Katsuda Takeshi 勝田毅

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KATSUDA Takeshi 勝田毅

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Researcher Number	40732326
Other IDs
Affiliation (Current)	2026: 東京大学, 大学院工学系研究科(工学部), 助教
Affiliation (based on the past Project Information) *help	2025: 東京大学, 工学(系)研究科(研究院), 助教 2024 – 2025: 東京大学, 大学院工学系研究科(工学部), 助教 2016 – 2017: 国立研究開発法人国立がん研究センター, 研究所, 研究員
Review Section/Research Field	Principal Investigator Basic Section 45010:Genetics-related / 0701:Biology at molecular to cellular levels, and related fields / Medium-sized Section 43:Biology at molecular to cellular levels, and related fields / Sections That Are Subject to Joint Review: Basic Section45010:Genetics-related ,Basic Section45020:Evolutionary biology-related / Basic Section 45020:Evolutionary biology-related / Chemical biology Except Principal Investigator Basic Section 90110:Biomedical engineering-related
Keywords	Principal Investigator 肝細胞 / CRISPRスクリーニング / CLiP / ヒト肝細胞 / 肝細胞移植 / 移植 / 増殖誘導 / in vitro増殖 / 多極性有糸分裂 / 細胞老化 … More / 倍数性減少 / 移植シミュレータ / 空間トランスクリプトーム / 再生医療 / 化合物ライブラリ / 高置換 / シトクロームP450 / 低分子化合物 / リプログラミング / 肝前駆細胞 … More Except Principal Investigator hiPSCS / Liver / CRISPR technology / organ on chip Less

細胞競合に着目した肝細胞移植シミュレータの開発Principal Investigator
- Principal Investigator
  
  勝田毅
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 45010:Genetics-related
  Basic Section 45020:Evolutionary biology-related
  Sections That Are Subject to Joint Review: Basic Section45010:Genetics-related ,Basic Section45020:Evolutionary biology-related
- Research Institution
  The University of Tokyo
肝疾患の新規標的を解明するためのhiPSC-MPS-CRISPR統合スクリーニング
- Principal Investigator
  
  LECLERC Eric
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 90110:Biomedical engineering-related
- Research Institution
  The University of Tokyo
倍数性減少を標的とした肝細胞若返りの試みPrincipal Investigator
- Principal Investigator
  
  勝田毅
- Project Period (FY)
  2025 – 2026
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 43:Biology at molecular to cellular levels, and related fields
- Research Institution
  The University of Tokyo
肝細胞移植シミュレータの包括化に向けた空間エピゲノムと高解像度臓器イメージングPrincipal Investigator
- Principal Investigator
  
  勝田毅
- Project Period (FY)
  2025
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research)
- Review Section
  
  Basic Section 45010:Genetics-related
- Research Institution
  The University of Tokyo
成人肝細胞のin vitro増殖メカニズムの解明Principal Investigator
- Principal Investigator
  
  勝田毅
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0701:Biology at molecular to cellular levels, and related fields
- Research Institution
  The University of Tokyo
Generation of hepatic progenitor cells from human hepatocytes using small moleculesPrincipal Investigator
- Principal Investigator
  
  KATSUDA Takeshi
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Chemical biology
- Research Institution
  National Cancer Center Japan

All 2025 2024 2018 2017 2016

All Journal Article Presentation Patent

[Journal Article] In vivo CRISPR screening reveals epigenetic regulators of hepatobiliary plasticity2025
- Author(s)
  Sussman JH, Cure HW, Yuan S, Ito K, Asangani IA, Garcia BA, Stanger BZ, Katsuda T.
- Journal Title
  
  Genes & Development
  
  Volume: 39 Issue: 9-10 Pages: 603-616
- DOI
  10.1101/gad.352420.124
- Data Source
  KAKENHI-PROJECT-24K23176
[Journal Article] The yin and yang of pioneer transcription factors: Dual roles in repression and activation2024
- Author(s)
  Katsuda T, Sussman JH, Zaret KS, Stanger BZ.
- Journal Title
  
  BioEssays
  
  Volume: 46 Issue: 10
- DOI
  10.1002/bies.202400138
- Data Source
  KAKENHI-PROJECT-24K23176
[Journal Article] Mutant IDH1 inhibition induces dsDNA sensing to activate tumor immunity2024
- Author(s)
  Wu MJ, Kondo H, Kammula AV, Shi L, Xiao Y, Dhiab S, Xu Q, Slater CJ, Avila OI, Merritt J, Kato H, Kattel P, Sussman J, Gritti I, Eccleston J, Sun Y, Cho HM, Olander K, Katsuda T et al.
- Journal Title
  
  Science
  
  Volume: 385 Issue: 6705
- DOI
  10.1126/science.adl6173
- Data Source
  KAKENHI-PROJECT-24K23176
[Journal Article] Multiplexed Imaging Mass Cytometry Analysis Characterizes the Vascular Niche in Pancreatic Cancer2024
- Author(s)
  Sussman JH, Kim N, Kemp SB, Traum D, Katsuda T, Kahn BM, Xu J, Kim IK, Eskandarian C, Delman D, Beatty GL, Kaestner KH, Simpson AL, Stanger BZ.
- Journal Title
  
  Cancer Research
  
  Volume: 84 Issue: 14 Pages: 2364-2376
- DOI
  10.1158/0008-5472.can-23-2352
- Data Source
  KAKENHI-PROJECT-24K23176
[Journal Article] Generation of Chemically Induced Liver Progenitors (CLiPs) from Rat Adult Hepatocytes2018
- Author(s)
  Katsuda Takeshi、Hosaka Kazunori、Ochiya Takahiro
- Journal Title
  
  BIO-PROTOCOL
  
  Volume: 7 Issue: 2 Pages: 1-26
- DOI
  10.21769/bioprotoc.2689
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K16643
[Journal Article] 成熟肝細胞からの，高い再生能を有しかつ培養可能な肝前駆細胞へのリプログラミング2018
- Author(s)
  勝田毅、落谷孝広
- Journal Title
  
  再生医療
  
  Volume: 17 Pages: 78-84
- Data Source
  KAKENHI-PROJECT-16K16643
[Journal Article] Chemically induced liver progenitors (CLiPs): a novel cell source for hepatocytes and biliary epithelial cells2017
- Author(s)
  Takeshi Katsuda, Takahiro Ochiya
- Journal Title
  
  Methods in Molecular Biology
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K16643
[Journal Article] 低分子化合物による成熟肝細胞から肝前駆細胞へのin vitroリプログラミング (特集再生医療の新規知見と発展)2017
- Author(s)
  勝田毅、落谷孝広
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: 68 Pages: 363-368
- NAID
  40021346807
- Data Source
  KAKENHI-PROJECT-16K16643
[Journal Article] Exploration for Cell Sources for Liver Regenerative Medicine: “CLiP” as a Dawn of Cell Transplantation Therapy2017
- Author(s)
  Kazunori Hosaka, Takeshi Katsuda, Shuji Terai, Takahiro Ochiya
- Journal Title
  
  Stem Cells and Cancer in Hepatology
  
  Volume: 印刷中
- Data Source
  KAKENHI-PROJECT-16K16643
[Journal Article] Generation of hepatic organoids with biliary structures2017
- Author(s)
  Takeshi Katsuda, Takahiro Ochiya, Yasuyuki Sakai
- Journal Title
  
  Methods in Molecular Biology
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K16643
[Journal Article] Biological and clinical insights offered by chemically induced liver progenitors (CLiPs)2017
- Author(s)
  Katsuda Takeshi、Ochiya Takahiro
- Journal Title
  
  Stem Cell Investigation
  
  Volume: 4 Pages: 68-68
- DOI
  10.21037/sci.2017.08.04
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K16643
[Journal Article] Conversion of Terminally Committed Hepatocytes to Culturable Bipotent Progenitor Cells with Regenerative Capacity2017
- Author(s)
  Katsuda T, Kawamata M, Hagiwara K, Takahashi RU, Yamamoto Y, Camargo FD, Ochiya T
- Journal Title
  
  Cell Stem Cell
  
  Volume: 20 Issue: 1 Pages: 41-55
- DOI
  10.1016/j.stem.2016.10.007
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K16643
[Patent] ヒト肝前駆細胞の調製方法2017
- Inventor(s)
  山田哲正、落谷孝広、勝田毅
- Industrial Property Rights Holder
  山田哲正、落谷孝広、勝田毅
- Industrial Property Rights Type
  特許
- Filing Date
  2017
- Data Source
  KAKENHI-PROJECT-16K16643
[Patent] ヒト肝前駆細胞の調製方法2016
- Inventor(s)
  落谷孝広、勝田毅
- Industrial Property Rights Holder
  落谷孝広、勝田毅
- Industrial Property Rights Type
  特許
- Filing Date
  2016-10-28
- Data Source
  KAKENHI-PROJECT-16K16643
[Presentation] Chemically induced liver progenitors as a novel cell source for liver regenerative medicine2024
- Author(s)
  Takeshi Katsuda
- Organizer
  BDMC2024
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24K23176
[Presentation] パイオニアファクターSOX4による肝細胞の胆管リプログラミング開始機構2024
- Author(s)
  勝田毅，Jonathan H. Sussman, 伊藤謙治, Andrew Katznelson, Salina Yuan, 竹中なおみ，Jinyang Li, Merrell J Allyson, Hector Cure, Qinglan Li, Reyaz Ur Rasool, Irfan A. Asangani, Kenneth S Zaret, Ben Z Stanger
- Organizer
  第31回肝細胞研究会
- Data Source
  KAKENHI-PROJECT-24K23176
[Presentation] 低分子化合物による成熟肝細胞から肝前駆細胞へのin vitroリプログラミング2017
- Author(s)
  勝田　毅
- Organizer
  第16回日本再生医療学会（ランチョンセミナー）
- Place of Presentation
  仙台国際センター
- Invited
- Data Source
  KAKENHI-PROJECT-16K16643
[Presentation] 成熟肝細胞からの肝前駆細胞誘導とその再生医療への応用可能性2017
- Author(s)
  勝田毅、川又理樹、萩原啓太郎、高橋陵宇、山本雄介、保坂和徳、落谷孝広
- Organizer
  第136 回日本薬理学会関東部会
- Invited
- Data Source
  KAKENHI-PROJECT-16K16643
[Presentation] In vitro reprogramming of mature hepatocytes to culturable liver progenitor cells using small molecules2017
- Author(s)
  Takeshi Katsuda, Masaki Kawamata, Keitaro Hagiwara, Ryou-u Takahashi, Yusuke Yamamoto, Kazunori Hosaka, Takahiro Ochiya
- Organizer
  第15回幹細胞シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-16K16643

1. OCHIYA Takahiro (60192530)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
2. MATSUZAKI Juntaro (60464864)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. SAITO Yoshimasa (90360114)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. TAKEUCHI Atsuko (80154970)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 大西雅也 (11012328)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 西川昌輝 (40843149)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. LECLERC Eric (30759436)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 酒井康行 (00235128)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 山田泰弘

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 山口智子

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 保坂和徳

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results

Katsuda Takeshi 勝田 毅

KATSUDA Takeshi 勝田 毅

Research Projects

Research Products

Co-Researchers

細胞競合に着目した肝細胞移植シミュレータの開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

肝疾患の新規標的を解明するためのhiPSC-MPS-CRISPR統合スクリーニング

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

倍数性減少を標的とした肝細胞若返りの試みPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

肝細胞移植シミュレータの包括化に向けた空間エピゲノムと高解像度臓器イメージングPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

成人肝細胞のin vitro増殖メカニズムの解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Generation of hepatic progenitor cells from human hepatocytes using small moleculesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] In vivo CRISPR screening reveals epigenetic regulators of hepatobiliary plasticity2025

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The yin and yang of pioneer transcription factors: Dual roles in repression and activation2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Mutant IDH1 inhibition induces dsDNA sensing to activate tumor immunity2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Multiplexed Imaging Mass Cytometry Analysis Characterizes the Vascular Niche in Pancreatic Cancer2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Generation of Chemically Induced Liver Progenitors (CLiPs) from Rat Adult Hepatocytes2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 成熟肝細胞からの，高い再生能を有しかつ培養可能な肝前駆細胞へのリプログラミング2018

Author(s)

Journal Title

Data Source

[Journal Article] Chemically induced liver progenitors (CLiPs): a novel cell source for hepatocytes and biliary epithelial cells2017

Author(s)

Journal Title

Data Source

[Journal Article] 低分子化合物による成熟肝細胞から肝前駆細胞へのin vitroリプログラミング (特集 再生医療の新規知見と発展)2017

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Exploration for Cell Sources for Liver Regenerative Medicine: “CLiP” as a Dawn of Cell Transplantation Therapy2017

Katsuda Takeshi 勝田毅

KATSUDA Takeshi 勝田毅

[Journal Article] 低分子化合物による成熟肝細胞から肝前駆細胞へのin vitroリプログラミング (特集再生医療の新規知見と発展)2017