoki Sakamoto, Daiki Tatsubo, Keiji Sato, Keisuke Tomohara, Keitaro Suyama, Iori Maeda, Takeru Nose
- Journal Title
  
  Peptide Science 2019
  
  Volume: 2019 Pages: 113-114
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H04303
[Journal Article] Early identification of promiscuous attributes of aldose reductase inhibitors using a DMSO-perturbation assay2020
- Author(s)
  Keisuke Tomohara, Naoto Hasegawa, Isao Adachi, Yoshikazu Horino, Takeru Nose.
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: 30 Issue: 2 Pages: 126815-126815
- DOI
  10.1016/j.bmcl.2019.126815
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K17750
[Journal Article] DMSO-perturbing assay for identifying promiscuous enzyme inhibitors2019
- Author(s)
  Keisuke Tomohara, Isao Adachi, Yoshikazu Horino, Hitoshi Kesamaru, Hitoshi Abe, Keitaro Suyama, Takeru Nose.
- Journal Title
  
  ACS Medicinal Chemistry Letters
  
  Volume: 10 Issue: 6 Pages: 923-928
- DOI
  10.1021/acsmedchemlett.9b00093
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K17750
[Journal Article] Controllable Stereoselective Synthesis of (Z)- and (E)-Homoallylic Alcohols Using a Palladium-Catalyzed Three-Component Reaction2017
- Author(s)
  Horino Yoshikazu、Sugata Miki、Mutsuura Itaru、Tomohara Keisuke、Abe Hitoshi
- Journal Title
  
  Organic Letters
  
  Volume: 19 Issue: 21 Pages: 5968-5971
- DOI
  10.1021/acs.orglett.7b02979
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K17750, KAKENHI-PROJECT-15K05496
[Journal Article] Discovery of hyaluronidase inhibitors from natural products and their mechanistic characterization under DMSO-perturbed assay conditions2017
- Author(s)
  Keisuke Tomohara, Tomohiro Ito, Saika Onikata, Atsushi Kato, Isao Adachi
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: 27 Issue: 7 Pages: 1620-1623
- DOI
  10.1016/j.bmcl.2017.01.083
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26870217
[Journal Article] Multiple production of α,α-disubstituted amino acid derivatives through direct chemical derivatization of natural plant extracts: An apparently difficult but successful route2017
- Author(s)
  Tomohara Keisuke、Ito Tomohiro、Furusawa Kota、Hasegawa Naoto、Tsuge Kiyoshi、Kato Atsushi、Adachi Isao
- Journal Title
  
  Tetrahedron Letters
  
  Volume: 58 Issue: 32 Pages: 3143-3147
- DOI
  10.1016/j.tetlet.2017.06.087
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K17750
[Journal Article] Interpreting the behavior of concentration-response curves of hyaluronidase inhibitors under DMSO-perturbed assay conditions2016
- Author(s)
  Keisuke Tomohara, Tomohiro Ito, Saika Onikata, Kota Furusawa, Atsushi Kato, Isao Adachi
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: 26 Issue: 13 Pages: 3153-3157
- DOI
  10.1016/j.bmcl.2016.04.082
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26870217
[Journal Article] Direct chemical derivatization of natural plant extract: straightforward synthesis of natural plant-like hydantoin2016
- Author(s)
  Keisuke Tomohara, Tomohiro Ito, Naoto Hasegawa, Atsushi Kato, Isao Adachi
- Journal Title
  
  Tetrahedron Letters
  
  Volume: 57 Issue: 8 Pages: 924-927
- DOI
  10.1016/j.tetlet.2016.01.054
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26870217
[Journal Article] Another aspect in use of DMSO in medicinal chemistry2016
- Author(s)
  Keisuke Tomohara
- Journal Title
  
  Atlas of Science
  
  Volume: -
- Data Source
  KAKENHI-PROJECT-26870217
[Presentation] 天然物様分子の合成と生物活性評価2024
- Author(s)
  友原啓介
- Organizer
  京都薬科大学創薬科学フロンティア研究センター講演会
- Invited
- Data Source
  KAKENHI-PROJECT-21K05290
[Presentation] アンモニア-Ugi反応を用いたエラスチン様ペプチドアナログの合成2024
- Author(s)
  友原啓介, 草場智, 田中尚輝, 野瀬健
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-21K05290
[Presentation] 非天然型アミノ酸含有ペプチドの迅速合成と機能評価2023
- Author(s)
  友原啓介
- Organizer
  九州大学理学部化学教室公開講演会最新化学談話シリーズ令和５年度前期特別談話会
- Data Source
  KAKENHI-PROJECT-21K05290
[Presentation] Temperature-responsive behavior of branched molecules bearing pentapeptide units of elastin-like peptide (FPGVG)n2023
- Author(s)
  Naoki, Tanaka, Keitaro Suyama, Keisuke Tomohara, Takeru Nose
- Organizer
  第60回ペプチド討論会
- Data Source
  KAKENHI-PROJECT-20K20638
[Presentation] アンモニア-Ugi反応を用いた非天然型α,α-2置換アミノ酸含有ペプチドの実践的合成法の開発2023
- Author(s)
  草場智, 友原啓介, 野瀬健
- Organizer
  第21回次世代を担う有機化学シンポジウム
- Data Source
  KAKENHI-PROJECT-21K05290
[Presentation] アンモニア-Ugi反応の開発および非天然型α,α-２置換アミノ酸含有ペプチドのde novo合成への応用2023
- Author(s)
  草場智, 友原啓介, 野瀬健
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-21K05290
[Presentation] Synthesis of thermoresponsive elastin-like peptide analogs by peptide fragment condensation reaction using papain2023
- Author(s)
  Akihiko Nagata, Keisuke Tomohara, Keitaro Suyama, Takeru Nose
- Organizer
  第60回ペプチド討論会
- Data Source
  KAKENHI-PROJECT-20K20638
[Presentation] Regulation of reversible self-assembly ability by substitution and deletion of amino acid residues of elastin peptide (FPGVG)n analogs2023
- Author(s)
  Keitaro Suyama, Shogo Sumiyoshi, Marin Shimizu, Naoki Tanaka, Keisuke Tomohara, Suguru Taniguchi, Iori Maeda, Takeru Nose.
- Organizer
  日本化学会第103回春季年会
- Data Source
  KAKENHI-PROJECT-20K20638
[Presentation] 配座固定型α-キモトリプシン阻害剤の設計・合成・阻害活性評価2023
- Author(s)
  草場智, 友原啓介, 野瀬健
- Organizer
  第60回化学関連支部合同九州大会
- Data Source
  KAKENHI-PROJECT-21K05290
[Presentation] 温度応答性ペプチド・(FPGVG)5の配列短縮による自己集合能の増強2022
- Author(s)
  巣山慶太郎、住吉勝伍、田中尚輝、安藤拓海、長田晃彦、友原啓介、谷口卓、前田衣織、野瀬　健
- Organizer
  令和4年度日本生化学会九州支部例会
- Data Source
  KAKENHI-PROJECT-20K20638
[Presentation] 金属結合性配列を導入した短鎖エラスチン様ペプチドアナログの金属結合性2021
- Author(s)
  田中尚輝、住吉勝伍、巣山慶太郎、友原啓介、前田衣織、野瀬健
- Organizer
  令和 3 年度日本生化学会九州支部例会
- Data Source
  KAKENHI-PROJECT-19H04303
[Presentation] Development of Temperature-responsive Peptides by EDTA-mediated Multimerization of Short (FPGVG)n Chains2021
- Author(s)
  Naoki Tanaka, Keitaro Suyama, Keisuke Tomohara, Iori Maeda, Takeru Nose
- Organizer
  第58回ペプチド討論会
- Data Source
  KAKENHI-PROJECT-19H04303
[Presentation] Development of Temperature-responsive Short-chain Peptide Analogues Based on Elastin-like Peptide FPGVG2021
- Author(s)
  Keitaro Suyama, Shogo Sumiyoshi, Naoki Tanaka, Takumi Ando, Akihiko Nagata, Keisuke Tomohara, Suguru Taniguchi, Iori Maeda, Takeru Nose
- Organizer
  第58回ペプチド討論会
- Data Source
  KAKENHI-PROJECT-19H04303
[Presentation] Development of Temperature-responsive Peptides by EDTA-mediated Multimerization of Short (FPGVG)n Chains2021
- Author(s)
  Naoki Tanaka, Keitaro Suyama, Keisuke Tomohara, Iori Maeda, Takeru Nose
- Organizer
  第58回ペプチド討論会
- Data Source
  KAKENHI-PROJECT-20K20638
[Presentation] ハイブリッド型天然物様 Ugi 付加体の一斉化学合成2021
- Author(s)
  友原啓介、大橋奈央、野瀬健
- Organizer
  第23回天然薬物の開発と応用シンポジウム
- Data Source
  KAKENHI-PROJECT-21K05290
[Presentation] 溶媒摂動効果を利用した酵素阻害剤の特異性評価2019
- Author(s)
  大橋奈央、友原啓介、野瀬健
- Organizer
  第36回日本薬学会九州支部大会
- Data Source
  KAKENHI-PROJECT-17K17750
[Presentation] Development of liposome-like nanostructures composed of short amphiphilic elastin-like peptides2019
- Author(s)
  Naoki Sakamoto, Daiki Tatsubo, Keiji Sato, Keisuke Tomohara, Keitaro Suyama, Iori Maeda, Takeru Nose.
- Organizer
  第56回ペプチド討論会
- Data Source
  KAKENHI-PROJECT-17K17750
[Presentation] Development of liposome-like nanostructures composed of short amphiphilic elastin-like peptides2019
- Author(s)
  Naoki Sakamoto, Daiki Tatsubo, Keiji Sato, Keisuke Tomohara, Keitaro Suyama, Iori Maeda, Takeru Nose
- Organizer
  The 56th Japanese Peptide Symposium
- Data Source
  KAKENHI-PROJECT-19H04303
[Presentation] DMSO摂動法を用いたアルドースレダクターゼ阻害剤の活性部位特異性評価2019
- Author(s)
  友原啓介、長谷川直人、足立伊佐雄、野瀬健
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-17K17750
[Presentation] 溶媒摂動効果を利用した初期スクリーニングヒットのバリデーション2019
- Author(s)
  友原啓介、大橋奈央、栗木暖佳、巣山慶太郎、野瀬健
- Organizer
  第37回メディシナルケミストリーシンポジウム
- Data Source
  KAKENHI-PROJECT-17K17750
[Presentation] DMSO摂動効果を利用した酵素阻害剤の活性部位特異性評価2018
- Author(s)
  友原啓介，袈裟丸仁志，足立伊佐雄，巣山慶太郎，野瀬健
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-17K17750
[Presentation] Mechanistic Characterization of alpha-Chymotrypsin Inhibitors by DMSO-Perturbing Assay2018
- Author(s)
  Keisuke Tomohara, Isao Adachi, Hitoshi Kesamaru, Takeru Nose
- Organizer
  10th International Peptide Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K17750
[Presentation] DMSO-perturbing assay for identifying promiscuous enzyme inhibitors.2018
- Author(s)
  Keisuke Tomohara
- Organizer
  The Third International Symposium on Toyama-Asia-Africa Pharmaceutical Network
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K17750
[Presentation] DMSO添加条件下における酵素阻害剤の活性部位特異性評価2018
- Author(s)
  友原啓介、足立伊佐雄、袈裟丸仁志、野瀬健
- Organizer
  平成30年度日本生化学会九州支部例会
- Data Source
  KAKENHI-PROJECT-17K17750
[Presentation] 極性変換を鍵とする多成分系の分子変換2017
- Author(s)
  古沢晃太，友原啓介，長谷川直人，加藤敦，足立伊佐雄
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-26870217
[Presentation] DMSO摂動効果を利用した酵素阻害剤の分子間相互作用解析2017
- Author(s)
  友原啓介，足立伊佐雄
- Organizer
  創薬懇話会2017 in 加賀
- Data Source
  KAKENHI-PROJECT-17K17750
[Presentation] DMSO摂動条件下での酵素阻害剤の分子間相互作用様式の解析2017
- Author(s)
  友原啓介，加藤敦，足立伊佐雄
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-26870217
[Presentation] 生薬抽出エキスの化学的直接誘導化2016
- Author(s)
  友原啓介
- Organizer
  平成28年度北信越有機合成化学若手の会
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-26870217
[Presentation] ピロリジン型イミノ糖を基盤とした新規GCase高親和性リガンドのデザインとファーマコジカルシャペロン効果について2016
- Author(s)
  加藤敦，山本亜里紗，友原啓介，足立伊佐雄，渡邊靖香，名取良浩，吉村祐一，中込泉，広野修一
- Organizer
  日本薬学会第１３６年会
- Place of Presentation
  横浜
- Year and Date
  2016-03-26
- Data Source
  KAKENHI-PROJECT-26870217
[Presentation] DMSO添加条件下におけるヒアルロニダーゼ阻害剤の活性部位特異性の評価2016
- Author(s)
  友原啓介，伊藤智裕，鬼形彩花，加藤敦，足立伊佐雄
- Organizer
  日本生薬学会第63回年会
- Place of Presentation
  富山
- Data Source
  KAKENHI-PROJECT-26870217
[Presentation] 多成分からなる生薬抽出エキスの化学的直接誘導化による非天然型アミノ酸等価体の一挙創製2016
- Author(s)
  古沢晃太，友原啓介，長谷川直人，伊藤智裕，加藤敦，足立伊佐雄
- Organizer
  日本生薬学会第63回年会
- Place of Presentation
  富山
- Data Source
  KAKENHI-PROJECT-26870217
[Presentation] 食後過血糖及び食後高脂血症に対する改善効果が期待される1,5-Anhydro-D-glucitolの有効性と作用メカニズムについて2015
- Author(s)
  加藤敦、渡辺優樹、辻祐太朗、友原啓介、足立伊佐雄、松上真也、竹下圭、石川文博
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸市
- Year and Date
  2015-03-27
- Data Source
  KAKENHI-PROJECT-26870217
[Presentation] イミノ糖を基盤とした副作用の少ない食後過血糖改善薬の開発研究2015
- Author(s)
  木南今日子、加藤敦、広上由季、友原啓介、中込泉、広野修一、足立伊佐雄
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸市
- Year and Date
  2015-03-27
- Data Source
  KAKENHI-PROJECT-26870217
[Presentation] イミノ糖を基盤とした次世代型グルコシルトランスフェラーゼ阻害薬の開発基礎研究2015
- Author(s)
  神守彰子、加藤敦、岩城蓮、友原啓介、足立伊佐雄
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸市
- Year and Date
  2015-03-27
- Data Source
  KAKENHI-PROJECT-26870217
[Presentation] 生薬抽出エキスの一挙誘導化によるαーアミノ酸誘導体の創製研究2015
- Author(s)
  友原啓介，伊藤智裕，長谷川直人，加藤敦，足立伊佐雄
- Organizer
  フォーラム富山「創薬」第４１回研究会
- Place of Presentation
  富山
- Year and Date
  2015-05-28
- Data Source
  KAKENHI-PROJECT-26870217
[Presentation] 副作用の少ない次世代型食後過血糖改善薬のデザイン研究2015
- Author(s)
  加藤敦，広上由季，木南今日子，友原啓介，足立伊佐雄
- Organizer
  フォーラム富山「創薬」第４１回研究会
- Place of Presentation
  富山
- Year and Date
  2015-05-28
- Data Source
  KAKENHI-PROJECT-26870217
[Presentation] 化学的摂動法を利用した複雑系生薬研究への挑戦2015
- Author(s)
  友原啓介
- Organizer
  平成２７年度富山大学若手研究者等の学術交流・発表会
- Place of Presentation
  富山
- Year and Date
  2015-09-08
- Data Source
  KAKENHI-PROJECT-26870217
[Presentation] Synthesis of alpha,alpha-disubstituted hydantoins through chemoselective derivatization of natural product extracts2015
- Author(s)
  Keisuke Tomohara, Atsushi Kato, Isao Adachi
- Organizer
  2015 International Chemical Congress of Pacific Basin Societies
- Place of Presentation
  Honolulu
- Year and Date
  2015-12-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26870217
[Presentation] 生薬からのヒスチジン脱炭酸酵素阻害物質の探索研究2015
- Author(s)
  荻原孝史，上出真由，須永百合枝，数馬恒平，紺野勝弘，友原啓介，加藤敦，足立伊佐雄
- Organizer
  日本薬学会北陸支部第１２７回例会
- Place of Presentation
  富山
- Year and Date
  2015-11-15
- Data Source
  KAKENHI-PROJECT-26870217
[Presentation] ヒアルロン酸分解酵素活性評価系におけるDMSO添加効果2015
- Author(s)
  友原啓介、伊藤智裕、加藤敦、足立伊佐雄
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸市
- Year and Date
  2015-03-28
- Data Source
  KAKENHI-PROJECT-26870217
[Presentation] 活性部位特異的なヒアルロニダーゼ阻害剤の探索2015
- Author(s)
  伊藤智裕、友原啓介、鬼形彩花、加藤敦、足立伊佐雄
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸市
- Year and Date
  2015-03-26
- Data Source
  KAKENHI-PROJECT-26870217
[Presentation] Protective effects of dietary 1,5-Anhydro-D-glucitol in diabetes and metabolic syndrome2015
- Author(s)
  Atsushi Kato, Keisuke Tomohara, Isao Adachi, Fumihiro Ishikawa, Kei Takeshita, Jacqueline Hollinshead, Robert Nash, Zilei Liu, Sarah Jenkinson, George Fleet
- Organizer
  2015 International Chemical Congress of Pacific Basin Societies
- Place of Presentation
  Honolulu
- Year and Date
  2015-12-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26870217
[Presentation] 化学的摂動効果を利用した複雑系漢方研究への挑戦2015
- Author(s)
  友原啓介
- Organizer
  2015年度北信越有機合成化学若手の会
- Place of Presentation
  富山
- Year and Date
  2015-04-04
- Data Source
  KAKENHI-PROJECT-26870217
[Presentation] C-N軸性不斉エノラートを経るアミノ酸誘導体の不斉記憶型α-アリール化の開発2014
- Author(s)
  笠松幸司、友原啓介、百武龍一、楊畔、吉村智之、川端猛夫
- Organizer
  モレキュラーキラリティー2014
- Place of Presentation
  仙台市
- Year and Date
  2014-06-07
- Data Source
  KAKENHI-PROJECT-26870217

1. Nose Takeru (10301334)

# of Collaborated Projects: 3 results

# of Collaborated Products: 13 results
2. 巣山慶太郎 (60707222)

# of Collaborated Projects: 3 results

# of Collaborated Products: 17 results
3. 前田衣織 (50311858)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results

Tomohara Keisuke 友原 啓介

TOMOHARA KEISUKE 友原 啓介

Research Projects

Research Products

Co-Researchers

Development of catalytic ammonia-Ugi reaction and synthesis of unnatural peptidesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

環境水中の有害化学物質除去に資する環境調和型温度応答性ペプチド素材の設計と応用

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Simultaneous synthesis of natural product hybrids and discovery of unexplored natural productsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of functional micro-particle capturing materials aimed at effectively utilizing natural protein resources

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of Adsorption System for Environmental Contaminants using temperature-responsive self-assembling peptides

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Interdisciplinary medicinal chemistry: Synthesis and biological evaluationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of extraction techniques for natural products and discovery of hyaluronan-degrading enzyme inhibitors from natural productsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] ちびまる子ちゃんの社会学2021

Author(s)

Total Pages

Publisher

ISBN

Data Source

[Journal Article] Ugi Adducts as Novel Anti-austerity Agents against PANC-1 Human Pancreatic Cancer Cell Line: A Rapid Synthetic Approach2023

Author(s)

Journal Title

DOI

ISSN

Year and Date

Language

Data Source

[Journal Article] Determining the Sequence Dependency of Self-Assembly of Elastin-Like Peptides Using Short Peptide Analogues with Shuffled Repetitive Sequences2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Development of Temperature-responsive Peptides by EDTA-mediated Multimerization of Short (FPGVG)n Chains2022

Author(s)

Journal Title

Data Source

[Journal Article] Metal ion scavenging activity of elastin-like peptide analogues containing a cadmium ion binding sequence2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 夾雑系生薬抽出物を基質とした天然物コネクティッド型分子群の一斉化学合成2022

Author(s)

Journal Title

DOI

ISSN

Tomohara Keisuke 友原啓介

TOMOHARA KEISUKE 友原啓介