Shiraishi Taro 白石太郎

… Alternative Names

白石太郎シライシタロウ

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Researcher Number	40734603
Other IDs	https://orcid.org/0000-0002-6540-8029
Affiliation (Current)	2025: 京都大学, 理学研究科, 講師
Affiliation (based on the past Project Information) *help	2025: 東京大学, 大学院農学生命科学研究科(農学部), 助教 2022 – 2023: 東京大学, 大学院農学生命科学研究科(農学部), 助教 2020: 東京大学, 生物生産工学研究センター, 助教 2016 – 2018: 東京大学, 生物生産工学研究センター, 助教
Review Section/Research Field	Principal Investigator Basic Section 37020:Chemistry and chemical methodology of biomolecules-related / 0601:Agricultural chemistry and related fields Except Principal Investigator Basic Section 37010:Bio-related chemistry / Transformative Research Areas, Section (II) / Science and Engineering
Keywords	Principal Investigator 天然物化学 / 輸送体 / 化合物ライブラリー / 放線菌 / 核酸系化合物 Except Principal Investigator ホスホン酸 / ポリケチド / 反応機構 / 生合成 / 酵素 … More / 代謝 / タンパク質立体構造予測 / 生化学 / 機械学習 / テルペン / 生合成酵素 / 天然物化学 / 天然有機化合物 / 生体分子 / 結晶構造解析 / 生体触媒 / ポリケタイド / テルペノイド / 天然物 / 生合成遺伝子 / reaction mechanism / terpene / carbazole / nucleoside antibiotic / Biosynthesis / ヌクレオシド / 放線菌 / 生合成マシナリー / 電子環状反応 / 遺伝子 / 天然化合物 / 生物活性物質 Less

Development of a Next-Generation Enzyme-Substrate Complex Prediction Method Considering the Reaction Information and Predicted 3D Structure
- Principal Investigator
  
  森脇由隆
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 37010:Bio-related chemistry
- Research Institution
  Institute of Science Tokyo
天然物BGCにコードされた輸送体の解析手法の確立と機能解明Principal Investigator
- Principal Investigator
  
  白石太郎
- Project Period (FY)
  2025 – 2026
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 37020:Chemistry and chemical methodology of biomolecules-related
- Research Institution
  The University of Tokyo
天然物生合成機構の改変による革新的ペプチド－核酸融合化合物ライブラリーの構築Principal Investigator
- Principal Investigator
  
  白石太郎
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0601:Agricultural chemistry and related fields
- Research Institution
  The University of Tokyo
構造多様性一挙構築型生体反応の集積・予知・創出
- Principal Investigator
  
  葛山智久
- Project Period (FY)
  2022 – 2026
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (II)
- Research Institution
  The University of Tokyo
Development and precise functional analysis of innovative biosynthetic machinery to create complex skeletons
- Principal Investigator
  
  Kuzuyama Tomohisa
- Project Period (FY)
  2016 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  The University of Tokyo

All 2024 2023 2022 2021 2019 2018 2017 2016

All Journal Article Presentation

[Journal Article] Discovery of type II polyketide synthase-like enzymes for the biosynthesis of cispentacin2023
- Author(s)
  Hibi Genki、Shiraishi Taro、Umemura Tatsuki、Nemoto Kenji、Ogura Yusuke、Nishiyama Makoto、Kuzuyama Tomohisa
- Journal Title
  
  Nature Communications
  
  Volume: 14 Issue: 1 Pages: 8065-8065
- DOI
  10.1038/s41467-023-43731-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-22H05120
[Journal Article] Complete Biosynthetic Pathway of the Phosphonate Phosphonothrixin: Two Distinct Thiamine Diphosphate-Dependent Enzymes Divide the Work to Form a C-C Bond2022
- Author(s)
  Zhu Yuxun、Shiraishi Taro、Lin Jianwen、Inaba Keito、Ito Atsuro、Ogura Yusuke、Nishiyama Makoto、Kuzuyama Tomohisa
- Journal Title
  
  Journal of the American Chemical Society
  
  Volume: 144 Issue: 37 Pages: 16715-16719
- DOI
  10.1021/jacs.2c06546
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22H05120
[Journal Article] Biosynthetic pathways and enzymes involved in the production of phosphonic acid natural products2021
- Author(s)
  Shiraishi T, Kuzuyama T.
- Journal Title
  
  Biosci Biotechnol Biochem
  
  Volume: 85 Issue: 1 Pages: 42-52
- DOI
  10.1093/bbb/zbaa052
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-16H06453
[Journal Article] 新奇骨格を創成する革新的生合成マシナリーの開拓2019
- Author(s)
  白石太郎、葛山智久
- Journal Title
  
  Farumashia
  
  Volume: 55 Issue: 7 Pages: 679-683
- DOI
  10.14894/faruawpsj.55.7_679
- NAID
  130007671598
- ISSN
  0014-8601, 2189-7026
- Language
  Japanese
- Data Source
  KAKENHI-PLANNED-16H06453
[Journal Article] Recent advances in the biosynthesis of nucleoside antibiotics2019
- Author(s)
  Shiraishi T, Kuzuyama T.
- Journal Title
  
  J Antibiot
  
  Volume: 72 Issue: 12 Pages: 913-923
- DOI
  10.1038/s41429-019-0236-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-16H06453
[Journal Article] The Amipurimycin and Miharamycin Biosynthetic Gene Clusters: Unraveling the Origins of 2-Aminopurinyl Peptidyl Nucleoside Antibiotics2019
- Author(s)
  Romo AJ, Shiraishi T, Ikeuchi H, Lin GM, Geng Y, Lee YH, Liem PH, Ma T, Ogasawara Y, Shin-ya K, Nishiyama M, Kuzuyama T, Liu HW.
- Journal Title
  
  J Am Chem Soc
  
  Volume: 141 Issue: 36 Pages: 14152-14159
- DOI
  10.1021/jacs.9b03021
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06453
[Journal Article] Biosynthesis of the uridine-derived nucleoside antibiotic A-94964: Identification and characterization of the biosynthetic gene cluster provide insight into the biosynthetic pathway2019
- Author(s)
  Shiraishi, T., Nishiyama, M., Kuzuyama T.
- Journal Title
  
  Org. Biomol. Chem.
  
  Volume: 17 Issue: 3 Pages: 461-466
- DOI
  10.1039/c8ob02765j
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-16H06453
[Journal Article] Fosfomycin Biosynthesis via Transient Cytidylylation of 2-Hydroxyethylphosphonate by the Bifunctional Fom1 Enzyme2017
- Author(s)
  Su-Hee Cho, Seung-Young Kim, Takeo Tomita, Taro Shiraishi, Jin-Soo Park, Shusuke Sato, Fumitaka Kudo, Tadashi Eguchi, Nobutaka Funa, Makoto Nishiyama and Tomohisa Kuzuyama
- Journal Title
  
  ACS Chem. Biol.
  
  Volume: 12 Pages: 2209-2215
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-16H06453
[Presentation] 計算科学を用いた真菌由来テルペン環化酵素の反応機構解析2024
- Author(s)
  烏野裕作, 佐藤玄, 白石太郎, 葛山智久
- Organizer
  日本農芸化学会2024年度大会
- Data Source
  KAKENHI-PLANNED-22H05120
[Presentation] Studies on terpene synthases from cyanobacteria2024
- Author(s)
  Jiayi Yu, Taro Shiraishi, Ayako Yoshida, Tomohisa Kuzuyama
- Organizer
  日本農芸化学会2024年度大会
- Data Source
  KAKENHI-PLANNED-22H05120
[Presentation] カイトセファリンの生合成研究2024
- Author(s)
  前野優香理, 齋藤直也, 白石太郎, 小川哲弘, 丸山潤一, 新家一男 , 葛山智久
- Organizer
  日本農芸化学会2024年度大会
- Data Source
  KAKENHI-PLANNED-22H05120
[Presentation] Studies on the biosynthesis of phenazine derivatives from Streptomyces purpeofuscus and S. prunicolor2024
- Author(s)
  Dan Xia, Qi Luo, Taro Shiraishi, Kazuo Shin-ya, Tomohisa Kuzuyama
- Organizer
  日本農芸化学会2024年度大会
- Data Source
  KAKENHI-PLANNED-22H05120
[Presentation] Biosynthesis of the acyl side chain in the nucleoside antibiotic A-94964 by unusual Type I polyketide synthase of Streptomyces sp. SANK 604042023
- Author(s)
  Hao Xu, Taro Shiraishi, Tomohisa Kuzuyama
- Organizer
  日本農芸化学会2023年度大会
- Data Source
  KAKENHI-PLANNED-22H05120
[Presentation] 放線菌が生産する核酸系抗生物質の生合成遺伝子の同定とその機構解析2023
- Author(s)
  白石太郎
- Organizer
  第 37 回(2023 年度)日本放線菌学会
- Invited
- Data Source
  KAKENHI-PLANNED-22H05120
[Presentation] Biosynthesis of the non-proteinogenic amino acid cispentacin in actinomycetes2023
- Author(s)
  Genki Hibi, Taro Shiraishi, Tomohisa Kuzuyama
- Organizer
  4th International Conference on Natural Product Discovery and Development in the Genomic Era
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-22H05120
[Presentation] Discovery of an unprecedented use of thiamine diphosphate in natural product biosynthesis2023
- Author(s)
  Yuxun ZHU, Taro Shiraishi, Tomohisa Kuzuyama
- Organizer
  日本農芸化学会2023年度大会
- Data Source
  KAKENHI-PLANNED-22H05120
[Presentation] Biosynthesis of the nucleoside antibiotics angustmycins2023
- Author(s)
  Taro Shiraishi, Tomohisa Kuzuyama
- Organizer
  4th International Conference on Natural Product Discovery and Development in the Genomic Era
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-22H05120
[Presentation] Biosynthetic Study on the Nucleoside Antibiotic Amipurimycin2023
- Author(s)
  Taro Shiraishi, Genki Hibi, Tatsuki Umemura, Hideo Ikeuchi, Makoto Nishiyama, Tomohisa Kuzuyama
- Organizer
  2023 The 1st Taiwan-Japan Bilateral Symposium on Natural Products Biosynthesis
- Invited
- Data Source
  KAKENHI-PLANNED-22H05120
[Presentation] A C-C bond formation through the transfer of a Breslow intermediate between two distinct thiamine diphosphate-dependent enzymes2023
- Author(s)
  朱裕勛, 白石太郎, 伊藤篤朗, 小倉由資, 西山真, 葛山智久
- Organizer
  第65回天然有機化合物討論会
- Data Source
  KAKENHI-PLANNED-22H05120
[Presentation] Biosynthetic Study on the Nucleoside Antibiotic Amipurimycin2023
- Author(s)
  Taro Shiraishi, Genki Hibi, Tatsuki Umemura, Hideo Ikeuchi, Makoto Nishiyama and Tomohisa Kuzuyama
- Organizer
  2023 The 1st Taiwan-Japan Bilateral Symposium on Natural Products Biosynthesis
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K20567
[Presentation] Studies on Diterpene Synthases from Cyanobacteria2023
- Author(s)
  Jiayi Yu, Taro Shiraishi, Tomohisa Kuzuyama
- Organizer
  第33回イソプレノイド研究会
- Data Source
  KAKENHI-PLANNED-22H05120
[Presentation] 放線菌が生産する核酸系抗生物質の生合成遺伝子の同定とその機構解析2023
- Author(s)
  白石太郎
- Organizer
  2023年度（第37回）日本放線菌学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-22K20567
[Presentation] 特殊アミノ酸シスペンタシン生合成の再構成を起点とした新規Ⅱ型ポリケチド生合成機構の解明2023
- Author(s)
  日比玄紀, 白石太郎, 梅村龍槻, 西山真, 葛山智久
- Organizer
  第65回天然有機化合物討論会
- Data Source
  KAKENHI-PLANNED-22H05120
[Presentation] 特殊アミノ酸シスペンタシンの生産とその生合成機構の解析2022
- Author(s)
  日比玄紀, 梅村龍槻, 白石太郎, 西山真, 葛山智久
- Organizer
  日本農芸化学会関東支部2022年度大会
- Data Source
  KAKENHI-PLANNED-22H05120
[Presentation] Biosynthesis of the acyl side chain of the nucleotide antibiotic A-94964 produced by Streptomyces sp. SANK 604042022
- Author(s)
  Hao Xu, Taro Shiraishi, Tomohisa Kuzuyama
- Organizer
  日本放線菌学会2022年度大会
- Data Source
  KAKENHI-PLANNED-22H05120
[Presentation] 放線菌由来非タンパク質性アミノ酸シスペンタシンの生合成機構2022
- Author(s)
  日比玄紀、白石太郎、葛山智久
- Organizer
  日本放線菌学会2022年度大会
- Data Source
  KAKENHI-PLANNED-22H05120
[Presentation] Biosynthesis of the nucleoside-derived natural product angustmycin2021
- Author(s)
  Jiaqi XIA, Taro SHIRAISHI, Tomohisa KUZUYAMA
- Organizer
  日本農芸化学会2021年度大会
- Data Source
  KAKENHI-PLANNED-16H06453
[Presentation] ペプチジルヌクレオシド系抗生物質Amipurimycinの生合成に関する研究2018
- Author(s)
  池内　秀雄、白石　太郎、新家　一男、西山　真、葛山　智久
- Organizer
  日本農芸化学会2018年度大会
- Data Source
  KAKENHI-PLANNED-16H06453
[Presentation] Biosynthesis of the Nucleoside Antibiotic A-949642017
- Author(s)
  Shiraishi, T., Nishiyama, M., Kuzuyama, T.
- Organizer
  US-Japan Seminar on the Biosynthesis of Natural Products for Young Researchers
- Place of Presentation
  東京工業大学（東京都目黒区）
- Year and Date
  2017-03-04
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06453
[Presentation] Biosynthetic studies on the antituberculous agent caprazamycin2017
- Author(s)
  Taro Shiraishi
- Organizer
  Directing Biosynthesis V
- Place of Presentation
  コベントリー（英国）
- Year and Date
  2017-03-22
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06453
[Presentation] Investigating Biosynthetic of the Antituberculous Agent Caprazamycin2017
- Author(s)
  Taro Shiraishi, Makoto Nishiyama, Tomohisa Kuzuyama
- Organizer
  International Symposium on Biology of Actinomycetes
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06453
[Presentation] カプラザマイシン生合成における小タンパク質を介したアシル化反応の発見2017
- Author(s)
  白石太郎、廣昇、五十嵐雅之、西山真、葛山智久
- Organizer
  日本農芸化学会2017年度大会
- Place of Presentation
  京都女子大学（京都府東山区）
- Data Source
  KAKENHI-PLANNED-16H06453
[Presentation] カプラザマイシン生合成に関与する特異なメチル基転移酵素の機能解析2017
- Author(s)
  白石　太郎、五十嵐　雅之、西山真、葛山　智久
- Organizer
  日本放線菌学会2017年度大会
- Data Source
  KAKENHI-PLANNED-16H06453
[Presentation] Biosynthesis of the antituberculous agent caprazamycin2016
- Author(s)
  Taro Shiraishi, Makoto Nishiyama and Tomohisa Kuzuyama
- Organizer
  2016 SIMB Annual Meeting and Exhibition
- Place of Presentation
  ニューオーリンズ（米国）
- Year and Date
  2016-07-24
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06453
[Presentation] アシル化反応に関与する新奇キャリアタンパク質の発見2016
- Author(s)
  白石太郎、廣昇、五十嵐雅之、西山真、葛山智久
- Organizer
  日本放線菌学会2016年度大会
- Place of Presentation
  東京大学（東京都文京区）
- Year and Date
  2016-09-08
- Data Source
  KAKENHI-PLANNED-16H06453

1. Kuzuyama Tomohisa (30280952)

# of Collaborated Projects: 2 results

# of Collaborated Products: 30 results
2. 吉田彩子 (90633686)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
3. 小川哲弘 (40323480)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. 森脇由隆 (70751303)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Shiraishi Taro 白石 太郎

白石 太郎 シライシ タロウ

Research Projects

Research Products

Co-Researchers

Development of a Next-Generation Enzyme-Substrate Complex Prediction Method Considering the Reaction Information and Predicted 3D Structure

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

天然物BGCにコードされた輸送体の解析手法の確立と機能解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

天然物生合成機構の改変による革新的ペプチド－核酸融合化合物ライブラリーの構築Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

構造多様性一挙構築型生体反応の集積・予知・創出

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development and precise functional analysis of innovative biosynthetic machinery to create complex skeletons

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Discovery of type II polyketide synthase-like enzymes for the biosynthesis of cispentacin2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Complete Biosynthetic Pathway of the Phosphonate Phosphonothrixin: Two Distinct Thiamine Diphosphate-Dependent Enzymes Divide the Work to Form a C-C Bond2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Biosynthetic pathways and enzymes involved in the production of phosphonic acid natural products2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 新奇骨格を創成する革新的生合成マシナリーの開拓2019

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Recent advances in the biosynthesis of nucleoside antibiotics2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The Amipurimycin and Miharamycin Biosynthetic Gene Clusters: Unraveling the Origins of 2-Aminopurinyl Peptidyl Nucleoside Antibiotics2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Biosynthesis of the uridine-derived nucleoside antibiotic A-94964: Identification and characterization of the biosynthetic gene cluster provide insight into the biosynthetic pathway2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Fosfomycin Biosynthesis via Transient Cytidylylation of 2-Hydroxyethylphosphonate by the Bifunctional Fom1 Enzyme2017

Author(s)

Journal Title

Data Source

[Presentation] 計算科学を用いた真菌由来テルペン環化酵素の反応機構解析2024

Author(s)

Organizer

Shiraishi Taro 白石太郎

白石太郎シライシタロウ