Nakano Dan 中野暖

Researcher Number	40723987
Other IDs
Affiliation (Current)	2025: 久留米大学, 医学部, 助教
Affiliation (based on the past Project Information) *help	2019 – 2025: 久留米大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 53010:Gastroenterology-related / Basic Section 50010:Tumor biology-related Except Principal Investigator Basic Section 53010:Gastroenterology-related
Keywords	Principal Investigator 電子伝達系 / 脂肪酸代謝 / 肝臓癌 / SGLT2阻害剤 / SGLT2 / ミトコンドリア / プリン、ピリミジン経路 / 背景肝 / ケモカイン / 肝癌 / 糖尿病薬 / 肝細胞癌 … More Except Principal Investigator … More マイオカイン / 肝硬変 / 代謝異常関連脂肪性肝障害 / 肝がん / レジスタンス運動 / 肝線維化 / 脂肪肝 / 肝細胞癌 / デコリン / 細胞増殖抑制 / 細胞周期 / decorin / 非アルコール性脂肪肝炎 / 細胞増殖 / ワールブルグ効果 / ペントースリン酸経路 / 運動 / 肝癌 / Decorin Less

SGLT2阻害剤による肝癌の糖鎖と微小環境への影響Principal Investigator
- Principal Investigator
  
  中野暖
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Kurume University
レジスタンス運動誘発マイオカインによる肝発がん抑制効果の機序
- Principal Investigator
  
  川口巧
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Kurume University
SGLT2阻害剤の肝癌微小環境への影響Principal Investigator
- Principal Investigator
  
  中野暖
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Kurume University
Effects of myokine decorin on NASH-related hepatocellular carichoma
- Principal Investigator
  
  Kawaguchi Takumi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Kurume University
Effect of SGLT2 inhibitor for hepatocellular carcinomaPrincipal Investigator
- Principal Investigator
  
  Nakano Dan
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Kurume University

All 2023 2022 2021 2020 2019

All Journal Article Presentation

[Journal Article] A low-intensity 10-min resistance exercise program that ameliorated hepatic fibrosis indices and altered G-CSF/IP-10/PDGF-BB in a patient with nonalcoholic fatty liver disease: A case report.2023
- Author(s)
  Hashida Ryuki、Nakano Dan、Matsuse Hiroo、Yoshio Sachiyo、Tsutsumi Tsubasa、Kawaguchi Machiko、Koya Shunji、Hirota Keisuke、Tajima Hiroshi、Sumida Yoshio、Kanto Tatsuya、Kawaguchi Takumi、Hiraoka Koji
- Journal Title
  
  JGH Open
  
  Volume: 7 Issue: 3 Pages: 231-234
- DOI
  10.1002/jgh3.12876
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08395, KAKENHI-PROJECT-22K17667
[Journal Article] Effects of SGLT2 inhibitor on tumor-releasing chemokines/cytokines in Hep3B and Huh7 cells2022
- Author(s)
  Nakano D, Kawaguchi T, Tsutsumi T, Hayakawa M, Yoshio S, Koga H, Torimura T.
- Journal Title
  
  JGH Open
  
  Volume: 17 Issue: 4 Pages: 270-273
- DOI
  10.1002/jgh3.12730
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K17446, KAKENHI-PROJECT-22K16059
[Journal Article] Hepatic expression of sodium?glucose cotransporter 2 (SGLT2) in patients with chronic liver disease2022
- Author(s)
  Nakano Dan、Akiba Jun、Tsutsumi Tsubasa、Kawaguchi Machiko、Yoshida Takafumi、Koga Hironori、Kawaguchi Takumi
- Journal Title
  
  Medical Molecular Morphology
  
  Volume: 55 Issue: 4 Pages: 304-315
- DOI
  10.1007/s00795-022-00334-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K17446
[Journal Article] Effects of interleukin-17 inhibitors on hepatic fibrosis index in patients with psoriasis and metabolic dysfunction-associated fatty liver disease: Directed acyclic graphs2022
- Author(s)
  Takamura Saori、Teraki Yuichi、Katayama Eri、Kawaguchi Takumi、Kawaguchi Machiko、Nakano Dan、Tsutsumi Tsubasa、Nagoshi Sumiko、Nakama Takekuni、Torimura Takuji
- Journal Title
  
  Clinical and Molecular Hepatology
  
  Volume: 28 Issue: 2 Pages: 269-272
- DOI
  10.3350/cmh.2022.0040
- Data Source
  KAKENHI-PROJECT-20K08395
[Journal Article] Metabolic dysfunction‐associated fatty liver disease directly related to liver fibrosis independent of insulin resistance, hyperlipidemia, and alcohol intake in morbidly obese patients2022
- Author(s)
  Inamine Susumu、Kage Masayoshi、Akiba Jun、Kawaguchi Takumi、Yoshio Sachiyo、Kawaguchi Machiko、Nakano Dan、Tsutsumi Tsubasa、Hashida Ryuki、Oshiro Kouichi
- Journal Title
  
  Hepatology Research
  
  Volume: 52 Issue: 10 Pages: 841-858
- DOI
  10.1111/hepr.13808
- Data Source
  KAKENHI-PROJECT-20K08395
[Journal Article] Non-Obese MAFLD Is Associated with Colorectal Adenoma in Health Check Examinees: A Multicenter Retrospective Study2021
- Author(s)
  Fukunaga Shuhei、Nakano Dan、Kawaguchi Takumi、Eslam Mohammed、Ouchi Akihiro、Nagata Tsutomu、Kuroki Hidefumi、Kawata Hidemichi、Abe Hirohiko、Nouno Ryuichi、Kawaguchi Koutaro、George Jacob、Mitsuyama Keiichi、Torimura Takuji
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 22 Issue: 11 Pages: 5462-5462
- DOI
  10.3390/ijms22115462
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08395
[Journal Article] Association between Activity and Brain-Derived Neurotrophic Factor in Patients with Non-Alcoholic Fatty Liver Disease: A Data-Mining Analysis2021
- Author(s)
  Hashida Ryuki、Nakano Dan、Yamamura Sakura、Kawaguchi Takumi、Tsutsumi Tsubasa、Matsuse Hiroo、Takahashi Hirokazu、Gerber Lynn、Younossi Zobair M.、Torimura Takuji
- Journal Title
  
  Life
  
  Volume: 11 Issue: 8 Pages: 799-799
- DOI
  10.3390/life11080799
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08395
[Journal Article] Effects of a low‐intensity resistance exercise program on serum miR‐630, miR‐5703, and Fractalkine/CX3CL1 expressions in subjects with No exercise habits: A preliminary study2021
- Author(s)
  Hashida Ryuki、Matsuse Hiroo、Kawaguchi Takumi、Yoshio Sachiyo、Bekki Masafumi、Iwanaga Sohei、Sugimoto Takahiro、Hara Koji、Koya Shunji、Hirota Keisuke、Nakano Dan、Tsutsumi Tsubasa、Kanto Tatsuya、Torimura Takuji、Shiba Naoto
- Journal Title
  
  Hepatology Research
  
  Volume: 51 Issue: 7 Pages: 823-833
- DOI
  10.1111/hepr.13670
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08395, KAKENHI-PROJECT-21K08020
[Presentation] SGLT2 Inhibitor Suppressed Proliferation of Hepatoma Cell via Regulation of Metabolic Reprograming and Tumor-releasing Chemokines: Malti-omics and Multiplex Analysis.2023
- Author(s)
  5)Nakano D
- Organizer
  The 3rd JSH International Liver Conference.
- Data Source
  KAKENHI-PROJECT-22K16059
[Presentation] 肝癌組織におけるSGLT2の発現とSGLT2阻害剤が肝癌細胞の増殖に及ぼす影響： Multi-omics/Multiplex解析.2023
- Author(s)
  中野　暖
- Organizer
  第109回日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-22K16059
[Presentation] SGLT2阻害剤が肝細胞癌の増殖と代謝に及ぼす影響～Multi-OmicsおよびMultiplexを用いた解析～2023
- Author(s)
  中野　暖
- Organizer
  第55回日本臨床分子形態学会総会・学術集会.
- Data Source
  KAKENHI-PROJECT-22K16059
[Presentation] がんリハビリテーションが肝癌患者の予後におよぼす影響2022
- Author(s)
  川口　巧、橋田竜騎、中野　暖、堤翼、松瀬博夫、平岡弘二
- Organizer
  第29回日本門脈圧亢進症学会総会
- Data Source
  KAKENHI-PROJECT-20K08395
[Presentation] 48)SGLT2 Inhibitor Suppressed Proliferation of Hepatocellular Carcinoma via Regulation of Metabolic Reprograming and Tumor-Releasing Chemokines/Cytokines: a Metabolomic and Proteomic Analysis2022
- Author(s)
  Nakano Dan
- Organizer
  The Liver Meeting Digital Experience 2022（The 73th Annual Meeting of the American Association for the Study of Liver Diseases (AASLD)
- Data Source
  KAKENHI-PROJECT-19K17446
[Presentation] SGLT2 Inhibitor Suppressed Proliferation of Hepatocellular Carcinoma via Regulation of Metabolic Reprogramming and Tumor- Releasing Chemokines/Cytokines: A Metabolomic and Proteomic Analysis2022
- Author(s)
  Nakano Dan
- Organizer
  APASL Oncology 2022
- Data Source
  KAKENHI-PROJECT-22K16059
[Presentation] SGLT2阻害剤がヒト肝癌細胞株の増殖と代謝におよぼす影響2022
- Author(s)
  中野　暖
- Organizer
  JDDW　2022
- Data Source
  KAKENHI-PROJECT-19K17446
[Presentation] SGLT2阻害剤がNASHマウスモデルの肝癌の増殖に及ぼす影響：メタボロームとプロテオームを用いたMulti-omics 解析2022
- Author(s)
  中野　暖
- Organizer
  第58回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-22K16059
[Presentation] SGLT2阻害剤がヒト肝癌細胞株の増殖と代謝におよぼす影響2022
- Author(s)
  中野　暖
- Organizer
  JDDW　2022
- Data Source
  KAKENHI-PROJECT-22K16059
[Presentation] 40)SGLT2阻害剤がNASHマウスモデルの肝癌の増殖に及ぼす影響：メタボロームとプロテオームを用いたMulti-omics 解析2022
- Author(s)
  中野　暖
- Organizer
  第58回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-19K17446
[Presentation] SGTL2 Inhibitor Suppressed Proliferation of Hepatocellular Carcinoma via Regulation of Metabolic Reprograming and Tumor- Releasing Chemokines/Cytokines: a Metabolomic and Proteomic Analysis2022
- Author(s)
  Nakano D
- Organizer
  The Liver Meeting Digital Experience 2022（The 73th Annual Meeting of the American Association for the Study of Liver Diseases (AASLD)）
- Data Source
  KAKENHI-PROJECT-22K16059
[Presentation] 42)SGLT2 Inhibitor Suppressed Proliferation of Hepatocellular Carcinoma via Regulation of Metabolic Reprogramming and Tumor-Releasing Chemokines/Cytokines: A Metabolomic and Proteomic Analysis2022
- Author(s)
  Nakano Dan
- Organizer
  APASL Oncology 2022
- Data Source
  KAKENHI-PROJECT-19K17446
[Presentation] SGLT2 阻害剤が肝細胞癌の増殖に及ぼす影響：メタボロームとプロテオームを用いたMulti-omics 解析2021
- Author(s)
  中野　暖
- Organizer
  第57回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-19K17446
[Presentation] マイオカインdecorinが肝がん患者のサルコペニアと予後におよぼす影響2021
- Author(s)
  中野　暖、川口　巧、鳥村　拓司
- Organizer
  第25回日本肝臓学会大会
- Data Source
  KAKENHI-PROJECT-20K08395
[Presentation] マイオカインdecorinが肝がん患者のサルコペニアと予後におよぼす影響2021
- Author(s)
  中野　暖
- Organizer
  29th JDDW（第25回日本肝臓学会大会・第63回日本消化器病学会大会・第19回日本消化器外科学会大会)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K17446
[Presentation] "SGLT2 INHIBITOR ALTERED METABOLIC REPROGRAMMING AND SUPPRESSED PROLIFERATION OF HEPATOCELLULAR CARCINOMA: A METABOLOMIC AND PROTEOMIC ANALYSIS"2021
- Author(s)
  Nakano D
- Organizer
  The Liver Meeting Digital Experience 2021（The 72th Annual Meeting of the American Association for the Study of Liver Diseases (AASLD)）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K17446
[Presentation] An Impact of Albumin-Bilirubin (ALBI) Score on Pulmonary Arterial Pressure in Patients with Chronic Liver Disease with Porto-pulmonary Hypertension (PoPH): A Data-mining Analysis2021
- Author(s)
  Takumi Kawaguchi, Akihiro Honda, Yoichi Sugiyama, Dan Nakano, Tsubsa Tsutsumi, Nobuhiro Tahara, Takuji Torimura, Yoshihiro Fukumoto
- Organizer
  The Liver Meeting 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08395
[Presentation] SGLT2阻害剤が肝細胞癌の増殖と代謝に及ぼす影響; Multi-omicsを用いた解析2021
- Author(s)
  中野　暖
- Organizer
  第53回日本臨床分子形態学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-19K17446
[Presentation] SGLT2阻害剤が肝細胞癌の増殖と代謝に及ぼす影響2020
- Author(s)
  中野　暖
- Organizer
  日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-19K17446
[Presentation] SGLT2阻害剤がNASH関連肝癌マウスモデルの腫瘍増殖と代謝に及ぼす影響2020
- Author(s)
  中野　暖
- Organizer
  日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-19K17446
[Presentation] SGLT2阻害剤が肝細胞癌の増殖と代謝に及ぼす影響2019
- Author(s)
  中野　暖
- Organizer
  日本臨床分子形態学会
- Data Source
  KAKENHI-PROJECT-19K17446
[Presentation] SGLT2阻害剤が肝細胞癌の増殖と代謝に及ぼす影響2019
- Author(s)
  中野　暖
- Organizer
  日本消化器病学会
- Data Source
  KAKENHI-PROJECT-19K17446
[Presentation] SGLT2阻害剤が肝細胞癌の増殖と代謝に及ぼす影響2019
- Author(s)
  中野　暖
- Organizer
  JDDW2019
- Data Source
  KAKENHI-PROJECT-19K17446
[Presentation] SGLT2阻害剤が肝細胞癌の増殖と代謝に及ぼす影響2019
- Author(s)
  中野　暖
- Organizer
  肝臓と糖尿病、代謝研究会
- Data Source
  KAKENHI-PROJECT-19K17446
[Presentation] SGLT2 inhibitor Altered Metabolic Reprograming and Suppressed Proliferatoin of Hepatocellular Carcinoma2019
- Author(s)
  中野　暖
- Organizer
  AASLD
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K17446
[Presentation] SGLT2阻害剤が肝細胞癌の増殖と代謝に及ぼす影響2019
- Author(s)
  中野　暖
- Organizer
  九州メタボローム研究会
- Data Source
  KAKENHI-PROJECT-19K17446

1. Kawaguchi Takumi (00320177)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
2. 橋田竜騎 (40754841)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
3. 堤翼 (60624103)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Nakano Dan 中野 暖

Research Projects

Research Products

Co-Researchers

SGLT2阻害剤による肝癌の糖鎖と微小環境への影響Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

レジスタンス運動誘発マイオカインによる肝発がん抑制効果の機序

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

SGLT2阻害剤の肝癌微小環境への影響Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Effects of myokine decorin on NASH-related hepatocellular carichoma

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Effect of SGLT2 inhibitor for hepatocellular carcinomaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] A low-intensity 10-min resistance exercise program that ameliorated hepatic fibrosis indices and altered G-CSF/IP-10/PDGF-BB in a patient with nonalcoholic fatty liver disease: A case report.2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Effects of SGLT2 inhibitor on tumor-releasing chemokines/cytokines in Hep3B and Huh7 cells2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Hepatic expression of sodium?glucose cotransporter 2 (SGLT2) in patients with chronic liver disease2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Effects of interleukin-17 inhibitors on hepatic fibrosis index in patients with psoriasis and metabolic dysfunction-associated fatty liver disease: Directed acyclic graphs2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Metabolic dysfunction‐associated fatty liver disease directly related to liver fibrosis independent of insulin resistance, hyperlipidemia, and alcohol intake in morbidly obese patients2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Non-Obese MAFLD Is Associated with Colorectal Adenoma in Health Check Examinees: A Multicenter Retrospective Study2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Association between Activity and Brain-Derived Neurotrophic Factor in Patients with Non-Alcoholic Fatty Liver Disease: A Data-Mining Analysis2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Effects of a low‐intensity resistance exercise program on serum miR‐630, miR‐5703, and Fractalkine/CX3CL1 expressions in subjects with No exercise habits: A preliminary study2021

Author(s)

Journal Title

DOI

Data Source

[Presentation] SGLT2 Inhibitor Suppressed Proliferation of Hepatoma Cell via Regulation of Metabolic Reprograming and Tumor-releasing Chemokines: Malti-omics and Multiplex Analysis.2023

Author(s)

Organizer

Data Source

[Presentation] 肝癌組織におけるSGLT2の発現とSGLT2阻害剤が肝癌細胞の増殖に及ぼす影響： Multi-omics/Multiplex解析.2023

Author(s)

Nakano Dan 中野暖

[Presentation] がんリハビリテーションが肝癌患者の予後におよぼす影響2022