KAKIMOTO YU 垣本由布

… Alternative Names

KAKIMOTO Yu 垣本由布

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Researcher Number	40734166
Other IDs	https://orcid.org/0000-0002-6952-6292
Affiliation (Current)	2025: 東海大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2024: 東海大学, 医学部, 教授 2020 – 2023: 東海大学, 医学部, 准教授 2017 – 2019: 東海大学, 医学部, 講師 2014 – 2016: 東海大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 58040:Forensics medicine-related / Legal medicine
Keywords	Principal Investigator 心肥大 / 心臓性突然死 / タンパク質 / 質量分析 / 異方性 / 突然死 / マイクロRNA / miRNA / CTNNA3 / MYH1 … More / プロテオーム / 心筋リモデリング / リン酸化 / イオンチャネル / カルシウム / Tubulin / 微小管 / 死後変化 / ウエスタンブロッティング / 心臓組織 / プロテオミクス / 虚血性心不全 / 高血圧性心不全 / MYH7 / プロテオーム解析 / 心臓 / 加齢 / 年齢推定 / カテプシン / リポフスチン / リソソーム / オートファジー / 生体分子 / 病理学 / 循環器・高血圧 / ヒト心臓組織 / シーケンシング / miR-221 / miRNA シーケンス / ホルマリン固定組織 / 次世代シーケンサー / 解剖組織検体 / 急性心筋梗塞 / miR-208 / ミオシン重鎖 / 心筋梗塞 / 解剖検体 / ヒト組織 / 心室 / 心房 Less

Anisotropic proteomic profiling in sudden cardiac deathPrincipal Investigator
- Principal Investigator
  
  垣本由布
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 58040:Forensics medicine-related
- Research Institution
  Tokai University
T-tubule remodeling and calcium handling dysfunction in fatal cardiac hypertrophyPrincipal Investigator
- Principal Investigator
  
  Kakimoto Yu
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 58040:Forensics medicine-related
- Research Institution
  Tokai University
A diagnostic approach for lethal cardiac hypertrophy based on the analysis of autophagy-lysosomal pathwayPrincipal Investigator
- Principal Investigator
  
  KAKIMOTO Yu
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 58040:Forensics medicine-related
- Research Institution
  Tokai University
Localization analysis of microRNAs relating to sudden cardiac death in conduction system of the human heartPrincipal Investigator
- Principal Investigator
  
  KAKIMOTO Yu
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Legal medicine
- Research Institution
  Tokai University
Comprehensive analysis of microRNAs using patients' tissues with acute myocardial infarction.Principal Investigator
- Principal Investigator
  
  KAKIMOTO Yu
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Legal medicine
- Research Institution
  Tokai University

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 Other

All Journal Article Presentation

[Journal Article] Proteomic profiling of sudden cardiac death with acquired cardiac hypertrophy2023
- Author(s)
  Kakimoto Yu、Ueda Atsushi、Ito Masatoshi、Tanaka Masayuki、Kubota Tomoko、Isozaki Shotaro、Osawa Motoki
- Journal Title
  
  International Journal of Legal Medicine
  
  Volume: 137 Issue: 5 Pages: 1453-1461
- DOI
  10.1007/s00414-023-03038-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K17411, KAKENHI-PROJECT-20K10565
[Journal Article] Cutoff value for hypertrophic heart weight in the Japanese population.2021
- Author(s)
  Kakimoto Y, Asakura K, Osawa M
- Journal Title
  
  Leg Med (Tokyo).
  
  Volume: 48 Pages: 101831-101831
- DOI
  10.1016/j.legalmed.2020.101831
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K10565
[Journal Article] Myocardial cathepsin D is downregulated in sudden cardiac death.2020
- Author(s)
  Kakimoto Y, Sasaki A, Niioka M, Kawabe N, Osawa M.
- Journal Title
  
  PLoS One
  
  Volume: 15(3) Issue: 3 Pages: e0230375-e0230375
- DOI
  10.1371/journal.pone.0230375
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K17419
[Journal Article] Myocardial lipofuscin accumulation in ageing and sudden cardiac death2019
- Author(s)
  Article | OPEN | Published: 01 March 2019 Myocardial lipofuscin accumulation in ageing and sudden cardiac death Yu Kakimoto, Chisa Okada, Noboru Kawabe, Ayumi Sasaki, Hideo Tsukamoto, Ryoko Nagao, Motoki Osawa
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 3304-3304
- DOI
  10.1038/s41598-019-40250-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K17419, KAKENHI-PROJECT-19H00299
[Journal Article] Overexpression of miR-221 in sudden death with cardiac hypertrophy patients2018
- Author(s)
  Yu Kakimoto, Masayuki Tanaka, Hideki Hayashi, Keiko Yokoyama, Motoki Osawa
- Journal Title
  
  Heliyon
  
  Volume: 4 Issue: 6 Pages: e00639-e00639
- DOI
  10.1016/j.heliyon.2018.e00639
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K17419
[Journal Article] MicroRNA Stability in FFPE Tissue Samples: Dependence on GC Content2016
- Author(s)
  Yu Kakimoto, Masayuki Tanaka, Hiroshi Kamiguchi, Eriko Ochiai, Motoki Osawa
- Journal Title
  
  PLoS ONE
  
  Volume: 11(9) Issue: 9 Pages: e0163125-e0163125
- DOI
  10.1371/journal.pone.0163125
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16K19300
[Journal Article] MicroRNA deep sequencing reveals chamber-specific miR-208 family expression patterns in the human heart2016
- Author(s)
  Kakimoto Y, Tanaka M, Kamiguchi H, Hayashi H, Ochiai E, Osawa M
- Journal Title
  
  International Journal of Cardiology
  
  Volume: 211 Pages: 43-48
- DOI
  10.1016/j.ijcard.2016.02.145
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26893278
[Journal Article] MicroRNA Stability in Postmortem FFPE Tissues: Quantitative Analysis Using Autoptic Samples from Acute Myocardial Infarction Patients.2015
- Author(s)
  Kakimoto Y, Kamiguchi H, Ochiai E, Satoh F, Osawa M
- Journal Title
  
  PLoS One
  
  Volume: 10(6) Issue: 6 Pages: e0129338-e0129338
- DOI
  10.1371/journal.pone.0129338
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08884, KAKENHI-PROJECT-26893278
[Presentation] 健常および肥大心における心筋三層のプロテオーム解析2023
- Author(s)
  垣本由布、上田篤、池田はるか、木村弥生、秋山知子、磯崎翔太郎、大澤資樹
- Organizer
  第113回日本病理学総会
- Data Source
  KAKENHI-PROJECT-23K27868
[Presentation] 中高年の心臓性突然死におけるサルコメアタンパク質の発現増加2023
- Author(s)
  垣本　由布、伊藤　誠敏,　上田　篤、磯崎　翔太郎、大澤　資樹
- Organizer
  第107次日本法医学会学術全国集会
- Data Source
  KAKENHI-PROJECT-20K10565
[Presentation] Proteomic approach to sudden cardiac death with acquired cardiac hypertrophy.2023
- Author(s)
  Y Kakimoto, A Ueda, M Ito, M Tanaka, T Kubota, S Isozaki, M Osawa.
- Organizer
  10th Biennial Meeting of the Association for European Cardiovascular Pathology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K27868
[Presentation] 中高年の心肥大と突然死2023
- Author(s)
  垣本由布
- Organizer
  第71回日本心臓病学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-23K27868
[Presentation] 心臓性突然死への法医学的アプローチ2022
- Author(s)
  垣本　由布
- Organizer
  第106次日本法医学会学術全国集会
- Invited
- Data Source
  KAKENHI-PROJECT-20K10565
[Presentation] 現代日本人における心肥大重量の検討2021
- Author(s)
  垣本由布、朝倉久美子、上田篤、大澤資樹
- Organizer
  第105次日本法医学会学術全国集会
- Data Source
  KAKENHI-PROJECT-20K10565
[Presentation] 現代日本人における心肥大とは何グラム以上か2021
- Author(s)
  垣本由布、朝倉久美子、大澤資樹
- Organizer
  第110回日本病理学総会
- Data Source
  KAKENHI-PROJECT-20K10565
[Presentation] 心不全パンデミック時代の突然死～法医学にできること～2020
- Author(s)
  垣本　由布
- Organizer
  第104次日本法医学会学術全国集会
- Invited
- Data Source
  KAKENHI-PROJECT-20K10565
[Presentation] 心筋リポフスチン沈着の法医診断的活用2019
- Author(s)
  垣本由布, 長尾　涼子, 落合　恵理子, 瀬戸　良久、大澤　資樹
- Organizer
  第103次日本法医学会学術全国集会
- Data Source
  KAKENHI-PROJECT-18K17419
[Presentation] 加齢に伴う心筋リポフスチン沈着とオートファジー機能2019
- Author(s)
  垣本由布、岡田千沙、河邉昇、長尾涼子、大澤資樹
- Organizer
  第108回日本病理学総会
- Data Source
  KAKENHI-PROJECT-18K17419
[Presentation] 生理的心肥大および病的心肥大におけるマクロRNAの発現プロファイリング2018
- Author(s)
  垣本由布、田中政之、林英樹、横山圭子、大澤資樹
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K17419
[Presentation] Overexpression of MiR-221 as an Indicator of Sudden Death with Cardiac Hypertrophy2018
- Author(s)
  Kakimoto Y, Kakiuchi Y, Ochiai E, Osawa M
- Organizer
  24th Congress of the International Academy of Legal Medicine
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K17419
[Presentation] microRNA を用いた法医解剖診断の可能性2017
- Author(s)
  垣本　由布
- Organizer
  第101次日本法医学会学術全国集会
- Invited
- Data Source
  KAKENHI-PROJECT-16K19300
[Presentation] 剖検組織検体を用いたmicroRNA Deep Sequencingの検討2016
- Author(s)
  垣本由布、佐藤文子、落合恵理子、大澤資樹
- Organizer
  第100次日本法医学会学術全国集会
- Place of Presentation
  東京都品川区きゅりあん
- Year and Date
  2016-06-15
- Data Source
  KAKENHI-PROJECT-26893278
[Presentation] マイクロＲＮＡを用いた死後診断の展望：死後経過時間とホルマリン固定期間の影響2015
- Author(s)
  垣本由布, 佐藤文子, 宮下京子, 大澤資樹
- Organizer
  第99次日本法医学会学術全国集会
- Place of Presentation
  高知市文化プラザかるぽーと
- Year and Date
  2015-06-10
- Data Source
  KAKENHI-PROJECT-26893278
[Presentation] Detection of miRNAs in tissue samples at autopsy: A trial for diagnostics at postmortem2015
- Author(s)
  Y. Kakimoto, H. Kamiguchi, E. Ochiai, F. Satoh and M. Osawa
- Organizer
  26th Congress of the International Society for Forensic Genetics
- Place of Presentation
  Auditorium Maximum of the Jagiellonian University、Krakow、Porland
- Year and Date
  2015-08-31
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26893278
[Presentation] マイクロＲＮＡを用いた死後診断の展望：　死後経過時間とホルマリン固定期間の影響
- Author(s)
  垣本由布、佐藤文子、宮下京子、大澤資樹
- Organizer
  第99次日本法医学会学術全国集会
- Place of Presentation
  高知市文化プラザかるぽーと
- Year and Date
  2015-06-10 – 2015-06-12
- Data Source
  KAKENHI-PROJECT-26893278

1. 磯崎翔太郎 (60834504)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
2. 上田篤 (90728560)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
3. KAMIGUCHI Hiroshi

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. TANAKA Masayuki

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. OCHIAI Eriko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 大澤資樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

KAKIMOTO YU 垣本 由布

KAKIMOTO Yu 垣本 由布

Research Projects

Research Products

Co-Researchers

Anisotropic proteomic profiling in sudden cardiac deathPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

T-tubule remodeling and calcium handling dysfunction in fatal cardiac hypertrophyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

A diagnostic approach for lethal cardiac hypertrophy based on the analysis of autophagy-lysosomal pathwayPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Localization analysis of microRNAs relating to sudden cardiac death in conduction system of the human heartPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Comprehensive analysis of microRNAs using patients' tissues with acute myocardial infarction.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Proteomic profiling of sudden cardiac death with acquired cardiac hypertrophy2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cutoff value for hypertrophic heart weight in the Japanese population.2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Myocardial cathepsin D is downregulated in sudden cardiac death.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Myocardial lipofuscin accumulation in ageing and sudden cardiac death2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Overexpression of miR-221 in sudden death with cardiac hypertrophy patients2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] MicroRNA Stability in FFPE Tissue Samples: Dependence on GC Content2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] MicroRNA deep sequencing reveals chamber-specific miR-208 family expression patterns in the human heart2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] MicroRNA Stability in Postmortem FFPE Tissues: Quantitative Analysis Using Autoptic Samples from Acute Myocardial Infarction Patients.2015

Author(s)

Journal Title

DOI

Data Source

[Presentation] 健常および肥大心における心筋三層のプロテオーム解析2023

Author(s)

Organizer

Data Source

[Presentation] 中高年の心臓性突然死におけるサルコメアタンパク質の発現増加2023

KAKIMOTO YU 垣本由布

KAKIMOTO Yu 垣本由布

[Presentation] マイクロＲＮＡを用いた死後診断の展望：　死後経過時間とホルマリン固定期間の影響