Hayashi Takanori 林孝典

Researcher Number	40724315
Other IDs
Affiliation (Current)	2025: 藤田医科大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2025: 藤田医科大学, 医学部, 准教授 2018 – 2024: 藤田医科大学, 医学部, 講師 2017: 藤田保健衛生大学, 医学部, 講師
Review Section/Research Field	Principal Investigator Basic Section 54040:Metabolism and endocrinology-related / Endocrinology Except Principal Investigator Basic Section 56040:Obstetrics and gynecology-related / Basic Section 49020:Human pathology-related / Basic Section 55010:General surgery and pediatric surgery-related / Basic Section 55020:Digestive surgery-related
Keywords	Principal Investigator ニューロエストロゲン / エストロゲン / 母性 / アロマターゼ / 養育 / 摂食 / 女性医学 / MC4R / ニューロステロイド / 食欲 … More Except Principal Investigator … More エストロゲン / ニューロエストロゲン / エストロゲン受容体β / 右側 / 高齢者 / 結腸癌 / アロマターゼ / 漢方 / 糖 / 女性医学 / 食欲 / 患者腫瘍組織移植モデル / 大腸癌 / エストロゲン濃度 / 右側癌 / 閉経後女性 / ミスマッチ修復タンパク質 / ESR2 CA repeat多型 / 大腸がんモデル / がん幹細胞 / ER / 大腸がん / 分化転換 / 卵巣がん / 腫瘍間質 / がん / 脂肪細胞 / Akt / アロマターゼ阻害薬 / Rab / 薬剤耐性 / CDK4/6 / パルボシクリブ / 乳がん / 難治性乳がん治療 Less

ニューロエストロゲンの作用を基盤とした育児放棄の治療標的探索Principal Investigator
- Principal Investigator
  
  林孝典
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  Fujita Health University
糖質がもたらす情動変化にニューロエストロゲンがもたらす影響
- Principal Investigator
  
  西尾永司
- Project Period (FY)
  2025 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Fujita Health University
大腸癌のエストロゲン応答多様性の背景にある分子機構の解明
- Principal Investigator
  
  本間尚子
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  Toho University
大腸癌に対するエストロゲン作用の多様性についての包括的研究
- Principal Investigator
  
  本間尚子
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  Toho University
遺伝子改変マウスを用いたニューロエストロゲンが摂食行動に与える影響
- Principal Investigator
  
  西尾永司
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Fujita Health University
Study of colorectal cancer suppression mechanism by estrogen using the new colorectal cancer animal model
- Principal Investigator
  
  Satou Harunobu
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Fujita Health University
Neuroestrogens on neglect and investigating molecular mechanisms of action.Principal Investigator
- Principal Investigator
  
  Hayashi Takanori
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  Fujita Health University
Overcoming Molecular Targeted Drug Resistance in Aromatase Inhibitor-Resistant Breast Cancer.
- Principal Investigator
  
  Hikichi Masahiro
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Fujita Health University
integrated analysis of mechanisms promoting tumorigenesis by adipocyte
- Principal Investigator
  
  Maeda Masao
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Fujita Health University
Elucidation of the function of neuroestrogen on feeding behavior.Principal Investigator
- Principal Investigator
  
  Hayashi Takanori
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Endocrinology
- Research Institution
  Fujita Health University

All 2021 2020 2019 2018 2017

All Journal Article Presentation

[Journal Article] Upregulation of CIP2A in estrogen depletion‐resistant breast cancer cells treated with low‐dose everolimus2020
- Author(s)
  Nishio Eiji、Hayashi Takanori、Akaza Mao、Hisatomi Yukiko、Hikichi Masahiro、Fujii Takuma、Utsumi Toshiaki、Harada Nobuhiro、Shimono Yohei
- Journal Title
  
  FEBS Open Bio
  
  Volume: 10 Issue: 10 Pages: 2072-2080
- DOI
  10.1002/2211-5463.12956
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09084, KAKENHI-PROJECT-20K09681, KAKENHI-PROJECT-18K07231
[Journal Article] miR-221 Targets QKI to Enhance the Tumorigenic Capacity of Human Colorectal Cancer Stem Cells.2019
- Author(s)
  Mukohyama J, Isobe T, Hu Q, Hayashi T, Watanabe T, Maeda M, Yanagi H, Qian X, Yamashita K, Minami H, Mimori K, Sahoo D, Kakeji Y, Suzuki A, Dalerba P, Shimono Y.
- Journal Title
  
  Cancer Research
  
  Volume: 79 Issue: 20 Pages: 5151-5158
- DOI
  10.1158/0008-5472.can-18-3544
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07231, KAKENHI-PROJECT-19K17831, KAKENHI-PROJECT-16H05415, KAKENHI-PROJECT-17K16172, KAKENHI-PROJECT-17K16555
[Journal Article] Lack of association of ovariectomy-induced obesity with overeating and the reduction of physical activities.2019
- Author(s)
  Nishio E, Hayashi T, Nakatani M, Aida N, Suda R, Fujii T, Wakatsuki T, Honda S, Harada N, Shimono Y.
- Journal Title
  
  Biochemistry and Biophysics Reports
  
  Volume: 20 Pages: 100671-100671
- DOI
  10.1016/j.bbrep.2019.100671
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07231, KAKENHI-PROJECT-17K16172
[Journal Article] A Hypoglycemia-inducing Giant Borderline Phyllodes Tumor Secreting High-molecular-weight Insulin-Like Growth Factor II: Immunohistochemistry and a Western Blot Analysis2018
- Author(s)
  Masahiro Hikichi, Yuka Kiriyama, Takanori Hayashi, Kaori Ushimado, Naomi Kobayashi, Makoto Urano, Makoto Kuroda, Toshiaki Utsumi
- Journal Title
  
  Intern. Med.
  
  Volume: 57 Issue: 2 Pages: 237-241
- DOI
  10.2169/internalmedicine.9287-17
- NAID
  130006309182
- ISSN
  0918-2918, 1349-7235
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K16172
[Journal Article] Forskolin increases the effect of everolimus on aromatase inhibitor-resistant breast cancer cells2018
- Author(s)
  Hayashi Takanori、Hikichi Masahiro、Yukitake Jun、Wakatsuki Toru、Nishio Eiji、Utsumi Toshiaki、Harada Nobuhiro
- Journal Title
  
  Oncotarget
  
  Volume: 9 Issue: 34 Pages: 23451-23461
- DOI
  10.18632/oncotarget.25217
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K16172
[Journal Article] Estradiol suppresses phosphorylation of ERα serine 167 through upregulation of PP2A in breast cancer cells2017
- Author(s)
  Hayashi Takanori、Hikichi Masahiro、Yukitake Jun、Harada Nobuhiro、Utsumi Toshiaki
- Journal Title
  
  Oncology Letters
  
  Volume: 14 Pages: 8060-8065
- DOI
  10.3892/ol.2017.7216
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K16172
[Presentation] 脂肪細胞はDPP4を分泌して卵巣がんのがん幹細胞性を促進する2021
- Author(s)
  田草川栞里、前田真男、矢野愛佳、西尾永司、林孝典、岡田誠治、鈴木元、浅井直也、藤井多久磨、佐谷秀行、下野洋平
- Organizer
  第80回　日本癌学会総会
- Data Source
  KAKENHI-PROJECT-19K09106
[Presentation] 脂肪細胞はMCP1を介して卵巣がんのがん幹細胞性を促進する2021
- Author(s)
  矢野愛佳、前田真男、西尾永司、田草川栞里、林孝典、鈴木元、浅井直也、藤井多久磨、佐谷秀行、下野洋平
- Organizer
  第80回　日本癌学会総会
- Data Source
  KAKENHI-PROJECT-19K09106
[Presentation] ニューロエストロゲンが摂食行動に及ぼす影響2019
- Author(s)
  林孝典，西尾永司，本田伸一郎，原田信広
- Organizer
  女性医学会
- Data Source
  KAKENHI-PROJECT-17K16172
[Presentation] ニューロエストロゲンが摂食行動に及ぼす影響とメカニズム2018
- Author(s)
  林孝典，本田伸一郎，原田信広
- Organizer
  ステロイドホルモン学会
- Data Source
  KAKENHI-PROJECT-17K16172
[Presentation] ニューロエストロゲンが食欲に及ぼす影響2018
- Author(s)
  林孝典，本田伸一郎，原田信広
- Organizer
  91回　日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-17K16172
[Presentation] 摂食関連因子にニューロエストロゲンが及ぼす影響2017
- Author(s)
  林孝典
- Organizer
  日本生化学会
- Data Source
  KAKENHI-PROJECT-17K16172

1. 下野洋平 (90594630)

# of Collaborated Projects: 6 results

# of Collaborated Products: 5 results
2. 本間尚子 (70321875)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. 西尾永司 (80367705)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. 熊本海生航 (10469322)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. 本田伸一郎 (40257639)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. Hikichi Masahiro (80794130)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. Maeda Masao (00769614)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
8. Satou Harunobu (50329736)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 喜島祐子 (60381175)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 内海俊明 (10176711)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. 三上哲夫 (90286352)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 深澤由里 (90392331)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 原田信広 (00189705)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 仁科隆史 (50598365)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 牛田かおり (50930872)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 柿崎真沙子 (20580872)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Hayashi Takanori 林 孝典

Research Projects

Research Products

Co-Researchers

ニューロエストロゲンの作用を基盤とした育児放棄の治療標的探索Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

糖質がもたらす情動変化にニューロエストロゲンがもたらす影響

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

大腸癌のエストロゲン応答多様性の背景にある分子機構の解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

大腸癌に対するエストロゲン作用の多様性についての包括的研究

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

遺伝子改変マウスを用いたニューロエストロゲンが摂食行動に与える影響

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Study of colorectal cancer suppression mechanism by estrogen using the new colorectal cancer animal model

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Neuroestrogens on neglect and investigating molecular mechanisms of action.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Overcoming Molecular Targeted Drug Resistance in Aromatase Inhibitor-Resistant Breast Cancer.

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

integrated analysis of mechanisms promoting tumorigenesis by adipocyte

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the function of neuroestrogen on feeding behavior.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Upregulation of CIP2A in estrogen depletion‐resistant breast cancer cells treated with low‐dose everolimus2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] miR-221 Targets QKI to Enhance the Tumorigenic Capacity of Human Colorectal Cancer Stem Cells.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Lack of association of ovariectomy-induced obesity with overeating and the reduction of physical activities.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A Hypoglycemia-inducing Giant Borderline Phyllodes Tumor Secreting High-molecular-weight Insulin-Like Growth Factor II: Immunohistochemistry and a Western Blot Analysis2018

Hayashi Takanori 林孝典