Watanabe Toshiaki 渡部聡朗

Researcher Number	40715405
Other IDs
Affiliation (Current)	2025: 国立研究開発法人国立成育医療研究センター, 細胞医療研究部, 専門職
Affiliation (based on the past Project Information) *help	2022 – 2024: 国立研究開発法人国立成育医療研究センター, 細胞医療研究部, 専門職 2020 – 2021: 公益財団法人実験動物中央研究所, マーモセット医学生物学研究部, 研究員
Review Section/Research Field	Principal Investigator Medium-sized Section 45:Biology at organismal to population levels and anthropology, and related fields / Medium-sized Section 42:Veterinary medical science, animal science, and related fields / Basic Section 42040:Laboratory animal science-related / Transformative Research Areas, Section (III) Except Principal Investigator Transformative Research Areas, Section (III)
Keywords	Principal Investigator 霊長類 / セルトリ細胞 / 免疫不全マウス / 生殖細胞移植 / 生殖細胞 / マーモセット / 精巣 / 遺伝子改変 / 遺伝子改変動物 / 生殖工学 … More / 精子形成 / ヒト / DNAメチル化確立 / 不妊 / DTR / ノックインマウス / 培養 / 発生工学 / 幹細胞 / 細胞分裂 / PIWIL4 / ウイルス / 移植前選抜 / ノックイン / 初期胚 / 精子幹細胞 / 始原生殖細胞 / 配偶子形成 / 自家移植 / DNA メチル化 / 生殖細胞発生 / 分化誘導 / iPS細胞 / mRNA transfection / 始原生殖細胞様細胞 … More Except Principal Investigator 霊長類 / 次世代 / 生殖細胞 / 精子形成 / エピゲノム / 変異 / ゲノム / 幹細胞 / 生殖 Less

ヒト雄性生殖細胞におけるDNAメチル化確立の解析Principal Investigator
- Principal Investigator
  
  渡部聡朗
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Fund for the Promotion of Joint International Research (International Collaborative Research)
- Review Section
  
  Medium-sized Section 45:Biology at organismal to population levels and anthropology, and related fields
- Research Institution
  National Center for Child Health and Development
genome stability for the next generation
- Principal Investigator
  
  中馬新一郎
- Project Period (FY)
  2023 – 2027
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Kyoto University
Constructing primate testes in mice by replacing testicular cellsPrincipal Investigator
- Principal Investigator
  
  渡部聡朗
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Pioneering)
- Review Section
  
  Medium-sized Section 42:Veterinary medical science, animal science, and related fields
- Research Institution
  National Center for Child Health and Development
Generation of genetically modified primates using cultured germ cellsPrincipal Investigator
- Principal Investigator
  
  Watanabe Toshiaki
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (B)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  National Center for Child Health and Development
  Central Institute for Experimental Animals
Development of novel techniques for generation of genome engineering marmosetsPrincipal Investigator
- Principal Investigator
  
  Watanabe Toshiaki
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 42040:Laboratory animal science-related
- Research Institution
  National Center for Child Health and Development
  Central Institute for Experimental Animals

All 2024 2023 2022 2021 2020

All Journal Article Presentation

[Journal Article] Germ Cell Depletion using HSV1-TK in Mouse Testes2024
- Author(s)
  Constance Dollet, Miyuki Shindo, Shun Takahashi, Satomi Kuramochi-Miyagawa, Tomoo Eto, and Toshiaki Watanabe
- Journal Title
  
  Research Square
  
  Volume: -
- DOI
  10.21203/rs.3.rs-4270256/v1
- Open Access
- Data Source
  KAKENHI-PROJECT-22K18356
[Journal Article] mRNA-based generation of marmoset PGCLCs capable of differentiation into gonocyte-like cells2023
- Author(s)
  Kubiura-Ichimaru Musashi、Penfold Christopher、Kojima Kazuaki、Dollet Constance、Yabukami Haruka、Semi Katsunori、Takashima Yasuhiro、Boroviak Thorsten、Kawaji Hideya、Woltjen Knut、Minoda Aki、Sasaki Erika、Watanabe Toshiaki
- Journal Title
  
  Stem Cell Reports
  
  Volume: 18 Issue: 10 Pages: 1987-2002
- DOI
  10.1016/j.stemcr.2023.08.006
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-23H04953, KAKENHI-PROJECT-22H04925
[Journal Article] mRNA-based generation of marmoset PGCLCs capable of differentiation into gonocyte-like cells2022
- Author(s)
  Kubiura-Ichimaru Musashi、Penfold Christopher、Kojima Kazuaki、Dollet Constance、Yabukami Haruka、Semi Katsunori、Takashima Yasuhiro、Boroviak Thorsten、Kawaji Hideya、Woltjen Knut、Minoda Aki、Sasaki Erika、Watanabe Toshiaki
- Journal Title
  
  BioRxiv
  
  Volume: N/A
- DOI
  10.1101/2022.09.20.508677
- Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K18356, KAKENHI-ORGANIZER-20H05760, KAKENHI-PLANNED-20H05762, KAKENHI-PLANNED-20H05764, KAKENHI-PROJECT-20H03177, KAKENHI-PROJECT-21K19189
[Journal Article] Establishment of an integrated automated embryonic manipulation system for producing genetically modified mice2021
- Author(s)
  Eto Tomoo、Ueda Hiroki、Ito Ryoji、Takahashi Tsukasa、Watanabe Toshiaki、Goto Motohito、Sotomaru Yusuke、Tanaka Nobuaki、Takahashi Riichi
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 15770-15770
- DOI
  10.1038/s41598-021-91148-9
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-20H05764, KAKENHI-PROJECT-19H01056, KAKENHI-PROJECT-20K06477, KAKENHI-PROJECT-21K06005, KAKENHI-PROJECT-20H03177
[Journal Article] Efficient Induction of Primate iPS Cells Using a Combination of RNA Transfection and Chemical Compounds2021
- Author(s)
  Watanabe Toshiaki、Sasaki Erika
- Journal Title
  
  Methods in Molecular Biology
  
  Volume: 1 Pages: 10-10
- DOI
  10.1007/7651_2021_373
- ISBN
  9781071621189, 9781071621196
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-20H05760, KAKENHI-PLANNED-20H05764, KAKENHI-PROJECT-20H03177
[Presentation] Establishment of DNA methylation in primate germ cell development2023
- Author(s)
  渡部聡朗
- Organizer
  日本分子生物学会年会
- Data Source
  KAKENHI-PLANNED-23H04953
[Presentation] マーモセット精巣における新たな霊長類精子幹細胞系の解明2023
- Author(s)
  渡部聡朗
- Organizer
  マーモセット研究会
- Data Source
  KAKENHI-PLANNED-23H04953
[Presentation] 霊長類生殖細胞におけるDNAメチル化確立2023
- Author(s)
  渡部聡朗
- Organizer
  有性生殖細胞研究会
- Data Source
  KAKENHI-PLANNED-23H04953
[Presentation] 多能性幹細胞からのマーモセット初期生殖細胞発生系の構築2023
- Author(s)
  渡部聡朗
- Organizer
  マーモセット研究会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03177
[Presentation] 多能性幹細胞からのマーモセット初期生殖細胞発生系の構築2023
- Author(s)
  渡部聡朗
- Organizer
  マーモセット研究会
- Invited
- Data Source
  KAKENHI-PLANNED-20H05764
[Presentation] 多能性幹細胞からのマーモセット初期生殖細胞発生系の構築2023
- Author(s)
  渡部聡朗
- Organizer
  マーモセット研究会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K18356
[Presentation] 霊長類コモンマーモセット及びカニクイザルの雄性生殖細胞における DNA メチル化確立過程のシングルセル解析2022
- Author(s)
  小島一晃、近藤洋介、小原実穂、Dollet Constance、山海直、仲木竜、渡部聡朗
- Organizer
  日本実験動物学会総会
- Data Source
  KAKENHI-PLANNED-20H05764
[Presentation] Marmoset germ cell differentiation from pluripotent cells2022
- Author(s)
  Toshiaki Watanabe
- Organizer
  55th Society for the Study of Reproduction annual conference
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-20H05764
[Presentation] Marmoset germ cell differentiation from pluripotent cells2022
- Author(s)
  Toshiaki Watanabe
- Organizer
  55th Society for the Study of Reproduction annual conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03177
[Presentation] mRNA-based generation of marmoset PGCLCs capable of differentiation into gonocyte-like cells2022
- Author(s)
  Kubiura-Ichimaru M. and Watanabe T.
- Organizer
  Totipotency and germ cell development
- Data Source
  KAKENHI-PROJECT-20H03177
[Presentation] Primates have a distinct spermatogonial stem cell system to maintain the genomic integrity2022
- Author(s)
  渡部聡朗
- Organizer
  マーモセット研究会
- Data Source
  KAKENHI-PLANNED-20H05764
[Presentation] Marmoset germ cell differentiation from pluripotent cells2022
- Author(s)
  Toshiaki Watanabe
- Organizer
  55th Society for the Study of Reproduction annual conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K18356
[Presentation] 霊長類コモンマーモセット及びカニクイザルの雄性生殖細胞における DNA メチル化確立過程のシングルセル解析2022
- Author(s)
  小島一晃、近藤洋介、小原実穂、Dollet Constance、山海直、仲木竜、渡部聡朗
- Organizer
  日本実験動物学会
- Data Source
  KAKENHI-PROJECT-22K18356
[Presentation] mRNA-based generation of marmoset PGCLCs capable of differentiation into gonocyte-like cells2022
- Author(s)
  Kubiura-Ichimaru M. and Watanabe T.
- Organizer
  Totipotency and germ cell development
- Data Source
  KAKENHI-PROJECT-22K18356
[Presentation] Primates have a distinct spermatogonial stem cell system to maintain the genomic integrity2022
- Author(s)
  渡部聡朗
- Organizer
  日本マーモセット研究会
- Data Source
  KAKENHI-PROJECT-20H03177
[Presentation] 霊長類コモンマーモセット及びカニクイザルの雄性生殖細胞における DNA メチル化確立過程のシングルセル解析2022
- Author(s)
  小島一晃、近藤洋介、小原実穂、Dollet Constance、山海直、仲木竜、渡部聡朗
- Organizer
  日本実験動物学会
- Data Source
  KAKENHI-PROJECT-20H03177
[Presentation] Genomic and epigenomic integrity controls during primate male germ cell development2021
- Author(s)
  渡部聡朗
- Organizer
  日本分子生物学会
- Data Source
  KAKENHI-PROJECT-20H03177
[Presentation] 霊長類マーモセット雄性生殖幹細胞におけるPIWI-piRNA機構の解析2021
- Author(s)
  小島一晃, 藪上春香, 圦本晃海, 峰重隆幸, 井上貴史, 喜多善亮, 黒滝陽子, 下郡智美, 川路英哉, 蓑田亜希子, 佐々木えりか, 渡部聡朗
- Organizer
  日本マーモセット研究会
- Data Source
  KAKENHI-PROJECT-20H03177
[Presentation] 霊長類マーモセット雄性生殖細胞におけるDNAメチル化確立過程のシングルセル解析2021
- Author(s)
  小島一晃, 近藤洋介 ,圦本晃海, 向笠圭亮, 井上貴史, 黒滝陽子, 佐々木えりか, 仲木竜, 渡部聡朗
- Organizer
  日本分子生物学会
- Data Source
  KAKENHI-PROJECT-20H03177
[Presentation] Genomic and epigenomic integrity controls during primate male germ cell development2021
- Author(s)
  渡部聡朗
- Organizer
  分子生物学会
- Data Source
  KAKENHI-PLANNED-20H05764
[Presentation] 霊長類マーモセット雄性生殖幹細胞におけるPIWI-piRNA機構の解析2021
- Author(s)
  小島一晃, 藪上春香, 圦本晃海, 峰重隆幸, 井上貴史, 喜多善亮, 黒滝陽子, 下郡智美, 川路英哉, 蓑田亜希子, 佐々木えりか, 渡部聡朗
- Organizer
  日本マーモセット研究会
- Data Source
  KAKENHI-PLANNED-20H05764
[Presentation] マーモセット iPS 細胞からの始原生殖細胞様細胞の誘導2021
- Author(s)
  渡部聡朗、Christopher Penfold、蝉克憲、岩崎師壽江、篠原晴香、髙島康弘、Thorsten Boroviak、Knut Woltjen、佐々木えりか
- Organizer
  日本マーモセット研究会
- Data Source
  KAKENHI-PROJECT-20H03177
[Presentation] マーモセット iPS 細胞からの始原生殖細胞様細胞の誘導2021
- Author(s)
  渡部聡朗、Christopher Penfold、蝉克憲、岩崎師壽江、篠原晴香、髙島康、Thorsten Boroviak、Knut Woltjen、佐々木えりか
- Organizer
  日本マーモセット研究会
- Data Source
  KAKENHI-PLANNED-20H05764
[Presentation] 霊長類マーモセット雄性生殖細胞におけるDNAメチル化確立過程のシングルセル解析2021
- Author(s)
  小島一晃, 近藤洋介 ,圦本晃海, 向笠圭亮, 井上貴史, 黒滝陽子, 佐々木えりか, 仲木竜, 渡部聡朗
- Organizer
  日本分子生物学会
- Data Source
  KAKENHI-PLANNED-20H05764
[Presentation] Analysis of PIWI-piRNA mechanism in primate marmosets male germline stem cells2020
- Author(s)
  小島一晃, 藪上春香, 圦本晃海, 峰重隆幸, 井上貴史, 喜多善亮, 黒滝陽子, 下郡智美, 川路英哉, 蓑田亜希子, 佐々木えりか, 渡部聡朗
- Organizer
  日本分子生物学会
- Data Source
  KAKENHI-PLANNED-20H05764
[Presentation] Analysis of PIWI-piRNA mechanism in primate marmosets male germline stem cells2020
- Author(s)
  小島一晃, 藪上春香, 圦本晃海, 峰重隆幸, 井上貴史, 喜多善亮, 黒滝陽子, 下郡智美, 川路英哉, 蓑田亜希子, 佐々木えりか, 渡部聡朗
- Organizer
  日本分子生物学会
- Data Source
  KAKENHI-PROJECT-20H03177

1. 山海直 (80300937)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
2. 中馬新一郎 (20378889)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 富澤信一 (00704628)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 首浦武作志 (20827977)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Watanabe Toshiaki 渡部 聡朗

Research Projects

Research Products

Co-Researchers

ヒト雄性生殖細胞におけるDNAメチル化確立の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

genome stability for the next generation

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Constructing primate testes in mice by replacing testicular cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Generation of genetically modified primates using cultured germ cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of novel techniques for generation of genome engineering marmosetsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Germ Cell Depletion using HSV1-TK in Mouse Testes2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] mRNA-based generation of marmoset PGCLCs capable of differentiation into gonocyte-like cells2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] mRNA-based generation of marmoset PGCLCs capable of differentiation into gonocyte-like cells2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Establishment of an integrated automated embryonic manipulation system for producing genetically modified mice2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Efficient Induction of Primate iPS Cells Using a Combination of RNA Transfection and Chemical Compounds2021

Author(s)

Journal Title

DOI

ISBN

Data Source

[Presentation] Establishment of DNA methylation in primate germ cell development2023

Author(s)

Organizer

Data Source

[Presentation] マーモセット精巣における新たな霊長類精子幹細胞系の解明2023

Author(s)

Organizer

Data Source

[Presentation] 霊長類生殖細胞におけるDNAメチル化確立2023

Author(s)

Organizer

Data Source

[Presentation] 多能性幹細胞からのマーモセット初期生殖細胞発生系の構築2023

Author(s)

Organizer

Data Source

[Presentation] 多能性幹細胞からのマーモセット初期生殖細胞発生系の構築2023

Author(s)

Organizer

Data Source

Watanabe Toshiaki 渡部聡朗

[Presentation] 霊長類コモンマーモセット及びカニクイザルの雄性生殖細胞における DNA メチル化確立過程のシングルセル解析2022