Jo Airi 城愛理 (渡辺愛理)

… Alternative Names

Jo-watanabe airi 城愛理

渡辺愛理

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Researcher Number	40726197
Other IDs
Affiliation (Current)	2026: 慶應義塾大学, 医学部(信濃町), 准教授 2026: 順天堂大学, 大学院医学研究科, 非常勤講師
Affiliation (based on the past Project Information) *help	2025: 慶應義塾大学, 医学部(信濃町), 准教授 2024: 順天堂大学, 医学(系)研究科(研究院), 准教授 2024: 順天堂大学, 大学院医学研究科, 准教授 2022 – 2023: 順天堂大学, 大学院医学研究科, 特任准教授 2021: 順天堂大学, 大学院医学研究科, 助教 2018 – 2020: 順天堂大学, 医学(系)研究科(研究院), 助教
Review Section/Research Field	Principal Investigator Basic Section 48040:Medical biochemistry-related Except Principal Investigator Medium-sized Section 48:Biomedical structure and function and related fields / Transformative Research Areas, Section (III)
Keywords	Principal Investigator 重炭酸イオン / 血管生理 / ペリサイト / 脳梗塞 / 虚血再灌流障害 / Gタンパク質共役型受容体 / 細胞内シグナル / 細胞内カルシウム / 受容体 / 細胞内シグナル伝達 / 重炭酸イオンシグナル / エキソサイトーシス … More Except Principal Investigator … More 脳梗塞 / 重炭酸イオン / Gタンパク質共役型受容体 / 構造解析 / 拮抗薬 / G-タンパク質共役型受容体 / 病態モデル / シグナル伝達 / 作働薬 / GPCR / 炎症性腸疾患 / 創傷治癒 / 生理活性脂質 Less

重炭酸イオンが生み出す新しいPericyte BiologyPrincipal Investigator
- Principal Investigator
  
  城愛理 (渡辺愛理 / 渡辺愛理)
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research)
- Review Section
  
  Basic Section 48040:Medical biochemistry-related
- Research Institution
  Keio University
  Juntendo University
pH signaling through bicarbonate-sensing GPCR
- Principal Investigator
  
  横溝岳彦
- Project Period (FY)
  2025 – 2029
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Juntendo University
Development of antagonists for G-protein coupled bicarbonate receptor
- Principal Investigator
  
  横溝岳彦
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Fund for the Promotion of Joint International Research (International Collaborative Research)
- Review Section
  
  Medium-sized Section 48:Biomedical structure and function and related fields
- Research Institution
  Juntendo University
虚血再灌流障害を引き起こす超急性期機序の解明－重炭酸イオンシグナルに着目して－Principal Investigator
- Principal Investigator
  
  城愛理 (渡辺愛理)
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48040:Medical biochemistry-related
- Research Institution
  Juntendo University
Bicarbonate-induced exocytosisPrincipal Investigator
- Principal Investigator
  
  Jo-Watanabe Airi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 48040:Medical biochemistry-related
- Research Institution
  Juntendo University
Development of BLT2 agonist based on the structure of BLT2
- Principal Investigator
  
  Yokomizo Takehiko
- Project Period (FY)
  2019 – 2024
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
- Review Section
  
  Medium-sized Section 48:Biomedical structure and function and related fields
- Research Institution
  Juntendo University
identification of bicarbonate receptorPrincipal Investigator
- Principal Investigator
  
  Jo-watanabe airi
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 48040:Medical biochemistry-related
- Research Institution
  Juntendo University

All 2025 2024 2023 2022 2021 2020 2019

All Journal Article Presentation

[Journal Article] Bicarbonate signalling via G protein-coupled receptor regulates ischaemia-reperfusion injury2024
- Author(s)
  Jo-Watanabe A, Inaba T, Osada T, Hashimoto R, Nishizawa T, Okuno T, Ihara S, Touhara K, Hattori N, Oh-Hora M, Nureki O, Yokomizo T
- Journal Title
  
  Nature Communications
  
  Volume: 15 Issue: 1 Pages: 1530-1530
- DOI
  10.1038/s41467-024-45579-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07255, KAKENHI-PROJECT-21H04798, KAKENHI-PROJECT-23K21384, KAKENHI-PROJECT-21H05037, KAKENHI-PROJECT-24H00601, KAKENHI-PROJECT-22K06888, KAKENHI-PROJECT-22K11711, KAKENHI-PROJECT-24KK0146
[Journal Article] Neutrophil trapping and nexocytosis, mast cell-mediated processes for inflammatory signal relay2024
- Author(s)
  Mihlan M., S. Wissmann, A. Gavrilov, L. Kaltenbach, M. Britz, K. Franke, B. Hummel, A. Imle, R. Suzuki, M. Stecher, K.M. Glaser, A. Lorentz, P. Carmeliet, T. Yokomizo, I. Hilgendorf, R. Sawarkar, A. Diz-Munoz, J.M. Buescher, G. Mittler, M. Maurer, K. Krause, M. Babina, L. Erpenbeck, M. Frank, et al.
- Journal Title
  
  Cell
  
  Volume: 187 Issue: 19 Pages: 5316-5335.e28
- DOI
  10.1016/j.cell.2024.07.014
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24H00601, KAKENHI-PROJECT-23K24028, KAKENHI-PROJECT-19KK0199, KAKENHI-PROJECT-24KK0146
[Journal Article] The leukotriene B4 /BLT1-dependent neutrophil accumulation exacerbates immune complex-mediated glomerulonephritis.2023
- Author(s)
  Shioda R, Jo-Watanabe A, Okuno T, Saeki K, Nakayama M, Suzuki Y, Yokomizo T
- Journal Title
  
  FASEB J
  
  Volume: 37 Issue: 2
- DOI
  10.1096/fj.202201936r
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06826, KAKENHI-PROJECT-21H04798, KAKENHI-PROJECT-22K06888, KAKENHI-PROJECT-19KK0199, KAKENHI-PROJECT-20K16148
[Journal Article] A Western Diet Alters Skin Ceramides and Compromises the Skin Barrier in Ears2022
- Author(s)
  Tan Kahbing Jasmine、Nakamizo Satoshi、Lee-Okada Hyeon-Cheol、Sato Reiko、Chow Zachary、Nakajima Saeko、Common John E.A.、Saeki Kazuko、Yokomizo Takehiko、Ginhoux Florent、Kabashima Kenji
- Journal Title
  
  Journal of Investigative Dermatology
  
  Volume: - Issue: 7 Pages: 2020-2023.e2
- DOI
  10.1016/j.jid.2021.12.017
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06923, KAKENHI-PROJECT-21K06826, KAKENHI-PROJECT-21H04798, KAKENHI-PROJECT-20H05697, KAKENHI-PROJECT-19KK0199
[Journal Article] Inhibition of both cyclooxygenase-1 and -2 promotes epicutaneous Th2 and Th17 sensitization and allergic airway inflammation on subsequent airway exposure to protease allergen in mice2021
- Author(s)
  Suchiva, P., Takai, T., Kamijo, S., Maruyama, N., Yokomizo, T., Sugimoto, Y., Okumura, K., Ikeda, S., Ogawa, H.
- Journal Title
  
  International Archives of Allergy and Immunology
  
  Volume: - Issue: 9 Pages: 788-799
- DOI
  10.1159/000514975
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22503, KAKENHI-PROJECT-17H03990, KAKENHI-PROJECT-18K08417, KAKENHI-PROJECT-21H04798, KAKENHI-PROJECT-21H02633, KAKENHI-PROJECT-19KK0199
[Journal Article] Dietary intake of n-3 polyunsaturated fatty acids alters the lipid mediator profile of the kidney but does not attenuate renal insufficiency.2021
- Author(s)
  Shioda R., Jo-Watanabe A., Lee-Okada H.C., Yasukawa K., Okuno T., Suzuki Y., Yokomizo T.
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 582 Pages: 49-56
- DOI
  10.1016/j.bbrc.2021.10.028
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07357, KAKENHI-PROJECT-21H04798, KAKENHI-PROJECT-19KK0199
[Journal Article] Leukotriene A4 hydrolase deficiency protects mice from diet-induced obesity by increasing energy expenditure through neuroendocrine axis.2020
- Author(s)
  Uzawa H, Kohno D, Koga T, Sasaki T, Fukunaka A, Okuno T, Jo-Watanabe A, Kazuno S, Miyatsuka T, Kitamura T, Fujitani Y, Watada H, Saeki K*, Yokomizo T
- Journal Title
  
  FASEB J
  
  Volume: 34(10) Issue: 10 Pages: 13949-13958
- DOI
  10.1096/fj.202001148r
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06923, KAKENHI-PROJECT-19K07357, KAKENHI-PROJECT-19K08971, KAKENHI-PROJECT-20K07328, KAKENHI-PROJECT-19KK0199, KAKENHI-PROJECT-18H02627, KAKENHI-PROJECT-20H03463
[Journal Article] Cyclooxygenase inhibition in mice heightens adaptive‐ and innate‐type responses against inhaled protease allergen and IL ‐332019
- Author(s)
  Maruyama Natsuko、Takai Toshiro、Kamijo Seiji、Suchiva Punyada、Ohba Mai、Takeshige Tomohito、Suzuki Mayu、Hara Mutsuko、Matsuno Kei、Harada Sonoko、Harada Norihiro、Nakae Susumu、Sudo Katsuko、Okuno Toshiaki、Yokomizo Takehiko、Ogawa Hideoki、Okumura Ko、Ikeda Shigaku
- Journal Title
  
  Allergy
  
  Volume: 印刷中 Issue: 11 Pages: 2237-2240
- DOI
  10.1111/all.13831
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09554, KAKENHI-PROJECT-16K09587, KAKENHI-PROJECT-17K10007, KAKENHI-PROJECT-18K08417, KAKENHI-PROJECT-19K07357, KAKENHI-PROJECT-19KK0199, KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05904, KAKENHI-PROJECT-18H02627, KAKENHI-PROJECT-18H02847, KAKENHI-PROJECT-16K08596
[Journal Article] BLT1 Mediates Commensal Bacteria-Dependent Innate Immune Signals to Enhance Antigen-Specific Intestinal IgA Responses2019
- Author(s)
  Nagatake T, Hirata SI, Koga T, Kuroda E, Kobari S, Suzuki H, Hosomi K, Matsumoto N, Yanrismet Y, Shimojou M, Morimoto S, Sasaki F, Ishii KJ, Yokomizo T, Kunisawa J.
- Journal Title
  
  Mucosal Immunol .
  
  Volume: 12 Issue: 5 Pages: 1082-1082
- DOI
  10.1038/s41385-019-0175-z
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K17997, KAKENHI-PROJECT-19KK0199, KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05904, KAKENHI-PROJECT-18H02627, KAKENHI-PROJECT-18H02674
[Presentation] A newfound bicarbonate-sensing G protein-coupled receptor regulates ,icrocirculation and ischemia-reperfusion injury.2025
- Author(s)
  Jo, Airi, Yokomizo, T
- Organizer
  Gordon Research Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24KK0146
[Presentation] A newfound bicarbonate-sensing G protein-coupled receptor regulates microcirculation and ischemia-reperfusion injury.2025
- Author(s)
  Jo, Airi Yokomizo, T
- Organizer
  Gordon Research Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19KK0199
[Presentation] FADS1/2二重ヘテロ欠損マウスによるNAFLDリスクアレルを模倣するモデルの解析2024
- Author(s)
  薛城軒, 李賢哲, 安藤美沙, 横溝岳彦.
- Organizer
  第97回日本生化学会
- Data Source
  KAKENHI-PROJECT-19KK0199
[Presentation] 重炭酸イオンを感知するGタンパク質共役型受容体の発見と脳虚血再灌流障害への作用2024
- Author(s)
  城愛理, 横溝岳彦.
- Organizer
  第97回日本生化学会シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-19KK0199
[Presentation] 重炭酸イオンを感知するGタンパク質共役型受容体の発見と脳虚血再灌流障害への作用2024
- Author(s)
  城（渡辺）愛理, 横溝岳彦
- Organizer
  第97回日本生化学会シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-24KK0146
[Presentation] The leukotriene B4-BLT1 axis in neutrophils exacerbates crescentic glomerulonephritis.2024
- Author(s)
  Oh-hora, M Shioda, R Jo-Watanabe, A Okuno, T Saeki, K Nakayama, M Suzuki, Y Yokomizo,T
- Organizer
  第51回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-19KK0199
[Presentation] 肝臓特異的FADS1/2二重欠損マウスの作製と表現型解析2024
- Author(s)
  薛城軒李賢哲安藤美沙横溝岳彦
- Organizer
  第66回日本脂質生化学会
- Data Source
  KAKENHI-PROJECT-19KK0199
[Presentation] Cellular senescence affects secretary phenotype and myogenic differentiation in mouse myoblasts2022
- Author(s)
  Ono T, Jo-Watanabe A , Yokomizo T
- Organizer
  第45回日本基礎老化学会大会
- Data Source
  KAKENHI-PROJECT-19KK0199
[Presentation] Identification of the pathological mechanism of glomerulonephritis by the LTB4-BLT1 axis and its application to therapy2022
- Author(s)
  Shioda R, Jo-Watanabe A, Okuno T, Nakayama M, Yokomizo T , Suzuki Y
- Organizer
  World Congress of Nephrology (WCN) WCN’22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19KK0199
[Presentation] The leukotriene B4-BLT1 axis in neutrophils exacerbates crescentic glomerulonephritis.2022
- Author(s)
  Oh-hora M, Shioda R, Jo-Watanabe A, Okuno T, Saeki K, Nakayama M, Suzuki Y, YokomizoT.
- Organizer
  第51回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-20K16148
[Presentation] The leukotriene B4-BLT1 axis in neutrophils exacerbates crescentic glomerulonephritis.2022
- Author(s)
  Oh-hora M, Shioda R, Jo-Watanabe A, Okuno T, Saeki K, Nakayama M, Suzuki Y , Yokomizo T
- Organizer
  第51回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-19KK0199
[Presentation] The leukotriene B4/BLT1-dependent neutrophil accumulation exacerbates immune complex-mediated glomerulonephritis2022
- Author(s)
  Yokomizo T, Shioda R, Okuno T, Nakayama M, Suzuki Y , Jo-Watanabe A
- Organizer
  62th ICBL, International Conference on the Bioscience of Lipids, Invited lecture
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19KK0199
[Presentation] Leukotriene B4-BLT1-dependent neutrophil recruitment contributes to the pathogenesis of crescent glomerulonephritis.2022
- Author(s)
  Shioda R, Jo-Watanabe A, Okuno T, Yokomizo T , Suzuki Y
- Organizer
  第11回CKD frontier
- Data Source
  KAKENHI-PROJECT-19KK0199
[Presentation] ロイコトリエンB4-BLT1軸はFcγ受容体依存的に腎炎急性期の好中球浸潤を制御する2021
- Author(s)
  塩田遼太郎, 城愛理, 奥野利明, 鈴木祐介, 横溝岳彦
- Organizer
  第63回日本脂質生化学会
- Data Source
  KAKENHI-PROJECT-19KK0199
[Presentation] ロイコトリエンB4-BLT1軸はFcγ受容体依存的に腎炎急性期の好中球浸潤を制御する2021
- Author(s)
  塩田遼太郎, 城愛理, 横溝岳彦, 鈴木祐介
- Organizer
  第64回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-19KK0199
[Presentation] Leukotriene B4-BLT1 axis controls neutrophil accumulation via Fcγ receptor-dependent leukotriene B4 production in experimental glomerulonephritis2021
- Author(s)
  Shioda R, Jo-Watanabe A, Okuno T, Nakayama M, Yokomizo T, Suzuki Y
- Organizer
  American Society of Nephrology(ASN) Kidney Week 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19KK0199
[Presentation] LTB4-BLT1軸による糸球体腎炎の病態制御機構の解明と治療への応用2021
- Author(s)
  塩田遼太郎, 城愛理, 奥野利明, 鈴木祐介, 横溝岳彦
- Organizer
  第94回日本生化学会
- Data Source
  KAKENHI-PROJECT-19KK0199
[Presentation] ロイコトリエンB4-BLT1軸は抗糸球体基底膜腎炎モデルの病態促進に寄与する2020
- Author(s)
  塩田遼太郎城愛理横溝岳彦鈴木祐介
- Organizer
  第62回日本脂質生化学会
- Data Source
  KAKENHI-PROJECT-19KK0199
[Presentation] BLT1 promotes intestinal IgA production against oral vaccine by mediating commensal bacteria-dependent innate immune signals for plasma cell proliferation2019
- Author(s)
  Nagatake, T Hirata, S I Koga, T Kuroda, E Kobari, S Suzuki, H Hosomi, K Matsumoto, N Yanrismet, Y Shimojou, M Marimoto, S Sasaki, F Ishii, K J Yokomizo, T Kunisawa, J
- Organizer
  60th ICBL, International Conference on the Bioscience of Lipids, Invited lecture
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19KK0199

1. Yokomizo Takehiko (60302840)

# of Collaborated Projects: 3 results

# of Collaborated Products: 19 results
2. 稲葉俊東 (30879672)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. HARADA Norihiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. TAKESHIGE tomohito

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. HARADA sonoko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. MATSUNO kei

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 佐伯和子

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
8. 長田貴宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 杉本幸彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 奥野利明

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 伊藤潤

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 細見晃司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Jo Airi 城 愛理 (渡辺 愛理)

Jo-watanabe airi 城 愛理

渡辺愛理

渡辺 愛理

Research Projects

Research Products

Co-Researchers

重炭酸イオンが生み出す新しいPericyte BiologyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

pH signaling through bicarbonate-sensing GPCR

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of antagonists for G-protein coupled bicarbonate receptor

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

虚血再灌流障害を引き起こす超急性期機序の解明－重炭酸イオンシグナルに着目して－Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Bicarbonate-induced exocytosisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of BLT2 agonist based on the structure of BLT2

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

identification of bicarbonate receptorPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Bicarbonate signalling via G protein-coupled receptor regulates ischaemia-reperfusion injury2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Neutrophil trapping and nexocytosis, mast cell-mediated processes for inflammatory signal relay2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The leukotriene B4 /BLT1-dependent neutrophil accumulation exacerbates immune complex-mediated glomerulonephritis.2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A Western Diet Alters Skin Ceramides and Compromises the Skin Barrier in Ears2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Inhibition of both cyclooxygenase-1 and -2 promotes epicutaneous Th2 and Th17 sensitization and allergic airway inflammation on subsequent airway exposure to protease allergen in mice2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Dietary intake of n-3 polyunsaturated fatty acids alters the lipid mediator profile of the kidney but does not attenuate renal insufficiency.2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Leukotriene A4 hydrolase deficiency protects mice from diet-induced obesity by increasing energy expenditure through neuroendocrine axis.2020

Jo Airi 城愛理 (渡辺愛理)

Jo-watanabe airi 城愛理

渡辺愛理